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PRJNA195909:zebrafish embryo and larva development

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Results for esr1+esr2a+esr2b

Z-value: 2.50

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Transcription factors associated with esr1+esr2a+esr2b

Gene Symbol Gene ID Gene Info
esr1
ENSDARG00000004111 estrogen receptor 1
esr2a
ENSDARG00000016454 estrogen receptor 2a
esr2b
ENSDARG00000034181 estrogen receptor 2b
esr1
ENSDARG00000112357 estrogen receptor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
esr1dr11_v1_chr20_-_26383368_263833750.891.4e-03Click!
esr2bdr11_v1_chr13_+_37022601_370226320.835.5e-03Click!
esr2adr11_v1_chr20_+_21583639_21583639-0.722.8e-02Click!

Activity profile of esr1+esr2a+esr2b motif

Sorted Z-values of esr1+esr2a+esr2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_44027391 9.55 ENSDART00000145404
crybb1
crystallin, beta B1
chr12_-_43685802 5.06 ENSDART00000170723
zgc:112964
zgc:112964
chr9_-_22310919 4.60 ENSDART00000108719
crygm2d10
crystallin, gamma M2d10
chr5_-_71722257 4.07 ENSDART00000013404
ak1
adenylate kinase 1
chr19_-_5332784 3.82 ENSDART00000010373
krt1-19d
keratin, type 1, gene 19d
chr10_+_9561066 3.66 ENSDART00000136281
si:ch211-243g18.2
si:ch211-243g18.2
chr7_+_20017211 3.64 ENSDART00000100808
bcl6b
B-cell CLL/lymphoma 6, member B
chr23_+_44741500 3.53 ENSDART00000166421
atp1b2a
ATPase Na+/K+ transporting subunit beta 2a
chr9_-_22240052 3.44 ENSDART00000111109
crygm2d9
crystallin, gamma M2d9
chr10_-_29900546 3.44 ENSDART00000147441
lim2.1
lens intrinsic membrane protein 2.1
chr12_-_4683325 3.42 ENSDART00000152771
si:ch211-255p10.3
si:ch211-255p10.3
chr9_-_22147567 3.40 ENSDART00000110941
crygm2d14
crystallin, gamma M2d14
chr9_-_22272181 3.36 ENSDART00000113174
crygm2d7
crystallin, gamma M2d7
chr11_+_30729745 3.33 ENSDART00000103270
slc22a7a
solute carrier family 22 (organic anion transporter), member 7a
chr9_-_22188117 3.31 ENSDART00000132890
crygm2d17
crystallin, gamma M2d17
chr12_-_30846055 3.18 ENSDART00000075983
crygmxl2
crystallin, gamma MX, like 2
chr6_+_55032439 3.12 ENSDART00000164232
ENSDART00000158845
ENSDART00000157584
ENSDART00000026359
ENSDART00000122794
ENSDART00000183742
mybphb
myosin binding protein Hb
chr9_+_54644626 3.05 ENSDART00000190609
egfl6
EGF-like-domain, multiple 6
chr9_-_22318511 3.04 ENSDART00000129295
crygm2d2
crystallin, gamma M2d2
chr20_-_40717900 3.00 ENSDART00000181663
cx43
connexin 43
chr9_-_22232902 2.99 ENSDART00000101845
crygm2d5
crystallin, gamma M2d5
chr5_-_55395964 2.97 ENSDART00000145791
prune2
prune homolog 2 (Drosophila)
chr15_+_19797918 2.93 ENSDART00000113314
si:ch211-229d2.5
si:ch211-229d2.5
chr7_+_40884012 2.91 ENSDART00000149395
shha
sonic hedgehog a
chr3_-_41795917 2.91 ENSDART00000182662
grifin
galectin-related inter-fiber protein
chr16_-_55028740 2.83 ENSDART00000156368
ENSDART00000161704
zgc:114181
zgc:114181
chr1_+_17676745 2.83 ENSDART00000030665
slc25a4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr16_+_29650698 2.81 ENSDART00000137153
tmod4
tropomodulin 4 (muscle)
chr13_-_37127970 2.78 ENSDART00000135510
syne2b
spectrin repeat containing, nuclear envelope 2b
chr18_+_62932 2.76 ENSDART00000052638
slc27a2a
solute carrier family 27 (fatty acid transporter), member 2a
chr1_-_59176949 2.76 ENSDART00000128742
CABZ01118678.1

chr11_-_6048490 2.75 ENSDART00000066164
plvapb
plasmalemma vesicle associated protein b
chr6_-_607063 2.75 ENSDART00000189900
lgals2b
lectin, galactoside-binding, soluble, 2b
chr15_+_32711663 2.75 ENSDART00000157854
ENSDART00000167515
postnb
periostin, osteoblast specific factor b
chr18_+_31016379 2.74 ENSDART00000172461
ENSDART00000163471
uraha
urate (5-hydroxyiso-) hydrolase a
chr22_-_15593824 2.69 ENSDART00000123125
tpm4a
tropomyosin 4a
chr19_+_19759577 2.64 ENSDART00000169480
hoxa5a
homeobox A5a
chr6_-_13783604 2.62 ENSDART00000149536
ENSDART00000041269
ENSDART00000150102
cryba2a
crystallin, beta A2a
chr2_-_5728843 2.60 ENSDART00000014020
sst2
somatostatin 2
chr9_-_7539297 2.59 ENSDART00000081550
ENSDART00000081553
desma
desmin a
chr6_+_15268685 2.53 ENSDART00000128090
ENSDART00000154417
ecrg4b
esophageal cancer related gene 4b
chr2_-_716426 2.48 ENSDART00000028159
foxf2a
forkhead box F2a
chr7_+_40228422 2.39 ENSDART00000052222
ptprn2
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr24_-_38374744 2.39 ENSDART00000007208
lrrc4bb
leucine rich repeat containing 4Bb
chr17_-_6738538 2.35 ENSDART00000157125
vsnl1b
visinin-like 1b
chr3_-_46811611 2.30 ENSDART00000134092
elavl3
ELAV like neuron-specific RNA binding protein 3
chr16_+_12022543 2.29 ENSDART00000012673
gnb3a
guanine nucleotide binding protein (G protein), beta polypeptide 3a
chr14_+_17376940 2.29 ENSDART00000054590
ENSDART00000010148
spon2b
spondin 2b, extracellular matrix protein
chr23_-_21471022 2.24 ENSDART00000104206
her4.2
hairy-related 4, tandem duplicate 2
chr11_+_7158723 2.19 ENSDART00000035560
tmem38a
transmembrane protein 38A
chr3_+_23737795 2.18 ENSDART00000182247
hoxb3a
homeobox B3a
chr25_+_23591990 2.15 ENSDART00000151938
ENSDART00000089199
cpt1ab
carnitine palmitoyltransferase 1Ab (liver)
chr2_-_24013260 2.15 ENSDART00000137065
col15a1b
collagen, type XV, alpha 1b
chr4_+_17280868 2.14 ENSDART00000145349
bcat1
branched chain amino-acid transaminase 1, cytosolic
chr7_-_51032128 2.13 ENSDART00000182781
ENSDART00000121574
col4a6
collagen, type IV, alpha 6
chr14_-_17072736 2.09 ENSDART00000106333
phox2bb
paired-like homeobox 2bb
chr5_-_46980651 2.08 ENSDART00000181022
ENSDART00000168038
edil3a
EGF-like repeats and discoidin I-like domains 3a
chr8_-_23758312 2.08 ENSDART00000132659
INAVA
si:ch211-163l21.4
chr20_+_54738210 2.07 ENSDART00000151399
pak7
p21 protein (Cdc42/Rac)-activated kinase 7
chr7_-_34265481 2.07 ENSDART00000173596
si:ch211-98n17.5
si:ch211-98n17.5
chr2_+_42191592 2.07 ENSDART00000144716
cavin4a
caveolae associated protein 4a
chr21_+_40106448 2.03 ENSDART00000100166
serpinf1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr9_-_22821901 2.01 ENSDART00000101711
neb
nebulin
chr4_-_16333944 2.00 ENSDART00000079523
epyc
epiphycan
chr6_-_11768198 1.99 ENSDART00000183463
march7
membrane-associated ring finger (C3HC4) 7
chr4_-_191736 1.99 ENSDART00000169187
ENSDART00000192054
ptpro
protein tyrosine phosphatase, receptor type, O
chr1_+_29096881 1.99 ENSDART00000075539
cryaa
crystallin, alpha A
chr23_-_26535875 1.97 ENSDART00000135988
si:dkey-205h13.2
si:dkey-205h13.2
chr1_-_40914752 1.97 ENSDART00000113087
hmx1
H6 family homeobox 1
chr17_-_12385308 1.95 ENSDART00000080927
snap25b
synaptosomal-associated protein, 25b
chr8_+_23213320 1.94 ENSDART00000032996
ENSDART00000137536
ppdpfa
pancreatic progenitor cell differentiation and proliferation factor a
chr6_+_12853655 1.93 ENSDART00000156341
fam117ba
family with sequence similarity 117, member Ba
chr20_-_22484621 1.93 ENSDART00000063601
gsx2
GS homeobox 2
chr13_+_15004398 1.93 ENSDART00000057810
emx1
empty spiracles homeobox 1
chr5_+_1278092 1.90 ENSDART00000147972
ENSDART00000159783
dnm1a
dynamin 1a
chr15_+_28096152 1.89 ENSDART00000100293
ENSDART00000140092
crybb1l3
crystallin, beta B1, like 3
chr13_-_31435137 1.87 ENSDART00000057441
rtn1a
reticulon 1a
chr5_+_20693724 1.87 ENSDART00000141368
si:ch211-240b21.2
si:ch211-240b21.2
chr5_-_65021736 1.85 ENSDART00000162368
ENSDART00000161876
anxa1c
annexin A1c
chr1_+_16144615 1.85 ENSDART00000054707
tusc3
tumor suppressor candidate 3
chr1_-_12278522 1.84 ENSDART00000142122
ENSDART00000003825
cplx2l
complexin 2, like
chr5_+_70155935 1.83 ENSDART00000165570
rgs3a
regulator of G protein signaling 3a
chr3_-_18575868 1.83 ENSDART00000122968
aqp8b
aquaporin 8b
chr24_-_39610585 1.82 ENSDART00000066506
cox6b1
cytochrome c oxidase subunit VIb polypeptide 1
chr16_+_23972126 1.82 ENSDART00000132742
ENSDART00000145330
apoc1
apolipoprotein C-I
chr13_-_9525527 1.82 ENSDART00000190618
CR848040.5

chr4_-_1360495 1.81 ENSDART00000164623
ptn
pleiotrophin
chr11_-_24681292 1.80 ENSDART00000089601
olfml3b
olfactomedin-like 3b
chr16_+_5774977 1.80 ENSDART00000134202
ccka
cholecystokinin a
chr23_-_45705525 1.80 ENSDART00000148959
ednrab
endothelin receptor type Ab
chr23_-_46040618 1.78 ENSDART00000161415
CABZ01080918.1

chr20_+_48782068 1.75 ENSDART00000159275
nkx2.2b
NK2 homeobox 2b
chr4_+_38344 1.75 ENSDART00000170197
ENSDART00000175348
phtf2
putative homeodomain transcription factor 2
chr24_-_32408404 1.75 ENSDART00000144157
si:ch211-56a11.2
si:ch211-56a11.2
chr16_-_560574 1.74 ENSDART00000148452
irx2a
iroquois homeobox 2a
chr2_-_31302615 1.73 ENSDART00000034784
ENSDART00000060812
adcyap1b
adenylate cyclase activating polypeptide 1b
chr23_-_15216654 1.72 ENSDART00000131649
sulf2b
sulfatase 2b
chr3_+_28953274 1.72 ENSDART00000133528
ENSDART00000103602
lgals2a
lectin, galactoside-binding, soluble, 2a
chr19_-_30404096 1.72 ENSDART00000103475
agr2
anterior gradient 2
chr19_+_58954 1.69 ENSDART00000162379
col14a1b
collagen, type XIV, alpha 1b
chr22_-_2886937 1.69 ENSDART00000063533
aqp12
aquaporin 12
chr23_-_24488696 1.69 ENSDART00000155593
tmem82
transmembrane protein 82
chr8_+_46217861 1.68 ENSDART00000038790
angptl7
angiopoietin-like 7
chr3_-_36260102 1.68 ENSDART00000126588
rac3a
Rac family small GTPase 3a
chr3_-_30941362 1.65 ENSDART00000076830
coro1a
coronin, actin binding protein, 1A
chr13_-_36703164 1.65 ENSDART00000044357
cdkl1
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr1_+_53945934 1.64 ENSDART00000052838
acta1a
actin, alpha 1a, skeletal muscle
chr10_+_37145007 1.64 ENSDART00000131777
cuedc1a
CUE domain containing 1a
chr18_+_2837563 1.64 ENSDART00000171495
ENSDART00000160228
fam168a
family with sequence similarity 168, member A
chr16_+_33655890 1.63 ENSDART00000143757
fhl3a
four and a half LIM domains 3a
chr9_-_23033818 1.62 ENSDART00000022392
rnd3b
Rho family GTPase 3b
chr2_-_48196092 1.61 ENSDART00000139944
snorc
secondary ossification center associated regulator of chondrocyte maturation
chr15_-_29388012 1.61 ENSDART00000115032
serpinh1b
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr10_+_43994471 1.60 ENSDART00000138242
ENSDART00000186359
cldn5b
claudin 5b
chr18_+_48423973 1.59 ENSDART00000184233
ENSDART00000147074
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr8_-_49431939 1.58 ENSDART00000011453
ENSDART00000088240
ENSDART00000114173
sypb
synaptophysin b
chr7_+_26716321 1.58 ENSDART00000189750
cd82a
CD82 molecule a
chr21_+_27416284 1.56 ENSDART00000077593
ENSDART00000108763
cfb
complement factor B
chr19_-_9712530 1.54 ENSDART00000134816
slc2a3a
solute carrier family 2 (facilitated glucose transporter), member 3a
chr6_-_40058686 1.54 ENSDART00000103240
uroc1
urocanate hydratase 1
chr23_-_31372639 1.54 ENSDART00000179908
ENSDART00000135620
ENSDART00000053367
hmgn3
high mobility group nucleosomal binding domain 3
chr18_+_22302635 1.53 ENSDART00000141051
carmil2
capping protein regulator and myosin 1 linker 2
chr22_+_11756040 1.52 ENSDART00000105808
krt97
keratin 97
chr23_-_39636195 1.52 ENSDART00000144439
vwa1
von Willebrand factor A domain containing 1
chr18_+_50801307 1.51 ENSDART00000174126
tspan4a
tetraspanin 4a
chr9_-_1951144 1.51 ENSDART00000082355
hoxd4a
homeobox D4a
chr10_-_17103651 1.50 ENSDART00000108959
RNF208
ring finger protein 208
chr19_+_30662529 1.50 ENSDART00000175662
fam49al
family with sequence similarity 49, member A-like
chr7_-_26924903 1.50 ENSDART00000124363
alx4a
ALX homeobox 4a
chr8_+_39634114 1.50 ENSDART00000144293
msi1
musashi RNA-binding protein 1
chr11_+_11201096 1.48 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myom2a
myomesin 2a
chr10_-_31782616 1.48 ENSDART00000128839
fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr18_-_48492951 1.48 ENSDART00000146346
kcnj1a.6
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
chr15_-_21165237 1.48 ENSDART00000157069
A2ML1 (1 of many)
si:ch211-212c13.8
chr5_-_41831646 1.48 ENSDART00000134326
si:dkey-65b12.6
si:dkey-65b12.6
chr6_-_609880 1.47 ENSDART00000149248
ENSDART00000148867
ENSDART00000149414
ENSDART00000148552
ENSDART00000148391
lgals2b
lectin, galactoside-binding, soluble, 2b
chr8_+_24745041 1.47 ENSDART00000148872
slc16a4
solute carrier family 16, member 4
chr1_+_46194333 1.46 ENSDART00000010894
sox1b
SRY (sex determining region Y)-box 1b
chr7_-_4036184 1.45 ENSDART00000019949
ndrg2
NDRG family member 2
chr15_+_24644016 1.43 ENSDART00000043292
smtnl
smoothelin, like
chr19_-_30403922 1.43 ENSDART00000181841
agr2
anterior gradient 2
chr9_-_710896 1.42 ENSDART00000180478
ndufb3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3
chr15_+_5923851 1.41 ENSDART00000152520
ENSDART00000145827
ENSDART00000121529
sh3bgr
SH3 domain binding glutamate-rich protein
chr11_-_30138299 1.41 ENSDART00000172106
scml2
Scm polycomb group protein like 2
chr10_+_22775253 1.41 ENSDART00000190141
tmem88a
transmembrane protein 88 a
chr24_-_12938922 1.41 ENSDART00000024084
pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr14_+_36246726 1.40 ENSDART00000105602
elovl6
ELOVL fatty acid elongase 6
chr10_+_6318227 1.39 ENSDART00000170872
ENSDART00000162428
ENSDART00000158994
tpm2
tropomyosin 2 (beta)
chr18_-_15373620 1.39 ENSDART00000031752
rfx4
regulatory factor X, 4
chr14_-_215051 1.39 ENSDART00000054822
nkx3.2
NK3 homeobox 2
chr18_-_16123222 1.38 ENSDART00000061189
sspn
sarcospan (Kras oncogene-associated gene)
chr15_+_24644251 1.38 ENSDART00000181660
smtnl
smoothelin, like
chr23_+_43954809 1.38 ENSDART00000164080
corin
corin, serine peptidase
chr6_-_60031693 1.38 ENSDART00000160275
CABZ01079262.1

chr20_-_52314299 1.37 ENSDART00000038157
naprt
nicotinate phosphoribosyltransferase
chr13_+_22480496 1.36 ENSDART00000136863
ENSDART00000131870
ENSDART00000078720
ENSDART00000078740
ENSDART00000139218
ldb3a
LIM domain binding 3a
chr5_+_38276582 1.36 ENSDART00000158532
gnb2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr23_-_11870962 1.36 ENSDART00000143481
si:dkey-178k16.1
si:dkey-178k16.1
chr13_-_39947335 1.35 ENSDART00000056996
sfrp5
secreted frizzled-related protein 5
chr16_-_2414063 1.34 ENSDART00000073621
zgc:152945
zgc:152945
chr18_-_48517040 1.33 ENSDART00000143645
kcnj1a.3
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 3
chr18_+_30508729 1.33 ENSDART00000185140
cox4i1
cytochrome c oxidase subunit IV isoform 1
chr6_-_40429411 1.32 ENSDART00000156005
ENSDART00000156357
si:dkey-28n18.9
si:dkey-28n18.9
chr19_+_4916233 1.32 ENSDART00000159512
ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr8_+_48613040 1.32 ENSDART00000121432
nppa
natriuretic peptide A
chr10_-_22797959 1.32 ENSDART00000183269
pcolcea
procollagen C-endopeptidase enhancer a
chr6_+_48618512 1.32 ENSDART00000111190
FAM19A3
si:dkey-238f9.1
chr13_-_16222388 1.32 ENSDART00000182861
zgc:110045
zgc:110045
chr1_-_49498116 1.31 ENSDART00000137357
zgc:175214
zgc:175214
chr23_-_26536055 1.31 ENSDART00000182719
si:dkey-205h13.2
si:dkey-205h13.2
chr7_+_26029672 1.30 ENSDART00000101126
alox12
arachidonate 12-lipoxygenase
chr1_+_29759678 1.30 ENSDART00000054059
ENSDART00000101856
cpb2
carboxypeptidase B2 (plasma)
chr23_+_24124684 1.30 ENSDART00000144478
si:dkey-21o19.2
si:dkey-21o19.2
chr21_+_25688388 1.29 ENSDART00000125709
bicdl2
bicaudal-D-related protein 2
chr13_-_31452516 1.29 ENSDART00000193268
rtn1a
reticulon 1a
chr1_-_22757145 1.29 ENSDART00000134719
prom1b
prominin 1 b
chr3_+_1182315 1.29 ENSDART00000055430
ndufa6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6
chr16_-_38921745 1.28 ENSDART00000131409
BX571839.1

chr14_+_33722950 1.28 ENSDART00000075312
apln
apelin
chr9_-_22834860 1.27 ENSDART00000146486
neb
nebulin
chr8_-_16697912 1.27 ENSDART00000076542
rpe65b
retinal pigment epithelium-specific protein 65b
chr20_+_2281933 1.26 ENSDART00000137579
si:ch73-18b11.2
si:ch73-18b11.2
chr6_+_41463786 1.26 ENSDART00000065006
twf2a
twinfilin actin-binding protein 2a
chr6_+_28124393 1.26 ENSDART00000089195
gpr17
G protein-coupled receptor 17
chr23_-_45504991 1.25 ENSDART00000148761
col24a1
collagen type XXIV alpha 1
chr2_-_55853943 1.25 ENSDART00000122576
rx2
retinal homeobox gene 2
chr23_-_15330168 1.24 ENSDART00000035865
ENSDART00000143635
sulf2b
sulfatase 2b
chr11_+_30295582 1.24 ENSDART00000122424
ugt1b7
UDP glucuronosyltransferase 1 family, polypeptide B7
chr4_-_16853464 1.24 ENSDART00000125743
ENSDART00000164570
slc25a3a
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3a
chr20_-_16906623 1.24 ENSDART00000012859
ENSDART00000171628
psma6b
proteasome subunit alpha 6b
chr15_-_2652640 1.21 ENSDART00000146094
cldnf
claudin f
chr20_+_40150612 1.20 ENSDART00000143680
ENSDART00000109681
ENSDART00000101041
ENSDART00000121818
trdn
triadin
chr2_-_38000276 1.20 ENSDART00000034790
pcp4l1
Purkinje cell protein 4 like 1
chr4_-_7212875 1.19 ENSDART00000161297
lrrn3b
leucine rich repeat neuronal 3b
chr20_-_24122881 1.19 ENSDART00000131857
bach2b
BTB and CNC homology 1, basic leucine zipper transcription factor 2b
chr8_+_39760258 1.19 ENSDART00000037914
cox6a1
cytochrome c oxidase subunit VIa polypeptide 1
chr20_+_26349002 1.18 ENSDART00000152842
syne1a
spectrin repeat containing, nuclear envelope 1a
chr25_-_15214161 1.18 ENSDART00000031499
wt1a
wilms tumor 1a
chr10_+_13209580 1.18 ENSDART00000000887
ENSDART00000136932
rassf6
Ras association (RalGDS/AF-6) domain family 6
chr17_+_53425037 1.17 ENSDART00000154983
fabp10b
fatty acid binding protein 10b, liver basic

Network of associatons between targets according to the STRING database.

First level regulatory network of esr1+esr2a+esr2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0046415 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
0.8 2.5 GO:0070314 G1 to G0 transition(GO:0070314)
0.7 2.9 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.7 2.8 GO:0051503 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.6 2.6 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.6 1.8 GO:0050995 negative regulation of lipid transport(GO:0032369) negative regulation of lipid catabolic process(GO:0050995)
0.6 4.1 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.6 3.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.5 3.3 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.5 1.6 GO:0090131 mesenchyme migration(GO:0090131)
0.5 2.1 GO:0061549 sympathetic ganglion development(GO:0061549)
0.5 1.5 GO:0043606 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.5 1.5 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.5 1.4 GO:1901295 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.5 2.3 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
0.4 1.3 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.4 1.3 GO:1905072 cardiac jelly development(GO:1905072)
0.4 3.5 GO:0035777 pronephric distal tubule development(GO:0035777)
0.4 1.3 GO:0042730 fibrinolysis(GO:0042730)
0.4 1.7 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.4 1.6 GO:0009098 leucine biosynthetic process(GO:0009098)
0.4 1.2 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.4 4.1 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.4 1.1 GO:0015990 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.4 1.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.4 1.8 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.4 46.4 GO:0002088 lens development in camera-type eye(GO:0002088)
0.4 1.4 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) response to dexamethasone(GO:0071548)
0.3 3.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.3 1.0 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 4.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.3 1.3 GO:0016122 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.3 2.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.3 1.9 GO:0033032 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.3 2.4 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.3 1.2 GO:0061032 visceral serous pericardium development(GO:0061032) glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.3 0.9 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519)
0.3 1.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.3 1.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.3 0.8 GO:0051230 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.2 0.7 GO:0035776 pronephric proximal tubule development(GO:0035776) proximal straight tubule development(GO:0072020)
0.2 0.7 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.2 0.7 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.2 0.7 GO:0007414 axonal defasciculation(GO:0007414)
0.2 0.7 GO:0055070 copper ion homeostasis(GO:0055070)
0.2 1.7 GO:0010595 positive regulation of endothelial cell migration(GO:0010595)
0.2 0.9 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 0.2 GO:0090008 hypoblast development(GO:0090008)
0.2 0.9 GO:0003348 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.2 1.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.2 1.7 GO:0090303 positive regulation of wound healing(GO:0090303)
0.2 0.9 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.2 0.6 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.2 1.3 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.2 0.8 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 3.5 GO:1903672 positive regulation of sprouting angiogenesis(GO:1903672)
0.2 0.6 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.2 1.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.2 3.5 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.2 3.1 GO:0007418 ventral midline development(GO:0007418)
0.2 0.9 GO:2000328 regulation of T-helper 17 type immune response(GO:2000316) negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320) regulation of T-helper 17 cell lineage commitment(GO:2000328) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.2 2.5 GO:0014846 vascular endothelial growth factor production(GO:0010573) regulation of vascular endothelial growth factor production(GO:0010574) positive regulation of vascular endothelial growth factor production(GO:0010575) esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2 0.5 GO:0032677 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.2 0.5 GO:1901881 positive regulation of protein depolymerization(GO:1901881) regulation of barbed-end actin filament capping(GO:2000812)
0.2 0.5 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 2.4 GO:0046549 retinal cone cell development(GO:0046549)
0.2 0.7 GO:0044068 modification by symbiont of host morphology or physiology(GO:0044003) modulation by symbiont of host cellular process(GO:0044068)
0.2 3.4 GO:0006825 copper ion transport(GO:0006825)
0.2 0.7 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.2 1.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 0.6 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.2 0.6 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.1 0.6 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 3.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 2.5 GO:0016203 muscle attachment(GO:0016203)
0.1 2.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.4 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.5 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.1 3.1 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 1.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.7 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1 0.5 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 1.8 GO:0043114 regulation of vascular permeability(GO:0043114)
0.1 1.2 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.7 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.1 1.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.5 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 0.8 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.1 1.7 GO:0035778 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014)
0.1 0.3 GO:1901232 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.1 0.7 GO:0006545 glycine biosynthetic process(GO:0006545)
0.1 1.9 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.5 GO:0050927 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.1 0.9 GO:0021794 thalamus development(GO:0021794)
0.1 0.2 GO:0072679 thymocyte migration(GO:0072679)
0.1 0.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.4 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.1 2.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 1.3 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 1.0 GO:0001964 startle response(GO:0001964)
0.1 0.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 3.6 GO:0060840 artery development(GO:0060840)
0.1 2.2 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.9 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 1.7 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.7 GO:0021588 cerebellum formation(GO:0021588)
0.1 5.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.7 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 0.9 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 1.0 GO:0023058 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) G-protein coupled receptor internalization(GO:0002031) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.1 1.0 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 1.0 GO:0021754 facial nucleus development(GO:0021754)
0.1 0.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.6 GO:0090075 relaxation of muscle(GO:0090075)
0.1 0.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 1.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 1.4 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.3 GO:0045730 respiratory burst(GO:0045730)
0.1 1.0 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 0.4 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.1 0.9 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 0.2 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 0.4 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 0.9 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 1.0 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 7.5 GO:0002040 sprouting angiogenesis(GO:0002040)
0.1 1.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.6 GO:0006868 glutamine transport(GO:0006868)
0.1 1.6 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 0.3 GO:0051031 tRNA transport(GO:0051031)
0.1 0.4 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 0.6 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 0.5 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.7 GO:0046620 regulation of organ growth(GO:0046620)
0.1 0.3 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.1 1.6 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.7 GO:0019233 sensory perception of pain(GO:0019233)
0.1 0.8 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 1.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 5.0 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.1 1.9 GO:0007586 digestion(GO:0007586)
0.1 6.1 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 1.6 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.1 0.8 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.4 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.8 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 1.1 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.3 GO:0090497 mesenchymal cell migration(GO:0090497)
0.0 0.5 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.4 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 1.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.0 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.2 GO:0070376 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.0 1.1 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.6 GO:0006284 base-excision repair(GO:0006284)
0.0 1.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.9 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 1.0 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.3 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.9 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.7 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.5 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.7 GO:0070672 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 0.7 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.1 GO:0046104 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.1 GO:0097581 lamellipodium organization(GO:0097581) regulation of lamellipodium organization(GO:1902743)
0.0 0.4 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.7 GO:0015671 gas transport(GO:0015669) oxygen transport(GO:0015671)
0.0 0.6 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.5 GO:0030317 sperm motility(GO:0030317)
0.0 0.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.6 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.9 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.3 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.0 0.2 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.3 GO:0060612 adipose tissue development(GO:0060612)
0.0 1.1 GO:0001570 vasculogenesis(GO:0001570)
0.0 0.3 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.5 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.1 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.2 GO:0046294 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.0 2.1 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.1 GO:0044650 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.0 0.1 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.0 5.9 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 1.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.3 GO:0050936 xanthophore differentiation(GO:0050936)
0.0 0.5 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.5 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.3 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.1 GO:0003272 endocardial cushion formation(GO:0003272) protein kinase D signaling(GO:0089700)
0.0 0.3 GO:0021984 adenohypophysis development(GO:0021984)
0.0 2.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0009251 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.4 GO:0015701 bicarbonate transport(GO:0015701)
0.0 2.6 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 0.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.4 GO:1904894 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0 0.2 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 2.0 GO:0001817 regulation of cytokine production(GO:0001817)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 1.2 GO:0035966 response to topologically incorrect protein(GO:0035966)
0.0 1.3 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.0 1.6 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.1 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.2 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.3 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 1.0 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.1 GO:1902667 regulation of axon guidance(GO:1902667)
0.0 0.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 2.5 GO:0042391 regulation of membrane potential(GO:0042391)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 2.2 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 2.0 GO:0016049 cell growth(GO:0016049)
0.0 0.5 GO:0048048 embryonic eye morphogenesis(GO:0048048)
0.0 1.7 GO:0006936 muscle contraction(GO:0006936)
0.0 0.3 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.1 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.0 0.1 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.2 GO:0043049 otic placode formation(GO:0043049) ectodermal placode formation(GO:0060788)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.5 GO:0048545 response to steroid hormone(GO:0048545)
0.0 0.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.4 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.6 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.5 GO:0031638 zymogen activation(GO:0031638)
0.0 0.1 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.4 GO:0098642 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.4 3.0 GO:0071914 prominosome(GO:0071914)
0.4 3.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.3 2.0 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.3 3.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 0.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 0.7 GO:1990909 Wnt signalosome(GO:1990909)
0.2 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.2 4.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 1.1 GO:0005581 collagen trimer(GO:0005581)
0.1 0.6 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 0.6 GO:0005579 membrane attack complex(GO:0005579)
0.1 2.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.7 GO:0043034 costamere(GO:0043034)
0.1 1.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.8 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.1 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.9 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.7 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.2 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.4 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.6 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 1.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 10.6 GO:0030018 Z disc(GO:0030018)
0.1 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.6 GO:0005869 dynactin complex(GO:0005869)
0.1 1.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 4.2 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.5 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.7 GO:0031045 dense core granule(GO:0031045)
0.1 0.9 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 1.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.4 GO:0097224 sperm connecting piece(GO:0097224)
0.1 7.9 GO:0030017 sarcomere(GO:0030017)
0.1 3.4 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 8.7 GO:0005882 intermediate filament(GO:0005882)
0.1 5.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.4 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 3.2 GO:0043204 perikaryon(GO:0043204)
0.1 0.5 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 0.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.4 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.2 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.5 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 1.0 GO:0031209 SCAR complex(GO:0031209)
0.1 0.7 GO:0061617 MICOS complex(GO:0061617)
0.1 1.5 GO:0043195 terminal bouton(GO:0043195)
0.1 1.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 20.4 GO:0031012 extracellular matrix(GO:0031012)
0.1 3.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.8 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.3 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.1 GO:0032433 filopodium tip(GO:0032433)
0.0 0.5 GO:0043209 myelin sheath(GO:0043209)
0.0 3.2 GO:0005884 actin filament(GO:0005884)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 49.3 GO:0005576 extracellular region(GO:0005576)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.9 GO:0008305 integrin complex(GO:0008305)
0.0 0.7 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 1.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.9 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.0 0.7 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.6 GO:0030141 secretory granule(GO:0030141)
0.0 0.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.5 GO:0016605 PML body(GO:0016605)
0.0 1.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0048030 disaccharide binding(GO:0048030)
0.7 2.8 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.7 3.4 GO:0016531 copper chaperone activity(GO:0016531)
0.6 5.9 GO:0016936 galactoside binding(GO:0016936)
0.6 47.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.5 3.7 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.4 1.7 GO:0016521 pituitary adenylate cyclase activating polypeptide activity(GO:0016521)
0.4 1.3 GO:0031704 apelin receptor binding(GO:0031704)
0.4 3.8 GO:0005113 patched binding(GO:0005113)
0.4 1.6 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.4 1.1 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.4 1.5 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.4 4.1 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.4 1.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.3 1.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 1.6 GO:0051430 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.3 1.3 GO:0050251 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.3 2.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 4.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.3 1.9 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.3 4.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.3 0.3 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429)
0.3 2.8 GO:0016805 dipeptidase activity(GO:0016805)
0.3 4.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.3 2.4 GO:0019841 retinol binding(GO:0019841)
0.3 1.8 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.3 1.8 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 1.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.2 0.6 GO:0060175 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.2 1.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 0.8 GO:0004925 prolactin receptor activity(GO:0004925)
0.2 1.0 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.2 1.8 GO:0015250 water channel activity(GO:0015250)
0.2 0.6 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.2 1.4 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.2 1.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 0.7 GO:0044548 S100 protein binding(GO:0044548)
0.2 3.5 GO:0001671 ATPase activator activity(GO:0001671)
0.2 2.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 0.8 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 0.5 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 4.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.9 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.7 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 2.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.6 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 5.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 1.7 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 0.4 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 0.7 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.4 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 1.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 1.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.5 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 0.6 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.3 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 1.5 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.1 0.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 2.4 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 2.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 2.2 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.7 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.1 0.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 1.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 1.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.6 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.7 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 1.4 GO:0038191 neuropilin binding(GO:0038191)
0.1 2.4 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 1.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.9 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.4 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.4 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.1 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 2.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 5.0 GO:0005178 integrin binding(GO:0005178)
0.1 1.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.4 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.1 1.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.1 0.4 GO:2001070 starch binding(GO:2001070)
0.1 4.0 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 9.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 1.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.6 GO:0004985 opioid receptor activity(GO:0004985)
0.1 2.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.6 GO:0005518 collagen binding(GO:0005518)
0.1 0.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.5 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.3 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 4.1 GO:0008201 heparin binding(GO:0008201)
0.1 0.6 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.4 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.2 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.7 GO:0009055 electron carrier activity(GO:0009055)
0.0 1.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.3 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 15.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0060182 apelin receptor activity(GO:0060182)
0.0 0.6 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 1.4 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.9 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 3.1 GO:0045296 cadherin binding(GO:0045296)
0.0 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:1903924 estradiol binding(GO:1903924)
0.0 0.7 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 1.6 GO:0016859 cis-trans isomerase activity(GO:0016859)
0.0 1.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.5 GO:0019894 kinesin binding(GO:0019894)
0.0 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 1.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 1.3 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.2 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.5 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 9.7 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 3.2 GO:0005267 potassium channel activity(GO:0005267)
0.0 1.2 GO:0019838 growth factor binding(GO:0019838)
0.0 0.1 GO:0017113 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0 0.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.7 GO:0005507 copper ion binding(GO:0005507)
0.0 1.4 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.1 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.7 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 0.7 GO:0009975 cyclase activity(GO:0009975)
0.0 3.6 GO:0003779 actin binding(GO:0003779)
0.0 0.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.0 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.5 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 0.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 5.4 NABA COLLAGENS Genes encoding collagen proteins
0.1 3.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.0 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 0.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 8.1 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.7 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 6.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 2.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 2.8 NABA MATRISOME Ensemble of genes encoding extracellular matrix and extracellular matrix-associated proteins
0.0 0.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.5 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 2.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 11.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 2.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 4.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 2.7 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.2 1.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 6.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 0.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 0.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.4 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 1.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.0 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 2.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 3.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels