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PRJNA195909:zebrafish embryo and larva development

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Results for creb1a+creb1b+crema+cremb

Z-value: 8.89

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Transcription factors associated with creb1a+creb1b+crema+cremb

Gene Symbol Gene ID Gene Info
crema
ENSDARG00000023217 cAMP responsive element modulator a
creb1a
ENSDARG00000053586 cAMP responsive element binding protein 1a
creb1b
ENSDARG00000093420 cAMP responsive element binding protein 1b
cremb
ENSDARG00000102899 cAMP responsive element modulator b
cremb
ENSDARG00000109505 cAMP responsive element modulator b
cremb
ENSDARG00000116064 cAMP responsive element modulator b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
creb1bdr11_v1_chr9_-_28275600_28275600-0.608.9e-02Click!
cremadr11_v1_chr2_-_43168292_43168292-0.561.2e-01Click!
crembdr11_v1_chr24_+_31348595_313487350.472.0e-01Click!
creb1adr11_v1_chr1_-_33556428_335564280.393.0e-01Click!

Activity profile of creb1a+creb1b+crema+cremb motif

Sorted Z-values of creb1a+creb1b+crema+cremb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_55459037 8.25 ENSDART00000172184
znf569l
zinc finger protein 569, like
chr4_-_65037243 7.51 ENSDART00000170059
si:ch211-283l16.1
si:ch211-283l16.1
chr4_-_63769147 6.79 ENSDART00000189919
znf1098
zinc finger protein 1098
chr4_+_42556555 6.02 ENSDART00000168536
znf1053
zinc finger protein 1053
chr4_+_58016732 5.92 ENSDART00000165777
CT027609.1

chr4_+_63769987 5.70 ENSDART00000168878
znf1048
zinc finger protein 1048
chr4_+_62184754 5.44 ENSDART00000168844
si:dkeyp-35e5.9
si:dkeyp-35e5.9
chr4_-_61650771 5.33 ENSDART00000168593
si:dkey-26i24.1
si:dkey-26i24.1
chr4_-_65036768 5.20 ENSDART00000184455
si:ch211-283l16.1
si:ch211-283l16.1
chr4_-_44872722 5.18 ENSDART00000150621
BX649307.1

chr4_+_64577910 5.15 ENSDART00000128164
si:ch211-223a21.4
si:ch211-223a21.4
chr4_-_61651223 5.13 ENSDART00000172688
si:dkey-26i24.1
si:dkey-26i24.1
chr4_-_64336954 5.07 ENSDART00000157986
znf1147
zinc finger protein 1147
chr4_+_60001731 5.01 ENSDART00000150615
znf1109
zinc finger protein 1109
chr4_-_49952636 4.99 ENSDART00000157941
si:dkey-156k2.3
si:dkey-156k2.3
chr19_-_3056235 4.99 ENSDART00000137020
bop1
block of proliferation 1
chr4_-_45301250 4.98 ENSDART00000181753
si:ch211-162i8.2
si:ch211-162i8.2
chr4_+_33373100 4.96 ENSDART00000150417
znf1090
zinc finger protein 1090
chr4_-_57530817 4.95 ENSDART00000158435
zgc:173702
zgc:173702
chr4_+_45504938 4.95 ENSDART00000145958
si:dkey-256i11.2
si:dkey-256i11.2
chr4_-_59159690 4.94 ENSDART00000164706
znf1149
zinc finger protein 1149
chr4_+_59711338 4.83 ENSDART00000150849
si:dkey-149m13.4
si:dkey-149m13.4
chr9_+_145093 4.81 ENSDART00000162764
rrp1
ribosomal RNA processing 1
chr4_-_41780340 4.79 ENSDART00000167263
znf1049
zinc finger protein 1049
chr20_+_47143900 4.73 ENSDART00000153360
si:dkeyp-104f11.6
si:dkeyp-104f11.6
chr4_-_50544015 4.67 ENSDART00000155155
zgc:174704
zgc:174704
chr22_+_3184500 4.61 ENSDART00000176409
ENSDART00000160604
ftsj3
FtsJ RNA methyltransferase homolog 3
chr4_-_56898328 4.61 ENSDART00000169189
si:dkey-269o24.6
si:dkey-269o24.6
chr4_-_53168673 4.57 ENSDART00000168891
znf1053
zinc finger protein 1053
chr10_-_23099809 4.54 ENSDART00000148333
ENSDART00000079703
ENSDART00000162444
nle1
notchless homolog 1 (Drosophila)
chr4_-_43279775 4.53 ENSDART00000183160
si:dkeyp-53e4.1
si:dkeyp-53e4.1
chr4_+_33461796 4.52 ENSDART00000150445
si:dkey-247i3.1
si:dkey-247i3.1
chr1_+_19764995 4.51 ENSDART00000138276
si:ch211-42i9.8
si:ch211-42i9.8
chr4_+_45504471 4.51 ENSDART00000150399
si:dkey-256i11.2
si:dkey-256i11.2
chr4_+_64577406 4.51 ENSDART00000159754
si:ch211-223a21.4
si:ch211-223a21.4
chr4_-_45301719 4.47 ENSDART00000150282
si:ch211-162i8.2
si:ch211-162i8.2
chr4_-_57001458 4.46 ENSDART00000158660
si:ch211-161m3.1
si:ch211-161m3.1
chr4_-_55040507 4.43 ENSDART00000161731
si:dkey-56m15.3
si:dkey-56m15.3
chr4_-_52621232 4.43 ENSDART00000124451
si:dkeyp-104f11.6
si:dkeyp-104f11.6
chr4_-_64142389 4.35 ENSDART00000172126
BX914205.3

chr4_+_48769555 4.34 ENSDART00000150725
znf1020
zinc finger protein 1020
chr5_+_50869091 4.34 ENSDART00000083294
nol6
nucleolar protein 6 (RNA-associated)
chr4_-_52621665 4.33 ENSDART00000137064
si:dkeyp-104f11.6
si:dkeyp-104f11.6
chr15_+_25635326 4.33 ENSDART00000135409
ENSDART00000162240
ENSDART00000052645
tsr1
TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
chr4_+_30454496 4.32 ENSDART00000164555
si:dkey-199m13.4
si:dkey-199m13.4
chr4_-_43071336 4.32 ENSDART00000150773
znf1072
zinc finger protein 1072
chr4_+_58576146 4.30 ENSDART00000164911
si:ch211-212k5.4
si:ch211-212k5.4
chr4_+_54798291 4.23 ENSDART00000165113
ENSDART00000109624
si:dkeyp-82b4.6
si:dkeyp-82b4.6
chr4_+_62262253 4.23 ENSDART00000166022
si:dkeyp-35e5.10
si:dkeyp-35e5.10
chr4_-_55641422 4.17 ENSDART00000165178
znf1074
zinc finger protein 1074
chr4_+_49073583 4.17 ENSDART00000170022
zgc:173705
zgc:173705
chr4_-_33331681 4.15 ENSDART00000150319
znf1000
zinc finger protein 1000
chr13_-_31370184 4.15 ENSDART00000034829
rrp12
ribosomal RNA processing 12 homolog
chr4_-_70488123 4.13 ENSDART00000169266
si:dkeyp-44b5.5
si:dkeyp-44b5.5
chr4_-_43280244 4.12 ENSDART00000150762
si:dkeyp-53e4.1
si:dkeyp-53e4.1
chr4_+_63818212 4.10 ENSDART00000164929
si:dkey-30f3.2
si:dkey-30f3.2
chr9_+_22929675 4.09 ENSDART00000061299
tsn
translin
chr4_+_52234156 4.09 ENSDART00000161702
si:dkey-16b10.2
si:dkey-16b10.2
chr4_-_57869437 4.07 ENSDART00000170067
zgc:174314
zgc:174314
chr4_-_42294516 4.07 ENSDART00000133558
si:dkey-4e4.1
si:dkey-4e4.1
chr4_+_28418829 4.06 ENSDART00000111603
znf1041
zinc finger protein 1041
chr4_+_59748607 4.03 ENSDART00000108499
znf1068
zinc finger protein 1068
chr4_-_40364432 4.01 ENSDART00000133544
si:dkey-22h13.2
si:dkey-22h13.2
chr4_-_37708661 4.00 ENSDART00000168788
znf1139
zinc finger protein 1139
chr4_-_61920018 3.99 ENSDART00000164832
znf1056
zinc finger protein 1056
chr4_-_64604842 3.97 ENSDART00000169862
znf1099
zinc finger protein 1099
chr4_+_35876704 3.94 ENSDART00000159084
si:dkey-176f19.7
si:dkey-176f19.7
chr4_-_40883162 3.88 ENSDART00000151978
znf1102
zinc finger protein 1102
chr17_-_49481672 3.87 ENSDART00000166394
fcf1
FCF1 rRNA-processing protein
chr4_+_64338860 3.86 ENSDART00000165964
si:ch211-223a21.1
si:ch211-223a21.1
chr4_-_50722304 3.85 ENSDART00000150480
znf1110
zinc finger protein 1110
chr4_-_63769637 3.84 ENSDART00000158757
znf1098
zinc finger protein 1098
chr4_-_67143082 3.83 ENSDART00000162586
CT573263.1

chr4_-_44673017 3.82 ENSDART00000156670
si:dkey-7j22.4
si:dkey-7j22.4
chr15_-_1765098 3.82 ENSDART00000149980
ENSDART00000093074
bud23
BUD23, rRNA methyltransferase and ribosome maturation factor
chr4_+_53183373 3.81 ENSDART00000176617
znf1037
zinc finger protein 1037
chr4_-_40364889 3.80 ENSDART00000151957
si:dkey-22h13.2
si:dkey-22h13.2
chr4_-_28958601 3.78 ENSDART00000111294
zgc:174315
zgc:174315
chr4_-_49720964 3.78 ENSDART00000156103
znf1057
zinc finger protein 1057
chr4_+_41528590 3.78 ENSDART00000164004
znf1094
zinc finger protein 1094
chr4_-_59057046 3.76 ENSDART00000150249
znf1132
zinc finger protein 1132
chr4_-_32179699 3.76 ENSDART00000124106
ENSDART00000158835
si:dkey-72l17.6
si:dkey-72l17.6
chr4_+_68456852 3.74 ENSDART00000165623
znf1146
zinc finger protein 1146
chr4_+_52234600 3.73 ENSDART00000191413
si:dkey-16b10.2
si:dkey-16b10.2
chr4_-_36144500 3.72 ENSDART00000170896
znf992
zinc finger protein 992
chr4_+_59320243 3.72 ENSDART00000150611
znf1084
zinc finger protein 1084
chr4_-_64078341 3.69 ENSDART00000162823
znf1106
zinc finger protein 1106
chr4_-_41825115 3.69 ENSDART00000160196
si:dkey-237m9.1
si:dkey-237m9.1
chr4_+_63818718 3.67 ENSDART00000161177
si:dkey-30f3.2
si:dkey-30f3.2
chr4_+_54899568 3.67 ENSDART00000162786
si:dkey-56m15.8
si:dkey-56m15.8
chr4_-_45433060 3.66 ENSDART00000150524
si:ch211-162i8.4
si:ch211-162i8.4
chr4_+_43408004 3.63 ENSDART00000150476
si:dkeyp-53e4.2
si:dkeyp-53e4.2
chr4_+_36150332 3.62 ENSDART00000161697
znf1116
zinc finger protein 1116
chr4_+_50970601 3.61 ENSDART00000150374
si:dkey-156j15.1
si:dkey-156j15.1
chr4_-_57416684 3.60 ENSDART00000169434
si:dkey-122c11.7
si:dkey-122c11.7
chr5_+_1965296 3.59 ENSDART00000156224
dhx33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr4_+_41227127 3.55 ENSDART00000136445
si:dkey-16p19.5
si:dkey-16p19.5
chr4_-_50158550 3.54 ENSDART00000121664
CR356227.1

chr4_-_30528239 3.54 ENSDART00000169290
znf1052
zinc finger protein 1052
chr4_-_43056627 3.53 ENSDART00000150269
si:dkey-54j5.2
si:dkey-54j5.2
chr4_-_56068511 3.52 ENSDART00000168345
znf1133
zinc finger protein 1133
chr4_-_30362840 3.52 ENSDART00000165929
znf1083
zinc finger protein 1083
chr4_+_44577872 3.47 ENSDART00000157214
si:dkey-7j22.2
si:dkey-7j22.2
chr4_-_69550757 3.46 ENSDART00000168344
znf1101
zinc finger protein 1101
chr4_+_58057168 3.46 ENSDART00000161097
si:dkey-57k17.1
si:dkey-57k17.1
chr4_+_61715860 3.46 ENSDART00000170474
znf1082
zinc finger protein 1082
chr20_-_47270519 3.45 ENSDART00000153329
si:dkeyp-104f11.8
si:dkeyp-104f11.8
chr4_+_40063572 3.43 ENSDART00000146710
BX649521.1

chr4_+_43679421 3.39 ENSDART00000132945
zgc:173705
zgc:173705
chr4_-_32180155 3.38 ENSDART00000164151
si:dkey-72l17.6
si:dkey-72l17.6
chr4_+_29848173 3.37 ENSDART00000150354
znf1121
zinc finger protein 1121
chr4_-_30712160 3.37 ENSDART00000141715
si:dkey-16p19.5
si:dkey-16p19.5
chr6_+_3716666 3.35 ENSDART00000041627
ssb
Sjogren syndrome antigen B (autoantigen La)
chr4_-_57994891 3.33 ENSDART00000168657
znf1097
zinc finger protein 1097
chr20_-_36679233 3.33 ENSDART00000062908
rpl7l1
ribosomal protein L7-like 1
chr4_+_52959625 3.31 ENSDART00000158240
si:dkey-201g16.1
si:dkey-201g16.1
chr3_-_62194512 3.30 ENSDART00000074174
tbl3
transducin (beta)-like 3
chr4_+_28962774 3.30 ENSDART00000150629
si:dkey-23a23.3
si:dkey-23a23.3
chr4_+_59234719 3.28 ENSDART00000170724
ENSDART00000192143
ENSDART00000109914
znf1086
zinc finger protein 1086
chr10_+_23099890 3.28 ENSDART00000135890
LTN1
si:dkey-175g6.5
chr4_-_69615167 3.28 ENSDART00000171108
si:ch211-120c15.3
si:ch211-120c15.3
chr19_+_3056450 3.27 ENSDART00000141324
ENSDART00000082353
hsf1
heat shock transcription factor 1
chr4_-_42074960 3.27 ENSDART00000164406
zgc:174696
zgc:174696
chr4_-_64542903 3.26 ENSDART00000143176
BX936382.1

chr4_-_65090543 3.26 ENSDART00000167888
si:ch211-194h1.2
si:ch211-194h1.2
chr4_-_38259998 3.26 ENSDART00000172389
znf1093
zinc finger protein 1093
chr4_-_69787943 3.26 ENSDART00000166487
znf1081
zinc finger protein 1081
chr4_-_55322519 3.25 ENSDART00000143067
znf998
zinc finger protein 998
chr4_+_61865790 3.24 ENSDART00000166793
si:dkey-146c18.5
si:dkey-146c18.5
chr4_+_64102312 3.23 ENSDART00000157859
znf1103
zinc finger protein 1103
chr4_+_45195202 3.23 ENSDART00000150838
ENSDART00000187011
znf1021
BX649479.1
zinc finger protein 1021

chr4_+_35993527 3.22 ENSDART00000158190
znf1023
zinc finger protein 1023
chr4_+_64147241 3.22 ENSDART00000163509
znf1089
zinc finger protein 1089
chr4_-_55178568 3.22 ENSDART00000165288
znf1039
zinc finger protein 1039
chr4_-_32471434 3.22 ENSDART00000152013
ENSDART00000183621
znf1085
zinc finger protein 1085
chr4_+_41082985 3.22 ENSDART00000164388
si:dkey-16p19.1
si:dkey-16p19.1
chr4_-_39942347 3.21 ENSDART00000124410
znf979
zinc finger protein 979
chr4_-_60356042 3.18 ENSDART00000125171
znf1121
zinc finger protein 1121
chr21_+_3928947 3.17 ENSDART00000149777
setx
senataxin
chr4_+_42175261 3.16 ENSDART00000162193
si:ch211-142b24.2
si:ch211-142b24.2
chr5_+_56277866 3.15 ENSDART00000170610
ENSDART00000028854
ENSDART00000148749
aatf
apoptosis antagonizing transcription factor
chr4_-_30712588 3.13 ENSDART00000142393
si:dkey-16p19.5
si:dkey-16p19.5
chr18_-_5850683 3.13 ENSDART00000082087
nip7
NIP7, nucleolar pre-rRNA processing protein
chr4_+_32566617 3.13 ENSDART00000166485
znf1108
zinc finger protein 1108
chr4_+_37239091 3.12 ENSDART00000172013
znf973
zinc finger protein 973
chr4_+_43678985 3.11 ENSDART00000150395
zgc:173705
zgc:173705
chr4_-_50788075 3.11 ENSDART00000150302
znf1045
zinc finger protein 1045
chr4_+_28442223 3.11 ENSDART00000150879
znf1067
zinc finger protein 1067
chr4_+_69409331 3.11 ENSDART00000159440
si:dkey-246j6.3
si:dkey-246j6.3
chr4_+_41082518 3.10 ENSDART00000151846
si:dkey-16p19.1
si:dkey-16p19.1
chr4_-_45189530 3.02 ENSDART00000150632
BX649516.4

chr5_+_72194444 3.01 ENSDART00000165436
ddx54
DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
chr4_-_56083825 2.99 ENSDART00000157710
znf986
zinc finger protein 986
chr4_-_73488406 2.99 ENSDART00000115002
si:ch73-266f23.1
si:ch73-266f23.1
chr4_-_30422325 2.98 ENSDART00000158444
znf1114
zinc finger protein 1114
chr4_-_69127091 2.97 ENSDART00000136092
si:ch211-209j12.3
si:ch211-209j12.3
chr4_+_61810270 2.95 ENSDART00000158840
CABZ01038376.1

chr4_+_69624049 2.94 ENSDART00000170052
znf1030
zinc finger protein 1030
chr4_-_42171503 2.93 ENSDART00000163798
znf1148
zinc finger protein 1148
chr4_+_38103421 2.93 ENSDART00000164164
znf1016
zinc finger protein 1016
chr15_-_745672 2.91 ENSDART00000155533
im:7143333
im:7143333
chr4_+_65306260 2.91 ENSDART00000167558
si:dkey-14o6.8
si:dkey-14o6.8
chr4_+_69559692 2.89 ENSDART00000164383
znf993
zinc finger protein 993
chr19_-_27339844 2.88 ENSDART00000052358
ENSDART00000148238
ENSDART00000147661
ENSDART00000137346
znrd1
zinc ribbon domain containing 1
chr19_-_27339670 2.87 ENSDART00000139323
znrd1
zinc ribbon domain containing 1
chr4_+_71735828 2.87 ENSDART00000174867
znf1116
zinc finger protein 1116
chr7_-_40657831 2.86 ENSDART00000084153
nom1
nucleolar protein with MIF4G domain 1
chr4_+_65332578 2.85 ENSDART00000170824
znf1108
zinc finger protein 1108
chr4_-_59094319 2.85 ENSDART00000162560
si:dkey-28i19.1
si:dkey-28i19.1
chr4_-_43388943 2.84 ENSDART00000150796
si:dkey-29j8.2
si:dkey-29j8.2
chr4_-_44611273 2.84 ENSDART00000156793
znf1115
zinc finger protein 1115
chr4_+_47385355 2.83 ENSDART00000163413
znf1122
zinc finger protein 1122
chr5_+_69950882 2.83 ENSDART00000097359
dnajc25
DnaJ (Hsp40) homolog, subfamily C , member 25
chr2_+_21605547 2.82 ENSDART00000112014
mplkip
M-phase specific PLK1 interacting protein
chr4_-_60231222 2.82 ENSDART00000169157
znf1080
zinc finger protein 1080
chr4_+_33818711 2.82 ENSDART00000186452
znf1026
zinc finger protein 1026
chr4_+_34657691 2.81 ENSDART00000158655
AL645691.1

chr8_+_21133307 2.81 ENSDART00000056405
magoh
mago homolog, exon junction complex core component
chr4_+_42295479 2.80 ENSDART00000162279
znf1118
zinc finger protein 1118
chr8_+_49065348 2.77 ENSDART00000032277
ddx51
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr4_+_69863019 2.76 ENSDART00000168400
znf1117
zinc finger protein 1117
chr4_+_76466751 2.73 ENSDART00000164709
zgc:153116
zgc:153116
chr4_+_69510337 2.73 ENSDART00000165995
znf1025
zinc finger protein 1025
chr13_-_36141486 2.72 ENSDART00000044115
med6
mediator complex subunit 6
chr4_-_32888436 2.70 ENSDART00000176728
BX324003.2

chr15_+_23722620 2.69 ENSDART00000011447
sae1
SUMO1 activating enzyme subunit 1
chr4_+_33462238 2.68 ENSDART00000111083
si:dkey-247i3.1
si:dkey-247i3.1
chr4_-_33189070 2.67 ENSDART00000150444
CR759833.1

chr4_-_61691066 2.66 ENSDART00000159114
znf1129
zinc finger protein 1129
chr3_-_60027255 2.65 ENSDART00000189252
ENSDART00000154684
recql5
RecQ helicase-like 5
chr4_+_73651053 2.65 ENSDART00000150532
ENSDART00000172536
znf989
zinc finger protein 989
chr4_-_61419027 2.64 ENSDART00000181567
ENSDART00000187397
ENSDART00000180671
ENSDART00000164053
ENSDART00000187395
znf1021
zinc finger protein 1021
chr12_+_36109507 2.64 ENSDART00000175409
map2k6
mitogen-activated protein kinase kinase 6
chr4_+_48802708 2.61 ENSDART00000150313
znf1097
zinc finger protein 1097
chr4_+_69823638 2.59 ENSDART00000165786
znf1087
zinc finger protein 1087
chr3_-_16413606 2.58 ENSDART00000127309
ENSDART00000017172
ENSDART00000136465
eftud2
elongation factor Tu GTP binding domain containing 2
chr2_-_58374842 2.58 ENSDART00000111651
AL954696.1

chr4_+_39055027 2.58 ENSDART00000150397
znf977
zinc finger protein 977
chr23_-_1571682 2.58 ENSDART00000013635
fbxo30b
F-box protein 30b
chr11_-_486532 2.57 ENSDART00000093148
isy1
ISY1 splicing factor homolog

Network of associatons between targets according to the STRING database.

First level regulatory network of creb1a+creb1b+crema+cremb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
1.1 3.3 GO:0000480 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
1.0 3.8 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.9 2.6 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.8 2.5 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.7 12.9 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.7 3.5 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.6 4.3 GO:0000479 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.5 1.6 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.5 3.6 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.5 2.5 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.5 1.5 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.5 1.4 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.5 1.4 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.5 2.3 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.5 3.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.4 1.2 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.4 2.7 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.3 1.3 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.3 1.0 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.3 3.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.3 0.6 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.3 2.6 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.2 2.7 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.2 0.7 GO:0033212 iron assimilation(GO:0033212)
0.2 0.7 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.2 2.0 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.2 4.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 2.4 GO:0006382 adenosine to inosine editing(GO:0006382)
0.2 1.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2 752.4 GO:0006355 regulation of transcription, DNA-templated(GO:0006355)
0.2 1.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 2.9 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.1 0.6 GO:0061015 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.1 19.3 GO:0006364 rRNA processing(GO:0006364)
0.1 1.4 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 1.1 GO:0045117 azole transport(GO:0045117)
0.1 0.5 GO:0006370 7-methylguanosine mRNA capping(GO:0006370) mRNA methylation(GO:0080009)
0.1 1.1 GO:0006611 protein export from nucleus(GO:0006611)
0.1 2.8 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 4.4 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 0.9 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.1 1.4 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.9 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1 1.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 1.0 GO:0007004 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.1 0.8 GO:0030330 DNA damage response, signal transduction by p53 class mediator(GO:0030330)
0.0 2.1 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 2.0 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.4 GO:0036372 opsin transport(GO:0036372)
0.0 1.9 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.0 1.1 GO:0003146 heart jogging(GO:0003146)
0.0 12.5 GO:0008380 RNA splicing(GO:0008380)
0.0 1.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.4 GO:0016926 protein desumoylation(GO:0016926)
0.0 1.5 GO:0006400 tRNA modification(GO:0006400)
0.0 0.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 3.4 GO:0006396 RNA processing(GO:0006396)
0.0 1.8 GO:0043068 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 4.8 GO:0016070 RNA metabolic process(GO:0016070)
0.0 1.4 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.9 GO:0031101 fin regeneration(GO:0031101)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0070545 PeBoW complex(GO:0070545)
1.4 4.3 GO:0032545 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
1.2 13.7 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.7 2.7 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.4 2.7 GO:0070847 core mediator complex(GO:0070847)
0.4 1.5 GO:0070209 ASTRA complex(GO:0070209)
0.3 2.6 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.3 2.6 GO:0032021 NELF complex(GO:0032021)
0.3 2.6 GO:0000974 Prp19 complex(GO:0000974)
0.3 2.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 8.6 GO:0032040 small-subunit processome(GO:0032040)
0.2 0.9 GO:0030896 checkpoint clamp complex(GO:0030896)
0.2 0.6 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 0.7 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 3.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 2.2 GO:0015030 Cajal body(GO:0015030)
0.1 3.3 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 35.3 GO:0005730 nucleolus(GO:0005730)
0.1 1.0 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 0.7 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.8 GO:0035060 brahma complex(GO:0035060)
0.1 1.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 9.5 GO:0016604 nuclear body(GO:0016604)
0.1 386.3 GO:0005634 nucleus(GO:0005634)
0.0 2.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 3.3 GO:0031201 SNARE complex(GO:0031201)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.5 GO:0005882 intermediate filament(GO:0005882)
0.0 0.0 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.6 GO:0034511 U3 snoRNA binding(GO:0034511)
1.5 4.6 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
1.1 3.2 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.9 2.7 GO:0008022 protein C-terminus binding(GO:0008022)
0.9 2.6 GO:0030623 U5 snRNA binding(GO:0030623)
0.8 2.4 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.5 2.4 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.3 1.0 GO:0071532 ankyrin repeat binding(GO:0071532)
0.3 6.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.3 741.9 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.3 2.7 GO:0009378 four-way junction helicase activity(GO:0009378)
0.3 5.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.3 1.8 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 1.5 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 0.7 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.2 3.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.2 2.4 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 1.5 GO:0016421 CoA carboxylase activity(GO:0016421)
0.2 2.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 0.7 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 1.1 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1 1.0 GO:0001032 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.1 1.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 1.0 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 1.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 1.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 1.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.5 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 5.8 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.8 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 4.7 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.1 3.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 3.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.2 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 3.6 GO:0004386 helicase activity(GO:0004386)
0.0 0.6 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.9 GO:0017069 snRNA binding(GO:0017069)
0.0 4.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.2 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 27.5 GO:0003723 RNA binding(GO:0003723)
0.0 3.5 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.9 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 1.3 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.8 GO:0000989 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 3.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 3.3 PID P73PATHWAY p73 transcription factor network
0.0 3.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.2 3.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.0 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 1.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 2.8 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 2.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 2.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 5.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 3.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.7 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.6 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.6 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA