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PRJNA195909:zebrafish embryo and larva development

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Results for ctcf

Z-value: 3.43

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Transcription factors associated with ctcf

Gene Symbol Gene ID Gene Info
ctcf
ENSDARG00000056621 CCCTC-binding factor (zinc finger protein)
ctcf
ENSDARG00000113285 CCCTC-binding factor (zinc finger protein)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ctcfdr11_v1_chr18_+_22287084_222871880.971.6e-05Click!

Activity profile of ctcf motif

Sorted Z-values of ctcf motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_2270069 7.41 ENSDART00000189005
znf740a
zinc finger protein 740a
chr5_+_55984270 6.65 ENSDART00000047358
ENSDART00000138191
fkbp6
FK506 binding protein 6
chr22_-_28777557 6.34 ENSDART00000135214
ENSDART00000131761
ENSDART00000005112
si:dkeyp-34c12.1
si:dkeyp-34c12.1
chr16_-_24642814 5.45 ENSDART00000153987
ENSDART00000154319
fxyd6l
FXYD domain containing ion transport regulator 6 like
chr6_-_8704702 5.42 ENSDART00000064149
nabp1b
nucleic acid binding protein 1b
chr16_+_28881235 4.95 ENSDART00000146525
chtopb
chromatin target of PRMT1b
chr14_-_41468892 4.94 ENSDART00000173099
ENSDART00000003170
mid1ip1l
MID1 interacting protein 1, like
chr8_+_37749263 4.46 ENSDART00000108556
ENSDART00000147942
npm2a
nucleophosmin/nucleoplasmin, 2a
chr25_+_5972690 4.31 ENSDART00000067517
si:ch211-11i22.4
si:ch211-11i22.4
chr21_-_21514176 4.15 ENSDART00000031205
nectin3b
nectin cell adhesion molecule 3b
chr5_+_41496490 4.04 ENSDART00000039369
fancg
Fanconi anemia, complementation group G
chr5_-_31773208 3.90 ENSDART00000137556
ENSDART00000122066
fam102ab
family with sequence similarity 102, member Ab
chr22_-_28777374 3.86 ENSDART00000188206
si:dkeyp-34c12.1
si:dkeyp-34c12.1
chr3_+_37790351 3.83 ENSDART00000151506
si:dkey-260c8.8
si:dkey-260c8.8
chr17_-_51829310 3.77 ENSDART00000154544
numb
numb homolog (Drosophila)
chr13_+_35528607 3.76 ENSDART00000075414
ENSDART00000112947
wdr27
WD repeat domain 27
chr18_+_35229115 3.75 ENSDART00000129624
ENSDART00000184596
tbrg1
transforming growth factor beta regulator 1
chr21_-_19918286 3.70 ENSDART00000180816
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr9_-_34269066 3.66 ENSDART00000059955
ildr1b
immunoglobulin-like domain containing receptor 1b
chr19_-_7070691 3.47 ENSDART00000168755
tapbp.2
TAP binding protein (tapasin), tandem duplicate 2
chr5_-_32396929 3.45 ENSDART00000023977
fbxw2
F-box and WD repeat domain containing 2
chr17_+_7534180 3.44 ENSDART00000187512
shprh
SNF2 histone linker PHD RING helicase
chr9_-_14273652 3.39 ENSDART00000135458
abcb6b
ATP-binding cassette, sub-family B (MDR/TAP), member 6b
chr3_+_14641962 3.22 ENSDART00000091070
zgc:158403
zgc:158403
chr8_+_42917515 3.22 ENSDART00000021715
slc23a2
solute carrier family 23 (ascorbic acid transporter), member 2
chr12_+_19976400 3.21 ENSDART00000153177
mkl2a
MKL/myocardin-like 2a
chr12_-_10567188 3.21 ENSDART00000144283
myof
myoferlin
chr23_-_18057270 3.18 ENSDART00000173385
zgc:92287
zgc:92287
chr5_+_61941610 3.17 ENSDART00000168808
si:dkeyp-117b8.4
si:dkeyp-117b8.4
chr19_+_24068223 3.17 ENSDART00000141351
ENSDART00000100420
pex11b
peroxisomal biogenesis factor 11 beta
chr17_+_7534365 3.15 ENSDART00000157123
shprh
SNF2 histone linker PHD RING helicase
chr25_+_8921425 3.15 ENSDART00000128591
accs
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
chr19_-_7043355 3.12 ENSDART00000104845
tapbp.1
TAP binding protein (tapasin), tandem duplicate 1
chr13_-_35765028 3.12 ENSDART00000157391
erlec1
endoplasmic reticulum lectin 1
chr8_+_13364950 3.11 ENSDART00000159760
slc5a5
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr11_+_25157374 3.09 ENSDART00000019450
trpc4apa
transient receptor potential cation channel, subfamily C, member 4 associated protein a
chr8_-_25569920 3.05 ENSDART00000136869
prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr15_+_31911989 3.03 ENSDART00000111472
brca2
breast cancer 2, early onset
chr8_+_26007988 3.03 ENSDART00000193948
ENSDART00000058100
xpc
xeroderma pigmentosum, complementation group C
chr19_+_1688727 3.02 ENSDART00000115136
ENSDART00000166744
dennd3a
DENN/MADD domain containing 3a
chr14_-_30932373 2.99 ENSDART00000172988
si:zfos-80g12.1
si:zfos-80g12.1
chr22_+_8753092 2.95 ENSDART00000140720
si:dkey-182g1.2
si:dkey-182g1.2
chr1_+_40613297 2.94 ENSDART00000040798
ENSDART00000168067
ENSDART00000130490
naa15b
N(alpha)-acetyltransferase 15, NatA auxiliary subunit b
chr1_+_218524 2.92 ENSDART00000109529
tmco3
transmembrane and coiled-coil domains 3
chr22_+_8753365 2.87 ENSDART00000106086
si:dkey-182g1.2
si:dkey-182g1.2
chr23_-_43595956 2.87 ENSDART00000162186
itchb
itchy E3 ubiquitin protein ligase b
chr1_-_24255149 2.86 ENSDART00000146960
lrba
LPS-responsive vesicle trafficking, beach and anchor containing
chr7_-_71384391 2.84 ENSDART00000112841
ccdc149a
coiled-coil domain containing 149a
chr10_+_2842923 2.83 ENSDART00000181895
ykt6
YKT6 v-SNARE homolog (S. cerevisiae)
chr11_-_25257595 2.82 ENSDART00000123567
snai1a
snail family zinc finger 1a
chr12_-_7639120 2.78 ENSDART00000126712
ENSDART00000126219
ccdc6b
coiled-coil domain containing 6b
chr6_-_42388608 2.77 ENSDART00000049425
sec61a1l
Sec61 translocon alpha 1 subunit, like
chr8_-_51954562 2.76 ENSDART00000132527
ENSDART00000057315
cep78
centrosomal protein 78
chr12_+_23991639 2.75 ENSDART00000003143
psme4b
proteasome activator subunit 4b
chr10_+_41939963 2.70 ENSDART00000126248
tmem120b
transmembrane protein 120B
chr16_+_40340523 2.69 ENSDART00000102571
mettl6
methyltransferase like 6
chr12_-_3077395 2.67 ENSDART00000002867
ENSDART00000126315
rfng
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr12_-_48374728 2.67 ENSDART00000153403
ENSDART00000188117
dnajb12b
DnaJ (Hsp40) homolog, subfamily B, member 12b
chr6_+_60125033 2.67 ENSDART00000148557
ENSDART00000008224
aurka
aurora kinase A
chr24_-_38644937 2.66 ENSDART00000170194
slc6a16b
solute carrier family 6, member 16b
chr10_-_32494499 2.65 ENSDART00000129395
uvrag
UV radiation resistance associated gene
chr12_+_31783066 2.64 ENSDART00000105584
lrrc59
leucine rich repeat containing 59
chr5_-_29514689 2.60 ENSDART00000126018
ENSDART00000125175
ehmt1a
euchromatic histone-lysine N-methyltransferase 1a
chr17_-_10498347 2.60 ENSDART00000171324
mipol1
mirror-image polydactyly 1
chr19_+_20785724 2.60 ENSDART00000038942
adnp2b
ADNP homeobox 2b
chr10_-_32494304 2.59 ENSDART00000028161
uvrag
UV radiation resistance associated gene
chr2_-_9744081 2.58 ENSDART00000097732
dvl3a
dishevelled segment polarity protein 3a
chr9_-_11263228 2.57 ENSDART00000113847
chpfa
chondroitin polymerizing factor a
chr1_+_45839927 2.54 ENSDART00000148086
ENSDART00000180413
ENSDART00000048191
ENSDART00000179047
map2k7
mitogen-activated protein kinase kinase 7
chr24_-_13349802 2.49 ENSDART00000164729
terf1
telomeric repeat binding factor (NIMA-interacting) 1
chr10_-_28118035 2.48 ENSDART00000190836
ENSDART00000088852
med13a
mediator complex subunit 13a
chr13_-_36761379 2.47 ENSDART00000131534
ENSDART00000029824
map4k5
mitogen-activated protein kinase kinase kinase kinase 5
chr8_-_34427364 2.46 ENSDART00000112854
ENSDART00000161282
ENSDART00000113230
gapvd1
GTPase activating protein and VPS9 domains 1
chr10_-_28117740 2.45 ENSDART00000134491
med13a
mediator complex subunit 13a
chr2_-_26596794 2.41 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr15_-_43978141 2.38 ENSDART00000041249
chordc1a
cysteine and histidine-rich domain (CHORD) containing 1a
chr24_+_39027481 2.37 ENSDART00000085565
capn15
calpain 15
chr22_+_14836040 2.37 ENSDART00000180951
gtpbp1l
GTP binding protein 1, like
chr12_+_23991276 2.37 ENSDART00000153136
psme4b
proteasome activator subunit 4b
chr20_+_49895220 2.36 ENSDART00000097865
ints9
integrator complex subunit 9
chr17_+_30894431 2.33 ENSDART00000127996
degs2
delta(4)-desaturase, sphingolipid 2
chr23_+_24501918 2.32 ENSDART00000078824
szrd1
SUZ RNA binding domain containing 1
chr16_-_5873866 2.32 ENSDART00000136936
trak1a
trafficking protein, kinesin binding 1a
chr1_+_41690402 2.32 ENSDART00000177298
fbxo41
F-box protein 41
chr1_+_58922027 2.30 ENSDART00000159479
trip10b
thyroid hormone receptor interactor 10b
chr7_-_9674073 2.26 ENSDART00000187902
lrrk1
leucine-rich repeat kinase 1
chr9_-_41507712 2.25 ENSDART00000135821
mfsd6b
major facilitator superfamily domain containing 6b
chr20_+_26002534 2.24 ENSDART00000147845
nrbp1
nuclear receptor binding protein 1
chr6_+_38773376 2.23 ENSDART00000078128
ENSDART00000184053
ube3a
ubiquitin protein ligase E3A
chr10_+_33626344 2.23 ENSDART00000109563
b3glctb
beta 3-glucosyltransferase b
chr3_+_25849560 2.21 ENSDART00000007119
mfsd6l
major facilitator superfamily domain containing 6-like
chr1_+_26676758 2.20 ENSDART00000152299
si:dkey-25o16.4
si:dkey-25o16.4
chr12_+_27589607 2.20 ENSDART00000066288
spata20
spermatogenesis associated 20
chr3_+_36671585 2.19 ENSDART00000159033
nde1
nudE neurodevelopment protein 1
chr2_+_43204919 2.19 ENSDART00000160077
ENSDART00000018729
ENSDART00000129134
ENSDART00000056402
pard3ab
par-3 family cell polarity regulator alpha, b
chr17_-_50063437 2.18 ENSDART00000187943
zgc:113886
zgc:113886
chr3_+_22432069 2.15 ENSDART00000123054
wnk4b
WNK lysine deficient protein kinase 4b
chr20_-_54192130 2.13 ENSDART00000020834
CABZ01111496.1

chr25_-_7650335 2.09 ENSDART00000089034
myo5ab
myosin VAb
chr7_+_34236238 2.05 ENSDART00000052474
tipin
timeless interacting protein
chr24_-_13349464 2.05 ENSDART00000134482
ENSDART00000139212
terf1
telomeric repeat binding factor (NIMA-interacting) 1
chr17_+_33158350 2.04 ENSDART00000104476
snx9a
sorting nexin 9a
chr1_-_53918839 2.03 ENSDART00000032552
taf5l
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr22_-_20403194 2.03 ENSDART00000010048
map2k2a
mitogen-activated protein kinase kinase 2a
chr1_+_22851261 2.03 ENSDART00000193925
gtf2e2
general transcription factor IIE, polypeptide 2, beta
chr10_-_35186310 2.03 ENSDART00000127805
pom121
POM121 transmembrane nucleoporin
chr8_+_2757821 2.01 ENSDART00000051403
ENSDART00000160551
sh3glb2a
SH3-domain GRB2-like endophilin B2a
chr8_-_11202378 2.01 ENSDART00000147817
ENSDART00000174039
fam208b
family with sequence similarity 208, member B
chr5_+_55934129 1.98 ENSDART00000050969
tmem150ab
transmembrane protein 150Ab
chr9_-_1200187 1.96 ENSDART00000158760
ino80da
INO80 complex subunit Da
chr13_+_13033424 1.95 ENSDART00000159441
letm1
leucine zipper-EF-hand containing transmembrane protein 1
chr6_-_27139396 1.95 ENSDART00000055848
zgc:103559
zgc:103559
chr3_+_40407352 1.94 ENSDART00000155112
tnrc18
trinucleotide repeat containing 18
chr12_-_31726748 1.93 ENSDART00000153174
srsf2a
serine/arginine-rich splicing factor 2a
chr16_+_40340222 1.93 ENSDART00000190631
mettl6
methyltransferase like 6
chr24_-_17400143 1.92 ENSDART00000134947
cul1b
cullin 1b
chr20_+_38458084 1.92 ENSDART00000020153
ENSDART00000135912
coq8a
coenzyme Q8A
chr18_+_27001115 1.91 ENSDART00000133547
pik3c2a
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
chr15_-_26887028 1.91 ENSDART00000156292
si:dkey-243i1.1
si:dkey-243i1.1
chr2_+_23701613 1.91 ENSDART00000047073
oxsr1a
oxidative stress responsive 1a
chr15_-_4967302 1.85 ENSDART00000101992
lipt2
lipoyl(octanoyl) transferase 2
chr21_+_6114709 1.85 ENSDART00000065858
fpgs
folylpolyglutamate synthase
chr21_+_6114305 1.84 ENSDART00000141607
fpgs
folylpolyglutamate synthase
chr25_-_13871118 1.84 ENSDART00000160866
cry2
cryptochrome circadian clock 2
chr7_-_58251527 1.81 ENSDART00000114008
ENSDART00000185189
unm_hu7910
un-named hu7910
chr5_-_1869982 1.81 ENSDART00000055878
rcl1
RNA terminal phosphate cyclase-like 1
chr1_+_21937201 1.80 ENSDART00000087729
kdm4c
lysine (K)-specific demethylase 4C
chr2_+_3823813 1.80 ENSDART00000103596
ENSDART00000161880
ENSDART00000185408
npc1
Niemann-Pick disease, type C1
chr2_+_22659787 1.79 ENSDART00000043956
zgc:161973
zgc:161973
chr21_-_21824285 1.77 ENSDART00000030984
wdr73
WD repeat domain 73
chr11_+_2596667 1.73 ENSDART00000175330
dnajc14
DnaJ (Hsp40) homolog, subfamily C, member 14
chr1_-_45577980 1.72 ENSDART00000160961
atf7ip
activating transcription factor 7 interacting protein
chr1_+_49878000 1.70 ENSDART00000047876
lef1
lymphoid enhancer-binding factor 1
chr8_+_19621731 1.69 ENSDART00000144667
slc35a3a
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr14_+_31473866 1.69 ENSDART00000173088
ccdc160
coiled-coil domain containing 160
chr8_+_19621511 1.68 ENSDART00000017128
slc35a3a
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr5_-_26764298 1.68 ENSDART00000189373
rnf181
ring finger protein 181
chr14_-_45595711 1.67 ENSDART00000074038
scyl1
SCY1-like, kinase-like 1
chr21_+_25120546 1.67 ENSDART00000149507
ddx10
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr11_+_22623284 1.66 ENSDART00000111850
si:ch211-86h15.1
si:ch211-86h15.1
chr19_-_3886991 1.66 ENSDART00000162085
thrap3b
thyroid hormone receptor associated protein 3b
chr6_+_8153813 1.65 ENSDART00000192436
nfil3-3
nuclear factor, interleukin 3 regulated, member 3
chr24_+_26276805 1.65 ENSDART00000089749
adipoqa
adiponectin, C1Q and collagen domain containing, a
chr2_+_36606019 1.64 ENSDART00000098415
ing5b
inhibitor of growth family, member 5b
chr15_-_4967490 1.62 ENSDART00000180551
lipt2
lipoyl(octanoyl) transferase 2
chr24_+_26329018 1.58 ENSDART00000145752
mynn
myoneurin
chr18_+_27000850 1.58 ENSDART00000188906
ENSDART00000086131
pik3c2a
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
chr2_+_11028923 1.56 ENSDART00000076725
acot11a
acyl-CoA thioesterase 11a
chr3_+_31093455 1.55 ENSDART00000153074
si:dkey-66i24.9
si:dkey-66i24.9
chr6_-_35046735 1.55 ENSDART00000143649
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr7_+_66634167 1.53 ENSDART00000027616
eif4g2a
eukaryotic translation initiation factor 4, gamma 2a
chr19_+_4139065 1.53 ENSDART00000172524
si:dkey-218f9.10
si:dkey-218f9.10
chr16_-_32672883 1.52 ENSDART00000124515
ENSDART00000190920
ENSDART00000188776
pnisr
PNN-interacting serine/arginine-rich protein
chr7_+_29080684 1.51 ENSDART00000173709
ENSDART00000173576
acd
ACD, shelterin complex subunit and telomerase recruitment factor
chr12_-_18898413 1.50 ENSDART00000181281
ENSDART00000121866
desi1b
desumoylating isopeptidase 1b
chr24_+_26328787 1.48 ENSDART00000003884
mynn
myoneurin
chr13_+_13033837 1.47 ENSDART00000079558
letm1
leucine zipper-EF-hand containing transmembrane protein 1
chr13_-_37600600 1.46 ENSDART00000003888
snapc1b
small nuclear RNA activating complex, polypeptide 1b
chr6_+_55819038 1.44 ENSDART00000108786
si:ch211-81n22.1
si:ch211-81n22.1
chr8_+_21437908 1.43 ENSDART00000142758
si:dkey-163f12.10
si:dkey-163f12.10
chr16_-_8132742 1.43 ENSDART00000104323
snrka
SNF related kinase a
chr6_-_1591002 1.42 ENSDART00000087039
zgc:123305
zgc:123305
chr10_-_25716841 1.41 ENSDART00000140483
ENSDART00000125665
ENSDART00000181678
scaf4a
SR-related CTD-associated factor 4a
chr8_+_47099033 1.39 ENSDART00000142979
arhgef16
Rho guanine nucleotide exchange factor (GEF) 16
chr22_+_737211 1.37 ENSDART00000017305
znf76
zinc finger protein 76
chr9_-_30243393 1.36 ENSDART00000089539
si:dkey-100n23.3
si:dkey-100n23.3
chr9_+_35832294 1.35 ENSDART00000130549
ENSDART00000122169
si:dkey-67c22.2
si:dkey-67c22.2
chr15_-_17406056 1.33 ENSDART00000146735
tubd1
tubulin, delta 1
chr2_-_25140022 1.33 ENSDART00000134543
nceh1a
neutral cholesterol ester hydrolase 1a
chr9_+_22929675 1.32 ENSDART00000061299
tsn
translin
chr8_-_11324143 1.32 ENSDART00000008215
pip5k1bb
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr5_+_58687541 1.31 ENSDART00000083015
ENSDART00000181902
ccdc84
coiled-coil domain containing 84
chr7_-_34256374 1.29 ENSDART00000075176
dis3l
DIS3 like exosome 3'-5' exoribonuclease
chr20_-_29864390 1.29 ENSDART00000161834
ENSDART00000132278
rnf144ab
ring finger protein 144ab
chr1_+_35194454 1.28 ENSDART00000165389
sc:d189
sc:d189
chr9_-_29643628 1.28 ENSDART00000101177
spryd7b
SPRY domain containing 7b
chr15_+_17441734 1.27 ENSDART00000153729
snx19b
sorting nexin 19b
chr12_-_33582382 1.27 ENSDART00000009794
ENSDART00000136617
tdrkh
tudor and KH domain containing
chr6_+_11681011 1.26 ENSDART00000151447
ENSDART00000151618
calcrlb
calcitonin receptor-like b
chr17_+_22577472 1.26 ENSDART00000045099
yipf4
Yip1 domain family, member 4
chr22_-_3595439 1.24 ENSDART00000083308
ptprsa
protein tyrosine phosphatase, receptor type, s, a
chr5_+_31036911 1.21 ENSDART00000141463
ENSDART00000162121
zzef1
zinc finger, ZZ-type with EF hand domain 1
chr8_-_38317914 1.18 ENSDART00000125920
pdlim2
PDZ and LIM domain 2 (mystique)
chr14_-_31715373 1.17 ENSDART00000127303
ENSDART00000173274
ENSDART00000173435
ENSDART00000172876
ENSDART00000173036
map7d3
MAP7 domain containing 3
chr5_+_32076109 1.16 ENSDART00000051357
ENSDART00000144510
zmat5
zinc finger, matrin-type 5
chr20_+_46699021 1.16 ENSDART00000167398
ENSDART00000029894
wdr26b
WD repeat domain 26b
chr6_+_21993613 1.15 ENSDART00000160750
ENSDART00000083070
thumpd3
THUMP domain containing 3
chr1_+_34763539 1.14 ENSDART00000077725
ENSDART00000113808
zgc:172122
zgc:172122
chr22_+_35131890 1.14 ENSDART00000003303
ENSDART00000130581
rnf13
ring finger protein 13
chr13_+_9819194 1.14 ENSDART00000091595
fam45a
family with sequence similarity 45, member A
chr20_-_43079478 1.11 ENSDART00000060982
snx9b
sorting nexin 9b
chr23_-_19486571 1.11 ENSDART00000009092
fam208ab
family with sequence similarity 208, member Ab
chr25_+_19733704 1.11 ENSDART00000145334
ENSDART00000138946
ENSDART00000138851
zgc:101783
zgc:101783
chr12_-_17492852 1.11 ENSDART00000012421
ENSDART00000138766
ENSDART00000130735
minpp1b
multiple inositol-polyphosphate phosphatase 1b
chr12_-_999762 1.09 ENSDART00000127003
ENSDART00000084076
ENSDART00000152425
mettl9
methyltransferase like 9
chr4_-_18512550 1.07 ENSDART00000045639
rint1
RAD50 interactor 1
chr15_+_22435460 1.05 ENSDART00000031976
tmem136a
transmembrane protein 136a
chr1_+_2301961 1.04 ENSDART00000108919
ENSDART00000143361
ENSDART00000142944
farp1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr15_+_25681044 1.04 ENSDART00000077853
hic1
hypermethylated in cancer 1
chr18_+_907266 1.04 ENSDART00000171729
pkma
pyruvate kinase M1/2a

Network of associatons between targets according to the STRING database.

First level regulatory network of ctcf

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
1.2 3.5 GO:2000376 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
1.1 3.4 GO:0034214 protein hexamerization(GO:0034214)
1.1 3.2 GO:0015882 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.9 3.7 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.9 2.7 GO:0000212 meiotic spindle organization(GO:0000212)
0.9 5.1 GO:0035092 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.6 1.9 GO:0000256 allantoin catabolic process(GO:0000256) purine nucleobase catabolic process(GO:0006145)
0.6 2.3 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.5 2.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.5 0.5 GO:0006884 cell volume homeostasis(GO:0006884)
0.5 3.2 GO:0016559 peroxisome fission(GO:0016559)
0.5 1.5 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.4 2.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.4 2.2 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.4 3.0 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.4 2.9 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4 2.0 GO:0043111 replication fork arrest(GO:0043111)
0.4 2.8 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.4 6.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.4 2.3 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.4 2.6 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.4 1.5 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.4 2.2 GO:0051299 mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299)
0.4 1.8 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.4 1.8 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.3 5.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.3 1.7 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.3 3.4 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.3 0.9 GO:0071896 protein localization to adherens junction(GO:0071896)
0.3 0.9 GO:0046324 regulation of glucose import(GO:0046324)
0.3 4.5 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.3 3.1 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.3 0.8 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.3 2.7 GO:0045444 fat cell differentiation(GO:0045444)
0.2 3.7 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.2 2.7 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.2 1.7 GO:0061635 regulation of protein complex stability(GO:0061635)
0.2 0.7 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.2 0.9 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.2 3.2 GO:0007530 sex determination(GO:0007530)
0.2 3.4 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.2 5.0 GO:0007286 spermatid development(GO:0007286)
0.2 3.0 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 0.6 GO:0006089 lactate metabolic process(GO:0006089)
0.2 1.0 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.2 0.9 GO:0043420 anthranilate metabolic process(GO:0043420)
0.2 1.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.2 1.1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.2 2.3 GO:0034311 diol metabolic process(GO:0034311)
0.2 2.6 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 5.1 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 1.8 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.4 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1 2.8 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 1.7 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.4 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 1.8 GO:0000479 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1 0.5 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 3.2 GO:0007520 myoblast fusion(GO:0007520)
0.1 4.0 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 2.7 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.1 1.6 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 5.4 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 0.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 1.0 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.6 GO:1901910 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 4.9 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.1 2.4 GO:0006298 mismatch repair(GO:0006298)
0.1 2.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 1.3 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 3.1 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 3.8 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 2.0 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 5.2 GO:0010212 response to ionizing radiation(GO:0010212)
0.1 2.8 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.1 1.0 GO:0051654 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) establishment of mitochondrion localization(GO:0051654)
0.1 4.3 GO:0051298 centrosome duplication(GO:0051298)
0.1 1.2 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 1.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 2.4 GO:0016180 snRNA processing(GO:0016180)
0.1 1.6 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.1 1.4 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 1.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 0.6 GO:1901998 toxin transport(GO:1901998)
0.1 0.3 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 6.6 GO:0006334 nucleosome assembly(GO:0006334)
0.1 2.6 GO:0051057 positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.1 0.8 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.1 2.0 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 3.2 GO:0000281 mitotic cytokinesis(GO:0000281)
0.1 0.9 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 2.5 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 2.4 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 0.4 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 6.2 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.3 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.7 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.9 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 2.6 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.7 GO:0015693 magnesium ion transport(GO:0015693)
0.0 2.1 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 1.0 GO:0090148 membrane fission(GO:0090148)
0.0 1.0 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.4 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 2.5 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 0.5 GO:0046660 female sex differentiation(GO:0046660)
0.0 1.8 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 1.2 GO:0030488 tRNA methylation(GO:0030488)
0.0 3.2 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 3.1 GO:0098661 inorganic anion transmembrane transport(GO:0098661)
0.0 4.6 GO:0032259 methylation(GO:0032259)
0.0 1.0 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 0.8 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 1.5 GO:0006414 translational elongation(GO:0006414)
0.0 0.8 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.8 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.4 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.3 GO:0010821 regulation of mitochondrion organization(GO:0010821)
0.0 2.1 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.5 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.4 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 1.5 GO:0070646 protein modification by small protein removal(GO:0070646)
0.0 1.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 1.2 GO:0006413 translational initiation(GO:0006413)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.9 5.4 GO:0070876 SOSS complex(GO:0070876)
0.6 2.9 GO:0031415 NatA complex(GO:0031415)
0.6 2.8 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.5 1.5 GO:0019185 snRNA-activating protein complex(GO:0019185)
0.5 2.8 GO:0005784 Sec61 translocon complex(GO:0005784)
0.4 2.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.4 3.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.4 2.0 GO:0031298 replication fork protection complex(GO:0031298)
0.4 3.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.4 3.0 GO:0061700 GATOR2 complex(GO:0061700)
0.3 2.0 GO:0030914 STAGA complex(GO:0030914)
0.3 3.0 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.3 6.0 GO:0000784 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.3 3.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 3.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 0.8 GO:0070209 ASTRA complex(GO:0070209)
0.2 0.5 GO:0034709 methylosome(GO:0034709)
0.2 0.5 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 6.6 GO:0016592 mediator complex(GO:0016592)
0.1 1.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 2.4 GO:0032039 integrator complex(GO:0032039)
0.1 0.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.6 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 6.7 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 0.3 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.7 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.7 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 1.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 3.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 2.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.5 GO:0089701 U2AF(GO:0089701)
0.1 0.8 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.9 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 5.1 GO:0000786 nucleosome(GO:0000786)
0.0 2.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.7 GO:0008305 integrin complex(GO:0008305)
0.0 0.5 GO:0044545 NSL complex(GO:0044545)
0.0 1.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 3.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 7.6 GO:0005819 spindle(GO:0005819)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0030904 retromer complex(GO:0030904)
0.0 3.5 GO:0016607 nuclear speck(GO:0016607)
0.0 2.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 4.2 GO:0043296 apical junction complex(GO:0043296)
0.0 1.8 GO:0005643 nuclear pore(GO:0005643)
0.0 8.1 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 1.2 GO:0031941 filamentous actin(GO:0031941)
0.0 0.9 GO:0035869 ciliary transition zone(GO:0035869)
0.0 3.0 GO:0016459 myosin complex(GO:0016459)
0.0 1.3 GO:0005814 centriole(GO:0005814)
0.0 1.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 3.7 GO:0000323 lytic vacuole(GO:0000323)
0.0 1.6 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.0 GO:0005741 mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:0071532 ankyrin repeat binding(GO:0071532)
1.2 3.5 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.9 3.4 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.8 2.3 GO:0001635 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.7 2.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.7 2.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.5 5.1 GO:0016504 peptidase activator activity(GO:0016504)
0.5 2.5 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.5 1.9 GO:0050897 cobalt ion binding(GO:0050897)
0.5 1.8 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.4 3.0 GO:0070728 leucine binding(GO:0070728)
0.4 3.4 GO:0015232 heme transporter activity(GO:0015232)
0.4 2.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.4 2.7 GO:0035173 histone kinase activity(GO:0035173)
0.3 3.4 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.3 1.6 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.3 2.6 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.3 0.8 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.3 1.9 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.3 1.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.2 3.7 GO:2001069 glycogen binding(GO:2001069)
0.2 2.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 5.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 2.8 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.2 2.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 2.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 1.0 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 1.4 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 2.9 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.1 2.6 GO:0002039 p53 binding(GO:0002039)
0.1 0.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 2.2 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 2.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.9 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 3.7 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 6.0 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 2.3 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.6 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 2.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.7 GO:0008301 DNA binding, bending(GO:0008301)
0.1 2.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 3.8 GO:0003684 damaged DNA binding(GO:0003684)
0.1 0.7 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 0.9 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.1 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.8 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 2.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 0.6 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.1 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 2.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.3 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.1 1.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.6 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 1.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 2.6 GO:0005109 frizzled binding(GO:0005109)
0.1 1.2 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 1.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 19.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 3.1 GO:0019902 phosphatase binding(GO:0019902)
0.0 2.8 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 2.8 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 3.8 GO:0045296 cadherin binding(GO:0045296)
0.0 3.1 GO:0015296 anion:cation symporter activity(GO:0015296)
0.0 2.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.3 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 2.5 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 1.8 GO:0071949 FAD binding(GO:0071949)
0.0 0.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 11.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 4.2 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.9 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.7 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 1.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 2.2 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 5.1 GO:0000149 SNARE binding(GO:0000149)
0.0 2.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.7 GO:0003724 RNA helicase activity(GO:0003724)
0.0 3.0 GO:0042393 histone binding(GO:0042393)
0.0 4.6 GO:0008168 methyltransferase activity(GO:0008168)
0.0 6.6 GO:0000989 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 1.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 2.9 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 8.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 7.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 1.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 2.7 PID AURORA A PATHWAY Aurora A signaling
0.1 3.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 2.0 PID ATR PATHWAY ATR signaling pathway
0.1 3.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 3.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 3.5 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 3.7 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 0.9 PID ATM PATHWAY ATM pathway
0.1 2.5 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.0 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.4 6.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.4 7.1 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.3 3.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.3 3.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 3.8 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 0.9 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 2.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 6.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 3.0 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 2.5 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 4.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 2.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 2.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 3.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 0.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.8 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.9 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.8 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 2.3 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 1.7 REACTOME TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION Genes involved in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
0.0 0.5 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 2.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import