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PRJEB1986: zebrafish developmental stages transcriptome

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Results for ybx1

Z-value: 0.57

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Transcription factors associated with ybx1

Gene Symbol Gene ID Gene Info
ybx1
ENSDARG00000004757 Y box binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ybx1dr11_v1_chr8_-_47152001_47152086-0.541.8e-02Click!

Activity profile of ybx1 motif

Sorted Z-values of ybx1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_+_44883805 7.51 ENSDART00000182805
si:ch73-361h17.1
si:ch73-361h17.1
chr2_-_42091926 2.78 ENSDART00000142663
si:dkey-97a13.12
si:dkey-97a13.12
chr20_-_52939501 2.26 ENSDART00000166508
fdft1
farnesyl-diphosphate farnesyltransferase 1
chr17_+_45305645 1.48 ENSDART00000172488
capn3a
calpain 3a, (p94)
chr25_-_4148719 1.24 ENSDART00000112880
ENSDART00000023278
fads2
fatty acid desaturase 2
chr1_-_20928772 1.22 ENSDART00000078277
msmo1
methylsterol monooxygenase 1
chr12_+_46960579 1.22 ENSDART00000149032
oat
ornithine aminotransferase
chr3_+_1167026 1.18 ENSDART00000031823
ENSDART00000155340
triobpb
TRIO and F-actin binding protein b
chr6_-_35446110 1.15 ENSDART00000058773
rgs16
regulator of G protein signaling 16
chr18_+_50089000 1.13 ENSDART00000058936
scamp5b
secretory carrier membrane protein 5b
chr25_-_19433244 1.06 ENSDART00000154778
map1ab
microtubule-associated protein 1Ab
chr6_-_48094342 1.03 ENSDART00000137458
slc2a1b
solute carrier family 2 (facilitated glucose transporter), member 1b
chr6_+_53349966 1.00 ENSDART00000167079
si:ch211-161c3.5
si:ch211-161c3.5
chr23_-_41651759 0.98 ENSDART00000146808
si:ch73-184c24.1
si:ch73-184c24.1
chr11_-_44543082 0.97 ENSDART00000099568
gpr137bb
G protein-coupled receptor 137Bb
chr18_+_907266 0.94 ENSDART00000171729
pkma
pyruvate kinase M1/2a
chr6_-_52156427 0.94 ENSDART00000082821
rims4
regulating synaptic membrane exocytosis 4
chr7_-_6466119 0.91 ENSDART00000173138
zgc:112234
zgc:112234
chr20_-_7176809 0.89 ENSDART00000012247
ENSDART00000125019
dhcr24
24-dehydrocholesterol reductase
chr10_+_44903676 0.89 ENSDART00000158553
zgc:114173
zgc:114173
chr21_-_5007109 0.89 ENSDART00000187042
ENSDART00000097796
ENSDART00000146766
rnf165a
ring finger protein 165a
chr2_-_4797512 0.89 ENSDART00000160765
tnk2b
tyrosine kinase, non-receptor, 2b
chr3_+_3810919 0.89 ENSDART00000056035
FQ311927.1

chr19_-_657439 0.88 ENSDART00000167100
slc6a18
solute carrier family 6 (neutral amino acid transporter), member 18
chr24_-_39772045 0.88 ENSDART00000087441
GFOD1
si:ch211-276f18.2
chr4_-_240737 0.86 ENSDART00000166186
RERG
si:cabz01085950.1
chr24_+_7631797 0.86 ENSDART00000187464
cavin1b
caveolae associated protein 1b
chr8_+_54081819 0.85 ENSDART00000005857
ENSDART00000161795
prickle2a
prickle homolog 2a
chr18_+_660578 0.83 ENSDART00000161203
CELF6
si:dkey-205h23.2
chr13_-_856525 0.83 ENSDART00000143356
TMEM14A
zgc:163080
chr24_+_24923166 0.81 ENSDART00000065288
pcyt1ba
phosphate cytidylyltransferase 1, choline, beta a
chr3_-_13147310 0.78 ENSDART00000160840
prkar1b
protein kinase, cAMP-dependent, regulatory, type I, beta
chr5_+_5398966 0.76 ENSDART00000139553
mapkap1
mitogen-activated protein kinase associated protein 1
chr23_+_2778813 0.76 ENSDART00000142621
top1
DNA topoisomerase I
chr9_+_27411502 0.75 ENSDART00000143994
si:dkey-193n17.9
si:dkey-193n17.9
chr19_-_6134802 0.75 ENSDART00000140051
cica
capicua transcriptional repressor a
chr7_+_38529263 0.75 ENSDART00000109495
ENSDART00000173804
nudt19
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr21_-_26406244 0.74 ENSDART00000137312
ENSDART00000077200
eif4ebp3
eukaryotic translation initiation factor 4E binding protein 3
chr10_+_6010570 0.74 ENSDART00000190025
ENSDART00000163680
hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr12_+_1469090 0.74 ENSDART00000183637
usp22
ubiquitin specific peptidase 22
chr23_-_35483163 0.73 ENSDART00000138660
ENSDART00000113643
ENSDART00000189269
fbxo25
F-box protein 25
chr23_+_19564392 0.73 ENSDART00000144746
atp6ap1lb
ATPase H+ transporting accessory protein 1 like b
chr20_-_53366137 0.71 ENSDART00000146001
wasf1
WAS protein family, member 1
chr13_-_856701 0.71 ENSDART00000140423
TMEM14A
zgc:163080
chr10_+_22782522 0.69 ENSDART00000079498
ENSDART00000145558
si:ch211-237l4.6
si:ch211-237l4.6
chr4_+_11375894 0.69 ENSDART00000190471
ENSDART00000143963
pcloa
piccolo presynaptic cytomatrix protein a
chr6_+_37752781 0.67 ENSDART00000154364
herc2
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr9_-_30145080 0.66 ENSDART00000133746
abi3bpa
ABI family, member 3 (NESH) binding protein a
chr15_-_3094516 0.66 ENSDART00000179719
slitrk5a
SLIT and NTRK-like family, member 5a
chr5_+_20030414 0.65 ENSDART00000181430
ENSDART00000047841
ENSDART00000182813
sgsm1a
small G protein signaling modulator 1a
chr3_-_61218272 0.64 ENSDART00000133091
ENSDART00000055068
pvalb5
parvalbumin 5
chr24_-_41220538 0.63 ENSDART00000150207
acvr2ba
activin A receptor type 2Ba
chr13_+_22264914 0.62 ENSDART00000060576
myoz1a
myozenin 1a
chr25_+_4541211 0.62 ENSDART00000129978
pnpla2
patatin-like phospholipase domain containing 2
chr21_+_3897680 0.61 ENSDART00000170653
dolpp1
dolichyldiphosphatase 1
chr24_-_24271629 0.61 ENSDART00000135060
rps6ka3b
ribosomal protein S6 kinase, polypeptide 3b
chr7_+_1521834 0.61 ENSDART00000174007
si:cabz01102082.1
si:cabz01102082.1
chr10_-_35236949 0.60 ENSDART00000145804
ypel2a
yippee-like 2a
chr4_-_28158335 0.59 ENSDART00000134605
gramd4a
GRAM domain containing 4a
chr19_+_42806812 0.58 ENSDART00000108775
ENSDART00000151653
ubp1
upstream binding protein 1
chr21_-_293146 0.57 ENSDART00000157781
plgrkt
plasminogen receptor, C-terminal lysine transmembrane protein
chr15_+_1148074 0.57 ENSDART00000152638
ENSDART00000152466
ENSDART00000188011
mlf1
myeloid leukemia factor 1
chr14_+_3038473 0.56 ENSDART00000026021
ENSDART00000150000
cd74a
CD74 molecule, major histocompatibility complex, class II invariant chain a
chr8_-_1219815 0.56 ENSDART00000016800
ENSDART00000149969
znf367
zinc finger protein 367
chr13_-_3370638 0.54 ENSDART00000029649
prkn
parkin RBR E3 ubiquitin protein ligase
chr21_+_5888641 0.53 ENSDART00000091331
prodha
proline dehydrogenase (oxidase) 1a
chr16_+_68069 0.53 ENSDART00000185385
ENSDART00000159652
sox4b
SRY (sex determining region Y)-box 4b
chr7_+_5906327 0.52 ENSDART00000173160
zgc:112234
zgc:112234
chr3_+_36541003 0.52 ENSDART00000164514
si:dkeyp-72e1.9
si:dkeyp-72e1.9
chr15_+_43166511 0.51 ENSDART00000011737
flj13639
flj13639
chr16_+_45930962 0.50 ENSDART00000124689
ENSDART00000041811
otud7b
OTU deubiquitinase 7B
chr18_+_27515640 0.50 ENSDART00000181593
tp53i11b
tumor protein p53 inducible protein 11b
chr15_-_19250543 0.48 ENSDART00000092705
ENSDART00000138895
igsf9ba
immunoglobulin superfamily, member 9Ba
chr25_+_10458990 0.48 ENSDART00000130354
ENSDART00000044738
ric8a
RIC8 guanine nucleotide exchange factor A
chr25_-_35542739 0.47 ENSDART00000097651
si:ch211-87j1.4
si:ch211-87j1.4
chr17_-_43286903 0.47 ENSDART00000176637
EML5
si:dkey-1f12.3
chr22_+_17205608 0.47 ENSDART00000181267
rab3b
RAB3B, member RAS oncogene family
chr12_+_40905427 0.47 ENSDART00000170526
ENSDART00000185771
ENSDART00000193945
CDH18
cadherin 18
chr9_-_2572790 0.46 ENSDART00000135076
ENSDART00000016710
scrn3
secernin 3
chr4_-_76370630 0.46 ENSDART00000168831
ENSDART00000174313
si:ch73-158p21.3
si:ch73-158p21.3
chr7_-_6364168 0.46 ENSDART00000173332
zgc:112234
zgc:112234
chr11_-_42554290 0.46 ENSDART00000130573
atp6ap1la
ATPase H+ transporting accessory protein 1 like a
chr8_-_44015210 0.45 ENSDART00000186879
ENSDART00000188965
ENSDART00000001313
ENSDART00000188902
ENSDART00000185935
ENSDART00000147869
rimbp2
rimbp2
RIMS binding protein 2
RIMS binding protein 2
chr9_+_45227028 0.44 ENSDART00000185579
adarb1b
adenosine deaminase, RNA-specific, B1b
chr11_+_77526 0.44 ENSDART00000193521
CABZ01072242.1

chr18_-_26894732 0.44 ENSDART00000147735
ENSDART00000188938
BX470164.1
si:dkey-24l11.2

si:dkey-24l11.2
chr12_+_1469327 0.44 ENSDART00000059143
usp22
ubiquitin specific peptidase 22
chr25_-_35150933 0.44 ENSDART00000129254
HIST2H3C
zgc:173552
chr13_-_36050303 0.43 ENSDART00000134955
ENSDART00000139087
lgmn
legumain
chr2_-_58193381 0.43 ENSDART00000159040
pnp5b
purine nucleoside phosphorylase 5b
chr17_-_6514962 0.43 ENSDART00000163514
dnajc5gb
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma b
chr15_-_47336811 0.43 ENSDART00000182730
anapc15
anaphase promoting complex subunit 15
chr7_-_69636502 0.42 ENSDART00000126739
tspan5a
tetraspanin 5a
chr10_-_15644904 0.42 ENSDART00000138389
ENSDART00000101191
ENSDART00000186559
ENSDART00000122170
smc5
structural maintenance of chromosomes 5
chr16_+_46695777 0.42 ENSDART00000169767
rab25b
RAB25, member RAS oncogene family b
chr24_-_21404367 0.41 ENSDART00000152093
atp8a2
ATPase phospholipid transporting 8A2
chr23_+_14590767 0.41 ENSDART00000143675
si:rp71-79p20.2
si:rp71-79p20.2
chr19_-_1855368 0.40 ENSDART00000029646
rplp1
ribosomal protein, large, P1
chr9_+_22677503 0.40 ENSDART00000131429
ENSDART00000080005
ENSDART00000101756
ENSDART00000138148
itgb5
integrin, beta 5
chr7_-_73834812 0.40 ENSDART00000128137
zgc:92594
zgc:92594
chr14_-_12071447 0.38 ENSDART00000166116
tmsb1
thymosin beta 1
chr19_-_30562648 0.37 ENSDART00000171006
hpcal4
hippocalcin like 4
chr9_-_2573121 0.37 ENSDART00000181340
scrn3
secernin 3
chr23_+_14590483 0.37 ENSDART00000088359
ENSDART00000184868
si:rp71-79p20.2
si:rp71-79p20.2
chr20_-_40487208 0.36 ENSDART00000075070
ENSDART00000142029
hsf2
heat shock transcription factor 2
chr2_+_24867534 0.36 ENSDART00000158050
rab3aa
RAB3A, member RAS oncogene family, a
chr2_+_47708853 0.36 ENSDART00000124307
mbnl1
muscleblind-like splicing regulator 1
chr3_-_58543658 0.35 ENSDART00000042386
unm_sa1261
un-named sa1261
chr6_-_218882 0.34 ENSDART00000008398
c1qtnf6b
C1q and TNF related 6b
chr22_-_11493236 0.34 ENSDART00000002691
tspan7b
tetraspanin 7b
chr16_+_4838808 0.34 ENSDART00000179363
ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr3_-_10751491 0.34 ENSDART00000016351
zgc:112965
zgc:112965
chr20_+_16743056 0.34 ENSDART00000050308
calm1b
calmodulin 1b
chr23_+_6795531 0.34 ENSDART00000092131
si:ch211-117c9.5
si:ch211-117c9.5
chr1_+_6817292 0.34 ENSDART00000145822
ENSDART00000092118
erbb4a
erb-b2 receptor tyrosine kinase 4a
chr22_+_38173960 0.33 ENSDART00000010537
cp
ceruloplasmin
chr21_+_944715 0.32 ENSDART00000144766
nars
asparaginyl-tRNA synthetase
chr14_-_40821411 0.32 ENSDART00000166621
elf1
E74-like ETS transcription factor 1
chr5_+_45138934 0.31 ENSDART00000041412
ENSDART00000136002
smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_+_2499627 0.30 ENSDART00000160782
wipf1a
WAS/WASL interacting protein family, member 1a
chr25_-_35110695 0.30 ENSDART00000099859
hist1h2a10
histone cluster 1 H2A family member 10
chr21_+_244503 0.29 ENSDART00000162889
stard4
StAR-related lipid transfer (START) domain containing 4
chr18_-_49116382 0.29 ENSDART00000174157
BX663503.3

chr8_+_36288261 0.29 ENSDART00000191281
CU929676.1

chr10_-_7858553 0.29 ENSDART00000182010
inpp5ja
inositol polyphosphate-5-phosphatase Ja
chr19_-_43004356 0.28 ENSDART00000098101
zcchc17
zinc finger, CCHC domain containing 17
chr22_+_30543437 0.28 ENSDART00000137983
si:dkey-103k4.1
si:dkey-103k4.1
chr2_+_37480669 0.28 ENSDART00000029801
sppl2
signal peptide peptidase-like 2
chr7_-_13884610 0.27 ENSDART00000006897
rlbp1a
retinaldehyde binding protein 1a
chr24_+_7708652 0.27 ENSDART00000066816
btr33
bloodthirsty-related gene family, member 33
chr3_-_8765165 0.27 ENSDART00000191131
CABZ01058333.1

chr6_+_3710865 0.26 ENSDART00000170781
phospho2
phosphatase, orphan 2
chr20_-_49889111 0.26 ENSDART00000058858
kif13bb
kinesin family member 13Bb
chr23_+_45579497 0.26 ENSDART00000110381
egr4
early growth response 4
chr13_+_2394534 0.26 ENSDART00000172535
ENSDART00000006990
elovl5
ELOVL fatty acid elongase 5
chr15_+_25439106 0.25 ENSDART00000156252
aifm4
apoptosis-inducing factor, mitochondrion-associated, 4
chr5_-_16983336 0.24 ENSDART00000038740
galnt9
polypeptide N-acetylgalactosaminyltransferase 9
chr18_-_2549198 0.24 ENSDART00000186516
CABZ01070631.1

chr6_+_52350443 0.24 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
si:ch211-239j9.1
chr19_+_770300 0.24 ENSDART00000062518
gstr
glutathione S-transferase rho
chr1_+_25801648 0.24 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr5_+_45139196 0.24 ENSDART00000113738
smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr20_-_3403033 0.23 ENSDART00000092264
rev3l
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr15_+_25438714 0.23 ENSDART00000154164
aifm4
apoptosis-inducing factor, mitochondrion-associated, 4
chr2_+_24868010 0.23 ENSDART00000078838
rab3aa
RAB3A, member RAS oncogene family, a
chr7_-_6431158 0.22 ENSDART00000173199
si:ch1073-153i20.5
si:ch1073-153i20.5
chr1_+_1599979 0.22 ENSDART00000097626
urp2
urotensin II-related peptide
chr7_+_16033923 0.21 ENSDART00000161669
ENSDART00000114062
immp1l
inner mitochondrial membrane peptidase subunit 1
chr3_+_62353650 0.21 ENSDART00000112428
iqck
IQ motif containing K
chr24_+_34606966 0.21 ENSDART00000105477
lrrtm2
leucine rich repeat transmembrane neuronal 2
chr18_+_2563756 0.21 ENSDART00000164147
p2ry2.1
purinergic receptor P2Y2, tandem duplicate 1
chr22_-_4407871 0.21 ENSDART00000162523
kdm4b
lysine (K)-specific demethylase 4B
chr3_+_59051503 0.21 ENSDART00000160767
rasd4
rasd family member 4
chr16_-_44349845 0.20 ENSDART00000170932
rims2a
regulating synaptic membrane exocytosis 2a
chr12_-_48671612 0.20 ENSDART00000007202
zgc:92749
zgc:92749
chr7_+_5905091 0.20 ENSDART00000167099
CU459186.3
Histone H3.2
chr2_+_9946121 0.19 ENSDART00000100696
tsen15
TSEN15 tRNA splicing endonuclease subunit
chr7_-_31794476 0.19 ENSDART00000142385
nap1l4b
nucleosome assembly protein 1-like 4b
chr2_-_51059691 0.19 ENSDART00000158131
ftr87
finTRIM family, member 87
chr5_+_36439405 0.19 ENSDART00000102973
eda
ectodysplasin A
chr15_+_26940569 0.18 ENSDART00000189636
ENSDART00000077172
bcas3
breast carcinoma amplified sequence 3
chr11_-_18604542 0.18 ENSDART00000171183
zmynd8
zinc finger, MYND-type containing 8
chr3_-_3328097 0.18 ENSDART00000193140
tmem184bb
transmembrane protein 184bb
chr11_-_18604317 0.18 ENSDART00000182081
zmynd8
zinc finger, MYND-type containing 8
chr7_-_29115772 0.17 ENSDART00000076386
fbxl8
F-box and leucine-rich repeat protein 8
chr14_+_1687357 0.16 ENSDART00000174675
hrh2a
histamine receptor H2a
chr11_+_45436703 0.16 ENSDART00000168295
ENSDART00000173293
sos1
son of sevenless homolog 1 (Drosophila)
chr23_-_4930229 0.16 ENSDART00000189456
ngfa
nerve growth factor a (beta polypeptide)
chr17_+_23556764 0.15 ENSDART00000146787
pank1a
pantothenate kinase 1a
chr1_+_12394205 0.15 ENSDART00000138622
ENSDART00000136421
ENSDART00000139440
ENSDART00000184296
ENSDART00000008127
zgc:77739
zgc:77739
chr8_-_11146687 0.15 ENSDART00000189626
asb13b
ankyrin repeat and SOCS box containing 13b
chr17_+_6382275 0.15 ENSDART00000056324
CR628323.2

chr5_-_68074592 0.15 ENSDART00000165052
ENSDART00000018792
spag7
sperm associated antigen 7
chr7_-_73845736 0.15 ENSDART00000193414
zgc:173552
zgc:173552
chr7_+_5910467 0.14 ENSDART00000173232
si:ch211-113a14.22
si:ch211-113a14.22
chr18_+_44795711 0.14 ENSDART00000110229
ENSDART00000188262
ENSDART00000139526
fam118b
family with sequence similarity 118, member B
chr8_+_53269657 0.14 ENSDART00000184212
gnb1a
guanine nucleotide binding protein (G protein), beta polypeptide 1a
chr3_-_62403550 0.14 ENSDART00000055055
sox8b
SRY (sex determining region Y)-box 8b
chr20_+_21391181 0.14 ENSDART00000185158
ENSDART00000049586
ENSDART00000024922
jag2b
jagged 2b
chr19_+_2619444 0.14 ENSDART00000169483
fam126a
family with sequence similarity 126, member A
chr1_-_9644630 0.14 ENSDART00000123725
ENSDART00000161164
ugt5b3
UDP glucuronosyltransferase 5 family, polypeptide B3
chr8_-_39884359 0.14 ENSDART00000131372
mlec
malectin
chr7_-_18617187 0.13 ENSDART00000172419
si:ch211-119e14.1
si:ch211-119e14.1
chr18_+_21273749 0.13 ENSDART00000143265
hydin
HYDIN, axonemal central pair apparatus protein
chr23_+_37185247 0.11 ENSDART00000146269
vwa5b1
von Willebrand factor A domain containing 5B1
chr7_+_5976613 0.11 ENSDART00000173105
si:dkey-23a13.21
si:dkey-23a13.21
chr5_-_2721686 0.10 ENSDART00000169404
hspa5
heat shock protein 5
chr2_-_25120197 0.10 ENSDART00000132549
pccb
propionyl CoA carboxylase, beta polypeptide
chr19_+_5640504 0.10 ENSDART00000179987
ft2
alpha(1,3)fucosyltransferase gene 2
chr23_-_2037566 0.09 ENSDART00000191312
ENSDART00000127443
prdm5
PR domain containing 5
chr1_-_54063520 0.09 ENSDART00000171722
smdt1b
single-pass membrane protein with aspartate-rich tail 1b
chr6_+_2951645 0.09 ENSDART00000183181
ENSDART00000181271
ptprfa
protein tyrosine phosphatase, receptor type, f, a
chr11_+_440305 0.09 ENSDART00000082517
rab43
RAB43, member RAS oncogene family
chr6_+_102506 0.08 ENSDART00000172678
ldlrb
low density lipoprotein receptor b
chr7_+_17953589 0.08 ENSDART00000174778
ENSDART00000113120
taf6l
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr14_-_30945515 0.08 ENSDART00000161540
si:zfos-80g12.1
si:zfos-80g12.1
chr3_-_3327573 0.08 ENSDART00000136319
ENSDART00000166667
tmem184bb
transmembrane protein 184bb
chr11_-_15297129 0.08 ENSDART00000167985
ENSDART00000163031
ENSDART00000165010
ENSDART00000171250
ENSDART00000010684
ENSDART00000191714
ENSDART00000191164
rpn2
ribophorin II
chr19_+_791538 0.07 ENSDART00000146554
ENSDART00000138406
tmem79a
transmembrane protein 79a
chr15_-_19677511 0.07 ENSDART00000043743
si:dkey-4p15.3
si:dkey-4p15.3

Network of associatons between targets according to the STRING database.

First level regulatory network of ybx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.0 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.3 1.0 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.2 0.6 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.2 0.6 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.2 0.6 GO:0010935 dendritic cell antigen processing and presentation(GO:0002468) macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.2 0.6 GO:0010896 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.6 GO:0034164 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 1.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.6 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.1 0.4 GO:0090266 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 1.2 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.8 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952) mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 0.4 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.9 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.1 0.5 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.5 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.7 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 0.3 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.1 0.7 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.2 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.1 0.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.5 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.1 0.2 GO:0070255 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.1 1.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.2 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.5 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 1.1 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.6 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.4 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.3 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.0 0.3 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 1.3 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 1.5 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.8 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 1.2 GO:0030641 regulation of cellular pH(GO:0030641)
0.0 0.5 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.3 GO:0006825 copper ion transport(GO:0006825)
0.0 0.9 GO:0006096 glycolytic process(GO:0006096)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.4 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 0.3 GO:0043489 RNA stabilization(GO:0043489)
0.0 0.5 GO:0032924 activin receptor signaling pathway(GO:0032924)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.3 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.7 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 0.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 1.1 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.6 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.0 0.9 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.5 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.6 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.2 0.7 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.2 0.9 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 1.2 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.2 0.8 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.2 0.8 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 0.9 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 1.0 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.5 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.6 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 0.8 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 1.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 1.2 GO:0008483 transaminase activity(GO:0008483)
0.0 0.6 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.7 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.9 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.6 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.6 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0004061 arylformamidase activity(GO:0004061)
0.0 0.3 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.8 GO:0044325 ion channel binding(GO:0044325)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.2 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones