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PRJNA195909:zebrafish embryo and larva development

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Results for SPDEF

Z-value: 1.87

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Transcription factors associated with SPDEF

Gene Symbol Gene ID Gene Info
SPDEF
ENSDARG00000029930 SAM pointed domain containing ETS transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPDEFdr11_v1_chr6_-_54290227_54290227-0.801.0e-02Click!

Activity profile of SPDEF motif

Sorted Z-values of SPDEF motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_3398383 3.47 ENSDART00000047865
si:dkey-46g23.2
si:dkey-46g23.2
chr3_-_3413669 3.43 ENSDART00000113517
ENSDART00000179861
ENSDART00000115331
zgc:171446
zgc:171446
chr21_-_43636595 2.56 ENSDART00000151115
ENSDART00000151486
ENSDART00000151778
si:ch1073-263o8.2
si:ch1073-263o8.2
chr15_+_38299385 2.53 ENSDART00000142403
si:dkey-24p1.6
si:dkey-24p1.6
chr8_+_23726708 2.42 ENSDART00000142395
mkrn4
makorin, ring finger protein, 4
chr5_+_6854345 2.10 ENSDART00000066307
elac1
elaC ribonuclease Z 1
chr15_+_38299563 2.06 ENSDART00000099375
si:dkey-24p1.6
si:dkey-24p1.6
chr12_-_9468618 2.05 ENSDART00000152737
ENSDART00000091519
pgap3
post-GPI attachment to proteins 3
chr18_+_6638974 1.95 ENSDART00000162398
c2cd5
C2 calcium-dependent domain containing 5
chr8_+_23726244 1.95 ENSDART00000132734
mkrn4
makorin, ring finger protein, 4
chr1_+_49435017 1.88 ENSDART00000124833
pdcd11
programmed cell death 11
chr18_+_6638726 1.85 ENSDART00000142755
ENSDART00000167781
c2cd5
C2 calcium-dependent domain containing 5
chr23_-_33775145 1.77 ENSDART00000132147
ENSDART00000027959
ENSDART00000160116
racgap1
Rac GTPase activating protein 1
chr6_+_4387150 1.74 ENSDART00000181283
rbm26
RNA binding motif protein 26
chr15_+_34933552 1.72 ENSDART00000155368
zgc:66024
zgc:66024
chr3_-_3372259 1.72 ENSDART00000140482
si:dkey-46g23.1
si:dkey-46g23.1
chr20_-_48898371 1.67 ENSDART00000170617
xrn2
5'-3' exoribonuclease 2
chr5_+_6854498 1.66 ENSDART00000148663
elac1
elaC ribonuclease Z 1
chr2_+_32846602 1.62 ENSDART00000056649
tmem53
transmembrane protein 53
chr2_+_51818039 1.61 ENSDART00000170353
acvr2bb
activin A receptor type 2Bb
chr20_-_48898560 1.53 ENSDART00000163071
xrn2
5'-3' exoribonuclease 2
chr2_+_30182431 1.51 ENSDART00000004903
rdh10b
retinol dehydrogenase 10b
chr8_+_48965767 1.49 ENSDART00000008058
aak1a
AP2 associated kinase 1a
chr15_+_25528290 1.48 ENSDART00000123143
npat
nuclear protein, ataxia-telangiectasia locus
chr25_+_8921425 1.48 ENSDART00000128591
accs
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
chr5_-_26795438 1.48 ENSDART00000146124
si:ch211-102c2.7
si:ch211-102c2.7
chr6_+_3334392 1.47 ENSDART00000133707
ENSDART00000130879
st3gal3a
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr8_+_48966165 1.43 ENSDART00000165425
aak1a
AP2 associated kinase 1a
chr22_-_5171362 1.41 ENSDART00000124889
tnfaip8l1
tumor necrosis factor, alpha-induced protein 8-like 1
chr20_+_13141408 1.38 ENSDART00000034098
dtl
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr17_-_7351488 1.37 ENSDART00000098731
stxbp5b
syntaxin binding protein 5b (tomosyn)
chr8_-_33154677 1.37 ENSDART00000133300
zbtb34
zinc finger and BTB domain containing 34
chr21_-_30994577 1.36 ENSDART00000065503
pgap2
post-GPI attachment to proteins 2
chr15_-_43625549 1.34 ENSDART00000168589
ctsc
cathepsin C
chr7_-_71384391 1.34 ENSDART00000112841
ccdc149a
coiled-coil domain containing 149a
chr8_+_17143501 1.34 ENSDART00000061758
mier3b
mesoderm induction early response 1, family member 3 b
chr17_+_8754020 1.32 ENSDART00000105322
edrf1
erythroid differentiation regulatory factor 1
chr1_+_24557414 1.29 ENSDART00000076519
dctpp1
dCTP pyrophosphatase 1
chr7_+_35191220 1.28 ENSDART00000110552
zdhhc1
zinc finger, DHHC-type containing 1
chr12_+_46543572 1.28 ENSDART00000167510
hid1b
HID1 domain containing b
chr20_-_39789036 1.27 ENSDART00000086405
ENSDART00000098253
rnf217
ring finger protein 217
chr8_+_30112655 1.27 ENSDART00000099027
fancc
Fanconi anemia, complementation group C
chr1_-_40519340 1.27 ENSDART00000114659
maml3
mastermind-like transcriptional coactivator 3
chr8_-_14080534 1.25 ENSDART00000042867
dedd
death effector domain containing
chr13_+_31545530 1.22 ENSDART00000164590
ENSDART00000178460
ENSDART00000185503
ppm1aa
protein phosphatase, Mg2+/Mn2+ dependent, 1Aa
chr17_+_8754426 1.21 ENSDART00000185519
edrf1
erythroid differentiation regulatory factor 1
chr22_+_8753092 1.20 ENSDART00000140720
si:dkey-182g1.2
si:dkey-182g1.2
chr18_+_3634652 1.18 ENSDART00000159913
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr13_+_31545812 1.17 ENSDART00000076527
ppm1aa
protein phosphatase, Mg2+/Mn2+ dependent, 1Aa
chr1_+_46598502 1.15 ENSDART00000132861
cab39l
calcium binding protein 39-like
chr24_-_41220538 1.15 ENSDART00000150207
acvr2ba
activin A receptor type 2Ba
chr22_+_8753365 1.14 ENSDART00000106086
si:dkey-182g1.2
si:dkey-182g1.2
chr20_-_23254876 1.14 ENSDART00000141510
ociad1
OCIA domain containing 1
chr20_+_27087539 1.14 ENSDART00000062094
tmem251
transmembrane protein 251
chr5_+_41477954 1.14 ENSDART00000185871
pias2
protein inhibitor of activated STAT, 2
chr6_-_18531760 1.13 ENSDART00000167167
utp6
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr24_-_7826489 1.13 ENSDART00000112777
si:dkey-197c15.6
si:dkey-197c15.6
chr15_-_34933560 1.10 ENSDART00000006288
dhx16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr3_+_36617024 1.09 ENSDART00000189957
pdxdc1
pyridoxal-dependent decarboxylase domain containing 1
chr12_+_29240124 1.09 ENSDART00000053761
ENSDART00000130172
bms1
BMS1 ribosome biogenesis factor
chr24_+_31459715 1.09 ENSDART00000181102
ENSDART00000189950
ENSDART00000192321
ENSDART00000126380
cnbd1
cyclic nucleotide binding domain containing 1
chr15_-_41311292 1.09 ENSDART00000133835
ENSDART00000085645
ENSDART00000134075
usp16
ubiquitin specific peptidase 16
chr19_+_34230108 1.09 ENSDART00000141950
galnt12
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12
chr15_-_15230264 1.08 ENSDART00000155400
rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr14_-_5407555 1.06 ENSDART00000001424
pcgf1
polycomb group ring finger 1
chr6_-_18531349 1.05 ENSDART00000160693
ENSDART00000169780
utp6
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr13_+_9559461 1.05 ENSDART00000047740
wdr32
WD repeat domain 32
chr23_+_31979602 1.05 ENSDART00000140351
pan2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr20_-_1268863 1.04 ENSDART00000109321
ENSDART00000027119
lats1
large tumor suppressor kinase 1
chr24_+_15020402 1.04 ENSDART00000148102
dok6
docking protein 6
chr15_-_43284021 1.03 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr18_+_3169579 1.03 ENSDART00000164724
ENSDART00000186340
ENSDART00000181247
ENSDART00000168056
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr19_-_34742440 1.02 ENSDART00000122625
ENSDART00000175621
elp2
elongator acetyltransferase complex subunit 2
chr22_-_10752471 1.02 ENSDART00000081191
sass6
SAS-6 centriolar assembly protein
chr5_+_47863153 1.02 ENSDART00000051518
rasa1a
RAS p21 protein activator (GTPase activating protein) 1a
chr13_-_44782462 1.02 ENSDART00000141298
ENSDART00000099990
btbd9
BTB (POZ) domain containing 9
chr19_+_37118547 1.02 ENSDART00000103163
cx30.9
connexin 30.9
chr7_-_28058442 1.02 ENSDART00000173842
si:ch211-235p24.2
si:ch211-235p24.2
chr1_-_28950366 1.01 ENSDART00000110270
pwp2h
PWP2 periodic tryptophan protein homolog (yeast)
chr5_+_25084385 1.01 ENSDART00000134526
ENSDART00000111863
paxx
PAXX, non-homologous end joining factor
chr16_-_44673851 1.01 ENSDART00000015139
dcaf13
ddb1 and cul4 associated factor 13
chr21_+_38033226 0.98 ENSDART00000085728
klf8
Kruppel-like factor 8
chr15_+_19884242 0.98 ENSDART00000154437
ENSDART00000054416
dyrk1ab
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b
chr17_+_37253706 0.97 ENSDART00000076004
tmem62
transmembrane protein 62
chr15_+_17100697 0.97 ENSDART00000183565
ENSDART00000123197
relb
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr4_+_12292274 0.96 ENSDART00000061070
ENSDART00000150786
mkrn1
makorin, ring finger protein, 1
chr14_-_45558490 0.95 ENSDART00000165060
ints5
integrator complex subunit 5
chr8_+_47683539 0.93 ENSDART00000190701
dpp9
dipeptidyl-peptidase 9
chr6_-_54444929 0.92 ENSDART00000154121
sys1
Sys1 golgi trafficking protein
chr6_-_54433995 0.92 ENSDART00000017230
snrpc
small nuclear ribonucleoprotein polypeptide C
chr13_-_33700461 0.91 ENSDART00000160520
mad2l1bp
MAD2L1 binding protein
chr9_-_41090048 0.90 ENSDART00000131681
ENSDART00000182552
asnsd1
asparagine synthetase domain containing 1
chr6_+_3334710 0.90 ENSDART00000132848
st3gal3a
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr1_+_41596099 0.90 ENSDART00000111367
si:dkey-56e3.3
si:dkey-56e3.3
chr12_-_14211293 0.90 ENSDART00000158399
avl9
AVL9 homolog (S. cerevisiase)
chr3_-_27066451 0.90 ENSDART00000156228
ENSDART00000156311
atf7ip2
activating transcription factor 7 interacting protein 2
chr8_-_19246342 0.89 ENSDART00000147172
abhd17ab
abhydrolase domain containing 17Ab
chr20_+_29587995 0.89 ENSDART00000153339
adam17b
ADAM metallopeptidase domain 17b
chr7_+_35193832 0.88 ENSDART00000189002
zdhhc1
zinc finger, DHHC-type containing 1
chr6_-_29159888 0.88 ENSDART00000110288
zbtb11
zinc finger and BTB domain containing 11
chr1_-_44048798 0.87 ENSDART00000073746
si:ch73-109d9.2
si:ch73-109d9.2
chr21_+_38745094 0.87 ENSDART00000113316
heatr6
HEAT repeat containing 6
chr11_+_24348425 0.86 ENSDART00000089747
nfs1
NFS1 cysteine desulfurase
chr14_-_23684814 0.85 ENSDART00000024604
mars2
methionyl-tRNA synthetase 2, mitochondrial
chr13_-_42673978 0.85 ENSDART00000133848
ENSDART00000099738
ENSDART00000099729
ENSDART00000169083
lrrfip2
leucine rich repeat (in FLII) interacting protein 2
chr21_-_11655010 0.85 ENSDART00000144370
ENSDART00000139814
ENSDART00000139289
cast
calpastatin
chr16_+_38337783 0.84 ENSDART00000135008
gabpb2b
GA binding protein transcription factor, beta subunit 2b
chr6_-_34860574 0.84 ENSDART00000073957
slc35d1a
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1a
chr9_+_25853052 0.84 ENSDART00000127135
gtdc1
glycosyltransferase-like domain containing 1
chr9_-_24218367 0.84 ENSDART00000135356
nabp1a
nucleic acid binding protein 1a
chr15_+_46313082 0.83 ENSDART00000153830
si:ch1073-190k2.1
si:ch1073-190k2.1
chr5_+_28497956 0.82 ENSDART00000191935
nfr
notochord formation related
chr20_-_23946296 0.80 ENSDART00000143005
mdn1
midasin AAA ATPase 1
chr15_-_766015 0.79 ENSDART00000190648
si:dkey-7i4.15
si:dkey-7i4.15
chr14_-_5407118 0.79 ENSDART00000168074
pcgf1
polycomb group ring finger 1
chr18_-_3552414 0.79 ENSDART00000163762
ENSDART00000165434
ENSDART00000161197
ENSDART00000166841
ENSDART00000170260
dcun1d5
DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
chr21_-_14762944 0.79 ENSDART00000114096
arrdc1b
arrestin domain containing 1b
chr21_-_40938382 0.79 ENSDART00000008593
yipf5
Yip1 domain family, member 5
chr23_+_4260458 0.79 ENSDART00000103747
srsf6a
serine/arginine-rich splicing factor 6a
chr24_+_17069420 0.79 ENSDART00000014787
pip4k2aa
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a
chr3_-_36419641 0.78 ENSDART00000173545
cog1
component of oligomeric golgi complex 1
chr17_-_31579715 0.78 ENSDART00000110167
ENSDART00000191092
rpap1
RNA polymerase II associated protein 1
chr13_+_14006118 0.76 ENSDART00000131875
ENSDART00000089528
atrn
attractin
chr2_+_3044992 0.76 ENSDART00000020463
zgc:63882
zgc:63882
chr5_-_35456269 0.76 ENSDART00000051312
ttc33
tetratricopeptide repeat domain 33
chr12_-_31724198 0.76 ENSDART00000153056
ENSDART00000165299
ENSDART00000137464
ENSDART00000080173
srsf2a
serine/arginine-rich splicing factor 2a
chr7_-_29356084 0.75 ENSDART00000075757
gtf2a2
general transcription factor IIA, 2
chr24_-_13349802 0.75 ENSDART00000164729
terf1
telomeric repeat binding factor (NIMA-interacting) 1
chr3_+_59880317 0.75 ENSDART00000166922
ENSDART00000108647
alyref
Aly/REF export factor
chr13_-_18069421 0.74 ENSDART00000146772
ENSDART00000134477
zfand4
zinc finger, AN1-type domain 4
chr19_+_19241372 0.74 ENSDART00000184392
ENSDART00000165008
ptpn23b
protein tyrosine phosphatase, non-receptor type 23, b
chr15_-_6650993 0.74 ENSDART00000002922
atm
ATM serine/threonine kinase
chr8_-_1267247 0.73 ENSDART00000150064
cdc14b
cell division cycle 14B
chr15_-_25365319 0.73 ENSDART00000152651
cluha
clustered mitochondria (cluA/CLU1) homolog a
chr18_-_18584839 0.73 ENSDART00000159274
sf3b3
splicing factor 3b, subunit 3
chr19_-_32042105 0.72 ENSDART00000088358
znf704
zinc finger protein 704
chr14_+_16151636 0.72 ENSDART00000159352
polr1a
polymerase (RNA) I polypeptide A
chr8_+_39770162 0.72 ENSDART00000190677
hps4
Hermansky-Pudlak syndrome 4
chr20_-_33174899 0.70 ENSDART00000047834
nbas
neuroblastoma amplified sequence
chr11_+_25693395 0.70 ENSDART00000110224
mon1bb
MON1 secretory trafficking family member Bb
chr24_-_41195068 0.70 ENSDART00000121592
acvr2ba
activin A receptor type 2Ba
chr24_+_19522094 0.69 ENSDART00000191042
ENSDART00000184714
ENSDART00000180782
sulf1
sulfatase 1
chr11_-_16115804 0.68 ENSDART00000143436
ENSDART00000157928
rpf1
ribosome production factor 1 homolog
chr9_+_12905591 0.68 ENSDART00000139377
si:dkey-230p4.1
si:dkey-230p4.1
chr1_+_58990121 0.68 ENSDART00000171654
CABZ01083166.1

chr16_-_17345377 0.67 ENSDART00000143056
zyx
zyxin
chr2_-_51741711 0.67 ENSDART00000171301
si:ch211-9d9.1
si:ch211-9d9.1
chr11_+_44236183 0.67 ENSDART00000193470
gnb4b
guanine nucleotide binding protein (G protein), beta polypeptide 4b
chr11_-_28050559 0.67 ENSDART00000136859
ece1
endothelin converting enzyme 1
chr3_-_30152836 0.67 ENSDART00000165920
nucb1
nucleobindin 1
chr3_-_30153242 0.67 ENSDART00000077089
nucb1
nucleobindin 1
chr21_+_27302752 0.65 ENSDART00000012855
sart1
SART1, U4/U6.U5 tri-snRNP-associated protein 1
chr13_-_12494575 0.65 ENSDART00000137761
si:dkey-20i10.7
si:dkey-20i10.7
chr3_-_27065477 0.64 ENSDART00000185660
atf7ip2
activating transcription factor 7 interacting protein 2
chr15_-_25365570 0.64 ENSDART00000152754
cluha
clustered mitochondria (cluA/CLU1) homolog a
chr8_-_4031121 0.63 ENSDART00000169474
ENSDART00000163754
mtmr3
myotubularin related protein 3
chr6_+_41808673 0.62 ENSDART00000038163
rad18
RAD18 E3 ubiquitin protein ligase
chr7_-_66693712 0.62 ENSDART00000021317
ctr9
CTR9 homolog, Paf1/RNA polymerase II complex component
chr5_-_13086616 0.62 ENSDART00000051664
ypel1
yippee-like 1
chr15_+_17100412 0.62 ENSDART00000154418
relb
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr6_+_37625787 0.61 ENSDART00000065122
tubgcp5
tubulin, gamma complex associated protein 5
chr7_-_50349430 0.61 ENSDART00000065864
ttc17
tetratricopeptide repeat domain 17
chr15_-_2519640 0.61 ENSDART00000047013
srprb
signal recognition particle receptor, B subunit
chr8_-_1266181 0.60 ENSDART00000148654
ENSDART00000149924
cdc14b
cell division cycle 14B
chr1_+_47165842 0.60 ENSDART00000053152
ENSDART00000167051
cbr1
carbonyl reductase 1
chr7_+_38809241 0.60 ENSDART00000190979
harbi1
harbinger transposase derived 1
chr3_-_34528306 0.60 ENSDART00000023039
sept9a
septin 9a
chr25_-_24248000 0.60 ENSDART00000073527
spty2d1
SPT2 chromatin protein domain containing 1
chr5_+_29715040 0.60 ENSDART00000192563
ddx31
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr7_-_13906409 0.59 ENSDART00000062257
slc39a1
solute carrier family 39 (zinc transporter), member 1
chr24_-_13349464 0.59 ENSDART00000134482
ENSDART00000139212
terf1
telomeric repeat binding factor (NIMA-interacting) 1
chr4_-_22749553 0.59 ENSDART00000040033
nup107
nucleoporin 107
chr2_+_16798652 0.59 ENSDART00000145778
ENSDART00000087120
eif4g1a
eukaryotic translation initiation factor 4 gamma, 1a
chr4_-_20108833 0.59 ENSDART00000100867
fam3c
family with sequence similarity 3, member C
chr16_-_6944927 0.59 ENSDART00000149620
pmvk
phosphomevalonate kinase
chr17_+_33375469 0.59 ENSDART00000032827
zgc:162964
zgc:162964
chr2_+_49457626 0.59 ENSDART00000129967
sh3gl1a
SH3-domain GRB2-like 1a
chr17_+_24684778 0.58 ENSDART00000146309
ENSDART00000082237
znf593
zinc finger protein 593
chr1_+_46598764 0.58 ENSDART00000053240
cab39l
calcium binding protein 39-like
chr5_-_32489796 0.57 ENSDART00000168870
gpr107
G protein-coupled receptor 107
chr14_-_10617923 0.57 ENSDART00000133723
ENSDART00000131939
ENSDART00000136649
si:dkey-92i17.2
si:dkey-92i17.2
chr16_+_33931032 0.57 ENSDART00000167240
snip1
Smad nuclear interacting protein
chr2_+_4383061 0.57 ENSDART00000163986
wacb
WW domain containing adaptor with coiled-coil b
chr20_+_715739 0.57 ENSDART00000136768
myo6a
myosin VIa
chr3_-_34136368 0.56 ENSDART00000136900
ENSDART00000186125
clpp
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr17_+_27456804 0.56 ENSDART00000017756
ENSDART00000181461
ENSDART00000180178
ctsl.1
cathepsin L.1
chr2_+_49457449 0.55 ENSDART00000185470
sh3gl1a
SH3-domain GRB2-like 1a
chr2_-_45510699 0.55 ENSDART00000024034
ENSDART00000145634
gpsm2
G protein signaling modulator 2
chr15_-_34668485 0.55 ENSDART00000186605
bag6
BCL2 associated athanogene 6
chr14_+_712115 0.55 ENSDART00000157494
ENSDART00000166516
ENSDART00000082017
ENSDART00000122374
ENSDART00000170203
ints10
integrator complex subunit 10
chr2_+_46032678 0.54 ENSDART00000184382
ENSDART00000125971
gpc1b
glypican 1b
chr14_-_43616572 0.54 ENSDART00000111189
gar1
GAR1 homolog, ribonucleoprotein
chr15_-_14642186 0.53 ENSDART00000164166
si:dkey-260j18.2
si:dkey-260j18.2
chr9_-_52490579 0.52 ENSDART00000161667
smarcal1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr24_-_26369185 0.52 ENSDART00000080039
lrrc31
leucine rich repeat containing 31
chr6_+_12482599 0.52 ENSDART00000090316
stk24b
serine/threonine kinase 24b (STE20 homolog, yeast)
chr9_-_28255029 0.51 ENSDART00000160387
ccnyl1
cyclin Y-like 1
chr2_-_45510223 0.51 ENSDART00000113058
gpsm2
G protein signaling modulator 2
chr7_-_34062301 0.51 ENSDART00000052404
map2k5
mitogen-activated protein kinase kinase 5
chr5_+_44806374 0.50 ENSDART00000184237
ctsla
cathepsin La

Network of associatons between targets according to the STRING database.

First level regulatory network of SPDEF

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.8 GO:0042779 tRNA 3'-trailer cleavage(GO:0042779)
0.8 3.8 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.4 1.3 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.4 1.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.3 1.0 GO:0008344 adult locomotory behavior(GO:0008344)
0.3 1.3 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.3 1.0 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.3 1.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 1.4 GO:0072425 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.2 0.6 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.2 0.6 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.2 1.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.2 0.7 GO:1903232 melanosome assembly(GO:1903232)
0.2 0.7 GO:2000623 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 2.9 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747) regulation of clathrin-mediated endocytosis(GO:2000369)
0.2 1.0 GO:0003232 bulbus arteriosus development(GO:0003232)
0.2 5.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.2 1.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2 0.9 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.6 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 1.0 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.4 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 1.3 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 1.9 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.4 GO:1990120 messenger ribonucleoprotein complex assembly(GO:1990120)
0.1 0.8 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.5 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.1 0.7 GO:0016572 histone phosphorylation(GO:0016572)
0.1 0.8 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 1.5 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.9 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 2.8 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 1.7 GO:1900153 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1 1.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.0 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 1.2 GO:0046620 regulation of organ growth(GO:0046620)
0.1 0.5 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.6 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 2.3 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 1.0 GO:0021681 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.8 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 0.4 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.7 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 0.5 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.5 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529)
0.1 0.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 0.6 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 3.4 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.1 0.9 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 1.9 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.9 GO:0045116 protein neddylation(GO:0045116)
0.1 0.6 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 1.3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.1 2.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 1.6 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.1 1.5 GO:0016180 snRNA processing(GO:0016180)
0.1 1.1 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.1 0.7 GO:0009303 rRNA transcription(GO:0009303)
0.1 5.4 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.9 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.5 GO:0016074 snoRNA metabolic process(GO:0016074)
0.0 0.5 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.0 0.9 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.8 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.0 0.4 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.2 GO:2000058 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.0 0.2 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.7 GO:0016486 peptide hormone processing(GO:0016486)
0.0 1.0 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 1.8 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.6 GO:0031060 regulation of histone methylation(GO:0031060)
0.0 0.5 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.4 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 1.3 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 1.1 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.8 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.8 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.9 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.1 GO:0015824 L-alanine transport(GO:0015808) proline transport(GO:0015824)
0.0 1.0 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.6 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.7 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.2 GO:0003190 heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190)
0.0 1.1 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 1.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.6 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.6 GO:0046660 female sex differentiation(GO:0046660)
0.0 0.4 GO:0051382 kinetochore assembly(GO:0051382)
0.0 1.1 GO:0046466 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.0 1.1 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 0.6 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.7 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.2 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 0.3 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.6 GO:0072599 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.8 GO:0048634 regulation of muscle organ development(GO:0048634)
0.0 0.3 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.4 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.0 0.5 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 1.0 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.3 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.0 0.7 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 0.3 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.2 GO:0016233 telomere capping(GO:0016233)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.0 0.7 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800) positive regulation of proteolysis involved in cellular protein catabolic process(GO:1903052) positive regulation of cellular protein catabolic process(GO:1903364)
0.0 0.6 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.3 GO:0043489 RNA stabilization(GO:0043489)
0.0 0.8 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.4 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.5 GO:0000187 activation of MAPK activity(GO:0000187)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.5 3.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.3 1.0 GO:0031251 PAN complex(GO:0031251)
0.3 1.0 GO:0098536 deuterosome(GO:0098536)
0.3 1.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 3.4 GO:0048179 activin receptor complex(GO:0048179)
0.2 1.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 0.8 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.2 0.7 GO:0031085 BLOC-3 complex(GO:0031085)
0.2 1.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 0.6 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.8 GO:0070876 SOSS complex(GO:0070876)
0.1 0.4 GO:0042382 paraspeckles(GO:0042382)
0.1 1.0 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 1.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.5 GO:0000243 commitment complex(GO:0000243)
0.1 1.0 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 2.9 GO:0032040 small-subunit processome(GO:0032040)
0.1 2.0 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.1 1.1 GO:0030686 90S preribosome(GO:0030686)
0.1 0.7 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.1 0.6 GO:0071818 BAT3 complex(GO:0071818)
0.1 1.9 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.1 1.5 GO:0032039 integrator complex(GO:0032039)
0.1 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.2 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.2 GO:0043291 RAVE complex(GO:0043291)
0.1 0.8 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.4 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 1.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.5 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0016586 RSC complex(GO:0016586)
0.0 1.1 GO:0055037 recycling endosome(GO:0055037)
0.0 1.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 2.8 GO:0010008 endosome membrane(GO:0010008)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.6 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.3 GO:0000922 spindle pole(GO:0000922)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.7 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.1 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 2.8 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.8 3.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.4 1.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.3 2.4 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.3 1.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.3 1.3 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.3 1.1 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.3 1.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 2.9 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 1.3 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 3.4 GO:0017002 activin-activated receptor activity(GO:0017002)
0.2 1.0 GO:0030620 U2 snRNA binding(GO:0030620)
0.2 0.8 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2 0.5 GO:0036310 annealing helicase activity(GO:0036310)
0.2 0.8 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.2 0.9 GO:0030619 U1 snRNA binding(GO:0030619)
0.2 1.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 2.0 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.5 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.8 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.6 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.4 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 0.3 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.1 0.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.5 GO:0032183 SUMO binding(GO:0032183)
0.1 0.3 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 1.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.4 GO:0008430 selenium binding(GO:0008430)
0.1 1.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.7 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.2 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.1 1.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 2.8 GO:0030145 manganese ion binding(GO:0030145)
0.1 0.5 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 1.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.9 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 1.1 GO:0045159 myosin II binding(GO:0045159)
0.1 0.5 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.6 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.2 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.5 GO:0051219 protein phosphorylated amino acid binding(GO:0045309) phosphoprotein binding(GO:0051219)
0.1 0.2 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.1 1.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.4 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 2.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.3 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.7 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 5.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.9 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 3.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.9 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.5 GO:0031386 protein tag(GO:0031386)
0.0 1.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.5 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.7 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.5 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.2 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 2.1 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.3 GO:0043142 DNA clamp loader activity(GO:0003689) single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) protein-DNA loading ATPase activity(GO:0033170) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.1 GO:0005463 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.0 3.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.5 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 1.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.4 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 4.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 1.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 1.0 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 2.0 PID BARD1 PATHWAY BARD1 signaling events
0.1 2.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.6 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.3 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 2.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.7 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.5 PID ATR PATHWAY ATR signaling pathway
0.0 1.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 1.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.0 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.8 REACTOME KINESINS Genes involved in Kinesins
0.1 3.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 0.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 0.5 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.1 0.6 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.4 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.9 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.8 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.1 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 0.1 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.6 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.2 REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX Genes involved in Formation of RNA Pol II elongation complex
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation