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PRJNA195909:zebrafish embryo and larva development

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Results for bach1a+bach1b+bach2a+bach2b

Z-value: 0.98

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Transcription factors associated with bach1a+bach1b+bach2a+bach2b

Gene Symbol Gene ID Gene Info
bach1b
ENSDARG00000002196 BTB and CNC homology 1, basic leucine zipper transcription factor 1 b
bach2b
ENSDARG00000004074 BTB and CNC homology 1, basic leucine zipper transcription factor 2b
bach2a
ENSDARG00000036569 BTB and CNC homology 1, basic leucine zipper transcription factor 2a
bach1a
ENSDARG00000062553 BTB and CNC homology 1, basic leucine zipper transcription factor 1 a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bach2bdr11_v1_chr20_-_24122881_24122881-0.924.9e-04Click!
bach2adr11_v1_chr17_+_15559046_155590460.694.1e-02Click!
bach1adr11_v1_chr15_-_8177919_81779190.618.0e-02Click!
bach1bdr11_v1_chr10_+_25369254_25369254-0.531.4e-01Click!

Activity profile of bach1a+bach1b+bach2a+bach2b motif

Sorted Z-values of bach1a+bach1b+bach2a+bach2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_27570333 1.98 ENSDART00000146562
ENSDART00000179060
si:dkeyp-46h3.5
si:dkeyp-46h3.8
si:dkeyp-46h3.5
si:dkeyp-46h3.8
chr16_-_24832038 1.89 ENSDART00000153731
si:dkey-79d12.5
si:dkey-79d12.5
chr8_+_8671229 1.57 ENSDART00000131963
usp11
ubiquitin specific peptidase 11
chr24_-_33366188 1.44 ENSDART00000074161
slc4a2b
solute carrier family 4 (anion exchanger), member 2b
chr11_+_37638873 1.18 ENSDART00000186384
ENSDART00000184291
ENSDART00000131782
ENSDART00000140502
sh2d5
SH2 domain containing 5
chr17_+_32623931 1.12 ENSDART00000144217
ctsba
cathepsin Ba
chr4_+_5317483 1.12 ENSDART00000150366
si:ch211-214j24.10
si:ch211-214j24.10
chr20_+_35445462 1.09 ENSDART00000124497
tdrd6
tudor domain containing 6
chr24_-_5691956 1.05 ENSDART00000189112
dia1b
deleted in autism 1b
chr3_-_3448095 1.02 ENSDART00000078886
A2ML1 (1 of many)
si:dkey-46g23.5
chr20_-_16548912 1.00 ENSDART00000137601
ches1
checkpoint suppressor 1
chr3_+_19687217 0.98 ENSDART00000141937
tlk2
tousled-like kinase 2
chr23_+_2728095 0.98 ENSDART00000066086
zgc:114123
zgc:114123
chr19_-_27564458 0.96 ENSDART00000123155
si:dkeyp-46h3.6
si:dkeyp-46h3.6
chr8_+_48965767 0.93 ENSDART00000008058
aak1a
AP2 associated kinase 1a
chr20_+_42537768 0.93 ENSDART00000134066
ENSDART00000153434
si:dkeyp-93d12.1
si:dkeyp-93d12.1
chr1_+_46598502 0.91 ENSDART00000132861
cab39l
calcium binding protein 39-like
chr23_-_37113396 0.90 ENSDART00000102886
ENSDART00000134461
zgc:193690
zgc:193690
chr21_+_13233377 0.88 ENSDART00000142569
specc1lb
sperm antigen with calponin homology and coiled-coil domains 1-like b
chr8_+_48966165 0.88 ENSDART00000165425
aak1a
AP2 associated kinase 1a
chr3_-_24205339 0.88 ENSDART00000157135
si:dkey-110g7.8
si:dkey-110g7.8
chr3_-_584950 0.87 ENSDART00000164752
dicp1.1
diverse immunoglobulin domain-containing protein 1.1
chr5_+_35786141 0.85 ENSDART00000022043
ENSDART00000127383
stard8
StAR-related lipid transfer (START) domain containing 8
chr5_-_20678300 0.84 ENSDART00000088639
wscd2
WSC domain containing 2
chr14_+_30774032 0.81 ENSDART00000139552
atl3
atlastin 3
chr2_+_15100742 0.79 ENSDART00000027171
f3b
coagulation factor IIIb
chr18_+_3243292 0.78 ENSDART00000166580
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr2_-_23391266 0.78 ENSDART00000159048
ivns1abpb
influenza virus NS1A binding protein b
chr16_+_48714048 0.77 ENSDART00000148709
ENSDART00000150121
brd2b
bromodomain containing 2b
chr25_-_13408760 0.76 ENSDART00000154445
gins3
GINS complex subunit 3
chr13_+_2357637 0.76 ENSDART00000017148
gclc
glutamate-cysteine ligase, catalytic subunit
chr7_+_34549198 0.76 ENSDART00000173784
fhod1
formin homology 2 domain containing 1
chr11_-_11965033 0.75 ENSDART00000193683
abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr22_-_6562618 0.75 ENSDART00000106100
zgc:171490
zgc:171490
chr7_+_26649319 0.75 ENSDART00000173823
ENSDART00000101053
tp53i11a
tumor protein p53 inducible protein 11a
chr12_-_27212596 0.75 ENSDART00000153101
psme3
proteasome activator subunit 3
chr8_-_14067517 0.74 ENSDART00000140948
dedd
death effector domain containing
chr9_-_41025062 0.72 ENSDART00000002053
pms1
PMS1 homolog 1, mismatch repair system component
chr7_+_34549377 0.70 ENSDART00000191814
fhod1
formin homology 2 domain containing 1
chr23_+_17522867 0.70 ENSDART00000002714
slc17a9b
solute carrier family 17 (vesicular nucleotide transporter), member 9b
chr24_-_31090948 0.69 ENSDART00000176799
hccsb
holocytochrome c synthase b
chr25_-_11026907 0.69 ENSDART00000156846
mespbb
mesoderm posterior bb
chr1_-_10577945 0.68 ENSDART00000179237
ENSDART00000040502
ENSDART00000186876
trpc5a
transient receptor potential cation channel, subfamily C, member 5a
chr3_+_35498119 0.67 ENSDART00000178963
tnrc6a
trinucleotide repeat containing 6a
chr6_+_51713076 0.67 ENSDART00000146281
ripor3
RIPOR family member 3
chr4_+_45274792 0.66 ENSDART00000150295
znf1138
zinc finger protein 1138
chr22_+_35089031 0.66 ENSDART00000076040
srfa
serum response factor a
chr2_-_7605121 0.65 ENSDART00000182099
CABZ01021599.1

chr6_+_33885828 0.64 ENSDART00000179994
gpbp1l1
GC-rich promoter binding protein 1-like 1
chr5_-_49951106 0.64 ENSDART00000135954
fam172a
family with sequence similarity 172, member A
chr19_+_48359259 0.64 ENSDART00000167353
sgo1
shugoshin 1
chr18_+_44849809 0.63 ENSDART00000097328
arfgap2
ADP-ribosylation factor GTPase activating protein 2
chr22_+_26600834 0.62 ENSDART00000157411
adcy9
adenylate cyclase 9
chr15_-_30450898 0.62 ENSDART00000156584
msi2b
musashi RNA-binding protein 2b
chr11_+_45219558 0.61 ENSDART00000167828
tmc6b
transmembrane channel-like 6b
chr5_+_20035284 0.61 ENSDART00000191808
sgsm1a
small G protein signaling modulator 1a
chr17_+_19626479 0.61 ENSDART00000044993
ENSDART00000131863
rgs7a
regulator of G protein signaling 7a
chr18_+_3169579 0.60 ENSDART00000164724
ENSDART00000186340
ENSDART00000181247
ENSDART00000168056
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr21_-_28640316 0.60 ENSDART00000128237
nrg2a
neuregulin 2a
chr23_+_24501918 0.59 ENSDART00000078824
szrd1
SUZ RNA binding domain containing 1
chr5_+_27488975 0.59 ENSDART00000123635
sfrp1a
secreted frizzled-related protein 1a
chr10_+_32050906 0.58 ENSDART00000137373
si:ch211-266i6.3
si:ch211-266i6.3
chr20_-_34069956 0.58 ENSDART00000017941
tprb
translocated promoter region b, nuclear basket protein
chr1_+_58677434 0.57 ENSDART00000158488
LO017784.1

chr8_+_50534948 0.56 ENSDART00000174435
PEBP4
phosphatidylethanolamine binding protein 4
chr16_+_27543893 0.56 ENSDART00000182421
si:ch211-197h24.6
si:ch211-197h24.6
chr1_+_41690402 0.56 ENSDART00000177298
fbxo41
F-box protein 41
chr19_-_27564980 0.56 ENSDART00000171967
si:dkeyp-46h3.8
si:dkeyp-46h3.8
chr10_-_32877348 0.56 ENSDART00000018977
ENSDART00000133421
rabgef1
RAB guanine nucleotide exchange factor (GEF) 1
chr5_+_34549845 0.55 ENSDART00000139317
aif1l
allograft inflammatory factor 1-like
chr14_-_493029 0.54 ENSDART00000115093
zgc:172215
zgc:172215
chr15_-_43978141 0.54 ENSDART00000041249
chordc1a
cysteine and histidine-rich domain (CHORD) containing 1a
chr25_-_35045250 0.54 ENSDART00000156508
ENSDART00000126590
zgc:114046
zgc:114046
chr18_+_15841449 0.53 ENSDART00000141800
ENSDART00000091349
eea1
early endosome antigen 1
chr15_-_38129845 0.53 ENSDART00000057095
si:dkey-24p1.1
si:dkey-24p1.1
chr15_+_40188076 0.51 ENSDART00000063779
efhd1
EF-hand domain family, member D1
chr20_-_43723860 0.51 ENSDART00000122051
mixl1
Mix paired-like homeobox
chr14_-_36763302 0.51 ENSDART00000074786
ctso
cathepsin O
chr7_-_5487593 0.51 ENSDART00000136594
arhgef11
Rho guanine nucleotide exchange factor (GEF) 11
chr15_+_25489406 0.50 ENSDART00000162482
zgc:152863
zgc:152863
chr3_+_29476085 0.50 ENSDART00000184495
ENSDART00000181058
fam83fa
family with sequence similarity 83, member Fa
chr12_-_27212880 0.49 ENSDART00000002835
psme3
proteasome activator subunit 3
chr9_+_28140089 0.49 ENSDART00000046880
plekhm3
pleckstrin homology domain containing, family M, member 3
chr20_-_34767472 0.49 ENSDART00000186710
paqr8
progestin and adipoQ receptor family member VIII
chr14_+_30774515 0.49 ENSDART00000191666
atl3
atlastin 3
chr23_-_37113215 0.49 ENSDART00000146835
zgc:193690
zgc:193690
chr15_-_23442891 0.48 ENSDART00000059376
ube4a
ubiquitination factor E4A (UFD2 homolog, yeast)
chr21_-_30254185 0.48 ENSDART00000101054
dnajc18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr22_+_31023205 0.48 ENSDART00000111561
zmp:0000000735
zmp:0000000735
chr11_-_14102131 0.48 ENSDART00000085158
ENSDART00000191962
tmem259
transmembrane protein 259
chr19_-_5805923 0.48 ENSDART00000134340
si:ch211-264f5.8
si:ch211-264f5.8
chr1_+_52137528 0.47 ENSDART00000007079
ENSDART00000074265
asna1
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr7_+_14005111 0.47 ENSDART00000187365
furina
furin (paired basic amino acid cleaving enzyme) a
chr2_+_36109002 0.47 ENSDART00000158978
traj28
T-cell receptor alpha joining 28
chr8_-_38201415 0.46 ENSDART00000155189
pdlim2
PDZ and LIM domain 2 (mystique)
chr4_-_64605318 0.46 ENSDART00000170391
znf1099
zinc finger protein 1099
chr17_+_28675120 0.46 ENSDART00000159067
hectd1
HECT domain containing 1
chr25_+_18583877 0.46 ENSDART00000148741
met
MET proto-oncogene, receptor tyrosine kinase
chr21_+_3093419 0.45 ENSDART00000162520
SHC3
SHC adaptor protein 3
chr17_+_51682429 0.45 ENSDART00000004379
nol10
nucleolar protein 10
chr11_-_39118882 0.45 ENSDART00000113185
ENSDART00000156526
ap5b1
adaptor-related protein complex 5, beta 1 subunit
chr24_-_21973365 0.44 ENSDART00000081204
ENSDART00000030592
acot9.1
acyl-CoA thioesterase 9, tandem duplicate 1
chr8_-_34402839 0.44 ENSDART00000180173
ENSDART00000191588
ENSDART00000186376
gapvd1
GTPase activating protein and VPS9 domains 1
chr12_-_29233738 0.44 ENSDART00000153175
si:ch211-214e3.5
si:ch211-214e3.5
chr4_+_64921810 0.44 ENSDART00000157654
BX928743.1

chr24_+_30215475 0.43 ENSDART00000164717
si:ch73-358j7.2
si:ch73-358j7.2
chr7_-_19638319 0.43 ENSDART00000163686
si:ch211-212k18.4
si:ch211-212k18.4
chr9_+_22388686 0.43 ENSDART00000182731
ENSDART00000181462
dgkg
diacylglycerol kinase, gamma
chr22_-_5839686 0.43 ENSDART00000145406
si:rp71-36a1.5
si:rp71-36a1.5
chr19_+_26072624 0.43 ENSDART00000147627
jarid2b
jumonji, AT rich interactive domain 2b
chr14_+_28464736 0.42 ENSDART00000019003
psmd10
proteasome 26S subunit, non-ATPase 10
chr1_+_46598764 0.42 ENSDART00000053240
cab39l
calcium binding protein 39-like
chr23_-_36441693 0.42 ENSDART00000024354
csad
cysteine sulfinic acid decarboxylase
chr7_+_22688781 0.42 ENSDART00000173509
ugt5g1
UDP glucuronosyltransferase 5 family, polypeptide G1
chr25_-_7753207 0.41 ENSDART00000126499
phf21ab
PHD finger protein 21Ab
chr2_+_47945359 0.41 ENSDART00000098054
ftr19
finTRIM family, member 19
chr19_+_24575077 0.41 ENSDART00000167469
si:dkeyp-92c9.4
si:dkeyp-92c9.4
chr21_-_11657043 0.41 ENSDART00000141297
cast
calpastatin
chr15_-_36727462 0.40 ENSDART00000085971
nphs1
nephrosis 1, congenital, Finnish type (nephrin)
chr13_+_7575563 0.40 ENSDART00000146592
gbf1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr4_-_64604842 0.39 ENSDART00000169862
znf1099
zinc finger protein 1099
chr23_+_7548797 0.39 ENSDART00000006765
tm9sf4
transmembrane 9 superfamily protein member 4
chr4_-_56157199 0.39 ENSDART00000169806
si:ch211-207e19.15
si:ch211-207e19.15
chr19_-_7272921 0.39 ENSDART00000102075
ENSDART00000132887
ENSDART00000130234
ENSDART00000193535
ENSDART00000136528
rxrba
retinoid x receptor, beta a
chr8_-_18667693 0.38 ENSDART00000100516
stap2b
signal transducing adaptor family member 2b
chr12_-_3077395 0.38 ENSDART00000002867
ENSDART00000126315
rfng
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr11_+_19370447 0.38 ENSDART00000186154
prickle2b
prickle homolog 2b
chr11_+_19370717 0.38 ENSDART00000165906
prickle2b
prickle homolog 2b
chr24_-_6628359 0.38 ENSDART00000169731
arhgap21a
Rho GTPase activating protein 21a
chr18_+_618005 0.37 ENSDART00000189667
prtga
protogenin homolog a (Gallus gallus)
chr2_+_47944967 0.37 ENSDART00000135584
ftr19
finTRIM family, member 19
chr5_-_19052184 0.36 ENSDART00000133330
fam214b
family with sequence similarity 214, member B
chr11_+_37905630 0.36 ENSDART00000170303
si:ch211-112f3.4
si:ch211-112f3.4
chr16_-_36746837 0.36 ENSDART00000189276
ENSDART00000085228
pik3r4
phosphoinositide-3-kinase, regulatory subunit 4
chr21_+_26612777 0.36 ENSDART00000142667
esrra
estrogen-related receptor alpha
chr21_+_37477001 0.36 ENSDART00000114778
amot
angiomotin
chr23_+_45200481 0.36 ENSDART00000004357
ENSDART00000111126
ENSDART00000193560
ENSDART00000190476
psip1b
PC4 and SFRS1 interacting protein 1b
chr1_+_47165842 0.35 ENSDART00000053152
ENSDART00000167051
cbr1
carbonyl reductase 1
chr24_-_24797455 0.35 ENSDART00000138741
pde7a
phosphodiesterase 7A
chr15_+_714203 0.34 ENSDART00000153847
si:dkey-7i4.24
si:dkey-7i4.24
chr4_+_68087932 0.34 ENSDART00000150494
znf1096
zinc finger protein 1096
chr11_+_44617021 0.34 ENSDART00000158887
rbm34
RNA binding motif protein 34
chr18_-_37355666 0.34 ENSDART00000098914
yap1
Yes-associated protein 1
chr5_-_57480660 0.33 ENSDART00000147875
ENSDART00000142776
si:ch211-202f5.2
si:ch211-202f5.2
chr9_+_29323163 0.33 ENSDART00000184908
oxgr1b
oxoglutarate (alpha-ketoglutarate) receptor 1b
chr4_-_17822447 0.33 ENSDART00000185502
dnajb9b
DnaJ (Hsp40) homolog, subfamily B, member 9b
chr15_+_24704798 0.33 ENSDART00000192470
LRRC75A
si:dkey-151p21.7
chr5_-_42950963 0.32 ENSDART00000149868
grsf1
G-rich RNA sequence binding factor 1
chr4_+_43408004 0.32 ENSDART00000150476
si:dkeyp-53e4.2
si:dkeyp-53e4.2
chr19_+_4139065 0.32 ENSDART00000172524
si:dkey-218f9.10
si:dkey-218f9.10
chr5_-_33298352 0.32 ENSDART00000015076
zgc:103692
zgc:103692
chr7_+_7696665 0.31 ENSDART00000091099
ino80b
INO80 complex subunit B
chr7_-_5396154 0.31 ENSDART00000172980
arhgef11
Rho guanine nucleotide exchange factor (GEF) 11
chr2_+_17524278 0.31 ENSDART00000165633
pimr196
Pim proto-oncogene, serine/threonine kinase, related 196
chr25_-_37314700 0.30 ENSDART00000017807
igl4v8
immunoglobulin light 4 variable 8
chr5_-_63644938 0.30 ENSDART00000050865
surf4l
surfeit gene 4, like
chr21_+_26620867 0.30 ENSDART00000176008
esrra
estrogen-related receptor alpha
chr4_-_1801519 0.29 ENSDART00000188604
ENSDART00000135749
nudt4b
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr10_+_28428222 0.29 ENSDART00000135003
si:ch211-222e20.4
si:ch211-222e20.4
chr14_-_40821411 0.28 ENSDART00000166621
elf1
E74-like ETS transcription factor 1
chr15_-_30832171 0.28 ENSDART00000152414
ENSDART00000152790
msi2b
musashi RNA-binding protein 2b
chr4_-_4535189 0.27 ENSDART00000057519
zgc:194209
zgc:194209
chr23_-_15878879 0.27 ENSDART00000010119
eef1a2
eukaryotic translation elongation factor 1 alpha 2
chr25_-_11378623 0.27 ENSDART00000166586
enc2
ectodermal-neural cortex 2
chr13_+_1430094 0.27 ENSDART00000169888
si:ch211-165e15.1
si:ch211-165e15.1
chr2_-_898899 0.27 ENSDART00000058289
dusp22b
dual specificity phosphatase 22b
chr13_-_49585385 0.27 ENSDART00000165868
tomm20a
translocase of outer mitochondrial membrane 20
chr19_+_33093577 0.26 ENSDART00000180317
fam91a1
family with sequence similarity 91, member A1
chr16_+_46410520 0.26 ENSDART00000131072
rpz2
rapunzel 2
chr2_+_10007113 0.26 ENSDART00000155213
slc35a3b
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr23_-_4705110 0.25 ENSDART00000144536
ENSDART00000129050
ENSDART00000136399
cnbpa
CCHC-type zinc finger, nucleic acid binding protein a
chr21_-_21020708 0.25 ENSDART00000064032
eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
chr21_+_33459524 0.25 ENSDART00000053205
cd74b
CD74 molecule, major histocompatibility complex, class II invariant chain b
chr18_+_17537344 0.25 ENSDART00000025782
nup93
nucleoporin 93
chr22_-_3595439 0.25 ENSDART00000083308
ptprsa
protein tyrosine phosphatase, receptor type, s, a
chr24_-_21973163 0.25 ENSDART00000131406
acot9.1
acyl-CoA thioesterase 9, tandem duplicate 1
chr3_+_17616201 0.24 ENSDART00000156775
rab5c
RAB5C, member RAS oncogene family
chr23_-_45339439 0.24 ENSDART00000148726
ccdc171
coiled-coil domain containing 171
chr24_-_40009446 0.24 ENSDART00000087422
aoc1
amine oxidase, copper containing 1
chr23_+_25856541 0.24 ENSDART00000145426
ENSDART00000028236
hnf4a
hepatocyte nuclear factor 4, alpha
chr10_+_2529037 0.24 ENSDART00000123467
zmp:0000001301
zmp:0000001301
chr14_+_30774894 0.24 ENSDART00000023054
atl3
atlastin 3
chr4_+_58057168 0.24 ENSDART00000161097
si:dkey-57k17.1
si:dkey-57k17.1
chr5_-_42123794 0.24 ENSDART00000051135
emc6
ER membrane protein complex subunit 6
chr5_+_59534286 0.23 ENSDART00000189341
gtf2ird1
GTF2I repeat domain containing 1
chr16_+_41517188 0.23 ENSDART00000049976
si:dkey-11p23.7
si:dkey-11p23.7
chr5_+_42064144 0.23 ENSDART00000035235
si:ch211-202a12.4
si:ch211-202a12.4
chr24_+_42131564 0.23 ENSDART00000153854
wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr4_+_69624049 0.22 ENSDART00000170052
znf1030
zinc finger protein 1030
chr16_+_32136550 0.22 ENSDART00000147526
sphk2
sphingosine kinase 2
chr15_+_17074185 0.22 ENSDART00000046648
clptm1
cleft lip and palate associated transmembrane protein 1
chr7_-_29723761 0.22 ENSDART00000173560
vps13c
vacuolar protein sorting 13 homolog C (S. cerevisiae)
chr9_+_22466218 0.22 ENSDART00000131214
dgkg
diacylglycerol kinase, gamma
chr4_+_47656992 0.22 ENSDART00000161148
znf1040
zinc finger protein 1040
chr16_-_13818061 0.22 ENSDART00000132982
ENSDART00000144856
leng9
leukocyte receptor cluster (LRC) member 9
chr1_+_44360973 0.22 ENSDART00000167568
si:ch211-165a10.5
si:ch211-165a10.5
chr17_-_45247332 0.21 ENSDART00000016815
ttbk2a
tau tubulin kinase 2a
chr17_-_45247151 0.21 ENSDART00000186230
ttbk2a
tau tubulin kinase 2a
chr24_+_31361407 0.20 ENSDART00000162668
cremb
cAMP responsive element modulator b
chr16_+_13818743 0.20 ENSDART00000090191
flcn
folliculin

Network of associatons between targets according to the STRING database.

First level regulatory network of bach1a+bach1b+bach2a+bach2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.2 1.4 GO:0003232 bulbus arteriosus development(GO:0003232)
0.2 0.6 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.2 0.8 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.2 0.6 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.1 0.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.7 GO:0018063 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.1 1.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 1.0 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1 1.6 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.7 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 0.8 GO:1902315 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 1.8 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 1.1 GO:0030719 P granule organization(GO:0030719)
0.1 1.5 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.5 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.1 0.6 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 0.6 GO:0003222 ventricular trabecula myocardium morphogenesis(GO:0003222) trabecula formation(GO:0060343) heart trabecula formation(GO:0060347) skin epidermis development(GO:0098773)
0.1 0.3 GO:0010934 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.6 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.1 1.1 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 0.3 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.1 0.3 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.1 1.4 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.4 GO:0030242 pexophagy(GO:0030242)
0.1 0.4 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.3 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.2 GO:0015824 proline transport(GO:0015824)
0.0 0.2 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.2 GO:0045124 regulation of bone resorption(GO:0045124)
0.0 0.9 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 0.4 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.7 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.5 GO:0021707 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.8 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.2 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.7 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.2 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 0.4 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.5 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 1.2 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 1.4 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.7 GO:0006298 mismatch repair(GO:0006298)
0.0 0.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.2 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.5 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.1 GO:0048242 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.0 0.7 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.4 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.4 GO:0060324 face development(GO:0060324)
0.0 0.5 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 0.2 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.8 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.8 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.6 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 1.9 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.3 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.3 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.0 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.0 0.1 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.5 GO:0051298 centrosome duplication(GO:0051298)
0.0 0.3 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 1.7 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.4 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.3 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.1 GO:0030431 sleep(GO:0030431)
0.0 0.4 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.5 GO:0001706 endoderm formation(GO:0001706)
0.0 0.2 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 1.1 GO:0090504 epiboly(GO:0090504)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0033391 chromatoid body(GO:0033391)
0.3 1.2 GO:0008537 proteasome activator complex(GO:0008537)
0.2 0.8 GO:0000811 GINS complex(GO:0000811)
0.1 1.1 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.7 GO:0032300 mismatch repair complex(GO:0032300)
0.1 0.4 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 1.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.9 GO:0005844 polysome(GO:0005844)
0.0 0.9 GO:0005921 gap junction(GO:0005921)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 1.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.1 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.4 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.4 GO:0035869 ciliary transition zone(GO:0035869)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 1.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.7 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.1 0.6 GO:0035197 siRNA binding(GO:0035197)
0.1 0.8 GO:0043531 ADP binding(GO:0043531)
0.1 0.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.2 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.4 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.3 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 1.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 1.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 1.1 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.7 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.3 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.0 0.5 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.6 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 1.4 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.4 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 1.5 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 2.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 3.4 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.2 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.8 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 1.3 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 0.2 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.7 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells