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PRJEB1986: zebrafish developmental stages transcriptome

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Results for tbx3a+tbx3b

Z-value: 0.94

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Transcription factors associated with tbx3a+tbx3b

Gene Symbol Gene ID Gene Info
tbx3a
ENSDARG00000002216 T-box transcription factor 3a
tbx3b
ENSDARG00000061509 T-box transcription factor 3b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tbx3bdr11_v1_chr5_+_26913120_269131200.862.1e-06Click!
tbx3adr11_v1_chr5_-_72324371_723243710.634.1e-03Click!

Activity profile of tbx3a+tbx3b motif

Sorted Z-values of tbx3a+tbx3b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_26532167 3.53 ENSDART00000061914
mthfd1l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr12_+_27141140 3.40 ENSDART00000136415
hoxb1b
homeobox B1b
chr11_-_23219367 3.03 ENSDART00000003646
optc
opticin
chr18_+_37272568 2.46 ENSDART00000132749
tmem123
transmembrane protein 123
chr3_+_37790351 2.41 ENSDART00000151506
si:dkey-260c8.8
si:dkey-260c8.8
chr19_+_7424347 2.33 ENSDART00000004622
sf3b4
splicing factor 3b, subunit 4
chr4_+_15006217 2.00 ENSDART00000090837
zc3hc1
zinc finger, C3HC-type containing 1
chr4_+_14981854 1.80 ENSDART00000067046
cax1
cation/H+ exchanger protein 1
chr1_+_25650917 1.72 ENSDART00000054235
plrg1
pleiotropic regulator 1
chr21_+_21611867 1.53 ENSDART00000189148
b9d2
B9 domain containing 2
chr5_+_29803380 1.50 ENSDART00000005263
ENSDART00000137558
ENSDART00000146963
ENSDART00000134900
usf1l
upstream transcription factor 1, like
chr13_-_11984867 1.49 ENSDART00000157538
npm3
nucleophosmin/nucleoplasmin, 3
chr19_-_18127629 1.46 ENSDART00000187722
snx10a
sorting nexin 10a
chr23_-_20345473 1.45 ENSDART00000140935
si:rp71-17i16.6
si:rp71-17i16.6
chr18_-_40913294 1.43 ENSDART00000059196
ENSDART00000098878
polr2i
polymerase (RNA) II (DNA directed) polypeptide I
chr14_+_3516567 1.43 ENSDART00000171153
ENSDART00000158416
fnta
farnesyltransferase, CAAX box, alpha
chr5_+_69278089 1.43 ENSDART00000136656
selenom
selenoprotein M
chr15_-_41677689 1.40 ENSDART00000187063
spsb4b
splA/ryanodine receptor domain and SOCS box containing 4b
chr1_+_218524 1.39 ENSDART00000109529
tmco3
transmembrane and coiled-coil domains 3
chr17_+_24604373 1.33 ENSDART00000082193
zmpste24
zinc metallopeptidase, STE24 homolog
chr7_+_29163762 1.33 ENSDART00000173762
slc38a8b
solute carrier family 38, member 8b
chr19_-_18127808 1.33 ENSDART00000108627
snx10a
sorting nexin 10a
chr4_-_5775507 1.31 ENSDART00000021753
ccnc
cyclin C
chr8_-_46897734 1.31 ENSDART00000138125
hes2.2
hes family bHLH transcription factor 2, tandem duplicate 2
chr23_-_19831739 1.31 ENSDART00000125066
haus7
HAUS augmin-like complex, subunit 7
chr2_-_37103622 1.29 ENSDART00000137849
zgc:101744
zgc:101744
chr11_+_11271959 1.28 ENSDART00000190678
ptp4a1
protein tyrosine phosphatase type IVA, member 1
chr12_+_31537604 1.27 ENSDART00000153340
si:ch73-205h11.1
si:ch73-205h11.1
chr23_+_2421689 1.26 ENSDART00000180200
tcp1
t-complex 1
chr17_-_27273296 1.22 ENSDART00000077087
id3
inhibitor of DNA binding 3
chr21_-_27195256 1.18 ENSDART00000133152
ENSDART00000065401
zgc:110782
zgc:110782
chr4_+_15899668 1.17 ENSDART00000101592
col7a1l
collagen type VII alpha 1-like
chr13_+_33304187 1.15 ENSDART00000075826
ENSDART00000145295
dcdc2b
doublecortin domain containing 2B
chr2_+_23482798 1.15 ENSDART00000187448
BX470197.1

chr12_-_26415499 1.15 ENSDART00000185779
synpo2lb
synaptopodin 2-like b
chr14_+_20911310 1.13 ENSDART00000160318
lygl2
lysozyme g-like 2
chr20_-_34164278 1.09 ENSDART00000153128
hmcn1
hemicentin 1
chr16_-_47301376 1.09 ENSDART00000169697
mios
missing oocyte, meiosis regulator, homolog (Drosophila)
chr13_-_51903150 1.02 ENSDART00000090644
mrpl2
mitochondrial ribosomal protein L2
chr6_-_55399214 1.01 ENSDART00000168367
ctsa
cathepsin A
chr8_+_15251448 1.00 ENSDART00000063717
zgc:171480
zgc:171480
chr2_+_42005475 0.97 ENSDART00000056461
gbp2
guanylate binding protein 2
chr16_-_14587332 0.97 ENSDART00000012479
dscc1
DNA replication and sister chromatid cohesion 1
chr21_+_21612214 0.94 ENSDART00000008099
b9d2
B9 domain containing 2
chr13_+_25486608 0.93 ENSDART00000057689
bag3
BCL2 associated athanogene 3
chr22_-_9157364 0.91 ENSDART00000182762
si:ch211-213a13.5
si:ch211-213a13.5
chr18_-_21748966 0.91 ENSDART00000181910
pskh1
protein serine kinase H1
chr5_-_17601759 0.89 ENSDART00000138387
si:ch211-130h14.6
si:ch211-130h14.6
chr2_-_21438492 0.88 ENSDART00000046098
plcd1b
phospholipase C, delta 1b
chr6_-_40651944 0.86 ENSDART00000187423
ppil1
peptidylprolyl isomerase (cyclophilin)-like 1
chr11_-_25461336 0.84 ENSDART00000014945
hcfc1a
host cell factor C1a
chr3_-_36690348 0.83 ENSDART00000192513
myh11b
myosin, heavy chain 11b, smooth muscle
chr17_-_50071748 0.82 ENSDART00000075188
zgc:113886
zgc:113886
chr8_-_50979047 0.80 ENSDART00000184788
ENSDART00000180906
zgc:91909
zgc:91909
chr7_+_17106160 0.78 ENSDART00000190048
ENSDART00000180004
ENSDART00000013409
prmt3
protein arginine methyltransferase 3
chr8_+_7854130 0.77 ENSDART00000165575
cxxc1a
CXXC finger protein 1a
chr16_+_23331633 0.76 ENSDART00000187455
krtcap2
keratinocyte associated protein 2
chr19_-_23674904 0.75 ENSDART00000187300
BX927234.2

chr4_-_60518031 0.74 ENSDART00000157489
si:dkey-211i20.4
si:dkey-211i20.4
chr5_+_29803702 0.74 ENSDART00000147569
usf1l
upstream transcription factor 1, like
chr25_-_27735290 0.73 ENSDART00000140663
zgc:153935
zgc:153935
chr9_+_30108641 0.73 ENSDART00000060174
jagn1a
jagunal homolog 1a
chr14_-_28052474 0.71 ENSDART00000172948
ENSDART00000135337
TSC22D3 (1 of many)
zgc:64189
si:ch211-220e11.3
zgc:64189
chr3_+_28831450 0.69 ENSDART00000055422
flr
fleer
chr10_+_26652859 0.68 ENSDART00000079174
htatsf1
HIV-1 Tat specific factor 1
chr16_+_32184485 0.67 ENSDART00000084009
zufsp
zinc finger with UFM1-specific peptidase domain
chr2_+_43895103 0.66 ENSDART00000007074
gbp3
guanylate binding protein 3
chr1_+_54901028 0.66 ENSDART00000137352
zfyve27
zinc finger, FYVE domain containing 27
chr5_-_10236599 0.64 ENSDART00000099834
si:ch73-42k18.1
si:ch73-42k18.1
chr16_-_41990421 0.64 ENSDART00000055921
pycard
PYD and CARD domain containing
chr21_+_22423286 0.63 ENSDART00000133190
capslb
calcyphosine-like b
chr19_-_10810006 0.62 ENSDART00000151157
si:dkey-3n22.9
si:dkey-3n22.9
chr21_+_7332963 0.61 ENSDART00000169834
AP3B1
adaptor related protein complex 3 beta 1 subunit
chr7_+_56472585 0.60 ENSDART00000135259
ENSDART00000073596
ist1
increased sodium tolerance 1 homolog (yeast)
chr22_-_5441893 0.60 ENSDART00000161421
zgc:194627
zgc:194627
chr4_+_77908076 0.53 ENSDART00000168811
si:zfos-2131b9.2
si:zfos-2131b9.2
chr21_-_33478164 0.53 ENSDART00000191542
si:ch73-42p12.2
si:ch73-42p12.2
chr12_+_18663154 0.52 ENSDART00000057918
si:ch211-147h1.4
si:ch211-147h1.4
chr4_+_77681389 0.52 ENSDART00000099727
gbp4
guanylate binding protein 4
chr13_+_30163515 0.52 ENSDART00000040926
eif4ebp2
eukaryotic translation initiation factor 4E binding protein 2
chr2_+_23677179 0.49 ENSDART00000153918
oxsr1a
oxidative stress responsive 1a
chr5_-_51148298 0.49 ENSDART00000042420
ccdc180
coiled-coil domain containing 180
chr14_+_23687678 0.48 ENSDART00000002469
hspa4b
heat shock protein 4b
chr3_-_33967767 0.47 ENSDART00000151493
ENSDART00000151160
ighv1-4
immunoglobulin heavy variable 1-4
chr18_-_7097403 0.47 ENSDART00000003748
cfap161
cilia and flagella associated protein 161
chr24_-_23942722 0.46 ENSDART00000080810
arxa
aristaless related homeobox a
chr17_+_8175998 0.43 ENSDART00000131200
myct1b
myc target 1b
chr10_-_15048781 0.42 ENSDART00000038401
ENSDART00000155674
si:ch211-95j8.2
si:ch211-95j8.2
chr12_+_20583552 0.41 ENSDART00000170035
arsg
arylsulfatase G
chr16_-_32184460 0.40 ENSDART00000102027
kpna5
karyopherin alpha 5 (importin alpha 6)
chr22_+_344763 0.40 ENSDART00000181934
CU914780.1

chr17_-_27200634 0.39 ENSDART00000185332
asap3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr22_+_9294336 0.39 ENSDART00000193694
si:ch211-250k18.7
si:ch211-250k18.7
chr17_-_53329704 0.38 ENSDART00000193895
exd1
exonuclease 3'-5' domain containing 1
chr22_+_2451732 0.37 ENSDART00000164419
znf1177
zinc finger protein 1177
chr7_-_33960170 0.37 ENSDART00000180766
skor1a
SKI family transcriptional corepressor 1a
chr25_-_27819838 0.36 ENSDART00000067106
lmod2a
leiomodin 2 (cardiac) a
chr6_-_1514767 0.35 ENSDART00000067586
chchd6b
coiled-coil-helix-coiled-coil-helix domain containing 6b
chr1_-_2453174 0.35 ENSDART00000055779
ENSDART00000152555
ggact.2
ggact.3
gamma-glutamylamine cyclotransferase, tandem duplicate 2
gamma-glutamylamine cyclotransferase, tandem duplicate 3
chr23_-_5683147 0.35 ENSDART00000102766
ENSDART00000067351
tnnt2a
troponin T type 2a (cardiac)
chr5_-_60159116 0.34 ENSDART00000147675
si:dkey-280e8.1
si:dkey-280e8.1
chr15_-_5178899 0.33 ENSDART00000132148
or126-4
odorant receptor, family E, subfamily 126, member 4
chr2_-_38992304 0.33 ENSDART00000114085
ENSDART00000146812
si:ch211-119o8.6
si:ch211-119o8.6
chr9_-_105135 0.33 ENSDART00000180126
FQ377903.3

chr22_+_567733 0.32 ENSDART00000171036
usp49
ubiquitin specific peptidase 49
chr25_-_15504559 0.32 ENSDART00000139294
BX323543.5

chr12_+_36109071 0.32 ENSDART00000171268
map2k6
mitogen-activated protein kinase kinase 6
chr7_-_3836635 0.30 ENSDART00000104350
si:dkey-88n24.8
si:dkey-88n24.8
chr5_+_69856153 0.29 ENSDART00000124128
ENSDART00000073663
ugt2a6
UDP glucuronosyltransferase 2 family, polypeptide A6
chr4_-_16001118 0.27 ENSDART00000041070
ENSDART00000125389
mest
mesoderm specific transcript
chr19_+_18493782 0.27 ENSDART00000160992
fkbp10a
FK506 binding protein 10a
chr21_+_25688388 0.26 ENSDART00000125709
bicdl2
bicaudal-D-related protein 2
chr9_-_29321625 0.25 ENSDART00000158689
ENSDART00000014047
ENSDART00000122602
pth2r
parathyroid hormone 2 receptor
chr25_-_15512819 0.25 ENSDART00000142684
si:dkeyp-67e1.2
si:dkeyp-67e1.2
chr7_-_3826794 0.25 ENSDART00000064229
ENSDART00000142138
si:dkey-88n24.10
si:dkey-88n24.10
chr19_+_9212031 0.24 ENSDART00000052930
ndufv1
NADH dehydrogenase (ubiquinone) flavoprotein 1
chr9_+_50001746 0.24 ENSDART00000058892
slc38a11
solute carrier family 38, member 11
chr18_+_32916351 0.23 ENSDART00000170387
ENSDART00000161553
olfcg2
olfactory receptor C family, g2
chr14_-_8903435 0.23 ENSDART00000160584
zgc:153681
zgc:153681
chr8_-_32894203 0.22 ENSDART00000147822
si:dkey-56i24.1
si:dkey-56i24.1
chr7_+_65121743 0.22 ENSDART00000108471
ipo7
importin 7
chr16_-_32672883 0.20 ENSDART00000124515
ENSDART00000190920
ENSDART00000188776
pnisr
PNN-interacting serine/arginine-rich protein
chr2_-_51611344 0.20 ENSDART00000158137
si:ch211-9d9.8
si:ch211-9d9.8
chr7_+_2236317 0.19 ENSDART00000075859
zgc:172065
zgc:172065
chr5_-_38197080 0.18 ENSDART00000140708
si:ch211-284e13.9
si:ch211-284e13.9
chr6_+_9793791 0.18 ENSDART00000149896
als2b
amyotrophic lateral sclerosis 2b (juvenile)
chr24_-_26479841 0.18 ENSDART00000079984
rpl22l1
ribosomal protein L22-like 1
chr4_+_51542447 0.17 ENSDART00000163814
si:dkey-165e24.1
si:dkey-165e24.1
chr12_+_20506197 0.17 ENSDART00000153010
si:zfos-754c12.2
si:zfos-754c12.2
chr8_+_26818446 0.17 ENSDART00000134987
ENSDART00000138835
si:ch211-156j16.1
si:ch211-156j16.1
chr8_-_25336589 0.17 ENSDART00000009682
atp5pb
ATP synthase peripheral stalk-membrane subunit b
chr4_+_62598975 0.17 ENSDART00000163548
si:ch211-79g12.2
si:ch211-79g12.2
chr20_-_874807 0.16 ENSDART00000020506
snx14
sorting nexin 14
chr7_-_3836896 0.16 ENSDART00000136227
si:dkey-88n24.8
si:dkey-88n24.8
chr24_-_25184553 0.14 ENSDART00000166917
plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr8_+_20918207 0.14 ENSDART00000144039
si:ch73-196i15.5
si:ch73-196i15.5
chr12_-_26491464 0.14 ENSDART00000153361
si:dkey-287g12.6
si:dkey-287g12.6
chr13_+_33462232 0.14 ENSDART00000177841
zgc:136302
zgc:136302
chr23_-_6722101 0.14 ENSDART00000157828
baz2a
bromodomain adjacent to zinc finger domain, 2A
chr16_-_50918908 0.14 ENSDART00000108744
CU855821.1

chr3_+_5297493 0.13 ENSDART00000138596
si:ch211-150d5.3
si:ch211-150d5.3
chr23_-_15090782 0.12 ENSDART00000133624
si:ch211-218g4.2
si:ch211-218g4.2
chr18_+_29145681 0.12 ENSDART00000089031
ENSDART00000193336
ppfibp2a
PTPRF interacting protein, binding protein 2a (liprin beta 2)
chr2_+_27403300 0.12 ENSDART00000099180
elovl8a
ELOVL fatty acid elongase 8a
chr7_+_13756374 0.10 ENSDART00000180808
rasl12
RAS-like, family 12
chr5_-_20491198 0.10 ENSDART00000183051
ENSDART00000144232
ficd
FIC domain containing
chr21_+_21655755 0.10 ENSDART00000079524
or125-8
odorant receptor, family E, subfamily 125, member 8
chr7_+_24889783 0.09 ENSDART00000005329
ENSDART00000159955
mark2b
MAP/microtubule affinity-regulating kinase 2b
chr4_-_36792144 0.07 ENSDART00000159147
si:dkeyp-87d1.1
si:dkeyp-87d1.1
chr18_+_17538165 0.06 ENSDART00000147839
nup93
nucleoporin 93
chr6_+_15250672 0.05 ENSDART00000155951
si:ch73-23l24.1
si:ch73-23l24.1
chr5_-_67783593 0.04 ENSDART00000010934
casr
calcium-sensing receptor
chr4_+_76431531 0.03 ENSDART00000174278
FP074874.1

chr15_+_23523337 0.03 ENSDART00000182306
ENSDART00000185545
ENSDART00000152517
si:dkey-182i3.9
si:dkey-182i3.9
chr6_+_9793495 0.02 ENSDART00000108524
als2b
amyotrophic lateral sclerosis 2b (juvenile)
chr3_-_48612078 0.01 ENSDART00000169923
ndel1b
nudE neurodevelopment protein 1-like 1b
chr4_+_332709 0.01 ENSDART00000067486
tulp4a
tubby like protein 4a
chr9_+_34334156 0.01 ENSDART00000144272
pou2f1b
POU class 2 homeobox 1b
chr11_+_44226200 0.01 ENSDART00000191417
gnb4b
guanine nucleotide binding protein (G protein), beta polypeptide 4b

Network of associatons between targets according to the STRING database.

First level regulatory network of tbx3a+tbx3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0070986 left/right axis specification(GO:0070986)
0.5 3.4 GO:0021570 rhombomere 4 development(GO:0021570) rhombomere 4 morphogenesis(GO:0021661)
0.4 1.3 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.4 1.7 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.4 3.2 GO:0036372 opsin transport(GO:0036372)
0.4 1.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.4 1.4 GO:0018343 protein farnesylation(GO:0018343)
0.3 1.0 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.3 0.9 GO:0010662 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.3 0.8 GO:0042543 protein N-linked glycosylation via arginine(GO:0042543)
0.2 0.7 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.2 3.5 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.2 1.3 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.2 1.4 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.5 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.1 2.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.5 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.7 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 0.3 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.1 0.3 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.1 1.2 GO:0035675 neuromast hair cell development(GO:0035675)
0.1 0.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 1.2 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.8 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.8 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 1.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 1.1 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 1.3 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.6 GO:0007032 endosome organization(GO:0007032)
0.0 1.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.1 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.6 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.2 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 1.3 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.3 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 0.4 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.1 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.3 GO:0010883 regulation of lipid storage(GO:0010883)
0.0 0.9 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.3 1.0 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 1.7 GO:0000974 Prp19 complex(GO:0000974)
0.2 0.7 GO:0032584 growth cone membrane(GO:0032584)
0.2 0.6 GO:0061702 inflammasome complex(GO:0061702)
0.2 2.5 GO:0036038 MKS complex(GO:0036038)
0.1 1.3 GO:0070652 HAUS complex(GO:0070652)
0.1 0.7 GO:0005879 axonemal microtubule(GO:0005879)
0.1 1.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 2.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 1.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.4 GO:1990923 PET complex(GO:1990923)
0.0 0.7 GO:0005686 U2 snRNP(GO:0005686)
0.0 2.0 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 1.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.3 GO:0016592 mediator complex(GO:0016592)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.7 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 1.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 2.5 GO:0010008 endosome membrane(GO:0010008)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.5 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.5 1.4 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.5 1.8 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.3 1.1 GO:0003796 lysozyme activity(GO:0003796)
0.2 0.7 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.2 0.7 GO:0043621 protein self-association(GO:0043621)
0.2 1.0 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 2.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.0 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 1.3 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.4 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.1 1.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.8 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.4 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 1.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 1.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 1.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.6 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.2 GO:0010181 NADH dehydrogenase (ubiquinone) activity(GO:0008137) FMN binding(GO:0010181) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.2 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 2.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 1.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 1.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 2.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis