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PRJNA195909:zebrafish embryo and larva development

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Results for e2f1_e2f7

Z-value: 3.54

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Transcription factors associated with e2f1_e2f7

Gene Symbol Gene ID Gene Info
e2f1
ENSDARG00000103868 E2F transcription factor 1
e2f7
ENSDARG00000008986 E2F transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
e2f7dr11_v1_chr4_-_2545310_2545345-0.571.1e-01Click!
e2f1dr11_v1_chr23_-_43486714_43486714-0.068.8e-01Click!

Activity profile of e2f1_e2f7 motif

Sorted Z-values of e2f1_e2f7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_14277003 8.90 ENSDART00000006628
zgc:173742
zgc:173742
chr2_-_52550135 6.35 ENSDART00000044411
gna11b
guanine nucleotide binding protein (G protein), alpha 11b (Gq class)
chr7_+_24814866 5.95 ENSDART00000173581
si:ch211-226l4.6
si:ch211-226l4.6
chr22_-_38274188 5.47 ENSDART00000139420
ENSDART00000015117
elavl2
ELAV like neuron-specific RNA binding protein 2
chr10_+_6884123 5.31 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr23_-_29357764 5.26 ENSDART00000156512
si:ch211-129o18.4
si:ch211-129o18.4
chr13_+_31402067 4.82 ENSDART00000019202
tdrd9
tudor domain containing 9
chr21_+_34992550 4.73 ENSDART00000109041
ENSDART00000135400
tmprss15
transmembrane protease, serine 15
chr20_+_35438300 4.48 ENSDART00000102504
ENSDART00000153249
tdrd6
tudor domain containing 6
chr1_+_12196688 4.40 ENSDART00000143839
tdrd7a
tudor domain containing 7 a
chr19_-_48391415 4.35 ENSDART00000170726
ENSDART00000169577
si:ch73-359m17.2
si:ch73-359m17.2
chr16_+_53252951 4.31 ENSDART00000126543
si:ch211-269k10.5
si:ch211-269k10.5
chr23_+_44236855 4.06 ENSDART00000130147
ENSDART00000051907
MEPCE
si:ch1073-157b13.1
chr18_+_15271993 4.01 ENSDART00000099777
si:dkey-103i16.6
si:dkey-103i16.6
chr2_-_57900430 3.98 ENSDART00000132245
ENSDART00000140060
si:dkeyp-68b7.7
si:dkeyp-68b7.7
chr23_-_18057851 3.95 ENSDART00000173075
ENSDART00000173230
ENSDART00000173135
ENSDART00000173431
ENSDART00000173068
ENSDART00000172987
zgc:92287
zgc:92287
chr4_+_13586455 3.82 ENSDART00000187230
tnpo3
transportin 3
chr6_+_54496808 3.61 ENSDART00000156263
si:ch211-233f11.5
si:ch211-233f11.5
chr8_+_29636431 3.56 ENSDART00000133047
smarcad1a
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a
chr19_+_41006975 3.50 ENSDART00000138555
ENSDART00000049842
casd1
CAS1 domain containing 1
chr5_+_51248784 3.48 ENSDART00000159571
ENSDART00000189513
ENSDART00000092285
msh3
mutS homolog 3 (E. coli)
chr25_-_36370292 3.42 ENSDART00000152766
CR354435.1
Histone H2B 1/2
chr13_-_35908275 3.39 ENSDART00000013961
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr9_-_746317 3.38 ENSDART00000129632
ENSDART00000130720
usp37
ubiquitin specific peptidase 37
chr4_+_13586689 3.36 ENSDART00000067161
ENSDART00000138201
tnpo3
transportin 3
chr8_-_1219815 3.34 ENSDART00000016800
ENSDART00000149969
znf367
zinc finger protein 367
chr1_+_27690 3.30 ENSDART00000162928
eed
embryonic ectoderm development
chr8_+_29635968 3.29 ENSDART00000139029
ENSDART00000091409
smarcad1a
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a
chr25_+_32496877 3.25 ENSDART00000132698
ctdspl2a
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2a
chr18_-_7456378 3.20 ENSDART00000081459
pdp2
putative pyruvate dehydrogenase phosphatase isoenzyme 2
chr20_-_29498178 3.16 ENSDART00000152986
ENSDART00000027851
ENSDART00000152954
rrm2
ribonucleotide reductase M2 polypeptide
chr21_+_30721733 3.15 ENSDART00000040443
zgc:110224
zgc:110224
chr17_-_11368662 3.14 ENSDART00000159061
ENSDART00000188694
ENSDART00000190932
si:ch211-185a18.2
si:ch211-185a18.2
chr7_+_31374383 3.12 ENSDART00000085505
ctdspl2b
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2b
chr15_-_1485086 3.10 ENSDART00000191651
si:dkeyp-97b10.3
si:dkeyp-97b10.3
chr5_+_24047292 3.06 ENSDART00000029889
ctdnep1a
CTD nuclear envelope phosphatase 1a
chr23_-_6722101 3.06 ENSDART00000157828
baz2a
bromodomain adjacent to zinc finger domain, 2A
chr5_-_71765780 3.05 ENSDART00000011955
gpsm1b
G protein signaling modulator 1b
chr13_-_35907768 2.99 ENSDART00000147522
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr2_+_23081247 2.90 ENSDART00000099702
ENSDART00000088867
mfsd12a
major facilitator superfamily domain containing 12a
chr3_-_35865040 2.88 ENSDART00000102952
suz12a
SUZ12 polycomb repressive complex 2a subunit
chr10_+_6010570 2.84 ENSDART00000190025
ENSDART00000163680
hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr7_-_73854476 2.81 ENSDART00000186481
zgc:173552
zgc:173552
chr20_+_13141408 2.78 ENSDART00000034098
dtl
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr6_-_9282080 2.75 ENSDART00000159506
ccdc14
coiled-coil domain containing 14
chr20_-_33487729 2.74 ENSDART00000061843
smek1
SMEK homolog 1, suppressor of mek1 (Dictyostelium)
chr7_+_24881680 2.67 ENSDART00000058843
krcp
kelch repeat-containing protein
chr5_+_39099380 2.67 ENSDART00000166657
bmp2k
BMP2 inducible kinase
chr15_+_17406920 2.64 ENSDART00000081059
rps6kb1b
ribosomal protein S6 kinase b, polypeptide 1b
chr5_-_67241633 2.63 ENSDART00000114783
clip1a
CAP-GLY domain containing linker protein 1a
chr21_-_44731865 2.63 ENSDART00000013814
ammecr1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 homolog (human)
chr11_+_13176568 2.62 ENSDART00000125371
ENSDART00000123257
mknk1
MAP kinase interacting serine/threonine kinase 1
chr17_+_21514777 2.61 ENSDART00000154633
chst15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr13_-_86847 2.61 ENSDART00000158062
pole2
polymerase (DNA directed), epsilon 2
chr20_-_37933237 2.61 ENSDART00000142567
ENSDART00000036371
ENSDART00000061445
angel2
angel homolog 2 (Drosophila)
chr25_+_32390794 2.59 ENSDART00000012600
galk2
galactokinase 2
chr22_-_24992532 2.58 ENSDART00000102751
si:dkey-179j5.5
si:dkey-179j5.5
chr15_-_1484795 2.57 ENSDART00000129356
si:dkeyp-97b10.3
si:dkeyp-97b10.3
chr8_-_18211605 2.56 ENSDART00000114177
CT025742.1

chr2_+_41926707 2.54 ENSDART00000023208
zgc:110183
zgc:110183
chr20_+_35445462 2.54 ENSDART00000124497
tdrd6
tudor domain containing 6
chr1_+_58608978 2.51 ENSDART00000152744
si:ch73-236c18.9
si:ch73-236c18.9
chr20_+_33994580 2.50 ENSDART00000061729
si:dkey-97o5.1
si:dkey-97o5.1
chr20_-_28698172 2.50 ENSDART00000190635
sipa1l1
signal-induced proliferation-associated 1 like 1
chr5_-_68779747 2.35 ENSDART00000192636
ENSDART00000188039
mepce
methylphosphate capping enzyme
chr7_+_71586485 2.32 ENSDART00000165582
smchd1
structural maintenance of chromosomes flexible hinge domain containing 1
chr10_-_7472323 2.32 ENSDART00000163702
ENSDART00000167054
ENSDART00000167706
nrg1
neuregulin 1
chr7_-_6429031 2.31 ENSDART00000173413
zgc:112234
zgc:112234
chr2_+_23081402 2.30 ENSDART00000183073
mfsd12a
major facilitator superfamily domain containing 12a
chr19_-_2582858 2.29 ENSDART00000113829
cdca7b
cell division cycle associated 7b
chr23_-_18057553 2.27 ENSDART00000173102
ENSDART00000058742
zgc:92287
zgc:92287
chr25_+_32496723 2.26 ENSDART00000087978
ctdspl2a
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2a
chr19_-_34873566 2.24 ENSDART00000016057
ctnnal1
catenin (cadherin-associated protein), alpha-like 1
chr19_-_11846958 2.21 ENSDART00000148516
ctdp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr13_+_48358467 2.20 ENSDART00000171080
ENSDART00000162531
msh6
mutS homolog 6 (E. coli)
chr21_-_23017478 2.20 ENSDART00000024309
rb1
retinoblastoma 1
chr2_-_45663945 2.19 ENSDART00000075080
prpf38b
pre-mRNA processing factor 38B
chr7_-_6445129 2.18 ENSDART00000172825
FP325123.2
Histone H3.2
chr12_+_17603528 2.16 ENSDART00000111565
pms2
PMS1 homolog 2, mismatch repair system component
chr24_+_9693951 2.15 ENSDART00000082411
topbp1
DNA topoisomerase II binding protein 1
chr24_-_13349802 2.13 ENSDART00000164729
terf1
telomeric repeat binding factor (NIMA-interacting) 1
chr25_-_35112466 2.12 ENSDART00000183481
CU302436.4

chr14_+_14841685 2.10 ENSDART00000158291
ENSDART00000162039
slbp
stem-loop binding protein
chr15_-_30832897 2.08 ENSDART00000152330
msi2b
musashi RNA-binding protein 2b
chr22_-_20419660 2.05 ENSDART00000105520
pias4a
protein inhibitor of activated STAT, 4a
chr3_-_61377127 2.03 ENSDART00000155932
si:dkey-111k8.2
si:dkey-111k8.2
chr13_-_25548733 2.03 ENSDART00000168099
ENSDART00000135788
ENSDART00000077655
mcmbp
minichromosome maintenance complex binding protein
chr18_+_20226843 2.00 ENSDART00000100632
tle3a
transducin-like enhancer of split 3a
chr6_+_33931740 2.00 ENSDART00000130492
ENSDART00000151213
orc1
origin recognition complex, subunit 1
chr22_-_22301672 1.95 ENSDART00000111711
chaf1a
chromatin assembly factor 1, subunit A (p150)
chr7_-_50633285 1.94 ENSDART00000174018
crtc3
CREB regulated transcription coactivator 3
chr23_+_39413163 1.93 ENSDART00000184254
src
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr7_+_41812636 1.93 ENSDART00000174333
orc6
origin recognition complex, subunit 6
chr7_+_55518519 1.93 ENSDART00000098476
ENSDART00000149915
cdt1
chromatin licensing and DNA replication factor 1
chr2_-_53500424 1.92 ENSDART00000037557
admp
anti-dorsalizing morphogenic protein
chr12_+_47446158 1.92 ENSDART00000152857
fmn2b
formin 2b
chr15_-_30832171 1.89 ENSDART00000152414
ENSDART00000152790
msi2b
musashi RNA-binding protein 2b
chr3_-_18737126 1.89 ENSDART00000055767
e4f1
E4F transcription factor 1
chr18_+_22287084 1.86 ENSDART00000151919
ENSDART00000181644
ctcf
CCCTC-binding factor (zinc finger protein)
chr6_-_33916756 1.86 ENSDART00000137447
ENSDART00000138488
nasp
nuclear autoantigenic sperm protein (histone-binding)
chr24_+_26329018 1.85 ENSDART00000145752
mynn
myoneurin
chr9_-_10068004 1.85 ENSDART00000011922
ENSDART00000162818
spopla
speckle-type POZ protein-like a
chr7_-_16582187 1.85 ENSDART00000131726
e2f8
E2F transcription factor 8
chr7_+_41812817 1.83 ENSDART00000174165
orc6
origin recognition complex, subunit 6
chr1_+_57311901 1.81 ENSDART00000149397
mycbpap
mycbp associated protein
chr25_-_35124576 1.81 ENSDART00000128017
zgc:171759
zgc:171759
chr1_-_44000940 1.80 ENSDART00000134932
ENSDART00000138447
zgc:66472
zgc:66472
chr1_+_49415281 1.78 ENSDART00000015007
taf5
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr8_+_37749263 1.77 ENSDART00000108556
ENSDART00000147942
npm2a
nucleophosmin/nucleoplasmin, 2a
chr24_+_26328787 1.76 ENSDART00000003884
mynn
myoneurin
chr24_-_13349464 1.76 ENSDART00000134482
ENSDART00000139212
terf1
telomeric repeat binding factor (NIMA-interacting) 1
chr21_-_11655010 1.76 ENSDART00000144370
ENSDART00000139814
ENSDART00000139289
cast
calpastatin
chr5_+_41477526 1.75 ENSDART00000153567
pias2
protein inhibitor of activated STAT, 2
chr3_+_43086548 1.75 ENSDART00000163579
si:dkey-43p13.5
si:dkey-43p13.5
chr14_-_16775158 1.75 ENSDART00000113711
ENSDART00000144781
ENSDART00000160411
mrnip
MRN complex interacting protein
chr23_+_20518504 1.75 ENSDART00000114246
adnpb
activity-dependent neuroprotector homeobox b
chr10_+_16911951 1.71 ENSDART00000164933
UNC13B (1 of many)
unc-13 homolog B
chr5_+_34549845 1.69 ENSDART00000139317
aif1l
allograft inflammatory factor 1-like
chr8_-_22660678 1.69 ENSDART00000181258
iqsec2a
IQ motif and Sec7 domain 2a
chr4_-_2380173 1.69 ENSDART00000177727
nap1l1
nucleosome assembly protein 1-like 1
chr1_+_14020445 1.68 ENSDART00000079716
hpf1
histone PARylation factor 1
chr14_+_26247319 1.68 ENSDART00000192793
CCDC69
coiled-coil domain containing 69
chr5_+_20453874 1.66 ENSDART00000124545
ENSDART00000008402
sart3
squamous cell carcinoma antigen recognized by T cells 3
chr19_-_47570672 1.66 ENSDART00000112155
rrm2
ribonucleotide reductase M2 polypeptide
chr8_-_20230559 1.65 ENSDART00000193677
mllt1a
MLLT1, super elongation complex subunit a
chr1_+_58613972 1.65 ENSDART00000162460
si:ch73-221f6.3
si:ch73-221f6.3
chr3_-_7897305 1.63 ENSDART00000169757
ubn2b
ubinuclein 2b
chr21_+_34119759 1.61 ENSDART00000024750
ENSDART00000128242
hmgb3b
high mobility group box 3b
chr25_-_35047838 1.61 ENSDART00000155060
CU302436.3

chr19_+_20495249 1.61 ENSDART00000090810
kcnh8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr25_+_35067318 1.60 ENSDART00000186828
CU302436.1

chr7_+_41812190 1.59 ENSDART00000113732
ENSDART00000174137
orc6
origin recognition complex, subunit 6
chr13_+_28785814 1.57 ENSDART00000039028
nsmce4a
NSE4 homolog A, SMC5-SMC6 complex component
chr1_+_58620953 1.56 ENSDART00000167632
si:ch73-221f6.4
si:ch73-221f6.4
chr3_+_13603272 1.55 ENSDART00000185084
hspbp1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr7_-_29723761 1.54 ENSDART00000173560
vps13c
vacuolar protein sorting 13 homolog C (S. cerevisiae)
chr18_-_8380090 1.53 ENSDART00000141581
ENSDART00000081143
sephs1
selenophosphate synthetase 1
chr13_-_14929236 1.52 ENSDART00000020576
cdc25b
cell division cycle 25B
chr3_-_31086770 1.51 ENSDART00000103421
zgc:153292
zgc:153292
chr1_+_24557414 1.50 ENSDART00000076519
dctpp1
dCTP pyrophosphatase 1
chr8_+_8643901 1.49 ENSDART00000142076
ENSDART00000075624
usp11
ubiquitin specific peptidase 11
chr8_-_1698155 1.48 ENSDART00000186159
CABZ01065417.1

chr17_-_42799104 1.47 ENSDART00000154755
prkd3
protein kinase D3
chr12_-_2522487 1.46 ENSDART00000022471
ENSDART00000145213
mapk8b
mitogen-activated protein kinase 8b
chr22_+_24157807 1.46 ENSDART00000159165
b3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr1_-_59216197 1.46 ENSDART00000062426
lpar2b
lysophosphatidic acid receptor 2b
chr16_+_55078477 1.44 ENSDART00000170074
azi2
5-azacytidine induced 2
chr18_+_39327010 1.44 ENSDART00000012164
tmod2
tropomodulin 2
chr1_+_11992 1.44 ENSDART00000161842
cep97
centrosomal protein 97
chr25_+_36333993 1.43 ENSDART00000184379
CR354435.2

chr8_-_49725430 1.42 ENSDART00000135675
gkap1
G kinase anchoring protein 1
chr2_+_48073972 1.41 ENSDART00000186442
klf6b
Kruppel-like factor 6b
chr7_+_29080684 1.40 ENSDART00000173709
ENSDART00000173576
acd
ACD, shelterin complex subunit and telomerase recruitment factor
chr21_-_26483237 1.40 ENSDART00000169072
ENSDART00000147947
ankhd1
ankyrin repeat and KH domain containing 1
chr5_+_34549365 1.40 ENSDART00000009500
aif1l
allograft inflammatory factor 1-like
chr3_+_14571813 1.39 ENSDART00000146728
ENSDART00000171731
znf653
zinc finger protein 653
chr3_-_7897563 1.38 ENSDART00000185232
ubn2b
ubinuclein 2b
chr16_+_25608778 1.36 ENSDART00000077484
zhx2a
zinc fingers and homeoboxes 2a
chr8_+_622640 1.34 ENSDART00000051774
spinb
spindlin b
chr8_+_36509885 1.33 ENSDART00000109530
slc7a4
solute carrier family 7, member 4
chr22_+_2510828 1.32 ENSDART00000115348
ENSDART00000145611
zgc:173726
zgc:173726
chr2_-_122154 1.31 ENSDART00000156248
ENSDART00000004071
znfl2a
zinc finger-like gene 2a
chr13_-_11378355 1.29 ENSDART00000164566
akt3a
v-akt murine thymoma viral oncogene homolog 3a
chr22_+_2511045 1.28 ENSDART00000106425
zgc:173726
zgc:173726
chr9_-_2892250 1.27 ENSDART00000140695
cdca7a
cell division cycle associated 7a
chr18_+_7456888 1.27 ENSDART00000081468
terb1
telomere repeat binding bouquet formation protein 1
chr22_+_3045495 1.26 ENSDART00000164061
LO017843.1

chr6_+_48720617 1.26 ENSDART00000164142
ENSDART00000167131
si:dkeyp-6a3.1
si:dkeyp-6a3.1
chr4_+_5318901 1.25 ENSDART00000067378
si:ch211-214j24.10
si:ch211-214j24.10
chr2_-_37098785 1.24 ENSDART00000003670
zgc:101744
zgc:101744
chr24_+_41690545 1.23 ENSDART00000160069
lama1
laminin, alpha 1
chr20_+_44582318 1.21 ENSDART00000149000
ENSDART00000149775
ENSDART00000085416
atad2b
ATPase family, AAA domain containing 2B
chr25_-_35102781 1.20 ENSDART00000180881
ENSDART00000153747
si:dkey-108k21.24
si:dkey-108k21.24
chr3_-_25646149 1.19 ENSDART00000122735
usp43b
ubiquitin specific peptidase 43b
chr17_+_23730089 1.19 ENSDART00000034913
zgc:91976
zgc:91976
chr16_+_37891735 1.19 ENSDART00000178753
ENSDART00000142104
cep162
centrosomal protein 162
chr7_+_5960491 1.17 ENSDART00000145370
zgc:112234
zgc:112234
chr9_+_2020667 1.17 ENSDART00000157818
lnpa
limb and neural patterns a
chr1_+_11822 1.17 ENSDART00000166393
cep97
centrosomal protein 97
chr9_-_54361357 1.16 ENSDART00000149813
rad50
RAD50 homolog, double strand break repair protein
chr13_+_8255106 1.15 ENSDART00000080465
hells
helicase, lymphoid specific
chr14_-_22015232 1.14 ENSDART00000137795
ssrp1a
structure specific recognition protein 1a
chr11_+_1551603 1.14 ENSDART00000185383
ENSDART00000121489
ENSDART00000040577
mybl2b
v-myb avian myeloblastosis viral oncogene homolog-like 2b
chr10_+_44057502 1.13 ENSDART00000183868
grk3
G protein-coupled receptor kinase 3
chr17_-_868004 1.13 ENSDART00000112803
wdr20a
WD repeat domain 20a
chr21_+_1647990 1.13 ENSDART00000148540
fech
ferrochelatase
chr3_-_60589292 1.12 ENSDART00000157822
jmjd6
jumonji domain containing 6
chr19_+_25465025 1.12 ENSDART00000018553
rpa3
replication protein A3
chr6_+_12503849 1.12 ENSDART00000149529
stk24b
serine/threonine kinase 24b (STE20 homolog, yeast)
chr15_+_19884242 1.11 ENSDART00000154437
ENSDART00000054416
dyrk1ab
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b
chr10_+_44057177 1.11 ENSDART00000164610
grk3
G protein-coupled receptor kinase 3
chr16_+_40340523 1.11 ENSDART00000102571
mettl6
methyltransferase like 6
chr5_-_7712160 1.11 ENSDART00000168820
bmpr1ba
bone morphogenetic protein receptor, type IBa
chr5_-_23596339 1.10 ENSDART00000024815
fam76b
family with sequence similarity 76, member B
chr20_-_36559956 1.10 ENSDART00000026539
enah
enabled homolog (Drosophila)
chr8_+_18545185 1.09 ENSDART00000191398
tab3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr6_-_30689126 1.08 ENSDART00000065211
pars2
prolyl-tRNA synthetase 2, mitochondrial
chr13_+_26703922 1.08 ENSDART00000020946
fancl
Fanconi anemia, complementation group L
chr7_-_878473 1.07 ENSDART00000173567
si:cabz01080528.1
si:cabz01080528.1
chr10_-_15644904 1.07 ENSDART00000138389
ENSDART00000101191
ENSDART00000186559
ENSDART00000122170
smc5
structural maintenance of chromosomes 5

Network of associatons between targets according to the STRING database.

First level regulatory network of e2f1_e2f7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 7.0 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
1.0 5.2 GO:0043476 pigment accumulation(GO:0043476)
1.0 11.4 GO:0030719 P granule organization(GO:0030719)
1.0 4.8 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.9 2.8 GO:1902767 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.9 5.3 GO:0007603 phototransduction, visible light(GO:0007603)
0.8 3.2 GO:1904184 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.8 2.3 GO:1904871 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.8 2.3 GO:0060959 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.7 2.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.7 2.8 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.7 6.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.6 1.9 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.6 1.9 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
0.6 3.2 GO:0000012 single strand break repair(GO:0000012)
0.6 1.8 GO:0034398 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.6 3.1 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.6 6.8 GO:0000729 DNA double-strand break processing(GO:0000729)
0.6 1.7 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.6 2.8 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.5 4.8 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.5 8.9 GO:0006265 DNA topological change(GO:0006265)
0.5 1.5 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.5 1.4 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.5 1.8 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.4 2.6 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.4 1.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.4 1.5 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.4 3.4 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.4 2.6 GO:0006012 galactose metabolic process(GO:0006012)
0.4 1.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.4 2.5 GO:0009217 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.3 1.0 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.3 2.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.3 5.1 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.3 1.7 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.3 2.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.3 1.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.3 2.6 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.3 2.2 GO:0044030 regulation of DNA methylation(GO:0044030)
0.3 2.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.3 0.9 GO:0046104 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.3 2.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.3 1.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.3 1.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.3 2.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.3 1.9 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.3 1.9 GO:0000076 DNA replication checkpoint(GO:0000076)
0.3 1.5 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.3 1.5 GO:0001887 selenium compound metabolic process(GO:0001887)
0.3 1.8 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.2 4.0 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.2 1.5 GO:0089700 protein kinase D signaling(GO:0089700)
0.2 1.0 GO:0071947 protein K29-linked deubiquitination(GO:0035523) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) protein K33-linked deubiquitination(GO:1990168)
0.2 0.9 GO:0031053 primary miRNA processing(GO:0031053)
0.2 2.2 GO:0003315 heart rudiment formation(GO:0003315)
0.2 5.5 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.2 0.9 GO:0071733 establishment of mitotic sister chromatid cohesion(GO:0034087) establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2 1.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.2 2.0 GO:0061056 sclerotome development(GO:0061056)
0.2 1.5 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.2 0.6 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.2 6.6 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.2 1.1 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.2 0.9 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.2 0.9 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 10.7 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.2 1.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 2.7 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.2 3.1 GO:0097178 ruffle assembly(GO:0097178)
0.1 3.0 GO:0006298 mismatch repair(GO:0006298)
0.1 1.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.3 GO:0071514 genetic imprinting(GO:0071514)
0.1 0.5 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.5 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 1.1 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 2.9 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.7 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 1.9 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.1 1.5 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.3 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.1 0.4 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.7 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.1 3.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.1 2.2 GO:0021554 optic nerve development(GO:0021554)
0.1 0.9 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.9 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.1 2.6 GO:0019319 hexose biosynthetic process(GO:0019319)
0.1 2.6 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 1.7 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.1 0.9 GO:0046850 regulation of bone remodeling(GO:0046850)
0.1 0.9 GO:0003160 endocardium morphogenesis(GO:0003160)
0.1 2.3 GO:0016925 protein sumoylation(GO:0016925)
0.1 3.9 GO:0007062 sister chromatid cohesion(GO:0007062)
0.1 0.4 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 6.9 GO:0006334 nucleosome assembly(GO:0006334)
0.1 0.7 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 0.7 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.3 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 3.3 GO:0006342 chromatin silencing(GO:0006342)
0.1 0.1 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.1 1.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 2.8 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.9 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 1.3 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 1.1 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 5.3 GO:1903706 regulation of hemopoiesis(GO:1903706)
0.0 2.9 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 1.0 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.8 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0 1.2 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.6 GO:0016926 protein desumoylation(GO:0016926)
0.0 1.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 7.9 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.8 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.4 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.0 0.9 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.9 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.7 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.5 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.7 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 1.3 GO:1902275 regulation of chromatin organization(GO:1902275)
0.0 1.4 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 1.8 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.8 GO:0032355 response to estradiol(GO:0032355)
0.0 3.3 GO:0016579 protein deubiquitination(GO:0016579)
0.0 1.9 GO:0045010 actin nucleation(GO:0045010)
0.0 1.0 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.5 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.5 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 1.5 GO:0048916 posterior lateral line development(GO:0048916)
0.0 0.1 GO:0042148 strand invasion(GO:0042148)
0.0 0.1 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.6 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.7 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.7 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.4 GO:0051016 barbed-end actin filament capping(GO:0051016)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0033391 chromatoid body(GO:0033391)
1.2 3.5 GO:0032301 MutSalpha complex(GO:0032301)
0.9 2.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.8 5.7 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.8 5.6 GO:0032300 mismatch repair complex(GO:0032300)
0.8 3.2 GO:0033186 CAF-1 complex(GO:0033186)
0.7 2.9 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.6 3.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.6 3.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.6 7.0 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.5 14.5 GO:0043186 P granule(GO:0043186)
0.5 2.9 GO:0030870 Mre11 complex(GO:0030870)
0.4 1.2 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.4 2.6 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.3 4.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 1.0 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.3 7.1 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.3 7.1 GO:0035861 site of double-strand break(GO:0035861)
0.2 1.2 GO:0005879 axonemal microtubule(GO:0005879)
0.2 0.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 1.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 0.9 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.2 1.8 GO:0000792 heterochromatin(GO:0000792)
0.2 1.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.2 0.9 GO:0018444 translation release factor complex(GO:0018444)
0.2 5.2 GO:0005844 polysome(GO:0005844)
0.2 0.5 GO:1990077 primosome complex(GO:1990077)
0.2 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 1.7 GO:0035101 FACT complex(GO:0035101)
0.1 6.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.3 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.5 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 1.7 GO:0015030 Cajal body(GO:0015030)
0.1 0.5 GO:0016589 NURF complex(GO:0016589)
0.1 1.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 2.0 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 5.9 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 8.2 GO:0000786 nucleosome(GO:0000786)
0.1 1.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 3.1 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 1.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.8 GO:0043596 nuclear replication fork(GO:0043596)
0.1 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 1.0 GO:0032039 integrator complex(GO:0032039)
0.0 0.7 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 10.4 GO:0005730 nucleolus(GO:0005730)
0.0 3.1 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.4 GO:0097346 INO80-type complex(GO:0097346)
0.0 0.9 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 2.1 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 2.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.7 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 13.6 GO:0005654 nucleoplasm(GO:0005654)
0.0 0.7 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.9 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 4.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.2 GO:0005604 basement membrane(GO:0005604)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 7.0 GO:0032135 DNA insertion or deletion binding(GO:0032135)
1.3 3.9 GO:0071532 ankyrin repeat binding(GO:0071532)
0.9 2.8 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.9 2.8 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.8 3.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.8 6.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.8 3.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.7 4.8 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.7 8.9 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.5 1.5 GO:0004061 arylformamidase activity(GO:0004061)
0.4 2.5 GO:0008832 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793)
0.4 1.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.4 2.2 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.3 1.0 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.3 1.7 GO:0008432 JUN kinase binding(GO:0008432)
0.3 3.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.3 0.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.3 1.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 3.5 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.3 4.0 GO:0070403 NAD+ binding(GO:0070403)
0.3 1.8 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 1.5 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 2.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 2.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 0.6 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.2 1.7 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 1.8 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 2.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 0.6 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.2 1.4 GO:0035173 histone kinase activity(GO:0035173)
0.2 1.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.2 1.5 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.2 4.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 1.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.5 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 1.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 1.9 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 10.5 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.9 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.5 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.1 4.3 GO:0003684 damaged DNA binding(GO:0003684)
0.1 2.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 1.4 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 0.8 GO:0045735 nutrient reservoir activity(GO:0045735)
0.1 2.3 GO:0017069 snRNA binding(GO:0017069)
0.1 4.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 1.1 GO:0005522 profilin binding(GO:0005522)
0.1 0.7 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 1.5 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 1.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.9 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 1.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 8.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.5 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 1.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.7 GO:0005042 netrin receptor activity(GO:0005042)
0.1 6.2 GO:0042054 histone methyltransferase activity(GO:0042054)
0.1 1.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 2.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 1.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 1.4 GO:0005523 tropomyosin binding(GO:0005523)
0.1 5.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 0.2 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.6 GO:0030332 cyclin binding(GO:0030332)
0.1 2.6 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 6.6 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 0.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 2.7 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.7 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.9 GO:0030515 snoRNA binding(GO:0030515)
0.0 3.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 9.0 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 9.0 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.5 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 1.1 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 2.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.0 0.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 3.2 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 7.2 GO:0042393 histone binding(GO:0042393)
0.0 0.7 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.8 GO:0019213 deacetylase activity(GO:0019213)
0.0 6.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 4.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.3 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 1.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 2.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.9 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 4.2 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 3.1 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 1.8 GO:0015293 symporter activity(GO:0015293)
0.0 1.9 GO:0005125 cytokine activity(GO:0005125)
0.0 4.0 GO:0030695 GTPase regulator activity(GO:0030695)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 5.4 PID BARD1 PATHWAY BARD1 signaling events
0.1 1.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 0.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 5.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 2.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 2.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 1.9 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.0 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.6 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.0 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.3 9.4 REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION Genes involved in E2F mediated regulation of DNA replication
0.3 4.6 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.3 2.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3 3.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.3 4.5 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.2 2.8 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.2 3.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 1.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 2.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 2.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.2 0.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.9 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 3.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.1 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 2.2 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1 1.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 0.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.6 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 1.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.5 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 1.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.0 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling