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PRJNA195909:zebrafish embryo and larva development

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Results for CABZ01087224.1+hlfb

Z-value: 0.59

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Transcription factors associated with CABZ01087224.1+hlfb

Gene Symbol Gene ID Gene Info
hlfb
ENSDARG00000061011 HLF transcription factor, PAR bZIP family member b
CABZ01087224.1
ENSDARG00000111269 ENSDARG00000111269

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hlfbdr11_v1_chr12_+_32159272_32159272-0.909.5e-04Click!
CABZ01087224.1dr11_v1_chr3_+_11568523_115685230.206.0e-01Click!

Activity profile of CABZ01087224.1+hlfb motif

Sorted Z-values of CABZ01087224.1+hlfb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_22974019 1.24 ENSDART00000147157
ENSDART00000020434
brwd3
bromodomain and WD repeat domain containing 3
chr16_-_29387215 1.01 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr25_+_36292465 0.88 ENSDART00000152649
bmb
brambleberry
chr22_+_10606573 0.86 ENSDART00000192638
rad54l2
RAD54 like 2
chr17_-_17759138 0.83 ENSDART00000157128
ENSDART00000123845
adck1
aarF domain containing kinase 1
chr9_-_12888082 0.82 ENSDART00000133135
ENSDART00000134415
si:ch211-167j6.3
si:ch211-167j6.3
chr23_-_12453700 0.79 ENSDART00000091140
snx21
sorting nexin family member 21
chr19_+_14109348 0.71 ENSDART00000159015
zgc:175136
zgc:175136
chr7_+_46020508 0.68 ENSDART00000170294
ccne1
cyclin E1
chr13_-_10620652 0.67 ENSDART00000135000
ENSDART00000191587
si:ch73-54n14.2
camkmt
si:ch73-54n14.2
calmodulin-lysine N-methyltransferase
chr22_+_10606863 0.64 ENSDART00000147975
rad54l2
RAD54 like 2
chr3_+_7763114 0.63 ENSDART00000057434
hook2
hook microtubule-tethering protein 2
chr20_-_33966148 0.61 ENSDART00000148111
selp
selectin P
chr7_+_15736230 0.57 ENSDART00000109942
mctp2b
multiple C2 domains, transmembrane 2b
chr4_+_5196469 0.57 ENSDART00000067386
rad51ap1
RAD51 associated protein 1
chr3_+_41731527 0.57 ENSDART00000049007
ENSDART00000187866
chst12a
carbohydrate (chondroitin 4) sulfotransferase 12a
chr20_-_35508805 0.55 ENSDART00000169538
adgrf3b
adhesion G protein-coupled receptor F3b
chr20_+_1272526 0.54 ENSDART00000008115
ENSDART00000133825
hsd3b2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr2_+_44518636 0.54 ENSDART00000153733
pask
PAS domain containing serine/threonine kinase
chr5_-_30074332 0.54 ENSDART00000147963
bco2a
beta-carotene oxygenase 2a
chr23_-_18030399 0.53 ENSDART00000136967
pm20d1.1
peptidase M20 domain containing 1, tandem duplicate 1
chr14_-_30905288 0.52 ENSDART00000173449
ENSDART00000173451
si:ch211-126c2.4
si:ch211-126c2.4
chr13_-_25408387 0.52 ENSDART00000002741
itprip
inositol 1,4,5-trisphosphate receptor interacting protein
chr1_-_354115 0.51 ENSDART00000141590
ENSDART00000098627
pros1
protein S
chr22_+_15973122 0.50 ENSDART00000144545
rc3h1a
ring finger and CCCH-type domains 1a
chr15_-_24960730 0.50 ENSDART00000109990
ENSDART00000186706
abhd15a
abhydrolase domain containing 15a
chr7_+_38380135 0.50 ENSDART00000174005
rhpn2
rhophilin, Rho GTPase binding protein 2
chr7_+_46019780 0.49 ENSDART00000163991
ccne1
cyclin E1
chr6_-_4228640 0.49 ENSDART00000162497
ENSDART00000179923
trak2
trafficking protein, kinesin binding 2
chr10_+_6884123 0.48 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr16_+_47207691 0.48 ENSDART00000062507
ica1
islet cell autoantigen 1
chr15_-_1885247 0.48 ENSDART00000149703
porb
P450 (cytochrome) oxidoreductase b
chr2_-_55779927 0.47 ENSDART00000168579
CABZ01066725.1

chr5_-_33236637 0.46 ENSDART00000085512
ENSDART00000144694
kank1b
KN motif and ankyrin repeat domains 1b
chr18_+_25546227 0.46 ENSDART00000085824
pex11a
peroxisomal biogenesis factor 11 alpha
chr8_+_247163 0.46 ENSDART00000122378
cep120
centrosomal protein 120
chr23_-_33361425 0.46 ENSDART00000031638
slc48a1a
solute carrier family 48 (heme transporter), member 1a
chr19_+_7549854 0.46 ENSDART00000138866
ENSDART00000151758
pbxip1a
pre-B-cell leukemia homeobox interacting protein 1a
chr20_-_48877458 0.46 ENSDART00000163271
xrn2
5'-3' exoribonuclease 2
chr17_-_25831569 0.45 ENSDART00000148743
hhat
hedgehog acyltransferase
chr6_-_32411703 0.45 ENSDART00000151002
ENSDART00000078908
usp1
ubiquitin specific peptidase 1
chr19_-_24757231 0.45 ENSDART00000128177
si:dkey-154b15.1
si:dkey-154b15.1
chr17_+_26722904 0.44 ENSDART00000114927
nrde2
NRDE-2, necessary for RNA interference, domain containing
chr5_-_68782641 0.43 ENSDART00000141699
mepce
methylphosphate capping enzyme
chr4_+_11690923 0.43 ENSDART00000150624
mkln1
muskelin 1, intracellular mediator containing kelch motifs
chr21_+_43178831 0.43 ENSDART00000151512
aff4
AF4/FMR2 family, member 4
chr21_+_17051478 0.42 ENSDART00000047201
ENSDART00000161650
ENSDART00000167298
atp2a2a
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr5_-_11809404 0.41 ENSDART00000132564
nf2a
neurofibromin 2a (merlin)
chr18_-_43866526 0.41 ENSDART00000111309
treh
trehalase (brush-border membrane glycoprotein)
chr23_-_29812667 0.41 ENSDART00000006120
pik3cd
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
chr2_-_4070850 0.40 ENSDART00000159990
yme1l1b
YME1-like 1b
chr7_+_22853788 0.39 ENSDART00000148502
clcn5b
chloride channel, voltage-sensitive 5b
chr2_-_17115256 0.39 ENSDART00000190488
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr5_-_54395488 0.39 ENSDART00000160781
zmynd19
zinc finger, MYND-type containing 19
chr15_-_20412286 0.39 ENSDART00000008589
chp2
calcineurin-like EF-hand protein 2
chr2_+_35603637 0.39 ENSDART00000147278
plk3
polo-like kinase 3 (Drosophila)
chr14_+_3507326 0.39 ENSDART00000159326
gstp1
glutathione S-transferase pi 1
chr19_+_43715911 0.38 ENSDART00000006344
cap1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr3_+_19687217 0.38 ENSDART00000141937
tlk2
tousled-like kinase 2
chr6_+_10333920 0.38 ENSDART00000151667
ENSDART00000151477
cobll1a
cordon-bleu WH2 repeat protein-like 1a
chr16_+_40954481 0.37 ENSDART00000058587
gbp
glycogen synthase kinase binding protein
chr19_-_3056235 0.37 ENSDART00000137020
bop1
block of proliferation 1
chr2_-_19234329 0.36 ENSDART00000161106
ENSDART00000160060
ENSDART00000174552
cdc20
cell division cycle 20 homolog
chr6_+_37754763 0.36 ENSDART00000110770
herc2
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr5_+_13870340 0.35 ENSDART00000160690
hk2
hexokinase 2
chr2_-_10563576 0.35 ENSDART00000185818
ENSDART00000190887
ccdc18
coiled-coil domain containing 18
chr13_-_35472531 0.35 ENSDART00000057052
slx4ip
SLX4 interacting protein
chr12_-_34258384 0.35 ENSDART00000109196
pgs1
phosphatidylglycerophosphate synthase 1
chr3_-_26183699 0.35 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
si:ch211-11k18.4
chr3_-_30885250 0.35 ENSDART00000109104
kmt5c
lysine methyltransferase 5C
chr20_-_33675676 0.35 ENSDART00000147168
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr2_+_16597011 0.35 ENSDART00000160641
ENSDART00000125413
xrn1
5'-3' exoribonuclease 1
chr24_-_26854032 0.35 ENSDART00000087991
fndc3bb
fibronectin type III domain containing 3Bb
chr1_-_45616242 0.35 ENSDART00000150066
atf7ip
activating transcription factor 7 interacting protein
chr6_+_8314451 0.34 ENSDART00000147793
ENSDART00000183688
gcdha
glutaryl-CoA dehydrogenase a
chr15_+_12435975 0.34 ENSDART00000168011
tmprss4a
transmembrane protease, serine 4a
chr23_-_35396845 0.34 ENSDART00000142038
ENSDART00000049373
ENSDART00000181978
ENSDART00000171357
cmtr1
cap methyltransferase 1
chr18_+_8917766 0.34 ENSDART00000145226
si:ch211-233h19.2
si:ch211-233h19.2
chr7_+_38090515 0.34 ENSDART00000131387
cebpg
CCAAT/enhancer binding protein (C/EBP), gamma
chr9_+_38168012 0.34 ENSDART00000102445
clasp1a
cytoplasmic linker associated protein 1a
chr9_-_29321625 0.34 ENSDART00000158689
ENSDART00000014047
ENSDART00000122602
pth2r
parathyroid hormone 2 receptor
chr21_+_18907102 0.33 ENSDART00000160185
ENSDART00000190175
ENSDART00000017937
ENSDART00000191546
ENSDART00000130519
ENSDART00000137143
smpd4
sphingomyelin phosphodiesterase 4
chr5_+_27137473 0.33 ENSDART00000181833
unc5db
unc-5 netrin receptor Db
chr21_-_32781612 0.33 ENSDART00000031028
cnot6a
CCR4-NOT transcription complex, subunit 6a
chr8_+_26874924 0.33 ENSDART00000141794
rimkla
ribosomal modification protein rimK-like family member A
chr20_-_23876291 0.33 ENSDART00000043316
katna1
katanin p60 (ATPase containing) subunit A 1
chr2_-_10564019 0.33 ENSDART00000132167
ccdc18
coiled-coil domain containing 18
chr18_+_17493859 0.33 ENSDART00000090754
si:dkey-102f14.5
si:dkey-102f14.5
chr7_+_73295890 0.32 ENSDART00000174331
ENSDART00000174250
CABZ01083442.1

chr3_+_25907266 0.32 ENSDART00000170324
ENSDART00000192633
tom1
target of myb1 membrane trafficking protein
chr2_-_37277626 0.32 ENSDART00000135340
nadkb
NAD kinase b
chr14_-_30905963 0.32 ENSDART00000183543
ENSDART00000186441
si:ch211-126c2.4
si:ch211-126c2.4
chr11_+_43751263 0.32 ENSDART00000163843
zgc:153431
zgc:153431
chr1_+_12394205 0.31 ENSDART00000138622
ENSDART00000136421
ENSDART00000139440
ENSDART00000184296
ENSDART00000008127
zgc:77739
zgc:77739
chr2_+_9757453 0.31 ENSDART00000168972
pcyt1aa
phosphate cytidylyltransferase 1, choline, alpha a
chr18_-_14879135 0.31 ENSDART00000099701
selenoo1
selenoprotein O1
chr18_-_15551360 0.31 ENSDART00000159915
ENSDART00000172690
ppfibp1b
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr20_-_20355577 0.31 ENSDART00000018500
hif1ab
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b
chr6_-_7726849 0.31 ENSDART00000151511
slc25a38b
solute carrier family 25, member 38b
chr3_-_40275096 0.31 ENSDART00000141578
shmt1
serine hydroxymethyltransferase 1 (soluble)
chr3_-_26184018 0.31 ENSDART00000191604
si:ch211-11k18.4
si:ch211-11k18.4
chr17_+_25833947 0.30 ENSDART00000044328
ENSDART00000154604
acss1
acyl-CoA synthetase short chain family member 1
chr5_-_14521500 0.30 ENSDART00000176565
si:ch211-244o22.2
si:ch211-244o22.2
chr8_-_53044300 0.30 ENSDART00000191653
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr23_+_19213472 0.30 ENSDART00000185985
apobec2b
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2b
chr19_+_42227400 0.30 ENSDART00000131574
ENSDART00000135436
jtb
jumping translocation breakpoint
chr9_+_21306902 0.30 ENSDART00000138554
ENSDART00000004108
xpo4
exportin 4
chr10_+_23099890 0.30 ENSDART00000135890
LTN1
si:dkey-175g6.5
chr3_+_14463941 0.30 ENSDART00000170927
cnn1b
calponin 1, basic, smooth muscle, b
chr17_+_17764979 0.30 ENSDART00000105013
alkbh1
alkB homolog 1, histone H2A dioxygenase
chr18_-_39288894 0.30 ENSDART00000186216
mapk6
mitogen-activated protein kinase 6
chr23_-_25686894 0.30 ENSDART00000181420
ENSDART00000088208
lrp1ab
low density lipoprotein receptor-related protein 1Ab
chr20_+_1121458 0.30 ENSDART00000064472
pnrc1
proline-rich nuclear receptor coactivator 1
chr16_-_30864824 0.30 ENSDART00000190444
ENSDART00000192231
ptk2ab
protein tyrosine kinase 2ab
chr19_+_15441022 0.30 ENSDART00000098970
ENSDART00000140276
lin28a
lin-28 homolog A (C. elegans)
chr12_+_34854562 0.29 ENSDART00000130366
si:dkey-21c1.4
si:dkey-21c1.4
chr13_-_25196758 0.29 ENSDART00000184722
adka
adenosine kinase a
chr20_-_38746889 0.29 ENSDART00000140275
trim54
tripartite motif containing 54
chr21_+_1647990 0.29 ENSDART00000148540
fech
ferrochelatase
chr16_+_35728992 0.29 ENSDART00000158442
map7d1a
MAP7 domain containing 1a
chr9_-_32300783 0.29 ENSDART00000078596
hspd1
heat shock 60 protein 1
chr6_+_23810529 0.29 ENSDART00000166921
glulb
glutamate-ammonia ligase (glutamine synthase) b
chr12_-_23365737 0.29 ENSDART00000170376
mpp7a
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr3_+_43373867 0.29 ENSDART00000159455
ENSDART00000172425
zfand2a
zinc finger, AN1-type domain 2A
chr20_-_36617313 0.29 ENSDART00000172395
ENSDART00000152856
enah
enabled homolog (Drosophila)
chr13_-_15142280 0.29 ENSDART00000163132
rab11fip5a
RAB11 family interacting protein 5a (class I)
chr23_+_9522781 0.29 ENSDART00000136486
osbpl2b
oxysterol binding protein-like 2b
chr9_-_5318873 0.29 ENSDART00000129308
ACVR1C
activin A receptor type 1C
chr24_-_23784701 0.29 ENSDART00000090368
sgk3
serum/glucocorticoid regulated kinase family, member 3
chr1_-_58887610 0.28 ENSDART00000180647
CABZ01084501.1
microfibril-associated glycoprotein 4-like precursor
chr8_-_4010887 0.28 ENSDART00000163678
mtmr3
myotubularin related protein 3
chr8_+_26007988 0.28 ENSDART00000193948
ENSDART00000058100
xpc
xeroderma pigmentosum, complementation group C
chr19_-_30810328 0.28 ENSDART00000184875
myclb
MYCL proto-oncogene, bHLH transcription factor b
chr6_+_36381709 0.28 ENSDART00000004727
rhcgl1
Rh family, C glycoprotein, like 1
chr4_-_27099224 0.28 ENSDART00000048383
creld2
cysteine-rich with EGF-like domains 2
chr1_+_19764995 0.28 ENSDART00000138276
si:ch211-42i9.8
si:ch211-42i9.8
chr3_+_33440615 0.28 ENSDART00000146005
gtpbp1
GTP binding protein 1
chr8_+_12930216 0.28 ENSDART00000115405
KIF2A
zgc:103670
chr8_-_25846188 0.28 ENSDART00000128829
efhd2
EF-hand domain family, member D2
chr10_-_2875735 0.28 ENSDART00000034555
ddx56
DEAD (Asp-Glu-Ala-Asp) box helicase 56
chr15_+_24676905 0.27 ENSDART00000078014
ENSDART00000143137
poldip2
polymerase (DNA-directed), delta interacting protein 2
chr20_+_474288 0.27 ENSDART00000026794
nt5dc1
5'-nucleotidase domain containing 1
chr20_+_39250673 0.27 ENSDART00000153003
reps1
RALBP1 associated Eps domain containing 1
chr7_+_18176162 0.27 ENSDART00000109171
rce1a
Ras converting CAAX endopeptidase 1a
chr7_-_40959667 0.27 ENSDART00000084070
rbm33a
RNA binding motif protein 33a
chr13_-_14929236 0.27 ENSDART00000020576
cdc25b
cell division cycle 25B
chr1_+_16600690 0.27 ENSDART00000162164
mtus1b
microtubule associated tumor suppressor 1b
chr6_+_12326267 0.27 ENSDART00000155101
si:dkey-276j7.3
si:dkey-276j7.3
chr7_-_8961941 0.26 ENSDART00000111002
si:ch211-74f19.2
si:ch211-74f19.2
chr7_+_12950507 0.26 ENSDART00000067629
ENSDART00000158004
saa
serum amyloid A
chr19_-_30811161 0.26 ENSDART00000103524
myclb
MYCL proto-oncogene, bHLH transcription factor b
chr9_+_21268739 0.26 ENSDART00000186514
BX511129.3

chr9_-_18743012 0.26 ENSDART00000131626
tsc22d1
TSC22 domain family, member 1
chr13_+_30035253 0.26 ENSDART00000181303
ENSDART00000057525
ENSDART00000136622
dnajb12a
DnaJ (Hsp40) homolog, subfamily B, member 12a
chr4_-_17353972 0.26 ENSDART00000041529
parpbp
PARP1 binding protein
chr7_+_22792895 0.26 ENSDART00000184407
rbm4.3
RNA binding motif protein 4.3
chr21_+_38855551 0.25 ENSDART00000171977
ddx52
DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
chr6_+_18423402 0.25 ENSDART00000159747
rab11fip4b
RAB11 family interacting protein 4 (class II) b
chr2_+_30182431 0.25 ENSDART00000004903
rdh10b
retinol dehydrogenase 10b
chr25_-_12803723 0.25 ENSDART00000158787
ca5a
carbonic anhydrase Va
chr19_+_46259619 0.25 ENSDART00000158032
grinaa
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1a (glutamate binding)
chr14_-_30901602 0.25 ENSDART00000172925
si:ch211-126c2.4
si:ch211-126c2.4
chr22_-_17677947 0.25 ENSDART00000139911
tjp3
tight junction protein 3
chr4_+_5341592 0.25 ENSDART00000123375
ENSDART00000067371
zgc:113263
zgc:113263
chr9_-_27391908 0.25 ENSDART00000135221
nepro
nucleolus and neural progenitor protein
chr9_-_9225980 0.25 ENSDART00000180301
cbsb
cystathionine-beta-synthase b
chr18_+_5917625 0.25 ENSDART00000169100
glg1b
golgi glycoprotein 1b
chr12_+_48390715 0.25 ENSDART00000149351
scd
stearoyl-CoA desaturase (delta-9-desaturase)
chr24_+_26329018 0.25 ENSDART00000145752
mynn
myoneurin
chr9_-_13871935 0.24 ENSDART00000146597
raph1a
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr12_+_46869271 0.24 ENSDART00000166560
hpdl
4-hydroxyphenylpyruvate dioxygenase-like
chr13_-_42536642 0.24 ENSDART00000134533
btaf1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated
chr11_+_24820542 0.24 ENSDART00000135443
kdm5ba
lysine (K)-specific demethylase 5Ba
chr24_+_32525146 0.24 ENSDART00000132417
ENSDART00000110185
yme1l1a
YME1-like 1a
chr18_+_21951551 0.24 ENSDART00000146261
ranbp10
RAN binding protein 10
chr15_+_21882419 0.24 ENSDART00000157216
si:dkey-103g5.4
si:dkey-103g5.4
chr9_+_27720428 0.24 ENSDART00000112415
lcmt2
leucine carboxyl methyltransferase 2
chr12_+_32199651 0.24 ENSDART00000153027
si:ch211-277e21.1
si:ch211-277e21.1
chr16_-_35427060 0.24 ENSDART00000172294
ctps1b
CTP synthase 1b
chr21_-_32467099 0.24 ENSDART00000186354
zgc:123105
zgc:123105
chr9_+_22375779 0.24 ENSDART00000183956
dgkg
diacylglycerol kinase, gamma
chr6_+_8315050 0.24 ENSDART00000189987
gcdha
glutaryl-CoA dehydrogenase a
chr8_+_7801060 0.23 ENSDART00000161618
tfe3a
transcription factor binding to IGHM enhancer 3a
chr1_+_37312580 0.23 ENSDART00000171340
fam193a
family with sequence similarity 193, member A
chr13_-_44836727 0.23 ENSDART00000144385
si:dkeyp-2e4.3
si:dkeyp-2e4.3
chr13_+_15816573 0.23 ENSDART00000137061
klc1a
kinesin light chain 1a
chr7_-_46019756 0.23 ENSDART00000162583
zgc:162297
zgc:162297
chr5_+_27421639 0.23 ENSDART00000146285
cyb561a3a
cytochrome b561 family, member A3a
chr13_+_25396896 0.23 ENSDART00000041257
gsto2
glutathione S-transferase omega 2
chr17_-_5610514 0.23 ENSDART00000004043
enpp4
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr7_+_34297271 0.23 ENSDART00000180342
bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr5_-_4931266 0.23 ENSDART00000067600
zbtb43
zinc finger and BTB domain containing 43
chr13_+_25397098 0.23 ENSDART00000132953
gsto2
glutathione S-transferase omega 2
chr11_+_13176568 0.22 ENSDART00000125371
ENSDART00000123257
mknk1
MAP kinase interacting serine/threonine kinase 1
chr22_+_18816662 0.22 ENSDART00000132476
cbarpb
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr19_+_16016038 0.22 ENSDART00000131319
ctps1a
CTP synthase 1a
chr21_-_38618540 0.22 ENSDART00000036600
slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr17_+_51744450 0.22 ENSDART00000190955
ENSDART00000149807
odc1
ornithine decarboxylase 1
chr9_-_27720612 0.22 ENSDART00000000566
gtf2e1
general transcription factor IIE, polypeptide 1, alpha
chr5_+_36439405 0.22 ENSDART00000102973
eda
ectodysplasin A

Network of associatons between targets according to the STRING database.

First level regulatory network of CABZ01087224.1+hlfb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0000741 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.2 0.5 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.4 GO:1904871 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1 0.4 GO:0005991 trehalose metabolic process(GO:0005991)
0.1 0.5 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.1 0.5 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.5 GO:0032755 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.4 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.1 0.5 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.1 0.3 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.1 0.3 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 0.6 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.1 0.3 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.1 0.4 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.1 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.5 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 0.3 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 0.2 GO:0050666 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.1 0.2 GO:0070197 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.5 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 0.2 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 0.5 GO:0016559 peroxisome fission(GO:0016559)
0.1 0.2 GO:0001120 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.1 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.4 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 0.3 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 0.5 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.2 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.1 0.5 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.4 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 0.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.4 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.1 GO:0046655 folic acid metabolic process(GO:0046655)
0.1 0.3 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.1 0.3 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1 0.2 GO:2000374 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.1 0.3 GO:0071218 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.1 0.3 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.3 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.1 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.5 GO:0016119 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.3 GO:0044209 AMP salvage(GO:0044209)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.4 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.5 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.2 GO:0032208 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.0 0.4 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.0 0.3 GO:0051883 acute-phase response(GO:0006953) killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0050787 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.5 GO:0007190 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.2 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.2 GO:0050820 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.0 0.3 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.4 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.3 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.4 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.3 GO:0070309 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:0018063 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.0 0.6 GO:0008406 gonad development(GO:0008406)
0.0 0.4 GO:0009749 response to glucose(GO:0009749)
0.0 0.1 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.1 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 0.2 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.0 0.3 GO:0030104 water homeostasis(GO:0030104)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.8 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 1.3 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.4 GO:0048696 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.3 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.5 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 0.4 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.2 GO:2001270 regulation of execution phase of apoptosis(GO:1900117) negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.3 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.2 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.4 GO:0090559 regulation of membrane permeability(GO:0090559)
0.0 0.1 GO:0014005 microglia development(GO:0014005)
0.0 0.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.6 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.4 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.0 0.1 GO:0070589 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.0 1.2 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.4 GO:0006298 mismatch repair(GO:0006298)
0.0 0.3 GO:0007004 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.2 GO:0051877 chaperone-mediated protein complex assembly(GO:0051131) pigment granule aggregation in cell center(GO:0051877)
0.0 0.3 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.1 GO:0043576 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.0 0.3 GO:0002138 retinoic acid biosynthetic process(GO:0002138)
0.0 0.5 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.2 GO:0010878 cholesterol storage(GO:0010878) regulation of cholesterol storage(GO:0010885)
0.0 0.1 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.3 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.0 0.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.0 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.7 GO:0055088 lipid homeostasis(GO:0055088)
0.0 1.7 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.2 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.0 1.4 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.7 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.6 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0042026 protein refolding(GO:0042026)
0.0 0.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.6 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.1 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.0 0.3 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 0.5 GO:0097268 cytoophidium(GO:0097268)
0.1 0.4 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.3 GO:0070209 ASTRA complex(GO:0070209)
0.1 0.2 GO:1990745 EARP complex(GO:1990745)
0.1 0.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.4 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.2 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.2 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.2 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.0 0.7 GO:0070187 telosome(GO:0070187)
0.0 0.2 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.2 GO:0016586 RSC complex(GO:0016586)
0.0 0.2 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.5 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 1.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.5 GO:0043186 P granule(GO:0043186)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 2.5 GO:0005769 early endosome(GO:0005769)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.9 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.1 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.2 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.6 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.1 0.4 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
0.1 0.4 GO:0015927 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.1 0.5 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.2 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.1 0.5 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 0.4 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.3 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.1 0.3 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.1 0.3 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.7 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.2 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.1 0.4 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.3 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.1 0.6 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.4 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.1 0.5 GO:0034338 short-chain carboxylesterase activity(GO:0034338)
0.1 0.2 GO:0003913 DNA photolyase activity(GO:0003913)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.2 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.4 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.1 0.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.4 GO:0005536 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.3 GO:0004001 adenosine kinase activity(GO:0004001)
0.1 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.2 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.1 0.2 GO:0032405 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.1 0.2 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.1 0.3 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.5 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.2 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.0 0.5 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0015140 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.1 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.0 0.4 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.3 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.3 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.2 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.2 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.3 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.1 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.2 GO:0048018 death receptor binding(GO:0005123) receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.0 1.1 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.0 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.3 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.9 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.6 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 0.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 0.5 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.1 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.6 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis