Project

PRJEB1986: zebrafish developmental stages transcriptome

Navigation
Downloads

Results for srfa+srfb

Z-value: 2.11

Motif logo

logo of

Transcription factors associated with srfa+srfb

Gene Symbol Gene ID Gene Info
srfa
ENSDARG00000053918 serum response factor a
srfb
ENSDARG00000102867 serum response factor b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
srfbdr11_v1_chr13_-_51922290_51922290-0.771.3e-04Click!
srfadr11_v1_chr22_+_35089031_350890310.145.6e-01Click!

Activity profile of srfa+srfb motif

Sorted Z-values of srfa+srfb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_21336385 23.84 ENSDART00000054460
egr1
early growth response 1
chr15_-_551177 14.86 ENSDART00000066774
ENSDART00000154617
tagln
transgelin
chr8_+_40628926 8.85 ENSDART00000163598
dusp2
dual specificity phosphatase 2
chr9_-_44948488 8.23 ENSDART00000059228
vil1
villin 1
chr11_+_25459697 7.33 ENSDART00000161481
opn1sw2
opsin 1 (cone pigments), short-wave-sensitive 2
chr2_+_58221163 7.24 ENSDART00000157939
FO704813.1

chr21_+_30043054 6.95 ENSDART00000065448
fabp6
fatty acid binding protein 6, ileal (gastrotropin)
chr17_-_15611744 5.37 ENSDART00000010496
fhl5
four and a half LIM domains 5
chr23_+_45579497 5.29 ENSDART00000110381
egr4
early growth response 4
chr5_-_32309129 5.21 ENSDART00000123003
myhz1.1
myosin, heavy polypeptide 1.1, skeletal muscle
chr5_-_32292965 5.17 ENSDART00000183522
ENSDART00000131983
myhz1.2
myosin, heavy polypeptide 1.2, skeletal muscle
chr8_+_10561922 4.86 ENSDART00000133348
fam19a5l
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5-like
chr11_-_34097418 4.80 ENSDART00000028301
ENSDART00000138579
tdo2b
tryptophan 2,3-dioxygenase b
chr3_-_35602233 4.69 ENSDART00000055269
gng13b
guanine nucleotide binding protein (G protein), gamma 13b
chr12_-_35054354 4.63 ENSDART00000075351
zgc:112285
zgc:112285
chr2_+_31804582 4.52 ENSDART00000086646
rnf182
ring finger protein 182
chr25_+_33192796 4.46 ENSDART00000125892
ENSDART00000121680
ENSDART00000014851
TPM1 (1 of many)
zgc:171719
chr21_+_6780340 4.39 ENSDART00000139493
ENSDART00000140478
olfm1b
olfactomedin 1b
chr23_+_44611864 4.34 ENSDART00000145905
ENSDART00000132361
eno3
enolase 3, (beta, muscle)
chr17_-_20979077 4.25 ENSDART00000006676
phyhipla
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr20_-_46554440 4.17 ENSDART00000043298
ENSDART00000060680
fosab
v-fos FBJ murine osteosarcoma viral oncogene homolog Ab
chr12_-_26064480 4.01 ENSDART00000158215
ENSDART00000171206
ENSDART00000171212
ENSDART00000182956
ENSDART00000186779
ldb3b
LIM domain binding 3b
chr3_+_45401472 4.00 ENSDART00000156693
baiap3
BAI1-associated protein 3
chr20_-_29420713 3.83 ENSDART00000147464
ryr3
ryanodine receptor 3
chr3_-_40976463 3.79 ENSDART00000128450
ENSDART00000018676
cyp3c1
cytochrome P450, family 3, subfamily c, polypeptide 1
chr25_+_33192404 3.78 ENSDART00000193592
TPM1 (1 of many)
zgc:171719
chr19_-_42424599 3.63 ENSDART00000077042
zgc:153441
zgc:153441
chr8_+_50727220 3.54 ENSDART00000127062
egr3
early growth response 3
chr7_+_29952169 3.54 ENSDART00000173540
ENSDART00000173940
ENSDART00000173906
ENSDART00000173772
ENSDART00000173506
ENSDART00000039657
tpma
alpha-tropomyosin
chr3_-_22228602 3.49 ENSDART00000017750
myl4
myosin, light chain 4, alkali; atrial, embryonic
chr5_+_9428876 3.35 ENSDART00000081791
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr7_-_18168493 3.22 ENSDART00000127428
peli3
pellino E3 ubiquitin protein ligase family member 3
chr23_-_16692312 3.06 ENSDART00000046784
fkbp1ab
FK506 binding protein 1Ab
chr23_+_42813415 3.01 ENSDART00000055577
myl9a
myosin, light chain 9a, regulatory
chr20_-_40750953 2.99 ENSDART00000061256
cx28.9
connexin 28.9
chr12_-_26064105 2.92 ENSDART00000168825
ldb3b
LIM domain binding 3b
chr4_+_12612723 2.82 ENSDART00000133767
lmo3
LIM domain only 3
chr18_+_36769758 2.82 ENSDART00000180375
ENSDART00000136463
ENSDART00000133487
ENSDART00000130206
fosb
FBJ murine osteosarcoma viral oncogene homolog B
chr11_+_40657612 2.76 ENSDART00000183271
slc45a1
solute carrier family 45, member 1
chr2_+_15100742 2.75 ENSDART00000027171
f3b
coagulation factor IIIb
chr6_-_55309190 2.74 ENSDART00000162117
ube2c
ubiquitin-conjugating enzyme E2C
chr3_-_33395233 2.70 ENSDART00000167349
si:dkey-283b1.6
si:dkey-283b1.6
chr22_+_33362552 2.63 ENSDART00000101580
nicn1
nicolin 1
chr20_-_14875308 2.62 ENSDART00000141290
dnm3a
dynamin 3a
chr7_+_29951997 2.58 ENSDART00000173453
tpma
alpha-tropomyosin
chr13_-_9598320 2.49 ENSDART00000184613
cpxm1a
carboxypeptidase X (M14 family), member 1a
chr7_-_53117131 2.48 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cdh1
cadherin 1, type 1, E-cadherin (epithelial)
chr4_-_16644708 2.42 ENSDART00000042307
sinhcaf
SIN3-HDAC complex associated factor
chr20_-_47732703 2.37 ENSDART00000193975
tfap2d
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr18_+_36770166 2.35 ENSDART00000078151
fosb
FBJ murine osteosarcoma viral oncogene homolog B
chr7_-_66868543 2.34 ENSDART00000149680
ampd3a
adenosine monophosphate deaminase 3a
chr20_+_9211237 2.33 ENSDART00000139527
si:ch211-59d15.4
si:ch211-59d15.4
chr15_+_8043751 2.33 ENSDART00000193701
cadm2b
cell adhesion molecule 2b
chr20_+_13969414 2.32 ENSDART00000049864
rd3
retinal degeneration 3
chr23_-_45439903 2.30 ENSDART00000170729
NPNT (1 of many)
nephronectin
chr17_+_13763425 2.28 ENSDART00000105175
lrfn5a
leucine rich repeat and fibronectin type III domain containing 5a
chr1_-_14332283 2.23 ENSDART00000090025
wfs1a
Wolfram syndrome 1a (wolframin)
chr7_-_71758307 2.19 ENSDART00000161067
ENSDART00000165253
myom1b
myomesin 1b
chr4_+_27898833 2.14 ENSDART00000146099
cerk
ceramide kinase
chr10_+_8101729 2.10 ENSDART00000138875
ENSDART00000123447
ENSDART00000185333
pstpip2
proline-serine-threonine phosphatase interacting protein 2
chr10_+_42169982 2.06 ENSDART00000190905
CU467905.1

chr12_-_15584479 2.05 ENSDART00000150134
acbd4
acyl-CoA binding domain containing 4
chr12_-_29624638 2.03 ENSDART00000126744
nrg3b
neuregulin 3b
chr23_-_44207349 2.00 ENSDART00000186276
zgc:158659
zgc:158659
chr1_+_50976975 1.98 ENSDART00000022290
ENSDART00000140982
mdh1aa
malate dehydrogenase 1Aa, NAD (soluble)
chr2_-_37477654 1.96 ENSDART00000193921
dapk3
death-associated protein kinase 3
chr1_+_9071324 1.95 ENSDART00000184194
BX004779.2

chr11_-_24016761 1.95 ENSDART00000153601
ENSDART00000067817
ENSDART00000170531
chia.3
chitinase, acidic.3
chr3_-_40945710 1.95 ENSDART00000138719
ENSDART00000102416
cyp3c4
cytochrome P450, family 3, subfamily C, polypeptide 4
chr22_-_29336268 1.93 ENSDART00000132776
ENSDART00000186351
ENSDART00000121599
pdgfba
platelet-derived growth factor beta polypeptide a
chr18_-_14941840 1.93 ENSDART00000091729
mlc1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr11_-_2250767 1.88 ENSDART00000018131
hnrnpa1a
heterogeneous nuclear ribonucleoprotein A1a
chr4_+_5180650 1.88 ENSDART00000067390
fgf6b
fibroblast growth factor 6b
chr24_+_31277360 1.87 ENSDART00000165993
f3a
coagulation factor IIIa
chr12_-_20120702 1.85 ENSDART00000153387
ENSDART00000158412
ENSDART00000112768
ubald1a
UBA-like domain containing 1a
chr12_-_35095414 1.83 ENSDART00000153229
si:dkey-21e13.3
si:dkey-21e13.3
chr23_-_35064785 1.76 ENSDART00000172240
BX294434.1

chr20_+_53577502 1.76 ENSDART00000126983
myh6
myosin, heavy chain 6, cardiac muscle, alpha
chr3_+_32553714 1.75 ENSDART00000165638
pax10
paired box 10
chr12_+_17100021 1.69 ENSDART00000177923
acta2
actin, alpha 2, smooth muscle, aorta
chr13_+_24279021 1.65 ENSDART00000058629
acta1b
actin, alpha 1b, skeletal muscle
chr20_+_40150612 1.65 ENSDART00000143680
ENSDART00000109681
ENSDART00000101041
ENSDART00000121818
trdn
triadin
chr2_+_30916188 1.63 ENSDART00000137012
myom1a
myomesin 1a (skelemin)
chr10_-_7892192 1.62 ENSDART00000145480
smtna
smoothelin a
chr20_-_2949028 1.62 ENSDART00000104667
ENSDART00000193151
ENSDART00000131946
cdk19
cyclin-dependent kinase 19
chr10_-_7857494 1.60 ENSDART00000143215
inpp5ja
inositol polyphosphate-5-phosphatase Ja
chr12_+_42436328 1.60 ENSDART00000167324
ebf3a
early B cell factor 3a
chr19_+_43715911 1.59 ENSDART00000006344
cap1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr6_-_13498745 1.55 ENSDART00000027684
ENSDART00000189438
mylkb
myosin light chain kinase b
chr1_+_44173245 1.55 ENSDART00000159450
ENSDART00000106048
ENSDART00000157763
ctnnd1
catenin (cadherin-associated protein), delta 1
chr10_-_15910974 1.54 ENSDART00000148169
pip5k1ba
phosphatidylinositol-4-phosphate 5-kinase, type I, beta a
chr7_-_22324843 1.54 ENSDART00000187408
CU571061.1

chr4_-_6623645 1.49 ENSDART00000060861
foxp2
forkhead box P2
chr13_-_40398556 1.46 ENSDART00000191921
nkx3.3
NK3 homeobox 3
chr18_+_45504362 1.45 ENSDART00000140089
cngb1a
cyclic nucleotide gated channel beta 1a
chr11_+_37178271 1.43 ENSDART00000161771
itih3b
inter-alpha-trypsin inhibitor heavy chain 3b
chr2_+_38264964 1.42 ENSDART00000182068
dhrs1
dehydrogenase/reductase (SDR family) member 1
chr13_+_23132666 1.39 ENSDART00000164639
sorbs1
sorbin and SH3 domain containing 1
chr1_+_9994811 1.37 ENSDART00000143719
ENSDART00000110749
si:dkeyp-75b4.10
si:dkeyp-75b4.10
chr13_-_18695289 1.37 ENSDART00000176809
sfxn3
sideroflexin 3
chr11_-_472547 1.34 ENSDART00000005923
zgc:77375
zgc:77375
chr10_-_29816467 1.33 ENSDART00000055913
hist2h2l
histone 2, H2, like
chr21_+_8533533 1.28 ENSDART00000077924
FO834888.1

chr3_-_37351225 1.27 ENSDART00000174685
si:ch211-278a6.1
si:ch211-278a6.1
chr5_-_55395964 1.25 ENSDART00000145791
prune2
prune homolog 2 (Drosophila)
chr12_-_20373058 1.24 ENSDART00000066382
aqp8a.1
aquaporin 8a, tandem duplicate 1
chr2_-_24269911 1.23 ENSDART00000099532
myh7
myosin heavy chain 7
chr10_-_690072 1.22 ENSDART00000164871
ENSDART00000142833
glis3
GLIS family zinc finger 3
chr1_+_57331813 1.21 ENSDART00000152440
ENSDART00000062841
epn3b
epsin 3b
chr7_+_56651759 1.20 ENSDART00000073600
kcng4b
potassium voltage-gated channel, subfamily G, member 4b
chr14_+_48964628 1.19 ENSDART00000105427
mif
macrophage migration inhibitory factor
chr22_-_11493236 1.15 ENSDART00000002691
tspan7b
tetraspanin 7b
chr3_-_18410968 1.10 ENSDART00000041842
ndufb10
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10
chr14_+_17137023 1.10 ENSDART00000080712
slc43a3b
solute carrier family 43, member 3b
chr5_-_41845116 1.09 ENSDART00000112382
si:dkey-65b12.6
si:dkey-65b12.6
chr20_+_1996202 1.08 ENSDART00000184143
CABZ01092781.1

chr8_+_26268726 1.05 ENSDART00000180883
slc26a6
solute carrier family 26, member 6
chr21_+_4509483 1.03 ENSDART00000025612
phyhd1
phytanoyl-CoA dioxygenase domain containing 1
chr1_-_37383741 0.99 ENSDART00000193155
ENSDART00000191887
ENSDART00000189077
scpp1
secretory calcium-binding phosphoprotein 1
chr8_+_36942262 0.97 ENSDART00000188173
iqsec2b
IQ motif and Sec7 domain 2b
chr12_+_35654749 0.95 ENSDART00000169889
ENSDART00000167873
baiap2b
BAI1-associated protein 2b
chr25_-_19031019 0.94 ENSDART00000191707
cacna2d4b
calcium channel, voltage-dependent, alpha 2/delta subunit 4b
chr21_+_4508959 0.93 ENSDART00000140432
ENSDART00000147187
ENSDART00000148910
phyhd1
phytanoyl-CoA dioxygenase domain containing 1
chr17_-_25326296 0.90 ENSDART00000168822
pabpc4
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr7_+_47243564 0.86 ENSDART00000098942
ENSDART00000162237
znf507
zinc finger protein 507
chr13_+_8840772 0.84 ENSDART00000059321
epcam
epithelial cell adhesion molecule
chr23_-_37514493 0.77 ENSDART00000083267
dnajc16
DnaJ (Hsp40) homolog, subfamily C, member 16
chr2_-_24270062 0.77 ENSDART00000192445
myh7
myosin heavy chain 7
chr3_-_32898626 0.75 ENSDART00000103201
kat7a
K(lysine) acetyltransferase 7a
chr9_-_202805 0.74 ENSDART00000182260
CABZ01067557.1

chr17_+_45454943 0.74 ENSDART00000074838
kcnk3b
potassium channel, subfamily K, member 3b
chr3_-_2592350 0.70 ENSDART00000192325
si:dkey-217f16.5
si:dkey-217f16.5
chr6_+_58915889 0.67 ENSDART00000083628
ddit3
DNA-damage-inducible transcript 3
chr4_-_22310956 0.63 ENSDART00000162585
hcls1
hematopoietic cell-specific Lyn substrate 1
chr21_+_25765734 0.62 ENSDART00000021664
cldnb
claudin b
chr3_+_23707691 0.62 ENSDART00000025449
hoxb5a
homeobox B5a
chr15_-_42760110 0.61 ENSDART00000152490
si:ch211-181d7.3
si:ch211-181d7.3
chr7_+_24522308 0.61 ENSDART00000173542
btr09
bloodthirsty-related gene family, member 9
chr7_-_71758613 0.61 ENSDART00000166724
myom1b
myomesin 1b
chr13_-_50002852 0.58 ENSDART00000099439
lyst
lysosomal trafficking regulator
chr25_-_893464 0.57 ENSDART00000159321
znf609a
zinc finger protein 609a
chr10_+_29771256 0.57 ENSDART00000193195
hyou1
hypoxia up-regulated 1
chr20_+_20186706 0.56 ENSDART00000002507
rhoj
ras homolog family member J
chr16_-_31675669 0.56 ENSDART00000168848
ENSDART00000158331
c1r
complement component 1, r subcomponent
chr21_-_25555355 0.55 ENSDART00000144228
si:dkey-17e16.9
si:dkey-17e16.9
chr11_+_6281647 0.54 ENSDART00000002459
ctns
cystinosin, lysosomal cystine transporter
chr22_-_36856405 0.53 ENSDART00000029588
kng1
kininogen 1
chr1_+_55293424 0.53 ENSDART00000152464
zgc:172106
zgc:172106
chr2_+_47718605 0.53 ENSDART00000189180
ENSDART00000148824
mbnl1
muscleblind-like splicing regulator 1
chr12_+_20693743 0.52 ENSDART00000153023
ENSDART00000153370
st6galnac1.2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, tandem duplicate 2
chr16_-_31754102 0.49 ENSDART00000185043
ptpn6
protein tyrosine phosphatase, non-receptor type 6
chr18_+_50669456 0.48 ENSDART00000163005
si:dkey-151j17.4
si:dkey-151j17.4
chr3_+_1724941 0.44 ENSDART00000193402
BX321875.2

chr21_+_21811867 0.42 ENSDART00000185752
neu3.4
sialidase 3 (membrane sialidase), tandem duplicate 4
chr20_+_46572550 0.40 ENSDART00000139051
ENSDART00000161320
batf
basic leucine zipper transcription factor, ATF-like
chr14_+_164556 0.40 ENSDART00000185606
WDR1
WD repeat domain 1
chr14_-_32824380 0.32 ENSDART00000172791
ENSDART00000105745
inppl1b
inositol polyphosphate phosphatase-like 1b
chr21_-_31286428 0.30 ENSDART00000185334
ca4c
carbonic anhydrase IV c
chr14_-_25309058 0.30 ENSDART00000159569
htr4
5-hydroxytryptamine receptor 4
chr1_+_6307305 0.28 ENSDART00000183870
LO018629.1

chr23_-_44466257 0.28 ENSDART00000150126
si:ch1073-228j22.2
si:ch1073-228j22.2
chr13_-_25303303 0.27 ENSDART00000133153
plaua
plasminogen activator, urokinase a
chr6_-_41135215 0.27 ENSDART00000001861
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr18_-_26675699 0.27 ENSDART00000113280
FRMD5
si:ch211-69m14.1
chr4_-_17642168 0.25 ENSDART00000007030
klhl42
kelch-like family, member 42
chr22_-_17458070 0.25 ENSDART00000139658
si:ch211-197g15.10
si:ch211-197g15.10
chr10_-_373575 0.25 ENSDART00000114487
DMPK
DM1 protein kinase
chr1_-_6494384 0.23 ENSDART00000109356
klf7a
Kruppel-like factor 7a
chr16_+_23816933 0.23 ENSDART00000183428
si:dkey-7f3.9
si:dkey-7f3.9
chr3_-_56896702 0.21 ENSDART00000023265
ush1ga
Usher syndrome 1Ga (autosomal recessive)
chr4_-_49133107 0.19 ENSDART00000150806
znf1146
zinc finger protein 1146
chr14_-_10492072 0.14 ENSDART00000182525
lpar4
lysophosphatidic acid receptor 4
chr19_+_348729 0.13 ENSDART00000114284
mcl1a
MCL1, BCL2 family apoptosis regulator a
chr25_-_19486399 0.13 ENSDART00000155076
ENSDART00000156016
zgc:193812
zgc:193812
chr22_-_382955 0.12 ENSDART00000082406
ora3
olfactory receptor class A related 3
chr1_+_44173506 0.10 ENSDART00000170512
ctnnd1
catenin (cadherin-associated protein), delta 1
chr23_+_36118738 0.09 ENSDART00000139319
hoxc5a
homeobox C5a
chr15_-_39945036 0.07 ENSDART00000192481
msh5
mutS homolog 5
chr13_-_9070754 0.06 ENSDART00000143783
ENSDART00000102121
ENSDART00000140820
ENSDART00000184210
si:dkey-112g5.12
si:dkey-112g5.12
chr1_+_8492379 0.05 ENSDART00000184518
myo15ab
myosin XVAb
chr10_-_32920690 0.02 ENSDART00000136245
cux1a
cut-like homeobox 1a
chr1_+_52560549 0.01 ENSDART00000167514
abca1a
ATP-binding cassette, sub-family A (ABC1), member 1A
chr16_-_12496632 0.00 ENSDART00000019941
slc2a3b
solute carrier family 2 (facilitated glucose transporter), member 3b
chr8_+_14986833 0.00 ENSDART00000171867
ENSDART00000191374
fnbp1l
formin binding protein 1-like

Network of associatons between targets according to the STRING database.

First level regulatory network of srfa+srfb

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.2 GO:0072673 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.6 3.2 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.6 4.8 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.6 23.8 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.5 4.3 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.5 7.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.4 2.5 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.4 4.8 GO:0050909 sensory perception of taste(GO:0050909)
0.4 1.2 GO:0055057 neuroblast division(GO:0055057)
0.4 2.0 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.4 1.8 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.3 2.0 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.3 4.2 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.2 3.2 GO:0008078 mesodermal cell migration(GO:0008078)
0.2 1.9 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.2 1.6 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.2 0.5 GO:0090131 mesenchyme migration(GO:0090131)
0.2 1.9 GO:0006032 chitin catabolic process(GO:0006032)
0.2 1.9 GO:0034394 protein localization to cell surface(GO:0034394)
0.2 1.0 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.2 0.7 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.2 2.3 GO:0032264 IMP salvage(GO:0032264)
0.1 2.6 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.4 GO:0001562 response to protozoan(GO:0001562) defense response to protozoan(GO:0042832)
0.1 1.2 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 5.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 1.0 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 3.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.5 GO:0045471 response to ethanol(GO:0045471)
0.1 1.3 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 1.9 GO:0001757 somite specification(GO:0001757)
0.1 0.5 GO:0070293 renal absorption(GO:0070293)
0.1 0.6 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 2.1 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.1 1.5 GO:1990798 pancreas regeneration(GO:1990798)
0.1 4.7 GO:0007596 blood coagulation(GO:0007596)
0.1 0.9 GO:0046549 retinal cone cell development(GO:0046549)
0.1 6.1 GO:0061515 myeloid cell development(GO:0061515)
0.1 2.2 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.5 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 1.4 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.3 GO:0033628 regulation of cell adhesion mediated by integrin(GO:0033628)
0.0 0.4 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 2.4 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.6 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.6 GO:0010842 retina layer formation(GO:0010842)
0.0 0.7 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0 2.1 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 1.0 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0032098 regulation of appetite(GO:0032098)
0.0 1.9 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 3.0 GO:0016485 protein processing(GO:0016485)
0.0 1.9 GO:0043068 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 1.4 GO:1990542 mitochondrial transmembrane transport(GO:1990542)
0.0 1.3 GO:0046474 glycerophospholipid biosynthetic process(GO:0046474)
0.0 0.6 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 1.9 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.6 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.8 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0 1.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 4.0 GO:0006887 exocytosis(GO:0006887)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 8.2 GO:0032433 filopodium tip(GO:0032433)
0.5 4.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 2.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 4.4 GO:0031430 M band(GO:0031430)
0.2 2.4 GO:0016580 Sin3 complex(GO:0016580)
0.2 2.0 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 8.5 GO:0031941 filamentous actin(GO:0031941)
0.1 2.6 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 2.2 GO:0005869 dynactin complex(GO:0005869)
0.1 2.5 GO:0030057 desmosome(GO:0030057)
0.1 5.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 13.3 GO:0016459 myosin complex(GO:0016459)
0.1 1.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 4.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.4 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.6 GO:0001726 ruffle(GO:0001726)
0.0 2.2 GO:0000786 nucleosome(GO:0000786)
0.0 2.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.2 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.6 GO:0005911 cell-cell junction(GO:0005911)
0.0 1.3 GO:0014069 postsynaptic density(GO:0014069)
0.0 13.8 GO:0005615 extracellular space(GO:0005615)
0.0 3.6 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
1.2 7.0 GO:0032052 bile acid binding(GO:0032052)
1.0 23.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.7 2.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.5 0.5 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.5 4.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.5 7.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.4 2.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.4 2.0 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.4 1.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.3 6.9 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.3 2.8 GO:0008506 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 0.7 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.2 1.4 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.2 4.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 1.9 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.2 2.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 2.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 1.6 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.2 1.9 GO:0004568 chitinase activity(GO:0004568)
0.1 7.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 1.2 GO:0015250 water channel activity(GO:0015250)
0.1 1.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 1.2 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 5.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 1.4 GO:0005222 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 2.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.0 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 5.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 1.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.9 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 3.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 2.1 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.1 3.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 19.3 GO:0051015 actin filament binding(GO:0051015)
0.1 2.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.4 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 4.6 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 2.0 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 2.5 GO:0051213 dioxygenase activity(GO:0051213)
0.0 3.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.5 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 32.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.3 2.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.2 2.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 15.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 3.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 5.2 PID AP1 PATHWAY AP-1 transcription factor network
0.1 1.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 0.5 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 2.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.8 24.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.8 2.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 4.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 2.0 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 7.7 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 2.7 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 1.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 4.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors