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PRJEB1986: zebrafish developmental stages transcriptome

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Results for stat5a+stat5b

Z-value: 0.71

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Transcription factors associated with stat5a+stat5b

Gene Symbol Gene ID Gene Info
stat5a
ENSDARG00000019392 signal transducer and activator of transcription 5a
stat5b
ENSDARG00000055588 signal transducer and activator of transcription 5b
stat5a
ENSDARG00000113871 signal transducer and activator of transcription 5a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
stat5adr11_v1_chr3_+_17314997_17314997-0.845.5e-06Click!
stat5bdr11_v1_chr12_-_13650344_136504720.019.6e-01Click!

Activity profile of stat5a+stat5b motif

Sorted Z-values of stat5a+stat5b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_49819027 2.34 ENSDART00000067824
b3galnt2
beta-1,3-N-acetylgalactosaminyltransferase 2
chr1_+_230363 2.02 ENSDART00000153285
tfdp1b
transcription factor Dp-1, b
chr22_-_26005894 1.94 ENSDART00000105088
pdgfaa
platelet-derived growth factor alpha polypeptide a
chr22_-_26100282 1.87 ENSDART00000166075
pdgfaa
platelet-derived growth factor alpha polypeptide a
chr18_-_49318823 1.70 ENSDART00000098419
sb:cb81
sb:cb81
chr25_+_31323978 1.67 ENSDART00000067030
lsp1
lymphocyte-specific protein 1
chr6_+_45934682 1.65 ENSDART00000103489
cenps
centromere protein S
chr15_-_23485752 1.65 ENSDART00000152706
nlrx1
NLR family member X1
chr3_-_45281350 1.60 ENSDART00000020168
kctd5a
potassium channel tetramerization domain containing 5a
chr15_+_2857556 1.46 ENSDART00000157758
mre11a
MRE11 homolog A, double strand break repair nuclease
chr19_+_15443063 1.34 ENSDART00000151732
lin28a
lin-28 homolog A (C. elegans)
chr2_-_42035250 1.33 ENSDART00000056460
ENSDART00000140788
gbp1
guanylate binding protein 1
chr3_-_32541033 1.26 ENSDART00000151476
ENSDART00000055324
rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr18_-_20444296 1.18 ENSDART00000132993
kif23
kinesin family member 23
chr2_-_14793343 1.16 ENSDART00000132264
si:ch73-366i20.1
si:ch73-366i20.1
chr11_+_30321116 1.15 ENSDART00000187921
ENSDART00000127075
ugt1b1
UDP glucuronosyltransferase 1 family, polypeptide B1
chr20_+_25586099 1.15 ENSDART00000063122
ENSDART00000134047
cyp2p10
cytochrome P450, family 2, subfamily P, polypeptide 10
chr7_+_26029672 1.14 ENSDART00000101126
alox12
arachidonate 12-lipoxygenase
chr20_+_28803642 1.12 ENSDART00000188526
fntb
farnesyltransferase, CAAX box, beta
chr8_+_247163 1.06 ENSDART00000122378
cep120
centrosomal protein 120
chr21_-_32284532 1.04 ENSDART00000190676
clk4b
CDC-like kinase 4b
chr20_+_17581881 1.01 ENSDART00000182832
cdh2
cadherin 2, type 1, N-cadherin (neuronal)
chr3_-_46818001 0.98 ENSDART00000166505
elavl3
ELAV like neuron-specific RNA binding protein 3
chr17_-_24521382 0.95 ENSDART00000092948
peli1b
pellino E3 ubiquitin protein ligase 1b
chr11_+_13024002 0.95 ENSDART00000104113
btf3l4
basic transcription factor 3-like 4
chr15_-_44052927 0.95 ENSDART00000166209
wu:fb44b02
wu:fb44b02
chr24_+_13635108 0.94 ENSDART00000183008
trpa1b
transient receptor potential cation channel, subfamily A, member 1b
chr13_+_6092135 0.93 ENSDART00000162738
fam120b
family with sequence similarity 120B
chr6_-_37499574 0.91 ENSDART00000023163
jade3
jade family PHD finger 3
chr16_+_25171832 0.90 ENSDART00000156416
wu:fe05a04
wu:fe05a04
chr16_-_41787421 0.90 ENSDART00000147210
si:dkey-199f5.8
si:dkey-199f5.8
chr16_+_9762261 0.90 ENSDART00000020654
psmd4b
proteasome 26S subunit, non-ATPase 4b
chr7_+_17106160 0.88 ENSDART00000190048
ENSDART00000180004
ENSDART00000013409
prmt3
protein arginine methyltransferase 3
chr21_+_37090585 0.84 ENSDART00000182971
znf346
zinc finger protein 346
chr6_+_16870004 0.84 ENSDART00000154794
pimr21
Pim proto-oncogene, serine/threonine kinase, related 21
chr5_+_32141790 0.82 ENSDART00000041504
tescb
tescalcin b
chr4_-_49952636 0.81 ENSDART00000157941
si:dkey-156k2.3
si:dkey-156k2.3
chr10_-_8434816 0.81 ENSDART00000108643
tctn1
tectonic family member 1
chr22_-_9861531 0.80 ENSDART00000193197
si:dkey-253d23.2
si:dkey-253d23.2
chr7_-_38687431 0.79 ENSDART00000074490
aplnr2
apelin receptor 2
chr14_+_6953244 0.78 ENSDART00000159470
rack1
receptor for activated C kinase 1
chr17_-_43517542 0.78 ENSDART00000133665
mrpl35
mitochondrial ribosomal protein L35
chr2_-_42109575 0.77 ENSDART00000075551
adhfe1
alcohol dehydrogenase, iron containing, 1
chr17_-_6536305 0.76 ENSDART00000154855
cenpo
centromere protein O
chr1_+_33322555 0.75 ENSDART00000113486
mxra5a
matrix-remodelling associated 5a
chr9_-_49860756 0.73 ENSDART00000044270
ttc21b
tetratricopeptide repeat domain 21B
chr4_-_1818315 0.72 ENSDART00000067433
ube2nb
ubiquitin-conjugating enzyme E2Nb
chr6_-_43283122 0.72 ENSDART00000186022
frmd4ba
FERM domain containing 4Ba
chr5_+_29160324 0.70 ENSDART00000137324
dpp7
dipeptidyl-peptidase 7
chr11_+_16040517 0.70 ENSDART00000111284
agtrap
angiotensin II receptor-associated protein
chr15_-_25083200 0.66 ENSDART00000156053
pimr191
Pim proto-oncogene, serine/threonine kinase, related 191
chr19_+_7759354 0.65 ENSDART00000151400
ubap2l
ubiquitin associated protein 2-like
chr17_-_6536466 0.63 ENSDART00000188735
cenpo
centromere protein O
chr15_+_37412883 0.58 ENSDART00000156474
zbtb32
zinc finger and BTB domain containing 32
chr8_-_28342487 0.56 ENSDART00000108508
kdm5bb
lysine (K)-specific demethylase 5Bb
chr6_+_16895685 0.56 ENSDART00000154090
pimr28
Pim proto-oncogene, serine/threonine kinase, related 28
chr8_-_31053872 0.56 ENSDART00000109885
snrnp200
small nuclear ribonucleoprotein 200 (U5)
chr21_-_14692119 0.55 ENSDART00000123047
ehmt1b
euchromatic histone-lysine N-methyltransferase 1b
chr8_+_25959940 0.54 ENSDART00000143011
ENSDART00000140626
si:dkey-72l14.4
si:dkey-72l14.4
chr20_+_48754045 0.54 ENSDART00000062578
zgc:110348
zgc:110348
chr14_+_22132388 0.53 ENSDART00000109065
ccng1
cyclin G1
chr4_+_13586455 0.52 ENSDART00000187230
tnpo3
transportin 3
chr15_+_29088426 0.51 ENSDART00000187290
si:ch211-137a8.4
si:ch211-137a8.4
chr8_-_47212686 0.51 ENSDART00000040370
pimr189
Pim proto-oncogene, serine/threonine kinase, related 189
chr17_+_46864116 0.51 ENSDART00000156250
pimr27
Pim proto-oncogene, serine/threonine kinase, related 27
chr19_-_43757568 0.48 ENSDART00000058491
ppt1
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr24_-_25166720 0.47 ENSDART00000141601
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr17_+_12255642 0.47 ENSDART00000155175
pimr175
Pim proto-oncogene, serine/threonine kinase, related 175
chr8_-_36618073 0.46 ENSDART00000047912
gpkow
G patch domain and KOW motifs
chr20_+_37294112 0.45 ENSDART00000076293
ENSDART00000140450
cx23
connexin 23
chr3_-_46817838 0.45 ENSDART00000028610
elavl3
ELAV like neuron-specific RNA binding protein 3
chr3_-_6608342 0.44 ENSDART00000161188
si:ch73-59f11.3
si:ch73-59f11.3
chr14_-_6987649 0.43 ENSDART00000060990
eif4ebp3l
eukaryotic translation initiation factor 4E binding protein 3, like
chr6_-_3998199 0.42 ENSDART00000059212
unc50
unc-50 homolog (C. elegans)
chr2_-_22659450 0.42 ENSDART00000115025
thap4
THAP domain containing 4
chr20_-_3238110 0.41 ENSDART00000008077
spint1b
serine peptidase inhibitor, Kunitz type 1 b
chr17_+_11372531 0.41 ENSDART00000130975
ENSDART00000149366
timm9
translocase of inner mitochondrial membrane 9 homolog
chr4_-_1497384 0.41 ENSDART00000093236
zmp:0000000711
zmp:0000000711
chr6_-_53048291 0.40 ENSDART00000103267
fam212ab
family with sequence similarity 212, member Ab
chr11_+_16040680 0.39 ENSDART00000157703
agtrap
angiotensin II receptor-associated protein
chr6_-_18393476 0.38 ENSDART00000168309
trim25
tripartite motif containing 25
chr15_-_3282220 0.38 ENSDART00000092942
slc25a15a
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15a
chr15_-_32383529 0.35 ENSDART00000028349
c4
complement component 4
chr5_-_42878178 0.35 ENSDART00000162981
CXCL11 (1 of many)
C-X-C motif chemokine ligand 11
chr1_+_57040472 0.35 ENSDART00000181365
si:ch211-1f22.16
si:ch211-1f22.16
chr7_+_17560808 0.33 ENSDART00000159699
ENSDART00000165724
ENSDART00000129017
ENSDART00000101955
nitr1b
novel immune-type receptor 1b
chr25_+_34749812 0.32 ENSDART00000185712
wwp2
WW domain containing E3 ubiquitin protein ligase 2
chr9_+_18572970 0.31 ENSDART00000114860
lacc1
laccase (multicopper oxidoreductase) domain containing 1
chr7_+_17303944 0.29 ENSDART00000163505
ENSDART00000162169
ENSDART00000161291
nitr9
novel immune-type receptor 9
chr10_-_7821686 0.28 ENSDART00000121531
mat2aa
methionine adenosyltransferase II, alpha a
chr4_+_57580303 0.28 ENSDART00000166492
ENSDART00000103025
ENSDART00000170786
il17ra1b
il17ra2
interleukin 17 receptor A1b
interleukin 17 receptor A2
chr5_-_16791223 0.27 ENSDART00000192744
atad1a
ATPase family, AAA domain containing 1a
chr8_+_19548985 0.26 ENSDART00000123104
notch2
notch 2
chr6_-_37749711 0.26 ENSDART00000078324
nipa1
non imprinted in Prader-Willi/Angelman syndrome 1
chr15_-_31401361 0.25 ENSDART00000124360
or111-7
odorant receptor, family D, subfamily 111, member 7
chr15_-_2857961 0.25 ENSDART00000033263
ankrd49
ankyrin repeat domain 49
chr15_-_25010400 0.24 ENSDART00000155236
si:ch211-198e20.10
si:ch211-198e20.10
chr1_+_33322174 0.23 ENSDART00000140435
mxra5a
matrix-remodelling associated 5a
chr15_-_15449929 0.22 ENSDART00000101918
proca1
protein interacting with cyclin A1
chr15_-_29556757 0.22 ENSDART00000060049
hspa13
heat shock protein 70 family, member 13
chr4_+_34599803 0.20 ENSDART00000134088
pimr168
Pim proto-oncogene, serine/threonine kinase, related 168
chr24_-_25166416 0.19 ENSDART00000111552
ENSDART00000169495
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr16_+_25126935 0.19 ENSDART00000058945
zgc:92590
zgc:92590
chr22_-_16180467 0.18 ENSDART00000171331
ENSDART00000185607
vcam1b
vascular cell adhesion molecule 1b
chr17_-_46933567 0.18 ENSDART00000157274
pimr25
Pim proto-oncogene, serine/threonine kinase, related 25
chr8_+_10920205 0.18 ENSDART00000179742
BX321886.1

chr2_-_37140423 0.18 ENSDART00000144220
tspan37
tetraspanin 37
chr10_+_36299541 0.18 ENSDART00000166138
or106-7
odorant receptor, family G, subfamily 106, member 7
chr7_+_34786591 0.18 ENSDART00000173700
si:dkey-148a17.5
si:dkey-148a17.5
chr17_-_46817295 0.17 ENSDART00000155904
pimr24
Pim proto-oncogene, serine/threonine kinase, related 24
chr13_+_2861265 0.17 ENSDART00000170602
ENSDART00000171687
XPO5
si:ch211-233m11.2
chr4_-_57571688 0.17 ENSDART00000160179
pimr168
Pim proto-oncogene, serine/threonine kinase, related 168
chr15_-_25039083 0.16 ENSDART00000154409
pimr190
Pim proto-oncogene, serine/threonine kinase, related 190
chr6_-_17266221 0.16 ENSDART00000155448
pimr18
Pim proto-oncogene, serine/threonine kinase, related 18
chr17_-_24439672 0.16 ENSDART00000155020
wdpcp
WD repeat containing planar cell polarity effector
chr24_+_31374324 0.15 ENSDART00000172335
ENSDART00000163162
cpne3
copine III
chr5_+_20366453 0.15 ENSDART00000193141
coro1ca
coronin, actin binding protein, 1Ca
chr24_+_25032340 0.15 ENSDART00000005845
mtmr6
myotubularin related protein 6
chr2_+_37140448 0.15 ENSDART00000045016
ENSDART00000142940
pex19
peroxisomal biogenesis factor 19
chr10_+_44700103 0.14 ENSDART00000165999
scarb1
scavenger receptor class B, member 1
chr17_+_44463230 0.14 ENSDART00000130311
naa30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr5_-_4245186 0.14 ENSDART00000145912
si:ch211-283g2.3
si:ch211-283g2.3
chr15_-_6966221 0.13 ENSDART00000165487
ENSDART00000027657
mrps22
mitochondrial ribosomal protein S22
chr20_+_28803977 0.13 ENSDART00000153351
ENSDART00000038149
fntb
farnesyltransferase, CAAX box, beta
chr4_-_12323228 0.11 ENSDART00000081089
il17ra1a
interleukin 17 receptor A1a
chr7_+_58751504 0.11 ENSDART00000024185
zgc:56231
zgc:56231
chr6_-_17052116 0.11 ENSDART00000156825
pimr45
Pim proto-oncogene, serine/threonine kinase, related 45
chr4_+_47174366 0.10 ENSDART00000170732
si:dkey-26m3.1
si:dkey-26m3.1
chr22_+_36914636 0.09 ENSDART00000150948
pimr205
Pim proto-oncogene, serine/threonine kinase, related 205
chr4_+_49322310 0.09 ENSDART00000184154
ENSDART00000167162
BX942819.1

chr17_+_6536152 0.08 ENSDART00000062952
ENSDART00000121789
slc5a6b
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr23_+_26017227 0.08 ENSDART00000002939
pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr6_-_16735402 0.07 ENSDART00000154216
pimr44
Pim proto-oncogene, serine/threonine kinase, related 44
chr10_-_43568239 0.07 ENSDART00000131731
ENSDART00000097433
ENSDART00000131309
mef2ca
myocyte enhancer factor 2ca
chr4_-_57572054 0.07 ENSDART00000158610
pimr168
Pim proto-oncogene, serine/threonine kinase, related 168
chr11_-_17964525 0.07 ENSDART00000018948
cishb
cytokine inducible SH2-containing protein b
chr8_-_46060685 0.06 ENSDART00000121902
pimr188
Pim proto-oncogene, serine/threonine kinase, related 188
chr6_+_39923052 0.06 ENSDART00000149019
itpr1a
inositol 1,4,5-trisphosphate receptor, type 1a
chr7_+_29890292 0.04 ENSDART00000170403
ENSDART00000168600
tln2a
talin 2a
chr20_-_54508650 0.03 ENSDART00000147642
CABZ01118770.1

chr7_-_13362590 0.03 ENSDART00000091616
sdhaf2
succinate dehydrogenase complex assembly factor 2
chr6_-_16804001 0.03 ENSDART00000155398
pimr40
Pim proto-oncogene, serine/threonine kinase, related 40
chr7_+_53254234 0.03 ENSDART00000169830
trip4
thyroid hormone receptor interactor 4
chr15_-_32383340 0.01 ENSDART00000185632
c4
complement component 4
chr3_+_35608385 0.00 ENSDART00000193219
ENSDART00000132703
traf7
TNF receptor-associated factor 7

Network of associatons between targets according to the STRING database.

First level regulatory network of stat5a+stat5b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.8 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.3 1.0 GO:0090248 hindbrain structural organization(GO:0021577) dorsal fin morphogenesis(GO:0035142) cell motility involved in somitogenic axis elongation(GO:0090247) cell migration involved in somitogenic axis elongation(GO:0090248)
0.3 1.3 GO:0018343 protein farnesylation(GO:0018343)
0.3 1.1 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.3 0.8 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 0.7 GO:0007635 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.2 1.0 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.2 1.5 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.2 1.2 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.4 GO:0039535 RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535)
0.1 0.4 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.1 0.7 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.4 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.1 1.6 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.9 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 1.1 GO:0051122 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.6 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1 0.8 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 1.6 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 2.3 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.1 0.7 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.8 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.9 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.9 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.5 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.5 GO:0032418 lysosome localization(GO:0032418)
0.0 0.1 GO:0036076 ligamentous ossification(GO:0036076)
0.0 1.1 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.1 GO:0051182 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:0060021 palate development(GO:0060021)
0.0 0.2 GO:0050482 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0042026 protein refolding(GO:0042026)
0.0 1.1 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 4.5 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 1.6 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.4 GO:0061512 protein localization to cilium(GO:0061512)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0031511 Mis6-Sim4 complex(GO:0031511)
0.3 1.3 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.2 1.5 GO:0030870 Mre11 complex(GO:0030870)
0.1 1.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.7 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 0.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 1.0 GO:0014704 intercalated disc(GO:0014704)
0.1 0.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.9 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 0.2 GO:0097541 axonemal basal plate(GO:0097541)
0.1 0.8 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.7 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.3 1.3 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.2 1.5 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.2 0.8 GO:0060182 apelin receptor activity(GO:0060182)
0.1 0.8 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.6 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 1.6 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.3 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 2.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 0.9 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.4 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.9 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.6 GO:0002039 p53 binding(GO:0002039)
0.0 0.7 GO:0015278 calcium-release channel activity(GO:0015278)
0.0 0.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.7 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.8 GO:0043022 ribosome binding(GO:0043022)
0.0 0.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 1.0 GO:0045296 cadherin binding(GO:0045296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.5 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.2 PID AURORA B PATHWAY Aurora B signaling
0.0 1.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.5 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 0.6 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 2.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.2 REACTOME KINESINS Genes involved in Kinesins
0.0 1.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.8 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis