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PRJNA195909:zebrafish embryo and larva development

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Results for figla

Z-value: 1.10

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Transcription factors associated with figla

Gene Symbol Gene ID Gene Info
figla
ENSDARG00000087166 folliculogenesis specific bHLH transcription factor
figla
ENSDARG00000115572 folliculogenesis specific bHLH transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
figladr11_v1_chr5_-_13848296_138482960.863.1e-03Click!

Activity profile of figla motif

Sorted Z-values of figla motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_58751504 2.98 ENSDART00000024185
zgc:56231
zgc:56231
chr5_+_57924611 2.67 ENSDART00000050949
btg4
B-cell translocation gene 4
chr10_-_25217347 2.50 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr2_-_50225411 2.33 ENSDART00000147117
ENSDART00000000042
mcm6l
MCM6 minichromosome maintenance deficient 6, like
chr15_+_38299385 2.19 ENSDART00000142403
si:dkey-24p1.6
si:dkey-24p1.6
chr16_-_42066523 2.08 ENSDART00000180538
ENSDART00000058620
zp3d.1
zona pellucida glycoprotein 3d tandem duplicate 1
chr8_+_45334255 1.93 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr7_+_57089354 1.93 ENSDART00000140702
scamp2l
secretory carrier membrane protein 2, like
chr21_-_34261677 1.82 ENSDART00000124649
ENSDART00000172381
ENSDART00000064320
alg13
ALG13, UDP-N-acetylglucosaminyltransferase subunit
chr7_+_67699178 1.82 ENSDART00000160086
zgc:162592
zgc:162592
chr15_+_38299563 1.79 ENSDART00000099375
si:dkey-24p1.6
si:dkey-24p1.6
chr20_-_43743700 1.75 ENSDART00000100620
si:dkeyp-50f7.2
si:dkeyp-50f7.2
chr2_+_27855102 1.73 ENSDART00000150330
buc
bucky ball
chr5_-_23696926 1.68 ENSDART00000021462
rnf128a
ring finger protein 128a
chr17_-_25331439 1.68 ENSDART00000155422
ENSDART00000082324
zpcx
zona pellucida protein C
chr7_-_48251234 1.62 ENSDART00000024062
ENSDART00000098904
cpeb1b
cytoplasmic polyadenylation element binding protein 1b
chr2_+_27855346 1.60 ENSDART00000175159
ENSDART00000192645
buc
bucky ball
chr11_-_6452444 1.45 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
larp6b
La ribonucleoprotein domain family, member 6b
chr5_-_30080332 1.41 ENSDART00000140049
bco2a
beta-carotene oxygenase 2a
chr10_-_24784446 1.41 ENSDART00000140877
si:ch1073-15f19.2
si:ch1073-15f19.2
chr7_+_67699009 1.41 ENSDART00000192810
zgc:162592
zgc:162592
chr12_-_4301234 1.40 ENSDART00000152377
ENSDART00000152521
ca15b
carbonic anhydrase XVb
chr12_-_30359031 1.40 ENSDART00000192628
tdrd1
tudor domain containing 1
chr16_-_47381519 1.39 ENSDART00000032188
ENSDART00000150136
si:dkey-256h2.1
si:dkey-256h2.1
chr4_-_277081 1.35 ENSDART00000166174
si:ch73-252i11.1
si:ch73-252i11.1
chr2_-_57469115 1.26 ENSDART00000192201
pias4b
protein inhibitor of activated STAT, 4b
chr12_-_30358836 1.26 ENSDART00000152878
tdrd1
tudor domain containing 1
chr3_+_26245731 1.22 ENSDART00000103734
atad5a
ATPase family, AAA domain containing 5a
chr25_-_17587785 1.21 ENSDART00000073679
ENSDART00000146851
zgc:66449
zgc:66449
chr19_+_7636941 1.20 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cgnb
cingulin b
chr24_-_2423791 1.20 ENSDART00000190402
rreb1a
ras responsive element binding protein 1a
chr13_+_31716820 1.16 ENSDART00000034745
prkcha
protein kinase C, eta, a
chr1_-_53468160 1.14 ENSDART00000143349
zgc:66455
zgc:66455
chr5_-_15494164 1.14 ENSDART00000140668
ENSDART00000188076
ENSDART00000085943
taok3a
TAO kinase 3a
chr1_-_6085750 1.14 ENSDART00000138891
si:ch1073-345a8.1
si:ch1073-345a8.1
chr24_-_10394277 1.11 ENSDART00000127568
ankha
ANKH inorganic pyrophosphate transport regulator a
chr10_-_1961576 1.10 ENSDART00000042441
tdgf1
teratocarcinoma-derived growth factor 1
chr5_+_58679071 1.08 ENSDART00000019561
zgc:171734
zgc:171734
chr6_+_153146 1.07 ENSDART00000097468
zglp1
zinc finger, GATA-like protein 1
chr16_+_43077909 1.06 ENSDART00000014140
rundc3b
RUN domain containing 3b
chr10_-_31805923 1.05 ENSDART00000077785
vps26bl
vacuolar protein sorting 26 homolog B, like
chr10_-_1961930 1.03 ENSDART00000122446
tdgf1
teratocarcinoma-derived growth factor 1
chr14_+_22297257 1.00 ENSDART00000113676
atp10b
ATPase phospholipid transporting 10B
chr5_-_29531948 0.99 ENSDART00000098360
arrdc1a
arrestin domain containing 1a
chr14_-_7409364 0.99 ENSDART00000036463
dnd1
DND microRNA-mediated repression inhibitor 1
chr2_-_17114852 0.96 ENSDART00000006549
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr17_+_1360192 0.96 ENSDART00000184561
siva1
SIVA1, apoptosis-inducing factor
chr9_-_5351017 0.95 ENSDART00000082260
abhd13
abhydrolase domain containing 13
chr13_+_35955562 0.95 ENSDART00000137377
si:ch211-67f13.7
si:ch211-67f13.7
chr22_-_10891213 0.92 ENSDART00000145229
arhgef18b
rho/rac guanine nucleotide exchange factor (GEF) 18b
chr14_-_32631013 0.91 ENSDART00000176815
atp11c
ATPase phospholipid transporting 11C
chr13_+_39282477 0.90 ENSDART00000132198
si:dkey-85a20.4
si:dkey-85a20.4
chr23_+_25893020 0.90 ENSDART00000144769
pkig
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr2_-_57916317 0.90 ENSDART00000183930
si:dkeyp-68b7.7
si:dkeyp-68b7.7
chr7_+_57088920 0.88 ENSDART00000024076
scamp2l
secretory carrier membrane protein 2, like
chr14_+_24840669 0.88 ENSDART00000106039
arhgef37
Rho guanine nucleotide exchange factor (GEF) 37
chr15_-_5624361 0.87 ENSDART00000176446
ENSDART00000114410
wdr62
WD repeat domain 62
chr11_+_31730680 0.87 ENSDART00000145497
diaph3
diaphanous-related formin 3
chr2_+_1988036 0.86 ENSDART00000155956
ssx2ipa
synovial sarcoma, X breakpoint 2 interacting protein a
chr15_+_29024895 0.86 ENSDART00000141164
ENSDART00000144126
si:ch211-137a8.2
si:ch211-137a8.2
chr10_+_37173029 0.85 ENSDART00000136510
ksr1a
kinase suppressor of ras 1a
chr19_-_10214264 0.82 ENSDART00000053300
ENSDART00000148225
znf865
zinc finger protein 865
chr6_-_12912606 0.82 ENSDART00000164640
ical1
islet cell autoantigen 1-like
chr3_-_2613990 0.81 ENSDART00000137102
si:dkey-217f16.6
si:dkey-217f16.6
chr14_+_35464994 0.79 ENSDART00000115307
si:ch211-203d1.3
si:ch211-203d1.3
chr22_-_17677947 0.79 ENSDART00000139911
tjp3
tight junction protein 3
chr2_-_17115256 0.78 ENSDART00000190488
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr4_-_858434 0.77 ENSDART00000006961
sobpb
sine oculis binding protein homolog (Drosophila) b
chr7_+_67748939 0.76 ENSDART00000162978
dhx38
DEAH (Asp-Glu-Ala-His) box polypeptide 38
chr6_-_8360918 0.76 ENSDART00000004716
acp5a
acid phosphatase 5a, tartrate resistant
chr12_-_23365737 0.76 ENSDART00000170376
mpp7a
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr13_-_21672131 0.75 ENSDART00000067537
elovl6l
ELOVL family member 6, elongation of long chain fatty acids like
chr3_+_34121156 0.75 ENSDART00000174929
aldh3b1
aldehyde dehydrogenase 3 family, member B1
chr17_-_36860988 0.73 ENSDART00000154981
senp6b
SUMO1/sentrin specific peptidase 6b
chr9_-_28939181 0.73 ENSDART00000101276
ENSDART00000135334
epb41l5
erythrocyte membrane protein band 4.1 like 5
chr20_-_16498991 0.72 ENSDART00000104137
ches1
checkpoint suppressor 1
chr4_-_13614797 0.72 ENSDART00000138366
ENSDART00000165212
irf5
interferon regulatory factor 5
chr14_-_16810401 0.71 ENSDART00000158396
ENSDART00000170758
tcirg1b
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr19_+_43684376 0.71 ENSDART00000051723
si:ch211-193k19.1
si:ch211-193k19.1
chr13_-_14926318 0.70 ENSDART00000142785
cdc25b
cell division cycle 25B
chr7_-_18881358 0.70 ENSDART00000021502
mllt3
MLLT3, super elongation complex subunit
chr25_-_24240797 0.70 ENSDART00000132790
spty2d1
SPT2 chromatin protein domain containing 1
chr10_-_14929630 0.69 ENSDART00000121892
ENSDART00000044756
ENSDART00000128579
ENSDART00000147653
smad2
SMAD family member 2
chr2_+_43204919 0.69 ENSDART00000160077
ENSDART00000018729
ENSDART00000129134
ENSDART00000056402
pard3ab
par-3 family cell polarity regulator alpha, b
chr23_-_19831739 0.67 ENSDART00000125066
haus7
HAUS augmin-like complex, subunit 7
chr6_-_41135215 0.67 ENSDART00000001861
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr24_-_34335265 0.67 ENSDART00000128690
agap3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr3_+_42923275 0.65 ENSDART00000168228
tmem184a
transmembrane protein 184a
chr9_-_29578037 0.64 ENSDART00000189026
cenpj
centromere protein J
chr5_-_29152457 0.64 ENSDART00000078469
noxa1
NADPH oxidase activator 1
chr23_-_19684721 0.64 ENSDART00000184325
zgc:193598
zgc:193598
chr18_+_22220656 0.64 ENSDART00000191862
ripor1
RHO family interacting cell polarization regulator 1
chr15_+_34963316 0.64 ENSDART00000153840
si:ch73-95l15.5
si:ch73-95l15.5
chr2_+_23048620 0.63 ENSDART00000170669
csnk1g2a
casein kinase 1, gamma 2a
chr21_-_21178410 0.63 ENSDART00000185277
ENSDART00000141341
ENSDART00000145872
ENSDART00000079678
ftsj1
FtsJ RNA methyltransferase homolog 1
chr23_+_9522942 0.63 ENSDART00000137751
osbpl2b
oxysterol binding protein-like 2b
chr13_+_8892784 0.62 ENSDART00000075054
ENSDART00000143705
thada
thyroid adenoma associated
chr24_+_33802528 0.62 ENSDART00000136040
ENSDART00000147499
ENSDART00000182322
atg9b
autophagy related 9B
chr11_-_44999858 0.62 ENSDART00000167759
ENSDART00000126845
ldb1b
LIM-domain binding 1b
chr23_-_18057851 0.61 ENSDART00000173075
ENSDART00000173230
ENSDART00000173135
ENSDART00000173431
ENSDART00000173068
ENSDART00000172987
zgc:92287
zgc:92287
chr5_-_25572151 0.61 ENSDART00000144995
si:dkey-229d2.4
si:dkey-229d2.4
chr18_+_13248956 0.60 ENSDART00000080709
plcg2
phospholipase C, gamma 2
chr21_+_34981263 0.60 ENSDART00000132711
rbm11
RNA binding motif protein 11
chr25_+_27744293 0.60 ENSDART00000103519
ENSDART00000149456
wasla
Wiskott-Aldrich syndrome-like a
chr23_+_9522781 0.60 ENSDART00000136486
osbpl2b
oxysterol binding protein-like 2b
chr23_-_25686894 0.60 ENSDART00000181420
ENSDART00000088208
lrp1ab
low density lipoprotein receptor-related protein 1Ab
chr3_+_14641962 0.60 ENSDART00000091070
zgc:158403
zgc:158403
chr8_-_14554785 0.59 ENSDART00000057645
qsox1
quiescin Q6 sulfhydryl oxidase 1
chr5_+_4016271 0.59 ENSDART00000113627
ENSDART00000105832
ENSDART00000121415
ggnbp2
gametogenetin binding protein 2
chr1_+_47335038 0.59 ENSDART00000188153
bcl9
B cell CLL/lymphoma 9
chr5_-_20678300 0.59 ENSDART00000088639
wscd2
WSC domain containing 2
chr23_+_39854566 0.59 ENSDART00000190423
ENSDART00000164473
ENSDART00000161881
si:ch73-217b7.1
si:ch73-217b7.1
chr19_+_32979331 0.59 ENSDART00000078066
spire1a
spire-type actin nucleation factor 1a
chr5_+_6670945 0.59 ENSDART00000185686
pxna
paxillin a
chr21_-_21465111 0.59 ENSDART00000141487
nectin3b
nectin cell adhesion molecule 3b
chr13_-_31025505 0.59 ENSDART00000137709
wdfy4
WDFY family member 4
chr25_-_9013963 0.59 ENSDART00000073912
rag2
recombination activating gene 2
chr1_-_45584407 0.59 ENSDART00000149155
atf7ip
activating transcription factor 7 interacting protein
chr12_+_33484458 0.58 ENSDART00000000069
slc9a3r1a
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1a
chr11_-_43473824 0.58 ENSDART00000179561
tmem63bb
transmembrane protein 63Bb
chr16_+_27444098 0.57 ENSDART00000157690
invs
inversin
chr2_+_34967022 0.56 ENSDART00000134926
astn1
astrotactin 1
chr5_-_32338866 0.56 ENSDART00000017956
ENSDART00000047670
dab2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr2_-_31800521 0.56 ENSDART00000112763
retreg1
reticulophagy regulator 1
chr3_-_21061931 0.56 ENSDART00000036741
fam57ba
family with sequence similarity 57, member Ba
chr20_-_874807 0.56 ENSDART00000020506
snx14
sorting nexin 14
chr10_-_2942900 0.56 ENSDART00000002622
oclna
occludin a
chr18_+_9493720 0.56 ENSDART00000053125
sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr8_-_13735572 0.55 ENSDART00000139642
si:dkey-258f14.7
si:dkey-258f14.7
chr8_-_29822527 0.55 ENSDART00000167487
slc20a2
solute carrier family 20 (phosphate transporter), member 2
chr7_+_19552381 0.55 ENSDART00000169060
si:ch211-212k18.5
si:ch211-212k18.5
chr23_-_26880623 0.55 ENSDART00000038491
adcy6b
adenylate cyclase 6b
chr6_-_49537646 0.55 ENSDART00000180438
FO704848.1

chr18_+_45666489 0.54 ENSDART00000180147
ENSDART00000151351
prrg4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr19_+_33139164 0.54 ENSDART00000043039
fam84b
family with sequence similarity 84, member B
chr9_-_44718628 0.54 ENSDART00000059261
dusp19a
dual specificity phosphatase 19a
chr15_+_24572926 0.53 ENSDART00000155636
ENSDART00000187800
dhrs13b
dehydrogenase/reductase (SDR family) member 13b
chr11_+_6882362 0.53 ENSDART00000144181
klhl26
kelch-like family member 26
chr5_-_65121747 0.52 ENSDART00000165556
tor2a
torsin family 2, member A
chr17_-_11151655 0.51 ENSDART00000156383
CU179699.1

chr11_-_28050559 0.51 ENSDART00000136859
ece1
endothelin converting enzyme 1
chr10_-_38468847 0.51 ENSDART00000133914
gdpd5a
glycerophosphodiester phosphodiesterase domain containing 5a
chr13_-_4992395 0.51 ENSDART00000102651
nolc1
nucleolar and coiled-body phosphoprotein 1
chr5_-_22052852 0.50 ENSDART00000002938
mtmr8
myotubularin related protein 8
chr20_-_40367493 0.49 ENSDART00000075096
smpdl3a
sphingomyelin phosphodiesterase, acid-like 3A
chr8_+_10339869 0.49 ENSDART00000132253
tbc1d22b
TBC1 domain family, member 22B
chr11_-_26701611 0.49 ENSDART00000083010
acad9
acyl-CoA dehydrogenase family, member 9
chr4_-_8040436 0.49 ENSDART00000113033
si:ch211-240l19.6
si:ch211-240l19.6
chr14_-_899170 0.48 ENSDART00000165211
ENSDART00000031992
rgs14a
regulator of G protein signaling 14a
chr20_-_13625588 0.48 ENSDART00000078893
sytl3
synaptotagmin-like 3
chr23_-_31810222 0.48 ENSDART00000134319
ENSDART00000139076
hbs1l
HBS1-like translational GTPase
chr8_+_44677569 0.47 ENSDART00000191104
grk5l
G protein-coupled receptor kinase 5 like
chr16_+_26601364 0.47 ENSDART00000087537
epb41l4b
erythrocyte membrane protein band 4.1 like 4B
chr2_-_27855576 0.47 ENSDART00000121623
FO834800.1

chr5_-_64431927 0.47 ENSDART00000158248
brd3b
bromodomain containing 3b
chr11_-_11336986 0.46 ENSDART00000016677
zgc:77929
zgc:77929
chr20_+_50052627 0.46 ENSDART00000188799
cpsf2
cleavage and polyadenylation specific factor 2
chr5_+_62052538 0.45 ENSDART00000141574
si:dkey-35m8.1
si:dkey-35m8.1
chr1_+_594584 0.45 ENSDART00000135944
jam2a
junctional adhesion molecule 2a
chr20_-_26866111 0.45 ENSDART00000077767
mylk4b
myosin light chain kinase family, member 4b
chr6_-_51665454 0.45 ENSDART00000028607
chd6
chromodomain helicase DNA binding protein 6
chr25_+_18025414 0.45 ENSDART00000154488
tmtc3
transmembrane and tetratricopeptide repeat containing 3
chr8_+_25145464 0.45 ENSDART00000136505
gnai3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr5_-_69316142 0.44 ENSDART00000157238
ENSDART00000144570
smtnb
smoothelin b
chr5_+_30392148 0.44 ENSDART00000086765
stk36
serine/threonine kinase 36 (fused homolog, Drosophila)
chr6_-_55423220 0.44 ENSDART00000158929
ctsa
cathepsin A
chr1_-_18752981 0.43 ENSDART00000188146
ENSDART00000193094
tbc1d1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr22_+_7480465 0.43 ENSDART00000034545
CELA1 (1 of many)
zgc:92745
chr1_-_55058795 0.43 ENSDART00000187293
peli1a
pellino E3 ubiquitin protein ligase 1a
chr21_+_17016337 0.42 ENSDART00000065755
gpn3
GPN-loop GTPase 3
chr4_-_16658514 0.42 ENSDART00000133837
dennd5b
DENN/MADD domain containing 5B
chr14_+_32964 0.42 ENSDART00000166173
lyar
Ly1 antibody reactive homolog (mouse)
chr14_-_33278084 0.42 ENSDART00000132850
stard14
START domain containing 14
chr11_+_13423776 0.42 ENSDART00000102553
homer3b
homer scaffolding protein 3b
chr17_+_5976683 0.42 ENSDART00000110276
zgc:194275
zgc:194275
chr5_+_50879545 0.41 ENSDART00000128402
nol6
nucleolar protein 6 (RNA-associated)
chr23_-_22113455 0.41 ENSDART00000142474
phc2a
polyhomeotic homolog 2a (Drosophila)
chr17_-_21162821 0.41 ENSDART00000157283
abhd12
abhydrolase domain containing 12
chr22_-_26251563 0.41 ENSDART00000060888
ENSDART00000142821
ccdc130
coiled-coil domain containing 130
chr18_+_45573416 0.41 ENSDART00000132184
ENSDART00000145288
kifc3
kinesin family member C3
chr5_+_31959954 0.41 ENSDART00000142826
myo1hb
myosin IHb
chr18_-_7948188 0.41 ENSDART00000091805
shank3a
SH3 and multiple ankyrin repeat domains 3a
chr25_+_15938880 0.40 ENSDART00000089035
ppfibp2b
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr14_-_45551572 0.40 ENSDART00000111410
ganab
glucosidase, alpha; neutral AB
chr6_-_13709591 0.40 ENSDART00000151771
chpfb
chondroitin polymerizing factor b
chr8_+_54135642 0.40 ENSDART00000170712
brpf1
bromodomain and PHD finger containing, 1
chr2_+_34967210 0.39 ENSDART00000141796
astn1
astrotactin 1
chr16_+_19637384 0.39 ENSDART00000184773
ENSDART00000191895
ENSDART00000182020
ENSDART00000135359
macc1
metastasis associated in colon cancer 1
chr18_+_5917625 0.39 ENSDART00000169100
glg1b
golgi glycoprotein 1b
chr1_+_59328030 0.39 ENSDART00000172464
CABZ01052576.1

chr15_+_17100412 0.39 ENSDART00000154418
relb
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr8_-_22273819 0.39 ENSDART00000121513
nphp4
nephronophthisis 4
chr2_+_19236969 0.38 ENSDART00000163875
ENSDART00000168644
cc2d1b
coiled-coil and C2 domain containing 1B
chr25_-_20666328 0.38 ENSDART00000098076
csk
C-terminal Src kinase
chr7_-_38644560 0.38 ENSDART00000114934
c6ast3
six-cysteine containing astacin protease 3
chr3_-_26183699 0.38 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
si:ch211-11k18.4
chr12_+_18782821 0.37 ENSDART00000152918
mkl1b
megakaryoblastic leukemia (translocation) 1b
chr17_+_15983247 0.37 ENSDART00000154275
clmn
calmin
chr2_-_37280617 0.36 ENSDART00000190458
nadkb
NAD kinase b
chr4_+_72797711 0.36 ENSDART00000190934
ENSDART00000163236
MYRFL
myelin regulatory factor-like

Network of associatons between targets according to the STRING database.

First level regulatory network of figla

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0090008 hypoblast development(GO:0090008)
0.6 3.3 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.3 1.6 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.3 4.7 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.3 2.7 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.2 0.7 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.2 2.3 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 2.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 0.7 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.2 1.8 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.2 0.7 GO:0051660 establishment of centrosome localization(GO:0051660)
0.2 1.0 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.2 1.4 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.2 0.9 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.7 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 1.7 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 0.6 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.1 0.7 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1 0.4 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.6 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.7 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 1.9 GO:0008354 germ cell migration(GO:0008354)
0.1 0.3 GO:1902626 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.6 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 0.6 GO:0061511 centriole elongation(GO:0061511)
0.1 0.7 GO:0021744 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.1 0.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.4 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.6 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.3 GO:0009098 leucine biosynthetic process(GO:0009098)
0.1 0.3 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.3 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.9 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.4 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.1 0.6 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1 1.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 2.8 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.1 0.6 GO:2000725 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.1 0.8 GO:0045453 bone resorption(GO:0045453)
0.1 0.3 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.5 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 2.2 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.4 GO:2000463 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 0.5 GO:0071684 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 1.0 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.6 GO:0061709 reticulophagy(GO:0061709)
0.1 1.9 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 0.3 GO:0032978 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.1 0.8 GO:1900151 regulation of mRNA 3'-end processing(GO:0031440) positive regulation of mRNA 3'-end processing(GO:0031442) regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1 0.3 GO:0090199 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 0.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.7 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.3 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.6 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.4 GO:0021634 optic nerve formation(GO:0021634)
0.0 1.3 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.9 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.6 GO:0061055 myotome development(GO:0061055)
0.0 0.3 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.0 0.2 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.8 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.8 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.3 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.0 1.1 GO:0048599 oocyte development(GO:0048599)
0.0 0.6 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.2 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.3 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.0 0.4 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.3 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.7 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.0 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.5 GO:0031297 replication fork processing(GO:0031297)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.5 GO:0022011 myelination in peripheral nervous system(GO:0022011)
0.0 0.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.5 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.2 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.5 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.3 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.6 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 1.1 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 2.1 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.3 GO:0072160 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
0.0 0.4 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.3 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.6 GO:0021591 ventricular system development(GO:0021591)
0.0 0.1 GO:0070254 mucus secretion(GO:0070254)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 1.0 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.4 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 3.7 GO:0007018 microtubule-based movement(GO:0007018)
0.0 1.1 GO:0032147 activation of protein kinase activity(GO:0032147)
0.0 0.7 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 1.6 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.6 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.0 GO:0015824 proline transport(GO:0015824)
0.0 0.0 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.8 GO:0051607 defense response to virus(GO:0051607)
0.0 0.0 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.7 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.3 GO:0032019 mitochondrial cloud(GO:0032019)
0.3 2.7 GO:0071546 pi-body(GO:0071546)
0.2 1.0 GO:0043073 germ cell nucleus(GO:0043073)
0.2 3.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 2.8 GO:0042555 MCM complex(GO:0042555)
0.2 0.6 GO:0097519 DNA recombinase complex(GO:0097519)
0.1 0.4 GO:0032545 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.1 1.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.1 GO:0030904 retromer complex(GO:0030904)
0.1 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.7 GO:0070652 HAUS complex(GO:0070652)
0.1 0.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 2.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.9 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.7 GO:0005657 replication fork(GO:0005657)
0.0 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 4.6 GO:0043296 apical junction complex(GO:0043296)
0.0 0.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.4 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 2.1 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.1 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.8 GO:0005770 late endosome(GO:0005770)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.3 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.4 3.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.3 1.7 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.3 2.7 GO:0034584 piRNA binding(GO:0034584)
0.3 4.7 GO:0032190 acrosin binding(GO:0032190)
0.2 1.4 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2 1.1 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.2 1.0 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.2 0.6 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 0.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 2.2 GO:0070697 activin receptor binding(GO:0070697)
0.2 0.5 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.2 1.6 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 1.4 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.2 0.9 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 2.5 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.7 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 1.9 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 1.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.8 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 2.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.7 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.3 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.4 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.3 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.7 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.4 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.3 GO:0046592 polyamine oxidase activity(GO:0046592)
0.1 0.3 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 0.2 GO:0042806 fucose binding(GO:0042806)
0.1 0.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.3 GO:0030331 estrogen receptor binding(GO:0030331) retinoic acid receptor binding(GO:0042974)
0.1 0.6 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 1.4 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.2 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.1 1.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.9 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 1.2 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 0.7 GO:0051117 ATPase binding(GO:0051117)
0.0 0.4 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.3 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.6 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.8 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.7 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.7 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.3 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.5 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 2.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.7 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.1 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.2 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.9 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.6 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 2.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.6 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.9 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.9 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.8 GO:0003724 RNA helicase activity(GO:0003724)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 0.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 2.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.3 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.3 PID IGF1 PATHWAY IGF1 pathway
0.0 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.9 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 0.4 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.8 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.2 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling