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PRJNA195909:zebrafish embryo and larva development

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Results for egr2a+egr2b

Z-value: 0.67

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Transcription factors associated with egr2a+egr2b

Gene Symbol Gene ID Gene Info
egr2b
ENSDARG00000042826 early growth response 2b
egr2a
ENSDARG00000044098 early growth response 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
egr2bdr11_v1_chr12_-_8504278_85042780.068.7e-01Click!
egr2adr11_v1_chr17_-_43666166_43666166-0.058.9e-01Click!

Activity profile of egr2a+egr2b motif

Sorted Z-values of egr2a+egr2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_29556844 0.94 ENSDART00000138021
rbp7a
retinol binding protein 7a, cellular
chr8_-_53490376 0.81 ENSDART00000158789
chdh
choline dehydrogenase
chr6_-_39313027 0.74 ENSDART00000012644
krt4
keratin 4
chr3_+_32492467 0.74 ENSDART00000151329
trpm4a
transient receptor potential cation channel, subfamily M, member 4a
chr11_+_1796426 0.72 ENSDART00000173330
lrp1aa
low density lipoprotein receptor-related protein 1Aa
chr6_-_15604417 0.64 ENSDART00000157817
lrrfip1b
leucine rich repeat (in FLII) interacting protein 1b
chr14_+_7939398 0.55 ENSDART00000189773
cxxc5b
CXXC finger protein 5b
chr1_-_7659870 0.53 ENSDART00000085203
efnb2b
ephrin-B2b
chr3_-_39488482 0.53 ENSDART00000135192
zgc:100868
zgc:100868
chr3_-_6767440 0.52 ENSDART00000156174
mast1b
microtubule associated serine/threonine kinase 1b
chr7_-_58776400 0.51 ENSDART00000167433
sox17
SRY (sex determining region Y)-box 17
chr23_+_20422661 0.51 ENSDART00000144047
ENSDART00000104336
tnnc2
troponin C type 2 (fast)
chr23_+_25856541 0.50 ENSDART00000145426
ENSDART00000028236
hnf4a
hepatocyte nuclear factor 4, alpha
chr17_-_52643970 0.50 ENSDART00000190594
spred1
sprouty-related, EVH1 domain containing 1
chr3_-_39488639 0.48 ENSDART00000161644
zgc:100868
zgc:100868
chr8_-_51753604 0.48 ENSDART00000007090
tbx16
T-box 16
chr25_-_29134654 0.48 ENSDART00000067066
parp6b
poly (ADP-ribose) polymerase family, member 6b
chr5_+_51026563 0.47 ENSDART00000050988
gcnt4a
glucosaminyl (N-acetyl) transferase 4, core 2, a
chr12_-_30777540 0.47 ENSDART00000126466
entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr15_-_16012963 0.46 ENSDART00000144138
hnf1ba
HNF1 homeobox Ba
chr10_+_10351685 0.46 ENSDART00000109432
cercam
cerebral endothelial cell adhesion molecule
chr16_+_40575742 0.45 ENSDART00000161503
ccne2
cyclin E2
chr6_+_56147812 0.44 ENSDART00000150219
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr12_+_11080776 0.44 ENSDART00000079336
raraa
retinoic acid receptor, alpha a
chr12_+_695619 0.42 ENSDART00000161691
abcc3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr3_+_12322170 0.41 ENSDART00000161227
glis2b
GLIS family zinc finger 2b
chr23_+_37815645 0.41 ENSDART00000011627
irx7
iroquois homeobox 7
chr12_-_30777743 0.41 ENSDART00000148888
entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr7_-_29534001 0.41 ENSDART00000124028
anxa2b
annexin A2b
chr23_-_39849155 0.41 ENSDART00000115330
ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr5_-_57655092 0.40 ENSDART00000074290
mia
melanoma inhibitory activity
chr14_+_36220479 0.39 ENSDART00000148319
pitx2
paired-like homeodomain 2
chr7_-_33023404 0.38 ENSDART00000052383
cd81a
CD81 molecule a
chr16_-_26676685 0.38 ENSDART00000103431
esrp1
epithelial splicing regulatory protein 1
chr1_-_411331 0.38 ENSDART00000092524
rasa3
RAS p21 protein activator 3
chr16_-_6821927 0.38 ENSDART00000149070
ENSDART00000149570
mbpb
myelin basic protein b
chr2_+_33326522 0.37 ENSDART00000056655
klf17
Kruppel-like factor 17
chr11_-_7139555 0.36 ENSDART00000016472
bmp7a
bone morphogenetic protein 7a
chr10_+_38643304 0.36 ENSDART00000067447
mmp30
matrix metallopeptidase 30
chr14_+_909769 0.36 ENSDART00000021346
ENSDART00000172777
arl3l2
ADP-ribosylation factor-like 3, like 2
chr21_+_53504 0.36 ENSDART00000170452
dmgdh
dimethylglycine dehydrogenase
chr16_+_23978978 0.34 ENSDART00000058964
ENSDART00000135084
apoa2
apolipoprotein A-II
chr2_+_26288301 0.34 ENSDART00000017668
ptbp1a
polypyrimidine tract binding protein 1a
chr11_+_24251141 0.34 ENSDART00000182684
pnp4a
purine nucleoside phosphorylase 4a
chr8_-_52859301 0.33 ENSDART00000162004
nr5a1a
nuclear receptor subfamily 5, group A, member 1a
chr9_-_9671244 0.33 ENSDART00000018228
gsk3b
glycogen synthase kinase 3 beta
chr24_+_35564668 0.32 ENSDART00000122734
cebpd
CCAAT/enhancer binding protein (C/EBP), delta
chr25_-_18125769 0.32 ENSDART00000140484
kitlga
kit ligand a
chr7_-_5125799 0.32 ENSDART00000173390
ltb4r2a
leukotriene B4 receptor 2a
chr5_+_36513605 0.31 ENSDART00000013590
wnt11
wingless-type MMTV integration site family, member 11
chr20_+_37844035 0.31 ENSDART00000041397
flvcr1
feline leukemia virus subgroup C cellular receptor 1
chr16_+_13424534 0.30 ENSDART00000114944
zgc:101640
zgc:101640
chr5_+_22969651 0.30 ENSDART00000089992
ENSDART00000145477
hmgn7
high mobility group nucleosomal binding domain 7
chr5_-_40510397 0.30 ENSDART00000146237
ENSDART00000051065
fsta
follistatin a
chr10_-_15053507 0.30 ENSDART00000157446
ENSDART00000170441
CLDN23
si:ch211-95j8.5
chr4_+_30775376 0.30 ENSDART00000158528
si:dkey-11d20.1
si:dkey-11d20.1
chr19_-_31341850 0.29 ENSDART00000040810
arl4ab
ADP-ribosylation factor-like 4ab
chr20_+_13894123 0.29 ENSDART00000007744
slc30a1a
solute carrier family 30 (zinc transporter), member 1a
chr15_+_46344655 0.29 ENSDART00000155893
si:ch1073-340i21.2
si:ch1073-340i21.2
chr20_-_53366137 0.28 ENSDART00000146001
wasf1
WAS protein family, member 1
chr5_+_32791245 0.28 ENSDART00000077189
ier5l
immediate early response 5-like
chr6_-_15604157 0.28 ENSDART00000141597
lrrfip1b
leucine rich repeat (in FLII) interacting protein 1b
chr16_+_51180938 0.28 ENSDART00000169022
hmgn2
high mobility group nucleosomal binding domain 2
chr19_+_43119698 0.28 ENSDART00000167847
ENSDART00000186962
ENSDART00000187305
eef1a1l1
eukaryotic translation elongation factor 1 alpha 1, like 1
chr9_-_33121535 0.28 ENSDART00000166371
ENSDART00000138052
zgc:172014
zgc:172014
chr7_-_26408472 0.28 ENSDART00000111494
gal3st4
galactose-3-O-sulfotransferase 4
chr2_-_22535 0.28 ENSDART00000157877
CABZ01092282.1

chr23_+_23232136 0.27 ENSDART00000126479
ENSDART00000187764
plekhn1
pleckstrin homology domain containing, family N member 1
chr18_-_3166726 0.27 ENSDART00000165002
aqp11
aquaporin 11
chr17_+_27456804 0.26 ENSDART00000017756
ENSDART00000181461
ENSDART00000180178
ctsl.1
cathepsin L.1
chr23_+_39606108 0.26 ENSDART00000109464
g0s2
G0/G1 switch 2
chr23_-_637347 0.26 ENSDART00000132175
l1camb
L1 cell adhesion molecule, paralog b
chr16_+_4658250 0.26 ENSDART00000006212
LIN28A
si:ch1073-284b18.2
chr20_-_26420939 0.25 ENSDART00000110883
akap12b
A kinase (PRKA) anchor protein 12b
chr14_+_29769336 0.25 ENSDART00000105898
si:dkey-34l15.1
si:dkey-34l15.1
chr19_-_617246 0.25 ENSDART00000062551
cyp51
cytochrome P450, family 51
chr13_+_25428677 0.25 ENSDART00000186284
si:dkey-51a16.9
si:dkey-51a16.9
chr18_+_22109379 0.25 ENSDART00000147230
zgc:158868
zgc:158868
chr20_-_26421112 0.25 ENSDART00000183767
ENSDART00000182330
akap12b
A kinase (PRKA) anchor protein 12b
chr6_-_35446110 0.25 ENSDART00000058773
rgs16
regulator of G protein signaling 16
chr4_+_1600034 0.25 ENSDART00000146779
slc38a2
solute carrier family 38, member 2
chr16_-_12512568 0.24 ENSDART00000055161
ENSDART00000160906
cox6b2
cytochrome c oxidase subunit VIb polypeptide 2
chr23_-_2081554 0.24 ENSDART00000179805
ndnf
neuron-derived neurotrophic factor
chr19_+_1964005 0.24 ENSDART00000172049
sh3bp5a
SH3-domain binding protein 5a (BTK-associated)
chr15_+_42397125 0.23 ENSDART00000169751
tiam1b
T cell lymphoma invasion and metastasis 1b
chr9_+_17348745 0.23 ENSDART00000147488
slain1a
SLAIN motif family, member 1a
chr8_+_25267903 0.23 ENSDART00000093090
ampd2b
adenosine monophosphate deaminase 2b
chr20_+_52554352 0.23 ENSDART00000153217
ENSDART00000145230
eef1db
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr23_+_9560797 0.23 ENSDART00000180014
adrm1
adhesion regulating molecule 1
chr16_+_28754403 0.23 ENSDART00000103340
s100v1
S100 calcium binding protein V1
chr8_+_34731982 0.23 ENSDART00000066050
hpdb
4-hydroxyphenylpyruvate dioxygenase b
chr6_-_16406210 0.22 ENSDART00000012023
faimb
Fas apoptotic inhibitory molecule b
chr5_+_68807170 0.22 ENSDART00000017849
her7
hairy and enhancer of split related-7
chr11_+_3254524 0.22 ENSDART00000159459
pmela
premelanosome protein a
chr19_+_10493223 0.22 ENSDART00000180826
si:ch211-171h4.6
si:ch211-171h4.6
chr20_-_9760424 0.22 ENSDART00000104936
si:dkey-63j12.4
si:dkey-63j12.4
chr23_+_9560991 0.22 ENSDART00000081433
ENSDART00000131594
ENSDART00000130069
ENSDART00000138601
adrm1
adhesion regulating molecule 1
chr18_+_30028135 0.22 ENSDART00000140825
ENSDART00000145306
ENSDART00000136810
si:ch211-220f16.1
si:ch211-220f16.1
chr11_-_33919309 0.22 ENSDART00000078202
phka2
phosphorylase kinase, alpha 2 (liver)
chr7_-_10560964 0.22 ENSDART00000172761
ENSDART00000170476
mthfs
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr20_-_45661049 0.21 ENSDART00000124582
ENSDART00000131251
napbb
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr23_-_2513300 0.21 ENSDART00000067652
snai1b
snail family zinc finger 1b
chr13_+_12739283 0.21 ENSDART00000102279
lingo2b
leucine rich repeat and Ig domain containing 2b
chr4_-_9173552 0.21 ENSDART00000042963
chst11
carbohydrate (chondroitin 4) sulfotransferase 11
chr13_-_15865335 0.21 ENSDART00000135186
si:ch211-57f7.7
si:ch211-57f7.7
chr15_+_1397811 0.21 ENSDART00000102125
schip1
schwannomin interacting protein 1
chr12_+_23762966 0.21 ENSDART00000152942
ENSDART00000181725
jcada
junctional cadherin 5 associated a
chr1_+_55293424 0.21 ENSDART00000152464
zgc:172106
zgc:172106
chr25_-_33275666 0.20 ENSDART00000193605
CABZ01046954.1

chr25_-_23526058 0.20 ENSDART00000191331
ENSDART00000062930
phlda2
pleckstrin homology-like domain, family A, member 2
chr9_+_3035128 0.20 ENSDART00000140693
si:ch211-173m16.2
si:ch211-173m16.2
chr23_+_42338325 0.20 ENSDART00000169660
cyp2aa7
cytochrome P450, family 2, subfamily AA, polypeptide 7
chr2_-_17828279 0.20 ENSDART00000083314
ptprfb
protein tyrosine phosphatase, receptor type, f, b
chr25_+_1304173 0.20 ENSDART00000155229
rxfp3.3b
relaxin/insulin-like family peptide receptor 3.3b
chr21_+_28958471 0.20 ENSDART00000144331
ENSDART00000005929
ppp3ca
protein phosphatase 3, catalytic subunit, alpha isozyme
chr14_+_31865324 0.20 ENSDART00000039880
tm9sf5
transmembrane 9 superfamily protein member 5
chr4_+_16710001 0.19 ENSDART00000035899
pkp2
plakophilin 2
chr15_+_34699585 0.19 ENSDART00000017569
tnfb
tumor necrosis factor b (TNF superfamily, member 2)
chr2_-_17827983 0.19 ENSDART00000166518
ptprfb
protein tyrosine phosphatase, receptor type, f, b
chr8_+_53051701 0.19 ENSDART00000131514
nadka
NAD kinase a
chr17_+_2162916 0.19 ENSDART00000103775
pak6a
p21 protein (Cdc42/Rac)-activated kinase 6a
chr9_-_21231297 0.19 ENSDART00000162578
pla1a
phospholipase A1 member A
chr11_+_3254252 0.18 ENSDART00000123568
pmela
premelanosome protein a
chr18_-_39702327 0.18 ENSDART00000149158
dmxl2
Dmx-like 2
chr23_+_43489182 0.18 ENSDART00000162062
znf341
zinc finger protein 341
chr19_+_636886 0.18 ENSDART00000149192
tert
telomerase reverse transcriptase
chr25_+_34013093 0.18 ENSDART00000011967
anxa2a
annexin A2a
chr21_+_30950097 0.18 ENSDART00000187572
rhogb
ras homolog family member Gb
chr1_-_20271138 0.18 ENSDART00000185931
ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr8_+_49975160 0.18 ENSDART00000156403
ENSDART00000080135
gfpt1
glutamine--fructose-6-phosphate transaminase 1
chr12_-_49168398 0.18 ENSDART00000186608
FO704624.1

chr6_+_42818963 0.18 ENSDART00000184833
sema3fa
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr16_+_11029762 0.18 ENSDART00000091183
erfl3
Ets2 repressor factor like 3
chr17_+_53435279 0.18 ENSDART00000126630
cx52.9
connexin 52.9
chr7_+_25053331 0.18 ENSDART00000173998
si:dkey-23i12.7
si:dkey-23i12.7
chr11_-_24191928 0.18 ENSDART00000136827
sox12
SRY (sex determining region Y)-box 12
chr6_+_42819337 0.17 ENSDART00000046498
sema3fa
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr5_-_26093945 0.17 ENSDART00000010199
ENSDART00000145096
fam219ab
family with sequence similarity 219, member Ab
chr1_-_8653385 0.17 ENSDART00000193041
actb1
actin, beta 1
chr9_-_30274412 0.17 ENSDART00000089526
otc
ornithine carbamoyltransferase
chr17_+_12698532 0.17 ENSDART00000064509
ENSDART00000136830
stmn4l
stathmin-like 4, like
chr21_-_7882905 0.17 ENSDART00000056561
s100z
S100 calcium binding protein Z
chr5_+_46293850 0.17 ENSDART00000140636
si:ch211-130m23.2
si:ch211-130m23.2
chr18_+_402048 0.17 ENSDART00000166345
gpib
glucose-6-phosphate isomerase b
chr16_+_68069 0.16 ENSDART00000185385
ENSDART00000159652
sox4b
SRY (sex determining region Y)-box 4b
chr4_+_63484571 0.16 ENSDART00000169518
ENSDART00000168681
si:dkey-11d20.1
si:dkey-11d20.1
chr13_-_39947335 0.16 ENSDART00000056996
sfrp5
secreted frizzled-related protein 5
chr3_-_61185746 0.16 ENSDART00000028219
pvalb4
parvalbumin 4
chr24_+_2519761 0.16 ENSDART00000106619
nrn1a
neuritin 1a
chr10_+_15777064 0.16 ENSDART00000114483
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr4_-_58846245 0.16 ENSDART00000170777
si:dkey-28i19.1
si:dkey-28i19.1
chr13_+_31144305 0.15 ENSDART00000189602
CR931802.4

chr22_+_38581012 0.15 ENSDART00000169239
BX088728.1

chr20_+_13969414 0.15 ENSDART00000049864
rd3
retinal degeneration 3
chr14_-_36863432 0.15 ENSDART00000158052
rnf130
ring finger protein 130
chr22_-_6651382 0.15 ENSDART00000124308
si:ch211-209l18.4
si:ch211-209l18.4
chr3_+_23737795 0.15 ENSDART00000182247
hoxb3a
homeobox B3a
chr18_+_41495841 0.15 ENSDART00000098671
si:ch211-203b8.6
si:ch211-203b8.6
chr11_+_37251825 0.15 ENSDART00000169804
il17rc
interleukin 17 receptor C
chr5_-_68022631 0.15 ENSDART00000143199
wasf3a
WAS protein family, member 3a
chr11_-_236766 0.15 ENSDART00000163978
dusp7
dual specificity phosphatase 7
chr21_+_11415224 0.15 ENSDART00000049036
zgc:92275
zgc:92275
chr24_+_3963684 0.15 ENSDART00000182959
ENSDART00000185926
ENSDART00000167043
ENSDART00000033394
pfkpa
phosphofructokinase, platelet a
chr3_-_38918697 0.15 ENSDART00000145630
si:dkey-106c17.2
si:dkey-106c17.2
chr3_+_23692462 0.15 ENSDART00000145934
hoxb7a
homeobox B7a
chr11_-_236984 0.15 ENSDART00000170778
dusp7
dual specificity phosphatase 7
chr17_+_53311618 0.15 ENSDART00000166517
asb2b
ankyrin repeat and SOCS box containing 2b
chr5_-_72136548 0.15 ENSDART00000007827
spra
sepiapterin reductase a
chr16_-_12173399 0.14 ENSDART00000142574
clstn3
calsyntenin 3
chr1_-_22861348 0.14 ENSDART00000139412
SMIM18
si:dkey-92j12.6
chr24_-_31439841 0.14 ENSDART00000169952
cngb3.2
cyclic nucleotide gated channel beta 3, tandem duplicate 2
chr3_-_30685401 0.14 ENSDART00000151097
si:ch211-51c14.1
si:ch211-51c14.1
chr2_-_7431590 0.14 ENSDART00000185699
asip2b
agouti signaling protein, nonagouti homolog (mouse) 2b
chr10_+_252425 0.14 ENSDART00000059478
lrrc32
leucine rich repeat containing 32
chr12_+_13282797 0.14 ENSDART00000137757
ENSDART00000152397
irf9
interferon regulatory factor 9
chr7_-_69636502 0.14 ENSDART00000126739
tspan5a
tetraspanin 5a
chr3_+_40315410 0.14 ENSDART00000083241
ENSDART00000132827
slc29a4
solute carrier family 29 (equilibrative nucleoside transporter), member 4
chr11_+_7324704 0.13 ENSDART00000031937
diras1a
DIRAS family, GTP-binding RAS-like 1a
chr22_-_18746508 0.13 ENSDART00000003929
midn
midnolin
chr3_+_62217479 0.13 ENSDART00000175012
BX470259.4

chr2_-_37874647 0.13 ENSDART00000039386
zgc:66427
zgc:66427
chr1_+_47459723 0.13 ENSDART00000015046
fstl1a
follistatin-like 1a
chr1_-_59176949 0.13 ENSDART00000128742
CABZ01118678.1

chr5_+_43870389 0.13 ENSDART00000141002
zgc:112966
zgc:112966
chr8_+_6576940 0.13 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr11_+_329687 0.13 ENSDART00000172882
cyp27b1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr15_-_22074315 0.13 ENSDART00000149830
drd2a
dopamine receptor D2a
chr5_-_37252111 0.13 ENSDART00000185110
lrch2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr13_+_51853716 0.13 ENSDART00000175341
ENSDART00000187855
LT631684.1

chr25_+_37348730 0.13 ENSDART00000156639
pamr1
peptidase domain containing associated with muscle regeneration 1
chr2_+_30147504 0.13 ENSDART00000190947
kcnb2
potassium voltage-gated channel, Shab-related subfamily, member 2
chr2_-_155270 0.13 ENSDART00000131177
adcy1b
adenylate cyclase 1b
chr1_+_44941031 0.13 ENSDART00000141145
si:dkey-9i23.16
si:dkey-9i23.16
chr1_+_57187794 0.13 ENSDART00000152485
si:dkey-27j5.9
si:dkey-27j5.9
chr14_+_918287 0.12 ENSDART00000167066
CU462913.1

chr3_-_46818001 0.12 ENSDART00000166505
elavl3
ELAV like neuron-specific RNA binding protein 3
chr3_+_60007703 0.12 ENSDART00000157351
ENSDART00000153928
ENSDART00000155876
si:ch211-110e21.3
si:ch211-110e21.3
chr15_+_31526225 0.12 ENSDART00000154456
wdr95
WD40 repeat domain 95
chr15_-_1687204 0.12 ENSDART00000155579
ENSDART00000181382
sptssb
serine palmitoyltransferase, small subunit B
chr19_-_10196370 0.12 ENSDART00000091707
dbpa
D site albumin promoter binding protein a

Network of associatons between targets according to the STRING database.

First level regulatory network of egr2a+egr2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0019695 choline metabolic process(GO:0019695)
0.2 0.7 GO:0002369 T cell cytokine production(GO:0002369)
0.2 0.5 GO:0032060 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.2 0.5 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341) intermediate mesoderm development(GO:0048389)
0.1 0.9 GO:0033986 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.1 0.4 GO:0097435 fibril organization(GO:0097435)
0.1 0.4 GO:0048785 hatching gland development(GO:0048785)
0.1 0.3 GO:0010312 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.1 0.3 GO:0060471 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.1 0.5 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 0.4 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.1 0.4 GO:0061072 iris morphogenesis(GO:0061072)
0.1 0.5 GO:0021571 rhombomere 5 development(GO:0021571) rhombomere 6 development(GO:0021572)
0.1 0.3 GO:0097037 heme export(GO:0097037)
0.1 0.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.2 GO:1901546 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.1 0.2 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.1 0.2 GO:0021856 pallium development(GO:0021543) cerebral cortex cell migration(GO:0021795) cerebral cortex tangential migration(GO:0021800) cerebral cortex tangential migration using cell-axon interactions(GO:0021824) substrate-dependent cerebral cortex tangential migration(GO:0021825) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) cerebral cortex development(GO:0021987)
0.1 0.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1 0.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.2 GO:1903589 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.0 0.1 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.0 0.4 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.4 GO:0021703 locus ceruleus development(GO:0021703)
0.0 0.4 GO:0071632 optomotor response(GO:0071632)
0.0 0.4 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.2 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.2 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.0 0.4 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.2 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.0 0.4 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.2 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.2 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.4 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.5 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.2 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0061551 trigeminal ganglion development(GO:0061551)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.9 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.5 GO:0014823 response to activity(GO:0014823)
0.0 0.2 GO:0006868 glutamine transport(GO:0006868)
0.0 0.4 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.2 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.3 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0097272 ammonia homeostasis(GO:0097272)
0.0 0.3 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.2 GO:1902042 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.5 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0001774 microglial cell activation(GO:0001774)
0.0 0.1 GO:0042559 tetrahydrobiopterin biosynthetic process(GO:0006729) pteridine-containing compound biosynthetic process(GO:0042559) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.0 0.5 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.0 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.1 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.0 0.1 GO:0030825 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.3 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.4 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.0 GO:0045023 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 0.7 GO:0045095 keratin filament(GO:0045095)
0.1 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0043291 RAVE complex(GO:0043291)
0.0 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.4 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0014704 intercalated disc(GO:0014704)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.5 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0033010 paranodal junction(GO:0033010)
0.0 0.1 GO:0043194 axon initial segment(GO:0043194)
0.0 0.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0070062 extracellular exosome(GO:0070062)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.4 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.1 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.2 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.1 1.0 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.2 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.6 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.2 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.2 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.3 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.7 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.3 GO:0016248 ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
0.0 0.1 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.7 ST GAQ PATHWAY G alpha q Pathway
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.1 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis