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PRJNA195909:zebrafish embryo and larva development

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Results for en1a

Z-value: 0.35

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Transcription factors associated with en1a

Gene Symbol Gene ID Gene Info
en1a
ENSDARG00000014321 engrailed homeobox 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
en1adr11_v1_chr9_-_785444_7854440.511.7e-01Click!

Activity profile of en1a motif

Sorted Z-values of en1a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_44713135 0.70 ENSDART00000170721
si:dkey-56m19.5
si:dkey-56m19.5
chr13_-_9525527 0.56 ENSDART00000190618
CR848040.5

chr5_-_65021736 0.55 ENSDART00000162368
ENSDART00000161876
anxa1c
annexin A1c
chr2_-_16562505 0.49 ENSDART00000156406
atp1b3a
ATPase Na+/K+ transporting subunit beta 3a
chr19_-_3240605 0.47 ENSDART00000105168
si:ch211-133n4.4
si:ch211-133n4.4
chr7_+_29954709 0.47 ENSDART00000173904
tpma
alpha-tropomyosin
chr3_+_26345732 0.46 ENSDART00000128613
rps15a
ribosomal protein S15a
chr3_+_28939759 0.42 ENSDART00000141904
lgals1l1
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
chr7_+_29955368 0.40 ENSDART00000173686
tpma
alpha-tropomyosin
chr8_+_13503377 0.35 ENSDART00000034740
ENSDART00000167187
fut9d
fucosyltransferase 9d
chr23_+_36653376 0.33 ENSDART00000053189
gpr182
G protein-coupled receptor 182
chr5_-_30615901 0.32 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr7_-_34265481 0.32 ENSDART00000173596
si:ch211-98n17.5
si:ch211-98n17.5
chr14_-_21123551 0.31 ENSDART00000171679
ENSDART00000165882
si:dkey-74k8.4
si:dkey-74k8.4
chr8_-_50147948 0.30 ENSDART00000149010
hp
haptoglobin
chr9_+_21277846 0.30 ENSDART00000139620
ENSDART00000110996
ENSDART00000111899
lats2
large tumor suppressor kinase 2
chr7_-_69636502 0.30 ENSDART00000126739
tspan5a
tetraspanin 5a
chr17_-_44249720 0.30 ENSDART00000156648
otx2b
orthodenticle homeobox 2b
chr2_+_26498446 0.30 ENSDART00000078412
rps8a
ribosomal protein S8a
chr5_-_8164439 0.29 ENSDART00000189912
slc1a3a
solute carrier family 1 (glial high affinity glutamate transporter), member 3a
chr1_-_59287410 0.29 ENSDART00000158011
ENSDART00000170580
col5a3b
collagen, type V, alpha 3b
chr11_+_3989403 0.29 ENSDART00000082379
spcs1
signal peptidase complex subunit 1
chr2_-_24554416 0.29 ENSDART00000052061
cnn2
calponin 2
chr19_-_18626515 0.28 ENSDART00000160624
rps18
ribosomal protein S18
chr15_-_19771981 0.28 ENSDART00000175502
ENSDART00000159475
picalmb
phosphatidylinositol binding clathrin assembly protein b
chr7_+_31879986 0.27 ENSDART00000138491
mybpc3
myosin binding protein C, cardiac
chr24_-_32408404 0.27 ENSDART00000144157
si:ch211-56a11.2
si:ch211-56a11.2
chr6_+_47424266 0.27 ENSDART00000171087
si:ch211-286o17.1
si:ch211-286o17.1
chr5_+_69716458 0.27 ENSDART00000159594
mthfd2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr23_+_42396934 0.27 ENSDART00000169821
cyp2aa8
cytochrome P450, family 2, subfamily AA, polypeptide 8
chr15_-_20233105 0.26 ENSDART00000123910
ppp1r14ab
protein phosphatase 1, regulatory (inhibitor) subunit 14Ab
chr20_+_16750177 0.26 ENSDART00000185357
calm1b
calmodulin 1b
chr5_-_44843738 0.25 ENSDART00000003926
fbp1a
fructose-1,6-bisphosphatase 1a
chr8_+_25616946 0.25 ENSDART00000133983
slc38a5a
solute carrier family 38, member 5a
chr15_+_23799461 0.25 ENSDART00000154885
si:ch211-167j9.4
si:ch211-167j9.4
chr20_+_34845672 0.25 ENSDART00000128895
emilin1a
elastin microfibril interfacer 1a
chr9_-_33121535 0.24 ENSDART00000166371
ENSDART00000138052
zgc:172014
zgc:172014
chr6_-_13783604 0.24 ENSDART00000149536
ENSDART00000041269
ENSDART00000150102
cryba2a
crystallin, beta A2a
chr20_+_539852 0.24 ENSDART00000185994
dse
dermatan sulfate epimerase
chr4_-_52165969 0.23 ENSDART00000171130
si:dkeyp-44b5.4
si:dkeyp-44b5.4
chr13_-_15700060 0.23 ENSDART00000170689
ENSDART00000010986
ENSDART00000101741
ENSDART00000139124
ckba
creatine kinase, brain a
chr23_+_42819221 0.23 ENSDART00000180495
myl9a
myosin, light chain 9a, regulatory
chr20_-_20312789 0.23 ENSDART00000114779
si:ch211-212g7.6
si:ch211-212g7.6
chr3_+_23768898 0.22 ENSDART00000110682
hoxb1a
homeobox B1a
chr1_-_13271569 0.22 ENSDART00000127838
pcdh18a
protocadherin 18a
chr10_+_33982010 0.22 ENSDART00000180431
fryb
furry homolog b (Drosophila)
chr11_+_23569869 0.22 ENSDART00000163418
si:ch73-21d24.1
si:ch73-21d24.1
chr16_+_54780544 0.22 ENSDART00000126646
si:zfos-1192g2.3
si:zfos-1192g2.3
chr14_-_9277152 0.22 ENSDART00000189048
asb12b
ankyrin repeat and SOCS box-containing 12b
chr1_+_34295925 0.21 ENSDART00000075584
kctd12.2
potassium channel tetramerisation domain containing 12.2
chr5_-_55625247 0.21 ENSDART00000133156
hnrpkl
heterogeneous nuclear ribonucleoprotein K, like
chr3_+_14543953 0.21 ENSDART00000161710
epor
erythropoietin receptor
chr8_+_26565512 0.21 ENSDART00000140980
sema3bl
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl
chr6_-_39764995 0.20 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr19_-_31402429 0.20 ENSDART00000137292
tmem106bb
transmembrane protein 106Bb
chr6_+_46320693 0.19 ENSDART00000128621
ENSDART00000155917
si:dkeyp-67f1.2
si:dkeyp-67f1.2
chr19_+_43780970 0.19 ENSDART00000063870
rpl11
ribosomal protein L11
chr12_+_34119439 0.19 ENSDART00000032821
cyth1b
cytohesin 1b
chr24_+_9372292 0.19 ENSDART00000082422
ENSDART00000191127
ENSDART00000180510
si:ch211-285f17.1
si:ch211-285f17.1
chr15_-_2632891 0.19 ENSDART00000081840
cldnj
claudin j
chr17_-_6349044 0.19 ENSDART00000081707
oct2
organic cation transporter 2
chr6_-_40195510 0.18 ENSDART00000156156
col7a1
collagen, type VII, alpha 1
chr3_-_6767440 0.18 ENSDART00000156174
mast1b
microtubule associated serine/threonine kinase 1b
chr23_+_26946744 0.18 ENSDART00000115141
cacnb3b
calcium channel, voltage-dependent, beta 3b
chr1_-_11913170 0.18 ENSDART00000165543
grk4
G protein-coupled receptor kinase 4
chr11_-_44876005 0.18 ENSDART00000192006
opn6a
opsin 6, group member a
chr18_-_41375120 0.18 ENSDART00000098673
ptx3a
pentraxin 3, long a
chr11_+_42633376 0.17 ENSDART00000076711
appl1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr19_+_25476228 0.17 ENSDART00000112808
col28a1a
collagen, type XXVIII, alpha 1a
chr2_+_22495274 0.17 ENSDART00000167915
lrrc8da
leucine rich repeat containing 8 VRAC subunit Da
chr10_+_38512270 0.17 ENSDART00000109752
serpinh1a
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a
chr15_+_37197494 0.17 ENSDART00000166203
aplp1
amyloid beta (A4) precursor-like protein 1
chr2_-_1514001 0.17 ENSDART00000057736
c8b
complement component 8, beta polypeptide
chr13_-_29424454 0.17 ENSDART00000026765
slc18a3a
solute carrier family 18 (vesicular acetylcholine transporter), member 3a
chr16_+_5196226 0.16 ENSDART00000189704
soga3a
SOGA family member 3a
chr3_+_12784460 0.16 ENSDART00000168382
cyp2k8
cytochrome P450, family 2, subfamily K, polypeptide 8
chr4_-_17805128 0.16 ENSDART00000128988
spi2
Spi-2 proto-oncogene
chr3_-_41795917 0.16 ENSDART00000182662
grifin
galectin-related inter-fiber protein
chr6_+_21684296 0.16 ENSDART00000057223
rhebl1
Ras homolog, mTORC1 binding like 1
chr5_-_64203101 0.16 ENSDART00000029364
ak5l
adenylate kinase 5, like
chr16_-_45080812 0.15 ENSDART00000157377
si:rp71-77l1.2
si:rp71-77l1.2
chr1_+_54865552 0.15 ENSDART00000145381
si:ch211-196h16.5
si:ch211-196h16.5
chr15_-_19772372 0.15 ENSDART00000152729
picalmb
phosphatidylinositol binding clathrin assembly protein b
chr7_+_31879649 0.15 ENSDART00000099789
mybpc3
myosin binding protein C, cardiac
chr6_+_28124393 0.15 ENSDART00000089195
gpr17
G protein-coupled receptor 17
chr13_+_27314795 0.15 ENSDART00000128726
eef1a1a
eukaryotic translation elongation factor 1 alpha 1a
chr21_-_40676224 0.15 ENSDART00000162623
arxb
aristaless related homeobox b
chr23_+_28770225 0.14 ENSDART00000132179
ENSDART00000142273
masp2
mannan-binding lectin serine peptidase 2
chr25_-_31953516 0.14 ENSDART00000110180
duox2
dual oxidase 2
chr2_+_22531185 0.14 ENSDART00000171959
hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr8_-_25338709 0.14 ENSDART00000131616
atp5pb
ATP synthase peripheral stalk-membrane subunit b
chr23_+_1730663 0.14 ENSDART00000149545
tgm1
transglutaminase 1, K polypeptide
chr5_+_52067723 0.14 ENSDART00000166902
setbp1
SET binding protein 1
chr3_-_32934359 0.14 ENSDART00000124160
aoc2
amine oxidase, copper containing 2
chr20_+_10723292 0.14 ENSDART00000152805
si:ch211-182e10.4
si:ch211-182e10.4
chr5_-_28038623 0.13 ENSDART00000160013
zgc:113436
zgc:113436
chr19_-_3381422 0.13 ENSDART00000105146
edn1
endothelin 1
chr19_-_10810006 0.13 ENSDART00000151157
si:dkey-3n22.9
si:dkey-3n22.9
chr15_-_6976851 0.13 ENSDART00000158474
ENSDART00000168943
ENSDART00000169944
si:ch73-311h14.2
si:ch73-311h14.2
chr15_+_14854666 0.13 ENSDART00000163066
diabloa
diablo, IAP-binding mitochondrial protein a
chr11_+_30513656 0.13 ENSDART00000008594
tmem178
transmembrane protein 178
chr2_+_32780138 0.13 ENSDART00000082250
zgc:136930
zgc:136930
chr10_-_16062565 0.12 ENSDART00000188728
si:dkey-184a18.5
si:dkey-184a18.5
chr22_+_38159823 0.12 ENSDART00000104527
tm4sf18
transmembrane 4 L six family member 18
chr15_-_14210382 0.12 ENSDART00000179599
CR925813.1

chr16_+_52748263 0.12 ENSDART00000032275
atp6v1c1a
ATPase H+ transporting V1 subunit C1a
chr7_+_32722227 0.12 ENSDART00000126565
si:ch211-150g13.3
si:ch211-150g13.3
chr24_+_18299175 0.12 ENSDART00000140994
tpk1
thiamin pyrophosphokinase 1
chr8_-_38403018 0.12 ENSDART00000134100
sorbs3
sorbin and SH3 domain containing 3
chr7_-_35409027 0.12 ENSDART00000128334
lpcat2
lysophosphatidylcholine acyltransferase 2
chr12_+_17754859 0.12 ENSDART00000112119
bhlha15
basic helix-loop-helix family, member a15
chr22_+_17120473 0.12 ENSDART00000170076
ENSDART00000090217
frem1b
Fras1 related extracellular matrix 1b
chr3_+_5504990 0.12 ENSDART00000143626
si:ch73-264i18.2
si:ch73-264i18.2
chr16_+_41570653 0.12 ENSDART00000102665
aste1a
asteroid homolog 1a
chr21_+_15824182 0.12 ENSDART00000065779
gnrh2
gonadotropin-releasing hormone 2
chr9_-_17417628 0.11 ENSDART00000060425
ENSDART00000141997
ftr53
finTRIM family, member 53
chr4_-_28958601 0.11 ENSDART00000111294
zgc:174315
zgc:174315
chr4_+_57099307 0.11 ENSDART00000131654
si:ch211-238e22.2
si:ch211-238e22.2
chr19_+_7495791 0.11 ENSDART00000010862
mrpl24
mitochondrial ribosomal protein L24
chr17_+_42274825 0.11 ENSDART00000020156
pax1a
paired box 1a
chr2_-_3045861 0.11 ENSDART00000105818
ENSDART00000187575
guk1a
guanylate kinase 1a
chr5_-_64213253 0.11 ENSDART00000171711
gpsm1a
G protein signaling modulator 1a
chr4_+_14660769 0.11 ENSDART00000168152
ENSDART00000013990
ENSDART00000079987
abcc9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr7_-_10560964 0.11 ENSDART00000172761
ENSDART00000170476
mthfs
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr4_+_912563 0.11 ENSDART00000103631
ripply2
ripply transcriptional repressor 2
chr4_+_68476490 0.11 ENSDART00000168543
si:dkey-237g15.2
si:dkey-237g15.2
chr19_+_14921000 0.10 ENSDART00000144052
oprd1a
opioid receptor, delta 1a
chr1_-_38171648 0.10 ENSDART00000137451
ENSDART00000047159
hmgb2a
high mobility group box 2a
chr9_+_14152211 0.10 ENSDART00000148055
si:ch211-67e16.11
si:ch211-67e16.11
chr6_-_55958705 0.10 ENSDART00000155963
eya2
EYA transcriptional coactivator and phosphatase 2
chr10_+_43189325 0.10 ENSDART00000185584
vcanb
versican b
chr10_+_38708099 0.10 ENSDART00000172306
tmprss2
transmembrane protease, serine 2
chr7_-_6470431 0.10 ENSDART00000081359
zgc:110425
zgc:110425
chr21_-_42055872 0.09 ENSDART00000144767
gabra1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr14_+_38845674 0.09 ENSDART00000129958
hnrnpa0b
heterogeneous nuclear ribonucleoprotein A0b
chr5_-_46152740 0.09 ENSDART00000123144
f2rl2
coagulation factor II (thrombin) receptor-like 2
chr5_+_22459087 0.09 ENSDART00000134781
BX546499.1

chr19_+_1370504 0.09 ENSDART00000158946
dgat1a
diacylglycerol O-acyltransferase 1a
chr11_+_24716837 0.09 ENSDART00000145217
zgc:153953
zgc:153953
chr7_+_49664174 0.09 ENSDART00000137059
ENSDART00000131210
rassf7b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr1_-_38170997 0.09 ENSDART00000142811
hmgb2a
high mobility group box 2a
chr23_-_31512496 0.09 ENSDART00000158755
ENSDART00000143425
eya4
EYA transcriptional coactivator and phosphatase 4
chr25_+_19095231 0.09 ENSDART00000154066
isg20
interferon stimulated exonuclease gene
chr21_+_25198637 0.09 ENSDART00000164972
si:dkey-183i3.6
si:dkey-183i3.6
chr15_+_15779184 0.09 ENSDART00000156902
si:ch211-33e4.2
si:ch211-33e4.2
chr7_+_3489195 0.09 ENSDART00000183876
si:ch211-285c6.3
si:ch211-285c6.3
chr3_+_62205858 0.09 ENSDART00000126807
zgc:173575
zgc:173575
chr2_-_985417 0.08 ENSDART00000140540
si:ch211-241e1.3
si:ch211-241e1.3
chr20_+_43942278 0.08 ENSDART00000100571
clic5b
chloride intracellular channel 5b
chr13_+_15215633 0.08 ENSDART00000133041
pank2
pantothenate kinase 2
chr5_-_38197080 0.08 ENSDART00000140708
si:ch211-284e13.9
si:ch211-284e13.9
chr13_+_22476742 0.08 ENSDART00000078759
ENSDART00000130101
ENSDART00000137220
ENSDART00000133065
ENSDART00000147348
ldb3a
LIM domain binding 3a
chr8_+_17167876 0.08 ENSDART00000134665
cenph
centromere protein H
chr2_+_45441563 0.08 ENSDART00000151882
si:ch211-66k16.27
si:ch211-66k16.27
chr2_-_58257624 0.08 ENSDART00000098940
foxl2b
forkhead box L2b
chr9_+_38420028 0.08 ENSDART00000135748
cyp27a1.2
cytochrome P450, family 27, subfamily A, polypeptide 1, gene 2
chr19_-_29832876 0.08 ENSDART00000005119
eif3i
eukaryotic translation initiation factor 3, subunit I
chr3_+_13332870 0.08 ENSDART00000113878
CU138547.1

chr15_-_14552101 0.08 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr25_+_7504314 0.08 ENSDART00000163231
ifitm5
interferon induced transmembrane protein 5
chr5_+_21225017 0.07 ENSDART00000141573
si:dkey-13n15.11
si:dkey-13n15.11
chr10_+_9281991 0.07 ENSDART00000139156
slc37a4b
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr14_-_38872536 0.07 ENSDART00000184315
ENSDART00000127479
gsr
glutathione reductase
chr6_+_39184236 0.07 ENSDART00000156187
tac3b
tachykinin 3b
chr4_-_62714083 0.07 ENSDART00000188299
si:dkey-28k24.2
si:dkey-28k24.2
chr2_-_57991638 0.07 ENSDART00000183937
si:dkeyp-68b7.12
si:dkeyp-68b7.12
chr7_+_12931396 0.07 ENSDART00000184664
fth1a
ferritin, heavy polypeptide 1a
chr13_-_1130096 0.07 ENSDART00000010261
pno1
partner of NOB1 homolog
chr8_-_50888806 0.07 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr18_-_21859019 0.07 ENSDART00000100885
nrn1la
neuritin 1-like a
chr3_-_3939785 0.07 ENSDART00000049593
unm_sa1506
un-named sa1506
chr17_-_45734231 0.07 ENSDART00000074873
arf6b
ADP-ribosylation factor 6b
chr4_-_75707991 0.07 ENSDART00000166358
ENSDART00000160021
si:dkey-165o8.2
si:dkey-165o8.2
chr21_-_25618175 0.07 ENSDART00000133512
fosl1b
FOS-like antigen 1b
chr2_+_26656283 0.07 ENSDART00000133202
ENSDART00000099208
asph
aspartate beta-hydroxylase
chr8_-_13210959 0.07 ENSDART00000142224
si:ch73-61d6.3
si:ch73-61d6.3
chr2_-_51794472 0.07 ENSDART00000186652
BX908782.3

chr22_-_20733822 0.07 ENSDART00000133780
si:dkey-3k20.1
si:dkey-3k20.1
chr4_-_73136420 0.07 ENSDART00000160907
si:ch73-170d6.3
si:ch73-170d6.3
chr6_+_18321627 0.07 ENSDART00000183107
ENSDART00000189715
card14
caspase recruitment domain family, member 14
chr9_-_9998087 0.06 ENSDART00000124423
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr9_+_38408991 0.06 ENSDART00000045588
cyp27a7
cytochrome P450, family 27, subfamily A, polypeptide 7
chr23_-_26652273 0.06 ENSDART00000112124
ENSDART00000111029
hspg2
heparan sulfate proteoglycan 2
chr4_+_66853199 0.06 ENSDART00000170223
si:dkey-29m1.2
si:dkey-29m1.2
chr16_+_24626448 0.06 ENSDART00000153591
si:dkey-56f14.7
si:dkey-56f14.7
chr14_+_16813816 0.06 ENSDART00000161201
limch1b
LIM and calponin homology domains 1b
chr19_-_10648523 0.06 ENSDART00000059358
tekt2
tektin 2 (testicular)
chr19_+_9091673 0.06 ENSDART00000052898
si:ch211-81a5.5
si:ch211-81a5.5
chr1_+_49682312 0.06 ENSDART00000136747
si:ch211-149l1.2
si:ch211-149l1.2
chr4_-_76154252 0.06 ENSDART00000161269
BX957252.1

chr5_-_16983336 0.06 ENSDART00000038740
galnt9
polypeptide N-acetylgalactosaminyltransferase 9
chr10_+_40762200 0.06 ENSDART00000161000
ENSDART00000136185
taar19g
trace amine associated receptor 19g
chr11_-_43948885 0.06 ENSDART00000164522
CABZ01074203.1

chr8_+_17168114 0.06 ENSDART00000183901
cenph
centromere protein H
chr25_-_3469576 0.06 ENSDART00000186738
hbp1
HMG-box transcription factor 1
chr16_+_26017360 0.06 ENSDART00000149466
prss59.2
protease, serine, 59, tandem duplicate 2
chr17_-_465285 0.06 ENSDART00000168718
chrm5a
cholinergic receptor, muscarinic 5a
chr1_+_12009673 0.06 ENSDART00000080100
slc24a2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr24_-_1356668 0.06 ENSDART00000188935
nrp1a
neuropilin 1a
chr25_+_6186823 0.05 ENSDART00000153526
oaz2a
ornithine decarboxylase antizyme 2a

Network of associatons between targets according to the STRING database.

First level regulatory network of en1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0042088 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.3 GO:0046351 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.1 0.4 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 0.2 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.1 0.2 GO:0002792 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.1 0.3 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.2 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0044108 calcitriol biosynthetic process from calciol(GO:0036378) vitamin D biosynthetic process(GO:0042368) cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
0.0 0.2 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.2 GO:0044068 modification by symbiont of host morphology or physiology(GO:0044003) modulation by symbiont of host cellular process(GO:0044068)
0.0 0.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.1 GO:0009229 thiamine diphosphate biosynthetic process(GO:0009229)
0.0 0.2 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.2 GO:0021661 rhombomere 4 development(GO:0021570) rhombomere 4 morphogenesis(GO:0021661)
0.0 0.1 GO:0060584 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.5 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.3 GO:0046620 secondary heart field specification(GO:0003139) regulation of organ growth(GO:0046620)
0.0 0.4 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.4 GO:0036065 fucosylation(GO:0036065)
0.0 0.2 GO:1901099 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.2 GO:0061621 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.2 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.3 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.4 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.2 GO:0032418 lysosome localization(GO:0032418)
0.0 0.1 GO:0042264 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.0 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.0 1.1 GO:0061515 myeloid cell development(GO:0061515)
0.0 0.0 GO:0070227 lymphocyte apoptotic process(GO:0070227)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.4 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0016460 myosin II complex(GO:0016460)
0.0 0.3 GO:0015935 small ribosomal subunit(GO:0015935)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.3 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.2 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0031073 vitamin D3 25-hydroxylase activity(GO:0030343) cholesterol 26-hydroxylase activity(GO:0031073)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.4 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0004788 thiamine diphosphokinase activity(GO:0004788) thiamine binding(GO:0030975)
0.0 0.1 GO:0005183 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0038046 enkephalin receptor activity(GO:0038046)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 0.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.3 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.0 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade