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PRJNA195909:zebrafish embryo and larva development

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Results for ebf3a-1+si:ch211-51e8.2

Z-value: 1.04

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Transcription factors associated with ebf3a-1+si:ch211-51e8.2

Gene Symbol Gene ID Gene Info
si_ch211-51e8.2
ENSDARG00000092635 si_ch211-51e8.2
ebf3a-1
ENSDARG00000099849 EBF transcription factor 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EBF1 (1 of many)dr11_v1_chr21_-_33995213_339952130.742.2e-02Click!
ebf3adr11_v1_chr14_+_35013656_35013656-0.713.2e-02Click!

Activity profile of ebf3a-1+si:ch211-51e8.2 motif

Sorted Z-values of ebf3a-1+si:ch211-51e8.2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_21471022 2.81 ENSDART00000104206
her4.2
hairy-related 4, tandem duplicate 2
chr22_+_11775269 2.75 ENSDART00000140272
krt96
keratin 96
chr22_+_11756040 2.67 ENSDART00000105808
krt97
keratin 97
chr25_+_31323978 2.12 ENSDART00000067030
lsp1
lymphocyte-specific protein 1
chr12_-_26406323 2.10 ENSDART00000131896
myoz1b
myozenin 1b
chr13_-_16226312 2.08 ENSDART00000163952
zgc:110045
zgc:110045
chr8_-_1051438 1.95 ENSDART00000067093
ENSDART00000170737
smyd1b
SET and MYND domain containing 1b
chr15_-_3736773 1.93 ENSDART00000090624
lpar6a
lysophosphatidic acid receptor 6a
chr11_+_41981959 1.87 ENSDART00000055707
her15.1
hairy and enhancer of split-related 15, tandem duplicate 1
chr21_+_26389391 1.84 ENSDART00000077197
tmsb
thymosin, beta
chr21_-_15929041 1.75 ENSDART00000080693
lhx5
LIM homeobox 5
chr7_-_52558495 1.55 ENSDART00000138263
ENSDART00000009938
ENSDART00000174292
ENSDART00000174218
ENSDART00000174335
tcf12
transcription factor 12
chr9_-_22831836 1.50 ENSDART00000142585
neb
nebulin
chr23_+_21459263 1.47 ENSDART00000104209
her4.3
hairy-related 4, tandem duplicate 3
chr2_+_56891858 1.41 ENSDART00000159912
zgc:85843
zgc:85843
chr15_-_3736149 1.38 ENSDART00000182986
lpar6a
lysophosphatidic acid receptor 6a
chr2_-_23172708 1.37 ENSDART00000041365
prrx1a
paired related homeobox 1a
chr11_-_37120954 1.36 ENSDART00000172074
NINJ1
si:ch1073-278o19.1
chr25_+_25453571 1.26 ENSDART00000112330
rassf7a
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7a
chr3_+_26081343 1.22 ENSDART00000134647
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr7_+_25920792 1.21 ENSDART00000026295
arrb2b
arrestin, beta 2b
chr7_-_56793739 1.19 ENSDART00000082842
si:ch211-146m13.3
si:ch211-146m13.3
chr11_-_23219367 1.17 ENSDART00000003646
optc
opticin
chr4_-_16345227 1.14 ENSDART00000079521
kera
keratocan
chr1_-_59411901 1.11 ENSDART00000167015
si:ch211-188p14.4
si:ch211-188p14.4
chr19_+_19786117 1.11 ENSDART00000167757
ENSDART00000163546
hoxa1a
homeobox A1a
chr10_-_29101715 1.07 ENSDART00000149674
ENSDART00000171194
ENSDART00000192019
si:ch211-103f14.3
si:ch211-103f14.3
chr6_+_54711306 1.06 ENSDART00000074605
pkp1b
plakophilin 1b
chr3_-_30158395 1.05 ENSDART00000103502
si:ch211-152f23.5
si:ch211-152f23.5
chr1_-_35924495 1.05 ENSDART00000184424
smad1
SMAD family member 1
chr16_-_7228276 1.01 ENSDART00000149030
nt5c3a
5'-nucleotidase, cytosolic IIIA
chr19_+_19756425 1.01 ENSDART00000167606
hoxa3a
homeobox A3a
chr19_+_58954 0.94 ENSDART00000162379
col14a1b
collagen, type XIV, alpha 1b
chr19_+_56351 0.94 ENSDART00000168334
col14a1b
collagen, type XIV, alpha 1b
chr10_-_31563049 0.92 ENSDART00000023575
robo3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr20_-_23439011 0.91 ENSDART00000022887
slc10a4
solute carrier family 10, member 4
chr7_-_18554603 0.91 ENSDART00000108938
msantd1
Myb/SANT-like DNA-binding domain containing 1
chr24_-_23942722 0.89 ENSDART00000080810
arxa
aristaless related homeobox a
chr12_+_25945560 0.88 ENSDART00000109799
mmrn2b
multimerin 2b
chr12_-_431249 0.87 ENSDART00000083827
hs3st3l
heparan sulfate (glucosamine) 3-O-sulfotransferase 3-like
chr10_+_158590 0.85 ENSDART00000081982
KCNJ15
potassium voltage-gated channel subfamily J member 15
chr22_+_28446365 0.84 ENSDART00000189359
abi3bpb
ABI family, member 3 (NESH) binding protein b
chr15_-_24869826 0.82 ENSDART00000127047
tusc5a
tumor suppressor candidate 5a
chr12_+_45677293 0.78 ENSDART00000152850
ENSDART00000153047
si:ch73-111m19.2
si:ch73-111m19.2
chr15_+_1372343 0.78 ENSDART00000152285
schip1
schwannomin interacting protein 1
chr15_-_2184638 0.77 ENSDART00000135460
shox2
short stature homeobox 2
chr9_-_21912227 0.76 ENSDART00000145576
lmo7a
LIM domain 7a
chr20_-_53321499 0.76 ENSDART00000179894
ENSDART00000127427
ENSDART00000084952
wasf1
WAS protein family, member 1
chr20_+_27020201 0.75 ENSDART00000126919
ENSDART00000016014
chga
chromogranin A
chr14_-_6727717 0.74 ENSDART00000166979
si:dkeyp-44a8.4
si:dkeyp-44a8.4
chr25_-_24074500 0.72 ENSDART00000040410
th
tyrosine hydroxylase
chr22_+_661711 0.72 ENSDART00000113795
elf3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr17_-_21441464 0.72 ENSDART00000031490
vax1
ventral anterior homeobox 1
chr19_+_10979983 0.72 ENSDART00000142975
si:ch1073-70f20.1
si:ch1073-70f20.1
chr9_+_44431174 0.71 ENSDART00000149726
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr2_+_22495274 0.70 ENSDART00000167915
lrrc8da
leucine rich repeat containing 8 VRAC subunit Da
chr13_-_9318891 0.69 ENSDART00000137364
si:dkey-33c12.3
si:dkey-33c12.3
chr5_-_5831037 0.69 ENSDART00000112856
zmp:0000000846
zmp:0000000846
chr13_+_12045758 0.68 ENSDART00000079398
ENSDART00000165467
ENSDART00000165880
gng2
guanine nucleotide binding protein (G protein), gamma 2
chr17_+_37645633 0.68 ENSDART00000085500
tmem229b
transmembrane protein 229B
chr19_-_35596207 0.67 ENSDART00000136811
col8a2
collagen, type VIII, alpha 2
chr15_+_59417 0.65 ENSDART00000187260
AXL
AXL receptor tyrosine kinase
chr6_-_8264751 0.64 ENSDART00000091628
ccdc151
coiled-coil domain containing 151
chr7_-_41489997 0.64 ENSDART00000174300
smarcd3b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr22_-_30881738 0.64 ENSDART00000059965
si:dkey-49n23.1
si:dkey-49n23.1
chr14_-_16328331 0.62 ENSDART00000111262
pcdh12
protocadherin 12
chr4_-_58964138 0.62 ENSDART00000150259
si:ch211-64i20.3
si:ch211-64i20.3
chr9_+_41612642 0.61 ENSDART00000138473
spegb
SPEG complex locus b
chr10_-_27199135 0.59 ENSDART00000189511
ENSDART00000180314
auts2a
autism susceptibility candidate 2a
chr8_+_30671060 0.59 ENSDART00000193749
adora2aa
adenosine A2a receptor a
chr10_+_35422802 0.58 ENSDART00000147303
hhla2a.1
HERV-H LTR-associating 2a, tandem duplicate 1
chr19_-_2421793 0.57 ENSDART00000180238
TMEM196 (1 of many)
transmembrane protein 196
chr8_-_15182232 0.57 ENSDART00000138855
bcar3
BCAR3, NSP family adaptor protein
chr2_-_30987538 0.56 ENSDART00000148157
emilin2a
elastin microfibril interfacer 2a
chr23_+_26946744 0.56 ENSDART00000115141
cacnb3b
calcium channel, voltage-dependent, beta 3b
chr19_-_26863626 0.55 ENSDART00000145568
prrt1
proline-rich transmembrane protein 1
chr6_+_58406014 0.54 ENSDART00000044241
kcnq2b
potassium voltage-gated channel, KQT-like subfamily, member 2b
chr14_-_21959712 0.54 ENSDART00000021417
p2rx3a
purinergic receptor P2X, ligand-gated ion channel, 3a
chr9_+_44430974 0.53 ENSDART00000056846
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr4_+_11375894 0.53 ENSDART00000190471
ENSDART00000143963
pcloa
piccolo presynaptic cytomatrix protein a
chr6_-_56111829 0.53 ENSDART00000154397
gcnt7
glucosaminyl (N-acetyl) transferase family member 7
chr20_-_47732703 0.53 ENSDART00000193975
tfap2d
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr23_+_20931030 0.52 ENSDART00000167014
pax7b
paired box 7b
chr1_-_40994259 0.51 ENSDART00000101562
adra2c
adrenoceptor alpha 2C
chr7_+_66822229 0.50 ENSDART00000112109
lyve1a
lymphatic vessel endothelial hyaluronic receptor 1a
chr21_-_43482426 0.49 ENSDART00000192901
ankrd46a
ankyrin repeat domain 46a
chr20_-_49657134 0.49 ENSDART00000151248
col12a1b
collagen, type XII, alpha 1b
chr2_-_4868002 0.49 ENSDART00000189835
tfr1a
transferrin receptor 1a
chr23_+_19814371 0.48 ENSDART00000182897
emd
emerin (Emery-Dreifuss muscular dystrophy)
chr14_-_858985 0.47 ENSDART00000148687
ENSDART00000149375
slc34a1a
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1a
chr13_-_47800342 0.47 ENSDART00000121817
fbln7
fibulin 7
chr15_-_34214440 0.46 ENSDART00000167052
etv1
ets variant 1
chr16_-_36834505 0.45 ENSDART00000141275
ENSDART00000139588
ENSDART00000041993
pnp4b
purine nucleoside phosphorylase 4b
chr23_+_40460333 0.45 ENSDART00000184658
soga3b
SOGA family member 3b
chr24_+_1294176 0.42 ENSDART00000106637
si:ch73-134f24.1
si:ch73-134f24.1
chr4_+_20263097 0.42 ENSDART00000138820
lrtm2a
leucine-rich repeats and transmembrane domains 2a
chr12_-_7807298 0.40 ENSDART00000191355
ank3b
ankyrin 3b
chr1_+_54835131 0.40 ENSDART00000145070
si:ch211-196h16.4
si:ch211-196h16.4
chr1_-_44701313 0.39 ENSDART00000193926
si:dkey-28b4.8
si:dkey-28b4.8
chr14_-_2196267 0.39 ENSDART00000161674
ENSDART00000125674
pcdh2ab8
pcdh2ab9
protocadherin 2 alpha b 8
protocadherin 2 alpha b 9
chr6_+_55277419 0.38 ENSDART00000083670
CABZ01041604.1

chr11_+_2156430 0.38 ENSDART00000182896
hoxc13b
homeobox C13b
chr15_+_37559570 0.38 ENSDART00000085522
hspb6
heat shock protein, alpha-crystallin-related, b6
chr13_-_49819027 0.37 ENSDART00000067824
b3galnt2
beta-1,3-N-acetylgalactosaminyltransferase 2
chr22_+_567733 0.36 ENSDART00000171036
usp49
ubiquitin specific peptidase 49
chr3_-_3496738 0.36 ENSDART00000186849
CABZ01040998.1

chr14_+_41887070 0.36 ENSDART00000173264
slc7a11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr3_-_11203689 0.36 ENSDART00000166328
BX323882.1

chr8_+_8936912 0.36 ENSDART00000135958
si:dkey-83k24.5
si:dkey-83k24.5
chr22_-_32360464 0.35 ENSDART00000148886
pcbp4
poly(rC) binding protein 4
chr16_+_40563533 0.35 ENSDART00000190368
tp53inp1
tumor protein p53 inducible nuclear protein 1
chr18_-_21177674 0.35 ENSDART00000060175
si:dkey-12e7.4
si:dkey-12e7.4
chr23_-_16692312 0.35 ENSDART00000046784
fkbp1ab
FK506 binding protein 1Ab
chr4_+_15819728 0.34 ENSDART00000101613
lrguk
leucine-rich repeats and guanylate kinase domain containing
chr14_+_25817628 0.33 ENSDART00000047680
glra1
glycine receptor, alpha 1
chr9_-_45149695 0.33 ENSDART00000162033
CU467837.1

chr16_-_49846359 0.33 ENSDART00000184246
znf385d
zinc finger protein 385D
chr17_-_22324727 0.32 ENSDART00000160341
CU104709.1

chr10_-_27049170 0.32 ENSDART00000143451
cnih2
cornichon family AMPA receptor auxiliary protein 2
chr21_+_10756154 0.32 ENSDART00000074833
rx3
retinal homeobox gene 3
chr16_-_25606889 0.31 ENSDART00000077447
ENSDART00000131528
zgc:110410
zgc:110410
chr4_+_4272622 0.31 ENSDART00000164810
ano2
anoctamin 2
chr12_+_30360579 0.30 ENSDART00000152900
si:ch211-225b10.3
si:ch211-225b10.3
chr11_+_807153 0.30 ENSDART00000173289
vgll4b
vestigial-like family member 4b
chr8_+_25342896 0.30 ENSDART00000129032
CR847543.1

chr8_-_34762163 0.29 ENSDART00000114080
setd1bb
SET domain containing 1B, b
chr18_-_7112882 0.29 ENSDART00000176292
si:dkey-88e18.8
si:dkey-88e18.8
chr7_+_11459235 0.29 ENSDART00000159611
il16
interleukin 16
chr13_-_40316367 0.29 ENSDART00000009343
pyroxd2
pyridine nucleotide-disulphide oxidoreductase domain 2
chr18_+_34225520 0.29 ENSDART00000126115
v2rl1
vomeronasal 2 receptor, l1
chr22_-_27136451 0.29 ENSDART00000153589
si:dkey-16m19.1
si:dkey-16m19.1
chr2_-_32457919 0.28 ENSDART00000132792
ENSDART00000041319
slc4a2a
solute carrier family 4 (anion exchanger), member 2a
chr19_+_5651325 0.28 ENSDART00000082067
ft1
alpha(1,3)fucosyltransferase gene 1
chr16_-_19254323 0.28 ENSDART00000138744
dnah11
dynein, axonemal, heavy chain 11
chr14_+_25817246 0.28 ENSDART00000136733
glra1
glycine receptor, alpha 1
chr21_-_11820379 0.28 ENSDART00000126640
RHOBTB3
si:dkey-6b12.5
chr2_-_37896646 0.26 ENSDART00000075931
hbl1
hexose-binding lectin 1
chr4_-_20115570 0.26 ENSDART00000134528
si:dkey-159a18.1
si:dkey-159a18.1
chr2_-_37465517 0.26 ENSDART00000139983
si:dkey-57k2.6
si:dkey-57k2.6
chr1_-_46989650 0.26 ENSDART00000129072
ENSDART00000150507
si:dkey-22n8.3
si:dkey-22n8.3
chr24_+_3050020 0.25 ENSDART00000004241
inhbaa
inhibin, beta Aa
chr15_+_16521785 0.25 ENSDART00000062191
galnt17
polypeptide N-acetylgalactosaminyltransferase 17
chr5_+_43870389 0.24 ENSDART00000141002
zgc:112966
zgc:112966
chr23_+_26946429 0.24 ENSDART00000185564
cacnb3b
calcium channel, voltage-dependent, beta 3b
chr5_-_38161033 0.24 ENSDART00000145907
gucy2d
guanylate cyclase 2D, retinal
chr7_-_24005268 0.23 ENSDART00000173608
si:dkey-183c6.9
si:dkey-183c6.9
chr8_-_3716734 0.23 ENSDART00000172966
bicdl1
BICD family like cargo adaptor 1
chr25_-_1235457 0.23 ENSDART00000093093
coro2bb
coronin, actin binding protein, 2Bb
chr13_+_29193649 0.23 ENSDART00000045951
unc5b
unc-5 netrin receptor B
chr1_-_17675037 0.22 ENSDART00000142689
si:dkey-256e7.5
si:dkey-256e7.5
chr15_+_5321612 0.22 ENSDART00000174345
or113-1
odorant receptor, family A, subfamily 113, member 1
chr25_+_35212919 0.22 ENSDART00000180127
ano5a
anoctamin 5a
chr12_+_34763795 0.22 ENSDART00000153097
slc38a10
solute carrier family 38, member 10
chr7_+_34487833 0.21 ENSDART00000173854
cln6a
CLN6, transmembrane ER protein a
chr22_-_9618867 0.19 ENSDART00000131246
si:ch73-286h23.4
si:ch73-286h23.4
chr21_-_11791909 0.19 ENSDART00000180893
RHOBTB3
si:dkey-6b12.5
chr17_-_33407843 0.17 ENSDART00000129416
BX323819.1

chr5_+_38900249 0.17 ENSDART00000097856
fras1
Fraser extracellular matrix complex subunit 1
chr25_+_13157165 0.16 ENSDART00000155653
si:dkeyp-50b9.1
si:dkeyp-50b9.1
chr10_+_43039947 0.16 ENSDART00000193434
atg10
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr12_-_46176115 0.15 ENSDART00000152848
si:ch211-226h7.8
si:ch211-226h7.8
chr4_+_58240778 0.15 ENSDART00000181184
ENSDART00000192348
ENSDART00000189444
ENSDART00000164424
si:dkey-16p6.1
si:dkey-16p6.1
chr20_-_25669813 0.13 ENSDART00000153118
si:dkeyp-117h8.2
si:dkeyp-117h8.2
chr21_-_24632778 0.13 ENSDART00000132533
ENSDART00000058370
arhgap32b
Rho GTPase activating protein 32b
chr12_-_43693192 0.13 ENSDART00000172284
CU914622.1

chr15_+_35718354 0.13 ENSDART00000110003
nyap2a
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2a
chr7_+_73807504 0.12 ENSDART00000166244
si:ch73-252p3.1
si:ch73-252p3.1
chr8_+_48858132 0.12 ENSDART00000124737
ENSDART00000079644
tp73
tumor protein p73
chr4_+_5193198 0.12 ENSDART00000067388
fgf23
fibroblast growth factor 23
chr6_+_40794015 0.12 ENSDART00000144479
gata2b
GATA binding protein 2b
chr7_-_52334840 0.11 ENSDART00000174173
CR938716.1

chr11_+_6159595 0.11 ENSDART00000178367
slc1a6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr21_+_21685228 0.11 ENSDART00000142844
or125-4
odorant receptor, family E, subfamily 125, member 4
chr20_-_2725930 0.11 ENSDART00000081643
akirin2
akirin 2
chr23_-_36418059 0.10 ENSDART00000135232
znf740b
zinc finger protein 740b
chr2_-_52020049 0.10 ENSDART00000128198
ENSDART00000135331
scn12aa
sodium channel, voltage gated, type XII, alpha a
chr3_+_32118670 0.09 ENSDART00000055287
ENSDART00000111688
zgc:109934
zgc:109934
chr2_-_23541059 0.09 ENSDART00000133908
si:dkey-58b18.3
si:dkey-58b18.3
chr17_-_24439672 0.09 ENSDART00000155020
wdpcp
WD repeat containing planar cell polarity effector
chr11_-_8271374 0.09 ENSDART00000168253
pimr202
Pim proto-oncogene, serine/threonine kinase, related 202
chr16_-_45854882 0.08 ENSDART00000027013
ENSDART00000128068
ntrk1
neurotrophic tyrosine kinase, receptor, type 1
chr15_-_5157572 0.08 ENSDART00000174192
or128-10
odorant receptor, family E, subfamily 128, member 10
chr16_-_30927764 0.08 ENSDART00000156804
slc45a4
solute carrier family 45, member 4
chr23_-_1144425 0.08 ENSDART00000098271
psmb11b
proteasome subunit beta11b
chr18_+_20031046 0.08 ENSDART00000132656
rxfp3.3a3
relaxin/insulin-like family peptide receptor 3.3a3
chr18_+_33468099 0.07 ENSDART00000131769
v2rh9
vomeronasal 2 receptor, h9
chr1_-_191971 0.07 ENSDART00000164091
ENSDART00000159237
grtp1a
growth hormone regulated TBC protein 1a
chr4_-_72513569 0.07 ENSDART00000174130
CR788316.4

chr1_-_54191626 0.06 ENSDART00000062941
nthl1
nth-like DNA glycosylase 1
chr16_-_47483142 0.06 ENSDART00000147072
cthrc1b
collagen triple helix repeat containing 1b
chr25_+_9003230 0.06 ENSDART00000180330
ENSDART00000142917
rag1
recombination activating gene 1
chr4_-_9579299 0.05 ENSDART00000183079
ENSDART00000192968
ENSDART00000091809
shank3b
SH3 and multiple ankyrin repeat domains 3b
chr18_+_33340868 0.05 ENSDART00000099139
v2rh14
vomeronasal 2 receptor, h14
chr10_-_5022176 0.05 ENSDART00000148277
hnrnpdl
heterogeneous nuclear ribonucleoprotein D-like
chr22_-_9677264 0.04 ENSDART00000181737
si:dkey-286j17.4
si:dkey-286j17.4
chr22_-_18387059 0.04 ENSDART00000007769
tssk6
testis-specific serine kinase 6
chr6_+_2951645 0.04 ENSDART00000183181
ENSDART00000181271
ptprfa
protein tyrosine phosphatase, receptor type, f, a
chr6_+_11850359 0.04 ENSDART00000109552
ENSDART00000188139
ENSDART00000181499
ENSDART00000178269
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr16_-_25607266 0.03 ENSDART00000192602
zgc:110410
zgc:110410
chr2_-_23603061 0.03 ENSDART00000132072
si:dkey-58b18.9
si:dkey-58b18.9

Network of associatons between targets according to the STRING database.

First level regulatory network of ebf3a-1+si:ch211-51e8.2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.3 1.2 GO:0045988 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.3 1.2 GO:1900120 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.2 0.7 GO:0090278 negative regulation of peptide secretion(GO:0002792) relaxation of muscle(GO:0090075) negative regulation of peptide hormone secretion(GO:0090278)
0.2 1.5 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.2 0.7 GO:0042416 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.2 0.9 GO:0003322 pancreatic A cell development(GO:0003322)
0.2 0.6 GO:0071361 cellular response to ethanol(GO:0071361)
0.2 4.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.2 1.9 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.2 0.9 GO:0051701 interaction with host(GO:0051701)
0.2 1.4 GO:0086002 cardiac muscle cell action potential involved in contraction(GO:0086002)
0.2 1.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.6 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 1.0 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.8 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 0.5 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.1 0.3 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.1 0.5 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.1 0.5 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.1 0.7 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.1 0.1 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.1 3.3 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.6 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.4 GO:0048025 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 0.9 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.9 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.1 GO:0072502 cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320) cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.2 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.1 0.6 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.5 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.8 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.5 GO:0033198 response to ATP(GO:0033198)
0.0 0.3 GO:0050930 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.0 0.6 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.4 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.6 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.5 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 1.3 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.3 GO:0036065 fucosylation(GO:0036065)
0.0 0.1 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.7 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.5 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.0 1.0 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 1.9 GO:0001756 somitogenesis(GO:0001756)
0.0 1.7 GO:0030900 forebrain development(GO:0030900)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.4 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0031673 H zone(GO:0031673)
0.1 2.6 GO:0031430 M band(GO:0031430)
0.1 0.5 GO:0043194 axon initial segment(GO:0043194)
0.1 0.7 GO:0042583 chromaffin granule(GO:0042583)
0.1 1.7 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 6.1 GO:0005882 intermediate filament(GO:0005882)
0.1 1.1 GO:0030057 desmosome(GO:0030057)
0.1 0.5 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 1.0 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.8 GO:0031209 SCAR complex(GO:0031209)
0.0 0.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 3.2 GO:0030018 Z disc(GO:0030018)
0.0 1.3 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0097541 axonemal basal plate(GO:0097541)
0.0 0.5 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.5 GO:0005903 brush border(GO:0005903)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.2 3.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 2.1 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.2 0.9 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.5 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.9 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 1.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.8 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.5 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 1.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.6 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.7 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.5 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.6 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.2 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 1.0 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.5 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 1.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.5 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.0 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 7.6 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 1.0 PID ALK2 PATHWAY ALK2 signaling events
0.1 2.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 0.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.6 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation