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PRJNA195909:zebrafish embryo and larva development

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Results for atf1

Z-value: 1.52

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Transcription factors associated with atf1

Gene Symbol Gene ID Gene Info
ENSDARG00000044301 activating transcription factor 1
ENSDARG00000109865 activating transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
atf1dr11_v1_chr6_-_39521832_395218320.781.4e-02Click!

Activity profile of atf1 motif

Sorted Z-values of atf1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_34915886 2.19 ENSDART00000141201
ENSDART00000002166
cyclin A1
chr16_-_42066523 2.07 ENSDART00000180538
ENSDART00000058620
zona pellucida glycoprotein 3d tandem duplicate 1
chr16_-_29387215 1.83 ENSDART00000148787
S100 calcium binding protein A1
chr12_-_22238004 1.75 ENSDART00000038310
ORMDL sphingolipid biosynthesis regulator 3
chr19_+_14454306 1.54 ENSDART00000161965
zinc finger, DHHC-type containing 18b
chr7_-_51773166 1.42 ENSDART00000054591
bone morphogenetic protein 15
chr18_+_14633974 1.34 ENSDART00000133834
VPS9 domain containing 1
chr4_-_16628801 1.31 ENSDART00000040708
ENSDART00000064009
caprin family member 2
chr6_+_40992883 1.28 ENSDART00000076061
transforming growth factor, alpha
chr3_-_49504023 1.24 ENSDART00000168108
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
chr12_-_17863467 1.21 ENSDART00000042006
BAI1-associated protein 2-like 1a
chr2_+_35603637 1.20 ENSDART00000147278
polo-like kinase 3 (Drosophila)
chr20_+_39223235 1.18 ENSDART00000132132
RALBP1 associated Eps domain containing 1
chr7_+_46019780 1.17 ENSDART00000163991
cyclin E1
chr8_-_5267442 1.17 ENSDART00000155816
protein phosphatase 2, regulatory subunit B, alpha a
chr20_+_46572550 1.16 ENSDART00000139051
ENSDART00000161320
basic leucine zipper transcription factor, ATF-like
chr6_-_52484566 1.14 ENSDART00000112146
family with sequence similarity 83, member C
chr7_+_34549198 1.11 ENSDART00000173784
formin homology 2 domain containing 1
chr5_-_29531948 1.08 ENSDART00000098360
arrestin domain containing 1a
chr4_-_16124417 1.08 ENSDART00000128079
ENSDART00000077664
ATPase plasma membrane Ca2+ transporting 1a
chr22_+_24623936 1.08 ENSDART00000160924
mucolipin 2
chr15_+_5116179 1.07 ENSDART00000101937
phosphoglucomutase 2-like 1
chr12_-_10512911 1.06 ENSDART00000124562
ENSDART00000106163
zgc:152977
chr22_+_1170294 1.05 ENSDART00000159761
ENSDART00000169809
interferon regulatory factor 6
chr3_-_40933415 1.04 ENSDART00000055201
forkhead box K1
chr10_+_14488625 1.03 ENSDART00000026383
sigma non-opioid intracellular receptor 1
chr7_+_34549377 1.02 ENSDART00000191814
formin homology 2 domain containing 1
chr17_-_7792376 1.00 ENSDART00000064655
zinc finger and BTB domain containing 2a
chr17_+_32623931 1.00 ENSDART00000144217
cathepsin Ba
chr4_-_65037243 0.97 ENSDART00000170059
si:ch211-283l16.1
chr15_-_41689981 0.96 ENSDART00000059327
splA/ryanodine receptor domain and SOCS box containing 4b
chr6_-_54348568 0.95 ENSDART00000156501
zgc:101577
chr16_-_41535690 0.95 ENSDART00000102662
ribonuclease P/MRP 25 subunit-like
chr18_+_17493859 0.95 ENSDART00000090754
si:dkey-102f14.5
chr11_+_36379293 0.94 ENSDART00000135360
ataxin 7-like 2a
chr20_-_36671660 0.93 ENSDART00000134819
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6a
chr10_+_32646402 0.93 ENSDART00000137244
zinc finger and BTB domain containing 21
chr1_-_17693273 0.93 ENSDART00000146258
cilia and flagella associated protein 97
chr19_-_6193448 0.92 ENSDART00000151405
Ets2 repressor factor
chr6_+_40992409 0.92 ENSDART00000151419
transforming growth factor, alpha
chr23_+_19655301 0.91 ENSDART00000104441
ENSDART00000135269
abhydrolase domain containing 6b
chr7_-_19998723 0.90 ENSDART00000173458
thyroid hormone receptor interactor 6
chr23_+_19590006 0.89 ENSDART00000021231
sarcolemma associated protein b
chr11_-_13341483 0.89 ENSDART00000164978
microtubule associated serine/threonine kinase 3b
chr8_+_11687586 0.88 ENSDART00000146241
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr17_-_31212420 0.88 ENSDART00000086511
RNA pseudouridylate synthase domain containing 2
chr25_-_37084032 0.87 ENSDART00000025494
hypoxanthine phosphoribosyltransferase 1, like
chr19_-_6840506 0.86 ENSDART00000081568
transcription factor 19 (SC1), like
chr12_-_24832297 0.86 ENSDART00000066317
forkhead box N2b
chr13_-_27354003 0.86 ENSDART00000101479
ENSDART00000044652
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
chr10_-_6588793 0.85 ENSDART00000163788
chromodomain helicase DNA binding protein 1
chr21_+_3928947 0.85 ENSDART00000149777
senataxin
chr5_+_13472234 0.85 ENSDART00000114069
ENSDART00000132406
cyclin and CBS domain divalent metal cation transport mediator 4b
chr14_-_763744 0.85 ENSDART00000165856
tripartite motif containing 35-27
chr2_+_12255568 0.84 ENSDART00000184164
ENSDART00000013454
phosphoribosyl transferase domain containing 1
chr21_+_17051478 0.84 ENSDART00000047201
ENSDART00000161650
ENSDART00000167298
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr7_-_33868903 0.83 ENSDART00000173500
ENSDART00000178746
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr17_+_52612866 0.83 ENSDART00000182828
ENSDART00000191156
ENSDART00000188814
ENSDART00000109891
angel homolog 1 (Drosophila)
chr2_-_55779927 0.82 ENSDART00000168579

chr13_+_47623916 0.81 ENSDART00000109266
c-mer proto-oncogene tyrosine kinase a
chr23_-_25686894 0.81 ENSDART00000181420
ENSDART00000088208
low density lipoprotein receptor-related protein 1Ab
chr3_+_61221194 0.81 ENSDART00000110030
lemur tyrosine kinase 2
chr23_-_1571682 0.80 ENSDART00000013635
F-box protein 30b
chr6_-_21830405 0.80 ENSDART00000151803
ENSDART00000113497
SET domain containing 5
chr10_+_15603082 0.80 ENSDART00000024450
zinc finger, AN1-type domain 5b
chr8_+_50190742 0.80 ENSDART00000099863
solute carrier family 25 (mitochondrial iron transporter), member 37
chr17_-_2690083 0.79 ENSDART00000135374
protein tyrosine phosphatase, non-receptor type 21
chr21_+_20391978 0.79 ENSDART00000180817
si:dkey-30k6.5
chr8_+_3649036 0.79 ENSDART00000033152
RAB35, member RAS oncogene family b
chr20_+_24448007 0.78 ENSDART00000139866
si:dkey-273g18.1
chr15_-_41689684 0.78 ENSDART00000143447
splA/ryanodine receptor domain and SOCS box containing 4b
chr7_+_69449814 0.78 ENSDART00000109644
CTD nuclear envelope phosphatase 1b
chr23_+_19590598 0.78 ENSDART00000170149
sarcolemma associated protein b
chr3_-_61494840 0.78 ENSDART00000101957
BAI1-associated protein 2-like 1b
chr13_+_534453 0.78 ENSDART00000147909
wu:fc17b08
chr16_+_38240027 0.77 ENSDART00000111081
prune exopolyphosphatase
chr23_-_24226533 0.77 ENSDART00000109134
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr2_-_31800521 0.77 ENSDART00000112763
reticulophagy regulator 1
chr4_-_26035770 0.77 ENSDART00000124514
ubiquitin specific peptidase 44
chr17_+_39741926 0.76 ENSDART00000154996
ENSDART00000154599
si:dkey-229e3.2
chr22_-_36829006 0.75 ENSDART00000170256
ENSDART00000086064
microtubule-associated protein 1Sa
chr21_+_7131970 0.75 ENSDART00000161921
zgc:113019
chr20_-_51831657 0.75 ENSDART00000165076
melanoma inhibitory activity family, member 3
chr7_-_69429561 0.74 ENSDART00000127351
ataxin 1-like
chr5_+_36439405 0.74 ENSDART00000102973
ectodysplasin A
chr13_-_13030851 0.74 ENSDART00000009499
nuclear receptor binding SET domain protein 2
chr25_+_35891342 0.73 ENSDART00000147093
LSM14A mRNA processing body assembly factor a
chr23_+_28718863 0.73 ENSDART00000078156
spermidine synthase
chr21_+_3775551 0.73 ENSDART00000111699
torsin family 1
chr23_-_19051710 0.73 ENSDART00000111852
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr3_+_7771420 0.73 ENSDART00000156809
ENSDART00000156309
hook microtubule-tethering protein 2
chr4_+_73651053 0.73 ENSDART00000150532
ENSDART00000172536
zinc finger protein 989
chr9_+_34148714 0.73 ENSDART00000078051
G protein-coupled receptor 161
chr22_+_12162470 0.71 ENSDART00000053045
ENSDART00000143599
cyclin T2b
chr2_+_41524238 0.71 ENSDART00000122860
ENSDART00000017977
activin A receptor, type 1 like
chr25_+_34845115 0.71 ENSDART00000061996
transmembrane protein 231
chr12_+_33894396 0.71 ENSDART00000130853
ENSDART00000152988
major facilitator superfamily domain containing 13A
chr22_+_38935060 0.71 ENSDART00000183732
ENSDART00000130055
sirtuin 7
chr23_+_45845159 0.70 ENSDART00000023944
lamin L3
chr4_+_63790028 0.70 ENSDART00000160964
si:dkey-92j16.2
chr7_-_69352424 0.70 ENSDART00000170714
adaptor-related protein complex 1, gamma 1 subunit
chr11_+_44503774 0.70 ENSDART00000169295
endoplasmic reticulum oxidoreductase beta
chr11_+_42765963 0.70 ENSDART00000156080
ENSDART00000179888
tudor domain containing 3
chr2_+_5843694 0.69 ENSDART00000182364
DIS3 like 3'-5' exoribonuclease 2
chr24_-_19718077 0.69 ENSDART00000109107
ENSDART00000056082
cysteine-serine-rich nuclear protein 1b
chr6_-_6673813 0.69 ENSDART00000150995
si:dkey-261j15.2
chr18_-_22094102 0.69 ENSDART00000100904
par-6 family cell polarity regulator alpha
chr14_+_30285613 0.69 ENSDART00000173090
microtubule associated tumor suppressor 1a
chr12_+_33320504 0.69 ENSDART00000021491
casein kinase 1, delta b
chr25_-_35102781 0.69 ENSDART00000180881
ENSDART00000153747
si:dkey-108k21.24
chr16_-_44673851 0.69 ENSDART00000015139
ddb1 and cul4 associated factor 13
chr9_+_22632126 0.68 ENSDART00000139434
ets variant 5a
chr1_-_40411944 0.68 ENSDART00000144135
mastermind-like transcriptional coactivator 3
chr1_-_55068941 0.68 ENSDART00000152143
ENSDART00000152590
pellino E3 ubiquitin protein ligase 1a
chr8_+_48965767 0.67 ENSDART00000008058
AP2 associated kinase 1a
chr7_+_66634167 0.67 ENSDART00000027616
eukaryotic translation initiation factor 4, gamma 2a
chr18_+_18879733 0.67 ENSDART00000019581
ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)
chr15_-_1843831 0.67 ENSDART00000156718
ENSDART00000154175
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr4_-_73394385 0.67 ENSDART00000174205
ENSDART00000143417
zgc:162958
chr25_-_6447835 0.67 ENSDART00000012820
snurportin 1
chr23_-_19051869 0.67 ENSDART00000140866
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr17_+_25187226 0.66 ENSDART00000148431
CLN8, transmembrane ER and ERGIC protein
chr10_-_28380919 0.65 ENSDART00000183409
ENSDART00000183105
ENSDART00000100207
ENSDART00000185392
ENSDART00000131220
B-cell translocation gene 3
chr9_-_27749936 0.65 ENSDART00000064156
TBCC domain containing 1
chr22_+_35089031 0.65 ENSDART00000076040
serum response factor a
chr13_+_33368503 0.65 ENSDART00000139650
BRF1, RNA polymerase III transcription initiation factor a
chr9_-_41507712 0.65 ENSDART00000135821
major facilitator superfamily domain containing 6b
chr9_-_28939181 0.64 ENSDART00000101276
ENSDART00000135334
erythrocyte membrane protein band 4.1 like 5
chr9_+_22631672 0.64 ENSDART00000101770
ENSDART00000126015
ENSDART00000145005
ets variant 5a
chr19_-_46058963 0.64 ENSDART00000170409
nucleoporin 153
chr3_+_32933663 0.64 ENSDART00000112742
neighbor of brca1 gene 1b
chr8_+_29742237 0.64 ENSDART00000133955
ENSDART00000020621
mitogen-activated protein kinase 4
chr18_+_20482369 0.63 ENSDART00000100668
kelch repeat and BTB (POZ) domain containing 4
chr17_-_5610514 0.63 ENSDART00000004043
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr14_+_31618982 0.63 ENSDART00000026195
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6a
chr2_+_32743807 0.63 ENSDART00000022909
kelch-like family member 18
chr14_-_41468892 0.62 ENSDART00000173099
ENSDART00000003170
MID1 interacting protein 1, like
chr5_-_28016805 0.62 ENSDART00000078642
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr12_+_46543572 0.62 ENSDART00000167510
HID1 domain containing b
chr5_-_68782641 0.62 ENSDART00000141699
methylphosphate capping enzyme
chr14_-_52433292 0.62 ENSDART00000164272
RE1-silencing transcription factor
chr10_+_44373349 0.61 ENSDART00000172191
small nuclear ribonucleoprotein 35 (U11/U12)
chr21_-_14878220 0.61 ENSDART00000131237
unc-51 like autophagy activating kinase 1
chr11_+_2710530 0.61 ENSDART00000132768
ENSDART00000030921
ENSDART00000040147
mitogen-activated protein kinase 14b
chr13_+_8840772 0.61 ENSDART00000059321
epithelial cell adhesion molecule
chr8_+_44714336 0.61 ENSDART00000145801
ELMO/CED-12 domain containing 3
chr7_-_19999152 0.61 ENSDART00000173881
ENSDART00000100798
thyroid hormone receptor interactor 6
chr22_+_3184500 0.60 ENSDART00000176409
ENSDART00000160604
FtsJ RNA methyltransferase homolog 3
chr13_+_46941930 0.60 ENSDART00000056962
F-box protein 5
chr20_-_51831816 0.60 ENSDART00000060505
melanoma inhibitory activity family, member 3
chr10_+_16165533 0.60 ENSDART00000065045
proline-rich coiled-coil 1
chr23_-_29878643 0.60 ENSDART00000058407
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr20_-_37933237 0.60 ENSDART00000142567
ENSDART00000036371
ENSDART00000061445
angel homolog 2 (Drosophila)
chr7_+_1579236 0.60 ENSDART00000172830
SPT16 homolog, facilitates chromatin remodeling subunit
chr3_+_1211242 0.60 ENSDART00000171287
ENSDART00000165769
polymerase (DNA-directed), delta interacting protein 3
chr1_-_20068155 0.60 ENSDART00000102993
methyltransferase like 14
chr7_+_10562118 0.60 ENSDART00000185188
ENSDART00000168801
zinc finger, AN1-type domain 6
chr2_-_43739740 0.60 ENSDART00000113849
kinesin family member 5B, a
chr19_+_46113828 0.60 ENSDART00000159331
ENSDART00000161826
RNA binding motif protein 24a
chr23_+_34990693 0.59 ENSDART00000013449
si:ch211-236h17.3
chr16_+_48460873 0.59 ENSDART00000159902
exostosin glycosyltransferase 1a
chr15_-_23443588 0.59 ENSDART00000170427
ubiquitination factor E4A (UFD2 homolog, yeast)
chr5_+_1965296 0.58 ENSDART00000156224
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr17_+_28005763 0.58 ENSDART00000155838
leucine zipper protein 1
chr4_-_65036768 0.58 ENSDART00000184455
si:ch211-283l16.1
chr18_+_660578 0.58 ENSDART00000161203
si:dkey-205h23.2
chr23_-_44723102 0.57 ENSDART00000129138
monoacylglycerol O-acyltransferase 3a
chr4_-_55040507 0.57 ENSDART00000161731
si:dkey-56m15.3
chr16_-_21915223 0.57 ENSDART00000170634
SET domain, bifurcated 1b
chr11_-_21218172 0.57 ENSDART00000027532
mitogen-activated protein kinase-activated protein kinase 2a
chr24_+_39656834 0.57 ENSDART00000133942
ENSDART00000148089
ENSDART00000145075
STIP1 homology and U-Box containing protein 1
chr13_+_4505079 0.56 ENSDART00000144312
phosphodiesterase 10A
chr24_-_16979728 0.56 ENSDART00000005331
kelch-like family member 15
chr18_+_6558146 0.56 ENSDART00000169401
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr18_+_8917766 0.56 ENSDART00000145226
si:ch211-233h19.2
chr23_+_17509794 0.56 ENSDART00000148457
GID complex subunit 8 homolog b (S. cerevisiae)
chr5_-_9540641 0.56 ENSDART00000124384
ENSDART00000160079
cyclin G associated kinase
chr19_+_13994563 0.56 ENSDART00000164696
transmembrane protein 222b
chr11_+_11120532 0.56 ENSDART00000026135
ENSDART00000189872
lymphocyte antigen 75
chr9_-_27396404 0.56 ENSDART00000136412
ENSDART00000101401
testis expressed 30
chr5_-_24231139 0.55 ENSDART00000143492
SUMO1/sentrin/SMT3 specific peptidase 3a
chr20_-_51559419 0.55 ENSDART00000065231
dispatched homolog 1 (Drosophila)
chr8_-_11004726 0.55 ENSDART00000192594
ENSDART00000020116
tripartite motif containing 33
chr2_-_43739559 0.55 ENSDART00000138947
kinesin family member 5B, a
chr15_-_43995028 0.55 ENSDART00000172485
ENSDART00000186320
NLR family, CARD domain containing 3-like
chr11_-_27827442 0.55 ENSDART00000121847
ENSDART00000132018
ENSDART00000145744
ENSDART00000134677
ENSDART00000130800
cleavage stimulation factor, 3' pre-RNA, subunit 1
chr20_+_2642855 0.55 ENSDART00000058775
zgc:101562
chr6_-_39006449 0.55 ENSDART00000150885
vitamin D receptor b
chr25_-_37186894 0.54 ENSDART00000191647
ENSDART00000182095
tudor domain containing 12
chr6_-_25163722 0.54 ENSDART00000192225
zinc finger protein 326
chr14_-_41308561 0.54 ENSDART00000138232
ADP-ribosylation factor-like 13A
chr7_-_46019756 0.54 ENSDART00000162583
zgc:162297
chr5_+_29831235 0.54 ENSDART00000109660
F11 receptor, tandem duplicate 1
chr24_+_39211288 0.54 ENSDART00000061540
im:7160594
chr19_-_3821678 0.54 ENSDART00000169639
si:dkey-206d17.12
chr22_+_2648931 0.53 ENSDART00000106357
zgc:110821
chr23_-_24542952 0.53 ENSDART00000088777
ATPase 13A2
chr15_+_34963316 0.53 ENSDART00000153840
si:ch73-95l15.5
chr17_-_5732299 0.53 ENSDART00000017244
XK, Kell blood group complex subunit-related family, member 6a
chr2_-_57941037 0.53 ENSDART00000131420
si:dkeyp-68b7.5

Network of associatons between targets according to the STRING database.

First level regulatory network of atf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 0.6 GO:1903430 negative regulation of cell maturation(GO:1903430)
0.4 1.8 GO:0090153 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.4 1.3 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.4 0.4 GO:0016584 nucleosome positioning(GO:0016584)
0.4 1.2 GO:0042832 response to protozoan(GO:0001562) defense response to protozoan(GO:0042832)
0.4 1.1 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.4 1.4 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.3 1.4 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.3 1.2 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.3 0.9 GO:0046099 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.3 1.1 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.3 1.1 GO:0006404 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.3 0.8 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.3 0.8 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.3 2.3 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.2 0.7 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.2 1.0 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.2 0.9 GO:0051182 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.2 0.7 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.2 2.0 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.2 1.1 GO:0034505 tooth mineralization(GO:0034505)
0.2 0.6 GO:1904869 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.2 1.0 GO:0060019 radial glial cell differentiation(GO:0060019)
0.2 0.4 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.2 1.5 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.2 1.1 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.2 0.5 GO:0009193 ribonucleoside diphosphate catabolic process(GO:0009191) pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.2 0.5 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.2 0.5 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.2 1.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 0.7 GO:0051661 Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.2 0.6 GO:0042590 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.2 1.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 0.8 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.2 0.8 GO:0010867 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.2 1.7 GO:0070932 histone H3 deacetylation(GO:0070932)
0.2 0.8 GO:0098535 de novo centriole assembly(GO:0098535)
0.2 0.5 GO:0060571 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.1 0.4 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.1 0.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.4 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 0.6 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.4 GO:0043525 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.1 0.4 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.4 GO:1901994 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.1 0.7 GO:0010586 miRNA metabolic process(GO:0010586)
0.1 0.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.7 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.4 GO:1903504 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.5 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 0.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 1.4 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 2.1 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.8 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 0.4 GO:0033212 iron assimilation(GO:0033212)
0.1 0.9 GO:0014004 microglia differentiation(GO:0014004)
0.1 0.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.3 GO:0031645 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.1 3.0 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 0.2 GO:0051030 snRNA transport(GO:0051030)
0.1 1.1 GO:0061709 reticulophagy(GO:0061709)
0.1 0.6 GO:0072319 clathrin coat disassembly(GO:0072318) vesicle uncoating(GO:0072319)
0.1 1.8 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.5 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.1 0.3 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.8 GO:1903729 regulation of plasma membrane organization(GO:1903729)
0.1 1.0 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.6 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.5 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 0.5 GO:0042766 nucleosome mobilization(GO:0042766)
0.1 2.1 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.7 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.5 GO:0072575 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.1 0.3 GO:2000376 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.1 0.6 GO:0030194 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 0.5 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.1 0.6 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.5 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 1.4 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 0.5 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.4 GO:0048730 epidermis morphogenesis(GO:0048730)
0.1 0.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.8 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 0.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.8 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.2 GO:0070589 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.1 0.6 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 1.3 GO:0035459 cargo loading into vesicle(GO:0035459)
0.1 0.4 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.4 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 0.3 GO:0080009 mRNA methylation(GO:0080009)
0.1 0.2 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 1.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.4 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.1 1.7 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.1 0.3 GO:0071926 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.1 0.5 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.1 GO:0044819 mitotic G1/S transition checkpoint(GO:0044819)
0.1 0.3 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.1 0.8 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 0.6 GO:0048569 post-embryonic organ development(GO:0048569)
0.1 0.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 1.5 GO:0010737 protein kinase A signaling(GO:0010737)
0.1 0.5 GO:0021588 cerebellum formation(GO:0021588)
0.1 0.3 GO:0046324 regulation of glucose import(GO:0046324)
0.1 0.2 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.1 0.3 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.4 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 0.4 GO:0031112 positive regulation of microtubule polymerization or depolymerization(GO:0031112) positive regulation of microtubule polymerization(GO:0031116)
0.1 0.3 GO:0071788 endoplasmic reticulum tubular network maintenance(GO:0071788)
0.1 0.4 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 1.5 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 0.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.2 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.1 0.7 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.1 0.6 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.9 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.1 0.2 GO:1903441 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.1 0.2 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.3 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 0.4 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.3 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.1 1.3 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.1 1.8 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 2.7 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1 0.6 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.2 GO:0010712 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.8 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.7 GO:2000542 negative regulation of gastrulation(GO:2000542)
0.0 0.1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.2 GO:0048103 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 1.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.4 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.0 0.8 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.6 GO:0042694 muscle cell fate specification(GO:0042694)
0.0 0.4 GO:0007220 Notch receptor processing(GO:0007220) beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.0 0.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.7 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 0.6 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.5 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.5 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.2 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.5 GO:0021707 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.4 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.7 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.1 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.5 GO:0050892 intestinal absorption(GO:0050892)
0.0 1.2 GO:0061136 regulation of proteasomal protein catabolic process(GO:0061136)
0.0 0.3 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.7 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.4 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.8 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 1.8 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.3 GO:0010885 regulation of cholesterol storage(GO:0010885)
0.0 0.8 GO:0006826 iron ion transport(GO:0006826)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.4 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.8 GO:0006298 mismatch repair(GO:0006298)
0.0 0.1 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.0 0.1 GO:0061355 Wnt protein secretion(GO:0061355)
0.0 0.3 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.7 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.5 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.6 GO:0031297 replication fork processing(GO:0031297)
0.0 0.8 GO:0008345 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 0.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.5 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.0 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.3 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.4 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.1 GO:0070734 histone H3-K27 methylation(GO:0070734) base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.0 1.8 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.4 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.2 GO:1990748 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.3 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.4 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.4 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.2 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.2 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.6 GO:0001757 somite specification(GO:0001757)
0.0 0.3 GO:2000780 negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.4 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.8 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.4 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.8 GO:0060349 bone morphogenesis(GO:0060349)
0.0 0.6 GO:0035924 cellular response to vascular endothelial growth factor stimulus(GO:0035924)
0.0 0.2 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.8 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.6 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.1 GO:0034727 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) single-organism membrane invagination(GO:1902534)
0.0 0.7 GO:0060348 bone development(GO:0060348)
0.0 1.6 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 0.2 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.1 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.6 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.0 0.6 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.1 GO:0051103 DNA ligation(GO:0006266) DNA ligation involved in DNA repair(GO:0051103)
0.0 0.6 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.4 GO:0072662 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.1 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.4 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0006531 aspartate metabolic process(GO:0006531)
0.0 0.5 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.0 GO:0030201 heparan sulfate proteoglycan metabolic process(GO:0030201)
0.0 0.7 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.0 GO:0043455 regulation of secondary metabolic process(GO:0043455)
0.0 0.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.0 GO:0010165 response to X-ray(GO:0010165)
0.0 0.3 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.2 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.6 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 0.1 GO:0071025 RNA surveillance(GO:0071025)
0.0 0.3 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 1.2 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.8 GO:0016573 histone acetylation(GO:0016573)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.2 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.7 GO:0007098 centrosome cycle(GO:0007098)
0.0 1.2 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.6 GO:0003146 heart jogging(GO:0003146)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.1 GO:0031573 intra-S DNA damage checkpoint(GO:0031573) cellular response to ionizing radiation(GO:0071479)
0.0 0.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.3 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.1 GO:0070307 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.0 0.3 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0 0.1 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.4 1.8 GO:0035339 SPOTS complex(GO:0035339)
0.3 1.2 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.3 0.8 GO:0098536 deuterosome(GO:0098536)
0.2 1.0 GO:0008537 proteasome activator complex(GO:0008537)
0.2 1.4 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 0.6 GO:1990077 primosome complex(GO:1990077)
0.2 0.8 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.6 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.7 GO:0070724 BMP receptor complex(GO:0070724)
0.1 0.5 GO:0044609 DBIRD complex(GO:0044609)
0.1 0.6 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.1 1.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.2 GO:0035101 FACT complex(GO:0035101)
0.1 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.7 GO:0071818 BAT3 complex(GO:0071818)
0.1 0.7 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.7 GO:0031464 inclusion body(GO:0016234) Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.4 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.3 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 0.7 GO:0000796 condensin complex(GO:0000796)
0.1 1.7 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 0.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.7 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 0.7 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 1.0 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 1.8 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.2 GO:0034518 RNA cap binding complex(GO:0034518)
0.1 1.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.4 GO:0016589 NURF complex(GO:0016589)
0.1 0.6 GO:0089701 U2AF(GO:0089701)
0.1 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.0 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 0.3 GO:0000938 GARP complex(GO:0000938)
0.1 1.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.5 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.7 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.1 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.4 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.7 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 1.3 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.6 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.3 GO:0030130 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.6 GO:0030686 90S preribosome(GO:0030686)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 4.1 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 1.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.2 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.8 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.1 GO:0000922 spindle pole(GO:0000922)
0.0 1.6 GO:0016607 nuclear speck(GO:0016607)
0.0 0.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.9 GO:0016604 nuclear body(GO:0016604)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 3.4 GO:0005730 nucleolus(GO:0005730)
0.0 0.9 GO:0032432 actin filament bundle(GO:0032432)
0.0 1.6 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.5 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.0 GO:0055087 Ski complex(GO:0055087)
0.0 0.2 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.8 GO:0005819 spindle(GO:0005819)
0.0 0.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.5 GO:0005657 replication fork(GO:0005657)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.8 GO:0000123 histone acetyltransferase complex(GO:0000123)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.3 0.9 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.3 0.9 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.3 1.4 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.3 0.8 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 1.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.2 0.9 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 0.7 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.2 0.7 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.2 1.4 GO:0070698 type I activin receptor binding(GO:0070698)
0.2 1.0 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.2 0.6 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.2 0.6 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.2 1.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 0.8 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 1.0 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 0.5 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.1 0.6 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.4 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.1 0.5 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 1.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 1.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822) efflux transmembrane transporter activity(GO:0015562)
0.1 0.5 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.1 0.8 GO:0032052 bile acid binding(GO:0032052)
0.1 0.4 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.1 2.1 GO:0032190 acrosin binding(GO:0032190)
0.1 0.9 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.3 GO:0030623 U5 snRNA binding(GO:0030623)
0.1 0.3 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.1 0.5 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.2 GO:0043495 protein anchor(GO:0043495)
0.1 0.3 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.3 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 3.1 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 2.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.4 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.7 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.1 1.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.4 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.3 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.1 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 1.1 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 1.9 GO:0019894 kinesin binding(GO:0019894)
0.1 0.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.5 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.1 1.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.3 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.4 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 1.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.4 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.1 0.7 GO:0097001 sphingolipid binding(GO:0046625) ceramide binding(GO:0097001)
0.1 1.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.8 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 1.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.5 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 1.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.6 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 0.3 GO:0008887 glycerate kinase activity(GO:0008887)
0.1 0.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.3 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.7 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.6 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.6 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.6 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.5 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 0.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 0.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.9 GO:0002039 p53 binding(GO:0002039)
0.1 0.4 GO:0045309 protein phosphorylated amino acid binding(GO:0045309) phosphoprotein binding(GO:0051219)
0.1 1.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.8 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:1901612 phosphatidic acid binding(GO:0070300) phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 0.7 GO:0048018 death receptor binding(GO:0005123) receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 2.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0005335 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.0 1.8 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.5 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 1.4 GO:0017069 snRNA binding(GO:0017069)
0.0 0.7 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 0.2 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.2 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.0 0.5 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.1 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 1.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.3 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.7 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.1 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 1.1 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.4 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 2.1 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 2.5 GO:0004386 helicase activity(GO:0004386)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.5 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.5 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.3 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.2 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 3.5 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.6 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.3 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049) nucleocytoplasmic transporter activity(GO:0005487)
0.0 1.0 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 1.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.4 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.6 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 1.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.0 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.0 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.0 0.4 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 4.0 GO:0005096 GTPase activator activity(GO:0005096)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 3.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 0.3 PID IGF1 PATHWAY IGF1 pathway
0.1 1.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.5 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 2.0 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.8 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.9 PID P73PATHWAY p73 transcription factor network
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.2 PID ATR PATHWAY ATR signaling pathway
0.0 0.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 2.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.2 1.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 0.5 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.2 4.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 0.8 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 0.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 1.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.6 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.8 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.0 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.6 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling