Project

PRJEB1986: zebrafish developmental stages transcriptome

Navigation
Downloads

Results for tlx1

Z-value: 0.67

Motif logo

logo of

Transcription factors associated with tlx1

Gene Symbol Gene ID Gene Info
tlx1
ENSDARG00000003965 T cell leukemia homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tlx1dr11_v1_chr13_-_28272299_28272299-0.733.5e-04Click!

Activity profile of tlx1 motif

Sorted Z-values of tlx1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_44939104 3.14 ENSDART00000192903
vil1
villin 1
chr7_+_14291323 2.88 ENSDART00000053521
rhcga
Rh family, C glycoprotein a
chr1_+_49568335 2.73 ENSDART00000142957
col17a1a
collagen, type XVII, alpha 1a
chr2_+_37207461 2.67 ENSDART00000138952
ENSDART00000132856
ENSDART00000137272
ENSDART00000143468
apoda.2
apolipoprotein Da, duplicate 2
chr11_-_103136 2.15 ENSDART00000173308
ENSDART00000162982
elmo2
engulfment and cell motility 2
chr25_-_30394746 2.08 ENSDART00000185346
si:ch211-93f2.1
si:ch211-93f2.1
chr22_+_38229321 2.07 ENSDART00000132670
ENSDART00000104504
si:ch211-284e20.8
si:ch211-284e20.8
chr12_+_22607761 2.06 ENSDART00000153112
si:dkey-219e21.2
si:dkey-219e21.2
chr23_-_45504991 1.97 ENSDART00000148761
col24a1
collagen type XXIV alpha 1
chr25_-_4146947 1.80 ENSDART00000129268
fads2
fatty acid desaturase 2
chr4_+_74131530 1.70 ENSDART00000174125
CABZ01072523.1

chr6_+_53349966 1.60 ENSDART00000167079
si:ch211-161c3.5
si:ch211-161c3.5
chr3_+_57038033 1.50 ENSDART00000162930
bahcc1a
BAH domain and coiled-coil containing 1a
chr19_+_40379771 1.44 ENSDART00000017917
ENSDART00000110699
vps50
vps50
VPS50 EARP/GARPII complex subunit
VPS50 EARP/GARPII complex subunit
chr3_+_24482999 1.41 ENSDART00000059179
nptxra
neuronal pentraxin receptor a
chr11_+_38332419 1.40 ENSDART00000005864
CDK18
si:dkey-166c18.1
chr17_-_22067451 1.39 ENSDART00000156872
ttbk1b
tau tubulin kinase 1b
chr16_+_16849220 1.39 ENSDART00000047409
ENSDART00000142155
myh14
myosin, heavy chain 14, non-muscle
chr1_-_22757145 1.25 ENSDART00000134719
prom1b
prominin 1 b
chr8_+_53423408 1.24 ENSDART00000164792
cacna1db
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr5_-_67629263 1.21 ENSDART00000133753
zbtb20
zinc finger and BTB domain containing 20
chr13_-_9895564 1.21 ENSDART00000169831
ENSDART00000142629
si:ch211-117n7.6
si:ch211-117n7.6
chr6_-_35401282 1.21 ENSDART00000127612
rgs5a
regulator of G protein signaling 5a
chr12_+_33403694 1.20 ENSDART00000124083
fasn
fatty acid synthase
chr2_-_53925308 1.17 ENSDART00000190705
FO834855.1

chr8_-_53108207 1.15 ENSDART00000111023
b3galt4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
chr11_-_34147205 1.13 ENSDART00000173216
atp13a3
ATPase 13A3
chr20_+_16750177 1.06 ENSDART00000185357
calm1b
calmodulin 1b
chr3_-_5664123 1.02 ENSDART00000145866
si:ch211-106h11.1
si:ch211-106h11.1
chr16_+_14029283 1.01 ENSDART00000146165
ENSDART00000132075
rusc1
RUN and SH3 domain containing 1
chr7_-_51953807 0.99 ENSDART00000174102
ENSDART00000145645
ENSDART00000052054
cyp2x10.2
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr17_+_37645633 0.96 ENSDART00000085500
tmem229b
transmembrane protein 229B
chr9_-_22057658 0.93 ENSDART00000101944
crygmxl1
crystallin, gamma MX, like 1
chr11_-_270210 0.92 ENSDART00000005217
ENSDART00000172779
alas1
aminolevulinate, delta-, synthase 1
chr13_-_31829786 0.90 ENSDART00000138667
sertad4
SERTA domain containing 4
chr5_-_16218777 0.89 ENSDART00000141698
kremen1
kringle containing transmembrane protein 1
chr17_-_45040813 0.89 ENSDART00000075514
entpd5a
ectonucleoside triphosphate diphosphohydrolase 5a
chr1_-_22756898 0.89 ENSDART00000158915
prom1b
prominin 1 b
chr23_-_38497705 0.87 ENSDART00000109493
tshz2
teashirt zinc finger homeobox 2
chr18_-_43880020 0.83 ENSDART00000185638
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr1_-_58059134 0.83 ENSDART00000160970
caspb
caspase b
chr23_-_20100436 0.81 ENSDART00000143445
si:dkey-32e6.6
si:dkey-32e6.6
chr9_-_22831836 0.81 ENSDART00000142585
neb
nebulin
chr2_+_55982940 0.80 ENSDART00000097753
ENSDART00000097751
nmrk2
nicotinamide riboside kinase 2
chr5_+_22791686 0.74 ENSDART00000014806
npas2
neuronal PAS domain protein 2
chr7_-_52096498 0.70 ENSDART00000098688
ENSDART00000098690
cyp2x10.2
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr8_+_1284784 0.70 ENSDART00000061663
fbxl17
F-box and leucine-rich repeat protein 17
chr7_-_51953613 0.67 ENSDART00000142042
cyp2x10.2
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr10_+_573667 0.66 ENSDART00000110384
smad4a
SMAD family member 4a
chr22_-_16400484 0.65 ENSDART00000135987
lama3
laminin, alpha 3
chr16_-_22585289 0.65 ENSDART00000134239
ENSDART00000193959
ENSDART00000077998
si:dkey-238m4.3
cgna
si:dkey-238m4.3
cingulin a
chr7_-_22132265 0.64 ENSDART00000125284
ENSDART00000112978
nlgn2a
neuroligin 2a
chr17_-_22048233 0.63 ENSDART00000155203
ttbk1b
tau tubulin kinase 1b
chr10_-_7857494 0.62 ENSDART00000143215
inpp5ja
inositol polyphosphate-5-phosphatase Ja
chr21_+_39336285 0.62 ENSDART00000139677
si:ch211-274p24.4
si:ch211-274p24.4
chr23_-_6765653 0.60 ENSDART00000192310
FP102169.1

chr7_+_52135791 0.59 ENSDART00000098705
cyp2x12
cytochrome P450, family 2, subfamily X, polypeptide 12
chr2_+_50722439 0.59 ENSDART00000188927
fyco1b
FYVE and coiled-coil domain containing 1b
chr24_+_25692802 0.59 ENSDART00000190493
camk2n2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr3_-_33574576 0.56 ENSDART00000184881
CR847537.1

chr7_-_35126374 0.54 ENSDART00000141211
hsd11b2
hydroxysteroid (11-beta) dehydrogenase 2
chr14_-_32503363 0.54 ENSDART00000034883
mcf2a
MCF.2 cell line derived transforming sequence a
chr25_-_31118923 0.54 ENSDART00000009126
ENSDART00000188286
kras
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
chr1_+_35194454 0.53 ENSDART00000165389
sc:d189
sc:d189
chr12_-_2518178 0.52 ENSDART00000128677
ENSDART00000086510
mapk8b
mitogen-activated protein kinase 8b
chr5_+_28398449 0.52 ENSDART00000165292
nsmfb
NMDA receptor synaptonuclear signaling and neuronal migration factor b
chr22_+_39058269 0.51 ENSDART00000113362
ip6k1
inositol hexakisphosphate kinase 1
chr12_+_35654749 0.50 ENSDART00000169889
ENSDART00000167873
baiap2b
BAI1-associated protein 2b
chr5_-_30074332 0.48 ENSDART00000147963
bco2a
beta-carotene oxygenase 2a
chr8_+_9699111 0.48 ENSDART00000111853
gripap1
GRIP1 associated protein 1
chr20_-_2134620 0.47 ENSDART00000064375
tmem244
transmembrane protein 244
chr5_-_57655092 0.47 ENSDART00000074290
mia
melanoma inhibitory activity
chr6_+_39184236 0.47 ENSDART00000156187
tac3b
tachykinin 3b
chr18_-_2433011 0.44 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr17_+_52822422 0.43 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr8_+_44623540 0.43 ENSDART00000141513
grk5l
G protein-coupled receptor kinase 5 like
chr17_-_29771639 0.42 ENSDART00000086201
ush2a
Usher syndrome 2A (autosomal recessive, mild)
chr12_+_13405445 0.37 ENSDART00000089042
kcnh4b
potassium voltage-gated channel, subfamily H (eag-related), member 4b
chr13_-_41482064 0.36 ENSDART00000188322
ENSDART00000164732
pcdh15a
protocadherin-related 15a
chr5_+_31283576 0.35 ENSDART00000133743
camkk1a
calcium/calmodulin-dependent protein kinase kinase 1, alpha a
chr7_+_47316944 0.35 ENSDART00000173534
dpy19l3
dpy-19 like C-mannosyltransferase 3
chr11_+_14937904 0.35 ENSDART00000185103
CR550302.3

chr19_+_21818460 0.34 ENSDART00000189427
ENSDART00000180525
CU856623.1

chr1_-_28629471 0.33 ENSDART00000121758
ednrba
endothelin receptor Ba
chr6_+_41957280 0.33 ENSDART00000050114
oxtr
oxytocin receptor
chr17_-_50233493 0.32 ENSDART00000172266
fosaa
v-fos FBJ murine osteosarcoma viral oncogene homolog Aa
chr17_-_31308658 0.31 ENSDART00000124505
bahd1
bromo adjacent homology domain containing 1
chr8_+_44722140 0.31 ENSDART00000163381
elmod3
ELMO/CED-12 domain containing 3
chr13_+_4888351 0.31 ENSDART00000145940
micu1
mitochondrial calcium uptake 1
chr10_+_7636811 0.30 ENSDART00000160673
hint1
histidine triad nucleotide binding protein 1
chr22_-_22416337 0.29 ENSDART00000142947
ENSDART00000089569
camsap2a
calmodulin regulated spectrin-associated protein family, member 2a
chr20_+_54383838 0.28 ENSDART00000157737
lrfn5b
leucine rich repeat and fibronectin type III domain containing 5b
chr4_-_51460013 0.27 ENSDART00000193382
CR628395.1

chr17_+_30546579 0.27 ENSDART00000154385
nhsl1a
NHS-like 1a
chr20_+_23960525 0.26 ENSDART00000042123
cx52.6
connexin 52.6
chr21_-_2707768 0.26 ENSDART00000165384
CABZ01101739.1

chr11_+_14284866 0.26 ENSDART00000163729
si:ch211-262i1.3
si:ch211-262i1.3
chr19_+_22727940 0.25 ENSDART00000052509
trhrb
thyrotropin-releasing hormone receptor b
chr13_+_18371208 0.25 ENSDART00000138172
ccar1
cell division cycle and apoptosis regulator 1
chr2_-_37352514 0.23 ENSDART00000140498
ENSDART00000186422
skila
SKI-like proto-oncogene a
chr17_+_19630068 0.23 ENSDART00000182619
rgs7a
regulator of G protein signaling 7a
chr18_-_39473055 0.22 ENSDART00000122930
scg3
secretogranin III
chr18_+_41560822 0.22 ENSDART00000158503
baz1b
bromodomain adjacent to zinc finger domain, 1B
chr23_-_14057191 0.21 ENSDART00000154908
adcy6a
adenylate cyclase 6a
chr15_+_22722684 0.21 ENSDART00000156760
grik4
glutamate receptor, ionotropic, kainate 4
chr20_+_2134816 0.21 ENSDART00000039249
l3mbtl3
l(3)mbt-like 3 (Drosophila)
chr8_+_41647539 0.19 ENSDART00000136492
ENSDART00000138799
ENSDART00000134404
si:ch211-158d24.4
si:ch211-158d24.4
chr7_+_23292133 0.18 ENSDART00000134489
htr2cl1
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1
chr7_+_57109214 0.17 ENSDART00000135068
ENSDART00000098412
enosf1
enolase superfamily member 1
chr13_-_32577386 0.16 ENSDART00000016535
kcns3a
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3a
chr8_-_34052019 0.16 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pbx3b
pre-B-cell leukemia homeobox 3b
chr3_-_34599662 0.15 ENSDART00000055259
nmrk1
nicotinamide riboside kinase 1
chr3_-_37681824 0.15 ENSDART00000185858
gpatch8
G patch domain containing 8
chr15_-_14469704 0.14 ENSDART00000185077
numbl
numb homolog (Drosophila)-like
chr2_-_2937225 0.14 ENSDART00000168132
si:ch1073-82l19.1
si:ch1073-82l19.1
chr11_-_13341051 0.14 ENSDART00000121872
mast3b
microtubule associated serine/threonine kinase 3b
chr5_+_35502290 0.13 ENSDART00000191222
CR762390.1

chr23_+_21278948 0.13 ENSDART00000156701
ENSDART00000033970
ubr4
ubiquitin protein ligase E3 component n-recognin 4
chr13_+_15682803 0.13 ENSDART00000188063
CR931980.1

chr7_-_73845736 0.12 ENSDART00000193414
zgc:173552
zgc:173552
chr17_+_52823015 0.12 ENSDART00000160507
ENSDART00000186979
meis2a
Meis homeobox 2a
chr20_-_53949798 0.11 ENSDART00000153435
ppp2r5cb
protein phosphatase 2, regulatory subunit B', gamma b
chr21_+_21817975 0.11 ENSDART00000151292
ENSDART00000166704
neu3.5
sialidase 3 (membrane sialidase), tandem duplicate 5
chr12_-_36521947 0.10 ENSDART00000152946
unc13d
unc-13 homolog D (C. elegans)
chr1_+_4101741 0.10 ENSDART00000163793
slitrk6
SLIT and NTRK-like family, member 6
chr1_-_56363108 0.09 ENSDART00000021878
gcgrb
glucagon receptor b
chr20_+_25581627 0.08 ENSDART00000030229
cyp2p9
cytochrome P450, family 2, subfamily P, polypeptide 9
chr22_+_11857356 0.08 ENSDART00000179540
mras
muscle RAS oncogene homolog
chr6_+_2951645 0.05 ENSDART00000183181
ENSDART00000181271
ptprfa
protein tyrosine phosphatase, receptor type, f, a
chr13_+_37040789 0.04 ENSDART00000063412
esr2b
estrogen receptor 2b
chr4_-_17680493 0.04 ENSDART00000180131
BX890572.2

chr7_+_57108823 0.03 ENSDART00000184943
ENSDART00000055956
enosf1
enolase superfamily member 1
chr7_+_52122224 0.02 ENSDART00000174268
cyp2x12
cytochrome P450, family 2, subfamily X, polypeptide 12
chr21_+_5257018 0.01 ENSDART00000183100
ENSDART00000191525
loxhd1a
lipoxygenase homology domains 1a
chr2_+_30969029 0.01 ENSDART00000085242
lpin2
lipin 2
chr15_-_38202630 0.00 ENSDART00000183772
rhoga
ras homolog family member Ga

Network of associatons between targets according to the STRING database.

First level regulatory network of tlx1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.4 2.9 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.3 2.0 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.2 1.2 GO:0006660 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.2 0.9 GO:0048903 anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.1 0.8 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 0.5 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 0.6 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.5 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.3 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.3 GO:0007567 parturition(GO:0007567) neurohypophysis development(GO:0021985) maternal process involved in parturition(GO:0060137)
0.1 0.8 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.9 GO:0072506 phosphate ion homeostasis(GO:0055062) trivalent inorganic anion homeostasis(GO:0072506)
0.1 2.7 GO:0007568 aging(GO:0007568)
0.1 0.6 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 0.5 GO:0034650 cortisol metabolic process(GO:0034650)
0.1 2.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.6 GO:0097105 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.9 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.5 GO:0016119 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.3 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 2.2 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 1.4 GO:0009648 photoperiodism(GO:0009648)
0.0 1.8 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.4 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.5 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.8 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 1.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 2.0 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.0 0.4 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 1.9 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.4 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 2.2 GO:0006909 phagocytosis(GO:0006909)
0.0 0.5 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.2 GO:0042493 response to drug(GO:0042493)
0.0 0.4 GO:0048264 determination of ventral identity(GO:0048264)
0.0 1.9 GO:0008544 epidermis development(GO:0008544)
0.0 0.3 GO:0050935 iridophore differentiation(GO:0050935)
0.0 1.2 GO:0070509 calcium ion import(GO:0070509)
0.0 0.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0005592 collagen type XI trimer(GO:0005592)
0.6 3.1 GO:0032433 filopodium tip(GO:0032433)
0.5 1.4 GO:1990745 EARP complex(GO:1990745)
0.2 2.0 GO:0071914 prominosome(GO:0071914)
0.2 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.2 0.8 GO:0061702 inflammasome complex(GO:0061702)
0.1 0.7 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 0.5 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.5 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:1990246 uniplex complex(GO:1990246)
0.0 1.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 2.0 GO:0016459 myosin complex(GO:0016459)
0.0 1.1 GO:0005604 basement membrane(GO:0005604)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 0.8 GO:0070052 collagen V binding(GO:0070052)
0.1 0.9 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 2.9 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.3 GO:0004990 oxytocin receptor activity(GO:0004990)
0.1 0.6 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 1.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.6 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 0.8 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 3.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.5 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 0.9 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.5 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 2.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.3 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.3 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.0 1.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 2.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 2.1 GO:0017124 SH3 domain binding(GO:0017124)
0.0 2.2 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 4.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.7 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.5 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.2 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.4 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 1.1 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.5 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.0 1.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.1 1.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.5 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 0.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 2.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization