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PRJEB1986: zebrafish developmental stages transcriptome

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Results for thrb

Z-value: 0.30

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Transcription factors associated with thrb

Gene Symbol Gene ID Gene Info
thrb
ENSDARG00000021163 thyroid hormone receptor beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
thrbdr11_v1_chr19_-_17658160_17658253-0.077.9e-01Click!

Activity profile of thrb motif

Sorted Z-values of thrb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_9318891 0.78 ENSDART00000137364
si:dkey-33c12.3
si:dkey-33c12.3
chr15_-_34408777 0.65 ENSDART00000139934
agmo
alkylglycerol monooxygenase
chr13_-_22862133 0.63 ENSDART00000138563
pbld2
phenazine biosynthesis-like protein domain containing 2
chr5_+_38673168 0.57 ENSDART00000135267
si:dkey-58f10.12
si:dkey-58f10.12
chr15_-_23645810 0.33 ENSDART00000168845
ckmb
creatine kinase, muscle b
chr19_-_32804535 0.31 ENSDART00000175613
ENSDART00000052098
nt5c1aa
5'-nucleotidase, cytosolic IAa
chr20_-_35750810 0.29 ENSDART00000153072
adgrf8
adhesion G protein-coupled receptor F8
chr6_+_60112200 0.29 ENSDART00000008243
prelid3b
PRELI domain containing 3
chr15_+_5088210 0.12 ENSDART00000183423
mxf
myxovirus (influenza virus) resistance F
chr3_+_34846201 0.11 ENSDART00000055263
itga3a
integrin, alpha 3a
chr9_-_3034064 0.11 ENSDART00000115138
ENSDART00000144046
rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr24_-_1023112 0.11 ENSDART00000147508
ENSDART00000066863
ralaa
v-ral simian leukemia viral oncogene homolog Aa (ras related)
chr5_+_28857969 0.09 ENSDART00000149850
si:ch211-186e20.2
si:ch211-186e20.2
chr11_-_42980535 0.09 ENSDART00000181160
ENSDART00000192064
CABZ01069998.1

chr15_-_34878388 0.08 ENSDART00000154094
mgat1a
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a
chr13_+_33462232 0.08 ENSDART00000177841
zgc:136302
zgc:136302
chr2_-_5199431 0.07 ENSDART00000063384
phb2a
prohibitin 2a
chr23_+_36653376 0.06 ENSDART00000053189
gpr182
G protein-coupled receptor 182
chr22_-_6219092 0.02 ENSDART00000150040
si:ch211-274k16.2
si:ch211-274k16.2
chr7_-_8014186 0.01 ENSDART00000190012
si:cabz01030277.1
si:cabz01030277.1
chr4_+_37710744 0.01 ENSDART00000192791
si:dkey-3p4.8
si:dkey-3p4.8

Network of associatons between targets according to the STRING database.

First level regulatory network of thrb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.3 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.3 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling