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PRJEB1986: zebrafish developmental stages transcriptome

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Results for znf711

Z-value: 2.64

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Transcription factors associated with znf711

Gene Symbol Gene ID Gene Info
ENSDARG00000071868 Danio rerio zinc finger protein 711 (znf711), transcript variant 1, mRNA.
ENSDARG00000111963 zinc finger protein 711

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
znf711dr11_v1_chr14_-_12020653_120206530.532.1e-02Click!

Activity profile of znf711 motif

Sorted Z-values of znf711 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_23768898 11.52 ENSDART00000110682
homeobox B1a
chr7_-_48667056 5.79 ENSDART00000006378
cyclin-dependent kinase inhibitor 1Ca
chr13_+_45967179 5.15 ENSDART00000074499
oligodendrocyte transcription factor 4
chr24_+_17005647 4.94 ENSDART00000149149
zinc finger protein, X-linked
chr23_-_9859989 4.44 ENSDART00000005015
protein kinase C binding protein 1, like
chr23_-_3758637 4.35 ENSDART00000131536
ENSDART00000139408
ENSDART00000137826
high mobility group AT-hook 1a
chr22_-_10541372 4.31 ENSDART00000179708
si:dkey-42i9.4
chr1_-_33557915 4.24 ENSDART00000075632
cAMP responsive element binding protein 1a
chr3_+_23743139 4.03 ENSDART00000187409
homeobox B3a
chr16_+_25163443 3.97 ENSDART00000105514
zinc finger protein 576, tandem duplicate 2
chr3_+_17653784 3.95 ENSDART00000159984
ENSDART00000157682
ENSDART00000187937
K(lysine) acetyltransferase 2A
chr20_-_24183333 3.92 ENSDART00000025862
ENSDART00000153075
mitogen-activated protein kinase kinase kinase 7
chr5_-_18007077 3.91 ENSDART00000129878
zinc finger, DHHC-type containing 8b
chr25_-_26736088 3.88 ENSDART00000067114
F-box and leucine-rich repeat protein 22
chr22_+_18349794 3.62 ENSDART00000186580
GATA zinc finger domain containing 2Ab
chr3_+_54581987 3.60 ENSDART00000018071
eukaryotic translation initiation factor 3, subunit G
chr11_-_39105253 3.52 ENSDART00000102827
prolyl 3-hydroxylase 1
chr23_-_10175898 3.48 ENSDART00000146185
keratin 5
chr3_+_23742868 3.43 ENSDART00000153512
homeobox B3a
chr13_+_29778610 3.42 ENSDART00000132004
paired box 2a
chr22_-_10541712 3.29 ENSDART00000013933
si:dkey-42i9.4
chr7_+_24393678 3.27 ENSDART00000188690
HAUS augmin-like complex, subunit 3
chr4_-_5831522 3.22 ENSDART00000008898
forkhead box M1
chr2_-_38080075 3.19 ENSDART00000056544
TOX high mobility group box family member 4 a
chr3_+_34149337 3.19 ENSDART00000006091
coactivator-associated arginine methyltransferase 1
chr7_-_6279138 3.18 ENSDART00000173299
si:ch211-220f21.2
chr14_+_31493306 3.12 ENSDART00000138341
PHD finger protein 6
chr2_+_3044992 3.11 ENSDART00000020463
zgc:63882
chr2_+_16798923 3.10 ENSDART00000181603
ENSDART00000179816
ENSDART00000087107
ENSDART00000187009
eukaryotic translation initiation factor 4 gamma, 1a
chr14_+_41887070 3.08 ENSDART00000173264
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr25_+_34845115 3.05 ENSDART00000061996
transmembrane protein 231
chr16_-_25680666 3.03 ENSDART00000132693
ENSDART00000140539
ENSDART00000015302
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr3_+_43086548 3.02 ENSDART00000163579
si:dkey-43p13.5
chr3_+_23752150 3.02 ENSDART00000146636
homeobox B2a
chr20_+_1329509 3.00 ENSDART00000017791
ENSDART00000136669
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr11_-_18107447 2.99 ENSDART00000187376
glutamine-rich 1
chr9_+_21306902 2.99 ENSDART00000138554
ENSDART00000004108
exportin 4
chr4_+_6032640 2.99 ENSDART00000157487
transcription factor EC
chr22_-_22242884 2.98 ENSDART00000020937
HDGF like 2
chr23_+_28378543 2.97 ENSDART00000145327
zgc:153867
chr17_-_44247707 2.96 ENSDART00000126097
orthodenticle homeobox 2b
chr11_-_22599584 2.95 ENSDART00000014062
myogenin
chr4_-_5831036 2.94 ENSDART00000166232
forkhead box M1
chr1_-_54972170 2.93 ENSDART00000150548
ENSDART00000038330
KH-type splicing regulatory protein
chr1_-_28885919 2.92 ENSDART00000152182
protein O-glucosyltransferase 1
chr19_+_48019070 2.88 ENSDART00000158269
si:ch1073-205c8.3
chr8_-_1051438 2.85 ENSDART00000067093
ENSDART00000170737
SET and MYND domain containing 1b
chr16_+_31921812 2.84 ENSDART00000176928
ENSDART00000193733
ribosomal protein S9
chr5_-_23464970 2.84 ENSDART00000141028
si:dkeyp-20g2.1
chr23_+_35650771 2.81 ENSDART00000005158
cyclin T1
chr2_-_37134169 2.80 ENSDART00000146123
ENSDART00000146533
ENSDART00000040427
ELAV like RNA binding protein 1a
chr1_-_23370395 2.80 ENSDART00000143014
ENSDART00000126785
ENSDART00000159138
PDS5 cohesin associated factor A
chr3_-_5644028 2.80 ENSDART00000019957
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Ab
chr15_+_24549054 2.77 ENSDART00000155900
PHD finger protein 12b
chr3_+_18807524 2.76 ENSDART00000055757
transportin 2 (importin 3, karyopherin beta 2b)
chr17_-_42213285 2.76 ENSDART00000140549
NK2 homeobox 2a
chr14_+_31493119 2.76 ENSDART00000006463
PHD finger protein 6
chr20_-_24182689 2.74 ENSDART00000171184
mitogen-activated protein kinase kinase kinase 7
chr11_-_3860534 2.71 ENSDART00000082425
GATA binding protein 2a
chr11_-_18017918 2.70 ENSDART00000040171
glutamine-rich 1
chr16_+_25066880 2.70 ENSDART00000154084
im:7147486
chr18_-_21748808 2.61 ENSDART00000079253
protein serine kinase H1
chr1_+_52792439 2.61 ENSDART00000123972
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr6_+_28877306 2.60 ENSDART00000065137
ENSDART00000123189
ENSDART00000065135
ENSDART00000181512
ENSDART00000130799
tumor protein p63
chr10_-_35186310 2.59 ENSDART00000127805
POM121 transmembrane nucleoporin
chr10_-_27197044 2.56 ENSDART00000137928
autism susceptibility candidate 2a
chr20_+_29209615 2.54 ENSDART00000062350
katanin p80 subunit B-like 1
chr24_+_17140938 2.50 ENSDART00000149134
MLLT10, histone lysine methyltransferase DOT1L cofactor
chr20_-_9199721 2.49 ENSDART00000064140
YLP motif containing 1
chr4_+_9177997 2.48 ENSDART00000057254
ENSDART00000154614
nuclear transcription factor Y, beta a
chr25_-_17378881 2.46 ENSDART00000064586
cytochrome P450, family 2, subfamily X, polypeptide 7
chr11_-_127785 2.46 ENSDART00000162658
ADP ribosylation factor GTPase activating protein 1
chr13_+_21870269 2.43 ENSDART00000144612
zinc finger, SWIM-type containing 8
chr19_+_31585917 2.42 ENSDART00000132182
geminin, DNA replication inhibitor
chr16_+_28728347 2.42 ENSDART00000149240
si:dkey-24i24.3
chr9_-_32300611 2.40 ENSDART00000127938
heat shock 60 protein 1
chr1_-_19079957 2.40 ENSDART00000141795
paired-like homeobox 2ba
chr23_-_43718067 2.40 ENSDART00000015777
ATP-binding cassette, sub-family E (OABP), member 1
chr3_+_32410746 2.38 ENSDART00000025496
RAS related
chr15_-_4616816 2.37 ENSDART00000160191
ENSDART00000161721
ENSDART00000144949
eukaryotic translation initiation factor 4h
chr8_+_26372115 2.37 ENSDART00000053460
N-acetyltransferase 6
chr23_-_4704938 2.37 ENSDART00000067293
CCHC-type zinc finger, nucleic acid binding protein a
chr23_-_43486714 2.37 ENSDART00000169726
E2F transcription factor 1
chr4_-_2059233 2.36 ENSDART00000188177
ENSDART00000129521
ENSDART00000082289
cleavage and polyadenylation specific factor 6
chr13_+_51710725 2.34 ENSDART00000163741
PWWP domain containing 2B
chr1_-_54971968 2.31 ENSDART00000140016
KH-type splicing regulatory protein
chr8_-_31416403 2.29 ENSDART00000098912
zinc finger protein 131
chr25_+_26901149 2.28 ENSDART00000153839
zinc finger protein 800a
chr16_+_31922065 2.27 ENSDART00000131661
ENSDART00000144194
ENSDART00000145510
ribosomal protein S9
chr22_-_10752471 2.27 ENSDART00000081191
SAS-6 centriolar assembly protein
chr1_-_45580787 2.25 ENSDART00000135089
activating transcription factor 7 interacting protein
chr1_-_55183088 2.25 ENSDART00000100619
zgc:158803
chr5_+_30520249 2.25 ENSDART00000013431
hydroxymethylbilane synthase a
chr3_+_22984098 2.23 ENSDART00000043190
LSM12 homolog a
chr20_-_18535502 2.23 ENSDART00000049437
CDC42 binding protein kinase beta (DMPK-like)
chr18_-_46354269 2.23 ENSDART00000010813
forkhead box A3
chr23_-_9864166 2.21 ENSDART00000124510
ENSDART00000187934
protein kinase C binding protein 1, like
chr24_+_21514283 2.20 ENSDART00000007066
cyclin-dependent kinase 8
chr25_-_8513255 2.20 ENSDART00000150129
polymerase (DNA directed), gamma
chr1_+_59538755 2.20 ENSDART00000166354
Sp6 transcription factor
chr7_+_72012397 2.19 ENSDART00000011303
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2
chr25_-_11026907 2.19 ENSDART00000156846
mesoderm posterior bb
chr20_+_34770197 2.18 ENSDART00000018304
minichromosome maintenance complex component 3
chr16_-_46578523 2.16 ENSDART00000131061
si:dkey-152b24.6
chr17_-_42213822 2.15 ENSDART00000187904
ENSDART00000180029
NK2 homeobox 2a
chr13_-_37600600 2.15 ENSDART00000003888
small nuclear RNA activating complex, polypeptide 1b
chr23_+_28378006 2.13 ENSDART00000188915
zgc:153867
chr18_-_15610856 2.12 ENSDART00000099849
aryl hydrocarbon receptor nuclear translocator-like 2
chr18_+_44631789 2.12 ENSDART00000144271
BRD4 interacting chromatin remodeling complex associated protein
chr19_+_48018802 2.11 ENSDART00000161339
ENSDART00000166978
si:ch1073-205c8.3
chr18_-_24988645 2.07 ENSDART00000136434
ENSDART00000085735
chromodomain helicase DNA binding protein 2
chr24_+_4434117 2.06 ENSDART00000184349
gap junction protein delta 4
chr17_-_10838434 2.04 ENSDART00000064597
lectin, galactoside binding soluble 3b
chr21_-_3007412 2.04 ENSDART00000190839
zgc:86839
chr5_+_45000597 2.02 ENSDART00000051146
doublesex and mab-3 related transcription factor 3a
chr13_-_44738574 2.01 ENSDART00000074761
zinc finger, AN1-type domain 3
chr25_-_3590923 1.99 ENSDART00000164149
si:ch211-272n13.3
chr23_-_29858087 1.97 ENSDART00000109506
transmembrane protein 201
chr7_+_22747915 1.97 ENSDART00000173609
fragile X mental retardation, autosomal homolog 2
chr1_-_57172294 1.95 ENSDART00000063774
Rac family small GTPase 1, like
chr25_+_17313568 1.95 ENSDART00000125459
CCR4-NOT transcription complex, subunit 1
chr23_-_16737161 1.94 ENSDART00000132573
si:ch211-224l10.4
chr3_+_50201240 1.91 ENSDART00000156347
epsin 3a
chr9_-_33107237 1.91 ENSDART00000013918
calsequestrin 2
chr7_+_20260172 1.91 ENSDART00000012450
dishevelled segment polarity protein 2
chr20_+_26939742 1.90 ENSDART00000138369
ENSDART00000062061
ENSDART00000152992
cell division cycle associated 4
chr13_+_11829072 1.89 ENSDART00000079356
ENSDART00000170160
suppressor of fused homolog (Drosophila)
chr16_+_20055878 1.89 ENSDART00000146436
ankyrin repeat domain 28b
chr4_-_9191220 1.86 ENSDART00000156919
host cell factor C2
chr6_-_39893501 1.86 ENSDART00000141611
ENSDART00000135631
ENSDART00000077662
ENSDART00000130613
myosin, light chain 6, alkali, smooth muscle and non-muscle
chr21_-_11970199 1.85 ENSDART00000114524
NOP56 ribonucleoprotein homolog
chr7_+_49654588 1.84 ENSDART00000025451
ENSDART00000141934
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr17_+_42027969 1.82 ENSDART00000147563
kizuna centrosomal protein
chr6_-_138392 1.82 ENSDART00000148974
kelch-like ECH-associated protein 1b
chr13_-_36535128 1.81 ENSDART00000043312
serine/arginine-rich splicing factor 5a
chr8_+_12951155 1.80 ENSDART00000081601
choline/ethanolamine phosphotransferase 1a
chr24_-_7957581 1.80 ENSDART00000145815
thioredoxin domain containing 5
chr7_-_66126628 1.80 ENSDART00000184492
BTB (POZ) domain containing 10b
chr17_+_4325693 1.80 ENSDART00000154264
minichromosome maintenance 8 homologous recombination repair factor
chr16_-_39477746 1.79 ENSDART00000102525
STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
chr5_-_72390259 1.79 ENSDART00000172302
WW domain binding protein 1
chr16_-_31621719 1.78 ENSDART00000176939
PHD finger protein 20 like 1
chr11_+_6010177 1.77 ENSDART00000170047
ENSDART00000022526
ENSDART00000161001
ENSDART00000188999
GTP binding protein 3, mitochondrial
chr16_-_26676685 1.76 ENSDART00000103431
epithelial splicing regulatory protein 1
chr11_-_55224 1.76 ENSDART00000159169
collagen, type II, alpha 1b
chr18_-_17147803 1.76 ENSDART00000187986
ENSDART00000169080
zinc finger CCCH-type containing 18
chr7_-_18508815 1.75 ENSDART00000173539
regulator of G protein signaling 12a
chr5_-_30516646 1.74 ENSDART00000014666
archain 1a
chr7_+_40081630 1.74 ENSDART00000173559
zgc:112356
chr2_-_42173834 1.74 ENSDART00000098357
ENSDART00000144707
solute carrier family 39 (zinc transporter), member 6
chr3_-_40529782 1.72 ENSDART00000055194
ENSDART00000141737
actin, beta 2
chr9_-_29036263 1.72 ENSDART00000160393
transmembrane protein 177
chr15_-_35960250 1.71 ENSDART00000186765
collagen, type IV, alpha 4
chr6_+_32326074 1.71 ENSDART00000042134
ENSDART00000181177
dedicator of cytokinesis 7
chr19_+_31585341 1.70 ENSDART00000052185
geminin, DNA replication inhibitor
chr1_-_35924495 1.70 ENSDART00000184424
SMAD family member 1
chr16_+_16529748 1.69 ENSDART00000029579
coiled-coil domain containing 12
chr13_+_32148338 1.68 ENSDART00000188591
odd-skipped related transciption factor 1
chr16_+_20056030 1.67 ENSDART00000027020
ankyrin repeat domain 28b
chr13_-_23007813 1.67 ENSDART00000057638
hexokinase 1
chr5_-_1963498 1.67 ENSDART00000073462
ribosomal protein, large, P0
chr25_-_21280584 1.67 ENSDART00000143644
transmembrane protein 60
chr1_+_8508753 1.66 ENSDART00000091683
alkB homolog 5, RNA demethylase
chr7_-_59564011 1.62 ENSDART00000186053
zgc:112271
chr25_+_30460378 1.62 ENSDART00000016310
BTG3 associated nuclear protein
chr2_-_2813259 1.62 ENSDART00000032540
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
chr18_-_50839033 1.61 ENSDART00000169773
damage-specific DNA binding protein 1
chr4_-_35899188 1.61 ENSDART00000167093
zgc:174653
chr20_+_29209767 1.61 ENSDART00000141252
katanin p80 subunit B-like 1
chr13_+_24280380 1.61 ENSDART00000184115
actin, alpha 1b, skeletal muscle
chr13_-_36534380 1.58 ENSDART00000177857
ENSDART00000181046
ENSDART00000187243
serine/arginine-rich splicing factor 5a
chr7_+_41146560 1.56 ENSDART00000143285
ENSDART00000173852
ENSDART00000174003
ENSDART00000038487
ENSDART00000173463
ENSDART00000166448
ENSDART00000052274
poly-U binding splicing factor b
chr18_-_17147600 1.56 ENSDART00000141873
zinc finger CCCH-type containing 18
chr7_-_52531252 1.55 ENSDART00000174369
transcription factor 12
chr14_+_21686207 1.55 ENSDART00000034438
RAN, member RAS oncogene family
chr17_-_44249538 1.55 ENSDART00000008816
orthodenticle homeobox 2b
chr1_+_21731382 1.55 ENSDART00000054395
paired box 5
chr3_+_27607268 1.53 ENSDART00000024453
ubiquitin specific peptidase 7 (herpes virus-associated)
chr23_+_43718115 1.52 ENSDART00000149266
ENSDART00000149503
anaphase promoting complex subunit 10
chr11_-_5953636 1.52 ENSDART00000140960
ENSDART00000123601
DET1 and DDB1 associated 1
chr7_-_41915312 1.51 ENSDART00000159869
DnaJ (Hsp40) homolog, subfamily A, member 2
chr3_-_15496295 1.49 ENSDART00000144369
SAGA complex associated factor 29
chr24_-_26945390 1.49 ENSDART00000123354
male-specific lethal 2 homolog b (Drosophila)
chr9_+_8898024 1.49 ENSDART00000134954
ENSDART00000143671
ENSDART00000147098
ENSDART00000179969
ENSDART00000111214
ENSDART00000140232
ENSDART00000139687
ENSDART00000132443
ENSDART00000130208
NAD(P)HX dehydratase
chr9_-_25181137 1.48 ENSDART00000192624
esterase D/formylglutathione hydrolase
chr5_-_12219572 1.47 ENSDART00000167834
nitric oxide synthase 1 (neuronal)
chr23_+_24926407 1.47 ENSDART00000137486
kelch-like family member 21
chr3_+_32631372 1.47 ENSDART00000129339
serine/arginine repetitive matrix 2
chr5_-_33607062 1.46 ENSDART00000048350
si:dkey-34e4.1
chr24_+_36239617 1.44 ENSDART00000062745
RIO kinase 3 (yeast)
chr2_-_3044947 1.43 ENSDART00000192642
guanylate kinase 1a
chr13_+_11876437 1.42 ENSDART00000179753
tripartite motif containing 8a
chr25_+_5249513 1.40 ENSDART00000126814

chr9_-_25366541 1.40 ENSDART00000021672
enhancer of polycomb homolog 2 (Drosophila)
chr4_+_18489207 1.39 ENSDART00000135276
si:dkey-202b22.5
chr17_+_30751462 1.38 ENSDART00000154184
lipid droplet associated hydrolase
chr22_+_10752787 1.38 ENSDART00000186542
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr3_-_15496551 1.37 ENSDART00000124063
ENSDART00000007726
SAGA complex associated factor 29
chr6_-_42369186 1.36 ENSDART00000039868
ubiquitin specific peptidase 4 (proto-oncogene)
chr22_-_4769140 1.36 ENSDART00000165235
calreticulin 3a

Network of associatons between targets according to the STRING database.

First level regulatory network of znf711

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 11.5 GO:0021661 rhombomere 4 development(GO:0021570) rhombomere 4 morphogenesis(GO:0021661)
1.6 4.9 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
1.3 5.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.9 2.7 GO:0061614 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.9 5.2 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.8 5.8 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.8 3.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.8 2.4 GO:0046833 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833) messenger ribonucleoprotein complex assembly(GO:1990120)
0.7 2.2 GO:0048785 hatching gland development(GO:0048785)
0.6 2.4 GO:0032755 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
0.6 2.9 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.6 1.7 GO:0048389 intermediate mesoderm development(GO:0048389)
0.6 5.0 GO:0060114 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.5 2.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.5 5.8 GO:0006611 protein export from nucleus(GO:0006611)
0.5 2.5 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.5 1.5 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.5 1.9 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.5 1.9 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.5 1.9 GO:1900181 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.4 6.2 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.4 1.7 GO:0051645 Golgi localization(GO:0051645)
0.4 1.7 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.4 2.0 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.4 3.9 GO:0086003 cardiac muscle cell contraction(GO:0086003)
0.4 1.5 GO:0061015 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.4 2.2 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.4 3.0 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.4 2.2 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.4 1.1 GO:0044246 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.3 2.4 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.3 3.9 GO:1903010 regulation of bone development(GO:1903010)
0.3 2.6 GO:0048730 epidermis morphogenesis(GO:0048730)
0.3 2.3 GO:0040016 embryonic cleavage(GO:0040016)
0.3 1.3 GO:0070084 protein initiator methionine removal(GO:0070084)
0.3 1.0 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.3 2.2 GO:1902292 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.3 0.9 GO:0034672 anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.3 0.9 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.3 6.9 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.3 4.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.3 1.9 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.3 3.6 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.3 0.8 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 0.7 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.2 0.7 GO:0021698 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698)
0.2 2.2 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.2 2.7 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.2 2.2 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.2 0.7 GO:0072020 proximal straight tubule development(GO:0072020)
0.2 1.5 GO:0046294 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.2 1.0 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.2 0.2 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.2 1.0 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.2 2.9 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.2 2.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 1.7 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.2 2.5 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.2 2.0 GO:0046661 male sex differentiation(GO:0046661)
0.2 1.8 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.2 0.5 GO:0002188 translation reinitiation(GO:0002188)
0.2 2.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 10.0 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.2 2.9 GO:0033750 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.2 3.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.2 2.9 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.2 1.7 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.6 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.1 1.5 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 2.6 GO:0016584 nucleosome positioning(GO:0016584)
0.1 2.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.1 1.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 3.6 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 0.5 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 1.7 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.1 1.9 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.5 GO:0046551 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.1 1.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 3.0 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 1.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 2.8 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.1 1.4 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.1 0.7 GO:0006574 valine catabolic process(GO:0006574)
0.1 1.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 2.8 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.1 8.1 GO:0034504 protein localization to nucleus(GO:0034504)
0.1 4.1 GO:0044259 collagen metabolic process(GO:0032963) multicellular organismal macromolecule metabolic process(GO:0044259)
0.1 3.9 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 1.5 GO:0034629 cellular protein complex localization(GO:0034629)
0.1 2.6 GO:0021884 forebrain neuron development(GO:0021884)
0.1 1.3 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 0.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 3.5 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 0.8 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 0.7 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 5.4 GO:0048484 enteric nervous system development(GO:0048484)
0.1 2.8 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.1 1.8 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 1.2 GO:1902284 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.1 1.9 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.3 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.1 0.2 GO:0002369 T cell cytokine production(GO:0002369)
0.1 4.2 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 1.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 0.5 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 0.5 GO:0030728 ovulation(GO:0030728)
0.1 1.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 7.6 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.1 2.3 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 2.1 GO:0009648 photoperiodism(GO:0009648)
0.1 2.8 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.1 0.9 GO:0060030 dorsal convergence(GO:0060030)
0.1 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 1.4 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.1 1.6 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 0.7 GO:0045738 negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
0.1 1.8 GO:0032392 DNA geometric change(GO:0032392) DNA duplex unwinding(GO:0032508)
0.1 1.3 GO:0006491 N-glycan processing(GO:0006491)
0.1 3.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 8.9 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 0.2 GO:0007141 male meiosis I(GO:0007141)
0.1 2.7 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 2.8 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1 3.3 GO:0051225 spindle assembly(GO:0051225) definitive hemopoiesis(GO:0060216)
0.1 1.5 GO:0031647 regulation of protein stability(GO:0031647)
0.1 0.4 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.6 GO:0010634 positive regulation of epithelial cell migration(GO:0010634)
0.0 1.8 GO:0007051 spindle organization(GO:0007051)
0.0 1.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.8 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 1.0 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 1.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 1.3 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.7 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 1.4 GO:0019915 lipid storage(GO:0019915)
0.0 0.4 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 1.8 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 3.1 GO:0032880 regulation of protein localization(GO:0032880)
0.0 2.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.2 GO:1902547 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.0 1.4 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.2 GO:0070073 regulation of melanocyte differentiation(GO:0045634) clustering of voltage-gated calcium channels(GO:0070073)
0.0 1.8 GO:0016573 histone acetylation(GO:0016573)
0.0 0.7 GO:0070972 protein localization to endoplasmic reticulum(GO:0070972)
0.0 1.2 GO:0035194 posttranscriptional gene silencing(GO:0016441) posttranscriptional gene silencing by RNA(GO:0035194)
0.0 1.4 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.6 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 1.6 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 2.6 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.0 2.0 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 2.4 GO:1902667 regulation of axon guidance(GO:1902667)
0.0 1.7 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.4 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 2.0 GO:1904888 cranial skeletal system development(GO:1904888)
0.0 7.0 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 1.3 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.4 GO:0006612 protein targeting to membrane(GO:0006612)
0.0 5.3 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 1.0 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.2 GO:1904861 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) excitatory synapse assembly(GO:1904861) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.4 GO:0045786 negative regulation of cell cycle(GO:0045786)
0.0 1.0 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 1.8 GO:0016579 protein deubiquitination(GO:0016579)
0.0 1.5 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.4 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 1.1 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 1.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 2.8 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 1.6 GO:0010564 regulation of cell cycle process(GO:0010564)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.9 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.6 GO:0001755 neural crest cell migration(GO:0001755)
0.0 34.4 GO:0006355 regulation of transcription, DNA-templated(GO:0006355)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.9 GO:0009615 response to virus(GO:0009615)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0042382 paraspeckles(GO:0042382)
0.8 2.3 GO:0098536 deuterosome(GO:0098536)
0.7 2.1 GO:0019185 snRNA-activating protein complex(GO:0019185)
0.6 2.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.5 1.9 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.5 1.9 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.5 1.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.4 1.8 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.4 2.6 GO:0016589 NURF complex(GO:0016589)
0.4 2.6 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.4 3.3 GO:0070652 HAUS complex(GO:0070652)
0.4 1.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.4 3.9 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.3 1.7 GO:0097433 dense body(GO:0097433)
0.3 3.7 GO:0045095 keratin filament(GO:0045095)
0.3 2.9 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.3 2.8 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.3 1.9 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.3 6.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.3 3.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.3 2.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.3 1.9 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.3 1.8 GO:0016234 inclusion body(GO:0016234)
0.3 2.0 GO:0001772 immunological synapse(GO:0001772)
0.2 0.9 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.2 2.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 1.6 GO:0005667 transcription factor complex(GO:0005667)
0.2 4.0 GO:0042555 MCM complex(GO:0042555)
0.2 1.0 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.2 3.1 GO:0036038 MKS complex(GO:0036038)
0.2 3.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 2.5 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.2 1.5 GO:0072487 MSL complex(GO:0072487)
0.2 2.6 GO:0005869 dynactin complex(GO:0005869)
0.2 2.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 7.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 1.9 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 2.2 GO:0071564 npBAF complex(GO:0071564)
0.1 1.1 GO:0032797 SMN complex(GO:0032797)
0.1 1.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 2.8 GO:0070822 Sin3-type complex(GO:0070822)
0.1 7.7 GO:0005643 nuclear pore(GO:0005643)
0.1 2.1 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 2.5 GO:0031430 M band(GO:0031430)
0.1 1.0 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.8 GO:0044545 NSL complex(GO:0044545)
0.1 1.7 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 0.8 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 1.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.4 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.1 2.0 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 1.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 2.1 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 2.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.4 GO:0005899 insulin receptor complex(GO:0005899)
0.1 1.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.7 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 2.0 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 3.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.0 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 1.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 8.9 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.1 1.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 1.9 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.2 GO:0060171 stereocilium membrane(GO:0060171)
0.0 1.2 GO:0043186 P granule(GO:0043186)
0.0 0.3 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 2.2 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0071797 LUBAC complex(GO:0071797)
0.0 2.8 GO:0005814 centriole(GO:0005814)
0.0 1.3 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 1.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 8.0 GO:0000785 chromatin(GO:0000785)
0.0 8.4 GO:0005730 nucleolus(GO:0005730)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.0 1.7 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 2.0 GO:0000502 proteasome complex(GO:0000502)
0.0 2.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 141.8 GO:0005634 nucleus(GO:0005634)
0.0 1.9 GO:0030027 lamellipodium(GO:0030027)
0.0 3.8 GO:1990904 ribonucleoprotein complex(GO:1990904)
0.0 1.9 GO:0005819 spindle(GO:0005819)
0.0 2.0 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.8 GO:0001725 stress fiber(GO:0001725) actomyosin(GO:0042641) contractile actin filament bundle(GO:0097517)
0.0 0.5 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.7 2.9 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.7 5.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.6 3.2 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.5 1.6 GO:0052855 ATP-dependent NAD(P)H-hydrate dehydratase activity(GO:0047453) ADP-dependent NAD(P)H-hydrate dehydratase activity(GO:0052855)
0.5 5.2 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.5 2.0 GO:0005521 lamin binding(GO:0005521)
0.5 0.9 GO:1990715 mRNA CDS binding(GO:1990715)
0.4 2.9 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.4 1.7 GO:1990931 RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.4 2.0 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.4 4.8 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.4 2.2 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.4 1.8 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.4 2.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.3 1.7 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.3 1.9 GO:0030331 estrogen receptor binding(GO:0030331) retinoic acid receptor binding(GO:0042974)
0.3 6.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.3 3.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.3 6.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.3 1.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.3 1.7 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.3 1.7 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 3.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 1.0 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.2 4.2 GO:0035497 cAMP response element binding(GO:0035497)
0.2 0.9 GO:0070717 poly(A) binding(GO:0008143) poly-purine tract binding(GO:0070717)
0.2 1.5 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.2 3.0 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.2 1.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.2 2.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 0.7 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.2 3.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 0.7 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.2 0.7 GO:0033149 FFAT motif binding(GO:0033149)
0.2 4.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 2.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 0.8 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.2 3.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 2.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 1.8 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 1.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 5.7 GO:0019843 rRNA binding(GO:0019843)
0.1 1.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 0.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 4.6 GO:0019003 GDP binding(GO:0019003)
0.1 0.5 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 5.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 2.1 GO:0070122 isopeptidase activity(GO:0070122)
0.1 5.1 GO:0031491 nucleosome binding(GO:0031491)
0.1 1.9 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.8 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 3.9 GO:0045182 translation regulator activity(GO:0045182)
0.1 2.9 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.4 GO:0005009 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.1 1.7 GO:0070411 I-SMAD binding(GO:0070411)
0.1 4.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 3.9 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.5 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 1.0 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.7 GO:0035198 miRNA binding(GO:0035198)
0.1 2.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 2.4 GO:0051087 chaperone binding(GO:0051087)
0.1 1.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.0 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.4 GO:0036122 BMP binding(GO:0036122)
0.0 1.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.2 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.5 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 1.9 GO:0005109 frizzled binding(GO:0005109)
0.0 5.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 3.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 22.6 GO:0046983 protein dimerization activity(GO:0046983)
0.0 1.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 3.1 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 1.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 2.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 2.8 GO:0003724 RNA helicase activity(GO:0003724)
0.0 11.3 GO:0000989 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 5.6 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 66.9 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.8 GO:0043022 ribosome binding(GO:0043022)
0.0 0.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 7.2 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.5 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.6 GO:0051020 GTPase binding(GO:0051020)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 1.6 GO:0051536 iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.0 4.2 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.7 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 2.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.4 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.6 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 2.3 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 7.5 GO:0003723 RNA binding(GO:0003723)
0.0 4.3 GO:0003924 GTPase activity(GO:0003924)
0.0 0.4 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 1.3 GO:0019208 phosphatase regulator activity(GO:0019208)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.3 2.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3 5.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 3.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.2 4.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.2 6.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 6.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 3.6 PID RAS PATHWAY Regulation of Ras family activation
0.1 1.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 3.4 PID MYC PATHWAY C-MYC pathway
0.1 2.5 PID ARF 3PATHWAY Arf1 pathway
0.1 1.7 PID ALK2 PATHWAY ALK2 signaling events
0.1 2.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 5.2 PID CMYB PATHWAY C-MYB transcription factor network
0.1 3.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 1.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.6 PID P53 REGULATION PATHWAY p53 pathway
0.1 1.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.7 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 1.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 1.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 0.9 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 0.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 2.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.2 PID E2F PATHWAY E2F transcription factor network
0.0 1.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 2.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 9.7 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.4 6.5 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.4 3.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.4 1.8 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.4 3.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.3 5.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.3 14.7 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.2 2.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.2 5.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2 2.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 2.8 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.2 5.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 1.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 3.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 3.8 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.1 1.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 5.4 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 1.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 4.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 0.4 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 1.5 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 2.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.6 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 3.6 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.8 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.8 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.1 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking