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PRJNA195909:zebrafish embryo and larva development

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Results for cebpd

Z-value: 0.77

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Transcription factors associated with cebpd

Gene Symbol Gene ID Gene Info
cebpd
ENSDARG00000087303 CCAAT enhancer binding protein delta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cebpddr11_v1_chr24_+_35564668_355646680.916.3e-04Click!

Activity profile of cebpd motif

Sorted Z-values of cebpd motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_32665283 1.82 ENSDART00000038364
ca2
carbonic anhydrase II
chr5_-_63509581 1.66 ENSDART00000097325
c5
complement component 5
chr16_+_23984755 1.66 ENSDART00000145328
apoc2
apolipoprotein C-II
chr14_-_12071679 1.50 ENSDART00000165581
tmsb1
thymosin beta 1
chr5_-_20195350 1.47 ENSDART00000139675
dao.1
D-amino-acid oxidase, tandem duplicate 1
chr14_-_12071447 1.42 ENSDART00000166116
tmsb1
thymosin beta 1
chr23_+_44732863 1.40 ENSDART00000160044
ENSDART00000172268
atp1b2a
ATPase Na+/K+ transporting subunit beta 2a
chr1_-_10071422 1.35 ENSDART00000135522
ENSDART00000033118
fga
fibrinogen alpha chain
chr4_-_17409533 1.33 ENSDART00000011943
pah
phenylalanine hydroxylase
chr15_-_17960228 1.31 ENSDART00000155898
phldb1b
pleckstrin homology-like domain, family B, member 1b
chr6_-_11780070 1.24 ENSDART00000151195
march7
membrane-associated ring finger (C3HC4) 7
chr3_-_46818001 1.04 ENSDART00000166505
elavl3
ELAV like neuron-specific RNA binding protein 3
chr9_+_3388099 1.02 ENSDART00000019910
dlx1a
distal-less homeobox 1a
chr13_+_23157053 0.98 ENSDART00000162359
sorbs1
sorbin and SH3 domain containing 1
chr5_-_25583125 0.97 ENSDART00000031665
ENSDART00000145353
anxa1a
annexin A1a
chr5_-_25582721 0.96 ENSDART00000123986
anxa1a
annexin A1a
chr15_+_32711663 0.92 ENSDART00000157854
ENSDART00000167515
postnb
periostin, osteoblast specific factor b
chr17_-_43466317 0.91 ENSDART00000155313
hspa4l
heat shock protein 4 like
chr16_+_23984179 0.89 ENSDART00000175879
apoc2
apolipoprotein C-II
chr23_+_11285662 0.87 ENSDART00000111028
chl1a
cell adhesion molecule L1-like a
chr16_+_20895904 0.83 ENSDART00000052662
hoxa13b
homeobox A13b
chr6_+_9130989 0.83 ENSDART00000162588
rgn
regucalcin
chr2_-_50298337 0.81 ENSDART00000155125
cntnap2b
contactin associated protein like 2b
chr22_-_17595310 0.81 ENSDART00000099056
gpx4a
glutathione peroxidase 4a
chr3_+_23703704 0.79 ENSDART00000024256
hoxb6a
homeobox B6a
chr16_+_46111849 0.78 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr10_-_20523405 0.76 ENSDART00000114824
ddhd2
DDHD domain containing 2
chr12_+_25775734 0.74 ENSDART00000024415
ENSDART00000149198
epas1a
endothelial PAS domain protein 1a
chr7_+_4162994 0.72 ENSDART00000172800
si:ch211-63p21.1
si:ch211-63p21.1
chr12_-_20373058 0.71 ENSDART00000066382
aqp8a.1
aquaporin 8a, tandem duplicate 1
chr20_-_45661049 0.71 ENSDART00000124582
ENSDART00000131251
napbb
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr11_-_24681292 0.70 ENSDART00000089601
olfml3b
olfactomedin-like 3b
chr6_-_345503 0.70 ENSDART00000168901
pde6ha
phosphodiesterase 6H, cGMP-specific, cone, gamma, paralog a
chr17_-_10838434 0.69 ENSDART00000064597
lgals3b
lectin, galactoside binding soluble 3b
chr1_+_14253118 0.69 ENSDART00000161996
cxcl8a
chemokine (C-X-C motif) ligand 8a
chr8_-_25011157 0.68 ENSDART00000078795
ahcyl1
adenosylhomocysteinase-like 1
chr19_-_15281996 0.67 ENSDART00000103784
edn2
endothelin 2
chr17_+_10318071 0.67 ENSDART00000161844
foxa1
forkhead box A1
chr11_-_6265574 0.67 ENSDART00000181974
ENSDART00000104405
ccl25b
chemokine (C-C motif) ligand 25b
chr7_+_63325819 0.67 ENSDART00000085612
ENSDART00000161436
pcdh7b
protocadherin 7b
chr16_-_17072440 0.65 ENSDART00000002493
ENSDART00000178443
tnfrsf1a
tumor necrosis factor receptor superfamily, member 1a
chr1_+_25801648 0.63 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr9_+_219124 0.63 ENSDART00000161484
map3k12
mitogen-activated protein kinase kinase kinase 12
chr9_-_6927587 0.61 ENSDART00000059092
tmem182a
transmembrane protein 182a
chr7_-_52963493 0.61 ENSDART00000052029
cart3
cocaine- and amphetamine-regulated transcript 3
chr14_+_21106444 0.60 ENSDART00000075744
ENSDART00000132363
aldob
aldolase b, fructose-bisphosphate
chr9_+_32301017 0.60 ENSDART00000127916
ENSDART00000183298
ENSDART00000143103
hspe1
heat shock 10 protein 1
chr8_+_4368534 0.60 ENSDART00000015214
pptc7a
PTC7 protein phosphatase homolog a
chr4_-_5302162 0.60 ENSDART00000177099
SNAP91 (1 of many)
si:ch211-214j24.9
chr17_-_52091999 0.59 ENSDART00000019766
tgfb3
transforming growth factor, beta 3
chr11_+_23933016 0.58 ENSDART00000000486
cntn2
contactin 2
chr14_+_21107032 0.56 ENSDART00000138319
ENSDART00000139103
ENSDART00000184735
aldob
aldolase b, fructose-bisphosphate
chr16_+_14029283 0.55 ENSDART00000146165
ENSDART00000132075
rusc1
RUN and SH3 domain containing 1
chr7_-_66452792 0.53 ENSDART00000170701
ENSDART00000082604
galnt18b
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18b
chr5_-_69437422 0.53 ENSDART00000073676
isca1
iron-sulfur cluster assembly 1
chr21_-_39058490 0.52 ENSDART00000114885
aldh3a2b
aldehyde dehydrogenase 3 family, member A2b
chr19_+_1370504 0.51 ENSDART00000158946
dgat1a
diacylglycerol O-acyltransferase 1a
chr16_+_50289916 0.50 ENSDART00000168861
ENSDART00000167332
hamp
hepcidin antimicrobial peptide
chr25_-_2081371 0.50 ENSDART00000104915
ENSDART00000156925
wnt7bb
wingless-type MMTV integration site family, member 7Bb
chr1_+_26071869 0.50 ENSDART00000059264
mxd4
MAX dimerization protein 4
chr24_+_119680 0.49 ENSDART00000061973
tgfbr1b
transforming growth factor, beta receptor 1 b
chr25_-_17239008 0.49 ENSDART00000151965
ENSDART00000152106
ENSDART00000152107
ccnd2a
cyclin D2, a
chr19_-_44054930 0.49 ENSDART00000151084
ENSDART00000150991
ENSDART00000005191
uqcrb
ubiquinol-cytochrome c reductase binding protein
chr13_+_28705143 0.49 ENSDART00000183338
ldb1a
LIM domain binding 1a
chr9_+_32301456 0.49 ENSDART00000078608
ENSDART00000185153
ENSDART00000144947
hspe1
heat shock 10 protein 1
chr4_-_5302866 0.49 ENSDART00000138590
SNAP91 (1 of many)
si:ch211-214j24.9
chr18_-_20869175 0.49 ENSDART00000090079
synm
synemin, intermediate filament protein
chr5_+_3501859 0.48 ENSDART00000080486
ywhag1
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1
chr25_-_3469576 0.48 ENSDART00000186738
hbp1
HMG-box transcription factor 1
chr5_-_43935460 0.47 ENSDART00000166152
ENSDART00000188969
si:ch211-204c21.1
si:ch211-204c21.1
chr11_+_37251825 0.47 ENSDART00000169804
il17rc
interleukin 17 receptor C
chr11_+_43419809 0.47 ENSDART00000172982
slc29a1b
solute carrier family 29 (equilibrative nucleoside transporter), member 1b
chr6_-_48094342 0.46 ENSDART00000137458
slc2a1b
solute carrier family 2 (facilitated glucose transporter), member 1b
chr18_+_507835 0.46 ENSDART00000189701
nedd4a
neural precursor cell expressed, developmentally down-regulated 4a
chr21_+_11969603 0.45 ENSDART00000142247
ENSDART00000140652
mlnl
motilin-like
chr1_+_51479128 0.44 ENSDART00000028018
meis1a
Meis homeobox 1 a
chr14_-_38929885 0.44 ENSDART00000148737
btk
Bruton agammaglobulinemia tyrosine kinase
chr8_-_23701880 0.43 ENSDART00000139897
si:ch73-237c6.1
si:ch73-237c6.1
chr19_-_9829965 0.43 ENSDART00000136842
ENSDART00000142766
cacng8a
calcium channel, voltage-dependent, gamma subunit 8a
chr9_-_7238839 0.43 ENSDART00000142726
creg2
cellular repressor of E1A-stimulated genes 2
chr9_+_9502610 0.42 ENSDART00000061525
ENSDART00000125174
nr1i2
nuclear receptor subfamily 1, group I, member 2
chr22_-_18491813 0.42 ENSDART00000105419
si:ch211-212d10.2
si:ch211-212d10.2
chr21_-_40174647 0.41 ENSDART00000183738
ENSDART00000076840
ENSDART00000145109
slco2b1
solute carrier organic anion transporter family, member 2B1
chr5_-_43935119 0.41 ENSDART00000142271
si:ch211-204c21.1
si:ch211-204c21.1
chr8_-_23684659 0.41 ENSDART00000136865
cfp
complement factor properdin
chr5_-_58840971 0.40 ENSDART00000050932
tmem136b
transmembrane protein 136b
chr22_-_26175237 0.40 ENSDART00000108737
c3b.2
complement component c3b, tandem duplicate 2
chr17_+_30587333 0.40 ENSDART00000156500
nhsl1a
NHS-like 1a
chr12_-_1085227 0.39 ENSDART00000169936
sox8a
SRY (sex determining region Y)-box 8a
chr2_-_58257624 0.39 ENSDART00000098940
foxl2b
forkhead box L2b
chr9_+_48415043 0.37 ENSDART00000159930
lrp2a
low density lipoprotein receptor-related protein 2a
chr5_+_53482597 0.37 ENSDART00000180333
BX323994.1

chr18_+_26899316 0.36 ENSDART00000050230
tspan3a
tetraspanin 3a
chr15_-_17869115 0.36 ENSDART00000112838
atf5b
activating transcription factor 5b
chr1_+_50538839 0.35 ENSDART00000020412
pkd2
polycystic kidney disease 2
chr19_+_8606883 0.35 ENSDART00000054469
ENSDART00000185264
s100a10a
S100 calcium binding protein A10a
chr21_-_5007109 0.35 ENSDART00000187042
ENSDART00000097796
ENSDART00000146766
rnf165a
ring finger protein 165a
chr12_+_35119762 0.35 ENSDART00000085774
si:ch73-127m5.1
si:ch73-127m5.1
chr22_+_27090136 0.33 ENSDART00000136770
si:dkey-246e1.3
si:dkey-246e1.3
chr5_-_45894802 0.33 ENSDART00000097648
crfb6
cytokine receptor family member b6
chr5_+_32162684 0.33 ENSDART00000134472
taok3b
TAO kinase 3b
chr16_+_44298902 0.33 ENSDART00000114795
dpys
dihydropyrimidinase
chr22_-_10487490 0.32 ENSDART00000064798
aspn
asporin (LRR class 1)
chr17_-_17764801 0.32 ENSDART00000155261
slirp
SRA stem-loop interacting RNA binding protein
chr8_-_23702295 0.32 ENSDART00000162296
cfp
complement factor properdin
chr19_+_41080240 0.32 ENSDART00000087295
ppp1r9a
protein phosphatase 1, regulatory subunit 9A
chr15_-_17868870 0.31 ENSDART00000170950
atf5b
activating transcription factor 5b
chr20_-_40755614 0.30 ENSDART00000061247
cx32.3
connexin 32.3
chr10_+_38593645 0.30 ENSDART00000011573
mmp13a
matrix metallopeptidase 13a
chr25_+_7784582 0.30 ENSDART00000155016
dgkzb
diacylglycerol kinase, zeta b
chr7_-_7845540 0.30 ENSDART00000166280
cxcl8b.1
chemokine (C-X-C motif) ligand 8b, duplicate 1
chr12_-_32183164 0.28 ENSDART00000191269
ENSDART00000173549
SMIM36
si:ch73-256g18.2
chr23_+_25305431 0.28 ENSDART00000143291
RPL41
si:dkey-151g10.6
chr10_+_38526496 0.28 ENSDART00000144329
acer3
alkaline ceramidase 3
chr24_-_36727922 0.27 ENSDART00000135142
si:ch73-334d15.1
si:ch73-334d15.1
chr15_-_20939579 0.25 ENSDART00000152371
usp2a
ubiquitin specific peptidase 2a
chr20_-_27381691 0.24 ENSDART00000010293
serpina10a
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10a
chr7_-_22941472 0.22 ENSDART00000190334
tnfsf10l
TNF superfamily member 10, like
chr9_+_38292947 0.22 ENSDART00000146663
tfcp2l1
transcription factor CP2-like 1
chr20_+_23440632 0.22 ENSDART00000180685
ENSDART00000042820
si:dkey-90m5.4
si:dkey-90m5.4
chr8_-_36412936 0.21 ENSDART00000159276
si:zfos-2070c2.3
si:zfos-2070c2.3
chr2_-_10098191 0.20 ENSDART00000138081
bcl6ab
B-cell CLL/lymphoma 6a, genome duplicate b
chr9_-_35069645 0.20 ENSDART00000122679
ENSDART00000077908
ENSDART00000077894
ENSDART00000125536
appb
amyloid beta (A4) precursor protein b
chr13_+_28495419 0.20 ENSDART00000025583
fgf8a
fibroblast growth factor 8a
chr23_-_36003441 0.19 ENSDART00000164699
calcoco1a
calcium binding and coiled-coil domain 1a
chr7_-_13362590 0.19 ENSDART00000091616
sdhaf2
succinate dehydrogenase complex assembly factor 2
chr4_+_12113105 0.18 ENSDART00000182399
tmem178b
transmembrane protein 178B
chr19_+_7735157 0.18 ENSDART00000186717
tuft1b
tuftelin 1b
chr11_-_12998400 0.17 ENSDART00000018614
chrna4b
cholinergic receptor, nicotinic, alpha 4b
chr5_-_29488245 0.17 ENSDART00000047719
ENSDART00000141154
ENSDART00000171165
cacna1ba
calcium channel, voltage-dependent, N type, alpha 1B subunit, a
chr22_+_24645325 0.17 ENSDART00000159531
lpar3
lysophosphatidic acid receptor 3
chr16_-_38001040 0.16 ENSDART00000133861
ENSDART00000138711
ENSDART00000143846
ENSDART00000146564
si:ch211-198c19.3
si:ch211-198c19.3
chr2_-_30460293 0.16 ENSDART00000113193
cbln2a
cerebellin 2a precursor
chr21_+_29227224 0.15 ENSDART00000013641
adra1ba
adrenoceptor alpha 1Ba
chr16_+_49601838 0.15 ENSDART00000168570
ENSDART00000159236
si:dkey-82o10.4
si:dkey-82o10.4
chr8_-_39739627 0.15 ENSDART00000135422
ENSDART00000067844
si:ch211-170d8.5
si:ch211-170d8.5
chr2_-_51772438 0.13 ENSDART00000170241
BX908782.2
Danio rerio three-finger protein 5 (LOC100003647), mRNA.
chr18_-_40905901 0.13 ENSDART00000064848
pglyrp5
peptidoglycan recognition protein 5
chr6_-_10912424 0.12 ENSDART00000036456
cycsb
cytochrome c, somatic b
chr17_-_20236228 0.12 ENSDART00000136490
ENSDART00000029380
bnip4
BCL2 interacting protein 4
chr20_+_2950005 0.12 ENSDART00000135919
amd1
adenosylmethionine decarboxylase 1
chr2_-_49860723 0.11 ENSDART00000083690
blvra
biliverdin reductase A
chr7_+_67733759 0.11 ENSDART00000172015
cyb5b
cytochrome b5 type B
chr14_-_38809561 0.11 ENSDART00000159159
sil1
SIL1 nucleotide exchange factor
chr8_+_26253252 0.11 ENSDART00000142031
slc26a6
solute carrier family 26, member 6
chr12_+_36109507 0.11 ENSDART00000175409
map2k6
mitogen-activated protein kinase kinase 6
chr24_-_25184553 0.11 ENSDART00000166917
plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr25_-_16987020 0.11 ENSDART00000073419
ccnd2a
cyclin D2, a
chr22_+_15336752 0.10 ENSDART00000139070
sult3st2
sulfotransferase family 3, cytosolic sulfotransferase 2
chr21_+_45510448 0.10 ENSDART00000160494
ENSDART00000167914
fnip1
folliculin interacting protein 1
chr22_+_18469004 0.10 ENSDART00000061430
cilp2
cartilage intermediate layer protein 2
chr25_-_19443421 0.10 ENSDART00000067362
cart2
cocaine- and amphetamine-regulated transcript 2
chr8_-_37043900 0.10 ENSDART00000139567
renbp
renin binding protein
chr13_-_18195942 0.09 ENSDART00000079902
slc25a16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr2_-_24348642 0.09 ENSDART00000181739
ano8a
anoctamin 8a
chr8_+_30699429 0.08 ENSDART00000005345
upb1
ureidopropionase, beta
chr17_+_9040165 0.07 ENSDART00000181221
ENSDART00000181846
akap6
A kinase (PRKA) anchor protein 6
chr21_-_43949208 0.07 ENSDART00000150983
camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr2_-_32486080 0.06 ENSDART00000110821
ttc19
tetratricopeptide repeat domain 19
chr24_+_38671054 0.05 ENSDART00000154214
si:ch73-70c5.1
si:ch73-70c5.1
chr7_-_7823662 0.05 ENSDART00000167652
cxcl8b.3
chemokine (C-X-C motif) ligand 8b, duplicate 3
chr24_-_20915050 0.04 ENSDART00000133763
si:ch211-161h7.5
si:ch211-161h7.5
chr15_-_4314042 0.04 ENSDART00000173311
ENSDART00000170562
ECE2
si:ch211-117a13.2
chr9_+_33788389 0.03 ENSDART00000144623
kdm6a
lysine (K)-specific demethylase 6A
chr6_-_14292307 0.03 ENSDART00000177852
ENSDART00000061745
inpp4ab
inositol polyphosphate-4-phosphatase type I Ab
chr2_+_49860722 0.03 ENSDART00000144060
rpl37
ribosomal protein L37
chr20_+_25563105 0.03 ENSDART00000063100
cyp2p6
cytochrome P450, family 2, subfamily P, polypeptide 6
chr7_+_27317174 0.03 ENSDART00000193058
sox6
SRY (sex determining region Y)-box 6
chr14_+_7902374 0.03 ENSDART00000113299
zgc:110843
zgc:110843
chr7_-_22790630 0.02 ENSDART00000173496
si:ch211-15b10.6
si:ch211-15b10.6
chr24_+_11083146 0.02 ENSDART00000009473
zfand1
zinc finger, AN1-type domain 1
chr3_-_43821191 0.01 ENSDART00000186816
snn
stannin
chr24_+_37406535 0.01 ENSDART00000138264
si:ch211-183d21.1
si:ch211-183d21.1
chr10_-_29733194 0.01 ENSDART00000149252
si:ch73-261i21.2
si:ch73-261i21.2
chr20_-_40750953 0.01 ENSDART00000061256
cx28.9
connexin 28.9
chr4_+_71989418 0.01 ENSDART00000170996
parp11
poly(ADP-ribose) polymerase family member 11
chr5_-_26893310 0.00 ENSDART00000126669
lman2lb
lectin, mannose-binding 2-like b

Network of associatons between targets according to the STRING database.

First level regulatory network of cebpd

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0015670 carbon dioxide transport(GO:0015670)
0.4 1.3 GO:0002432 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.4 1.5 GO:0055130 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.3 1.9 GO:0033029 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.3 0.8 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.3 2.6 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 0.7 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.2 0.6 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.2 0.7 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.2 1.0 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 0.8 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.2 0.6 GO:0099543 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.1 0.7 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.7 GO:0014826 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 2.5 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.4 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.4 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.1 0.7 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1 0.7 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 1.3 GO:1902222 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1 1.4 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 1.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.5 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.5 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.1 1.4 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 0.5 GO:0032570 response to progesterone(GO:0032570)
0.1 0.6 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.3 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.1 0.7 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.1 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 0.9 GO:0016203 muscle attachment(GO:0016203)
0.0 0.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.9 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 1.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.4 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.0 0.1 GO:0019483 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.0 0.4 GO:0070293 renal absorption(GO:0070293)
0.0 0.2 GO:0034552 mitochondrial electron transport, succinate to ubiquinone(GO:0006121) respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.2 GO:0021571 rhombomere 5 development(GO:0021571) rhombomere 6 development(GO:0021572) tongue development(GO:0043586) tongue morphogenesis(GO:0043587) taste bud development(GO:0061193) taste bud morphogenesis(GO:0061194) taste bud formation(GO:0061195)
0.0 0.9 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0032978 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.0 0.7 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.4 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 0.3 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.5 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.0 0.2 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.2 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 0.1 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.3 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.6 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.5 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.2 GO:0035094 response to nicotine(GO:0035094)
0.0 0.1 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.1 GO:0008216 spermidine metabolic process(GO:0008216)
0.0 0.4 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.5 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.5 GO:0032924 activin receptor signaling pathway(GO:0032924)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0005577 fibrinogen complex(GO:0005577)
0.3 2.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.2 0.7 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2 2.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 1.4 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 0.8 GO:0033010 paranodal junction(GO:0033010)
0.1 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.7 GO:0001772 immunological synapse(GO:0001772)
0.1 1.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.5 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.5 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.8 GO:0030134 ER to Golgi transport vesicle(GO:0030134)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.3 1.9 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.3 1.0 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.2 0.7 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 0.8 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 1.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.7 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 1.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.7 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 0.5 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 2.0 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.5 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.7 GO:0015250 water channel activity(GO:0015250)
0.1 1.4 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.4 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.7 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 1.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.5 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.5 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 2.2 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.0 GO:0051082 unfolded protein binding(GO:0051082)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.7 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers