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PRJEB1986: zebrafish developmental stages transcriptome

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Results for xbp1

Z-value: 2.21

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Transcription factors associated with xbp1

Gene Symbol Gene ID Gene Info
xbp1
ENSDARG00000035622 X-box binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
xbp1dr11_v1_chr5_-_15948833_159489200.771.2e-04Click!

Activity profile of xbp1 motif

Sorted Z-values of xbp1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_990149 8.26 ENSDART00000054367
kdelr2b
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2b
chr16_+_20904754 6.96 ENSDART00000006043
hoxa11b
homeobox A11b
chr3_+_33300522 6.13 ENSDART00000114023
hspb9
heat shock protein, alpha-crystallin-related, 9
chr10_+_16165533 5.82 ENSDART00000065045
prrc1
proline-rich coiled-coil 1
chr3_-_25377163 5.38 ENSDART00000055490
kpna2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr6_+_13506841 4.99 ENSDART00000032331
gmppab
GDP-mannose pyrophosphorylase Ab
chr25_+_3759553 4.87 ENSDART00000180601
ENSDART00000055845
ENSDART00000157050
ENSDART00000153905
thoc5
THO complex 5
chr15_-_29388012 4.71 ENSDART00000115032
serpinh1b
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr24_+_14214831 4.71 ENSDART00000004664
tram1
translocation associated membrane protein 1
chr2_-_9527129 4.65 ENSDART00000157422
ENSDART00000004398
cope
coatomer protein complex, subunit epsilon
chr21_+_10701834 4.54 ENSDART00000192473
lman1
lectin, mannose-binding, 1
chr21_+_10702031 4.24 ENSDART00000102304
lman1
lectin, mannose-binding, 1
chr4_-_77979432 4.08 ENSDART00000049170
zgc:85975
zgc:85975
chr23_-_18572521 4.04 ENSDART00000138599
ssr4
signal sequence receptor, delta
chr6_+_3864040 4.01 ENSDART00000013743
gorasp2
golgi reassembly stacking protein 2
chr3_+_53773256 4.01 ENSDART00000170461
col5a3a
collagen, type V, alpha 3a
chr6_-_42388608 3.95 ENSDART00000049425
sec61a1l
Sec61 translocon alpha 1 subunit, like
chr7_+_32693890 3.67 ENSDART00000121972
slc39a13
solute carrier family 39 (zinc transporter), member 13
chr12_-_16452200 3.64 ENSDART00000037601
rpp30
ribonuclease P/MRP 30 subunit
chr1_+_38142354 3.55 ENSDART00000179352
galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr2_-_22363460 3.49 ENSDART00000158486
selenof
selenoprotein F
chr9_-_27748868 3.42 ENSDART00000190306
tbccd1
TBCC domain containing 1
chr5_+_2002804 3.38 ENSDART00000064088
vkorc1l1
vitamin K epoxide reductase complex, subunit 1-like 1
chr7_+_44715224 3.38 ENSDART00000184630
si:dkey-56m19.5
si:dkey-56m19.5
chr16_-_5115993 3.25 ENSDART00000138654
ttk
ttk protein kinase
chr25_-_3759322 3.17 ENSDART00000088077
zgc:158398
zgc:158398
chr23_-_18572685 3.14 ENSDART00000047175
ssr4
signal sequence receptor, delta
chr1_-_53277187 3.10 ENSDART00000131520
znf330
zinc finger protein 330
chr1_-_44484 3.10 ENSDART00000171547
ENSDART00000164075
ENSDART00000168091
tmem39a
transmembrane protein 39A
chr1_-_53277660 3.07 ENSDART00000014232
znf330
zinc finger protein 330
chr5_+_69278089 3.06 ENSDART00000136656
selenom
selenoprotein M
chr14_-_16082806 3.05 ENSDART00000165656
mxd3
MAX dimerization protein 3
chr2_-_1227221 3.04 ENSDART00000130897
ABCF3
ATP binding cassette subfamily F member 3
chr22_+_31059919 3.02 ENSDART00000077063
sec13
SEC13 homolog, nuclear pore and COPII coat complex component
chr19_+_18903533 3.00 ENSDART00000157523
ENSDART00000166562
slc39a7
solute carrier family 39 (zinc transporter), member 7
chr9_+_34950942 2.99 ENSDART00000077800
tfdp1a
transcription factor Dp-1, a
chr16_+_38159758 2.99 ENSDART00000058666
ENSDART00000112165
pi4kb
phosphatidylinositol 4-kinase, catalytic, beta
chr4_-_13613148 2.98 ENSDART00000067164
ENSDART00000111247
irf5
interferon regulatory factor 5
chr19_-_46219035 2.93 ENSDART00000170601
si:ch1073-228h2.2
si:ch1073-228h2.2
chr3_+_28860283 2.88 ENSDART00000077235
alg1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr11_+_30647545 2.88 ENSDART00000114792
gb:eh507706
expressed sequence EH507706
chr5_-_56943064 2.82 ENSDART00000146991
si:ch211-127d4.3
si:ch211-127d4.3
chr19_+_26640096 2.81 ENSDART00000067793
ints3
integrator complex subunit 3
chr21_+_17016337 2.79 ENSDART00000065755
gpn3
GPN-loop GTPase 3
chr20_-_21672970 2.73 ENSDART00000133286
si:ch211-207i1.2
si:ch211-207i1.2
chr1_+_17593392 2.72 ENSDART00000078889
helt
helt bHLH transcription factor
chr6_-_32087108 2.72 ENSDART00000150934
ENSDART00000130627
alg6
asparagine-linked glycosylation 6 (alpha-1,3,-glucosyltransferase)
chr17_+_23311377 2.69 ENSDART00000128073
ppp1r3ca
protein phosphatase 1, regulatory subunit 3Ca
chr25_+_35062353 2.68 ENSDART00000089844
zgc:113983
zgc:113983
chr1_-_156375 2.68 ENSDART00000160221
pcid2
PCI domain containing 2
chr15_-_18115540 2.65 ENSDART00000131639
ENSDART00000047902
arcn1b
archain 1b
chr5_+_24543862 2.65 ENSDART00000029699
atp6v0a2b
ATPase H+ transporting V0 subunit a2b
chr17_-_24866727 2.61 ENSDART00000027957
hmgcl
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr1_-_53277413 2.59 ENSDART00000150579
znf330
zinc finger protein 330
chr4_+_13568469 2.58 ENSDART00000171235
ENSDART00000136152
calua
calumenin a
chr21_+_43882274 2.54 ENSDART00000075672
sra1
steroid receptor RNA activator 1
chr1_+_27825980 2.53 ENSDART00000160524
pspc1
paraspeckle component 1
chr18_-_16924221 2.51 ENSDART00000122102
wee1
WEE1 G2 checkpoint kinase
chr14_-_26411918 2.48 ENSDART00000020582
tmed9
transmembrane p24 trafficking protein 9
chr3_-_55092051 2.46 ENSDART00000053077
hbba2
hemoglobin, beta adult 2
chr10_-_8434816 2.39 ENSDART00000108643
tctn1
tectonic family member 1
chr18_-_18587745 2.34 ENSDART00000191973
sf3b3
splicing factor 3b, subunit 3
chr18_-_34170918 2.32 ENSDART00000015079
slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr13_+_36595618 2.30 ENSDART00000022684
cnih1
cornichon family AMPA receptor auxiliary protein 1
chr3_-_18384501 2.26 ENSDART00000027630
kdelr2a
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2a
chr10_-_22150419 2.25 ENSDART00000006173
cldn7b
claudin 7b
chr25_-_37262220 2.24 ENSDART00000153789
ENSDART00000155182
rfwd3
ring finger and WD repeat domain 3
chr9_-_2594410 2.23 ENSDART00000188306
ENSDART00000164276
sp9
sp9 transcription factor
chr9_+_30112423 2.22 ENSDART00000112398
ENSDART00000013591
tfg
trk-fused gene
chr19_+_7549854 2.22 ENSDART00000138866
ENSDART00000151758
pbxip1a
pre-B-cell leukemia homeobox interacting protein 1a
chr10_+_35265083 2.20 ENSDART00000048831
tmem120a
transmembrane protein 120A
chr1_+_29798140 2.20 ENSDART00000019743
tm9sf2
transmembrane 9 superfamily member 2
chr11_+_7276983 2.15 ENSDART00000172407
ENSDART00000161176
ENSDART00000161041
ENSDART00000165536
si:ch73-238c9.1
si:ch73-238c9.1
chr20_-_1120056 2.13 ENSDART00000040680
rngtt
RNA guanylyltransferase and 5'-phosphatase
chr25_-_3034668 2.10 ENSDART00000053405
scamp2
secretory carrier membrane protein 2
chr2_+_37176814 2.10 ENSDART00000048277
ENSDART00000176827
copa
coatomer protein complex, subunit alpha
chr5_-_29750377 2.10 ENSDART00000051474
barhl1a
BarH-like homeobox 1a
chr5_+_65086856 2.09 ENSDART00000169209
ENSDART00000162409
ptrh1
peptidyl-tRNA hydrolase 1 homolog
chr14_+_9581896 2.08 ENSDART00000114563
tmem129
transmembrane protein 129, E3 ubiquitin protein ligase
chr6_+_6779114 2.03 ENSDART00000163493
ENSDART00000143359
sec23b
Sec23 homolog B, COPII coat complex component
chr6_-_35052145 2.02 ENSDART00000073970
ENSDART00000185790
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr12_+_19362335 1.99 ENSDART00000041711
gspt1
G1 to S phase transition 1
chr20_+_29565906 1.98 ENSDART00000062383
ywhaqa
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a
chr15_-_29387446 1.96 ENSDART00000145976
ENSDART00000035096
serpinh1b
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr21_+_10756154 1.93 ENSDART00000074833
rx3
retinal homeobox gene 3
chr19_-_30404096 1.91 ENSDART00000103475
agr2
anterior gradient 2
chr9_+_23825440 1.91 ENSDART00000138470
ints6
integrator complex subunit 6
chr7_+_20019125 1.87 ENSDART00000186391
bcl6b
B-cell CLL/lymphoma 6, member B
chr19_-_7540821 1.87 ENSDART00000143958
lix1l
limb and CNS expressed 1 like
chr1_+_38142715 1.87 ENSDART00000079928
galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr22_+_24215007 1.83 ENSDART00000162227
glrx2
glutaredoxin 2
chr3_-_180860 1.83 ENSDART00000059956
ENSDART00000192506
kdelr3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr22_-_817479 1.83 ENSDART00000123487
zgc:153675
zgc:153675
chr22_-_10152629 1.82 ENSDART00000144209
rbck1
RanBP-type and C3HC4-type zinc finger containing 1
chr8_-_37461835 1.81 ENSDART00000013446
eif2d
eukaryotic translation initiation factor 2D
chr8_-_34767412 1.79 ENSDART00000164901
CABZ01049825.1

chr21_-_2958422 1.79 ENSDART00000174091
zgc:194215
zgc:194215
chr17_+_24446353 1.74 ENSDART00000140467
ugp2b
UDP-glucose pyrophosphorylase 2b
chr6_+_26948093 1.73 ENSDART00000153595
farp2
FERM, RhoGEF and pleckstrin domain protein 2
chr17_+_24446705 1.73 ENSDART00000163221
ugp2b
UDP-glucose pyrophosphorylase 2b
chr12_-_35582521 1.71 ENSDART00000162175
ENSDART00000168958
sec24c
SEC24 homolog C, COPII coat complex component
chr12_+_31783066 1.70 ENSDART00000105584
lrrc59
leucine rich repeat containing 59
chr1_-_26063188 1.70 ENSDART00000168640
pdcd4a
programmed cell death 4a
chr24_-_26485098 1.68 ENSDART00000135496
ENSDART00000009609
ENSDART00000133782
ENSDART00000141029
ENSDART00000113739
eif5a
eukaryotic translation initiation factor 5A
chr15_-_29326254 1.67 ENSDART00000114492
si:dkey-52l18.4
si:dkey-52l18.4
chr8_+_11471350 1.66 ENSDART00000092355
ENSDART00000136184
tjp2b
tight junction protein 2b (zona occludens 2)
chr16_-_26676685 1.66 ENSDART00000103431
esrp1
epithelial splicing regulatory protein 1
chr10_+_39212898 1.63 ENSDART00000159501
stt3a
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr18_-_34171280 1.62 ENSDART00000122321
slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr5_-_30516646 1.59 ENSDART00000014666
arcn1a
archain 1a
chr16_+_23984755 1.55 ENSDART00000145328
apoc2
apolipoprotein C-II
chr10_-_3427589 1.53 ENSDART00000133452
ENSDART00000037183
tmed2
transmembrane p24 trafficking protein 2
chr12_+_46683114 1.50 ENSDART00000079656
tvp23b
trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
chr12_-_3773869 1.50 ENSDART00000092983
si:ch211-166g5.4
si:ch211-166g5.4
chr2_+_36608387 1.49 ENSDART00000159541
pak2a
p21 protein (Cdc42/Rac)-activated kinase 2a
chr9_+_25840720 1.49 ENSDART00000024572
gtdc1
glycosyltransferase-like domain containing 1
chr3_+_27770110 1.46 ENSDART00000017962
eci1
enoyl-CoA delta isomerase 1
chr12_+_1592146 1.45 ENSDART00000184575
ENSDART00000192902
SLC39A11
solute carrier family 39 member 11
chr19_-_30403922 1.44 ENSDART00000181841
agr2
anterior gradient 2
chr20_-_438646 1.44 ENSDART00000009196
ufl1
UFM1-specific ligase 1
chr2_-_30912307 1.43 ENSDART00000188653
myl12.2
myosin, light chain 12, genome duplicate 2
chr16_+_23984179 1.43 ENSDART00000175879
apoc2
apolipoprotein C-II
chr16_-_41717063 1.42 ENSDART00000084610
cep85
centrosomal protein 85
chr1_+_46598764 1.42 ENSDART00000053240
cab39l
calcium binding protein 39-like
chr10_-_44305180 1.41 ENSDART00000187552
CDK2AP1
cyclin dependent kinase 2 associated protein 1
chr11_+_7276824 1.41 ENSDART00000185992
si:ch73-238c9.1
si:ch73-238c9.1
chr12_+_19362547 1.41 ENSDART00000180148
gspt1
G1 to S phase transition 1
chr25_+_21829777 1.39 ENSDART00000027393
ckmt1
creatine kinase, mitochondrial 1
chr2_-_7757273 1.39 ENSDART00000136074
b3gnt5b
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5b
chr12_+_16452912 1.39 ENSDART00000192467
kif20bb
kinesin family member 20Bb
chr1_-_9486214 1.39 ENSDART00000137821
micall2b
mical-like 2b
chr9_-_27857265 1.38 ENSDART00000177513
ENSDART00000143166
ENSDART00000115313
si:rp71-45g20.4
si:rp71-45g20.4
chr10_+_39212601 1.35 ENSDART00000168778
stt3a
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr1_-_7673376 1.33 ENSDART00000013264
arglu1b
arginine and glutamate rich 1b
chr12_+_16452575 1.33 ENSDART00000058665
kif20bb
kinesin family member 20Bb
chr17_-_24866964 1.31 ENSDART00000190601
ENSDART00000192547
hmgcl
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr25_+_32157326 1.29 ENSDART00000112588
tjp1b
tight junction protein 1b
chr17_+_24445818 1.28 ENSDART00000139963
ugp2b
UDP-glucose pyrophosphorylase 2b
chr1_-_45049603 1.25 ENSDART00000023336
rps6
ribosomal protein S6
chr15_-_32383529 1.24 ENSDART00000028349
c4
complement component 4
chr23_+_19691146 1.24 ENSDART00000143001
si:dkey-93l1.6
si:dkey-93l1.6
chr3_+_34180835 1.21 ENSDART00000055252
timm29
translocase of inner mitochondrial membrane 29
chr22_+_38194151 1.21 ENSDART00000121965
cp
ceruloplasmin
chr9_-_27771182 1.21 ENSDART00000170931
si:rp71-45g20.11
si:rp71-45g20.11
chr10_-_34915886 1.21 ENSDART00000141201
ENSDART00000002166
ccna1
cyclin A1
chr17_+_6765621 1.19 ENSDART00000156637
ENSDART00000007622
afg1la
AFG1 like ATPase a
chr7_+_19615056 1.19 ENSDART00000124752
ENSDART00000190297
si:ch211-212k18.15
si:ch211-212k18.15
chr10_+_36695597 1.19 ENSDART00000169015
ENSDART00000171392
rab6a
RAB6A, member RAS oncogene family
chr21_+_13577227 1.19 ENSDART00000146283
si:dkey-248f6.3
si:dkey-248f6.3
chr19_-_29832876 1.18 ENSDART00000005119
eif3i
eukaryotic translation initiation factor 3, subunit I
chr17_+_24446533 1.18 ENSDART00000131417
ugp2b
UDP-glucose pyrophosphorylase 2b
chr12_-_2869565 1.18 ENSDART00000152772
zdhhc16b
zinc finger, DHHC-type containing 16b
chr20_+_42537768 1.17 ENSDART00000134066
ENSDART00000153434
si:dkeyp-93d12.1
si:dkeyp-93d12.1
chr16_+_813780 1.17 ENSDART00000162474
ENSDART00000161774
irx1a
iroquois homeobox 1a
chr6_-_40195510 1.17 ENSDART00000156156
col7a1
collagen, type VII, alpha 1
chr6_+_47843760 1.15 ENSDART00000140943
padi2
peptidyl arginine deiminase, type II
chr16_-_46660680 1.15 ENSDART00000159209
ENSDART00000191929
tmem176l.4
transmembrane protein 176l.4
chr14_-_970853 1.14 ENSDART00000130801
acsl1b
acyl-CoA synthetase long chain family member 1b
chr18_+_7553950 1.13 ENSDART00000193420
ENSDART00000062143
zgc:77650
zgc:77650
chr6_+_23026714 1.10 ENSDART00000124948
srp68
signal recognition particle 68
chr25_-_1687481 1.09 ENSDART00000163553
ENSDART00000179460
mon2
MON2 homolog, regulator of endosome-to-Golgi trafficking
chr4_-_19693978 1.08 ENSDART00000100974
ENSDART00000040405
snd1
staphylococcal nuclease and tudor domain containing 1
chr10_+_11265387 1.08 ENSDART00000038888
hsdl2
hydroxysteroid dehydrogenase like 2
chr18_-_7481036 1.06 ENSDART00000101292
si:dkey-238c7.16
si:dkey-238c7.16
chr2_+_43920461 1.04 ENSDART00000123673
si:ch211-195h23.3
si:ch211-195h23.3
chr23_+_19182819 1.04 ENSDART00000131804
si:dkey-93l1.4
si:dkey-93l1.4
chr18_-_21746421 1.04 ENSDART00000188809
pskh1
protein serine kinase H1
chr23_-_19140781 1.03 ENSDART00000143580
si:ch73-381f5.2
si:ch73-381f5.2
chr23_+_309099 1.03 ENSDART00000134556
ENSDART00000055152
taf11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr17_-_45150763 1.02 ENSDART00000155043
ENSDART00000156786
ENSDART00000191147
tmed8
transmembrane p24 trafficking protein 8
chr8_-_24970790 1.01 ENSDART00000141267
si:ch211-199o1.2
si:ch211-199o1.2
chr23_+_10396842 1.01 ENSDART00000167593
ENSDART00000125103
eif4ba
eukaryotic translation initiation factor 4Ba
chr5_-_40210447 1.00 ENSDART00000131323
si:dkey-193c22.1
si:dkey-193c22.1
chr10_+_31646020 1.00 ENSDART00000115251
esama
endothelial cell adhesion molecule a
chr6_-_52348562 0.97 ENSDART00000142565
ENSDART00000145369
ENSDART00000016890
eif6
eukaryotic translation initiation factor 6
chr10_-_5857548 0.97 ENSDART00000166933
si:ch211-281k19.2
si:ch211-281k19.2
chr7_+_20503344 0.96 ENSDART00000157699
si:dkey-19b23.12
si:dkey-19b23.12
chr1_-_26292897 0.95 ENSDART00000112899
ENSDART00000185410
cxxc4
CXXC finger 4
chr11_+_2699951 0.95 ENSDART00000082512
tmem167b
transmembrane protein 167B
chr4_-_5913338 0.93 ENSDART00000183590
arl1
ADP-ribosylation factor-like 1
chr5_+_58550291 0.90 ENSDART00000184983
ENSDART00000044803
pou2f3
POU class 2 homeobox 3
chr17_+_22577472 0.89 ENSDART00000045099
yipf4
Yip1 domain family, member 4
chr20_-_30377221 0.88 ENSDART00000126229
rps7
ribosomal protein S7
chr6_-_35052388 0.87 ENSDART00000181000
ENSDART00000170116
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr7_+_31130667 0.87 ENSDART00000173937
tjp1a
tight junction protein 1a
chr9_-_28867562 0.86 ENSDART00000189597
ENSDART00000060321
zgc:91818
zgc:91818
chr5_+_20453874 0.86 ENSDART00000124545
ENSDART00000008402
sart3
squamous cell carcinoma antigen recognized by T cells 3
chr5_+_66220601 0.85 ENSDART00000129903
mfsd10
major facilitator superfamily domain containing 10
chr9_+_20526472 0.81 ENSDART00000166457
ENSDART00000141775
trim45
tripartite motif containing 45
chr12_-_35582683 0.80 ENSDART00000167933
sec24c
SEC24 homolog C, COPII coat complex component
chr17_-_15029639 0.79 ENSDART00000142941
ero1a
endoplasmic reticulum oxidoreductase alpha
chr15_-_14193659 0.79 ENSDART00000171197
pnkp
polynucleotide kinase 3'-phosphatase
chr4_-_5912951 0.75 ENSDART00000169439
arl1
ADP-ribosylation factor-like 1
chr6_-_40885496 0.74 ENSDART00000189857
sirt4
sirtuin 4
chr23_+_43638982 0.74 ENSDART00000168646
slc10a7
solute carrier family 10, member 7
chr19_-_35733401 0.73 ENSDART00000066712
trappc3
trafficking protein particle complex 3
chr6_-_54816567 0.73 ENSDART00000150079
tnni1b
troponin I type 1b (skeletal, slow)
chr1_-_27542119 0.72 ENSDART00000135759
si:ch211-127n13.2
si:ch211-127n13.2
chr21_-_8054977 0.72 ENSDART00000130508
si:dkey-163m14.4
si:dkey-163m14.4
chr15_+_41815703 0.71 ENSDART00000059508
pxylp1
2-phosphoxylose phosphatase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of xbp1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.7 GO:0051645 Golgi localization(GO:0051645)
1.8 12.4 GO:0006621 protein retention in ER lumen(GO:0006621)
1.2 5.9 GO:0006011 UDP-glucose metabolic process(GO:0006011)
1.1 3.4 GO:0042373 vitamin K metabolic process(GO:0042373)
1.1 3.3 GO:1905132 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
1.0 3.0 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
1.0 3.9 GO:0046951 ketone body biosynthetic process(GO:0046951)
1.0 2.9 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.9 2.7 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.8 8.4 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.8 5.0 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.7 3.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.6 1.9 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.4 5.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.4 2.2 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.4 1.3 GO:0016264 gap junction assembly(GO:0016264)
0.4 2.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.4 1.7 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.4 2.3 GO:0060876 semicircular canal formation(GO:0060876)
0.4 1.8 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.3 2.4 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.3 3.4 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.3 1.0 GO:0042256 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
0.3 4.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.3 6.7 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.3 2.2 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.3 15.0 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.3 1.4 GO:1990592 IRE1-mediated unfolded protein response(GO:0036498) negative regulation of response to endoplasmic reticulum stress(GO:1903573) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.3 0.9 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.3 10.7 GO:0030199 collagen fibril organization(GO:0030199)
0.3 2.7 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.3 3.4 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.3 2.3 GO:0090114 vesicle coating(GO:0006901) COPII-coated vesicle budding(GO:0090114)
0.2 1.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 1.7 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.2 1.2 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.2 7.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.2 1.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 2.2 GO:0045444 fat cell differentiation(GO:0045444)
0.2 2.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.2 5.8 GO:0001757 somite specification(GO:0001757)
0.2 2.6 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.2 4.9 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.2 3.0 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279) post-translational protein modification(GO:0043687)
0.2 1.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 2.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.2 0.6 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.2 3.6 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 2.8 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.1 0.7 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.1 2.4 GO:0060974 cell migration involved in heart formation(GO:0060974)
0.1 1.7 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1 3.0 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.1 3.9 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.1 2.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 2.7 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 2.5 GO:0015671 oxygen transport(GO:0015671)
0.1 1.4 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 2.7 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 0.7 GO:0050820 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 3.0 GO:0060872 semicircular canal development(GO:0060872)
0.1 0.3 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.1 1.0 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 1.9 GO:0097352 autophagosome maturation(GO:0097352)
0.1 1.0 GO:0070527 platelet aggregation(GO:0070527)
0.1 2.2 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 5.5 GO:0007030 Golgi organization(GO:0007030)
0.1 1.2 GO:0006825 copper ion transport(GO:0006825)
0.1 1.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 0.2 GO:0042823 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 0.4 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.4 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.0 2.5 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 2.1 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 1.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 1.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 1.7 GO:0051057 positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 3.0 GO:0051607 defense response to virus(GO:0051607)
0.0 1.2 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 2.1 GO:0006986 response to unfolded protein(GO:0006986)
0.0 1.5 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.2 GO:0007289 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 1.8 GO:0036269 swimming behavior(GO:0036269)
0.0 11.0 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.6 GO:0061055 myotome development(GO:0061055)
0.0 0.5 GO:0007530 sex determination(GO:0007530)
0.0 0.6 GO:0032438 melanosome organization(GO:0032438)
0.0 1.2 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 1.2 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.7 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 1.4 GO:0006956 complement activation(GO:0006956)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.2 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.9 GO:0001817 regulation of cytokine production(GO:0001817)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 6.7 GO:0007346 regulation of mitotic cell cycle(GO:0007346)
0.0 1.1 GO:0060048 cardiac muscle contraction(GO:0060048)
0.0 0.9 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 1.5 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.0 1.1 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.4 GO:0060840 artery development(GO:0060840)
0.0 0.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 2.7 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 23.3 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.9 3.6 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.7 4.9 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.7 3.4 GO:0018444 translation release factor complex(GO:0018444)
0.6 3.7 GO:0005784 Sec61 translocon complex(GO:0005784)
0.5 2.7 GO:0070390 transcription export complex 2(GO:0070390)
0.5 2.8 GO:0070876 SOSS complex(GO:0070876)
0.4 3.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.4 1.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.4 1.2 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.4 2.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.4 9.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.3 3.0 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.3 1.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.3 2.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3 12.8 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.3 2.3 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.2 2.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 1.8 GO:0071797 LUBAC complex(GO:0071797)
0.2 3.0 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.2 2.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 1.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.2 2.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 2.4 GO:0036038 MKS complex(GO:0036038)
0.1 2.5 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 3.7 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.7 GO:0016234 inclusion body(GO:0016234)
0.1 0.8 GO:0031526 brush border membrane(GO:0031526)
0.1 0.4 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 3.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 1.2 GO:0032039 integrator complex(GO:0032039)
0.1 0.9 GO:0015030 Cajal body(GO:0015030)
0.1 2.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.0 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 2.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 6.1 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 4.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 3.7 GO:0005581 collagen trimer(GO:0005581)
0.0 1.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 4.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 2.7 GO:0005871 kinesin complex(GO:0005871)
0.0 1.8 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 28.4 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 8.8 GO:0005730 nucleolus(GO:0005730)
0.0 8.9 GO:0000139 Golgi membrane(GO:0000139)
0.0 2.8 GO:0000776 kinetochore(GO:0000776)
0.0 1.1 GO:0005861 troponin complex(GO:0005861)
0.0 2.7 GO:0000786 nucleosome(GO:0000786)
0.0 9.0 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.2 GO:0030141 secretory granule(GO:0030141)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.4 GO:0046923 ER retention sequence binding(GO:0046923)
1.2 5.0 GO:0004475 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
1.2 5.9 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
1.1 2.1 GO:0070568 guanylyltransferase activity(GO:0070568)
1.0 3.9 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.7 3.0 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.7 3.5 GO:0008430 selenium binding(GO:0008430)
0.7 8.8 GO:0005537 mannose binding(GO:0005537)
0.7 3.9 GO:0051185 coenzyme transporter activity(GO:0051185)
0.6 2.9 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.5 2.4 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.5 1.4 GO:0071568 UFM1 transferase activity(GO:0071568)
0.5 2.3 GO:0030620 U2 snRNA binding(GO:0030620)
0.5 1.4 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.4 3.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.4 3.0 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.3 3.4 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.3 5.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.3 5.4 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.3 3.6 GO:0004526 ribonuclease P activity(GO:0004526)
0.3 4.0 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.3 0.8 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.2 6.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 1.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.2 2.5 GO:0031720 haptoglobin binding(GO:0031720)
0.2 1.5 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.2 2.7 GO:2001069 glycogen binding(GO:2001069)
0.2 2.6 GO:0051117 ATPase binding(GO:0051117)
0.2 6.7 GO:0005518 collagen binding(GO:0005518)
0.2 1.0 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.2 3.4 GO:0048038 quinone binding(GO:0048038)
0.2 2.7 GO:0046527 glucosyltransferase activity(GO:0046527)
0.1 1.0 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 1.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.6 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.9 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 1.4 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 1.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 2.9 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 1.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.6 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.6 GO:0019809 spermidine binding(GO:0019809)
0.1 1.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 2.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 3.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 1.0 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 4.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.7 GO:0070403 NAD+ binding(GO:0070403)
0.0 1.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 2.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 5.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 2.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0016504 peptidase activator activity(GO:0016504) lysine-acetylated histone binding(GO:0070577)
0.0 2.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.1 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.8 GO:0043130 ubiquitin binding(GO:0043130)
0.0 2.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 3.8 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 3.8 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 10.0 GO:0005198 structural molecule activity(GO:0005198)
0.0 4.2 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 2.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 5.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 2.1 GO:0042802 identical protein binding(GO:0042802)
0.0 10.8 GO:0008270 zinc ion binding(GO:0008270)
0.0 2.0 GO:0004497 monooxygenase activity(GO:0004497)
0.0 2.7 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 17.4 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 2.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 8.8 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 1.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 2.1 PID ARF 3PATHWAY Arf1 pathway
0.1 0.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 4.3 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 1.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.1 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 1.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 2.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 3.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.4 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.7 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.3 3.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 14.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.2 3.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 3.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 1.7 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 6.1 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.2 2.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 1.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 5.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.2 1.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 3.0 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 3.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 1.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 1.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 3.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 2.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 3.0 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.1 12.9 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 5.4 REACTOME INTERFERON SIGNALING Genes involved in Interferon Signaling
0.1 2.1 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.1 1.7 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 1.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.0 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network