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PRJNA195909:zebrafish embryo and larva development

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Results for foxa_foxa1_foxa2

Z-value: 1.55

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Transcription factors associated with foxa_foxa1_foxa2

Gene Symbol Gene ID Gene Info
foxa
ENSDARG00000087094 forkhead box A sequence
foxa
ENSDARG00000110743 forkhead box A sequence
foxa
ENSDARG00000115019 forkhead box A sequence
foxa1
ENSDARG00000102138 forkhead box A1
foxa2
ENSDARG00000003411 forkhead box A2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxa1dr11_v1_chr17_+_10318071_103180710.933.2e-04Click!
foxadr11_v1_chr14_-_33981544_33981544-0.881.8e-03Click!
foxa2dr11_v1_chr17_-_42568498_425684980.609.0e-02Click!

Activity profile of foxa_foxa1_foxa2 motif

Sorted Z-values of foxa_foxa1_foxa2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_31616412 4.84 ENSDART00000124439
cpn1
carboxypeptidase N, polypeptide 1
chr9_+_53725294 3.66 ENSDART00000165991
cnmd
chondromodulin
chr5_+_49744713 3.64 ENSDART00000133384
nr2f1a
nuclear receptor subfamily 2, group F, member 1a
chr9_+_53725128 3.55 ENSDART00000169062
cnmd
chondromodulin
chr16_-_21785261 3.20 ENSDART00000078858
si:ch73-86n18.1
si:ch73-86n18.1
chr3_-_50863370 3.00 ENSDART00000169771
ENSDART00000165083
pmp22a
peripheral myelin protein 22a
chr16_+_23978978 2.91 ENSDART00000058964
ENSDART00000135084
apoa2
apolipoprotein A-II
chr15_-_18138607 2.85 ENSDART00000176690
CR385077.1

chr4_+_17417111 2.80 ENSDART00000056005
ascl1a
achaete-scute family bHLH transcription factor 1a
chr6_+_24817852 2.57 ENSDART00000165609
barhl2
BarH-like homeobox 2
chr12_-_4781801 2.42 ENSDART00000167490
ENSDART00000121718
mapta
microtubule-associated protein tau a
chr15_+_7176182 2.30 ENSDART00000101578
her8.2
hairy-related 8.2
chr24_-_38288883 2.26 ENSDART00000169988
zgc:91999
zgc:91999
chr6_-_32703317 2.18 ENSDART00000064833
mafaa
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa
chr2_+_38161318 2.09 ENSDART00000044264
mmp14b
matrix metallopeptidase 14b (membrane-inserted)
chr12_-_31103906 1.92 ENSDART00000189099
ENSDART00000121527
ENSDART00000185635
ENSDART00000183754
tcf7l2
transcription factor 7 like 2
chr25_-_15049694 1.89 ENSDART00000162485
ENSDART00000164384
ENSDART00000165632
ENSDART00000159490
pax6a
paired box 6a
chr23_+_28770225 1.83 ENSDART00000132179
ENSDART00000142273
masp2
mannan-binding lectin serine peptidase 2
chr20_+_26881600 1.78 ENSDART00000174799
serpinb1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr16_-_29277164 1.75 ENSDART00000058870
rhbg
Rh family, B glycoprotein (gene/pseudogene)
chr20_-_20533865 1.69 ENSDART00000125039
six6b
SIX homeobox 6b
chr6_+_14949950 1.68 ENSDART00000149202
ENSDART00000149949
pou3f3b
POU class 3 homeobox 3b
chr18_-_14777092 1.67 ENSDART00000144660
mtss1la
metastasis suppressor 1-like a
chr3_-_50865079 1.66 ENSDART00000164295
pmp22a
peripheral myelin protein 22a
chr19_-_28789404 1.61 ENSDART00000191453
ENSDART00000026992
sox4a
SRY (sex determining region Y)-box 4a
chr16_-_54455573 1.57 ENSDART00000075275
pklr
pyruvate kinase L/R
chr4_-_16353733 1.56 ENSDART00000186785
lum
lumican
chr13_-_31647323 1.56 ENSDART00000135381
six4a
SIX homeobox 4a
chr23_+_36115541 1.55 ENSDART00000130090
hoxc6a
homeobox C6a
chr14_-_34044369 1.55 ENSDART00000149396
ENSDART00000123607
ENSDART00000190746
cyfip2
cytoplasmic FMR1 interacting protein 2
chr12_-_31103187 1.54 ENSDART00000005562
ENSDART00000031408
ENSDART00000125046
ENSDART00000009237
ENSDART00000122972
ENSDART00000153068
tcf7l2
transcription factor 7 like 2
chr15_+_36941490 1.53 ENSDART00000172664
kirrel3l
kirre like nephrin family adhesion molecule 3, like
chr2_+_16780643 1.52 ENSDART00000125647
ENSDART00000108611
ENSDART00000181245
ENSDART00000163194
tfa
transferrin-a
chr16_+_11724230 1.50 ENSDART00000060266
ceacam1
carcinoembryonic antigen-related cell adhesion molecule 1
chr4_+_7677318 1.49 ENSDART00000149218
elk3
ELK3, ETS-domain protein
chr17_+_15297398 1.44 ENSDART00000156574
si:ch211-270g19.5
si:ch211-270g19.5
chr20_-_19365875 1.44 ENSDART00000063703
ENSDART00000187707
ENSDART00000161065
si:dkey-71h2.2
si:dkey-71h2.2
chr21_-_36972127 1.42 ENSDART00000100310
dbn1
drebrin 1
chr9_+_52411530 1.42 ENSDART00000163684
nme8
NME/NM23 family member 8
chr3_-_43356082 1.41 ENSDART00000171213
uncx
UNC homeobox
chr4_-_17725008 1.41 ENSDART00000016658
chpt1
choline phosphotransferase 1
chr24_+_20575259 1.40 ENSDART00000010488
klhl40b
kelch-like family member 40b
chr16_-_35952789 1.40 ENSDART00000180118
eva1ba
eva-1 homolog Ba (C. elegans)
chr21_+_13861589 1.39 ENSDART00000015629
ENSDART00000171306
stxbp1a
syntaxin binding protein 1a
chr8_+_25902170 1.38 ENSDART00000193130
rhoab
ras homolog gene family, member Ab
chr6_-_8736766 1.37 ENSDART00000143956
cavin2b
caveolae associated protein 2b
chr14_-_36799280 1.36 ENSDART00000168615
rnf130
ring finger protein 130
chr2_+_16781015 1.34 ENSDART00000155147
ENSDART00000003845
tfa
transferrin-a
chr9_+_51265283 1.31 ENSDART00000137426
gcgb
glucagon b
chr18_-_16795262 1.30 ENSDART00000048722
ampd3b
adenosine monophosphate deaminase 3b
chr23_+_36063599 1.29 ENSDART00000103147
hoxc12a
homeobox C12a
chr17_-_42213285 1.28 ENSDART00000140549
nkx2.2a
NK2 homeobox 2a
chr8_-_14184423 1.28 ENSDART00000063817
ndufb11
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11
chr14_+_33722950 1.26 ENSDART00000075312
apln
apelin
chr18_-_18543358 1.25 ENSDART00000126460
il34
interleukin 34
chr7_-_58729894 1.24 ENSDART00000149347
chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr14_+_16937997 1.22 ENSDART00000163013
ENSDART00000167856
limch1b
LIM and calponin homology domains 1b
chr19_-_35733401 1.21 ENSDART00000066712
trappc3
trafficking protein particle complex 3
chr15_+_24644016 1.21 ENSDART00000043292
smtnl
smoothelin, like
chr23_-_30787932 1.21 ENSDART00000135771
myt1a
myelin transcription factor 1a
chr10_+_39084354 1.21 ENSDART00000158245
si:ch73-1a9.3
si:ch73-1a9.3
chr22_+_3914318 1.18 ENSDART00000188774
ENSDART00000082034
FO904903.1
Danio rerio major histocompatibility complex class I ULA (mhc1ula), mRNA.
chr23_-_33750135 1.18 ENSDART00000187641
bin2a
bridging integrator 2a
chr7_-_58098814 1.17 ENSDART00000147287
ENSDART00000043984
ank2b
ankyrin 2b, neuronal
chr7_+_33314925 1.16 ENSDART00000148590
coro2ba
coronin, actin binding protein, 2Ba
chr16_-_43025885 1.15 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
si:dkey-7j14.5
chr22_-_36856405 1.14 ENSDART00000029588
kng1
kininogen 1
chr10_-_17232372 1.12 ENSDART00000135679
rab36
RAB36, member RAS oncogene family
chr20_+_6590220 1.12 ENSDART00000136567
tns3.2
tensin 3, tandem duplicate 2
chr1_-_25177086 1.11 ENSDART00000144711
ENSDART00000177225
tmem154
transmembrane protein 154
chr7_+_48805534 1.10 ENSDART00000145375
ENSDART00000148744
cpt1aa
carnitine palmitoyltransferase 1Aa (liver)
chr19_+_16032383 1.10 ENSDART00000046530
rab42a
RAB42, member RAS oncogene family a
chr6_+_40775800 1.08 ENSDART00000085090
si:ch211-157b11.8
si:ch211-157b11.8
chr11_-_12051805 1.07 ENSDART00000110117
ENSDART00000182744
socs7
suppressor of cytokine signaling 7
chr22_-_3914162 1.06 ENSDART00000187174
ENSDART00000190612
ENSDART00000187928
ENSDART00000057224
ENSDART00000184758
mhc1uma
major histocompatibility complex class I UMA
chr7_-_72605673 1.05 ENSDART00000123887
MAPK8IP1 (1 of many)
mitogen-activated protein kinase 8 interacting protein 1
chr14_-_33894915 1.04 ENSDART00000143290
urp1
urotensin-related peptide 1
chr8_+_49570884 1.03 ENSDART00000182117
ENSDART00000108613
rasef
RAS and EF-hand domain containing
chr10_+_6318227 1.03 ENSDART00000170872
ENSDART00000162428
ENSDART00000158994
tpm2
tropomyosin 2 (beta)
chr1_+_36612660 1.02 ENSDART00000190784
ednraa
endothelin receptor type Aa
chr17_-_42218652 1.01 ENSDART00000081396
ENSDART00000190007
nkx2.2a
NK2 homeobox 2a
chr25_-_35360096 1.01 ENSDART00000154053
ENSDART00000171917
si:ch73-147o17.1
si:ch73-147o17.1
chr20_+_25225112 1.01 ENSDART00000153088
ENSDART00000127291
ENSDART00000130494
moxd1
monooxygenase, DBH-like 1
chr14_-_29799993 1.00 ENSDART00000133775
ENSDART00000005568
pdlim3b
PDZ and LIM domain 3b
chr4_+_8797197 0.98 ENSDART00000158671
sult4a1
sulfotransferase family 4A, member 1
chr19_+_2275019 0.98 ENSDART00000136138
itgb8
integrin, beta 8
chr16_-_13595027 0.97 ENSDART00000060004
ntd5
ntl-dependent gene 5
chr16_+_23431189 0.96 ENSDART00000004679
icn
ictacalcin
chr23_-_33750307 0.95 ENSDART00000162772
bin2a
bridging integrator 2a
chr22_-_14128716 0.95 ENSDART00000140323
si:ch211-246m6.4
si:ch211-246m6.4
chr13_-_34781984 0.95 ENSDART00000172138
ism1
isthmin 1
chr2_-_30200206 0.94 ENSDART00000130142
ube2w
ubiquitin-conjugating enzyme E2W (putative)
chr1_-_22834824 0.94 ENSDART00000043556
ldb2b
LIM domain binding 2b
chr24_-_31306724 0.93 ENSDART00000165399
acp5b
acid phosphatase 5b, tartrate resistant
chr10_+_31951338 0.93 ENSDART00000019416
lhfpl6
LHFPL tetraspan subfamily member 6
chr20_+_52546186 0.93 ENSDART00000110777
ENSDART00000153377
ENSDART00000153013
ENSDART00000042704
eef1db
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr1_+_25801648 0.92 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr15_-_28247583 0.91 ENSDART00000112967
rilp
Rab interacting lysosomal protein
chr21_+_11503212 0.90 ENSDART00000146701
si:dkey-184p9.7
si:dkey-184p9.7
chr8_+_26818446 0.90 ENSDART00000134987
ENSDART00000138835
si:ch211-156j16.1
si:ch211-156j16.1
chr18_+_26899316 0.90 ENSDART00000050230
tspan3a
tetraspanin 3a
chr20_-_36809059 0.90 ENSDART00000062925
slc25a27
solute carrier family 25, member 27
chr18_-_40901707 0.89 ENSDART00000139352
foxg1c
forkhead box G1c
chr13_-_21701323 0.88 ENSDART00000164112
si:dkey-191g9.7
si:dkey-191g9.7
chr25_-_13188678 0.88 ENSDART00000125754
si:ch211-147m6.1
si:ch211-147m6.1
chr15_-_41245962 0.88 ENSDART00000155359
smco4
single-pass membrane protein with coiled-coil domains 4
chr1_+_41849152 0.85 ENSDART00000053685
smox
spermine oxidase
chr9_-_19161982 0.85 ENSDART00000081878
pou1f1
POU class 1 homeobox 1
chr21_-_22951604 0.85 ENSDART00000083449
ENSDART00000180129
dub
duboraya
chr15_-_30816370 0.84 ENSDART00000142982
ENSDART00000050649
ENSDART00000136901
ENSDART00000100194
msi2b
musashi RNA-binding protein 2b
chr14_-_26177156 0.83 ENSDART00000014149
fat2
FAT atypical cadherin 2
chr10_+_39091716 0.83 ENSDART00000193072
si:ch73-1a9.4
si:ch73-1a9.4
chr17_-_52587598 0.82 ENSDART00000061497
si:ch211-173a9.6
si:ch211-173a9.6
chr20_+_4060839 0.82 ENSDART00000178565
TRIM67
tripartite motif containing 67
chr1_+_2190714 0.82 ENSDART00000132126
mbnl2
muscleblind-like splicing regulator 2
chr5_-_46329880 0.81 ENSDART00000156577
si:ch211-130m23.5
si:ch211-130m23.5
chr23_+_39606108 0.81 ENSDART00000109464
g0s2
G0/G1 switch 2
chr1_+_44439661 0.80 ENSDART00000100309
crybb1l2
crystallin, beta B1, like 2
chr12_-_8504278 0.79 ENSDART00000135865
egr2b
early growth response 2b
chr2_+_30916188 0.79 ENSDART00000137012
myom1a
myomesin 1a (skelemin)
chr20_-_26001288 0.78 ENSDART00000136518
ENSDART00000063177
capn3b
calpain 3b
chr21_-_26071773 0.78 ENSDART00000141382
rab34b
RAB34, member RAS oncogene family b
chr10_-_15128771 0.76 ENSDART00000101261
spp1
secreted phosphoprotein 1
chr4_+_2230701 0.76 ENSDART00000080439
cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr17_-_42213822 0.75 ENSDART00000187904
ENSDART00000180029
nkx2.2a
NK2 homeobox 2a
chr6_+_13933464 0.75 ENSDART00000109144
ptprnb
protein tyrosine phosphatase, receptor type, Nb
chr1_-_39909985 0.75 ENSDART00000181673
stox2a
storkhead box 2a
chr3_+_50310684 0.75 ENSDART00000112152
gas7a
growth arrest-specific 7a
chr5_+_28797771 0.74 ENSDART00000188845
ENSDART00000149066
si:ch211-186e20.7
si:ch211-186e20.7
chr4_+_1530287 0.74 ENSDART00000067446
slc38a4
solute carrier family 38, member 4
chr12_+_8373525 0.73 ENSDART00000152180
arid5b
AT-rich interaction domain 5B
chr14_-_36378494 0.73 ENSDART00000058503
gpm6aa
glycoprotein M6Aa
chr15_-_29586747 0.72 ENSDART00000076749
samsn1a
SAM domain, SH3 domain and nuclear localisation signals 1a
chr13_-_40726865 0.71 ENSDART00000099847
st3gal7
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr17_+_27434626 0.71 ENSDART00000052446
vgll2b
vestigial-like family member 2b
chr20_-_10120442 0.70 ENSDART00000144970
meis2b
Meis homeobox 2b
chr17_-_53440284 0.70 ENSDART00000126976
mycbp
c-myc binding protein
chr7_+_48805725 0.70 ENSDART00000166543
cpt1aa
carnitine palmitoyltransferase 1Aa (liver)
chr13_+_28903959 0.70 ENSDART00000166435
si:ch73-28h20.1
si:ch73-28h20.1
chr18_+_48423973 0.69 ENSDART00000184233
ENSDART00000147074
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr17_+_32571584 0.69 ENSDART00000087565
eva1a
eva-1 homolog A (C. elegans)
chr7_+_26132665 0.69 ENSDART00000129834
nat16
N-acetyltransferase 16
chr11_-_30158609 0.69 ENSDART00000006669
scml2
Scm polycomb group protein like 2
chr14_-_6931889 0.68 ENSDART00000166439
si:ch211-266k2.1
si:ch211-266k2.1
chr21_+_17110598 0.68 ENSDART00000101282
ENSDART00000191864
bcr
breakpoint cluster region
chr3_-_21280373 0.68 ENSDART00000003939
syngr1a
synaptogyrin 1a
chr21_-_39081107 0.68 ENSDART00000075935
vtnb
vitronectin b
chr4_-_13921185 0.68 ENSDART00000143202
ENSDART00000080334
yaf2
YY1 associated factor 2
chr15_-_28596507 0.67 ENSDART00000156800
si:ch211-225b7.5
si:ch211-225b7.5
chr18_+_40354998 0.67 ENSDART00000098791
ENSDART00000049171
sema6dl
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr24_-_4973765 0.67 ENSDART00000127597
zic1
zic family member 1 (odd-paired homolog, Drosophila)
chr4_-_13995766 0.66 ENSDART00000147955
prickle1b
prickle homolog 1b
chr7_+_20110336 0.66 ENSDART00000179395
zgc:114045
zgc:114045
chr21_+_26071874 0.66 ENSDART00000003001
ENSDART00000146573
rpl23a
ribosomal protein L23a
chr22_+_17784414 0.65 ENSDART00000188189
ENSDART00000145260
tm6sf2
transmembrane 6 superfamily member 2
chr6_-_41085692 0.65 ENSDART00000181463
srsf3a
serine/arginine-rich splicing factor 3a
chr1_+_37391716 0.65 ENSDART00000191986
sparcl1
SPARC-like 1
chr7_-_33023404 0.65 ENSDART00000052383
cd81a
CD81 molecule a
chr3_+_57038033 0.65 ENSDART00000162930
bahcc1a
BAH domain and coiled-coil containing 1a
chr6_+_21095918 0.65 ENSDART00000167225
spega
SPEG complex locus a
chr14_-_25040359 0.65 ENSDART00000162556
TMEM216
si:rp71-1d10.5
chr17_+_16755287 0.64 ENSDART00000080129
ston2
stonin 2
chr5_+_32345187 0.64 ENSDART00000147132
c9
complement component 9
chr6_+_37894220 0.64 ENSDART00000087311
oca2
oculocutaneous albinism II
chr9_+_3388099 0.64 ENSDART00000019910
dlx1a
distal-less homeobox 1a
chr8_-_13029297 0.63 ENSDART00000144305
dennd2da
DENN/MADD domain containing 2Da
chr11_-_30158191 0.63 ENSDART00000155278
ENSDART00000156121
scml2
Scm polycomb group protein like 2
chr14_+_33723309 0.63 ENSDART00000132488
apln
apelin
chr25_-_3228025 0.63 ENSDART00000165924
cib1
calcium and integrin binding 1 (calmyrin)
chr17_-_17130942 0.63 ENSDART00000064241
nrxn3a
neurexin 3a
chr10_+_9561066 0.62 ENSDART00000136281
si:ch211-243g18.2
si:ch211-243g18.2
chr20_+_27003558 0.62 ENSDART00000125688
si:dkey-177p2.18
si:dkey-177p2.18
chr9_+_3282369 0.62 ENSDART00000044128
hat1
histone acetyltransferase 1
chr3_-_28428198 0.61 ENSDART00000151546
rbfox1
RNA binding fox-1 homolog 1
chr18_-_16123222 0.61 ENSDART00000061189
sspn
sarcospan (Kras oncogene-associated gene)
chr23_+_21479958 0.60 ENSDART00000188302
ENSDART00000144320
si:dkey-1c11.1
si:dkey-1c11.1
chr8_-_14151051 0.59 ENSDART00000090427
si:dkey-6n6.1
si:dkey-6n6.1
chr10_+_31244619 0.59 ENSDART00000145562
ENSDART00000184412
robo4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr23_+_11347313 0.59 ENSDART00000135406
chl1a
cell adhesion molecule L1-like a
chr8_-_7093507 0.59 ENSDART00000045669
si:dkey-222n6.2
si:dkey-222n6.2
chr11_+_6819050 0.59 ENSDART00000104289
rab3ab
RAB3A, member RAS oncogene family, b
chr23_-_31763753 0.59 ENSDART00000053399
aldh8a1
aldehyde dehydrogenase 8 family, member A1
chr15_+_29123031 0.58 ENSDART00000133988
ENSDART00000060030
zgc:101731
zgc:101731
chr9_+_21722733 0.58 ENSDART00000102021
sox1a
SRY (sex determining region Y)-box 1a
chr16_+_14588141 0.58 ENSDART00000140469
ENSDART00000059984
ENSDART00000167411
ENSDART00000133566
deptor
DEP domain containing MTOR-interacting protein
chr2_+_5563077 0.58 ENSDART00000111220
mb21d2
Mab-21 domain containing 2
chr25_+_15647993 0.58 ENSDART00000186578
ENSDART00000031828
spon1b
spondin 1b
chr4_-_1824836 0.58 ENSDART00000111858
mrpl42
mitochondrial ribosomal protein L42
chr1_+_1599979 0.58 ENSDART00000097626
urp2
urotensin II-related peptide
chr23_+_36653376 0.58 ENSDART00000053189
gpr182
G protein-coupled receptor 182
chr25_-_25434479 0.57 ENSDART00000171589
hrasa
v-Ha-ras Harvey rat sarcoma viral oncogene homolog a
chr22_+_26400519 0.57 ENSDART00000159839
ENSDART00000144585
capn8
calpain 8
chr2_+_1487118 0.57 ENSDART00000147283
c8a
complement component 8, alpha polypeptide
chr15_-_47841259 0.57 ENSDART00000155384
kbtbd3
kelch repeat and BTB (POZ) domain containing 3
chr7_+_11197940 0.56 ENSDART00000081346
cemip
cell migration inducing protein, hyaluronan binding
chr19_+_25649626 0.56 ENSDART00000146947
tac1
tachykinin 1
chr20_+_6142433 0.55 ENSDART00000054084
ENSDART00000136986
ttr
transthyretin (prealbumin, amyloidosis type I)
chr15_+_36187434 0.55 ENSDART00000181536
ENSDART00000099501
ENSDART00000154432
masp1
mannan-binding lectin serine peptidase 1
chr3_-_37571601 0.55 ENSDART00000016407
arf2a
ADP-ribosylation factor 2a
chr7_-_31759394 0.55 ENSDART00000193040
igdcc4
immunoglobulin superfamily, DCC subclass, member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of foxa_foxa1_foxa2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 7.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
1.0 3.0 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.9 3.5 GO:0010226 response to lithium ion(GO:0010226)
0.7 2.8 GO:0061549 sympathetic ganglion development(GO:0061549)
0.5 1.4 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.4 1.3 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.4 3.6 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011)
0.4 1.2 GO:0042421 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.4 2.1 GO:0071800 podosome assembly(GO:0071800)
0.3 1.7 GO:0097272 ammonia homeostasis(GO:0097272)
0.3 1.0 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.3 1.4 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.3 0.8 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.3 1.9 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.3 1.6 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.3 2.9 GO:0019731 antibacterial humoral response(GO:0019731)
0.3 0.8 GO:0097264 self proteolysis(GO:0097264)
0.2 1.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 2.1 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.2 0.9 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.2 0.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.2 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.2 0.6 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.2 1.4 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.2 0.6 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.2 0.6 GO:0097052 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.2 1.8 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.2 0.5 GO:0042416 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.2 0.5 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.2 0.5 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.1 2.3 GO:0097320 membrane tubulation(GO:0097320)
0.1 1.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.5 GO:0006565 L-serine catabolic process(GO:0006565)
0.1 1.2 GO:0090109 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.1 0.6 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 0.5 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.6 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.5 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 1.5 GO:0001964 startle response(GO:0001964)
0.1 0.5 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.1 1.4 GO:0043462 regulation of ATPase activity(GO:0043462)
0.1 0.7 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.1 4.6 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 1.7 GO:0097178 ruffle assembly(GO:0097178)
0.1 1.3 GO:0032264 IMP salvage(GO:0032264)
0.1 1.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 0.5 GO:0003232 bulbus arteriosus development(GO:0003232)
0.1 0.6 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.6 GO:0042438 melanin biosynthetic process(GO:0042438)
0.1 0.9 GO:0021754 facial nucleus development(GO:0021754)
0.1 0.8 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.3 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 0.7 GO:0060612 adipose tissue development(GO:0060612)
0.1 2.1 GO:0006949 syncytium formation by plasma membrane fusion(GO:0000768) syncytium formation(GO:0006949)
0.1 0.6 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.7 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.1 0.2 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.1 0.4 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 1.7 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 0.8 GO:0048941 myelination of lateral line nerve axons(GO:0048897) posterior lateral line nerve glial cell differentiation(GO:0048931) myelination of posterior lateral line nerve axons(GO:0048932) lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048938) posterior lateral line nerve glial cell development(GO:0048941) posterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048942)
0.1 0.4 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 0.5 GO:0048730 epidermis morphogenesis(GO:0048730)
0.1 0.4 GO:2001239 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.6 GO:0072337 modified amino acid transport(GO:0072337)
0.1 0.4 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 1.4 GO:0019835 cytolysis(GO:0019835)
0.1 0.9 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 0.3 GO:0035475 angioblast cell migration involved in selective angioblast sprouting(GO:0035475)
0.1 0.2 GO:1903504 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.3 GO:0021588 cerebellum formation(GO:0021588)
0.0 0.9 GO:0009409 response to cold(GO:0009409)
0.0 0.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.2 GO:0031627 telomeric loop formation(GO:0031627)
0.0 0.2 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.4 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 1.6 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.5 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 1.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0019483 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.0 0.5 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 1.0 GO:0051923 sulfation(GO:0051923)
0.0 0.3 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:2000252 negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.5 GO:0060021 palate development(GO:0060021)
0.0 0.2 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 0.2 GO:0048662 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 1.0 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.5 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 2.2 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0 0.4 GO:0031641 regulation of myelination(GO:0031641)
0.0 1.9 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0061641 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.3 GO:0045453 bone resorption(GO:0045453)
0.0 0.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0019323 pentose catabolic process(GO:0019323)
0.0 0.8 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.7 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.1 GO:0061015 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.0 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.4 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 1.6 GO:0006096 glycolytic process(GO:0006096)
0.0 0.1 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.2 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.5 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.0 0.1 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.4 GO:0031167 rRNA methylation(GO:0031167)
0.0 1.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0032637 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.0 0.4 GO:0021986 habenula development(GO:0021986)
0.0 0.6 GO:0007586 digestion(GO:0007586)
0.0 0.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 1.2 GO:0006414 translational elongation(GO:0006414)
0.0 0.4 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.8 GO:0060348 bone development(GO:0060348)
0.0 0.4 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 1.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.6 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 1.3 GO:0042594 response to starvation(GO:0042594)
0.0 0.4 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.3 GO:0044273 sulfur compound catabolic process(GO:0044273)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.3 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.7 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.5 GO:0006956 complement activation(GO:0006956)
0.0 0.7 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.0 GO:0032847 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.0 0.7 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0021702 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0097107 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.7 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.3 GO:0006301 postreplication repair(GO:0006301)
0.0 0.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.6 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 0.0 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 1.6 GO:0006936 muscle contraction(GO:0006936)
0.0 0.1 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.4 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 0.3 GO:0016525 negative regulation of angiogenesis(GO:0016525) negative regulation of blood vessel morphogenesis(GO:2000181)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.3 1.2 GO:0016460 myosin II complex(GO:0016460)
0.3 2.1 GO:0001891 phagocytic cup(GO:0001891)
0.2 0.7 GO:0044216 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 0.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.4 GO:0043218 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.1 0.3 GO:0043614 multi-eIF complex(GO:0043614)
0.1 1.5 GO:0031209 SCAR complex(GO:0031209)
0.1 1.4 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.4 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 1.2 GO:0030315 T-tubule(GO:0030315)
0.1 1.2 GO:0030008 TRAPP complex(GO:0030008)
0.1 2.2 GO:0031672 A band(GO:0031672)
0.1 0.6 GO:0031526 brush border membrane(GO:0031526)
0.1 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 2.3 GO:0031012 extracellular matrix(GO:0031012)
0.1 0.6 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.6 GO:0045095 keratin filament(GO:0045095)
0.1 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 2.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.8 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.8 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.5 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.3 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.7 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 1.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.6 GO:0055037 recycling endosome(GO:0055037)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.7 GO:0030141 secretory granule(GO:0030141)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.4 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.9 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.2 GO:0008305 integrin complex(GO:0008305)
0.0 1.5 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.8 GO:0005844 polysome(GO:0005844)
0.0 0.7 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.5 GO:0043204 perikaryon(GO:0043204)
0.0 6.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 29.1 GO:0005576 extracellular region(GO:0005576)
0.0 1.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.0 GO:0043291 RAVE complex(GO:0043291)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0031704 apelin receptor binding(GO:0031704)
0.4 1.2 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.3 1.2 GO:0032038 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.3 1.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.3 1.4 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.3 1.3 GO:0031769 glucagon receptor binding(GO:0031769)
0.3 1.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.3 1.8 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.3 0.8 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.2 0.7 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.2 0.6 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.2 4.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 1.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.6 GO:0070052 collagen V binding(GO:0070052)
0.1 0.6 GO:0051380 norepinephrine binding(GO:0051380)
0.1 0.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.9 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.5 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.1 1.0 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 1.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.4 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 0.6 GO:0046592 polyamine oxidase activity(GO:0046592)
0.1 1.7 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.5 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.5 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.3 GO:0070643 vitamin D 25-hydroxylase activity(GO:0070643)
0.1 1.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 3.9 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.7 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 1.3 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.6 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 0.5 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 1.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.9 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.1 GO:0031834 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
0.0 1.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.4 GO:0005042 netrin receptor activity(GO:0005042)
0.0 1.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 1.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.6 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 1.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.7 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 1.1 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 2.7 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.8 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 2.3 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 3.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.7 GO:0019843 rRNA binding(GO:0019843)
0.0 2.1 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.0 4.9 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 3.2 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 6.5 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.0 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160) ionotropic glutamate receptor binding(GO:0035255)
0.0 0.0 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.5 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.1 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 20.2 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 4.5 PID AP1 PATHWAY AP-1 transcription factor network
0.1 1.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 2.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.2 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.6 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.2 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 1.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 2.9 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.1 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 0.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+