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PRJEB1986: zebrafish developmental stages transcriptome

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Results for znf740b

Z-value: 0.93

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Transcription factors associated with znf740b

Gene Symbol Gene ID Gene Info
znf740b
ENSDARG00000061174 zinc finger protein 740b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
znf740bdr11_v1_chr23_-_36418708_36418708-0.734.3e-04Click!

Activity profile of znf740b motif

Sorted Z-values of znf740b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_6954984 8.90 ENSDART00000145610
si:ch211-255g12.6
si:ch211-255g12.6
chr25_-_18470695 3.76 ENSDART00000034377
cpa5
carboxypeptidase A5
chr21_+_25660613 3.32 ENSDART00000134017
si:dkey-17e16.15
si:dkey-17e16.15
chr6_+_38381957 2.80 ENSDART00000087300
gabrb3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr12_+_13244149 2.78 ENSDART00000186984
ENSDART00000105896
atp2a1l
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like
chr16_-_8280885 2.36 ENSDART00000129068
entpd3
ectonucleoside triphosphate diphosphohydrolase 3
chr12_-_4540564 2.32 ENSDART00000106566
CABZ01030107.1

chr3_-_1190132 2.24 ENSDART00000149709
smdt1a
single-pass membrane protein with aspartate-rich tail 1a
chr9_+_13714379 2.18 ENSDART00000017593
ENSDART00000145503
tmem237a
transmembrane protein 237a
chr11_-_24191928 2.15 ENSDART00000136827
sox12
SRY (sex determining region Y)-box 12
chr3_+_22327738 2.09 ENSDART00000055675
gh1
growth hormone 1
chr2_+_7192966 1.98 ENSDART00000142735
si:ch211-13f8.1
si:ch211-13f8.1
chr25_+_37366698 1.97 ENSDART00000165400
ENSDART00000192589
slc1a2b
solute carrier family 1 (glial high affinity glutamate transporter), member 2b
chr17_-_12389259 1.85 ENSDART00000185724
snap25b
synaptosomal-associated protein, 25b
chr3_-_52614747 1.83 ENSDART00000154365
trim35-13
tripartite motif containing 35-13
chr23_+_6232895 1.80 ENSDART00000139795
syt2a
synaptotagmin IIa
chr25_+_13191391 1.80 ENSDART00000109937
si:ch211-147m6.2
si:ch211-147m6.2
chr21_+_1143141 1.75 ENSDART00000178294
CABZ01086139.1

chr14_+_22172047 1.67 ENSDART00000114750
ENSDART00000148259
gabrb2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr3_-_61162750 1.66 ENSDART00000055064
pvalb8
parvalbumin 8
chr3_+_50312422 1.65 ENSDART00000157689
gas7a
growth arrest-specific 7a
chr11_-_97817 1.65 ENSDART00000092903
elmo2
engulfment and cell motility 2
chr20_-_25542183 1.60 ENSDART00000024350
cyp2ad2
cytochrome P450, family 2, subfamily AD, polypeptide 2
chr15_-_28618502 1.54 ENSDART00000086902
slc6a4a
solute carrier family 6 (neurotransmitter transporter), member 4a
chr7_-_27686021 1.53 ENSDART00000079112
ENSDART00000100989
calca
calcitonin/calcitonin-related polypeptide, alpha
chr8_-_22739757 1.49 ENSDART00000182167
ENSDART00000171891
iqsec2a
IQ motif and Sec7 domain 2a
chr19_+_48117995 1.42 ENSDART00000170865
nme2b.1
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1
chr21_-_37889727 1.39 ENSDART00000163612
ENSDART00000180958
gabrb4
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr19_-_6873107 1.35 ENSDART00000124440
CABZ01029822.1

chr24_-_32582378 1.34 ENSDART00000066590
rdh12l
retinol dehydrogenase 12, like
chr9_+_54290896 1.32 ENSDART00000149175
pou4f3
POU class 4 homeobox 3
chr22_+_35068046 1.31 ENSDART00000161660
ENSDART00000169573
si:ch73-173h19.3
si:ch73-173h19.3
chr15_-_5815006 1.31 ENSDART00000102459
rbp2a
retinol binding protein 2a, cellular
chr5_+_32162684 1.29 ENSDART00000134472
taok3b
TAO kinase 3b
chr10_-_43540196 1.21 ENSDART00000170891
si:ch73-215f7.1
si:ch73-215f7.1
chr16_-_27749172 1.18 ENSDART00000145198
steap4
STEAP family member 4
chr20_-_25518488 1.17 ENSDART00000186993
cyp2n13
cytochrome P450, family 2, subfamily N, polypeptide 13
chr20_+_20672163 1.17 ENSDART00000027758
rtn1b
reticulon 1b
chr22_+_24157807 1.16 ENSDART00000159165
b3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr12_+_5530247 1.15 ENSDART00000114637
ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr1_+_31112436 1.15 ENSDART00000075340
eef1a1b
eukaryotic translation elongation factor 1 alpha 1b
chr25_+_13191615 1.08 ENSDART00000168849
si:ch211-147m6.2
si:ch211-147m6.2
chr13_+_28702104 1.06 ENSDART00000135481
si:ch211-67n3.9
si:ch211-67n3.9
chr10_-_35542071 1.02 ENSDART00000162139
si:ch211-244c8.4
si:ch211-244c8.4
chr3_+_13440900 0.99 ENSDART00000143715
GNG14
si:dkey-117i10.1
chr11_+_38280454 0.97 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr5_-_68022631 0.96 ENSDART00000143199
wasf3a
WAS protein family, member 3a
chr1_+_51896147 0.95 ENSDART00000167139
nfixa
nuclear factor I/Xa
chr18_-_16181952 0.93 ENSDART00000157824
slc6a15
solute carrier family 6 (neutral amino acid transporter), member 15
chr14_+_33458294 0.93 ENSDART00000075278
atp1b4
ATPase Na+/K+ transporting subunit beta 4
chr19_+_13994563 0.92 ENSDART00000164696
tmem222b
transmembrane protein 222b
chr19_-_7358184 0.92 ENSDART00000092379
oxr1b
oxidation resistance 1b
chr18_+_21122818 0.91 ENSDART00000060015
ENSDART00000060184
chka
choline kinase alpha
chr5_+_9382301 0.90 ENSDART00000124017
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr5_+_30699260 0.89 ENSDART00000012888
atp5l
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g
chr18_+_45990394 0.88 ENSDART00000024068
mmp23bb
matrix metallopeptidase 23bb
chr24_-_28243186 0.87 ENSDART00000105691
cox4i1l
cytochrome c oxidase subunit IV isoform 1, like
chr8_-_37328112 0.86 ENSDART00000140365
slc12a5b
solute carrier family 12 (potassium/chloride transporter), member 5b
chr10_-_22249444 0.85 ENSDART00000148831
fgf11b
fibroblast growth factor 11b
chr1_-_38709551 0.85 ENSDART00000128794
gpm6ab
glycoprotein M6Ab
chr12_+_24561832 0.85 ENSDART00000088159
nrxn1a
neurexin 1a
chr24_-_38110779 0.84 ENSDART00000147783
crp
c-reactive protein, pentraxin-related
chr23_-_35064785 0.84 ENSDART00000172240
BX294434.1

chr7_+_23495986 0.83 ENSDART00000190739
ENSDART00000115299
ENSDART00000101423
ENSDART00000142401
zgc:109889
zgc:109889
chr15_-_12229874 0.83 ENSDART00000165159
dscaml1
Down syndrome cell adhesion molecule like 1
chr2_-_36818132 0.82 ENSDART00000110447
slitrk3b
SLIT and NTRK-like family, member 3b
chr25_-_37501371 0.82 ENSDART00000160498
CABZ01088346.1

chr16_+_1803462 0.82 ENSDART00000183974
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr9_-_18877597 0.82 ENSDART00000099446
kctd4
potassium channel tetramerization domain containing 4
chr13_+_23677949 0.82 ENSDART00000144215
pcnxl2
pecanex-like 2 (Drosophila)
chr7_-_19043401 0.81 ENSDART00000158796
fcer1g
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr16_+_10918252 0.80 ENSDART00000172949
pou2f2a
POU class 2 homeobox 2a
chr3_-_33417826 0.80 ENSDART00000084284
abi3a
ABI family, member 3a
chr25_+_4750972 0.79 ENSDART00000168903
si:zfos-2372e4.1
si:zfos-2372e4.1
chr5_+_36614196 0.77 ENSDART00000150574
nova1
neuro-oncological ventral antigen 1
chr15_-_30832897 0.77 ENSDART00000152330
msi2b
musashi RNA-binding protein 2b
chr20_-_51727860 0.75 ENSDART00000147044
brox
BRO1 domain and CAAX motif containing
chr24_-_21674950 0.75 ENSDART00000123216
ENSDART00000046211
lnx2a
ligand of numb-protein X 2a
chr5_-_19052184 0.74 ENSDART00000133330
fam214b
family with sequence similarity 214, member B
chr2_+_51783120 0.74 ENSDART00000177559
crygn1
crystallin, gamma N1
chr7_-_57949117 0.73 ENSDART00000138803
ank2b
ankyrin 2b, neuronal
chr2_+_28889936 0.73 ENSDART00000078232
cdh10a
cadherin 10, type 2a (T2-cadherin)
chr24_-_28381404 0.73 ENSDART00000148406
prkag2a
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr11_+_6650966 0.72 ENSDART00000131236
si:dkey-246j7.1
si:dkey-246j7.1
chr12_+_2522642 0.72 ENSDART00000152567
frmpd2
FERM and PDZ domain containing 2
chr23_+_42434348 0.72 ENSDART00000161027
cyp2aa1
cytochrome P450, family 2, subfamily AA, polypeptide 1
chr21_+_11244068 0.71 ENSDART00000163432
arid6
AT-rich interaction domain 6
chr24_+_15020402 0.69 ENSDART00000148102
dok6
docking protein 6
chr25_+_25464630 0.68 ENSDART00000150537
rassf7a
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7a
chr5_+_6892195 0.68 ENSDART00000048201
gb:cr929477
expressed sequence CR929477
chr2_-_23004286 0.65 ENSDART00000134664
ENSDART00000110373
ENSDART00000185833
ENSDART00000187235
znf414
mllt1b
zinc finger protein 414
MLLT1, super elongation complex subunit b
chr2_+_22694382 0.65 ENSDART00000139196
kif1ab
kinesin family member 1Ab
chr13_-_29505604 0.65 ENSDART00000110005
cdhr1a
cadherin-related family member 1a
chr1_-_46632948 0.64 ENSDART00000148893
ENSDART00000053232
cdadc1
cytidine and dCMP deaminase domain containing 1
chr9_-_704667 0.64 ENSDART00000147092
cflarb
CASP8 and FADD-like apoptosis regulator b
chr24_+_41931585 0.64 ENSDART00000130310
epb41l3a
erythrocyte membrane protein band 4.1-like 3a
chr12_-_22540943 0.64 ENSDART00000172310
zbtb4
zinc finger and BTB domain containing 4
chr21_+_5635420 0.64 ENSDART00000168158
shroom3
shroom family member 3
chr6_+_58492201 0.63 ENSDART00000156375
kcnq2b
potassium voltage-gated channel, KQT-like subfamily, member 2b
chr14_-_2369849 0.62 ENSDART00000180422
ENSDART00000189731
ENSDART00000111748
pcdhb
protocadherin b
chr2_+_3595333 0.61 ENSDART00000041052
c1ql3b
complement component 1, q subcomponent-like 3b
chr9_-_54001502 0.61 ENSDART00000085253
mid1
midline 1
chr23_-_41651759 0.61 ENSDART00000146808
si:ch73-184c24.1
si:ch73-184c24.1
chr2_+_58221163 0.60 ENSDART00000157939
FO704813.1

chr21_+_7823146 0.60 ENSDART00000030579
crhbp
corticotropin releasing hormone binding protein
chr16_-_17586883 0.60 ENSDART00000017142
m6pr
mannose-6-phosphate receptor (cation dependent)
chr8_+_36803415 0.59 ENSDART00000111680
iqsec2b
IQ motif and Sec7 domain 2b
chr18_+_41232719 0.59 ENSDART00000138552
ENSDART00000145863
trip12
thyroid hormone receptor interactor 12
chr9_+_7358749 0.59 ENSDART00000081660
ihha
Indian hedgehog homolog a
chr15_-_10455438 0.59 ENSDART00000158958
ENSDART00000192971
ENSDART00000162133
ENSDART00000185071
ENSDART00000192444
ENSDART00000165668
ENSDART00000175825
tenm4
teneurin transmembrane protein 4
chr9_-_43073960 0.58 ENSDART00000059460
ttn.2
titin, tandem duplicate 2
chr1_-_42779075 0.58 ENSDART00000133917
lrrtm1
leucine rich repeat transmembrane neuronal 1
chr5_-_70625697 0.58 ENSDART00000179538
ENSDART00000190540
CABZ01075572.1

chr16_+_9713850 0.58 ENSDART00000164103
ecm1b
extracellular matrix protein 1b
chr12_+_35203091 0.57 ENSDART00000153022
ndst2b
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b
chr5_-_41841675 0.57 ENSDART00000141683
si:dkey-65b12.6
si:dkey-65b12.6
chr25_+_3788074 0.57 ENSDART00000154008
chid1
chitinase domain containing 1
chr21_-_22485847 0.56 ENSDART00000162860
myo5b
myosin VB
chr22_+_28446365 0.56 ENSDART00000189359
abi3bpb
ABI family, member 3 (NESH) binding protein b
chr16_-_41439659 0.55 ENSDART00000191624
cpne4a
copine IVa
chr23_-_17470146 0.55 ENSDART00000002398
trim101
tripartite motif containing 101
chr7_-_35126374 0.55 ENSDART00000141211
hsd11b2
hydroxysteroid (11-beta) dehydrogenase 2
chr9_+_5862040 0.54 ENSDART00000129117
pdzk1
PDZ domain containing 1
chr2_-_4496358 0.53 ENSDART00000158216
adipoqb
adiponectin, C1Q and collagen domain containing, b
chr25_+_3788443 0.53 ENSDART00000189747
chid1
chitinase domain containing 1
chr5_-_71838520 0.53 ENSDART00000174396
CU927890.1

chr18_-_7810214 0.53 ENSDART00000139505
ENSDART00000139188
shank3a
SH3 and multiple ankyrin repeat domains 3a
chr19_-_10043142 0.52 ENSDART00000193016
grin2da
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, a
chr21_-_10488379 0.52 ENSDART00000163878
hcn1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr18_-_19350792 0.52 ENSDART00000147902
megf11
multiple EGF-like-domains 11
chr11_-_41130239 0.51 ENSDART00000173268
dnajc11b
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr3_-_59981162 0.50 ENSDART00000128790
cdr2l
cerebellar degeneration-related protein 2-like
chr15_+_3284416 0.49 ENSDART00000187665
ENSDART00000171723
foxo1a
forkhead box O1 a
chr8_-_23578660 0.49 ENSDART00000039080
wasb
Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b
chr13_-_29505946 0.49 ENSDART00000026679
cdhr1a
cadherin-related family member 1a
chr12_+_42436328 0.49 ENSDART00000167324
ebf3a
early B cell factor 3a
chr8_-_5847533 0.48 ENSDART00000192489
CABZ01102147.1

chr8_+_26268100 0.48 ENSDART00000138882
slc26a6
solute carrier family 26, member 6
chr20_-_37629084 0.48 ENSDART00000141734
hivep2a
human immunodeficiency virus type I enhancer binding protein 2a
chr11_+_12052791 0.47 ENSDART00000158479
si:ch211-156l18.8
si:ch211-156l18.8
chr21_-_15046065 0.47 ENSDART00000178507
mmp17a
matrix metallopeptidase 17a
chr13_-_27767330 0.47 ENSDART00000131631
ENSDART00000112553
ENSDART00000189911
rims1a
regulating synaptic membrane exocytosis 1a
chr16_+_47428721 0.47 ENSDART00000180597
ENSDART00000032309
slc25a32b
solute carrier family 25 (mitochondrial folate carrier), member 32b
chr8_+_46010838 0.47 ENSDART00000143126
si:ch211-119d14.2
si:ch211-119d14.2
chr20_+_50184934 0.47 ENSDART00000158388
slc24a4b
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4b
chr10_+_24445698 0.46 ENSDART00000146370
slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr1_-_42778510 0.46 ENSDART00000190172
lrrtm1
leucine rich repeat transmembrane neuronal 1
chr20_-_25669813 0.46 ENSDART00000153118
si:dkeyp-117h8.2
si:dkeyp-117h8.2
chr8_+_28900689 0.46 ENSDART00000141634
grid2
glutamate receptor, ionotropic, delta 2
chr19_-_25519310 0.46 ENSDART00000089882
C1GALT1 (1 of many)
si:dkey-202e17.1
chr15_+_42767803 0.45 ENSDART00000164879
slc8a2b
solute carrier family 8 (sodium/calcium exchanger), member 2b
chr20_-_42100932 0.45 ENSDART00000191930
slc35f1
solute carrier family 35, member F1
chr11_-_9808356 0.45 ENSDART00000167465
nlgn1
neuroligin 1
chr16_+_10963602 0.45 ENSDART00000141032
pou2f2a
POU class 2 homeobox 2a
chr22_+_28446557 0.45 ENSDART00000089546
abi3bpb
ABI family, member 3 (NESH) binding protein b
chr10_-_25543227 0.44 ENSDART00000007778
grik1a
glutamate receptor, ionotropic, kainate 1a
chr9_+_29585943 0.44 ENSDART00000185989
ENSDART00000115290
mcf2lb
mcf.2 cell line derived transforming sequence-like b
chr18_-_42333428 0.44 ENSDART00000034225
cntn5
contactin 5
chr3_-_59981476 0.44 ENSDART00000035878
ENSDART00000124038
cdr2l
cerebellar degeneration-related protein 2-like
chr17_-_8976307 0.44 ENSDART00000092113
zranb1b
zinc finger, RAN-binding domain containing 1b
chr17_+_5846202 0.42 ENSDART00000189713
fndc4b
fibronectin type III domain containing 4b
chr12_-_47899497 0.42 ENSDART00000162219
QRFPR
pyroglutamylated RFamide peptide receptor
chr5_-_30074332 0.42 ENSDART00000147963
bco2a
beta-carotene oxygenase 2a
chr6_-_13498745 0.41 ENSDART00000027684
ENSDART00000189438
mylkb
myosin light chain kinase b
chr23_-_524780 0.41 ENSDART00000055139
col9a3
collagen, type IX, alpha 3
chr17_-_22062364 0.40 ENSDART00000114470
ttbk1b
tau tubulin kinase 1b
chr12_+_35070085 0.40 ENSDART00000190603
syt15
synaptotagmin XV
chr19_-_25519612 0.40 ENSDART00000133150
C1GALT1 (1 of many)
si:dkey-202e17.1
chr17_-_2811992 0.39 ENSDART00000067543
gpr65
G protein-coupled receptor 65
chr6_-_43677125 0.38 ENSDART00000150128
foxp1b
forkhead box P1b
chr10_-_24961310 0.38 ENSDART00000037303
si:ch211-214k5.3
si:ch211-214k5.3
chr11_-_4235811 0.37 ENSDART00000121716
si:ch211-236d3.4
si:ch211-236d3.4
chr8_-_20230559 0.37 ENSDART00000193677
mllt1a
MLLT1, super elongation complex subunit a
chr5_-_30080332 0.37 ENSDART00000140049
bco2a
beta-carotene oxygenase 2a
chr12_+_36092218 0.37 ENSDART00000168694
btbd17a
BTB (POZ) domain containing 17a
chr4_+_74554605 0.37 ENSDART00000009653
kcna1b
potassium voltage-gated channel, shaker-related subfamily, member 1b
chr12_-_7854216 0.37 ENSDART00000149594
ank3b
ankyrin 3b
chr16_+_32152612 0.36 ENSDART00000008880
gprc6a
G protein-coupled receptor, class C, group 6, member A
chr5_-_24642026 0.36 ENSDART00000139522
si:ch211-106a19.1
si:ch211-106a19.1
chr25_-_11088839 0.36 ENSDART00000154748
sv2bb
synaptic vesicle glycoprotein 2Bb
chr20_-_20610812 0.36 ENSDART00000181870
ppm1ab
protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
chr18_-_46882649 0.35 ENSDART00000192056
gramd1bb
GRAM domain containing 1Bb
chr13_-_8776474 0.35 ENSDART00000122371
STPG4
si:ch211-93n23.7
chr8_-_31393429 0.34 ENSDART00000192369
nim1k
NIM1 serine/threonine protein kinase
chr21_-_11820379 0.34 ENSDART00000126640
RHOBTB3
si:dkey-6b12.5
chr4_+_3980247 0.34 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr3_+_52467879 0.34 ENSDART00000156039
adgre5a
adhesion G protein-coupled receptor E5a
chr20_-_42102416 0.34 ENSDART00000186378
ENSDART00000188253
ENSDART00000186458
slc35f1
solute carrier family 35, member F1
chr10_-_39283883 0.34 ENSDART00000023831
cry5
cryptochrome circadian clock 5
chr11_-_7078392 0.33 ENSDART00000112156
ENSDART00000188556
si:ch211-253b8.5
si:ch211-253b8.5
chr25_-_19395476 0.33 ENSDART00000182622
map1ab
microtubule-associated protein 1Ab
chr1_+_7414318 0.33 ENSDART00000127426
si:ch73-383l1.1
si:ch73-383l1.1
chr7_-_72426484 0.33 ENSDART00000190063
rph3ab
rabphilin 3A homolog (mouse), b
chr2_-_44183451 0.32 ENSDART00000111246
cadm3
cell adhesion molecule 3
chr9_+_8942258 0.32 ENSDART00000138836
ankrd10b
ankyrin repeat domain 10b
chr6_+_54239625 0.32 ENSDART00000149542
pacsin1b
protein kinase C and casein kinase substrate in neurons 1b
chr19_+_32257472 0.32 ENSDART00000186471
atxn1a
ataxin 1a
chr3_+_36972586 0.31 ENSDART00000102784
si:ch211-18i17.2
si:ch211-18i17.2
chr17_+_3379673 0.31 ENSDART00000176354
sntg2
syntrophin, gamma 2
chr10_+_42159471 0.30 ENSDART00000122160
CR925773.1

Network of associatons between targets according to the STRING database.

First level regulatory network of znf740b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0050996 positive regulation of lipid catabolic process(GO:0050996)
0.4 1.5 GO:0006837 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
0.3 1.2 GO:0015677 copper ion import(GO:0015677)
0.2 0.9 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.2 0.6 GO:0060031 mediolateral intercalation(GO:0060031)
0.2 0.6 GO:0090278 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.2 2.3 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.7 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.6 GO:0003242 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 2.4 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.1 1.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.2 GO:1904861 excitatory synapse assembly(GO:1904861)
0.1 0.7 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 0.6 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 2.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.6 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 1.4 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.4 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.8 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.6 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 1.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 1.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.5 GO:0034650 cortisol metabolic process(GO:0034650)
0.1 2.4 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 4.2 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 2.0 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.1 0.5 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 0.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 3.2 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1 0.9 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.8 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.5 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 1.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.3 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.5 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 1.8 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.3 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.3 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.4 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.2 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.0 0.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.6 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.4 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.9 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 0.2 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 1.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 2.0 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.6 GO:0001843 neural tube closure(GO:0001843)
0.0 0.3 GO:0042493 response to drug(GO:0042493)
0.0 0.3 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.6 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.0 0.4 GO:1903707 negative regulation of hemopoiesis(GO:1903707)
0.0 0.1 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 1.2 GO:0006414 translational elongation(GO:0006414)
0.0 4.0 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.2 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.2 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 1.3 GO:0007605 sensory perception of sound(GO:0007605)
0.0 1.6 GO:0006909 phagocytosis(GO:0006909)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.9 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 1.4 GO:0060027 convergent extension involved in gastrulation(GO:0060027)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0042584 chromaffin granule membrane(GO:0042584)
0.3 1.9 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.3 0.8 GO:0032997 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.2 2.2 GO:1990246 uniplex complex(GO:1990246)
0.1 4.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 1.8 GO:0031209 SCAR complex(GO:0031209)
0.1 2.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.6 GO:0043194 axon initial segment(GO:0043194)
0.1 0.9 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 0.8 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 2.2 GO:0035869 ciliary transition zone(GO:0035869)
0.1 0.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.2 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.0 0.5 GO:0061617 MICOS complex(GO:0061617)
0.0 0.7 GO:0030315 T-tubule(GO:0030315)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0033270 paranode region of axon(GO:0033270) juxtaparanode region of axon(GO:0044224)
0.0 0.8 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 2.8 GO:0045177 apical part of cell(GO:0045177)
0.0 2.1 GO:0005884 actin filament(GO:0005884)
0.0 0.8 GO:0030175 filopodium(GO:0030175)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.5 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.3 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.7 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0070186 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.5 1.5 GO:0005335 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.5 1.5 GO:0031716 calcitonin receptor binding(GO:0031716)
0.4 1.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 1.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 0.8 GO:0019763 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
0.2 1.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 0.9 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 0.5 GO:0008517 folic acid transporter activity(GO:0008517)
0.2 2.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 3.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.4 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 4.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.3 GO:0003913 DNA photolyase activity(GO:0003913)
0.1 2.0 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.6 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.8 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 1.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 1.1 GO:0008061 chitin binding(GO:0008061)
0.1 0.5 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.6 GO:0005113 patched binding(GO:0005113)
0.1 0.8 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 0.2 GO:0004945 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.1 0.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 3.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 1.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.9 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 2.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.2 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.9 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0030552 cAMP binding(GO:0030552)
0.0 1.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.7 GO:0016208 AMP binding(GO:0016208)
0.0 1.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 1.2 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.4 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 0.6 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.8 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 2.0 GO:0015293 symporter activity(GO:0015293)
0.0 0.0 GO:0072571 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.0 0.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0051117 ATPase binding(GO:0051117)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 0.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 2.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.8 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 0.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 0.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.5 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.9 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions