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PRJEB1986: zebrafish developmental stages transcriptome

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Results for tbp

Z-value: 6.41

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Transcription factors associated with tbp

Gene Symbol Gene ID Gene Info
tbp
ENSDARG00000014994 TATA box binding protein

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tbpdr11_v1_chr13_-_24396199_24396199-0.743.0e-04Click!

Activity profile of tbp motif

Sorted Z-values of tbp motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22240052 56.19 ENSDART00000111109
crygm2d9
crystallin, gamma M2d9
chr9_-_22232902 52.07 ENSDART00000101845
crygm2d5
crystallin, gamma M2d5
chr6_+_41181869 46.66 ENSDART00000002046
opn1mw1
opsin 1 (cone pigments), medium-wave-sensitive, 1
chr9_-_22245572 44.25 ENSDART00000114943
crygm2d4
crystallin, gamma M2d4
chr9_-_22299412 38.32 ENSDART00000139101
crygm2d21
crystallin, gamma M2d21
chr9_-_22158784 37.47 ENSDART00000167850
crygm2d14
crystallin, gamma M2d14
chr9_-_22213297 36.43 ENSDART00000110656
ENSDART00000133149
crygm2d20
crystallin, gamma M2d20
chr9_-_22135576 35.00 ENSDART00000101902
crygm2d8
crystallin, gamma M2d8
chr16_-_25085327 34.16 ENSDART00000077661
prss1
protease, serine 1
chr6_-_346084 33.93 ENSDART00000162599
pde6ha
phosphodiesterase 6H, cGMP-specific, cone, gamma, paralog a
chr9_-_22281854 33.46 ENSDART00000146319
crygm2d3
crystallin, gamma M2d3
chr9_-_22318511 33.17 ENSDART00000129295
crygm2d2
crystallin, gamma M2d2
chr11_+_25477643 33.17 ENSDART00000065941
opn1lw1
opsin 1 (cone pigments), long-wave-sensitive, 1
chr5_+_37837245 32.93 ENSDART00000171617
epd
ependymin
chr9_-_22117430 32.51 ENSDART00000101916
crygm2d15
crystallin, gamma M2d15
chr9_-_22129788 32.12 ENSDART00000124272
ENSDART00000175417
crygm2d8
crystallin, gamma M2d8
chr9_-_22135420 31.77 ENSDART00000184959
crygm2d8
crystallin, gamma M2d8
chr9_-_22272181 30.72 ENSDART00000113174
crygm2d7
crystallin, gamma M2d7
chr24_-_41312459 30.56 ENSDART00000041349
crygn2
crystallin, gamma N2
chr9_-_22158325 28.05 ENSDART00000114568
crygm2d16
crystallin, gamma M2d16
chr5_-_30615901 27.08 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr9_-_22182396 26.66 ENSDART00000101809
crygm2d6
crystallin, gamma M2d6
chr7_+_35068036 24.28 ENSDART00000022139
zgc:136461
zgc:136461
chr12_-_17712393 23.80 ENSDART00000143534
ENSDART00000010144
pvalb2
parvalbumin 2
chr9_-_22188117 23.55 ENSDART00000132890
crygm2d17
crystallin, gamma M2d17
chr21_+_30043054 23.22 ENSDART00000065448
fabp6
fatty acid binding protein 6, ileal (gastrotropin)
chr9_-_22339582 22.16 ENSDART00000134805
crygm2d1
crystallin, gamma M2d1
chr2_-_38000276 22.09 ENSDART00000034790
pcp4l1
Purkinje cell protein 4 like 1
chr11_+_24002503 20.85 ENSDART00000164702
chia.2
chitinase, acidic.2
chr24_+_3307857 19.73 ENSDART00000106527
gyg1b
glycogenin 1b
chr11_+_24001993 19.62 ENSDART00000168215
chia.2
chitinase, acidic.2
chr10_-_44027391 19.51 ENSDART00000145404
crybb1
crystallin, beta B1
chr9_-_22147567 19.49 ENSDART00000110941
crygm2d14
crystallin, gamma M2d14
chr19_-_3193912 19.27 ENSDART00000133159
si:ch211-133n4.6
si:ch211-133n4.6
chr9_+_22080122 18.99 ENSDART00000065956
ENSDART00000136014
crygm2e
crystallin, gamma M2e
chr25_+_8356707 18.75 ENSDART00000153708
muc5.1
mucin 5.1, oligomeric mucus/gel-forming
chr11_+_25472758 18.75 ENSDART00000011178
opn1sw2
opsin 1 (cone pigments), short-wave-sensitive 2
chr15_+_19682013 17.48 ENSDART00000127368
si:dkey-4p15.5
si:dkey-4p15.5
chr6_-_40755909 17.30 ENSDART00000026257
myhb
myosin, heavy chain b
chr17_+_27456804 16.65 ENSDART00000017756
ENSDART00000181461
ENSDART00000180178
ctsl.1
cathepsin L.1
chr8_+_48613040 16.01 ENSDART00000121432
nppa
natriuretic peptide A
chr5_-_33259079 15.78 ENSDART00000132223
ifitm1
interferon induced transmembrane protein 1
chr19_-_3193443 15.46 ENSDART00000179855
si:ch211-133n4.6
si:ch211-133n4.6
chr15_+_45643787 15.29 ENSDART00000055995
ENSDART00000157750
sagb
S-antigen; retina and pineal gland (arrestin) b
chr15_-_5815006 15.21 ENSDART00000102459
rbp2a
retinol binding protein 2a, cellular
chr6_-_40756138 15.17 ENSDART00000156295
myhb
myosin, heavy chain b
chr21_+_25226558 15.13 ENSDART00000168480
sycn.2
syncollin, tandem duplicate 2
chr3_+_33340939 14.71 ENSDART00000128786
pyya
peptide YYa
chr12_-_35988586 14.53 ENSDART00000157746
pde6gb
phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b
chr5_-_71722257 14.18 ENSDART00000013404
ak1
adenylate kinase 1
chr15_+_15390882 13.79 ENSDART00000062024
ca4b
carbonic anhydrase IV b
chr10_-_17745345 13.59 ENSDART00000132690
ENSDART00000135376
si:dkey-200l5.4
si:dkey-200l5.4
chr6_+_41186320 13.32 ENSDART00000025241
opn1mw2
opsin 1 (cone pigments), medium-wave-sensitive, 2
chr19_-_5345930 12.99 ENSDART00000066620
ENSDART00000151398
krtt1c19e
keratin type 1 c19e
chr2_-_1443692 12.46 ENSDART00000004533
rpe65a
retinal pigment epithelium-specific protein 65a
chr23_+_45579497 12.26 ENSDART00000110381
egr4
early growth response 4
chr22_-_263117 11.62 ENSDART00000158134
zgc:66156
zgc:66156
chr22_-_282498 11.53 ENSDART00000182766
CABZ01079178.1

chr5_+_9348284 11.30 ENSDART00000149417
tal2
T-cell acute lymphocytic leukemia 2
chr5_-_27867657 11.18 ENSDART00000112495
tcima
transcriptional and immune response regulator a
chr22_-_11626014 11.16 ENSDART00000063133
ENSDART00000160085
gcga
glucagon a
chr21_+_25216397 11.05 ENSDART00000130970
sycn.3
syncollin, tandem duplicate 3
chr25_-_18454016 10.96 ENSDART00000005877
cpa1
carboxypeptidase A1 (pancreatic)
chr1_-_22338521 10.92 ENSDART00000176849
si:ch73-380n15.2
si:ch73-380n15.2
chr10_-_24371312 10.81 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr10_+_17026870 10.80 ENSDART00000184529
ENSDART00000157480
CR855996.2

chr3_-_32818607 10.64 ENSDART00000075465
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr20_-_39273987 10.53 ENSDART00000127173
clu
clusterin
chr1_+_55137943 10.22 ENSDART00000138070
ENSDART00000150510
ENSDART00000133472
ENSDART00000136378
mb
myoglobin
chr21_-_28523548 10.08 ENSDART00000077910
epdl2
ependymin-like 2
chr11_+_3575963 9.99 ENSDART00000077305
si:dkey-33m11.8
si:dkey-33m11.8
chr9_+_22017368 9.54 ENSDART00000023059
zgc:153846
zgc:153846
chr5_-_36837846 9.14 ENSDART00000032481
ckma
creatine kinase, muscle a
chr19_+_19976990 9.12 ENSDART00000052627
npvf
neuropeptide VF precursor
chr7_-_7823662 9.12 ENSDART00000167652
cxcl8b.3
chemokine (C-X-C motif) ligand 8b, duplicate 3
chr18_-_5527050 8.97 ENSDART00000145400
ENSDART00000132498
ENSDART00000146209
zgc:153317
zgc:153317
chr7_-_16562200 8.90 ENSDART00000169093
ENSDART00000173491
csrp3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr15_+_19681718 8.87 ENSDART00000164803
si:dkey-4p15.5
si:dkey-4p15.5
chr3_+_59051503 8.84 ENSDART00000160767
rasd4
rasd family member 4
chr6_+_39499623 8.84 ENSDART00000036057
si:ch211-173n18.3
si:ch211-173n18.3
chr25_+_8407892 8.81 ENSDART00000153536
muc5.2
mucin 5.2
chr7_-_73851280 8.81 ENSDART00000190053
FP236812.3

chr3_-_57425961 8.72 ENSDART00000033716
socs3a
suppressor of cytokine signaling 3a
chr14_-_33872092 8.72 ENSDART00000111903
si:ch73-335m24.2
si:ch73-335m24.2
chr14_-_11507211 8.70 ENSDART00000186873
ENSDART00000109181
ENSDART00000186166
ENSDART00000186986
zgc:174917
zgc:174917
chr6_+_3934738 8.67 ENSDART00000159673
dync1i2b
dynein, cytoplasmic 1, intermediate chain 2b
chr23_-_17429775 8.66 ENSDART00000043076
ppdpfb
pancreatic progenitor cell differentiation and proliferation factor b
chr9_+_1139378 8.65 ENSDART00000170033
slc15a1a
solute carrier family 15 (oligopeptide transporter), member 1a
chr10_-_39321367 8.63 ENSDART00000129647
smtlb
somatolactin beta
chr25_+_30298377 8.55 ENSDART00000153622
C11orf96
chromosome 11 open reading frame 96
chr1_+_29096881 8.45 ENSDART00000075539
cryaa
crystallin, alpha A
chr10_-_22845485 8.34 ENSDART00000079454
vamp2
vesicle-associated membrane protein 2
chr22_+_18530395 8.21 ENSDART00000105415
ENSDART00000183958
si:ch211-212d10.1
si:ch211-212d10.1
chr4_+_17336557 8.07 ENSDART00000111650
pmch
pro-melanin-concentrating hormone
chr2_+_15100742 8.05 ENSDART00000027171
f3b
coagulation factor IIIb
chr17_+_9308425 8.04 ENSDART00000188283
ENSDART00000183311
NPAS3
neuronal PAS domain protein 3
chr16_-_44349845 7.96 ENSDART00000170932
rims2a
regulating synaptic membrane exocytosis 2a
chr3_+_26135502 7.81 ENSDART00000146979
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr8_+_48609521 7.73 ENSDART00000060765
nppb
natriuretic peptide B
chr13_-_2215213 7.70 ENSDART00000129773
mlip
muscular LMNA-interacting protein
chr12_-_3903886 7.61 ENSDART00000184214
ENSDART00000041082
gdpd3b
glycerophosphodiester phosphodiesterase domain containing 3b
chr10_-_5058823 7.60 ENSDART00000139825
tmem150c
transmembrane protein 150C
chr20_+_27020201 7.57 ENSDART00000126919
ENSDART00000016014
chga
chromogranin A
chr21_-_25685739 7.41 ENSDART00000129619
ENSDART00000101205
phkg1b
phosphorylase kinase, gamma 1b (muscle)
chr1_+_1599979 7.39 ENSDART00000097626
urp2
urotensin II-related peptide
chr10_+_17776981 7.38 ENSDART00000141693
ccl19b
chemokine (C-C motif) ligand 19b
chr23_-_35082494 7.33 ENSDART00000189809
BX294434.1

chr18_+_14342326 7.22 ENSDART00000181013
ENSDART00000138372
si:dkey-246g23.2
si:dkey-246g23.2
chr14_-_2206476 7.04 ENSDART00000081870
pcdh2ab6
protocadherin 2 alpha b 6
chr3_+_15505275 6.75 ENSDART00000141714
nupr1
nuclear protein 1
chr11_+_34235372 6.72 ENSDART00000063150
fam43a
family with sequence similarity 43, member A
chr11_+_42478184 6.57 ENSDART00000089963
zgc:110286
zgc:110286
chr3_-_59472422 6.52 ENSDART00000100327
nptx1l
neuronal pentraxin 1 like
chr24_+_37688729 6.47 ENSDART00000137017
h3f3d
H3 histone, family 3D
chr8_-_6877390 6.47 ENSDART00000170883
ENSDART00000005321
neflb
neurofilament, light polypeptide b
chr22_+_5752257 6.30 ENSDART00000143052
cox14
COX14 cytochrome c oxidase assembly factor
chr21_+_7823146 6.25 ENSDART00000030579
crhbp
corticotropin releasing hormone binding protein
chr9_-_35334642 6.23 ENSDART00000157195
ncam2
neural cell adhesion molecule 2
chr11_-_45152702 6.04 ENSDART00000168066
afmid
arylformamidase
chr22_-_294700 6.03 ENSDART00000189179
CABZ01079179.1

chr14_-_11430566 5.91 ENSDART00000137154
ENSDART00000091158
irg1l
immunoresponsive gene 1, like
chr17_-_37214196 5.85 ENSDART00000128715
kif3cb
kinesin family member 3Cb
chr16_+_20161805 5.80 ENSDART00000192146
c16h2orf66
chromosome 16 C2orf66 homolog
chr2_-_6482240 5.75 ENSDART00000132623
rgs13
regulator of G protein signaling 13
chr14_-_46442459 5.75 ENSDART00000158770
fgfbp1b
fibroblast growth factor binding protein 1b
chr10_-_43964028 5.73 ENSDART00000009134
ENSDART00000133450
sept5b
septin 5b
chr13_+_38520927 5.72 ENSDART00000137299
ENSDART00000111080
adgrb3
adhesion G protein-coupled receptor B3
chr11_+_43403525 5.71 ENSDART00000180683
vipb
vasoactive intestinal peptide b
chr12_+_39034541 5.64 ENSDART00000182502
ENSDART00000169813
si:dkey-239b22.2
si:dkey-239b22.2
chr5_-_32274383 5.51 ENSDART00000122889
myhz1.3
myosin, heavy polypeptide 1.3, skeletal muscle
chr20_+_42668875 5.47 ENSDART00000048890
slc22a2
solute carrier family 22 (organic cation transporter), member 2
chr24_-_5786759 5.37 ENSDART00000152069
chst2b
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2b
chr4_-_4780667 5.35 ENSDART00000133973
si:ch211-258f14.2
si:ch211-258f14.2
chr10_+_38593645 5.35 ENSDART00000011573
mmp13a
matrix metallopeptidase 13a
chr2_+_24507597 5.28 ENSDART00000133109
rps28
ribosomal protein S28
chr3_-_36606884 5.28 ENSDART00000172003
si:dkeyp-72e1.6
si:dkeyp-72e1.6
chr3_+_49074008 5.18 ENSDART00000168864
zgc:112146
zgc:112146
chr7_-_66137065 5.17 ENSDART00000145843
pth1b
parathyroid hormone 1b
chr11_-_24016761 5.16 ENSDART00000153601
ENSDART00000067817
ENSDART00000170531
chia.3
chitinase, acidic.3
chr6_+_11249706 5.07 ENSDART00000186547
ENSDART00000193287
atg9a
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr11_-_40030139 5.06 ENSDART00000021916
uts2b
urotensin 2, beta
chr4_+_842010 5.06 ENSDART00000067461
si:ch211-152c2.3
si:ch211-152c2.3
chr9_-_22355391 5.03 ENSDART00000009115
crygm3
crystallin, gamma M3
chr15_-_44601331 4.99 ENSDART00000161514
zgc:165508
zgc:165508
chr6_+_11250033 4.99 ENSDART00000065411
ENSDART00000132677
atg9a
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr7_+_29951997 4.97 ENSDART00000173453
tpma
alpha-tropomyosin
chr13_-_20381485 4.89 ENSDART00000131351
si:ch211-270n8.1
si:ch211-270n8.1
chr6_+_39493864 4.87 ENSDART00000086263
mettl7a
methyltransferase like 7A
chr14_-_2036604 4.83 ENSDART00000192446
BX005294.2

chr5_-_13685047 4.75 ENSDART00000018351
zgc:65851
zgc:65851
chr4_+_1146346 4.70 ENSDART00000166467
chrm2a
cholinergic receptor, muscarinic 2a
chr21_+_25221940 4.64 ENSDART00000108972
sycn.1
syncollin, tandem duplicate 1
chr22_+_7480465 4.62 ENSDART00000034545
CELA1 (1 of many)
zgc:92745
chr6_-_54180699 4.61 ENSDART00000045901
rps10
ribosomal protein S10
chr23_+_27675581 4.55 ENSDART00000127198
rps26
ribosomal protein S26
chr12_-_29624638 4.54 ENSDART00000126744
nrg3b
neuregulin 3b
chr9_-_52386733 4.53 ENSDART00000171721
dap1b
death associated protein 1b
chr23_-_35347714 4.50 ENSDART00000161770
ENSDART00000165615
cpne9
copine family member IX
chr24_+_37598441 4.49 ENSDART00000125145
rhbdl1
rhomboid, veinlet-like 1 (Drosophila)
chr12_+_22607761 4.42 ENSDART00000153112
si:dkey-219e21.2
si:dkey-219e21.2
chr8_-_31369161 4.42 ENSDART00000019937
gadd45ga
growth arrest and DNA-damage-inducible, gamma a
chr3_-_60401826 4.32 ENSDART00000144030
ENSDART00000160821
si:ch211-214b16.4
si:ch211-214b16.4
chr5_+_4366431 4.14 ENSDART00000168560
ENSDART00000149185
sat1a.2
spermidine/spermine N1-acetyltransferase 1a, duplicate 2
chr2_+_24507770 4.13 ENSDART00000154802
ENSDART00000052063
rps28
ribosomal protein S28
chr9_+_31075896 4.13 ENSDART00000188042
clybl
citrate lyase beta like
chr13_+_23176330 4.05 ENSDART00000168351
sorbs1
sorbin and SH3 domain containing 1
chr17_+_14711765 3.98 ENSDART00000012889
cx28.6
connexin 28.6
chr4_-_4780510 3.95 ENSDART00000109609
si:ch211-258f14.2
si:ch211-258f14.2
chr7_+_5906327 3.94 ENSDART00000173160
zgc:112234
zgc:112234
chr2_-_53500424 3.94 ENSDART00000037557
admp
anti-dorsalizing morphogenic protein
chr5_+_21181047 3.91 ENSDART00000088506
arhgap25
Rho GTPase activating protein 25
chr17_-_29312506 3.86 ENSDART00000133668
tecpr2
tectonin beta-propeller repeat containing 2
chr20_-_36393555 3.77 ENSDART00000153421
si:dkey-1j5.4
si:dkey-1j5.4
chr22_-_21392748 3.61 ENSDART00000144648
ankrd24
ankyrin repeat domain 24
chr5_-_26181863 3.60 ENSDART00000098500
ccdc125
coiled-coil domain containing 125
chr17_-_50234004 3.60 ENSDART00000058706
fosaa
v-fos FBJ murine osteosarcoma viral oncogene homolog Aa
chr13_+_35745572 3.59 ENSDART00000159690
gpr75
G protein-coupled receptor 75
chr15_-_4967302 3.59 ENSDART00000101992
lipt2
lipoyl(octanoyl) transferase 2
chr10_+_6010570 3.58 ENSDART00000190025
ENSDART00000163680
hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr24_+_26402110 3.54 ENSDART00000133684
si:ch211-230g15.5
si:ch211-230g15.5
chr17_-_35361322 3.50 ENSDART00000019617
rsad2
radical S-adenosyl methionine domain containing 2
chr18_+_17534627 3.48 ENSDART00000061007
mt2
metallothionein 2
chr2_+_35603637 3.47 ENSDART00000147278
plk3
polo-like kinase 3 (Drosophila)
chr2_-_7431590 3.39 ENSDART00000185699
asip2b
agouti signaling protein, nonagouti homolog (mouse) 2b
chr2_-_42091926 3.39 ENSDART00000142663
si:dkey-97a13.12
si:dkey-97a13.12
chr3_+_5575313 3.39 ENSDART00000134693
ENSDART00000101807
si:ch211-106h11.3
si:ch211-106h11.3
chr15_+_1134870 3.36 ENSDART00000155392
p2ry13
purinergic receptor P2Y13
chr2_-_30182353 3.28 ENSDART00000019149
rpl7
ribosomal protein L7
chr9_+_42269059 3.23 ENSDART00000113435
si:dkey-10c21.1
si:dkey-10c21.1
chr24_-_31425799 3.17 ENSDART00000157998
cngb3.1
cyclic nucleotide gated channel beta 3, tandem duplicate 1
chr6_+_11250316 3.14 ENSDART00000137122
atg9a
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr4_-_20485508 3.13 ENSDART00000183276
ENSDART00000023337
napepld
N-acyl phosphatidylethanolamine phospholipase D
chr10_+_44924684 3.04 ENSDART00000181360
ENSDART00000170418
ENSDART00000170327
sec14l7
SEC14-like lipid binding 7
chr5_-_60885935 2.96 ENSDART00000128350
rad51d
RAD51 paralog D
chr20_+_35438300 2.95 ENSDART00000102504
ENSDART00000153249
tdrd6
tudor domain containing 6
chr10_-_24318538 2.94 ENSDART00000109549
ENSDART00000190656
inpp5kb
inositol polyphosphate-5-phosphatase Kb
chr19_+_32257472 2.92 ENSDART00000186471
atxn1a
ataxin 1a
chr10_+_42374957 2.85 ENSDART00000147926
COX5B
zgc:86599
chr6_-_23619428 2.82 ENSDART00000053126
aanat1
arylalkylamine N-acetyltransferase 1
chr4_+_75314247 2.81 ENSDART00000162365
CABZ01041913.1

Network of associatons between targets according to the STRING database.

First level regulatory network of tbp

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.1 48.5 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
7.9 23.7 GO:1905072 cardiac jelly development(GO:1905072)
4.9 651.8 GO:0002088 lens development in camera-type eye(GO:0002088)
4.7 18.8 GO:0044060 regulation of endocrine process(GO:0044060) endocrine hormone secretion(GO:0060986)
4.1 45.6 GO:0006032 chitin catabolic process(GO:0006032)
3.8 7.6 GO:0046888 negative regulation of hormone secretion(GO:0046888)
3.1 12.5 GO:1901825 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
2.3 111.9 GO:0018298 protein-chromophore linkage(GO:0018298)
2.2 8.9 GO:0035994 response to muscle stretch(GO:0035994)
2.0 14.2 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
2.0 7.8 GO:0031448 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
1.8 5.5 GO:0015695 organic cation transport(GO:0015695)
1.4 5.7 GO:0007620 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
1.3 13.2 GO:0044805 late nucleophagy(GO:0044805)
1.3 3.9 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
1.3 15.3 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
1.2 8.7 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
1.2 3.6 GO:0072592 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
1.2 3.6 GO:1902767 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
1.2 4.7 GO:0010459 cardiac conduction system development(GO:0003161) negative regulation of heart rate(GO:0010459)
1.1 5.7 GO:0016322 neuron remodeling(GO:0016322)
1.1 8.7 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
1.1 8.5 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
1.0 4.1 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
1.0 8.7 GO:0006857 oligopeptide transport(GO:0006857)
0.9 3.5 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.8 10.8 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.8 8.6 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.8 3.1 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.8 6.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.7 3.0 GO:0042148 strand invasion(GO:0042148)
0.7 5.9 GO:0090594 inflammatory response to wounding(GO:0090594)
0.7 31.5 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.6 10.1 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.6 14.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.6 2.4 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.6 8.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.5 10.9 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.5 10.2 GO:0014823 response to activity(GO:0014823)
0.4 4.2 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.4 2.4 GO:0015846 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.4 1.9 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.4 11.2 GO:0003323 type B pancreatic cell development(GO:0003323)
0.4 10.0 GO:0007631 feeding behavior(GO:0007631)
0.4 8.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.4 2.5 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.3 0.3 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.3 5.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.3 11.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.3 2.9 GO:0030719 P granule organization(GO:0030719)
0.3 3.5 GO:0051597 response to methylmercury(GO:0051597)
0.3 38.8 GO:0007160 cell-matrix adhesion(GO:0007160)
0.3 3.6 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.3 1.6 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.3 5.5 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.3 1.0 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.3 1.0 GO:0099563 modification of synaptic structure(GO:0099563)
0.2 1.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.2 2.7 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2 1.0 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.2 2.1 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.2 5.9 GO:0010507 negative regulation of autophagy(GO:0010507)
0.2 5.4 GO:0048246 macrophage chemotaxis(GO:0048246)
0.2 11.7 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.2 3.9 GO:0051058 negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.2 1.0 GO:0046677 response to antibiotic(GO:0046677)
0.2 4.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.2 1.2 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.2 0.3 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.2 1.0 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.2 9.3 GO:0006730 one-carbon metabolic process(GO:0006730)
0.2 11.9 GO:0008217 regulation of blood pressure(GO:0008217)
0.2 5.7 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.2 9.9 GO:0015914 phospholipid transport(GO:0015914)
0.2 1.9 GO:2000377 regulation of reactive oxygen species metabolic process(GO:2000377)
0.1 0.7 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.1 37.6 GO:0006887 exocytosis(GO:0006887)
0.1 0.5 GO:1903798 regulation of production of small RNA involved in gene silencing by RNA(GO:0070920) regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.1 8.0 GO:0007596 blood coagulation(GO:0007596)
0.1 2.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 5.6 GO:1990266 neutrophil migration(GO:1990266)
0.1 0.6 GO:0016559 peroxisome fission(GO:0016559)
0.1 1.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 1.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 6.5 GO:0021510 spinal cord development(GO:0021510)
0.1 2.5 GO:0051923 sulfation(GO:0051923)
0.1 0.8 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.1 1.6 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 8.7 GO:0010970 establishment of localization by movement along microtubule(GO:0010970)
0.1 8.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 0.7 GO:0006465 signal peptide processing(GO:0006465)
0.1 7.6 GO:0010506 regulation of autophagy(GO:0010506)
0.1 1.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 1.0 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 4.2 GO:0051607 defense response to virus(GO:0051607)
0.1 0.4 GO:0045299 otolith mineralization(GO:0045299)
0.1 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 2.4 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.8 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 3.3 GO:0061515 myeloid cell development(GO:0061515)
0.0 4.8 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.9 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 8.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 2.8 GO:0007623 circadian rhythm(GO:0007623)
0.0 2.8 GO:0007601 visual perception(GO:0007601)
0.0 2.4 GO:0006334 nucleosome assembly(GO:0006334)
0.0 4.3 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.2 GO:0001709 cell fate determination(GO:0001709)
0.0 31.3 GO:0006508 proteolysis(GO:0006508)
0.0 1.8 GO:0031101 fin regeneration(GO:0031101)
0.0 1.0 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 1.2 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.3 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.9 48.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
3.3 127.2 GO:0001750 photoreceptor outer segment(GO:0001750)
3.1 9.4 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
2.0 7.8 GO:0031673 H zone(GO:0031673)
1.8 18.1 GO:0042583 chromaffin granule(GO:0042583)
1.7 30.8 GO:0030667 secretory granule membrane(GO:0030667)
1.6 8.1 GO:0005883 neurofilament(GO:0005883)
1.0 2.9 GO:0033391 chromatoid body(GO:0033391)
1.0 5.7 GO:0043083 synaptic cleft(GO:0043083)
0.7 10.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.6 8.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.6 7.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.6 3.0 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.6 3.9 GO:0001891 phagocytic cup(GO:0001891)
0.5 13.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.4 50.7 GO:0016459 myosin complex(GO:0016459)
0.3 8.0 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.2 3.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 63.4 GO:0005764 lysosome(GO:0005764)
0.2 8.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 13.8 GO:0031225 anchored component of membrane(GO:0031225)
0.2 5.7 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.2 7.7 GO:0016605 PML body(GO:0016605)
0.2 0.7 GO:0005787 signal peptidase complex(GO:0005787)
0.2 10.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 2.3 GO:0048179 activin receptor complex(GO:0048179)
0.2 1.0 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.2 7.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 3.5 GO:0035102 PRC1 complex(GO:0035102)
0.1 5.7 GO:0043204 perikaryon(GO:0043204)
0.1 0.4 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 155.5 GO:0005615 extracellular space(GO:0005615)
0.1 81.6 GO:0005576 extracellular region(GO:0005576)
0.1 1.0 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.1 0.7 GO:0016011 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.1 2.5 GO:0005921 gap junction(GO:0005921)
0.1 0.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 5.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 10.5 GO:0005802 trans-Golgi network(GO:0005802)
0.1 8.1 GO:0005882 intermediate filament(GO:0005882)
0.1 0.6 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.0 GO:0043209 myelin sheath(GO:0043209)
0.1 4.3 GO:0005871 kinesin complex(GO:0005871)
0.0 4.3 GO:0005884 actin filament(GO:0005884)
0.0 4.2 GO:0030018 Z disc(GO:0030018)
0.0 2.4 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 1.3 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 4.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 10.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.8 GO:0001726 ruffle(GO:0001726)
0.0 0.4 GO:0008305 integrin complex(GO:0008305)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.0 661.2 GO:0005212 structural constituent of eye lens(GO:0005212)
4.1 45.6 GO:0004568 chitinase activity(GO:0004568)
3.9 23.2 GO:0032052 bile acid binding(GO:0032052)
3.7 48.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
3.6 10.9 GO:0042165 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
3.1 12.5 GO:0050251 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
3.1 15.4 GO:0031769 glucagon receptor binding(GO:0031769)
2.9 14.7 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
2.9 8.6 GO:0070186 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
2.8 8.5 GO:0004061 arylformamidase activity(GO:0004061)
2.3 111.9 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
2.3 9.1 GO:0005153 interleukin-8 receptor binding(GO:0005153)
1.9 7.7 GO:0005521 lamin binding(GO:0005521)
1.5 10.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
1.5 7.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
1.4 4.1 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
1.2 8.7 GO:0042936 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
1.2 3.6 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
1.2 3.6 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
1.1 4.5 GO:0070513 death domain binding(GO:0070513)
1.1 14.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.9 4.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.8 10.8 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.7 8.7 GO:0045503 dynein light chain binding(GO:0045503)
0.6 1.9 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.6 5.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.6 4.1 GO:0019809 spermidine binding(GO:0019809)
0.6 2.4 GO:0032896 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.5 13.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.5 2.9 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.5 10.2 GO:0005344 oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825)
0.5 7.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.5 5.5 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.4 11.2 GO:0005112 Notch binding(GO:0005112)
0.4 61.8 GO:0005179 hormone activity(GO:0005179)
0.4 4.7 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.4 1.2 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.4 11.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 2.4 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.4 10.5 GO:0051787 misfolded protein binding(GO:0051787)
0.4 7.6 GO:0004622 lysophospholipase activity(GO:0004622)
0.4 10.1 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 2.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.3 8.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 3.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.3 70.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.3 3.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.3 2.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.3 8.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 6.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 3.2 GO:0005223 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.2 1.0 GO:0004064 arylesterase activity(GO:0004064)
0.2 8.8 GO:0019003 GDP binding(GO:0019003)
0.2 4.0 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.2 30.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 55.1 GO:0003774 motor activity(GO:0003774)
0.2 4.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 8.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 3.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 2.1 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.2 6.3 GO:0017046 peptide hormone binding(GO:0017046)
0.2 1.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 2.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 1.6 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 8.0 GO:0044325 ion channel binding(GO:0044325)
0.1 24.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 18.4 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.1 0.9 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 4.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 8.0 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 2.5 GO:0022829 wide pore channel activity(GO:0022829)
0.1 1.4 GO:2001069 glycogen binding(GO:2001069)
0.1 0.8 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 14.2 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.1 1.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 2.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 76.1 GO:0005509 calcium ion binding(GO:0005509)
0.1 4.9 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.1 0.4 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 3.9 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.2 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 1.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 13.7 GO:0005198 structural molecule activity(GO:0005198)
0.0 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.3 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 1.9 GO:0004601 peroxidase activity(GO:0004601)
0.0 15.7 GO:0016757 transferase activity, transferring glycosyl groups(GO:0016757)
0.0 4.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 5.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.5 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.8 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 3.6 GO:0060090 binding, bridging(GO:0060090)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 1.0 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.1 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 12.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.4 8.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.3 14.4 PID AP1 PATHWAY AP-1 transcription factor network
0.2 10.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.2 32.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 5.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 0.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 3.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.5 PID SHP2 PATHWAY SHP2 signaling
0.1 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.5 PID P73PATHWAY p73 transcription factor network
0.0 1.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 34.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
3.9 23.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
2.8 8.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
2.7 5.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
2.2 13.3 REACTOME OPSINS Genes involved in Opsins
1.0 15.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.8 16.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.7 14.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.7 8.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.4 4.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.4 7.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.4 18.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3 3.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.2 5.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 4.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 10.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 9.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 7.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 0.9 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1 1.6 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 2.5 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.1 3.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 2.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 3.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 2.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis