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PRJNA195909:zebrafish embryo and larva development

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Results for foxa3

Z-value: 1.22

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Transcription factors associated with foxa3

Gene Symbol Gene ID Gene Info
foxa3
ENSDARG00000012788 forkhead box A3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxa3dr11_v1_chr18_-_46354269_463542690.481.9e-01Click!

Activity profile of foxa3 motif

Sorted Z-values of foxa3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_23978978 3.13 ENSDART00000058964
ENSDART00000135084
apoa2
apolipoprotein A-II
chr25_+_7982979 3.06 ENSDART00000171904
ucmab
upper zone of growth plate and cartilage matrix associated b
chr9_+_53725294 2.33 ENSDART00000165991
cnmd
chondromodulin
chr9_+_53725128 2.27 ENSDART00000169062
cnmd
chondromodulin
chr16_+_23913943 2.19 ENSDART00000175404
ENSDART00000129525
apoa4b.1
apolipoprotein A-IV b, tandem duplicate 1
chr5_+_32345187 2.05 ENSDART00000147132
c9
complement component 9
chr5_-_32292965 2.03 ENSDART00000183522
ENSDART00000131983
myhz1.2
myosin, heavy polypeptide 1.2, skeletal muscle
chr3_-_50865079 1.96 ENSDART00000164295
pmp22a
peripheral myelin protein 22a
chr12_-_26064480 1.95 ENSDART00000158215
ENSDART00000171206
ENSDART00000171212
ENSDART00000182956
ENSDART00000186779
ldb3b
LIM domain binding 3b
chr16_+_11724230 1.79 ENSDART00000060266
ceacam1
carcinoembryonic antigen-related cell adhesion molecule 1
chr7_-_33023404 1.70 ENSDART00000052383
cd81a
CD81 molecule a
chr23_+_36653376 1.70 ENSDART00000053189
gpr182
G protein-coupled receptor 182
chr21_-_39081107 1.69 ENSDART00000075935
vtnb
vitronectin b
chr25_-_31423493 1.68 ENSDART00000027661
myod1
myogenic differentiation 1
chr16_-_21785261 1.56 ENSDART00000078858
si:ch73-86n18.1
si:ch73-86n18.1
chr2_+_5563077 1.53 ENSDART00000111220
mb21d2
Mab-21 domain containing 2
chr19_-_28789404 1.50 ENSDART00000191453
ENSDART00000026992
sox4a
SRY (sex determining region Y)-box 4a
chr5_+_49744713 1.49 ENSDART00000133384
nr2f1a
nuclear receptor subfamily 2, group F, member 1a
chr18_+_17611627 1.49 ENSDART00000046891
cetp
cholesteryl ester transfer protein, plasma
chr1_-_44940830 1.47 ENSDART00000097500
ENSDART00000134464
ENSDART00000137216
tmem176
transmembrane protein 176
chr5_-_20194876 1.45 ENSDART00000122587
dao.1
D-amino-acid oxidase, tandem duplicate 1
chr8_+_26818446 1.44 ENSDART00000134987
ENSDART00000138835
si:ch211-156j16.1
si:ch211-156j16.1
chr6_+_24817852 1.44 ENSDART00000165609
barhl2
BarH-like homeobox 2
chr7_-_8417315 1.37 ENSDART00000173046
jac1
jacalin 1
chr20_-_9980318 1.29 ENSDART00000080664
ACTC1
zgc:86709
chr7_-_27033080 1.28 ENSDART00000173516
nucb2a
nucleobindin 2a
chr1_+_36651059 1.27 ENSDART00000187475
ednraa
endothelin receptor type Aa
chr16_+_23961276 1.18 ENSDART00000192754
apoeb
apolipoprotein Eb
chr2_+_38161318 1.17 ENSDART00000044264
mmp14b
matrix metallopeptidase 14b (membrane-inserted)
chr8_-_16697912 1.14 ENSDART00000076542
rpe65b
retinal pigment epithelium-specific protein 65b
chr4_-_9722568 1.14 ENSDART00000067190
tspan9b
tetraspanin 9b
chr16_+_20904754 1.12 ENSDART00000006043
hoxa11b
homeobox A11b
chr3_+_23743139 1.12 ENSDART00000187409
hoxb3a
homeobox B3a
chr15_-_26552393 1.11 ENSDART00000150152
serpinf2b
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr6_-_8736766 1.10 ENSDART00000143956
cavin2b
caveolae associated protein 2b
chr20_-_10120442 1.10 ENSDART00000144970
meis2b
Meis homeobox 2b
chr17_-_42218652 1.08 ENSDART00000081396
ENSDART00000190007
nkx2.2a
NK2 homeobox 2a
chr20_+_52546186 1.06 ENSDART00000110777
ENSDART00000153377
ENSDART00000153013
ENSDART00000042704
eef1db
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr8_+_25902170 1.05 ENSDART00000193130
rhoab
ras homolog gene family, member Ab
chr15_+_36941490 1.04 ENSDART00000172664
kirrel3l
kirre like nephrin family adhesion molecule 3, like
chr7_-_26844064 1.04 ENSDART00000162241
si:ch211-107p11.3
si:ch211-107p11.3
chr20_+_15015557 1.04 ENSDART00000039345
myoc
myocilin
chr5_+_52039067 1.03 ENSDART00000143276
setbp1
SET binding protein 1
chr15_+_7176182 1.03 ENSDART00000101578
her8.2
hairy-related 8.2
chr21_+_30549512 1.03 ENSDART00000132831
rab38c
RAB38c, member of RAS oncogene family
chr16_-_24044664 1.01 ENSDART00000136982
bcam
basal cell adhesion molecule (Lutheran blood group)
chr7_-_58729894 0.99 ENSDART00000149347
chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr9_+_51265283 0.95 ENSDART00000137426
gcgb
glucagon b
chr4_-_16334362 0.94 ENSDART00000101461
epyc
epiphycan
chr19_-_47526737 0.92 ENSDART00000186636
scg5
secretogranin V
chr5_-_16351306 0.91 ENSDART00000168643
CABZ01088700.1

chr1_+_26667872 0.91 ENSDART00000152803
ENSDART00000152144
ENSDART00000152785
ENSDART00000152393
hemgn
hemogen
chr2_+_30916188 0.91 ENSDART00000137012
myom1a
myomesin 1a (skelemin)
chr16_-_35952789 0.90 ENSDART00000180118
eva1ba
eva-1 homolog Ba (C. elegans)
chr14_+_20893065 0.90 ENSDART00000079452
lygl1
lysozyme g-like 1
chr3_+_32492467 0.89 ENSDART00000151329
trpm4a
transient receptor potential cation channel, subfamily M, member 4a
chr9_+_52411530 0.89 ENSDART00000163684
nme8
NME/NM23 family member 8
chr1_+_36612660 0.89 ENSDART00000190784
ednraa
endothelin receptor type Aa
chr8_+_17184602 0.88 ENSDART00000050228
ENSDART00000140531
dimt1l
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
chr21_-_17296789 0.88 ENSDART00000192180
gfi1b
growth factor independent 1B transcription repressor
chr14_+_7932973 0.88 ENSDART00000109941
cxxc5b
CXXC finger protein 5b
chr6_-_55997350 0.85 ENSDART00000011652
eya2
EYA transcriptional coactivator and phosphatase 2
chr8_+_49570884 0.82 ENSDART00000182117
ENSDART00000108613
rasef
RAS and EF-hand domain containing
chr1_+_44941031 0.82 ENSDART00000141145
si:dkey-9i23.16
si:dkey-9i23.16
chr12_+_26467847 0.82 ENSDART00000022495
ndel1a
nudE neurodevelopment protein 1-like 1a
chr4_-_13921185 0.82 ENSDART00000143202
ENSDART00000080334
yaf2
YY1 associated factor 2
chr5_-_28029558 0.81 ENSDART00000078649
abcb9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr13_+_22480857 0.80 ENSDART00000078721
ENSDART00000044719
ENSDART00000130957
ENSDART00000078757
ENSDART00000130424
ENSDART00000078747
ldb3a
LIM domain binding 3a
chr2_+_16160906 0.80 ENSDART00000135783
selenoj
selenoprotein J
chr20_-_29474859 0.80 ENSDART00000152906
ENSDART00000045249
scg5
secretogranin V
chr7_-_41554047 0.80 ENSDART00000174144
plxdc2
plexin domain containing 2
chr12_-_2993095 0.79 ENSDART00000152316
si:dkey-202c14.3
si:dkey-202c14.3
chr8_-_14184423 0.79 ENSDART00000063817
ndufb11
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11
chr14_-_29799993 0.79 ENSDART00000133775
ENSDART00000005568
pdlim3b
PDZ and LIM domain 3b
chr8_-_34065573 0.79 ENSDART00000186946
pbx3b
pre-B-cell leukemia homeobox 3b
chr5_-_24000211 0.79 ENSDART00000188865
map7d2a
MAP7 domain containing 2a
chr7_-_58098814 0.78 ENSDART00000147287
ENSDART00000043984
ank2b
ankyrin 2b, neuronal
chr18_-_16795262 0.77 ENSDART00000048722
ampd3b
adenosine monophosphate deaminase 3b
chr3_-_28258462 0.77 ENSDART00000191573
rbfox1
RNA binding fox-1 homolog 1
chr16_-_54455573 0.77 ENSDART00000075275
pklr
pyruvate kinase L/R
chr20_-_29475172 0.76 ENSDART00000183164
scg5
secretogranin V
chr1_-_22834824 0.76 ENSDART00000043556
ldb2b
LIM domain binding 2b
chr14_-_25985698 0.76 ENSDART00000172909
ENSDART00000123053
atox1
antioxidant 1 copper chaperone
chr16_+_31804590 0.76 ENSDART00000167321
wnt4b
wingless-type MMTV integration site family, member 4b
chr14_-_25040359 0.76 ENSDART00000162556
TMEM216
si:rp71-1d10.5
chr18_-_14777092 0.74 ENSDART00000144660
mtss1la
metastasis suppressor 1-like a
chr15_-_26552652 0.73 ENSDART00000152336
serpinf2b
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr2_-_38035235 0.72 ENSDART00000075904
cbln5
cerebellin 5
chr16_-_8280885 0.72 ENSDART00000129068
entpd3
ectonucleoside triphosphate diphosphohydrolase 3
chr8_-_27858458 0.71 ENSDART00000132632
ENSDART00000136562
cttnbp2nlb
CTTNBP2 N-terminal like b
chr7_+_15872357 0.71 ENSDART00000165757
pax6b
paired box 6b
chr2_-_30200206 0.71 ENSDART00000130142
ube2w
ubiquitin-conjugating enzyme E2W (putative)
chr13_-_40726865 0.70 ENSDART00000099847
st3gal7
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr14_-_36799280 0.70 ENSDART00000168615
rnf130
ring finger protein 130
chr1_+_25801648 0.69 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr13_+_42544009 0.68 ENSDART00000145409
si:dkey-221j11.3
si:dkey-221j11.3
chr5_+_34622320 0.68 ENSDART00000141338
enc1
ectodermal-neural cortex 1
chr9_+_4429593 0.68 ENSDART00000184855
FP015810.1

chr6_-_39275793 0.68 ENSDART00000180477
ENSDART00000148531
arhgef25b
Rho guanine nucleotide exchange factor (GEF) 25b
chr10_-_15128771 0.67 ENSDART00000101261
spp1
secreted phosphoprotein 1
chr22_-_21176269 0.67 ENSDART00000112839
rex1bd
required for excision 1-B domain containing
chr24_+_20575259 0.67 ENSDART00000010488
klhl40b
kelch-like family member 40b
chr15_+_24644016 0.66 ENSDART00000043292
smtnl
smoothelin, like
chr17_-_42213285 0.66 ENSDART00000140549
nkx2.2a
NK2 homeobox 2a
chr23_+_42813415 0.66 ENSDART00000055577
myl9a
myosin, light chain 9a, regulatory
chr8_-_16712111 0.65 ENSDART00000184147
ENSDART00000180419
ENSDART00000076600
rpe65c
retinal pigment epithelium-specific protein 65c
chr21_-_22951604 0.64 ENSDART00000083449
ENSDART00000180129
dub
duboraya
chr9_-_21912227 0.63 ENSDART00000145576
lmo7a
LIM domain 7a
chr15_-_28247583 0.63 ENSDART00000112967
rilp
Rab interacting lysosomal protein
chr7_+_20512419 0.62 ENSDART00000173907
si:dkey-19b23.14
si:dkey-19b23.14
chr24_+_9475809 0.62 ENSDART00000132688
si:ch211-285f17.1
si:ch211-285f17.1
chr1_+_26071869 0.62 ENSDART00000059264
mxd4
MAX dimerization protein 4
chr1_+_37391716 0.61 ENSDART00000191986
sparcl1
SPARC-like 1
chr9_+_44431174 0.60 ENSDART00000149726
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr9_-_23253870 0.59 ENSDART00000143657
ENSDART00000169911
acmsd
aminocarboxymuconate semialdehyde decarboxylase
chr22_-_14128716 0.59 ENSDART00000140323
si:ch211-246m6.4
si:ch211-246m6.4
chr16_+_43152727 0.59 ENSDART00000125590
ENSDART00000154493
adam22
ADAM metallopeptidase domain 22
chr1_+_11107688 0.58 ENSDART00000109858
knstrn
kinetochore-localized astrin/SPAG5 binding protein
chr13_-_11667661 0.58 ENSDART00000102411
dctn1b
dynactin 1b
chr22_-_24285432 0.58 ENSDART00000164083
si:ch211-117l17.4
si:ch211-117l17.4
chr11_-_36350876 0.57 ENSDART00000146495
ENSDART00000020655
psma5
proteasome subunit alpha 5
chr10_+_31951338 0.57 ENSDART00000019416
lhfpl6
LHFPL tetraspan subfamily member 6
chr25_-_13188678 0.57 ENSDART00000125754
si:ch211-147m6.1
si:ch211-147m6.1
chr14_-_33894915 0.56 ENSDART00000143290
urp1
urotensin-related peptide 1
chr6_-_56111829 0.56 ENSDART00000154397
gcnt7
glucosaminyl (N-acetyl) transferase family member 7
chr19_+_2275019 0.56 ENSDART00000136138
itgb8
integrin, beta 8
chr4_-_14926637 0.56 ENSDART00000110199
prdm4
PR domain containing 4
chr3_+_12484008 0.55 ENSDART00000182229
vasnb
vasorin b
chr18_-_14337450 0.54 ENSDART00000061435
hsbp1b
heat shock factor binding protein 1b
chr1_-_54622227 0.54 ENSDART00000049010
tekt4
tektin 4
chr22_-_36856405 0.54 ENSDART00000029588
kng1
kininogen 1
chr11_-_36350421 0.53 ENSDART00000141477
psma5
proteasome subunit alpha 5
chr1_-_10806625 0.53 ENSDART00000139749
si:ch73-222h13.1
si:ch73-222h13.1
chr4_-_1824836 0.53 ENSDART00000111858
mrpl42
mitochondrial ribosomal protein L42
chr7_+_48705227 0.52 ENSDART00000174034
AL929208.1

chr9_+_44430974 0.51 ENSDART00000056846
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr17_-_28707898 0.50 ENSDART00000135752
ENSDART00000061853
ap4s1
adaptor-related protein complex 4, sigma 1 subunit
chr20_+_51104367 0.50 ENSDART00000073981
eif2s1b
eukaryotic translation initiation factor 2, subunit 1 alpha b
chr11_-_30634286 0.50 ENSDART00000191019
zgc:153665
zgc:153665
chr8_+_24747865 0.49 ENSDART00000078656
slc16a4
solute carrier family 16, member 4
chr15_+_29123031 0.48 ENSDART00000133988
ENSDART00000060030
zgc:101731
zgc:101731
chr5_+_22970617 0.48 ENSDART00000192859
hmgn7
high mobility group nucleosomal binding domain 7
chr20_-_42203629 0.48 ENSDART00000074959
slc35f1
solute carrier family 35, member F1
chr15_+_36187434 0.48 ENSDART00000181536
ENSDART00000099501
ENSDART00000154432
masp1
mannan-binding lectin serine peptidase 1
chr14_-_6931889 0.48 ENSDART00000166439
si:ch211-266k2.1
si:ch211-266k2.1
chr18_+_19975787 0.48 ENSDART00000138103
skor1b
SKI family transcriptional corepressor 1b
chr21_-_25774605 0.47 ENSDART00000002128
CLDN4 (1 of many)
zgc:112437
chr20_+_38525567 0.47 ENSDART00000147787
znf512
zinc finger protein 512
chr5_+_26913120 0.47 ENSDART00000126609
tbx3b
T-box 3b
chr18_-_40884087 0.47 ENSDART00000059194
snrpd2
small nuclear ribonucleoprotein D2 polypeptide
chr4_+_1600034 0.46 ENSDART00000146779
slc38a2
solute carrier family 38, member 2
chr4_+_14926948 0.46 ENSDART00000019647
psmc2
proteasome 26S subunit, ATPase 2
chr11_-_31172276 0.46 ENSDART00000171520
si:dkey-238i5.3
si:dkey-238i5.3
chr14_-_2221877 0.45 ENSDART00000106704
pcdh2ab1
protocadherin 2 alpha b 1
chr19_-_47527093 0.45 ENSDART00000171379
ENSDART00000171140
ENSDART00000114886
scg5
secretogranin V
chr1_+_54865552 0.44 ENSDART00000145381
si:ch211-196h16.5
si:ch211-196h16.5
chr14_-_17588345 0.44 ENSDART00000143486
selenot2
selenoprotein T, 2
chr4_-_149334 0.44 ENSDART00000163280
tbk1
TANK-binding kinase 1
chr20_+_30445971 0.44 ENSDART00000153150
myt1la
myelin transcription factor 1-like, a
chr7_+_26138240 0.42 ENSDART00000193750
ENSDART00000184942
nat16
N-acetyltransferase 16
chr9_-_34396264 0.42 ENSDART00000045754
grtp1b
growth hormone regulated TBC protein 1b
chr18_+_20566817 0.42 ENSDART00000100716
bida
BH3 interacting domain death agonist
chr1_+_1805294 0.42 ENSDART00000103850
atp1a1a.3
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 3
chr3_+_5575313 0.42 ENSDART00000134693
ENSDART00000101807
si:ch211-106h11.3
si:ch211-106h11.3
chr22_-_18179214 0.41 ENSDART00000129576
si:ch211-125m10.6
si:ch211-125m10.6
chr13_-_47403154 0.41 ENSDART00000114318
bcl2l11
BCL2 like 11
chr14_-_4120636 0.41 ENSDART00000059230
irf2
interferon regulatory factor 2
chr23_+_45584223 0.41 ENSDART00000149367
si:ch73-290k24.5
si:ch73-290k24.5
chr21_-_26490186 0.40 ENSDART00000009889
zgc:110540
zgc:110540
chr1_-_39909985 0.40 ENSDART00000181673
stox2a
storkhead box 2a
chr17_+_51262556 0.40 ENSDART00000186748
ENSDART00000181606
ENSDART00000063738
ENSDART00000189066
eipr1
EARP complex and GARP complex interacting protein 1
chr24_-_31306724 0.40 ENSDART00000165399
acp5b
acid phosphatase 5b, tartrate resistant
chr20_-_39273505 0.40 ENSDART00000153114
clu
clusterin
chr24_-_21172122 0.39 ENSDART00000154259
atp6v1ab
ATPase H+ transporting V1 subunit Ab
chr10_-_10607118 0.39 ENSDART00000101089
dbh
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr3_+_50310684 0.38 ENSDART00000112152
gas7a
growth arrest-specific 7a
chr23_+_2778813 0.38 ENSDART00000142621
top1
DNA topoisomerase I
chr24_+_11381400 0.38 ENSDART00000058703
ackr4b
atypical chemokine receptor 4b
chr2_+_20539402 0.38 ENSDART00000129585
si:ch73-14h1.2
si:ch73-14h1.2
chr4_-_74466703 0.38 ENSDART00000174032
ENSDART00000189417
LO018124.1

chr25_+_19149241 0.38 ENSDART00000184982
ENSDART00000067324
mfge8b
milk fat globule-EGF factor 8 protein b
chr21_-_25295087 0.38 ENSDART00000087910
ENSDART00000147860
st14b
suppression of tumorigenicity 14 (colon carcinoma) b
chr21_+_17768174 0.38 ENSDART00000141380
rxraa
retinoid X receptor, alpha a
chr2_+_58008980 0.38 ENSDART00000171264
si:ch211-155e24.3
si:ch211-155e24.3
chr23_-_21515182 0.38 ENSDART00000142000
rnf207b
ring finger protein 207b
chr10_+_10728870 0.37 ENSDART00000109282
swi5
SWI5 homologous recombination repair protein
chr25_+_24616717 0.37 ENSDART00000089113
abtb2b
ankyrin repeat and BTB (POZ) domain containing 2b
chr24_-_26485098 0.37 ENSDART00000135496
ENSDART00000009609
ENSDART00000133782
ENSDART00000141029
ENSDART00000113739
eif5a
eukaryotic translation initiation factor 5A
chr9_+_44430705 0.37 ENSDART00000190696
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr11_-_29563437 0.36 ENSDART00000163958
arhgef10la
Rho guanine nucleotide exchange factor (GEF) 10-like a
chr16_-_50203058 0.36 ENSDART00000154570
vsig10l
V-set and immunoglobulin domain containing 10 like
chr21_-_1625976 0.36 ENSDART00000066621
vmo1b
vitelline membrane outer layer 1 homolog b
chr13_+_7292061 0.35 ENSDART00000179504
CABZ01072077.1
Danio rerio neuroblast differentiation-associated protein AHNAK-like (LOC795051), mRNA.
chr19_+_1873059 0.35 ENSDART00000145246
snrpd1
small nuclear ribonucleoprotein D1 polypeptide
chr1_+_2190714 0.35 ENSDART00000132126
mbnl2
muscleblind-like splicing regulator 2
chr15_-_29586747 0.35 ENSDART00000076749
samsn1a
SAM domain, SH3 domain and nuclear localisation signals 1a
chr17_-_53439866 0.35 ENSDART00000154826
mycbp
c-myc binding protein
chr11_+_691734 0.34 ENSDART00000191463
timp4.1
TIMP metallopeptidase inhibitor 4, tandem duplicate 1
chr20_-_14925281 0.34 ENSDART00000152641
dnm3a
dynamin 3a
chr7_-_20836625 0.34 ENSDART00000192566
cldn15a
claudin 15a

Network of associatons between targets according to the STRING database.

First level regulatory network of foxa3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.7 2.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.6 1.7 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.6 1.7 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.5 1.5 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.4 1.8 GO:0016108 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.4 1.2 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.4 1.4 GO:0009080 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.4 2.2 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.3 0.9 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.3 0.9 GO:0002369 T cell cytokine production(GO:0002369)
0.2 0.7 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.2 0.6 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.2 3.1 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.2 2.6 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.2 0.7 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.2 0.8 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 1.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.8 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 1.2 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.4 GO:0006589 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.1 1.3 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1 0.4 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.1 0.6 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.2 GO:0045778 positive regulation of bone mineralization(GO:0030501) positive regulation of ossification(GO:0045778) positive regulation of biomineral tissue development(GO:0070169)
0.1 0.4 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 0.7 GO:0090104 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
0.1 0.6 GO:0046874 quinolinate biosynthetic process(GO:0019805) quinolinate metabolic process(GO:0046874)
0.1 0.3 GO:0010359 regulation of anion channel activity(GO:0010359)
0.1 0.8 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.1 0.9 GO:2001239 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.5 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 0.5 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.8 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.2 GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.1 0.1 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 0.4 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 2.9 GO:0046883 regulation of hormone secretion(GO:0046883)
0.1 1.0 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.1 0.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.8 GO:0032264 IMP salvage(GO:0032264)
0.1 1.5 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.9 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.5 GO:0006868 glutamine transport(GO:0006868)
0.0 0.7 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 1.0 GO:0039022 pronephric duct development(GO:0039022)
0.0 0.8 GO:0032438 melanosome organization(GO:0032438)
0.0 0.5 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.3 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.1 GO:0019323 pentose catabolic process(GO:0019323)
0.0 0.7 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.4 GO:0045453 bone resorption(GO:0045453)
0.0 2.9 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0 1.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 0.3 GO:0009914 hormone transport(GO:0009914)
0.0 0.4 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.4 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.8 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 0.6 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.3 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 1.3 GO:0006414 translational elongation(GO:0006414)
0.0 0.2 GO:0030262 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.4 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.4 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.2 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.6 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.2 GO:0048942 myelination of lateral line nerve axons(GO:0048897) posterior lateral line nerve glial cell differentiation(GO:0048931) myelination of posterior lateral line nerve axons(GO:0048932) lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048938) posterior lateral line nerve glial cell development(GO:0048941) posterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048942)
0.0 0.1 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 0.6 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.3 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.1 GO:0090342 regulation of cell aging(GO:0090342)
0.0 0.5 GO:0014029 neural crest formation(GO:0014029)
0.0 1.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.8 GO:0021854 limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.0 0.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.3 GO:0006301 postreplication repair(GO:0006301)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.2 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.8 GO:0006096 glycolytic process(GO:0006096)
0.0 0.0 GO:0072673 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.9 GO:0060216 definitive hemopoiesis(GO:0060216)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0044218 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.3 1.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 1.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 0.5 GO:0043614 multi-eIF complex(GO:0043614)
0.2 0.8 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 1.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 3.5 GO:0031941 filamentous actin(GO:0031941)
0.1 0.2 GO:0005775 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.1 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.6 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.6 GO:0031672 A band(GO:0031672)
0.1 0.4 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.8 GO:0030315 T-tubule(GO:0030315)
0.0 0.3 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.4 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.0 0.5 GO:0005682 U5 snRNP(GO:0005682)
0.0 2.7 GO:0030141 secretory granule(GO:0030141)
0.0 0.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 1.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.0 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.1 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 1.3 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 5.7 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.4 1.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.4 1.4 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.3 2.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.3 0.8 GO:0046978 TAP1 binding(GO:0046978)
0.3 0.8 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 1.7 GO:0070888 E-box binding(GO:0070888)
0.2 0.7 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.2 0.9 GO:0003796 lysozyme activity(GO:0003796)
0.2 0.9 GO:0031769 glucagon receptor binding(GO:0031769)
0.2 3.5 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.2 0.9 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 0.8 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.4 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 0.8 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.2 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.1 0.8 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 1.5 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 1.1 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.4 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 1.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 1.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.5 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.9 GO:0099604 ligand-gated calcium channel activity(GO:0099604)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.0 0.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.5 GO:0043022 ribosome binding(GO:0043022)
0.0 1.6 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 PID IGF1 PATHWAY IGF1 pathway
0.0 0.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 0.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 0.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.1 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.8 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling