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PRJEB1986: zebrafish developmental stages transcriptome

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Results for tal1

Z-value: 0.75

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Transcription factors associated with tal1

Gene Symbol Gene ID Gene Info
tal1
ENSDARG00000019930 T-cell acute lymphocytic leukemia 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tal1dr11_v1_chr22_+_16535575_165355750.861.8e-06Click!

Activity profile of tal1 motif

Sorted Z-values of tal1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_306533 1.81 ENSDART00000173437
poc1a
POC1 centriolar protein A
chr1_-_59571758 1.80 ENSDART00000193546
ENSDART00000167087
wfikkn1
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr21_-_217589 1.80 ENSDART00000185017
CZQB01146713.1

chr21_-_23331619 1.67 ENSDART00000007806
zbtb16a
zinc finger and BTB domain containing 16a
chr8_-_1051438 1.50 ENSDART00000067093
ENSDART00000170737
smyd1b
SET and MYND domain containing 1b
chr7_+_44715224 1.47 ENSDART00000184630
si:dkey-56m19.5
si:dkey-56m19.5
chr22_-_10541372 1.45 ENSDART00000179708
si:dkey-42i9.4
si:dkey-42i9.4
chr25_-_36261836 1.44 ENSDART00000179411
dus2
dihydrouridine synthase 2
chr25_-_36369057 1.42 ENSDART00000064400
si:ch211-113a14.24
si:ch211-113a14.24
chr15_-_4485828 1.41 ENSDART00000062868
tfdp2
transcription factor Dp-2
chr2_+_20866898 1.37 ENSDART00000150086
odr4
odr-4 GPCR localization factor homolog
chr6_+_40629066 1.33 ENSDART00000103757
slc6a11a
solute carrier family 6 (neurotransmitter transporter), member 11a
chr14_-_25928899 1.29 ENSDART00000143518
g3bp1
GTPase activating protein (SH3 domain) binding protein 1
chr1_+_277731 1.26 ENSDART00000133431
cenpe
centromere protein E
chr2_+_20793982 1.24 ENSDART00000014785
prg4a
proteoglycan 4a
chr14_-_22108718 1.24 ENSDART00000054410
med19a
mediator complex subunit 19a
chr14_-_9281232 1.16 ENSDART00000054693
asb12b
ankyrin repeat and SOCS box-containing 12b
chr7_+_5964296 1.16 ENSDART00000173380
si:dkey-23a13.17
si:dkey-23a13.17
chr24_-_9300160 1.14 ENSDART00000152378
tgif1
TGFB-induced factor homeobox 1
chr21_-_31210749 1.13 ENSDART00000185356
zgc:152891
zgc:152891
chr3_+_54581987 1.12 ENSDART00000018071
eif3g
eukaryotic translation initiation factor 3, subunit G
chr11_+_30296332 1.12 ENSDART00000192843
ugt1b7
UDP glucuronosyltransferase 1 family, polypeptide B7
chr10_+_16036573 1.10 ENSDART00000188757
lmnb1
lamin B1
chr7_+_2455344 1.09 ENSDART00000172942
si:dkey-125e8.4
si:dkey-125e8.4
chr7_+_26029672 1.07 ENSDART00000101126
alox12
arachidonate 12-lipoxygenase
chr17_-_2590222 1.05 ENSDART00000185711
CR759892.1

chr4_+_77943184 1.03 ENSDART00000159094
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr3_-_47235997 1.02 ENSDART00000047071
tmed1a
transmembrane p24 trafficking protein 1a
chr5_+_25762271 0.98 ENSDART00000181323
tmem2
transmembrane protein 2
chr12_-_48168135 0.98 ENSDART00000186624
pald1a
phosphatase domain containing, paladin 1a
chr23_-_19831739 0.98 ENSDART00000125066
haus7
HAUS augmin-like complex, subunit 7
chr17_-_28097760 0.97 ENSDART00000149861
kdm1a
lysine (K)-specific demethylase 1a
chr14_-_30390145 0.95 ENSDART00000045423
slc7a2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr17_-_10073926 0.94 ENSDART00000166081
ENSDART00000161574
zgc:109986
zgc:109986
chr24_-_6029314 0.94 ENSDART00000136155
ftr60
finTRIM family, member 60
chr7_+_6317866 0.93 ENSDART00000173397
si:ch211-220f21.3
si:ch211-220f21.3
chr1_-_53468160 0.93 ENSDART00000143349
zgc:66455
zgc:66455
chr1_+_292545 0.93 ENSDART00000148261
cenpe
centromere protein E
chr7_-_6346859 0.92 ENSDART00000172913
si:ch73-368j24.11
si:ch73-368j24.11
chr2_+_13694450 0.92 ENSDART00000077259
ENSDART00000189485
ebna1bp2
EBNA1 binding protein 2
chr4_+_38990661 0.92 ENSDART00000133258
si:dkey-122c11.1
si:dkey-122c11.1
chr17_+_132555 0.90 ENSDART00000158159
zgc:77287
zgc:77287
chr8_-_20118549 0.89 ENSDART00000132218
rfx2
regulatory factor X, 2 (influences HLA class II expression)
chr7_+_71683853 0.89 ENSDART00000163002
emilin2b
elastin microfibril interfacer 2b
chr10_+_8875195 0.87 ENSDART00000141045
itga2.3
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 3
chr18_-_46010 0.87 ENSDART00000052641
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr1_-_53880639 0.87 ENSDART00000010543
ltv1
LTV1 ribosome biogenesis factor
chr17_-_2578026 0.86 ENSDART00000065821
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr9_+_44994214 0.86 ENSDART00000141434
retsatl
retinol saturase (all-trans-retinol 13,14-reductase) like
chr14_+_9485070 0.86 ENSDART00000161486
ENSDART00000137274
st3gal5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr11_-_22372072 0.85 ENSDART00000065996
tmem183a
transmembrane protein 183A
chr3_-_29977495 0.84 ENSDART00000077111
hsd17b14
hydroxysteroid (17-beta) dehydrogenase 14
chr7_+_24049776 0.84 ENSDART00000166559
efs
embryonal Fyn-associated substrate
chr23_+_20513104 0.84 ENSDART00000079591
dpm1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr4_-_76488581 0.83 ENSDART00000174291
ftr51
finTRIM family, member 51
chr17_+_10074360 0.83 ENSDART00000166649
srp54
signal recognition particle 54
chr11_+_6136220 0.82 ENSDART00000082223
tax1bp3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr22_-_10541712 0.82 ENSDART00000013933
si:dkey-42i9.4
si:dkey-42i9.4
chr25_+_258883 0.82 ENSDART00000155256
zgc:92481
zgc:92481
chr8_+_46327350 0.81 ENSDART00000145618
si:dkey-75a21.2
si:dkey-75a21.2
chr2_-_20866758 0.80 ENSDART00000165374
tpra
translocated promoter region a, nuclear basket protein
chr16_+_54875530 0.79 ENSDART00000149795
nr0b2a
nuclear receptor subfamily 0, group B, member 2a
chr1_-_52494122 0.78 ENSDART00000131407
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr3_+_19665319 0.78 ENSDART00000007857
ENSDART00000193509
mettl2a
methyltransferase like 2A
chr4_-_2052687 0.77 ENSDART00000138291
ENSDART00000150844
cpsf6
cleavage and polyadenylation specific factor 6
chr21_+_53504 0.77 ENSDART00000170452
dmgdh
dimethylglycine dehydrogenase
chr16_+_42772678 0.75 ENSDART00000155575
si:ch211-135n15.2
si:ch211-135n15.2
chr19_-_24757231 0.75 ENSDART00000128177
si:dkey-154b15.1
si:dkey-154b15.1
chr17_-_2595736 0.75 ENSDART00000128797
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr4_-_67589158 0.75 ENSDART00000184361
BX088712.2

chr7_+_56577522 0.75 ENSDART00000149130
ENSDART00000149624
hp
haptoglobin
chr5_-_65000312 0.75 ENSDART00000192893
ANXA1 (1 of many)
zgc:110283
chr13_+_21674445 0.74 ENSDART00000100931
ENSDART00000078567
mtg1
mitochondrial ribosome-associated GTPase 1
chr19_-_1002959 0.74 ENSDART00000168138
ehmt2
euchromatic histone-lysine N-methyltransferase 2
chr25_+_27405738 0.74 ENSDART00000183266
ENSDART00000115139
pot1
protection of telomeres 1 homolog
chr2_+_49864219 0.73 ENSDART00000187744
rpl37
ribosomal protein L37
chr8_+_29742237 0.73 ENSDART00000133955
ENSDART00000020621
mapk4
mitogen-activated protein kinase 4
chr18_-_6862738 0.72 ENSDART00000192592
CT009745.1

chr4_-_48636872 0.72 ENSDART00000168605
znf1063
zinc finger protein 1063
chr6_-_51573975 0.71 ENSDART00000073865
rbl1
retinoblastoma-like 1 (p107)
chr4_+_64562090 0.71 ENSDART00000188810
si:ch211-223a21.3
si:ch211-223a21.3
chr18_+_16717764 0.71 ENSDART00000166849
eif4g2b
eukaryotic translation initiation factor 4, gamma 2b
chr8_+_39570615 0.69 ENSDART00000142557
lzts1
leucine zipper, putative tumor suppressor 1
chr1_+_22851261 0.68 ENSDART00000193925
gtf2e2
general transcription factor IIE, polypeptide 2, beta
chr20_+_53474963 0.68 ENSDART00000138976
bub1ba
BUB1 mitotic checkpoint serine/threonine kinase Ba
chr1_-_59141715 0.68 ENSDART00000164941
ENSDART00000138870
si:ch1073-110a20.1
si:ch1073-110a20.1
chr1_-_59232267 0.67 ENSDART00000169658
ENSDART00000163257
akap8l
A kinase (PRKA) anchor protein 8-like
chr4_-_52165969 0.67 ENSDART00000171130
si:dkeyp-44b5.4
si:dkeyp-44b5.4
chr17_-_2573021 0.67 ENSDART00000074181
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr10_-_24753715 0.67 ENSDART00000192401
ilk
integrin-linked kinase
chr13_+_40770628 0.67 ENSDART00000085846
nkx1.2la
NK1 transcription factor related 2-like,a
chr23_+_26079467 0.67 ENSDART00000129617
atp6ap1b
ATPase H+ transporting accessory protein 1b
chr7_-_30127082 0.66 ENSDART00000173749
alpk3b
alpha-kinase 3b
chr12_-_33789006 0.66 ENSDART00000034550
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr7_+_33132074 0.65 ENSDART00000073554
zgc:153219
zgc:153219
chr8_-_1255321 0.65 ENSDART00000149605
cdc14b
cell division cycle 14B
chr13_+_1131748 0.65 ENSDART00000054318
wdr92
WD repeat domain 92
chr1_+_49686408 0.65 ENSDART00000140824
si:ch211-149l1.2
si:ch211-149l1.2
chr19_-_48010490 0.64 ENSDART00000159938
FBXL19
zgc:158376
chr3_+_36671585 0.64 ENSDART00000159033
nde1
nudE neurodevelopment protein 1
chr5_-_68782641 0.64 ENSDART00000141699
mepce
methylphosphate capping enzyme
chr7_+_42935126 0.64 ENSDART00000157747
BX284696.1

chr14_+_9421510 0.63 ENSDART00000123652
hmgn6
high mobility group nucleosome binding domain 6
chr6_+_9241121 0.63 ENSDART00000064989
pimr70
Pim proto-oncogene, serine/threonine kinase, related 70
chr19_-_27588842 0.63 ENSDART00000121643
si:dkeyp-46h3.2
si:dkeyp-46h3.2
chr21_-_30026359 0.63 ENSDART00000153645
pwwp2a
PWWP domain containing 2A
chr17_-_2584423 0.63 ENSDART00000013506
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr4_-_43911462 0.62 ENSDART00000189056
ENSDART00000162441
ENSDART00000171367
znf1104
zinc finger protein 1104
chr7_+_56577906 0.62 ENSDART00000184023
hp
haptoglobin
chr1_+_513986 0.62 ENSDART00000109083
ENSDART00000081945
txnl4b
thioredoxin-like 4B
chr7_+_51795667 0.62 ENSDART00000174201
ENSDART00000073839
slc38a7
solute carrier family 38, member 7
chr3_-_32590164 0.61 ENSDART00000151151
tspan4b
tetraspanin 4b
chr22_-_29906764 0.60 ENSDART00000019786
smc3
structural maintenance of chromosomes 3
chr25_-_35142127 0.60 ENSDART00000049135
si:dkey-261m9.12
si:dkey-261m9.12
chr7_-_22790630 0.59 ENSDART00000173496
si:ch211-15b10.6
si:ch211-15b10.6
chr24_+_18714212 0.59 ENSDART00000171181
cspp1a
centrosome and spindle pole associated protein 1a
chr20_-_51547464 0.59 ENSDART00000099486
disp1
dispatched homolog 1 (Drosophila)
chr4_+_29206813 0.59 ENSDART00000131893
si:dkey-23a23.1
si:dkey-23a23.1
chr19_+_43978814 0.59 ENSDART00000102314
nkd3
naked cuticle homolog 3
chr19_-_21766461 0.58 ENSDART00000104279
znf516
zinc finger protein 516
chr15_-_15227541 0.58 ENSDART00000184787
rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr2_-_59345920 0.58 ENSDART00000134662
ftr37
finTRIM family, member 37
chr5_-_68333081 0.58 ENSDART00000168786
h1m
linker histone H1M
chr12_+_1609563 0.58 ENSDART00000163559
SLC39A11
solute carrier family 39 member 11
chr7_+_71535045 0.58 ENSDART00000047069
tyms
thymidylate synthetase
chr12_+_26632448 0.58 ENSDART00000185762
arhgap12b
Rho GTPase activating protein 12b
chr10_-_1788376 0.58 ENSDART00000123842
epb41l4a
erythrocyte membrane protein band 4.1 like 4A
chr11_+_25259058 0.57 ENSDART00000154109
tp53inp2
tumor protein p53 inducible nuclear protein 2
chr22_-_26353916 0.57 ENSDART00000077958
capn2b
calpain 2, (m/II) large subunit b
chr13_+_35474235 0.56 ENSDART00000181927
mkks
McKusick-Kaufman syndrome
chr6_+_9893554 0.56 ENSDART00000064979
pimr74
Pim proto-oncogene, serine/threonine kinase, related 74
chr1_-_55888970 0.56 ENSDART00000064194
asf1bb
anti-silencing function 1Bb histone chaperone
chr23_+_16807945 0.56 ENSDART00000080660
zgc:114081
zgc:114081
chr5_+_58520266 0.55 ENSDART00000108889
oafb
OAF homolog b (Drosophila)
chr20_-_15062606 0.55 ENSDART00000175585
ENSDART00000135212
prrc2c
proline-rich coiled-coil 2C
chr20_-_39391833 0.55 ENSDART00000135149
si:dkey-217m5.8
si:dkey-217m5.8
chr4_-_38033800 0.54 ENSDART00000159662
si:dkeyp-82b4.4
si:dkeyp-82b4.4
chr6_-_42377307 0.54 ENSDART00000129302
emc3
ER membrane protein complex subunit 3
chr2_-_59265521 0.54 ENSDART00000146341
ENSDART00000097799
ftr33
finTRIM family, member 33
chr19_-_10214264 0.54 ENSDART00000053300
ENSDART00000148225
znf865
zinc finger protein 865
chr23_-_36934944 0.54 ENSDART00000109976
ENSDART00000162179
acap3a
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3a
chr4_-_74466703 0.53 ENSDART00000174032
ENSDART00000189417
LO018124.1

chr13_-_42530656 0.53 ENSDART00000084327
btaf1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated
chr14_+_28432737 0.53 ENSDART00000026846
pin4
protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)
chr23_-_44848961 0.53 ENSDART00000136839
wu:fb72h05
wu:fb72h05
chr24_+_35827766 0.53 ENSDART00000144700
si:dkeyp-7a3.1
si:dkeyp-7a3.1
chr4_+_77709678 0.53 ENSDART00000036856
AL935186.1

chr2_-_5723786 0.52 ENSDART00000100924
cwc25
CWC25 spliceosome-associated protein homolog (S. cerevisiae)
chr7_-_5640822 0.52 ENSDART00000143767
BX000524.1

chr16_-_41990421 0.51 ENSDART00000055921
pycard
PYD and CARD domain containing
chr25_+_1732838 0.51 ENSDART00000159555
ENSDART00000168161
FBLN1
fibulin 1
chr15_-_14064302 0.51 ENSDART00000156384
BX927244.1

chr23_-_9925568 0.51 ENSDART00000081268
si:ch211-220i18.4
si:ch211-220i18.4
chr3_-_61377127 0.51 ENSDART00000155932
si:dkey-111k8.2
si:dkey-111k8.2
chr4_-_20208166 0.51 ENSDART00000066891
gsap
gamma-secretase activating protein
chr18_+_20482369 0.50 ENSDART00000100668
kbtbd4
kelch repeat and BTB (POZ) domain containing 4
chr2_-_59157790 0.50 ENSDART00000192303
ENSDART00000159362
ftr32
finTRIM family, member 32
chr5_+_41322783 0.49 ENSDART00000097546
arid3c
AT rich interactive domain 3C (BRIGHT-like)
chr4_+_13412030 0.49 ENSDART00000003694
cand1
cullin-associated and neddylation-dissociated 1
chr11_-_1392468 0.49 ENSDART00000004423
iars
isoleucyl-tRNA synthetase
chr5_+_338154 0.49 ENSDART00000191743
rnf170
ring finger protein 170
chr20_+_25225112 0.49 ENSDART00000153088
ENSDART00000127291
ENSDART00000130494
moxd1
monooxygenase, DBH-like 1
chr15_-_34051457 0.49 ENSDART00000189764
VWDE
si:dkey-30e9.7
chr9_-_23747264 0.49 ENSDART00000141461
ENSDART00000010311
ndufa10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10
chr11_-_5953636 0.49 ENSDART00000140960
ENSDART00000123601
dda1
DET1 and DDB1 associated 1
chr15_+_5116179 0.48 ENSDART00000101937
pgm2l1
phosphoglucomutase 2-like 1
chr5_+_36895860 0.48 ENSDART00000134493
srsf7a
serine/arginine-rich splicing factor 7a
chr6_-_29159888 0.48 ENSDART00000110288
zbtb11
zinc finger and BTB domain containing 11
chr14_-_36862745 0.48 ENSDART00000109293
rnf130
ring finger protein 130
chr9_-_7378566 0.48 ENSDART00000144003
slc23a3
solute carrier family 23, member 3
chr10_-_8294965 0.48 ENSDART00000167380
plpp1a
phospholipid phosphatase 1a
chr11_-_6970107 0.48 ENSDART00000171255
COMP
si:ch211-43f4.1
chr5_+_19933356 0.48 ENSDART00000088819
ankrd13a
ankyrin repeat domain 13A
chr1_-_29747702 0.47 ENSDART00000133225
ENSDART00000189670
spp2
secreted phosphoprotein 2
chr13_-_9024004 0.47 ENSDART00000169564
si:dkey-112g5.11
si:dkey-112g5.11
chr23_+_4260458 0.47 ENSDART00000103747
srsf6a
serine/arginine-rich splicing factor 6a
chr3_+_30500968 0.47 ENSDART00000103447
si:dkey-13n23.3
si:dkey-13n23.3
chr5_-_43805597 0.47 ENSDART00000127956
ENSDART00000028099
smn1
survival of motor neuron 1, telomeric
chr16_-_19568795 0.47 ENSDART00000185141
abcb5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr5_+_41477954 0.47 ENSDART00000185871
pias2
protein inhibitor of activated STAT, 2
chr6_+_27923054 0.46 ENSDART00000136833
ENSDART00000145533
cep63
centrosomal protein 63
chr1_+_2260407 0.46 ENSDART00000058876
kpnb3
karyopherin (importin) beta 3
chr5_+_65946222 0.46 ENSDART00000190969
ENSDART00000161578
mymk
myomaker, myoblast fusion factor
chr20_-_3310017 0.45 ENSDART00000099315
cebpz
CCAAT/enhancer binding protein (C/EBP), zeta
chr2_-_16565690 0.45 ENSDART00000022549
atp1b3a
ATPase Na+/K+ transporting subunit beta 3a
chr2_-_43739740 0.45 ENSDART00000113849
kif5ba
kinesin family member 5B, a
chr15_-_47857687 0.45 ENSDART00000098982
ENSDART00000151594
h3f3b.1
H3 histone, family 3B.1
chr23_+_578218 0.44 ENSDART00000055134
ogfr
opioid growth factor receptor
chr13_+_43639867 0.44 ENSDART00000042588
ENSDART00000074728
zfyve21
zinc finger, FYVE domain containing 21
chr7_-_17814118 0.43 ENSDART00000179688
ecsit
ECSIT signalling integrator
chr5_+_30392148 0.43 ENSDART00000086765
stk36
serine/threonine kinase 36 (fused homolog, Drosophila)
chr25_+_30460378 0.43 ENSDART00000016310
banp
BTG3 associated nuclear protein
chr9_+_33220342 0.43 ENSDART00000100893
ENSDART00000113451
si:ch211-125e6.13
si:ch211-125e6.13
chr19_-_10810006 0.43 ENSDART00000151157
si:dkey-3n22.9
si:dkey-3n22.9
chr15_+_23947932 0.42 ENSDART00000153951
myo18ab
myosin XVIIIAb
chr24_-_26399623 0.42 ENSDART00000112317
zgc:194621
zgc:194621
chr3_+_37649436 0.42 ENSDART00000075039
gosr2
golgi SNAP receptor complex member 2
chr9_+_33217243 0.42 ENSDART00000053061
si:ch211-125e6.12
si:ch211-125e6.12
chr20_+_46260580 0.42 ENSDART00000152872
taar14j
trace amine associated receptor 14j
chr19_+_40122160 0.41 ENSDART00000143966
si:ch211-173p18.3
si:ch211-173p18.3

Network of associatons between targets according to the STRING database.

First level regulatory network of tal1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.3 5.1 GO:0016584 nucleosome positioning(GO:0016584)
0.3 0.8 GO:2000008 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.3 0.8 GO:0046831 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833) messenger ribonucleoprotein complex assembly(GO:1990120)
0.2 0.6 GO:1900182 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.2 0.6 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.2 2.2 GO:0019372 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.2 2.9 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 0.8 GO:0090527 actin filament reorganization(GO:0090527)
0.2 0.8 GO:0019348 dolichol metabolic process(GO:0019348)
0.2 0.5 GO:0010265 SCF complex assembly(GO:0010265)
0.2 0.5 GO:0006589 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.2 0.9 GO:0097638 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.2 0.5 GO:0050787 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.1 0.7 GO:0051972 regulation of telomerase activity(GO:0051972)
0.1 1.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 1.5 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 0.7 GO:1901207 regulation of heart looping(GO:1901207)
0.1 0.7 GO:0008594 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.1 1.7 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.1 0.7 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.1 0.4 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.5 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.1 0.8 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.1 0.7 GO:0035989 tendon development(GO:0035989)
0.1 1.0 GO:0044854 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1 0.7 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.1 0.6 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.7 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.9 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.3 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.5 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.6 GO:0007100 mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299)
0.1 0.3 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.1 0.8 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.5 GO:1904396 regulation of neuromuscular junction development(GO:1904396)
0.1 0.4 GO:1904105 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.1 1.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.4 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 0.4 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 1.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.4 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.5 GO:0034205 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.1 0.3 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.1 0.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 1.0 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.3 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 1.0 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.4 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.6 GO:0042694 muscle cell fate specification(GO:0042694)
0.0 1.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.7 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.6 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.2 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.4 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.9 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.1 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.0 0.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.4 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0006747 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.0 0.2 GO:0040016 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) embryonic cleavage(GO:0040016)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.5 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.2 GO:0097499 protein localization to nonmotile primary cilium(GO:0097499)
0.0 2.9 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.1 GO:1903792 negative regulation of anion transport(GO:1903792)
0.0 0.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.5 GO:0046849 bone remodeling(GO:0046849)
0.0 0.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.2 GO:0048569 post-embryonic organ development(GO:0048569)
0.0 0.1 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.0 0.7 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.4 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 1.4 GO:0006400 tRNA modification(GO:0006400)
0.0 0.1 GO:0032530 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.0 1.5 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 0.5 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 1.0 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.4 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.8 GO:0008033 tRNA processing(GO:0008033)
0.0 0.2 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.5 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.5 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.6 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.8 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.8 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.9 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.8 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.6 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 0.2 GO:0070672 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.3 GO:0061512 protein localization to cilium(GO:0061512)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0042382 paraspeckles(GO:0042382)
0.1 0.7 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.5 GO:0061702 inflammasome complex(GO:0061702)
0.1 0.8 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 0.6 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.7 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 1.0 GO:0070652 HAUS complex(GO:0070652)
0.1 0.3 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 0.7 GO:0032797 SMN complex(GO:0032797)
0.1 0.6 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.9 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.4 GO:0070390 transcription export complex 2(GO:0070390)
0.1 1.5 GO:0031430 M band(GO:0031430)
0.1 0.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 5.8 GO:0000786 nucleosome(GO:0000786)
0.1 1.1 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.1 0.2 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.6 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.4 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.4 GO:0072487 MSL complex(GO:0072487)
0.0 0.4 GO:0016011 dystroglycan complex(GO:0016011)
0.0 1.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.8 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.7 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.9 GO:0030687 preribosome, large subunit precursor(GO:0030687) nuclear periphery(GO:0034399)
0.0 1.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.7 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.0 0.7 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 1.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.6 GO:0016605 PML body(GO:0016605)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 1.1 GO:0000922 spindle pole(GO:0000922)
0.0 2.4 GO:0000785 chromatin(GO:0000785)
0.0 1.2 GO:0016607 nuclear speck(GO:0016607)
0.0 0.5 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.0 0.5 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.3 0.9 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.3 2.9 GO:0035804 structural constituent of egg coat(GO:0035804)
0.3 0.8 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.3 5.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.3 1.5 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 0.6 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.2 0.8 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2 0.8 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.2 0.7 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.2 0.8 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.2 0.5 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 1.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.0 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.9 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 1.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.3 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.1 1.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 2.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.7 GO:0032977 membrane insertase activity(GO:0032977)
0.1 0.4 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 0.8 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.2 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 0.2 GO:0045545 syndecan binding(GO:0045545)
0.1 0.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.3 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.0 1.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 1.2 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.0 0.7 GO:0002039 p53 binding(GO:0002039)
0.0 0.9 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.5 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.7 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.0 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.0 0.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.7 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.9 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.9 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.6 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0043236 laminin binding(GO:0043236)
0.0 1.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.7 GO:0019843 rRNA binding(GO:0019843)
0.0 1.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 2.0 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:0015923 mannosidase activity(GO:0015923)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 2.8 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 2.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 2.2 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 PID ATM PATHWAY ATM pathway
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.9 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 0.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.0 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.6 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.3 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.3 REACTOME TRANSLATION Genes involved in Translation
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.3 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.7 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production