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PRJEB1986: zebrafish developmental stages transcriptome

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Results for tfe3a+tfe3b

Z-value: 0.70

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Transcription factors associated with tfe3a+tfe3b

Gene Symbol Gene ID Gene Info
tfe3b
ENSDARG00000019457 transcription factor binding to IGHM enhancer 3b
tfe3a
ENSDARG00000098903 transcription factor binding to IGHM enhancer 3a
tfe3b
ENSDARG00000111231 transcription factor binding to IGHM enhancer 3b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tfe3bdr11_v1_chr11_+_25508129_255081290.607.0e-03Click!
tfe3adr11_v1_chr8_+_7778770_7778770-0.107.0e-01Click!

Activity profile of tfe3a+tfe3b motif

Sorted Z-values of tfe3a+tfe3b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_4540127 1.23 ENSDART00000043431
nup188
nucleoporin 188
chr18_+_26422124 1.13 ENSDART00000060245
ctsh
cathepsin H
chr17_+_32622933 1.12 ENSDART00000077418
ctsba
cathepsin Ba
chr1_+_10318089 1.11 ENSDART00000029774
pip4p1b
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1b
chr5_+_61475451 1.10 ENSDART00000163444
lrwd1
leucine-rich repeats and WD repeat domain containing 1
chr19_+_15440841 0.99 ENSDART00000182329
lin28a
lin-28 homolog A (C. elegans)
chr9_-_14273652 0.95 ENSDART00000135458
abcb6b
ATP-binding cassette, sub-family B (MDR/TAP), member 6b
chr19_+_15441022 0.92 ENSDART00000098970
ENSDART00000140276
lin28a
lin-28 homolog A (C. elegans)
chr2_-_24069331 0.89 ENSDART00000156972
ENSDART00000181691
ENSDART00000157041
slc12a7a
solute carrier family 12 (potassium/chloride transporter), member 7a
chr8_-_50981175 0.84 ENSDART00000004065
zgc:91909
zgc:91909
chr15_-_43625549 0.82 ENSDART00000168589
ctsc
cathepsin C
chr15_+_1199407 0.81 ENSDART00000163827
mfsd1
major facilitator superfamily domain containing 1
chr6_+_59944488 0.77 ENSDART00000161158
nufip1
nuclear fragile X mental retardation protein interacting protein 1
chr16_+_23960933 0.76 ENSDART00000146077
apoeb
apolipoprotein Eb
chr25_+_245438 0.75 ENSDART00000004689
zgc:92481
zgc:92481
chr16_-_9869056 0.75 ENSDART00000149312
ncalda
neurocalcin delta a
chr10_+_10210455 0.72 ENSDART00000144214
sh2d3ca
SH2 domain containing 3Ca
chr23_-_31913231 0.71 ENSDART00000146852
ENSDART00000085054
mtfr2
mitochondrial fission regulator 2
chr21_-_25601648 0.71 ENSDART00000042578
efemp2b
EGF containing fibulin extracellular matrix protein 2b
chr24_-_42072886 0.71 ENSDART00000171389
CABZ01095370.1

chr3_+_41922114 0.69 ENSDART00000138280
lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr9_+_36946340 0.69 ENSDART00000135281
si:dkey-3d4.3
si:dkey-3d4.3
chr8_-_36554675 0.67 ENSDART00000132804
ENSDART00000078746
ccdc157
coiled-coil domain containing 157
chr3_-_7296189 0.67 ENSDART00000148349
si:ch1073-186o8.3
si:ch1073-186o8.3
chr3_+_23768898 0.67 ENSDART00000110682
hoxb1a
homeobox B1a
chr18_-_1414760 0.65 ENSDART00000171881
PEPD
peptidase D
chr21_-_39058490 0.64 ENSDART00000114885
aldh3a2b
aldehyde dehydrogenase 3 family, member A2b
chr13_+_22295905 0.64 ENSDART00000180133
ENSDART00000181125
usp54a
ubiquitin specific peptidase 54a
chr3_-_49382896 0.64 ENSDART00000169115
si:ch73-167f10.1
si:ch73-167f10.1
chr13_+_13930263 0.63 ENSDART00000079154
rpia
ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase)
chr17_+_32623931 0.63 ENSDART00000144217
ctsba
cathepsin Ba
chr19_-_26823647 0.62 ENSDART00000002464
neu1
neuraminidase 1
chr19_-_1947403 0.61 ENSDART00000113951
ENSDART00000151293
ENSDART00000134074
znrf2a
zinc and ring finger 2a
chr22_+_30184039 0.60 ENSDART00000049075
add3a
adducin 3 (gamma) a
chr19_-_42503143 0.60 ENSDART00000007642
zgc:110239
zgc:110239
chr25_+_17405458 0.58 ENSDART00000186711
e2f4
E2F transcription factor 4
chr16_+_4654333 0.58 ENSDART00000167665
LIN28A
si:ch1073-284b18.2
chr8_-_20118549 0.57 ENSDART00000132218
rfx2
regulatory factor X, 2 (influences HLA class II expression)
chr7_+_1579236 0.57 ENSDART00000172830
supt16h
SPT16 homolog, facilitates chromatin remodeling subunit
chr1_+_45754868 0.56 ENSDART00000084512
pkn1a
protein kinase N1a
chr14_+_30543008 0.55 ENSDART00000145336
her5
hairy-related 5
chr25_+_258883 0.55 ENSDART00000155256
zgc:92481
zgc:92481
chr20_-_16849306 0.55 ENSDART00000131395
ENSDART00000027582
brms1lb
breast cancer metastasis-suppressor 1-like b
chr15_+_1534644 0.55 ENSDART00000130413
smc4
structural maintenance of chromosomes 4
chr7_+_65939098 0.54 ENSDART00000193599
RASSF10
Ras association domain family member 10
chr22_+_18349794 0.54 ENSDART00000186580
gatad2ab
GATA zinc finger domain containing 2Ab
chr24_-_12938922 0.53 ENSDART00000024084
pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr14_+_28442963 0.52 ENSDART00000186495
acsl4a
acyl-CoA synthetase long chain family member 4a
chr4_+_3358383 0.51 ENSDART00000075320
nampta
nicotinamide phosphoribosyltransferase a
chr12_-_2800809 0.51 ENSDART00000152682
ENSDART00000083784
ubtd1b
ubiquitin domain containing 1b
chr1_+_51827046 0.51 ENSDART00000052992
dand5
DAN domain family, member 5
chr17_-_114121 0.51 ENSDART00000172408
ENSDART00000157784
arhgap11a
Rho GTPase activating protein 11A
chr17_+_37215820 0.51 ENSDART00000104009
slc30a1b
solute carrier family 30 (zinc transporter), member 1b
chr21_-_19919918 0.50 ENSDART00000137307
ENSDART00000142523
ENSDART00000065670
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr21_-_45871866 0.50 ENSDART00000161716
larp1
La ribonucleoprotein domain family, member 1
chr21_-_9914745 0.49 ENSDART00000172124
arhgap24
Rho GTPase activating protein 24
chr25_-_36369057 0.49 ENSDART00000064400
si:ch211-113a14.24
si:ch211-113a14.24
chr2_-_27575803 0.49 ENSDART00000014568
urod
uroporphyrinogen decarboxylase
chr21_-_27362938 0.49 ENSDART00000131297
rin1a
Ras and Rab interactor 1a
chr19_+_40641338 0.48 ENSDART00000146468
vps50
VPS50 EARP/GARPII complex subunit
chr13_-_21650404 0.48 ENSDART00000078352
tspan14
tetraspanin 14
chr2_-_10877765 0.48 ENSDART00000100607
cdc7
cell division cycle 7 homolog (S. cerevisiae)
chr1_-_53504603 0.47 ENSDART00000162025
ENSDART00000100788
commd1
copper metabolism (Murr1) domain containing 1
chr5_+_32847238 0.47 ENSDART00000144364
si:ch211-208h16.4
si:ch211-208h16.4
chr23_+_33947874 0.47 ENSDART00000136104
si:ch211-148l7.4
si:ch211-148l7.4
chr8_-_16650595 0.47 ENSDART00000135319
osbpl9
oxysterol binding protein-like 9
chr19_-_22323695 0.46 ENSDART00000189355
si:ch73-196l6.5
si:ch73-196l6.5
chr12_+_7865470 0.46 ENSDART00000161683
BX548028.1

chr7_+_55518519 0.46 ENSDART00000098476
ENSDART00000149915
cdt1
chromatin licensing and DNA replication factor 1
chr21_+_8198652 0.46 ENSDART00000011096
nr6a1b
nuclear receptor subfamily 6, group A, member 1b
chr8_-_13735572 0.46 ENSDART00000139642
si:dkey-258f14.7
si:dkey-258f14.7
chr22_+_22302614 0.45 ENSDART00000049434
scamp4
secretory carrier membrane protein 4
chr2_+_29976419 0.45 ENSDART00000056748
en2b
engrailed homeobox 2b
chr21_-_4539899 0.45 ENSDART00000112460
dolk
dolichol kinase
chr13_-_18122333 0.45 ENSDART00000128748
washc2c
WASH complex subunit 2C
chr9_+_37152564 0.45 ENSDART00000189497
gli2a
GLI family zinc finger 2a
chr2_+_42005475 0.44 ENSDART00000056461
gbp2
guanylate binding protein 2
chr9_-_33063083 0.44 ENSDART00000048550
si:ch211-125e6.5
si:ch211-125e6.5
chr25_+_34749187 0.44 ENSDART00000141473
wwp2
WW domain containing E3 ubiquitin protein ligase 2
chr1_-_50791280 0.44 ENSDART00000181224
CABZ01031870.1

chr11_+_24819624 0.44 ENSDART00000155514
kdm5ba
lysine (K)-specific demethylase 5Ba
chr23_+_32028574 0.43 ENSDART00000145501
ENSDART00000143121
ENSDART00000111877
tpx2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr7_-_8961941 0.43 ENSDART00000111002
si:ch211-74f19.2
si:ch211-74f19.2
chr6_+_59832786 0.43 ENSDART00000154985
ENSDART00000102148
ddx3b
DEAD (Asp-Glu-Ala-Asp) box helicase 3b
chr2_-_43545342 0.43 ENSDART00000179796
CABZ01058721.1

chr7_+_24390939 0.42 ENSDART00000087494
ENSDART00000125463
haus3
HAUS augmin-like complex, subunit 3
chr3_-_29962345 0.42 ENSDART00000136819
bcat2
branched chain amino-acid transaminase 2, mitochondrial
chr23_+_44461493 0.42 ENSDART00000149854
si:ch1073-228j22.1
si:ch1073-228j22.1
chr16_+_23960744 0.42 ENSDART00000058965
apoeb
apolipoprotein Eb
chr25_+_17405201 0.42 ENSDART00000164349
e2f4
E2F transcription factor 4
chr23_+_42254960 0.42 ENSDART00000102980
zcchc11
zinc finger, CCHC domain containing 11
chr1_+_604127 0.42 ENSDART00000133165
jam2a
junctional adhesion molecule 2a
chr6_-_12644563 0.42 ENSDART00000153797
dock9b
dedicator of cytokinesis 9b
chr16_-_5143124 0.42 ENSDART00000131876
ENSDART00000060630
ttk
ttk protein kinase
chr3_-_32362872 0.41 ENSDART00000035545
ENSDART00000012630
prmt1
protein arginine methyltransferase 1
chr5_-_13167097 0.41 ENSDART00000149700
ENSDART00000030213
mapk1
mitogen-activated protein kinase 1
chr6_+_45918981 0.41 ENSDART00000149642
h6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr4_+_5341592 0.41 ENSDART00000123375
ENSDART00000067371
zgc:113263
zgc:113263
chr5_+_4564233 0.41 ENSDART00000193435
CABZ01058647.1

chr23_+_5565261 0.41 ENSDART00000059307
ENSDART00000169904
smpd2a
sphingomyelin phosphodiesterase 2a, neutral membrane (neutral sphingomyelinase)
chr1_+_19943803 0.41 ENSDART00000164661
apbb2b
amyloid beta (A4) precursor protein-binding, family B, member 2b
chr9_+_22782027 0.41 ENSDART00000090816
rif1
replication timing regulatory factor 1
chr13_-_4992395 0.40 ENSDART00000102651
nolc1
nucleolar and coiled-body phosphoprotein 1
chr10_+_39283985 0.40 ENSDART00000016464
dcps
decapping enzyme, scavenger
chr20_-_28698172 0.40 ENSDART00000190635
sipa1l1
signal-induced proliferation-associated 1 like 1
chr5_+_483965 0.40 ENSDART00000150007
tek
TEK tyrosine kinase, endothelial
chr24_-_21090447 0.40 ENSDART00000136507
ENSDART00000140786
ENSDART00000184841
qtrt2
queuine tRNA-ribosyltransferase accessory subunit 2
chr20_+_25904199 0.39 ENSDART00000016864
slc35f6
solute carrier family 35, member F6
chr25_+_31323978 0.39 ENSDART00000067030
lsp1
lymphocyte-specific protein 1
chr8_-_16725573 0.39 ENSDART00000049676
depdc1a
DEP domain containing 1a
chr12_-_19185865 0.39 ENSDART00000153343
zc3h7b
zinc finger CCCH-type containing 7B
chr7_+_46019780 0.38 ENSDART00000163991
ccne1
cyclin E1
chr17_+_24590177 0.38 ENSDART00000092941
rlf
rearranged L-myc fusion
chr9_-_55586151 0.38 ENSDART00000181886
arsh
arylsulfatase H
chr2_-_14793343 0.38 ENSDART00000132264
si:ch73-366i20.1
si:ch73-366i20.1
chr25_-_35599887 0.38 ENSDART00000153827
clpxb
caseinolytic mitochondrial matrix peptidase chaperone subunit b
chr11_-_4235811 0.38 ENSDART00000121716
si:ch211-236d3.4
si:ch211-236d3.4
chr19_+_167612 0.38 ENSDART00000169574
tatdn1
TatD DNase domain containing 1
chr19_+_19737214 0.38 ENSDART00000160283
ENSDART00000169017
hoxa11a
homeobox A11a
chr1_+_19764995 0.37 ENSDART00000138276
si:ch211-42i9.8
si:ch211-42i9.8
chr17_-_45370200 0.37 ENSDART00000186208
znf106a
zinc finger protein 106a
chr3_-_25420931 0.37 ENSDART00000109601
ENSDART00000182184
bptf
bromodomain PHD finger transcription factor
chr11_-_31276064 0.37 ENSDART00000141062
ENSDART00000004780
man2b1
mannosidase, alpha, class 2B, member 1
chr22_-_11606078 0.36 ENSDART00000146026
pcyt2
phosphate cytidylyltransferase 2, ethanolamine
chr10_+_45148005 0.36 ENSDART00000182501
ogdhb
oxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide)
chr1_-_8141135 0.36 ENSDART00000152295
FAM83G
si:dkeyp-9d4.4
chr19_-_2115040 0.36 ENSDART00000020497
snx13
sorting nexin 13
chr10_-_105100 0.36 ENSDART00000145716
ttc3
tetratricopeptide repeat domain 3
chr22_+_15979430 0.35 ENSDART00000189703
ENSDART00000192674
rc3h1a
ring finger and CCCH-type domains 1a
chr3_+_61391636 0.35 ENSDART00000126417
bri3
brain protein I3
chr20_+_53474963 0.35 ENSDART00000138976
bub1ba
BUB1 mitotic checkpoint serine/threonine kinase Ba
chr7_+_39410393 0.35 ENSDART00000158561
ENSDART00000185173
CT030188.1

chr21_+_6394929 0.35 ENSDART00000138600
si:ch211-225g23.1
si:ch211-225g23.1
chr6_+_59642695 0.35 ENSDART00000166373
ENSDART00000161030
R3HDM2
R3H domain containing 2
chr13_+_24662238 0.35 ENSDART00000014176
msx3
muscle segment homeobox 3
chr9_+_12847040 0.34 ENSDART00000181983
ENSDART00000047191
glb1l
galactosidase, beta 1-like
chr23_-_19051710 0.34 ENSDART00000111852
arfgef2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr22_+_9922301 0.34 ENSDART00000105924
blf
bloody fingers
chr18_-_16924221 0.34 ENSDART00000122102
wee1
WEE1 G2 checkpoint kinase
chr17_-_44440832 0.33 ENSDART00000148786
exoc5
exocyst complex component 5
chr1_-_25438934 0.33 ENSDART00000111686
fhdc1
FH2 domain containing 1
chr7_-_40993456 0.33 ENSDART00000031700
en2a
engrailed homeobox 2a
chr15_-_14038227 0.33 ENSDART00000139068
zgc:114130
zgc:114130
chr3_-_16784280 0.33 ENSDART00000137108
ENSDART00000137276
si:dkey-30j10.5
si:dkey-30j10.5
chr12_-_3778848 0.33 ENSDART00000152128
si:ch211-166g5.4
si:ch211-166g5.4
chr24_-_26854032 0.33 ENSDART00000087991
fndc3bb
fibronectin type III domain containing 3Bb
chr1_+_33322555 0.33 ENSDART00000113486
mxra5a
matrix-remodelling associated 5a
chr10_+_22510280 0.32 ENSDART00000109070
ENSDART00000182002
ENSDART00000192852
gigyf1b
GRB10 interacting GYF protein 1b
chr8_+_17168114 0.32 ENSDART00000183901
cenph
centromere protein H
chr1_+_52462068 0.32 ENSDART00000124682
glb1
galactosidase, beta 1
chr6_-_18976168 0.32 ENSDART00000170039
sept9b
septin 9b
chr4_+_331351 0.32 ENSDART00000132625
tulp4a
tubby like protein 4a
chr23_-_31913069 0.32 ENSDART00000135526
mtfr2
mitochondrial fission regulator 2
chr24_-_16905018 0.32 ENSDART00000066759
mtrr
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr14_+_94946 0.32 ENSDART00000165766
ENSDART00000163778
mcm7
minichromosome maintenance complex component 7
chr6_-_2154137 0.31 ENSDART00000162656
tgm5l
transglutaminase 5, like
chr19_+_19786117 0.31 ENSDART00000167757
ENSDART00000163546
hoxa1a
homeobox A1a
chr13_+_24584401 0.31 ENSDART00000057599
fuom
fucose mutarotase
chr16_+_14216581 0.31 ENSDART00000113093
gba
glucosidase, beta, acid
chr3_-_34296361 0.31 ENSDART00000181485
ENSDART00000113726
tnrc6c1
trinucleotide repeat containing 6C1
chr13_-_33114933 0.31 ENSDART00000140543
ENSDART00000075953
zfyve26
zinc finger, FYVE domain containing 26
chr20_-_3911546 0.31 ENSDART00000169787
cnksr3
cnksr family member 3
chr21_+_7298687 0.31 ENSDART00000187746
CU929160.1

chr23_+_26079467 0.31 ENSDART00000129617
atp6ap1b
ATPase H+ transporting accessory protein 1b
chr22_+_15343953 0.30 ENSDART00000045682
rrp36
ribosomal RNA processing 36
chr19_+_34169055 0.30 ENSDART00000135592
ENSDART00000186043
poc1bl
POC1 centriolar protein homolog B (Chlamydomonas), like
chr8_-_16725959 0.30 ENSDART00000183593
depdc1a
DEP domain containing 1a
chr7_+_9189547 0.30 ENSDART00000169783
pcsk6
proprotein convertase subtilisin/kexin type 6
chr25_-_19608382 0.30 ENSDART00000022279
ENSDART00000135201
ENSDART00000147223
ENSDART00000190220
ENSDART00000184242
ENSDART00000166824
gtse1
G-2 and S-phase expressed 1
chr16_-_28268201 0.30 ENSDART00000121671
ENSDART00000141911
si:dkey-12j5.1
si:dkey-12j5.1
chr18_+_8231138 0.30 ENSDART00000140193
arsa
arylsulfatase A
chr5_-_2636078 0.30 ENSDART00000122274
cita
citron rho-interacting serine/threonine kinase a
chr23_-_19051869 0.30 ENSDART00000140866
arfgef2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr5_-_22130937 0.30 ENSDART00000138606
las1l
LAS1-like, ribosome biogenesis factor
chr4_-_49801268 0.30 ENSDART00000185457
si:ch211-197e7.1
si:ch211-197e7.1
chr13_-_214122 0.30 ENSDART00000169273
ppp1r21
protein phosphatase 1, regulatory subunit 21
chr13_+_28732101 0.30 ENSDART00000015773
ldb1a
LIM domain binding 1a
chr5_-_54714789 0.30 ENSDART00000063357
ccnb1
cyclin B1
chr25_+_22107643 0.30 ENSDART00000089680
sigirr
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr22_+_29991834 0.29 ENSDART00000147728
si:dkey-286j15.3
si:dkey-286j15.3
chr8_+_17529151 0.29 ENSDART00000147760
si:ch73-70k4.1
si:ch73-70k4.1
chr9_+_24920677 0.29 ENSDART00000037025
slc39a10
solute carrier family 39 (zinc transporter), member 10
chr12_+_34827808 0.29 ENSDART00000105533
tepsin
TEPSIN, adaptor related protein complex 4 accessory protein
chr3_+_30500968 0.29 ENSDART00000103447
si:dkey-13n23.3
si:dkey-13n23.3
chr4_-_40972176 0.29 ENSDART00000152052
si:dkeyp-82h4.1
si:dkeyp-82h4.1
chr22_-_10165446 0.29 ENSDART00000142012
rbck1
RanBP-type and C3HC4-type zinc finger containing 1
chr25_-_25646806 0.29 ENSDART00000089066
tbc1d2b
TBC1 domain family, member 2B
chr15_-_4580763 0.29 ENSDART00000008170
rffl
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr20_+_46213553 0.28 ENSDART00000100532
stx7l
syntaxin 7-like
chr2_+_15128418 0.28 ENSDART00000141921
arhgap29b
Rho GTPase activating protein 29b
chr1_+_54737353 0.28 ENSDART00000130675
ENSDART00000162075
pi4k2a
phosphatidylinositol 4-kinase type 2 alpha
chr23_+_10146542 0.28 ENSDART00000048073
zgc:171775
zgc:171775
chr7_-_19923249 0.28 ENSDART00000078694
zgc:110591
zgc:110591
chr15_-_16177603 0.28 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr5_+_27404946 0.28 ENSDART00000121886
ENSDART00000005025
hdr
hematopoietic death receptor
chr16_+_19029297 0.28 ENSDART00000115263
ENSDART00000114954
rapgef5b
Rap guanine nucleotide exchange factor (GEF) 5b
chr25_-_14424406 0.28 ENSDART00000073609
prmt7
protein arginine methyltransferase 7
chr5_-_25072607 0.28 ENSDART00000145061
pnpla7b
patatin-like phospholipase domain containing 7b
chr5_-_25066780 0.28 ENSDART00000002118
ENSDART00000182575
pnpla7b
patatin-like phospholipase domain containing 7b
chr12_+_26538861 0.27 ENSDART00000152955
si:dkey-57h18.1
si:dkey-57h18.1

Network of associatons between targets according to the STRING database.

First level regulatory network of tfe3a+tfe3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.3 1.1 GO:0070199 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.2 0.6 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.2 0.5 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.2 0.5 GO:0065001 specification of axis polarity(GO:0065001)
0.2 0.5 GO:1990359 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.2 0.5 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.2 0.5 GO:2000008 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.1 0.4 GO:1901993 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.1 0.5 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
0.1 0.6 GO:0042766 nucleosome mobilization(GO:0042766)
0.1 0.6 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1 1.3 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 0.9 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.4 GO:0010664 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.1 0.7 GO:0055016 hypochord development(GO:0055016)
0.1 0.4 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.1 0.6 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.8 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.4 GO:0009098 leucine biosynthetic process(GO:0009098)
0.1 0.3 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.1 0.4 GO:0034969 histone arginine methylation(GO:0034969)
0.1 0.7 GO:0021570 rhombomere 4 development(GO:0021570) rhombomere 4 morphogenesis(GO:0021661)
0.1 0.3 GO:0071514 genetic imprinting(GO:0071514)
0.1 0.1 GO:0043393 regulation of protein binding(GO:0043393)
0.1 0.5 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.5 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.1 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.5 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.2 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.1 0.3 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.3 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.1 0.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.4 GO:0006013 mannose metabolic process(GO:0006013)
0.1 1.0 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.5 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.4 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.1 0.3 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 0.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.6 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 0.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.1 GO:0021588 cerebellum formation(GO:0021588)
0.1 0.3 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.5 GO:0033260 nuclear DNA replication(GO:0033260)
0.1 0.4 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.2 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 0.4 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.2 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.6 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.5 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.4 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.3 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.2 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.2 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.0 0.6 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.2 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.2 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.4 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0039703 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.0 0.7 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.4 GO:0060236 regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224)
0.0 0.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.0 0.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.3 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 1.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.6 GO:0035476 angioblast cell migration(GO:0035476)
0.0 0.1 GO:0046462 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 1.4 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.1 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.1 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.3 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.8 GO:0050821 protein stabilization(GO:0050821)
0.0 0.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:1903334 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.0 0.3 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 1.3 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 0.2 GO:0051694 skeletal muscle thin filament assembly(GO:0030240) pointed-end actin filament capping(GO:0051694)
0.0 0.4 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.2 GO:0021550 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.0 0.1 GO:0032615 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.0 0.2 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.1 GO:0017145 stem cell division(GO:0017145)
0.0 0.1 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.4 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.0 0.5 GO:0060021 palate development(GO:0060021)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.2 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.5 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.5 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.3 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852) water-soluble vitamin biosynthetic process(GO:0042364)
0.0 0.2 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.2 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 0.3 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.0 0.2 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.5 GO:0043049 otic placode formation(GO:0043049)
0.0 1.2 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.2 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.1 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.1 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.3 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.1 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 1.7 GO:0090504 epiboly(GO:0090504)
0.0 0.1 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.4 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.1 GO:0030323 respiratory tube development(GO:0030323) lung development(GO:0030324)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0003139 secondary heart field specification(GO:0003139)
0.0 0.3 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.3 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.1 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.1 GO:2001044 regulation of integrin-mediated signaling pathway(GO:2001044)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.3 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.3 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.1 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.1 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.0 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.2 GO:0043491 protein kinase B signaling(GO:0043491)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.2 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.4 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.4 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.6 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.2 GO:0032418 lysosome localization(GO:0032418)
0.0 0.0 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.1 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.4 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.7 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.4 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.4 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.4 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 1.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.2 0.5 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 0.5 GO:1990745 EARP complex(GO:1990745)
0.1 1.6 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.4 GO:0005880 nuclear microtubule(GO:0005880)
0.1 0.6 GO:0016589 NURF complex(GO:0016589)
0.1 0.4 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 0.2 GO:0005775 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.1 0.2 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 0.6 GO:0035101 FACT complex(GO:0035101)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.3 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.2 GO:0031511 Mis6-Sim4 complex(GO:0031511)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.2 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.4 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.3 GO:0016011 dystroglycan complex(GO:0016011)
0.0 0.4 GO:0070187 telosome(GO:0070187)
0.0 0.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 7.6 GO:0005764 lysosome(GO:0005764)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0072380 TRC complex(GO:0072380)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.4 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.5 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.4 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.1 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
0.0 0.4 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.1 GO:0000776 kinetochore(GO:0000776)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.3 GO:0030686 90S preribosome(GO:0030686)
0.0 0.6 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0032797 SMN complex(GO:0032797)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.5 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 0.5 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.2 0.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 1.3 GO:0015232 heme transporter activity(GO:0015232)
0.2 0.6 GO:0030586 [methionine synthase] reductase activity(GO:0030586)
0.1 1.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.7 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.6 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 0.3 GO:0043621 protein self-association(GO:0043621)
0.1 0.4 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.3 GO:0042806 fucose binding(GO:0042806)
0.1 1.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.5 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.3 GO:0052834 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.3 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.2 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.2 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.6 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.6 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.2 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.1 0.1 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1 0.6 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.4 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.2 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.0 0.5 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 1.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.4 GO:0008296 deoxyribonuclease I activity(GO:0004530) 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0038132 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.2 GO:0043531 ADP binding(GO:0043531)
0.0 0.7 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.5 GO:2001069 glycogen binding(GO:2001069)
0.0 0.2 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.4 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 3.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.4 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.5 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.8 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.5 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 1.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0004067 asparaginase activity(GO:0004067)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0043236 laminin binding(GO:0043236)
0.0 0.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.5 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 1.4 GO:0042803 protein homodimerization activity(GO:0042803)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 0.8 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.7 PID AURORA A PATHWAY Aurora A signaling
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 2.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 0.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 2.0 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.4 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 2.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism