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PRJEB1986: zebrafish developmental stages transcriptome

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Results for spi2+spic

Z-value: 1.43

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Transcription factors associated with spi2+spic

Gene Symbol Gene ID Gene Info
spic
ENSDARG00000012435 Spi-C transcription factor (Spi-1/PU.1 related)
spi2
ENSDARG00000087438 Spi-2 proto-oncogene

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
spi2dr11_v1_chr4_-_17803784_178037840.418.5e-02Click!
spicdr11_v1_chr4_-_17812131_178121310.194.4e-01Click!

Activity profile of spi2+spic motif

Sorted Z-values of spi2+spic motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_51998708 2.37 ENSDART00000097194
serinc5
serine incorporator 5
chr1_-_21723329 1.82 ENSDART00000137138
si:ch211-134c9.2
si:ch211-134c9.2
chr22_+_5135193 1.79 ENSDART00000106156
mydgf
myeloid-derived growth factor
chr5_+_24086227 1.76 ENSDART00000051549
ENSDART00000177458
ENSDART00000135934
tp53
tumor protein p53
chr5_-_51166025 1.76 ENSDART00000097471
card9
caspase recruitment domain family, member 9
chr8_-_50888806 1.70 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr20_+_36812368 1.68 ENSDART00000062931
abracl
ABRA C-terminal like
chr17_-_28811747 1.68 ENSDART00000001444
g2e3
G2/M-phase specific E3 ubiquitin protein ligase
chr3_-_16719244 1.65 ENSDART00000055859
pold1
polymerase (DNA directed), delta 1, catalytic subunit
chr2_+_38288308 1.59 ENSDART00000170672
nedd8l
neural precursor cell expressed, developmentally down-regulated 8, like
chr19_-_37508571 1.59 ENSDART00000018255
ilf2
interleukin enhancer binding factor 2
chr17_+_53428092 1.57 ENSDART00000192509
srsf10b
serine/arginine-rich splicing factor 10b
chr9_+_35843732 1.56 ENSDART00000020638
rcan1a
regulator of calcineurin 1a
chr4_-_17353100 1.55 ENSDART00000134467
ENSDART00000189019
parpbp
PARP1 binding protein
chr6_-_39903393 1.54 ENSDART00000085945
tsfm
Ts translation elongation factor, mitochondrial
chr19_-_42607451 1.54 ENSDART00000004392
fkbp9
FK506 binding protein 9
chr8_-_16725959 1.53 ENSDART00000183593
depdc1a
DEP domain containing 1a
chr7_-_18554603 1.48 ENSDART00000108938
msantd1
Myb/SANT-like DNA-binding domain containing 1
chr9_+_32649088 1.48 ENSDART00000136136
ENSDART00000172033
rabl3
RAB, member of RAS oncogene family-like 3
chr5_+_37087583 1.47 ENSDART00000049900
tagln2
transgelin 2
chr23_-_40766518 1.44 ENSDART00000127420
si:dkeyp-27c8.2
si:dkeyp-27c8.2
chr19_+_4038589 1.41 ENSDART00000169271
btr23
bloodthirsty-related gene family, member 23
chr9_-_24218367 1.40 ENSDART00000135356
nabp1a
nucleic acid binding protein 1a
chr1_+_26110985 1.40 ENSDART00000054208
mtap
methylthioadenosine phosphorylase
chr8_-_52715911 1.39 ENSDART00000168241
tubb2b
tubulin, beta 2b
chr13_+_29519115 1.37 ENSDART00000086711
chst3a
carbohydrate (chondroitin 6) sulfotransferase 3a
chr7_+_24023653 1.35 ENSDART00000141165
tinf2
TERF1 (TRF1)-interacting nuclear factor 2
chr12_+_27536270 1.35 ENSDART00000133719
etv4
ets variant 4
chr15_-_5901514 1.35 ENSDART00000155252
si:ch73-281n10.2
si:ch73-281n10.2
chr8_+_15277874 1.34 ENSDART00000146965
dnttip2
deoxynucleotidyltransferase, terminal, interacting protein 2
chr6_+_43400059 1.33 ENSDART00000143374
mitfa
microphthalmia-associated transcription factor a
chr8_+_39634114 1.33 ENSDART00000144293
msi1
musashi RNA-binding protein 1
chr22_-_28373698 1.32 ENSDART00000157592
si:ch211-213c4.5
si:ch211-213c4.5
chr4_-_11603149 1.31 ENSDART00000150468
net1
neuroepithelial cell transforming 1
chr24_+_36392040 1.29 ENSDART00000136057
arf2b
ADP-ribosylation factor 2b
chr17_+_38295847 1.29 ENSDART00000008532
mbip
MAP3K12 binding inhibitory protein 1
chr5_+_36899691 1.29 ENSDART00000132322
hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr6_+_29707129 1.29 ENSDART00000023549
ENSDART00000164849
phb2b
prohibitin 2b
chr17_-_43022468 1.28 ENSDART00000002945
NPC2 (1 of many)
zgc:193725
chr2_+_35595454 1.27 ENSDART00000098734
cacybp
calcyclin binding protein
chr17_+_53427931 1.26 ENSDART00000101091
srsf10b
serine/arginine-rich splicing factor 10b
chr12_+_9497646 1.26 ENSDART00000137643
ENSDART00000152605
dnajc9
DnaJ (Hsp40) homolog, subfamily C, member 9
chr19_-_5669122 1.26 ENSDART00000112211
si:ch211-264f5.2
si:ch211-264f5.2
chr10_+_13209580 1.25 ENSDART00000000887
ENSDART00000136932
rassf6
Ras association (RalGDS/AF-6) domain family 6
chr6_-_40768654 1.25 ENSDART00000184668
ENSDART00000146470
arpc4
actin related protein 2/3 complex, subunit 4
chr20_+_13141408 1.24 ENSDART00000034098
dtl
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr1_-_55888970 1.24 ENSDART00000064194
asf1bb
anti-silencing function 1Bb histone chaperone
chr7_+_25015151 1.24 ENSDART00000149966
ENSDART00000175583
b3gat3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr7_+_71764883 1.22 ENSDART00000166865
myl12.1
myosin, light chain 12, genome duplicate 1
chr9_-_55128839 1.21 ENSDART00000085135
tbl1x
transducin beta like 1 X-linked
chr14_-_31862657 1.21 ENSDART00000172870
ENSDART00000007927
ENSDART00000134748
ENSDART00000128730
rbmx
RNA binding motif protein, X-linked
chr12_+_18899396 1.21 ENSDART00000105858
xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr19_+_30423117 1.20 ENSDART00000023074
mrps18b
mitochondrial ribosomal protein S18B
chr1_-_44484 1.20 ENSDART00000171547
ENSDART00000164075
ENSDART00000168091
tmem39a
transmembrane protein 39A
chr9_-_32648725 1.19 ENSDART00000123374
dnajb11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr16_+_46684855 1.19 ENSDART00000058325
lamtor2
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr14_-_16807206 1.18 ENSDART00000157957
tcirg1b
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr17_+_34244345 1.16 ENSDART00000006058
eif2s1a
eukaryotic translation initiation factor 2, subunit 1 alpha a
chr5_+_68826514 1.16 ENSDART00000061406
usp39
ubiquitin specific peptidase 39
chr3_-_40528333 1.14 ENSDART00000193047
actb2
actin, beta 2
chr13_+_11829072 1.12 ENSDART00000079356
ENSDART00000170160
sufu
suppressor of fused homolog (Drosophila)
chr7_+_24814866 1.12 ENSDART00000173581
si:ch211-226l4.6
si:ch211-226l4.6
chr5_-_8171625 1.11 ENSDART00000167643
slc1a3a
solute carrier family 1 (glial high affinity glutamate transporter), member 3a
chr11_+_6882049 1.11 ENSDART00000075998
klhl26
kelch-like family member 26
chr17_-_45387134 1.11 ENSDART00000010975
tmem206
transmembrane protein 206
chr17_-_48705993 1.10 ENSDART00000030934
kcnk5a
potassium channel, subfamily K, member 5a
chr19_+_14158075 1.10 ENSDART00000170335
ENSDART00000168260
nudc
nudC nuclear distribution protein
chr6_+_27090800 1.10 ENSDART00000121558
atg4b
autophagy related 4B, cysteine peptidase
chr4_+_9177997 1.10 ENSDART00000057254
ENSDART00000154614
nfyba
nuclear transcription factor Y, beta a
chr24_+_36392486 1.09 ENSDART00000007381
ENSDART00000135898
arf2b
ADP-ribosylation factor 2b
chr8_-_13735572 1.08 ENSDART00000139642
si:dkey-258f14.7
si:dkey-258f14.7
chr1_-_38907943 1.08 ENSDART00000136102
vegfc
vascular endothelial growth factor c
chr21_+_18907102 1.07 ENSDART00000160185
ENSDART00000190175
ENSDART00000017937
ENSDART00000191546
ENSDART00000130519
ENSDART00000137143
smpd4
sphingomyelin phosphodiesterase 4
chr6_+_13506841 1.07 ENSDART00000032331
gmppab
GDP-mannose pyrophosphorylase Ab
chr3_-_35865040 1.07 ENSDART00000102952
suz12a
SUZ12 polycomb repressive complex 2a subunit
chr16_+_33655890 1.06 ENSDART00000143757
fhl3a
four and a half LIM domains 3a
chr24_-_31092711 1.06 ENSDART00000168398
hccsb
holocytochrome c synthase b
chr18_-_35407530 1.05 ENSDART00000137663
snrpa
small nuclear ribonucleoprotein polypeptide A
chr14_+_12178915 1.05 ENSDART00000054626
hdac3
histone deacetylase 3
chr2_+_35612621 1.05 ENSDART00000143082
si:dkey-4i23.5
si:dkey-4i23.5
chr23_-_4225830 1.05 ENSDART00000170455
aar2
AAR2 splicing factor homolog (S. cerevisiae)
chr24_-_23839647 1.04 ENSDART00000125190
rrs1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr17_-_51121525 1.04 ENSDART00000130412
ENSDART00000013418
aqr
aquarius intron-binding spliceosomal factor
chr2_-_38287987 1.04 ENSDART00000185329
ENSDART00000061677
si:ch211-14a17.6
si:ch211-14a17.6
chr18_-_7056702 1.04 ENSDART00000127397
ENSDART00000148774
utp15
utp15, U3 small nucleolar ribonucleoprotein, homolog
chr18_-_35407289 1.04 ENSDART00000012018
snrpa
small nuclear ribonucleoprotein polypeptide A
chr21_+_26522571 1.03 ENSDART00000134617
adssl
adenylosuccinate synthase, like
chr7_-_57637779 1.03 ENSDART00000028017
mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast)
chr5_-_25733745 1.03 ENSDART00000051566
zgc:101016
zgc:101016
chr16_+_33931032 1.03 ENSDART00000167240
snip1
Smad nuclear interacting protein
chr12_+_48815988 1.03 ENSDART00000149089
anxa11b
annexin A11b
chr20_-_30900947 1.03 ENSDART00000153419
ENSDART00000062536
hebp2
heme binding protein 2
chr12_-_49168398 1.03 ENSDART00000186608
FO704624.1

chr3_+_46380086 1.02 ENSDART00000055129
polr3k
polymerase (RNA) III (DNA directed) polypeptide K
chr23_+_24955394 1.02 ENSDART00000142124
nol9
nucleolar protein 9
chr14_-_14687004 1.02 ENSDART00000169970
gcna
germ cell nuclear acidic peptidase
chr21_-_9769500 1.01 ENSDART00000170710
arhgap24
Rho GTPase activating protein 24
chr4_-_20108833 1.01 ENSDART00000100867
fam3c
family with sequence similarity 3, member C
chr8_+_15251448 0.99 ENSDART00000063717
zgc:171480
zgc:171480
chr1_+_6225493 0.99 ENSDART00000145378
fastkd2
FAST kinase domains 2
chr24_+_36392784 0.99 ENSDART00000134750
arf2b
ADP-ribosylation factor 2b
chr8_+_46217861 0.99 ENSDART00000038790
angptl7
angiopoietin-like 7
chr3_-_34561624 0.99 ENSDART00000129313
sept9a
septin 9a
chr17_-_19535328 0.98 ENSDART00000077809
cyp26c1
cytochrome P450, family 26, subfamily C, polypeptide 1
chr12_-_7607114 0.98 ENSDART00000158095
slc16a9b
solute carrier family 16, member 9b
chr21_+_18950575 0.98 ENSDART00000036172
crkl
v-crk avian sarcoma virus CT10 oncogene homolog-like
chr2_-_65529 0.97 ENSDART00000192876
zgc:153913
zgc:153913
chr1_-_46505310 0.97 ENSDART00000178072
si:busm1-105l16.2
si:busm1-105l16.2
chr11_+_3959495 0.97 ENSDART00000122953
gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr19_-_31765615 0.96 ENSDART00000103636
si:dkeyp-120h9.1
si:dkeyp-120h9.1
chr11_+_34921492 0.96 ENSDART00000128070
gnai2a
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a
chr16_+_26020886 0.96 ENSDART00000113534
mrpl17
mitochondrial ribosomal protein L17
chr11_-_6868474 0.96 ENSDART00000168372
lsm4
LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
chr15_-_14064302 0.95 ENSDART00000156384
BX927244.1

chr10_+_44984946 0.95 ENSDART00000182520
h2afvb
H2A histone family, member Vb
chr11_+_23569869 0.94 ENSDART00000163418
si:ch73-21d24.1
si:ch73-21d24.1
chr12_+_27099943 0.94 ENSDART00000066278
ttll6
tubulin tyrosine ligase-like family, member 6
chr17_+_41081977 0.94 ENSDART00000137091
ENSDART00000143714
babam2
BRISC and BRCA1 A complex member 2
chr8_+_16726386 0.93 ENSDART00000144621
smim15
small integral membrane protein 15
chr14_-_706345 0.93 ENSDART00000166632
si:zfos-741a10.3
si:zfos-741a10.3
chr1_-_55270966 0.93 ENSDART00000152807
si:ch211-286b5.5
si:ch211-286b5.5
chr9_-_27719998 0.93 ENSDART00000161068
ENSDART00000148195
ENSDART00000138386
gtf2e1
general transcription factor IIE, polypeptide 1, alpha
chr19_+_20177887 0.93 ENSDART00000008595
tra2a
transformer 2 alpha homolog
chr16_+_43765993 0.93 ENSDART00000149154
si:dkey-122a22.2
si:dkey-122a22.2
chr9_+_27720428 0.93 ENSDART00000112415
lcmt2
leucine carboxyl methyltransferase 2
chr13_-_36418921 0.93 ENSDART00000135804
dcaf5
ddb1 and cul4 associated factor 5
chr4_-_4261673 0.93 ENSDART00000150694
cd9b
CD9 molecule b
chr8_+_45361775 0.92 ENSDART00000015193
chmp4bb
charged multivesicular body protein 4Bb
chr21_-_31207522 0.92 ENSDART00000191637
zgc:152891
zgc:152891
chr3_-_58644920 0.92 ENSDART00000155953
dhrs7ca
dehydrogenase/reductase (SDR family) member 7Ca
chr4_-_1068155 0.92 ENSDART00000172320
mtpn
myotrophin
chr1_+_15258641 0.92 ENSDART00000033018
pi4k2b
phosphatidylinositol 4-kinase type 2 beta
chr7_+_24390939 0.92 ENSDART00000087494
ENSDART00000125463
haus3
HAUS augmin-like complex, subunit 3
chr2_+_33926911 0.92 ENSDART00000109849
ENSDART00000135884
kif2c
kinesin family member 2C
chr3_-_5030089 0.92 ENSDART00000167153
polr3h
polymerase (RNA) III (DNA directed) polypeptide H
chr5_+_27421639 0.92 ENSDART00000146285
cyb561a3a
cytochrome b561 family, member A3a
chr5_-_24029228 0.91 ENSDART00000051546
rps6ka3a
ribosomal protein S6 kinase a, polypeptide 3a
chr1_-_12394048 0.91 ENSDART00000146067
ENSDART00000134708
sclt1
sodium channel and clathrin linker 1
chr18_-_35407695 0.90 ENSDART00000191845
ENSDART00000141703
snrpa
small nuclear ribonucleoprotein polypeptide A
chr11_+_2172335 0.89 ENSDART00000170593
hoxc12b
homeobox C12b
chr13_+_30035253 0.89 ENSDART00000181303
ENSDART00000057525
ENSDART00000136622
dnajb12a
DnaJ (Hsp40) homolog, subfamily B, member 12a
chr7_+_57088920 0.89 ENSDART00000024076
scamp2l
secretory carrier membrane protein 2, like
chr16_-_17586883 0.89 ENSDART00000017142
m6pr
mannose-6-phosphate receptor (cation dependent)
chr12_+_638435 0.89 ENSDART00000152508
si:ch211-176g6.1
si:ch211-176g6.1
chr4_-_21466480 0.89 ENSDART00000139962
pawr
PRKC, apoptosis, WT1, regulator
chr3_+_62196672 0.89 ENSDART00000097312
sco1
SCO1 cytochrome c oxidase assembly protein
chr4_-_25812329 0.89 ENSDART00000146658
tmcc3
transmembrane and coiled-coil domain family 3
chr4_-_18741942 0.89 ENSDART00000145747
ENSDART00000066980
ENSDART00000186518
atxn10
ataxin 10
chr6_-_14038804 0.88 ENSDART00000184606
ENSDART00000184609
etv5b
ets variant 5b
chr7_-_19526721 0.88 ENSDART00000114203
man2b2
mannosidase, alpha, class 2B, member 2
chr24_+_29352039 0.87 ENSDART00000101641
prmt6
protein arginine methyltransferase 6
chr15_-_34934784 0.87 ENSDART00000190848
dhx16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr9_+_34950942 0.87 ENSDART00000077800
tfdp1a
transcription factor Dp-1, a
chr7_-_26049282 0.87 ENSDART00000136389
ENSDART00000101124
rnaseka
ribonuclease, RNase K a
chr23_-_44871987 0.86 ENSDART00000085764
wu:fb72h05
wu:fb72h05
chr19_+_18627100 0.85 ENSDART00000167245
vps52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr21_-_25604603 0.85 ENSDART00000133134
ENSDART00000139460
efemp2b
EGF containing fibulin extracellular matrix protein 2b
chr21_+_19347655 0.85 ENSDART00000093155
hpse
heparanase
chr25_-_37489917 0.84 ENSDART00000160688
psma1
proteasome subunit alpha 1
chr6_-_31806345 0.84 ENSDART00000149369
si:dkey-209n16.2
si:dkey-209n16.2
chr1_-_45347393 0.84 ENSDART00000173024
si:ch211-243a20.4
si:ch211-243a20.4
chr3_+_32099507 0.83 ENSDART00000044238
zgc:92066
zgc:92066
chr21_+_30937690 0.83 ENSDART00000022562
rhogb
ras homolog family member Gb
chr25_+_16880990 0.83 ENSDART00000020259
zgc:77158
zgc:77158
chr15_+_34939906 0.82 ENSDART00000131182
si:ch73-95l15.3
si:ch73-95l15.3
chr10_+_5954787 0.82 ENSDART00000161887
ENSDART00000160345
ENSDART00000190046
map3k1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr24_+_264839 0.82 ENSDART00000066872
ccr12b.2
chemokine (C-C motif) receptor 12b, tandem duplicate 2
chr7_+_25221757 0.82 ENSDART00000173551
exoc6b
exocyst complex component 6B
chr20_-_34711528 0.82 ENSDART00000061555
si:ch211-63o20.7
si:ch211-63o20.7
chr21_-_25756119 0.81 ENSDART00000002341
cldnc
claudin c
chr4_-_43056627 0.81 ENSDART00000150269
si:dkey-54j5.2
si:dkey-54j5.2
chr5_+_23913585 0.81 ENSDART00000015401
ercc6l
excision repair cross-complementation group 6-like
chr21_+_34981263 0.81 ENSDART00000132711
rbm11
RNA binding motif protein 11
chr5_-_23464970 0.80 ENSDART00000141028
si:dkeyp-20g2.1
si:dkeyp-20g2.1
chr3_-_32603191 0.80 ENSDART00000150997
si:ch73-248e21.7
si:ch73-248e21.7
chr23_-_4225606 0.79 ENSDART00000014152
ENSDART00000133341
aar2
AAR2 splicing factor homolog (S. cerevisiae)
chr5_+_50953240 0.79 ENSDART00000148501
ENSDART00000149892
ENSDART00000190312
col4a3bpa
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr7_+_26545911 0.79 ENSDART00000135313
tnk1
tyrosine kinase, non-receptor, 1
chr1_-_55942055 0.78 ENSDART00000142371
si:ch73-343l4.2
si:ch73-343l4.2
chr17_-_6451801 0.78 ENSDART00000064700
fuca2
alpha-L-fucosidase 2
chr22_-_27709692 0.78 ENSDART00000172458
CR547131.1

chr4_+_2637947 0.77 ENSDART00000130623
dus4l
dihydrouridine synthase 4-like (S. cerevisiae)
chr1_+_22691256 0.77 ENSDART00000017413
zmynd10
zinc finger, MYND-type containing 10
chr19_+_47476908 0.77 ENSDART00000157886
zgc:114119
zgc:114119
chr19_-_45960191 0.77 ENSDART00000052434
ENSDART00000172732
eif3hb
eukaryotic translation initiation factor 3, subunit H, b
chr4_-_14191717 0.77 ENSDART00000147928
pus7l
pseudouridylate synthase 7-like
chr18_+_31073265 0.77 ENSDART00000023539
cyba
cytochrome b-245, alpha polypeptide
chr7_+_19495905 0.76 ENSDART00000125584
ENSDART00000173774
si:ch211-212k18.8
si:ch211-212k18.8
chr7_+_19600262 0.76 ENSDART00000007310
zgc:171731
zgc:171731
chr6_+_28141135 0.76 ENSDART00000113405
ENSDART00000179795
inpp5d
inositol polyphosphate-5-phosphatase D
chr4_+_76745015 0.76 ENSDART00000155883
ms4a17a.10
membrane-spanning 4-domains, subfamily A, member 17A.10
chr2_-_38312757 0.76 ENSDART00000167274
ap1g2
adaptor-related protein complex 1, gamma 2 subunit
chr2_-_14793343 0.76 ENSDART00000132264
si:ch73-366i20.1
si:ch73-366i20.1
chr7_-_33351485 0.76 ENSDART00000146420
anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr10_+_24690534 0.76 ENSDART00000079549
tpte
transmembrane phosphatase with tensin homology
chr23_-_35649000 0.75 ENSDART00000053310
tmem18
transmembrane protein 18
chr2_+_24304854 0.75 ENSDART00000078972
fitm1
fat storage-inducing transmembrane protein 1
chr5_-_24882357 0.75 ENSDART00000127773
ENSDART00000003998
ENSDART00000143851
ewsr1b
EWS RNA-binding protein 1b
chr6_-_7123210 0.75 ENSDART00000041304
atg3
autophagy related 3
chr9_-_30555725 0.75 ENSDART00000079222
chaf1b
chromatin assembly factor 1, subunit B

Network of associatons between targets according to the STRING database.

First level regulatory network of spi2+spic

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0010525 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.5 1.6 GO:0001120 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.5 1.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.5 1.5 GO:0001779 natural killer cell differentiation(GO:0001779)
0.5 1.4 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.4 1.7 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.4 2.0 GO:0071267 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.4 1.5 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.4 2.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.3 1.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3 0.9 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.3 0.9 GO:0044878 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.3 0.9 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.3 1.1 GO:1900181 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.3 0.8 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.3 2.2 GO:0072401 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.3 1.1 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.3 1.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.3 0.8 GO:0036159 inner dynein arm assembly(GO:0036159)
0.3 1.0 GO:0042779 tRNA 3'-trailer cleavage(GO:0042779)
0.3 1.8 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.2 0.7 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 0.7 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.2 1.2 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.2 1.2 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.2 1.2 GO:0048855 adenohypophysis morphogenesis(GO:0048855)
0.2 0.7 GO:0080182 histone H3-K4 trimethylation(GO:0080182) histone H3-K36 dimethylation(GO:0097676)
0.2 0.9 GO:0034969 histone arginine methylation(GO:0034969)
0.2 0.6 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.2 1.1 GO:0017006 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.2 1.0 GO:0033238 regulation of cellular amino acid metabolic process(GO:0006521) regulation of cellular amine metabolic process(GO:0033238)
0.2 0.6 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.2 0.9 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2 3.5 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.2 1.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.2 1.0 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.2 0.5 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.2 1.0 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.2 1.0 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.2 0.7 GO:0010039 response to iron ion(GO:0010039)
0.2 1.0 GO:0055014 outflow tract morphogenesis(GO:0003151) atrial cardiac muscle cell development(GO:0055014)
0.2 0.5 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 2.2 GO:0035108 limb morphogenesis(GO:0035108)
0.1 0.4 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.1 1.0 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 0.7 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.4 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.1 0.9 GO:0033034 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 2.1 GO:0045116 protein neddylation(GO:0045116)
0.1 0.8 GO:1902623 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.1 0.6 GO:0000966 RNA 5'-end processing(GO:0000966) germ-line stem cell population maintenance(GO:0030718)
0.1 1.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 1.1 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.5 GO:1904182 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.1 0.6 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 0.8 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 1.0 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 0.6 GO:0032979 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.1 0.5 GO:0055021 regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
0.1 0.8 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 1.0 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 0.4 GO:0045730 respiratory burst(GO:0045730)
0.1 0.6 GO:0042264 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.1 0.8 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.7 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.8 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.1 1.9 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 0.6 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.1 1.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.6 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 2.6 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 0.4 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 0.4 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.1 1.0 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) rRNA 3'-end processing(GO:0031125)
0.1 1.4 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.1 1.0 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 0.5 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 1.7 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.1 1.8 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.1 0.4 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 0.3 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.1 2.1 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.1 0.7 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 4.0 GO:0032456 endocytic recycling(GO:0032456)
0.1 1.0 GO:0035587 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 1.2 GO:0002138 retinoic acid biosynthetic process(GO:0002138)
0.1 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.1 GO:0019323 pentose catabolic process(GO:0019323)
0.1 0.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 1.3 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
0.1 0.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.2 GO:1903358 regulation of Golgi organization(GO:1903358)
0.1 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.9 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.5 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.1 0.3 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 0.4 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.1 0.6 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365) aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.1 0.3 GO:0046103 adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.1 1.4 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.1 1.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.4 GO:0003232 bulbus arteriosus development(GO:0003232)
0.1 1.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.6 GO:0043490 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 0.6 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.2 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 0.7 GO:0006999 nuclear pore organization(GO:0006999)
0.1 1.0 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.4 GO:0035627 ceramide transport(GO:0035627)
0.1 0.8 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 1.2 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.1 0.6 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.1 1.2 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 0.5 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.1 0.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.8 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.5 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.5 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.2 GO:0048313 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.0 0.9 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.9 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 1.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.4 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.6 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.5 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 1.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.7 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.4 GO:0042987 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.0 0.3 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.5 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 1.0 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.7 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 2.2 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.8 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 1.0 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.9 GO:0010883 regulation of lipid storage(GO:0010883)
0.0 0.2 GO:0071422 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) C4-dicarboxylate transport(GO:0015740) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.2 GO:0050930 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.0 0.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 16.7 GO:0006397 mRNA processing(GO:0006397)
0.0 0.4 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.0 0.5 GO:0007340 acrosome reaction(GO:0007340)
0.0 1.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.4 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.7 GO:0045047 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.3 GO:0008216 spermidine metabolic process(GO:0008216)
0.0 1.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.8 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.3 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.7 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.7 GO:0042476 odontogenesis(GO:0042476)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.9 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.5 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.6 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.5 GO:0007032 endosome organization(GO:0007032)
0.0 0.8 GO:0043588 skin development(GO:0043588)
0.0 0.1 GO:0097264 self proteolysis(GO:0097264)
0.0 0.4 GO:0006958 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.0 3.0 GO:0006457 protein folding(GO:0006457)
0.0 0.5 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.6 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.9 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.5 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.3 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.1 GO:0035675 neuromast hair cell development(GO:0035675)
0.0 1.2 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.6 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.3 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.6 GO:0007041 lysosomal transport(GO:0007041)
0.0 0.4 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.2 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 1.1 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.1 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.3 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.3 GO:0006956 complement activation(GO:0006956)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 1.1 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.9 GO:0051225 spindle assembly(GO:0051225)
0.0 0.8 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.3 GO:0031297 replication fork processing(GO:0031297)
0.0 0.2 GO:0032094 response to food(GO:0032094)
0.0 0.6 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 1.0 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.0 0.3 GO:0099590 postsynaptic neurotransmitter receptor internalization(GO:0098884) neurotransmitter receptor internalization(GO:0099590)
0.0 0.2 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.7 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.1 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.6 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.2 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.8 GO:0003401 axis elongation(GO:0003401)
0.0 0.9 GO:0048916 posterior lateral line development(GO:0048916)
0.0 4.5 GO:0006412 translation(GO:0006412)
0.0 0.1 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.3 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.0 0.7 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.9 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.3 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.1 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.2 GO:0035476 angioblast cell migration(GO:0035476)
0.0 0.4 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.1 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.3 GO:0032392 DNA geometric change(GO:0032392) DNA duplex unwinding(GO:0032508)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.6 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.4 1.2 GO:0043614 multi-eIF complex(GO:0043614)
0.3 1.7 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.3 1.6 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.3 1.1 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.3 1.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.2 1.4 GO:0070876 SOSS complex(GO:0070876)
0.2 1.1 GO:0097433 dense body(GO:0097433)
0.2 0.6 GO:0097361 CIA complex(GO:0097361)
0.2 0.8 GO:0098842 postsynaptic early endosome(GO:0098842)
0.2 1.2 GO:0070062 extracellular exosome(GO:0070062)
0.2 0.7 GO:0033186 CAF-1 complex(GO:0033186)
0.2 1.0 GO:0071986 Ragulator complex(GO:0071986)
0.2 0.5 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 0.6 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.2 1.5 GO:0005688 U6 snRNP(GO:0005688)
0.1 0.4 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 1.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 3.0 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.9 GO:0070552 BRISC complex(GO:0070552)
0.1 0.5 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.8 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.6 GO:1990923 PET complex(GO:1990923)
0.1 0.6 GO:0070449 elongin complex(GO:0070449)
0.1 1.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.9 GO:0070652 HAUS complex(GO:0070652)
0.1 1.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.8 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.5 GO:0070390 transcription export complex 2(GO:0070390)
0.1 1.2 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1 1.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.2 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.1 0.8 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.6 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.3 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.1 0.8 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.5 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.7 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 3.3 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.7 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.8 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.7 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.9 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.4 GO:0070847 core mediator complex(GO:0070847)
0.1 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.7 GO:0002102 podosome(GO:0002102)
0.1 0.8 GO:0070187 telosome(GO:0070187)
0.1 0.3 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.3 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 1.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 3.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.1 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 3.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.0 GO:0000776 kinetochore(GO:0000776)
0.0 2.1 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.1 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 5.2 GO:0005730 nucleolus(GO:0005730)
0.0 1.7 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.8 GO:0005814 centriole(GO:0005814)
0.0 0.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.9 GO:0005840 ribosome(GO:0005840)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)
0.0 1.1 GO:0042383 sarcolemma(GO:0042383)
0.0 0.5 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.4 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.8 GO:0030863 cortical cytoskeleton(GO:0030863)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.4 3.4 GO:0030619 U1 snRNA binding(GO:0030619)
0.3 1.4 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.3 1.3 GO:0044548 S100 protein binding(GO:0044548)
0.3 1.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3 0.9 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.3 1.1 GO:0008905 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.3 0.8 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.3 1.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 1.1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.2 0.7 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 0.7 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.2 1.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 1.5 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.2 0.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 1.1 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.2 0.6 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.2 1.5 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.2 0.6 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 1.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 0.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.2 1.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 1.7 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.2 1.7 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 0.6 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 0.9 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 1.0 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.8 GO:0015616 DNA translocase activity(GO:0015616)
0.1 1.1 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.9 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.5 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.6 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 0.8 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 1.2 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.4 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 0.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.8 GO:0008515 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.5 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 1.6 GO:0031386 protein tag(GO:0031386)
0.1 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.5 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.4 GO:1902388 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 1.3 GO:0051117 ATPase binding(GO:0051117)
0.1 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.4 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 2.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 1.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.1 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.6 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.6 GO:0034584 piRNA binding(GO:0034584)
0.1 0.9 GO:0005537 mannose binding(GO:0005537)
0.1 0.6 GO:0032977 membrane insertase activity(GO:0032977)
0.1 0.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 0.9 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 1.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 1.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.6 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.7 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.0 GO:0032190 acrosin binding(GO:0032190)
0.1 1.0 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.6 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.4 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.1 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175) superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.7 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.8 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.5 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.9 GO:0017069 snRNA binding(GO:0017069)
0.0 0.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 1.1 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.7 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 1.1 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 1.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.6 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.2 GO:0015140 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 1.0 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 2.6 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.3 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 2.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 5.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 1.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.9 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 1.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 1.3 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.8 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 9.6 GO:0005525 GTP binding(GO:0005525)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.9 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.5 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.4 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0050661 NADP binding(GO:0050661)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.2 1.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 2.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 3.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 1.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.0 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling
0.0 1.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.2 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 1.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.2 1.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 2.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.7 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.5 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 1.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.5 REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
0.1 1.0 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 1.1 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.9 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 2.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 5.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.8 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 1.2 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.8 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 1.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.0 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.5 REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX Genes involved in Formation of RNA Pol II elongation complex
0.0 0.7 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.6 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 1.1 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 1.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.6 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.4 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.1 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0 0.8 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism