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PRJNA195909:zebrafish embryo and larva development

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Results for cux2b

Z-value: 0.70

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Transcription factors associated with cux2b

Gene Symbol Gene ID Gene Info
cux2b
ENSDARG00000086345 cut-like homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cux2bdr11_v1_chr8_-_4100365_41003650.472.0e-01Click!

Activity profile of cux2b motif

Sorted Z-values of cux2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_77135340 1.35 ENSDART00000180581
ENSDART00000179901
CU467646.7

chr19_-_48039400 1.33 ENSDART00000166748
ENSDART00000165921
csf3b
colony stimulating factor 3 (granulocyte) b
chr17_-_2578026 0.99 ENSDART00000065821
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr17_-_2584423 0.86 ENSDART00000013506
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr17_-_2590222 0.79 ENSDART00000185711
CR759892.1

chr17_-_2573021 0.77 ENSDART00000074181
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr7_+_30626378 0.75 ENSDART00000173533
ENSDART00000052541
ccnb2
cyclin B2
chr4_-_77140030 0.72 ENSDART00000174332
ENSDART00000190394
ENSDART00000189208
CU467646.5
CU467646.7


chr4_-_77135076 0.72 ENSDART00000174184
zgc:173770
zgc:173770
chr6_+_54496808 0.70 ENSDART00000156263
si:ch211-233f11.5
si:ch211-233f11.5
chr4_-_77130289 0.70 ENSDART00000174380
CU467646.7

chr4_-_77125693 0.69 ENSDART00000174256
CU467646.3

chr6_+_3373665 0.66 ENSDART00000134133
st3gal3a
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr10_-_21545091 0.66 ENSDART00000029122
ENSDART00000132207
zgc:165539
zgc:165539
chr23_+_32101202 0.65 ENSDART00000000992
zgc:56699
zgc:56699
chr25_+_22320738 0.63 ENSDART00000073566
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr2_+_42871831 0.63 ENSDART00000171393
efr3a
EFR3 homolog A (S. cerevisiae)
chr2_-_15324837 0.63 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr18_+_20560616 0.62 ENSDART00000136710
ENSDART00000151974
ENSDART00000121699
ENSDART00000040074
wee2
WEE1 homolog 2 (S. pombe)
chr15_-_931815 0.57 ENSDART00000106627
ENSDART00000102239
ENSDART00000184754
ENSDART00000186733
zgc:162936
zgc:162936
chr12_-_13730501 0.56 ENSDART00000152370
foxh1
forkhead box H1
chr6_-_17999776 0.53 ENSDART00000183048
ENSDART00000181577
ENSDART00000170597
rptor
regulatory associated protein of MTOR, complex 1
chr10_-_42898220 0.53 ENSDART00000099270
CU326366.2

chr25_+_2645488 0.52 ENSDART00000113032
adck2
aarF domain containing kinase 2
chr13_-_18695289 0.50 ENSDART00000176809
sfxn3
sideroflexin 3
chr12_+_16953415 0.49 ENSDART00000020824
pank1b
pantothenate kinase 1b
chr23_+_43684494 0.49 ENSDART00000149878
otud4
OTU deubiquitinase 4
chr7_+_30933867 0.49 ENSDART00000156325
tjp1a
tight junction protein 1a
chr14_-_899170 0.49 ENSDART00000165211
ENSDART00000031992
rgs14a
regulator of G protein signaling 14a
chr21_+_20391978 0.48 ENSDART00000180817
si:dkey-30k6.5
si:dkey-30k6.5
chr25_+_21517551 0.48 ENSDART00000155832
si:dkey-81e3.2
si:dkey-81e3.2
chr19_-_18130567 0.47 ENSDART00000190659
ENSDART00000022803
snx10a
sorting nexin 10a
chr8_+_41038141 0.46 ENSDART00000075620
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr16_+_29509133 0.44 ENSDART00000112116
ctss2.1
cathepsin S, ortholog2, tandem duplicate 1
chr10_+_33393829 0.44 ENSDART00000163458
ENSDART00000115379
zgc:153345
zgc:153345
chr19_+_28291062 0.43 ENSDART00000163382
lpcat1
lysophosphatidylcholine acyltransferase 1
chr23_+_38171186 0.43 ENSDART00000148188
zgc:112994
zgc:112994
chr15_-_44601331 0.43 ENSDART00000161514
zgc:165508
zgc:165508
chr7_+_32695954 0.43 ENSDART00000184425
slc39a13
solute carrier family 39 (zinc transporter), member 13
chr19_+_28291376 0.43 ENSDART00000139433
ENSDART00000103855
lpcat1
lysophosphatidylcholine acyltransferase 1
chr15_+_29472065 0.41 ENSDART00000154343
gdpd5b
glycerophosphodiester phosphodiesterase domain containing 5b
chr5_+_37729207 0.41 ENSDART00000184378
cdc42ep2
CDC42 effector protein (Rho GTPase binding) 2
chr9_+_22780901 0.41 ENSDART00000110992
ENSDART00000143972
rif1
replication timing regulatory factor 1
chr22_+_26665422 0.41 ENSDART00000164994
adcy9
adenylate cyclase 9
chr8_-_53044300 0.40 ENSDART00000191653
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr18_-_15610856 0.40 ENSDART00000099849
arntl2
aryl hydrocarbon receptor nuclear translocator-like 2
chr24_-_33366188 0.40 ENSDART00000074161
slc4a2b
solute carrier family 4 (anion exchanger), member 2b
chr2_+_23007675 0.40 ENSDART00000163649
mknk2a
MAP kinase interacting serine/threonine kinase 2a
chr21_+_3901775 0.39 ENSDART00000053609
dolpp1
dolichyldiphosphatase 1
chr25_-_37262220 0.38 ENSDART00000153789
ENSDART00000155182
rfwd3
ring finger and WD repeat domain 3
chr19_-_874888 0.37 ENSDART00000007206
eomesa
eomesodermin homolog a
chr2_+_24936766 0.37 ENSDART00000025962
gyg1a
glycogenin 1a
chr23_-_24542952 0.37 ENSDART00000088777
atp13a2
ATPase 13A2
chr22_-_37797695 0.37 ENSDART00000085931
ENSDART00000185443
acap2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr13_-_27354003 0.37 ENSDART00000101479
ENSDART00000044652
ddx43
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
chr22_-_6420239 0.37 ENSDART00000148385
zgc:171699
zgc:171699
chr9_+_55455801 0.37 ENSDART00000144757
ENSDART00000186543
mxra5b
matrix-remodelling associated 5b
chr3_-_30488063 0.36 ENSDART00000055393
ENSDART00000151367
med25
mediator complex subunit 25
chr9_+_12907574 0.36 ENSDART00000102348
si:dkey-230p4.1
si:dkey-230p4.1
chr25_-_37314700 0.35 ENSDART00000017807
igl4v8
immunoglobulin light 4 variable 8
chr17_+_24318753 0.35 ENSDART00000064083
otx1
orthodenticle homeobox 1
chr18_+_44630415 0.35 ENSDART00000098540
bicra
BRD4 interacting chromatin remodeling complex associated protein
chr19_+_13994563 0.35 ENSDART00000164696
tmem222b
transmembrane protein 222b
chr19_-_425145 0.35 ENSDART00000164905
dus3l
dihydrouridine synthase 3-like (S. cerevisiae)
chr11_-_42396302 0.35 ENSDART00000165624
slmapa
sarcolemma associated protein a
chr5_+_29851433 0.35 ENSDART00000143434
ubash3ba
ubiquitin associated and SH3 domain containing Ba
chr16_-_46393154 0.35 ENSDART00000132154
si:ch73-59c19.1
si:ch73-59c19.1
chr7_+_41812817 0.35 ENSDART00000174165
orc6
origin recognition complex, subunit 6
chr13_-_9442942 0.35 ENSDART00000138833
grxcr1
glutaredoxin, cysteine rich 1
chr20_-_33966148 0.34 ENSDART00000148111
selp
selectin P
chr11_+_5817202 0.34 ENSDART00000126084
ctdspl3
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 3
chr8_+_11325310 0.34 ENSDART00000142577
fxn
frataxin
chr19_-_7033636 0.34 ENSDART00000122815
ENSDART00000123443
ENSDART00000124094
daxx
death-domain associated protein
chr19_+_2631565 0.34 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr23_+_45845159 0.34 ENSDART00000023944
lmnl3
lamin L3
chr8_-_52938439 0.33 ENSDART00000168185
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr5_+_31779911 0.33 ENSDART00000098163
slc25a25b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25b
chr19_-_432083 0.33 ENSDART00000165371
dus3l
dihydrouridine synthase 3-like (S. cerevisiae)
chr21_-_19919918 0.33 ENSDART00000137307
ENSDART00000142523
ENSDART00000065670
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr13_-_7233811 0.32 ENSDART00000162026
ninl
ninein-like
chr11_-_34478225 0.32 ENSDART00000189604
xxylt1
xyloside xylosyltransferase 1
chr17_-_50045375 0.32 ENSDART00000184639
FO834825.2

chr12_+_10116912 0.32 ENSDART00000189630
si:dkeyp-118b1.2
si:dkeyp-118b1.2
chr9_+_54716436 0.32 ENSDART00000000552
ofd1
oral-facial-digital syndrome 1
chr3_-_29671653 0.32 ENSDART00000132083
sult3st1
sulfotransferase family 3, cytosolic sulfotransferase 1
chr10_-_2943474 0.32 ENSDART00000188698
oclna
occludin a
chr1_+_7414318 0.32 ENSDART00000127426
si:ch73-383l1.1
si:ch73-383l1.1
chr21_+_38855551 0.31 ENSDART00000171977
ddx52
DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
chr19_-_10207103 0.31 ENSDART00000151629
znf865
zinc finger protein 865
chr1_-_9195629 0.31 ENSDART00000143587
ENSDART00000192174
ern2
endoplasmic reticulum to nucleus signaling 2
chr9_-_55128839 0.31 ENSDART00000085135
tbl1x
transducin beta like 1 X-linked
chr20_-_13623882 0.31 ENSDART00000125218
ENSDART00000152499
sytl3
synaptotagmin-like 3
chr13_+_46941930 0.31 ENSDART00000056962
fbxo5
F-box protein 5
chr25_-_37319117 0.31 ENSDART00000044499
igl4v9
immunoglobulin light 4 variable 9
chr7_+_20393386 0.31 ENSDART00000173471
si:dkey-33c9.6
si:dkey-33c9.6
chr19_-_47997424 0.30 ENSDART00000081675
ctnnb2
catenin, beta 2
chr5_-_40178092 0.30 ENSDART00000146664
wdfy3
WD repeat and FYVE domain containing 3
chr15_-_1001177 0.30 ENSDART00000160730
zgc:162936
zgc:162936
chr15_+_5116179 0.30 ENSDART00000101937
pgm2l1
phosphoglucomutase 2-like 1
chr11_-_35171768 0.30 ENSDART00000192896
traip
TRAF-interacting protein
chr3_+_60607241 0.30 ENSDART00000167512
mfsd11
major facilitator superfamily domain containing 11
chr11_-_27962757 0.30 ENSDART00000147386
ece1
endothelin converting enzyme 1
chr10_-_45210184 0.30 ENSDART00000167128
pargl
poly (ADP-ribose) glycohydrolase, like
chr1_+_51391082 0.30 ENSDART00000063936
atg4da
autophagy related 4D, cysteine peptidase a
chr2_-_34138400 0.29 ENSDART00000056667
cenpl
centromere protein L
chr20_-_16078741 0.29 ENSDART00000021550
ralgps2
Ral GEF with PH domain and SH3 binding motif 2
chr12_+_32292564 0.29 ENSDART00000152945
ANKFN1
si:ch211-277e21.2
chr24_+_33802528 0.29 ENSDART00000136040
ENSDART00000147499
ENSDART00000182322
atg9b
autophagy related 9B
chr22_-_34979139 0.29 ENSDART00000116455
ENSDART00000133537
arhgap19
Rho GTPase activating protein 19
chr22_-_3299100 0.29 ENSDART00000160305
si:zfos-943e10.1
si:zfos-943e10.1
chr7_-_16596938 0.29 ENSDART00000134548
e2f8
E2F transcription factor 8
chr14_-_34512859 0.29 ENSDART00000140368
si:ch211-232m8.3
si:ch211-232m8.3
chr7_-_16597130 0.29 ENSDART00000144118
e2f8
E2F transcription factor 8
chr6_+_515181 0.28 ENSDART00000171374
CACNA1I (1 of many)
si:ch73-379f7.5
chr9_-_20853439 0.28 ENSDART00000028247
ENSDART00000133321
gdap2
ganglioside induced differentiation associated protein 2
chr17_-_5424175 0.28 ENSDART00000171063
ENSDART00000188102
supt3h
SPT3 homolog, SAGA and STAGA complex component
chr7_+_41812636 0.28 ENSDART00000174333
orc6
origin recognition complex, subunit 6
chr7_-_4461104 0.28 ENSDART00000023090
ENSDART00000140770
slc12a10.1
solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 1
chr14_-_16810401 0.28 ENSDART00000158396
ENSDART00000170758
tcirg1b
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr20_-_25902141 0.28 ENSDART00000142611
ENSDART00000024821
elmsan1a
ELM2 and Myb/SANT-like domain containing 1a
chr8_-_10961991 0.28 ENSDART00000139603
trim33
tripartite motif containing 33
chr19_-_42238440 0.28 ENSDART00000132591
si:ch211-191i18.4
si:ch211-191i18.4
chr10_+_41914084 0.27 ENSDART00000009227
orai1b
ORAI calcium release-activated calcium modulator 1b
chr7_-_12789251 0.27 ENSDART00000052750
adamtsl3
ADAMTS-like 3
chr25_+_3648497 0.27 ENSDART00000160017
CABZ01058261.1

chr5_-_2672492 0.27 ENSDART00000192337
CABZ01072548.1

chr19_-_42238003 0.27 ENSDART00000151022
si:ch211-191i18.4
si:ch211-191i18.4
chr8_-_37101581 0.27 ENSDART00000185922
zgc:162200
zgc:162200
chr14_-_48765262 0.27 ENSDART00000166463
cnot6b
CCR4-NOT transcription complex, subunit 6b
chr20_-_13624618 0.27 ENSDART00000063818
sytl3
synaptotagmin-like 3
chr6_+_13787855 0.27 ENSDART00000182899
tmem198b
transmembrane protein 198b
chr5_-_39171302 0.27 ENSDART00000020808
paqr3a
progestin and adipoQ receptor family member IIIa
chr23_-_2880191 0.27 ENSDART00000022413
zhx3
zinc fingers and homeoboxes 3
chr24_-_19719240 0.27 ENSDART00000135405
csrnp1b
cysteine-serine-rich nuclear protein 1b
chr15_+_22394074 0.26 ENSDART00000109931
oafa
OAF homolog a (Drosophila)
chr3_-_48612078 0.26 ENSDART00000169923
ndel1b
nudE neurodevelopment protein 1-like 1b
chr1_+_16621345 0.26 ENSDART00000149026
pcm1
pericentriolar material 1
chr12_+_22407852 0.26 ENSDART00000178840
hdlbpb
high density lipoprotein binding protein b
chr1_-_52447364 0.26 ENSDART00000140740
si:ch211-217k17.10
si:ch211-217k17.10
chr9_+_27329640 0.26 ENSDART00000111039
GTPBP8
si:rp71-84d19.3
chr19_-_41991104 0.26 ENSDART00000087055
trioa
trio Rho guanine nucleotide exchange factor a
chr16_+_13965923 0.26 ENSDART00000103857
zgc:162509
zgc:162509
chr22_-_15437242 0.26 ENSDART00000063719
rpp21
ribonuclease P 21 subunit
chr3_-_15679107 0.26 ENSDART00000080441
zgc:66443
zgc:66443
chr25_-_37322081 0.26 ENSDART00000128285
igl4v10
immunoglobulin light 4 variable 10
chr2_-_45510699 0.25 ENSDART00000024034
ENSDART00000145634
gpsm2
G protein signaling modulator 2
chr3_-_61362398 0.25 ENSDART00000156177
si:dkey-111k8.3
si:dkey-111k8.3
chr20_-_44576949 0.25 ENSDART00000148639
ubxn2a
UBX domain protein 2A
chr2_+_35880600 0.25 ENSDART00000004277
lamc1
laminin, gamma 1
chr13_-_24826607 0.25 ENSDART00000087786
ENSDART00000186951
slka
STE20-like kinase a
chr23_+_45845423 0.25 ENSDART00000183404
lmnl3
lamin L3
chr3_+_18846488 0.25 ENSDART00000148133
tmem104
transmembrane protein 104
chr18_-_7677208 0.25 ENSDART00000092456
shank3a
SH3 and multiple ankyrin repeat domains 3a
chr7_+_5975194 0.25 ENSDART00000123660
hist1h2a11
histone cluster 1 H2A family member 11
chr7_+_1579236 0.25 ENSDART00000172830
supt16h
SPT16 homolog, facilitates chromatin remodeling subunit
chr12_+_47794089 0.25 ENSDART00000160726
polr3a
polymerase (RNA) III (DNA directed) polypeptide A
chr24_+_21676921 0.25 ENSDART00000066677
si:ch211-140b10.6
si:ch211-140b10.6
chr8_+_8196087 0.25 ENSDART00000026965
plxnb3
plexin B3
chr21_-_41818359 0.24 ENSDART00000046076
CU929230.1

chr5_+_65087226 0.24 ENSDART00000183187
ptrh1
peptidyl-tRNA hydrolase 1 homolog
chr23_-_20002459 0.24 ENSDART00000163396
b4galt3
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr21_-_31013817 0.24 ENSDART00000065504
ncbp3
nuclear cap binding subunit 3
chr8_-_53960349 0.24 ENSDART00000160074
cdk11b
cyclin-dependent kinase 11B
chr17_+_22381215 0.24 ENSDART00000162670
ENSDART00000128875
slc8a1b
solute carrier family 8 (sodium/calcium exchanger), member 1b
chr17_-_5610514 0.24 ENSDART00000004043
enpp4
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr25_-_13789955 0.24 ENSDART00000167742
ENSDART00000165116
ENSDART00000171461
ckap5
cytoskeleton associated protein 5
chr23_+_42272588 0.24 ENSDART00000164907
CABZ01065131.1

chr18_+_13248956 0.24 ENSDART00000080709
plcg2
phospholipase C, gamma 2
chr16_-_13965518 0.24 ENSDART00000138304
si:dkey-85k15.4
si:dkey-85k15.4
chr7_-_5375214 0.24 ENSDART00000033316
vangl2
VANGL planar cell polarity protein 2
chr20_-_6131686 0.24 ENSDART00000145964
ENSDART00000086578
ENSDART00000164090
pum2
pumilio RNA-binding family member 2
chr4_+_5832311 0.24 ENSDART00000121743
ENSDART00000158233
ENSDART00000165187
si:ch73-352p4.5
si:ch73-352p4.5
chr25_+_17689565 0.24 ENSDART00000171965
galnt18a
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18a
chr25_+_27937585 0.24 ENSDART00000151994
cadps2
Ca++-dependent secretion activator 2
chr8_+_23726244 0.23 ENSDART00000132734
mkrn4
makorin, ring finger protein, 4
chr20_+_34501152 0.23 ENSDART00000143765
gorab
golgin, rab6-interacting
chr13_+_49727333 0.23 ENSDART00000168799
ENSDART00000037559
ggps1
geranylgeranyl diphosphate synthase 1
chr11_-_669270 0.23 ENSDART00000172834
pparg
peroxisome proliferator-activated receptor gamma
chr23_-_6722101 0.23 ENSDART00000157828
baz2a
bromodomain adjacent to zinc finger domain, 2A
chr15_+_784149 0.23 ENSDART00000155114
znf970
zinc finger protein 970
chr7_-_73854476 0.23 ENSDART00000186481
zgc:173552
zgc:173552
chr17_-_11357851 0.23 ENSDART00000153915
si:ch211-185a18.2
si:ch211-185a18.2
chr18_+_7611298 0.23 ENSDART00000062156
odf3b
outer dense fiber of sperm tails 3B
chr5_+_33488860 0.23 ENSDART00000135571
si:dkey-238j22.1
si:dkey-238j22.1
chr9_-_49964810 0.23 ENSDART00000167098
scn1a
sodium channel, voltage-gated, type I, alpha
chr21_+_6114709 0.23 ENSDART00000065858
fpgs
folylpolyglutamate synthase
chr2_-_45510223 0.23 ENSDART00000113058
gpsm2
G protein signaling modulator 2
chr19_+_42886413 0.23 ENSDART00000151298
arpp21
cAMP-regulated phosphoprotein, 21
chr17_+_26829985 0.23 ENSDART00000181269
jade1
jade family PHD finger 1
chr13_+_28785814 0.23 ENSDART00000039028
nsmce4a
NSE4 homolog A, SMC5-SMC6 complex component
chr6_+_19948043 0.23 ENSDART00000182636
pik3r5
phosphoinositide-3-kinase, regulatory subunit 5
chr1_+_49814942 0.23 ENSDART00000164936
lef1
lymphoid enhancer-binding factor 1
chr8_+_20503842 0.23 ENSDART00000100328
csnk1g2b
casein kinase 1, gamma 2b
chr13_+_42762226 0.23 ENSDART00000135231
cdh23
cadherin-related 23
chr7_+_29012033 0.22 ENSDART00000173909
ENSDART00000145762
dnaaf1
dynein, axonemal, assembly factor 1
chr6_+_54154807 0.22 ENSDART00000061735
nudt3b
nudix (nucleoside diphosphate linked moiety X)-type motif 3b
chr19_+_40069524 0.22 ENSDART00000151365
ENSDART00000140926
zmym4
zinc finger, MYM-type 4
chr23_-_478201 0.22 ENSDART00000140749
si:ch73-181d5.4
si:ch73-181d5.4
chr3_+_19687217 0.22 ENSDART00000141937
tlk2
tousled-like kinase 2
chr25_+_32390794 0.22 ENSDART00000012600
galk2
galactokinase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of cux2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
0.2 0.7 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.2 2.6 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.4 GO:0060571 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.1 0.5 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.6 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.6 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.1 0.9 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.1 0.3 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.1 0.5 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.3 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.1 0.3 GO:1903723 negative regulation of centriole elongation(GO:1903723)
0.1 1.3 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 0.2 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 0.5 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.5 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.1 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.3 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.3 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 0.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.3 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.1 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.3 GO:0000012 single strand break repair(GO:0000012)
0.1 0.3 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.1 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.2 GO:2000677 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.0 0.2 GO:0002568 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0 0.2 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.1 GO:0021611 facial nerve formation(GO:0021611)
0.0 0.2 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
0.0 0.4 GO:0021588 cerebellum formation(GO:0021588)
0.0 0.2 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.0 0.5 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.2 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.0 0.2 GO:1901906 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.5 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.3 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 1.3 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.4 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.3 GO:0048569 post-embryonic organ development(GO:0048569)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.4 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0097107 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.4 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.2 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.2 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.2 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.3 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.6 GO:0048885 neuromast deposition(GO:0048885)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.2 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 0.5 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.4 GO:0061055 myotome development(GO:0061055)
0.0 0.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0017006 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.6 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.2 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.2 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.2 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.7 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.3 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0098971 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.1 GO:0033363 secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.0 0.2 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 0.2 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.6 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.4 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:0014005 microglia development(GO:0014005)
0.0 0.2 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.2 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.7 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.3 GO:0060021 palate development(GO:0060021)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.5 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0060337 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.2 GO:0031579 membrane raft assembly(GO:0001765) membrane raft organization(GO:0031579) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.5 GO:0009648 photoperiodism(GO:0009648)
0.0 0.1 GO:0071871 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.0 0.5 GO:0000723 telomere maintenance(GO:0000723) telomere organization(GO:0032200)
0.0 0.1 GO:0098920 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.0 GO:0061400 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion(GO:0061400)
0.0 0.1 GO:0060760 positive regulation of cytokine-mediated signaling pathway(GO:0001961) positive regulation of response to cytokine stimulus(GO:0060760)
0.0 0.1 GO:0044211 CTP salvage(GO:0044211)
0.0 0.2 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 0.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.3 GO:0051928 positive regulation of calcium ion transport(GO:0051928)
0.0 0.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.7 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.1 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.2 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.3 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.1 GO:0031649 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.3 GO:0051923 sulfation(GO:0051923)
0.0 0.4 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:1902269 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.3 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.2 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.0 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.5 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.3 GO:0070209 ASTRA complex(GO:0070209)
0.1 0.8 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.3 GO:0097268 cytoophidium(GO:0097268)
0.1 0.3 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.3 GO:0032426 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.0 0.2 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.2 GO:0035101 FACT complex(GO:0035101)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.2 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.0 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.7 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0005675 holo TFIIH complex(GO:0005675) carboxy-terminal domain protein kinase complex(GO:0032806)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.2 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.4 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.1 GO:0032838 cell projection cytoplasm(GO:0032838)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 1.5 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.6 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.3 GO:0000407 pre-autophagosomal structure(GO:0000407)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 GO:0035804 structural constituent of egg coat(GO:0035804)
0.2 0.6 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.2 0.9 GO:0047192 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.7 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 0.4 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.7 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.5 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.3 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.1 0.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.2 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.2 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0008311 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.2 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.1 GO:0030623 U5 snRNA binding(GO:0030623)
0.0 0.3 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.2 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.0 0.4 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0098634 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.3 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.2 GO:0035197 siRNA binding(GO:0035197)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.7 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.0 0.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.1 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.1 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.2 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.0 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.0 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.8 GO:0046332 SMAD binding(GO:0046332)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.0 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.7 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.2 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 PID EPO PATHWAY EPO signaling pathway
0.0 0.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.8 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.2 PID AURORA A PATHWAY Aurora A signaling
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.6 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.8 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 0.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 1.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.1 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing