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PRJNA195909:zebrafish embryo and larva development

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Results for e4f1+si:dkeyp-79b7.12

Z-value: 1.00

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Transcription factors associated with e4f1+si:dkeyp-79b7.12

Gene Symbol Gene ID Gene Info
e4f1
ENSDARG00000038243 E4F transcription factor 1
si_dkeyp-79b7.12
ENSDARG00000105305 si_dkeyp-79b7.12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
e4f1dr11_v1_chr3_-_18737126_187371260.781.3e-02Click!
si:dkeyp-79b7.12dr11_v1_chr22_+_2207502_22075020.599.6e-02Click!

Activity profile of e4f1+si:dkeyp-79b7.12 motif

Sorted Z-values of e4f1+si:dkeyp-79b7.12 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_44801968 2.27 ENSDART00000161846
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr17_+_25187226 1.58 ENSDART00000148431
cln8
CLN8, transmembrane ER and ERGIC protein
chr20_-_44576949 1.43 ENSDART00000148639
ubxn2a
UBX domain protein 2A
chr15_+_5116179 1.29 ENSDART00000101937
pgm2l1
phosphoglucomutase 2-like 1
chr19_+_42660158 1.28 ENSDART00000018328
fbxl2
F-box and leucine-rich repeat protein 2
chr23_-_32157865 1.24 ENSDART00000000876
nr4a1
nuclear receptor subfamily 4, group A, member 1
chr8_-_410199 1.21 ENSDART00000091177
ENSDART00000122979
ENSDART00000151331
ENSDART00000151155
trim36
tripartite motif containing 36
chr8_-_410728 1.14 ENSDART00000151255
trim36
tripartite motif containing 36
chr5_-_29531948 1.12 ENSDART00000098360
arrdc1a
arrestin domain containing 1a
chr5_+_44846434 1.10 ENSDART00000145299
ENSDART00000136521
kank1a
KN motif and ankyrin repeat domains 1a
chr9_+_33334501 1.03 ENSDART00000006867
ddx3a
DEAD (Asp-Glu-Ala-Asp) box helicase 3a
chr23_-_27506161 0.98 ENSDART00000145007
asb8
ankyrin repeat and SOCS box containing 8
chr19_-_3821678 0.91 ENSDART00000169639
si:dkey-206d17.12
si:dkey-206d17.12
chr17_+_1544903 0.91 ENSDART00000156244
ENSDART00000112183
cep170b
centrosomal protein 170B
chr14_+_30413758 0.85 ENSDART00000092953
cnot7
CCR4-NOT transcription complex, subunit 7
chr13_-_17464362 0.85 ENSDART00000145499
lrmda
leucine rich melanocyte differentiation associated
chr23_-_27505825 0.84 ENSDART00000137229
ENSDART00000013797
asb8
ankyrin repeat and SOCS box containing 8
chr2_-_19354622 0.83 ENSDART00000168627
zfyve9a
zinc finger, FYVE domain containing 9a
chr5_+_44846280 0.82 ENSDART00000084370
kank1a
KN motif and ankyrin repeat domains 1a
chr10_+_35554219 0.81 ENSDART00000077373
zdhhc20a
zinc finger, DHHC-type containing 20a
chr8_+_48965767 0.81 ENSDART00000008058
aak1a
AP2 associated kinase 1a
chr20_-_36671660 0.78 ENSDART00000134819
slc5a6a
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6a
chr16_-_41535690 0.76 ENSDART00000102662
rpp25l
ribonuclease P/MRP 25 subunit-like
chr24_-_41657005 0.76 ENSDART00000159109
CABZ01044099.1

chr13_-_8304605 0.75 ENSDART00000080460
atl2
atlastin GTPase 2
chr14_+_30413312 0.75 ENSDART00000186864
cnot7
CCR4-NOT transcription complex, subunit 7
chr15_+_46386261 0.75 ENSDART00000191793
igsf11
immunoglobulin superfamily member 11
chr15_-_27522387 0.73 ENSDART00000112643
brip1
BRCA1 interacting protein C-terminal helicase 1
chr16_-_13613475 0.72 ENSDART00000139102
dbpb
D site albumin promoter binding protein b
chr4_+_9011825 0.71 ENSDART00000058007
samm50l
sorting and assembly machinery component 50 homolog, like
chr16_+_26732086 0.71 ENSDART00000138496
rad54b
RAD54 homolog B (S. cerevisiae)
chr10_+_44940693 0.70 ENSDART00000157515
cnnm4a
cyclin and CBS domain divalent metal cation transport mediator 4a
chr14_-_38946808 0.69 ENSDART00000139293
gla
galactosidase, alpha
chr3_+_36713477 0.68 ENSDART00000181105
ENSDART00000161897
ENSDART00000189952
abcc1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
chr17_+_23554932 0.68 ENSDART00000135814
pank1a
pantothenate kinase 1a
chr4_-_26035770 0.67 ENSDART00000124514
usp44
ubiquitin specific peptidase 44
chr8_-_29822527 0.66 ENSDART00000167487
slc20a2
solute carrier family 20 (phosphate transporter), member 2
chr9_-_6501924 0.66 ENSDART00000168143
nck2a
NCK adaptor protein 2a
chr11_-_17782930 0.65 ENSDART00000080770
tmf1
TATA element modulatory factor 1
chr2_-_4032732 0.65 ENSDART00000158335
rab18b
RAB18B, member RAS oncogene family
chr17_-_2690083 0.64 ENSDART00000135374
ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr9_-_13963078 0.64 ENSDART00000193398
ENSDART00000061156
raph1a
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr12_-_34852342 0.63 ENSDART00000152968
si:dkey-21c1.1
si:dkey-21c1.1
chr4_+_9011448 0.63 ENSDART00000192357
samm50l
sorting and assembly machinery component 50 homolog, like
chr15_-_27522806 0.62 ENSDART00000149374
ENSDART00000187341
ENSDART00000183043
ENSDART00000189541
ENSDART00000190362
ENSDART00000193745
ENSDART00000187390
brip1
BRCA1 interacting protein C-terminal helicase 1
chr22_+_33362552 0.61 ENSDART00000101580
nicn1
nicolin 1
chr22_-_547748 0.60 ENSDART00000037455
ENSDART00000140101
ccnd3
cyclin D3
chr20_+_16639848 0.60 ENSDART00000063944
ENSDART00000152359
tmem30ab
transmembrane protein 30Ab
chr4_+_73051901 0.60 ENSDART00000174219
zgc:152938
zgc:152938
chr8_-_19266325 0.58 ENSDART00000036148
ENSDART00000137994
zgc:77486
zgc:77486
chr10_+_15603082 0.58 ENSDART00000024450
zfand5b
zinc finger, AN1-type domain 5b
chr8_+_44714336 0.58 ENSDART00000145801
elmod3
ELMO/CED-12 domain containing 3
chr5_-_25576462 0.58 ENSDART00000165147
si:dkey-229d2.4
si:dkey-229d2.4
chr25_-_23052707 0.58 ENSDART00000024633
dusp8a
dual specificity phosphatase 8a
chr11_+_42765963 0.56 ENSDART00000156080
ENSDART00000179888
tdrd3
tudor domain containing 3
chr3_+_61221194 0.54 ENSDART00000110030
lmtk2
lemur tyrosine kinase 2
chr3_-_11624694 0.52 ENSDART00000127157
hlfa
hepatic leukemia factor a
chr10_+_23099890 0.51 ENSDART00000135890
LTN1
si:dkey-175g6.5
chr7_+_1534820 0.51 ENSDART00000192997
tox4b
TOX high mobility group box family member 4 b
chr5_+_26921033 0.51 ENSDART00000051483
tm2d2
TM2 domain containing 2
chr17_+_8754426 0.50 ENSDART00000185519
edrf1
erythroid differentiation regulatory factor 1
chr6_+_112579 0.50 ENSDART00000034505
ap1m2
adaptor-related protein complex 1, mu 2 subunit
chr21_-_43474012 0.50 ENSDART00000065104
tmem185
transmembrane protein 185
chr15_-_41689981 0.50 ENSDART00000059327
spsb4b
splA/ryanodine receptor domain and SOCS box containing 4b
chr21_-_9782502 0.49 ENSDART00000158836
arhgap24
Rho GTPase activating protein 24
chr24_-_37326236 0.49 ENSDART00000003789
pdpk1b
3-phosphoinositide dependent protein kinase 1b
chr2_+_6999369 0.49 ENSDART00000050597
xpr1b
xenotropic and polytropic retrovirus receptor 1b
chr17_+_8754020 0.49 ENSDART00000105322
edrf1
erythroid differentiation regulatory factor 1
chr12_+_33320884 0.49 ENSDART00000188988
csnk1db
casein kinase 1, delta b
chr13_+_35856463 0.49 ENSDART00000171056
ENSDART00000017202
kcnk1b
potassium channel, subfamily K, member 1b
chr23_-_17509656 0.48 ENSDART00000148423
dnajc5ab
DnaJ (Hsp40) homolog, subfamily C, member 5ab
chr12_+_33320504 0.47 ENSDART00000021491
csnk1db
casein kinase 1, delta b
chr13_-_38792061 0.45 ENSDART00000162858
lmbrd1
LMBR1 domain containing 1
chr23_+_34990693 0.45 ENSDART00000013449
CHST13
si:ch211-236h17.3
chr17_-_8674208 0.45 ENSDART00000149201
ctbp2a
C-terminal binding protein 2a
chr18_+_6558146 0.44 ENSDART00000169401
b4galnt3b
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr15_-_41689684 0.44 ENSDART00000143447
spsb4b
splA/ryanodine receptor domain and SOCS box containing 4b
chr10_+_14488625 0.44 ENSDART00000026383
sigmar1
sigma non-opioid intracellular receptor 1
chr4_-_2945306 0.44 ENSDART00000128934
ENSDART00000019518
aebp2
AE binding protein 2
chr18_+_25752592 0.43 ENSDART00000111767
si:ch211-39k3.2
si:ch211-39k3.2
chr5_+_58455488 0.43 ENSDART00000038602
ENSDART00000127958
slc37a2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr23_-_30764319 0.43 ENSDART00000075918
pcmtd2
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr3_-_18373604 0.43 ENSDART00000148132
spag9a
sperm associated antigen 9a
chr3_-_18373425 0.43 ENSDART00000178522
spag9a
sperm associated antigen 9a
chr20_+_25911342 0.42 ENSDART00000146004
ttbk2b
tau tubulin kinase 2b
chr15_-_5892650 0.42 ENSDART00000154812
brwd1
bromodomain and WD repeat domain containing 1
chr1_-_23595779 0.41 ENSDART00000134860
ENSDART00000138852
lcorl
ligand dependent nuclear receptor corepressor-like
chr3_-_21137362 0.41 ENSDART00000104051
cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr17_-_31212420 0.41 ENSDART00000086511
rpusd2
RNA pseudouridylate synthase domain containing 2
chr12_+_33894396 0.40 ENSDART00000130853
ENSDART00000152988
mfsd13a
major facilitator superfamily domain containing 13A
chr10_-_2971407 0.40 ENSDART00000132526
marveld2a
MARVEL domain containing 2a
chr7_+_66634167 0.38 ENSDART00000027616
eif4g2a
eukaryotic translation initiation factor 4, gamma 2a
chr18_+_6558338 0.38 ENSDART00000110892
b4galnt3b
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr24_-_12689571 0.37 ENSDART00000015517
pdcd6
programmed cell death 6
chr4_-_12930086 0.37 ENSDART00000013604
lemd3
LEM domain containing 3
chr15_-_23443588 0.36 ENSDART00000170427
ube4a
ubiquitination factor E4A (UFD2 homolog, yeast)
chr14_+_16093889 0.36 ENSDART00000159181
immt
inner membrane protein, mitochondrial (mitofilin)
chr25_+_18711804 0.35 ENSDART00000011149
fam185a
family with sequence similarity 185, member A
chr19_-_20106486 0.35 ENSDART00000043924
mpp6b
membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)
chr15_-_23443937 0.35 ENSDART00000148311
ube4a
ubiquitination factor E4A (UFD2 homolog, yeast)
chr19_-_32888758 0.34 ENSDART00000052080
laptm4b
lysosomal protein transmembrane 4 beta
chr13_+_18507592 0.34 ENSDART00000142622
si:ch211-198a12.6
si:ch211-198a12.6
chr9_-_27749936 0.33 ENSDART00000064156
tbccd1
TBCC domain containing 1
chr10_+_44903676 0.33 ENSDART00000158553
zgc:114173
zgc:114173
chr14_+_31493306 0.33 ENSDART00000138341
phf6
PHD finger protein 6
chr25_+_36045072 0.33 ENSDART00000126326
rpgrip1l
RPGRIP1-like
chr9_-_54840124 0.32 ENSDART00000137214
ENSDART00000085693
gpm6bb
glycoprotein M6Bb
chr11_-_2478374 0.32 ENSDART00000173205
si:ch73-267c23.10
si:ch73-267c23.10
chr5_+_36439405 0.29 ENSDART00000102973
eda
ectodysplasin A
chr14_+_31493119 0.28 ENSDART00000006463
phf6
PHD finger protein 6
chr2_+_30103131 0.28 ENSDART00000185119
dnajb6a
DnaJ (Hsp40) homolog, subfamily B, member 6a
chr22_-_4760187 0.28 ENSDART00000081969
rad23ab
RAD23 homolog A, nucleotide excision repair protein b
chr14_-_31619408 0.28 ENSDART00000173277
mmgt1
membrane magnesium transporter 1
chr23_-_29668286 0.28 ENSDART00000129248
clstn1
calsyntenin 1
chr17_-_9995667 0.28 ENSDART00000148463
snx6
sorting nexin 6
chr20_-_51727860 0.27 ENSDART00000147044
brox
BRO1 domain and CAAX motif containing
chr19_+_20163826 0.27 ENSDART00000090942
ENSDART00000134650
ccdc126
coiled-coil domain containing 126
chr14_-_52433292 0.26 ENSDART00000164272
rest
RE1-silencing transcription factor
chr23_-_20126257 0.25 ENSDART00000005021
tktb
transketolase b
chr10_+_28306749 0.25 ENSDART00000142016
ptrh2
peptidyl-tRNA hydrolase 2
chr15_-_1843831 0.23 ENSDART00000156718
ENSDART00000154175
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr6_+_12462079 0.23 ENSDART00000192029
ENSDART00000065385
nr4a2b
nuclear receptor subfamily 4, group A, member 2b
chr2_+_9560740 0.22 ENSDART00000003465
gipc2
GIPC PDZ domain containing family, member 2
chr21_+_43171013 0.21 ENSDART00000151362
zcchc10
zinc finger, CCHC domain containing 10
chr15_+_20239141 0.21 ENSDART00000101152
ENSDART00000152473
spint2
serine peptidase inhibitor, Kunitz type, 2
chr17_-_8673567 0.20 ENSDART00000192714
ENSDART00000012546
ctbp2a
C-terminal binding protein 2a
chr5_+_72145468 0.19 ENSDART00000148626
abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr23_-_10723009 0.19 ENSDART00000189721
foxp1a
forkhead box P1a
chr17_+_8184649 0.19 ENSDART00000091818
tulp4b
tubby like protein 4b
chr15_-_34845414 0.18 ENSDART00000009892
gabbr1a
gamma-aminobutyric acid (GABA) B receptor, 1a
chr1_-_55166511 0.17 ENSDART00000150430
ENSDART00000035725
pane1
proliferation associated nuclear element
chr2_+_9821757 0.16 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
anxa13l
annexin A13, like
chr25_-_34845302 0.16 ENSDART00000039485
gabarapl2
GABA(A) receptor-associated protein like 2
chr3_-_40284744 0.16 ENSDART00000018626
pdap1b
pdgfa associated protein 1b
chr1_-_23596391 0.15 ENSDART00000155184
lcorl
ligand dependent nuclear receptor corepressor-like
chr23_-_41824460 0.15 ENSDART00000131235
GMEB2
si:ch73-302a13.2
chr7_+_22616212 0.14 ENSDART00000052844
cldn7a
claudin 7a
chr23_-_10722664 0.14 ENSDART00000146526
ENSDART00000129022
ENSDART00000104985
foxp1a
forkhead box P1a
chr10_-_9089545 0.14 ENSDART00000080781
arl15b
ADP-ribosylation factor-like 15b
chr10_-_41906609 0.13 ENSDART00000102530
kdm2bb
lysine (K)-specific demethylase 2Bb
chr8_+_23147609 0.13 ENSDART00000180284
gid8a
GID complex subunit 8 homolog a (S. cerevisiae)
chr9_-_11655031 0.13 ENSDART00000044314
itgav
integrin, alpha V
chr11_+_40649412 0.13 ENSDART00000043016
ENSDART00000134560
slc45a1
solute carrier family 45, member 1
chr5_+_57715614 0.12 ENSDART00000037181
ufc1
ubiquitin-fold modifier conjugating enzyme 1
chr15_-_23721618 0.11 ENSDART00000109318
zc3h4
zinc finger CCCH-type containing 4
chr12_+_33894665 0.11 ENSDART00000004769
mfsd13a
major facilitator superfamily domain containing 13A
chr10_-_23099809 0.10 ENSDART00000148333
ENSDART00000079703
ENSDART00000162444
nle1
notchless homolog 1 (Drosophila)
chr8_+_49433663 0.10 ENSDART00000140481
ENSDART00000180714
nfu1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr13_+_646700 0.09 ENSDART00000006892
tp53bp2a
tumor protein p53 binding protein, 2a
chr15_-_34658057 0.09 ENSDART00000110964
bag6
BCL2 associated athanogene 6
chr13_-_36439061 0.08 ENSDART00000084867
dcaf5
ddb1 and cul4 associated factor 5
chr19_+_31904836 0.08 ENSDART00000162297
ENSDART00000088340
ENSDART00000151280
ENSDART00000151218
tpd52
tumor protein D52
chr19_+_28256076 0.08 ENSDART00000133354
irx4b
iroquois homeobox 4b
chr8_-_45838277 0.07 ENSDART00000046064
ogdha
oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide)
chr11_+_45255774 0.07 ENSDART00000172838
aspscr1
alveolar soft part sarcoma chromosome region, candidate 1
chr23_+_33963619 0.06 ENSDART00000140666
ENSDART00000084792
plpbp
pyridoxal phosphate binding protein
chr9_+_34148714 0.06 ENSDART00000078051
gpr161
G protein-coupled receptor 161
chr19_+_14113886 0.04 ENSDART00000169343
kdf1b
keratinocyte differentiation factor 1b
chr5_+_24128908 0.04 ENSDART00000029719
si:ch211-114c12.2
si:ch211-114c12.2
chr13_-_11971148 0.03 ENSDART00000066230
ENSDART00000185614
ARL3 (1 of many)
zgc:110197
chr23_+_17509794 0.03 ENSDART00000148457
gid8b
GID complex subunit 8 homolog b (S. cerevisiae)
chr7_-_12909352 0.03 ENSDART00000172901
sh3gl3a
SH3-domain GRB2-like 3a
chr3_-_15487111 0.02 ENSDART00000011320
nfatc2ip
nuclear factor of activated T cells 2 interacting protein
chr8_+_23147218 0.02 ENSDART00000030920
ENSDART00000141175
ENSDART00000146264
gid8a
GID complex subunit 8 homolog a (S. cerevisiae)
chr16_+_25137483 0.02 ENSDART00000155666
znf576.1
zinc finger protein 576, tandem duplicate 1
chr15_+_23443665 0.01 ENSDART00000059369
phykpl
5-phosphohydroxy-L-lysine phospho-lyase
chr23_+_17220986 0.00 ENSDART00000054761
nol4lb
nucleolar protein 4-like b

Network of associatons between targets according to the STRING database.

First level regulatory network of e4f1+si:dkeyp-79b7.12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.3 1.4 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.2 0.9 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.2 0.7 GO:0042908 xenobiotic transport(GO:0042908)
0.2 0.8 GO:0051182 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.2 0.7 GO:0051444 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.2 0.8 GO:0072575 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.2 1.5 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 1.6 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 2.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.3 GO:0051580 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.1 0.4 GO:0071788 endoplasmic reticulum tubular network maintenance(GO:0071788)
0.1 0.7 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.1 0.6 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.1 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.3 GO:0021785 branchiomotor neuron axon guidance(GO:0021785) negative regulation of cell maturation(GO:1903430)
0.1 0.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 1.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 0.3 GO:0051661 Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.1 0.5 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 0.8 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.4 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 0.5 GO:0030643 microglia differentiation(GO:0014004) cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320) cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.6 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.7 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.8 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.7 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.6 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.3 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.3 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.4 GO:0042407 cristae formation(GO:0042407)
0.0 0.4 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.8 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.6 GO:0055088 lipid homeostasis(GO:0055088)
0.0 1.0 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 1.9 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 1.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.4 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.8 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.6 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.8 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.7 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 0.1 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.5 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.6 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.4 GO:0008286 insulin receptor signaling pathway(GO:0008286)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 1.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.8 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.4 GO:0061689 tricellular tight junction(GO:0061689)
0.1 2.4 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 2.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.0 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.4 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.3 GO:0005771 multivesicular body(GO:0005771)
0.0 0.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.2 1.1 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.2 0.8 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 1.6 GO:0097001 sphingolipid binding(GO:0046625) ceramide binding(GO:0097001)
0.2 0.9 GO:0008432 JUN kinase binding(GO:0008432)
0.2 0.7 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.2 0.5 GO:0015562 inositol hexakisphosphate binding(GO:0000822) efflux transmembrane transporter activity(GO:0015562)
0.2 0.8 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.1 0.4 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 1.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.7 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.7 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 1.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 1.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.4 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 1.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.7 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.3 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 2.4 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.5 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0030546 death receptor binding(GO:0005123) receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.5 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 1.5 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0008515 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 1.4 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.9 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.6 GO:0042826 histone deacetylase binding(GO:0042826)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 0.8 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.2 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 4.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions