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PRJEB1986: zebrafish developmental stages transcriptome

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Results for zbtb18+zbtb42

Z-value: 1.00

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Transcription factors associated with zbtb18+zbtb42

Gene Symbol Gene ID Gene Info
zbtb18
ENSDARG00000028228 zinc finger and BTB domain containing 18
zbtb42
ENSDARG00000102761 zinc finger and BTB domain containing 42

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zbtb18dr11_v1_chr13_+_11436130_11436130-0.571.1e-02Click!
zbtb42dr11_v1_chr17_-_1407593_14077250.483.7e-02Click!

Activity profile of zbtb18+zbtb42 motif

Sorted Z-values of zbtb18+zbtb42 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_25226558 4.50 ENSDART00000168480
sycn.2
syncollin, tandem duplicate 2
chr8_-_25247284 4.01 ENSDART00000132697
gnat2
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr24_-_26282672 3.85 ENSDART00000176663
and1
actinodin1
chr18_+_45550783 3.76 ENSDART00000138075
kifc3
kinesin family member C3
chr18_-_46241775 3.24 ENSDART00000145999
ENSDART00000134244
ENSDART00000185021
ENSDART00000181855
prx
periaxin
chr15_-_30816370 3.01 ENSDART00000142982
ENSDART00000050649
ENSDART00000136901
ENSDART00000100194
msi2b
musashi RNA-binding protein 2b
chr6_+_612594 2.90 ENSDART00000150903
kynu
kynureninase
chr3_-_53486169 2.75 ENSDART00000115243
soul5
heme-binding protein soul5
chr18_-_21097663 2.74 ENSDART00000060196
anpepa
alanyl (membrane) aminopeptidase a
chr21_+_25216397 2.70 ENSDART00000130970
sycn.3
syncollin, tandem duplicate 3
chr1_+_45351890 2.52 ENSDART00000145486
si:ch211-243a20.3
si:ch211-243a20.3
chr3_+_15296824 2.41 ENSDART00000043801
cabp5b
calcium binding protein 5b
chr19_-_44091405 2.39 ENSDART00000132800
rad21b
RAD21 cohesin complex component b
chr20_+_23238833 2.34 ENSDART00000074167
ociad2
OCIA domain containing 2
chr25_+_31277415 2.27 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr1_-_22370660 2.23 ENSDART00000127506
si:ch73-380n15.2
si:ch73-380n15.2
chr21_+_18313152 2.20 ENSDART00000170510
si:ch73-287m6.1
si:ch73-287m6.1
chr10_+_21737745 2.15 ENSDART00000170498
ENSDART00000167997
pcdh1g18
protocadherin 1 gamma 18
chr1_-_21409877 2.14 ENSDART00000102782
gria2a
glutamate receptor, ionotropic, AMPA 2a
chr11_-_24681292 2.12 ENSDART00000089601
olfml3b
olfactomedin-like 3b
chr2_+_39021282 2.07 ENSDART00000056577
RBP1 (1 of many)
si:ch211-119o8.7
chr9_+_1162216 2.04 ENSDART00000165295
stk24a
serine/threonine kinase 24a (STE20 homolog, yeast)
chr25_+_31276842 2.02 ENSDART00000187238
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr7_-_38612230 1.98 ENSDART00000173678
c1qtnf4
C1q and TNF related 4
chr17_-_20287530 1.95 ENSDART00000078703
ENSDART00000191289
add3b
adducin 3 (gamma) b
chr5_-_30145939 1.94 ENSDART00000086795
zbtb44
zinc finger and BTB domain containing 44
chr3_+_44947355 1.94 ENSDART00000083040
hs3st2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr10_-_24371312 1.93 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr24_-_28243186 1.91 ENSDART00000105691
cox4i1l
cytochrome c oxidase subunit IV isoform 1, like
chr6_+_22597362 1.89 ENSDART00000131242
cygb2
cytoglobin 2
chr2_-_51634431 1.86 ENSDART00000165568
pigr
polymeric immunoglobulin receptor
chr20_+_50852356 1.85 ENSDART00000167517
ENSDART00000168396
gphnb
gephyrin b
chr25_-_7974494 1.70 ENSDART00000171446
hal
histidine ammonia-lyase
chr5_-_23429228 1.69 ENSDART00000049291
gria3a
glutamate receptor, ionotropic, AMPA 3a
chr12_+_27704015 1.68 ENSDART00000153256
cacna1g
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr9_+_7456076 1.66 ENSDART00000125824
ENSDART00000122526
tmem198a
transmembrane protein 198a
chr25_+_15841670 1.63 ENSDART00000049992
syt9b
synaptotagmin IXb
chr16_+_21738194 1.62 ENSDART00000163688
FP085428.1
Danio rerio si:ch211-154o6.4 (si:ch211-154o6.4), mRNA.
chr20_+_29587995 1.61 ENSDART00000153339
adam17b
ADAM metallopeptidase domain 17b
chr7_+_17229282 1.58 ENSDART00000097982
slc6a5
solute carrier family 6 (neurotransmitter transporter), member 5
chr18_+_17660402 1.56 ENSDART00000143475
cpne2
copine II
chr19_+_47311020 1.55 ENSDART00000138295
ext1c
exostoses (multiple) 1c
chr2_+_26647472 1.54 ENSDART00000145415
ENSDART00000157409
ttpa
tocopherol (alpha) transfer protein
chr23_+_45229198 1.53 ENSDART00000172445
ttc39b
tetratricopeptide repeat domain 39B
chr5_+_19309877 1.49 ENSDART00000190338
rusc2
RUN and SH3 domain containing 2
chr20_+_2460864 1.47 ENSDART00000131642
akap7
A kinase (PRKA) anchor protein 7
chr19_+_47299212 1.46 ENSDART00000158262
tpmt.1
thiopurine S-methyltransferase, tandem duplicate 1
chr10_-_15128771 1.46 ENSDART00000101261
spp1
secreted phosphoprotein 1
chr11_-_37411492 1.45 ENSDART00000166468
erc2
ELKS/RAB6-interacting/CAST family member 2
chr10_-_29903165 1.45 ENSDART00000078800
lim2.1
lens intrinsic membrane protein 2.1
chr8_+_8735285 1.43 ENSDART00000165655
elk1
ELK1, member of ETS oncogene family
chr19_-_8732037 1.43 ENSDART00000138971
si:ch211-39a7.1
si:ch211-39a7.1
chr1_+_157793 1.40 ENSDART00000152205
cul4a
cullin 4A
chr17_-_19344999 1.39 ENSDART00000138315
gsc
goosecoid
chr5_+_31480342 1.38 ENSDART00000098197
si:dkey-220k22.1
si:dkey-220k22.1
chr2_-_37043905 1.38 ENSDART00000056514
gng7
guanine nucleotide binding protein (G protein), gamma 7
chr12_-_26383242 1.36 ENSDART00000152941
usp54b
ubiquitin specific peptidase 54b
chr9_-_38587275 1.36 ENSDART00000077446
si:dkey-101k6.5
si:dkey-101k6.5
chr18_+_402048 1.30 ENSDART00000166345
gpib
glucose-6-phosphate isomerase b
chr12_-_18519822 1.29 ENSDART00000152780
tex2l
testis expressed 2, like
chr23_-_36857964 1.28 ENSDART00000188822
ENSDART00000134061
ENSDART00000093061
hipk1a
homeodomain interacting protein kinase 1a
chr19_-_3482138 1.27 ENSDART00000168139
hivep1
human immunodeficiency virus type I enhancer binding protein 1
chr7_+_17229980 1.27 ENSDART00000184910
slc6a5
solute carrier family 6 (neurotransmitter transporter), member 5
chr4_+_12612723 1.27 ENSDART00000133767
lmo3
LIM domain only 3
chr15_-_30815826 1.26 ENSDART00000156160
ENSDART00000145918
msi2b
musashi RNA-binding protein 2b
chr20_-_8443425 1.26 ENSDART00000083908
dab1a
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr20_-_40451115 1.25 ENSDART00000075092
pkib
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr9_+_33009284 1.24 ENSDART00000036926
vangl1
VANGL planar cell polarity protein 1
chr5_+_69981453 1.24 ENSDART00000143860
si:ch211-154e10.1
si:ch211-154e10.1
chr12_-_7806007 1.20 ENSDART00000190359
ank3b
ankyrin 3b
chr1_-_7917062 1.16 ENSDART00000177068
mmd2b
monocyte to macrophage differentiation-associated 2b
chr19_+_22216778 1.16 ENSDART00000052521
nfatc1
nuclear factor of activated T cells 1
chr7_-_71837213 1.15 ENSDART00000168645
ENSDART00000160512
cacnb2a
calcium channel, voltage-dependent, beta 2a
chr20_+_16750177 1.15 ENSDART00000185357
calm1b
calmodulin 1b
chr21_-_19006631 1.14 ENSDART00000080269
ENSDART00000191682
pgam2
phosphoglycerate mutase 2 (muscle)
chr12_+_20699534 1.14 ENSDART00000131883
si:ch211-119c20.2
si:ch211-119c20.2
chr15_-_14552101 1.13 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr18_+_17660158 1.13 ENSDART00000186279
cpne2
copine II
chr16_+_2843428 1.13 ENSDART00000149485
clec3ba
C-type lectin domain family 3, member Ba
chr5_-_33769211 1.11 ENSDART00000133504
dab2ipb
DAB2 interacting protein b
chr12_+_24344963 1.09 ENSDART00000191648
ENSDART00000183180
ENSDART00000088178
ENSDART00000189696
nrxn1a
neurexin 1a
chr15_+_30158652 1.09 ENSDART00000190682
nlk2
nemo-like kinase, type 2
chr8_+_25247245 1.09 ENSDART00000045798
ampd2b
adenosine monophosphate deaminase 2b
chr25_-_19661198 1.07 ENSDART00000149641
atp2b1b
ATPase plasma membrane Ca2+ transporting 1b
chr23_+_40604951 1.07 ENSDART00000114959
cdh24a
cadherin 24, type 2a
chr2_-_24603325 1.05 ENSDART00000113356
crtc1a
CREB regulated transcription coactivator 1a
chr21_-_33995213 1.03 ENSDART00000140184
EBF1 (1 of many)
si:ch211-51e8.2
chr10_+_24445698 1.03 ENSDART00000146370
slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr11_-_28157129 1.01 ENSDART00000103450
lactbl1b
lactamase, beta-like 1b
chr24_-_28245872 1.01 ENSDART00000167861
cox4i1l
cytochrome c oxidase subunit IV isoform 1, like
chr13_+_12045475 0.99 ENSDART00000163053
ENSDART00000160812
ENSDART00000158244
gng2
guanine nucleotide binding protein (G protein), gamma 2
chr16_+_45424907 0.99 ENSDART00000134471
phf1
PHD finger protein 1
chr7_+_29133321 0.98 ENSDART00000052346
gnao1b
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b
chr20_-_14875308 0.98 ENSDART00000141290
dnm3a
dynamin 3a
chr3_+_431208 0.97 ENSDART00000154296
ENSDART00000048733
si:ch73-308m11.1
si:dkey-167k11.5
si:ch73-308m11.1
si:dkey-167k11.5
chr3_+_33367954 0.97 ENSDART00000103161
mpp2a
membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2)
chr12_+_2660733 0.95 ENSDART00000152235
irbpl
interphotoreceptor retinoid-binding protein like
chr19_-_40776267 0.94 ENSDART00000189038
calcr
calcitonin receptor
chr20_-_47704973 0.94 ENSDART00000174808
tfap2b
transcription factor AP-2 beta
chr3_+_17846890 0.92 ENSDART00000193384
znf385c
zinc finger protein 385C
chr17_+_8275711 0.91 ENSDART00000128105
si:ch211-236p5.2
si:ch211-236p5.2
chr5_+_19314574 0.90 ENSDART00000133247
rusc2
RUN and SH3 domain containing 2
chr7_-_41403022 0.90 ENSDART00000174285
BX322787.1

chr7_-_51627019 0.89 ENSDART00000174111
nhsl2
NHS-like 2
chr20_-_9278252 0.88 ENSDART00000136079
syt14b
synaptotagmin XIVb
chr10_+_40836378 0.88 ENSDART00000085792
trim69
tripartite motif containing 69
chr20_+_7209972 0.87 ENSDART00000189169
ENSDART00000136974
si:dkeyp-51f12.3
si:dkeyp-51f12.3
chr16_+_30117798 0.86 ENSDART00000135723
ENSDART00000000198
sema6e
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E
chr14_+_30910114 0.86 ENSDART00000187166
ENSDART00000078187
foxo4
forkhead box O4
chr1_+_31864404 0.85 ENSDART00000075260
inab
internexin neuronal intermediate filament protein, alpha b
chr19_+_7627070 0.84 ENSDART00000151078
ENSDART00000131324
pygo2
pygopus homolog 2 (Drosophila)
chr24_-_39826865 0.82 ENSDART00000089232
slc12a7b
solute carrier family 12 (potassium/chloride transporter), member 7b
chr6_-_13308813 0.80 ENSDART00000065372
kcnj3b
potassium inwardly-rectifying channel, subfamily J, member 3b
chr22_-_6884981 0.79 ENSDART00000124219
FO904898.4

chr6_-_10320676 0.79 ENSDART00000151247
scn1lab
sodium channel, voltage-gated, type I like, alpha b
chr13_+_25422009 0.79 ENSDART00000057686
calhm2
calcium homeostasis modulator 2
chr7_+_50109239 0.78 ENSDART00000021605
LRRC4C (1 of many)
si:dkey-6l15.1
chr3_+_32129632 0.78 ENSDART00000174522
zgc:109934
zgc:109934
chr24_-_982443 0.77 ENSDART00000063151
napga
N-ethylmaleimide-sensitive factor attachment protein, gamma a
chr12_-_28881638 0.77 ENSDART00000148459
ENSDART00000039667
ENSDART00000148668
ENSDART00000136593
ENSDART00000139923
ENSDART00000148912
cbx1b
chromobox homolog 1b (HP1 beta homolog Drosophila)
chr6_+_612330 0.76 ENSDART00000166872
ENSDART00000191758
kynu
kynureninase
chr16_+_9609721 0.72 ENSDART00000047920
enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr20_+_14968031 0.71 ENSDART00000151805
ENSDART00000151448
ENSDART00000063874
ENSDART00000190910
vamp4
vesicle-associated membrane protein 4
chr8_-_17064243 0.71 ENSDART00000185313
rab3c
RAB3C, member RAS oncogene family
chr15_-_4314042 0.71 ENSDART00000173311
ENSDART00000170562
ECE2
si:ch211-117a13.2
chr5_-_39474235 0.71 ENSDART00000171557
antxr2a
anthrax toxin receptor 2a
chr20_+_27298783 0.70 ENSDART00000013861
ppp4r4
protein phosphatase 4, regulatory subunit 4
chr3_-_3731563 0.69 ENSDART00000180978
BX908804.2

chr8_+_19624589 0.69 ENSDART00000185698
slc35a3a
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr24_+_41610068 0.69 ENSDART00000159507
CABZ01044108.1

chr2_-_42705284 0.69 ENSDART00000187160
myo10
myosin X
chr19_-_24267823 0.69 ENSDART00000132430
s100v2
S100 calcium binding protein V2
chr9_-_12443726 0.68 ENSDART00000102434
ehhadh
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
chr21_+_25221940 0.67 ENSDART00000108972
sycn.1
syncollin, tandem duplicate 1
chr18_-_6982499 0.67 ENSDART00000101525
si:dkey-266m15.6
si:dkey-266m15.6
chr17_+_11507131 0.66 ENSDART00000013170
kif26ba
kinesin family member 26Ba
chr17_+_29345606 0.66 ENSDART00000086164
kctd3
potassium channel tetramerization domain containing 3
chr6_+_4299164 0.66 ENSDART00000159759
nbeal1
neurobeachin-like 1
chr13_+_25421531 0.64 ENSDART00000158093
calhm2
calcium homeostasis modulator 2
chr2_+_5793908 0.63 ENSDART00000145219
slc35d1b
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1b
chr9_+_17787864 0.62 ENSDART00000013111
dgkh
diacylglycerol kinase, eta
chr24_-_25787501 0.62 ENSDART00000015628
klhl24b
kelch-like family member 24b
chr13_-_33170733 0.60 ENSDART00000057382
fbln5
fibulin 5
chr3_+_13242690 0.60 ENSDART00000157097
sun1
Sad1 and UNC84 domain containing 1
chr7_-_56606752 0.60 ENSDART00000138714
sult5a1
sulfotransferase family 5A, member 1
chr17_+_25871304 0.59 ENSDART00000185143
wapla
WAPL cohesin release factor a
chr7_+_9981757 0.59 ENSDART00000113429
ENSDART00000173233
adamts17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr23_-_452365 0.59 ENSDART00000146776
tspan2b
tetraspanin 2b
chr13_-_13751017 0.58 ENSDART00000180182
ky
kyphoscoliosis peptidase
chr3_+_37824268 0.57 ENSDART00000137038
asic2
acid-sensing (proton-gated) ion channel 2
chr18_-_7948188 0.53 ENSDART00000091805
shank3a
SH3 and multiple ankyrin repeat domains 3a
chr16_-_20707742 0.53 ENSDART00000103630
creb5b
cAMP responsive element binding protein 5b
chr9_-_12424231 0.50 ENSDART00000188952
zgc:162707
zgc:162707
chr7_+_56889879 0.49 ENSDART00000039810
myo9aa
myosin IXAa
chr6_-_29195642 0.49 ENSDART00000078625
dpt
dermatopontin
chr4_-_49827366 0.49 ENSDART00000183761
si:dkey-156k2.3
si:dkey-156k2.3
chr19_-_35596207 0.49 ENSDART00000136811
col8a2
collagen, type VIII, alpha 2
chr3_+_56366395 0.47 ENSDART00000154367
cacng5b
calcium channel, voltage-dependent, gamma subunit 5b
chr15_-_8517376 0.47 ENSDART00000186289
npas1
neuronal PAS domain protein 1
chr9_-_12424791 0.45 ENSDART00000135447
ENSDART00000088199
zgc:162707
zgc:162707
chr19_+_4443285 0.44 ENSDART00000162683
trappc9
trafficking protein particle complex 9
chr16_+_45425181 0.43 ENSDART00000168591
phf1
PHD finger protein 1
chr6_-_36182115 0.43 ENSDART00000154639
brinp3a.2
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 2
chr3_-_8388344 0.42 ENSDART00000146856
rbfox3b
RNA binding fox-1 homolog 3b
chr15_-_16070731 0.41 ENSDART00000122099
dynll2a
dynein, light chain, LC8-type 2a
chr16_+_8716800 0.41 ENSDART00000124693
ENSDART00000181961
cabz01093075.1
cabz01093075.1
chr3_+_4047789 0.40 ENSDART00000148498
si:dkeyp-52c3.5
si:dkeyp-52c3.5
chr2_+_26060528 0.40 ENSDART00000058111
grin3ba
glutamate receptor, ionotropic, N-methyl-D-aspartate 3Ba
chr7_-_31794476 0.39 ENSDART00000142385
nap1l4b
nucleosome assembly protein 1-like 4b
chr5_-_31904562 0.38 ENSDART00000140640
coro1cb
coronin, actin binding protein, 1Cb
chr24_-_37877743 0.38 ENSDART00000105658
tmem204
transmembrane protein 204
chr22_-_5933844 0.38 ENSDART00000163370
ENSDART00000189331
si:rp71-36a1.2
si:rp71-36a1.2
chr17_-_34952562 0.37 ENSDART00000021128
kidins220a
kinase D-interacting substrate 220a
chr3_+_17537352 0.37 ENSDART00000104549
hcrt
hypocretin (orexin) neuropeptide precursor
chr5_-_21888368 0.35 ENSDART00000020725
smarca1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr4_-_1015896 0.33 ENSDART00000170292
FAM180A
family with sequence similarity 180 member A
chr5_+_33067283 0.33 ENSDART00000085821
npffr2b
neuropeptide FF receptor 2b
chr8_-_29706882 0.32 ENSDART00000045909
prf1.5
perforin 1.5
chr2_+_31671545 0.31 ENSDART00000145446
ackr4a
atypical chemokine receptor 4a
chr6_+_9398074 0.31 ENSDART00000151772
kalrnb
kalirin RhoGEF kinase b
chr20_-_13673566 0.31 ENSDART00000181641
TAGAP
si:ch211-122h15.4
chr14_-_9350364 0.30 ENSDART00000164451
fam46d
family with sequence similarity 46, member D
chr9_-_44983666 0.30 ENSDART00000149704
itgb2
integrin, beta 2
chr2_+_6303639 0.30 ENSDART00000132859
otol1a
otolin 1a
chr6_+_51824596 0.29 ENSDART00000149003
rspo4
R-spondin 4
chr19_-_20093341 0.29 ENSDART00000129917
mpp6b
membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)
chr22_-_26558166 0.26 ENSDART00000111125
glis2a
GLIS family zinc finger 2a
chr17_+_42274240 0.26 ENSDART00000134377
pax1a
paired box 1a
chr4_+_9609905 0.26 ENSDART00000142284
ENSDART00000150687
meig1
meiosis/spermiogenesis associated 1
chr2_+_21485492 0.25 ENSDART00000185303
inhbab
inhibin, beta Ab
chr19_+_24882845 0.25 ENSDART00000010580
si:ch211-195b13.1
si:ch211-195b13.1
chr7_-_52153105 0.24 ENSDART00000174378
CT737190.1

chr10_+_21867307 0.24 ENSDART00000126629
cbln17
cerebellin 17
chr24_-_26622423 0.23 ENSDART00000182044
tnikb
TRAF2 and NCK interacting kinase b
chr2_+_36646451 0.23 ENSDART00000039174
klhl6
kelch-like family member 6
chr12_+_13652747 0.23 ENSDART00000066359
oplah
5-oxoprolinase, ATP-hydrolysing
chr24_-_37877978 0.23 ENSDART00000128574
tmem204
transmembrane protein 204
chr11_+_10548171 0.22 ENSDART00000191497
b3gnt5a
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr5_-_19861766 0.21 ENSDART00000088904
gltpa
glycolipid transfer protein a
chr1_+_49878000 0.20 ENSDART00000047876
lef1
lymphoid enhancer-binding factor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb18+zbtb42

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0097052 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.6 1.9 GO:0072579 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.6 1.7 GO:0015942 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.5 3.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.4 4.0 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.4 2.8 GO:0043092 amino acid import(GO:0043090) L-amino acid import(GO:0043092)
0.3 4.3 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.3 0.8 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 2.4 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.2 2.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 1.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 0.6 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.2 0.7 GO:0090161 Golgi ribbon formation(GO:0090161)
0.2 3.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.2 0.3 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.2 1.3 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.2 1.1 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 1.1 GO:0038026 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.1 2.2 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 1.7 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 0.7 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.1 0.5 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.1 2.7 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.8 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 0.4 GO:0042755 eating behavior(GO:0042755)
0.1 1.9 GO:0015671 oxygen transport(GO:0015671)
0.1 0.6 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.7 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 1.5 GO:0006775 fat-soluble vitamin metabolic process(GO:0006775)
0.1 1.4 GO:0031060 regulation of histone methylation(GO:0031060)
0.1 4.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.4 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.1 0.7 GO:1901998 toxin transport(GO:1901998)
0.1 1.1 GO:0032264 IMP salvage(GO:0032264)
0.1 1.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.5 GO:2000463 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 4.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 1.2 GO:0048899 anterior lateral line development(GO:0048899)
0.1 1.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 1.3 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 1.5 GO:0060348 bone development(GO:0060348)
0.1 1.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 1.0 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.1 1.0 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 1.5 GO:0019835 cytolysis(GO:0019835)
0.0 0.3 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.7 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.1 GO:0002369 T cell cytokine production(GO:0002369)
0.0 1.1 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.5 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 1.5 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.2 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.0 1.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 1.0 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.5 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968) neurotransmitter receptor internalization(GO:0099590)
0.0 1.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.9 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.8 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 1.1 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 7.2 GO:0006887 exocytosis(GO:0006887)
0.0 1.2 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.0 0.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 1.1 GO:0030901 midbrain development(GO:0030901)
0.0 1.6 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 1.1 GO:0030282 bone mineralization(GO:0030282)
0.0 1.7 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.6 GO:0051923 sulfation(GO:0051923)
0.0 4.0 GO:0051216 cartilage development(GO:0051216)
0.0 0.6 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.7 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.5 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 2.7 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.9 GO:0030667 secretory granule membrane(GO:0030667)
0.3 2.4 GO:0000798 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.2 1.6 GO:0031045 dense core granule(GO:0031045)
0.2 2.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 2.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 4.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.2 1.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 0.8 GO:0005883 neurofilament(GO:0005883)
0.1 4.3 GO:0005844 polysome(GO:0005844)
0.1 2.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 1.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 4.3 GO:0005861 troponin complex(GO:0005861)
0.1 4.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.7 GO:0070938 contractile ring(GO:0070938)
0.1 0.4 GO:0016589 NURF complex(GO:0016589)
0.1 1.0 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 1.4 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.3 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 4.3 GO:0099572 postsynaptic specialization(GO:0099572)
0.0 0.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.1 GO:0016342 catenin complex(GO:0016342)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.7 GO:0016605 PML body(GO:0016605)
0.0 1.5 GO:0031201 SNARE complex(GO:0031201)
0.0 1.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0043186 P granule(GO:0043186)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 1.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.5 GO:0030426 growth cone(GO:0030426)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0042166 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
0.7 3.7 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.6 1.9 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.5 1.5 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.4 1.5 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.3 1.7 GO:0016841 ammonia-lyase activity(GO:0016841)
0.3 0.9 GO:0097643 amylin receptor activity(GO:0097643)
0.3 1.9 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.3 1.9 GO:0098809 nitrite reductase activity(GO:0098809)
0.3 3.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 1.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 1.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.2 0.7 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.2 1.9 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 1.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 2.8 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.2 1.0 GO:0031852 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 0.6 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.2 1.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 3.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.8 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 3.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 2.9 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 2.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.4 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.7 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.5 GO:0035255 GKAP/Homer scaffold activity(GO:0030160) ionotropic glutamate receptor binding(GO:0035255)
0.1 0.2 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.7 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 1.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 4.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0031628 opioid receptor binding(GO:0031628)
0.0 1.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.8 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 1.1 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.7 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 1.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.3 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 1.2 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 2.8 GO:0020037 heme binding(GO:0020037)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.1 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.4 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.0 PID CONE PATHWAY Visual signal transduction: Cones
0.1 1.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 1.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 3.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.9 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 5.7 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.2 2.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 3.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.9 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 1.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation