Project

PRJNA195909:zebrafish embryo and larva development

Navigation
Downloads

Results for foxd2_foxd5

Z-value: 1.30

Motif logo

logo of logo of

Transcription factors associated with foxd2_foxd5

Gene Symbol Gene ID Gene Info
foxd2
ENSDARG00000058133 forkhead box D2
foxd5
ENSDARG00000042485 forkhead box D5
foxd5
ENSDARG00000109712 forkhead box D5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxd2dr11_v1_chr8_+_19674369_196743690.845.0e-03Click!
foxd5dr11_v1_chr8_+_30452945_304529450.284.7e-01Click!

Activity profile of foxd2_foxd5 motif

Sorted Z-values of foxd2_foxd5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_12013043 3.54 ENSDART00000130692
cry1aa
cryptochrome circadian clock 1aa
chr14_+_21107032 2.91 ENSDART00000138319
ENSDART00000139103
ENSDART00000184735
aldob
aldolase b, fructose-bisphosphate
chr22_-_17595310 2.76 ENSDART00000099056
gpx4a
glutathione peroxidase 4a
chr14_+_11458044 2.66 ENSDART00000186425
si:ch211-153b23.5
si:ch211-153b23.5
chr14_+_11457500 2.58 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr8_-_16697615 2.58 ENSDART00000187929
rpe65b
retinal pigment epithelium-specific protein 65b
chr3_+_36424055 2.46 ENSDART00000170318
si:ch1073-443f11.2
si:ch1073-443f11.2
chr6_+_2097690 2.44 ENSDART00000193770
tgm2b
transglutaminase 2b
chr16_+_11724230 2.41 ENSDART00000060266
ceacam1
carcinoembryonic antigen-related cell adhesion molecule 1
chr8_+_16004551 2.26 ENSDART00000165141
elavl4
ELAV like neuron-specific RNA binding protein 4
chr11_+_8660158 2.15 ENSDART00000169141
tbl1xr1a
transducin (beta)-like 1 X-linked receptor 1a
chr17_+_21964472 2.11 ENSDART00000063704
ENSDART00000188904
crip3
cysteine-rich protein 3
chr1_-_30473422 2.08 ENSDART00000164202
igf2bp2b
insulin-like growth factor 2 mRNA binding protein 2b
chr18_-_46354269 2.05 ENSDART00000010813
foxa3
forkhead box A3
chr22_-_23668356 2.01 ENSDART00000167106
ENSDART00000159622
ENSDART00000163228
cfh
complement factor H
chr10_+_36650222 1.84 ENSDART00000126963
ucp3
uncoupling protein 3
chr25_+_29160102 1.84 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr5_-_14344647 1.80 ENSDART00000188456
tet3
tet methylcytosine dioxygenase 3
chr8_+_16004154 1.77 ENSDART00000134787
ENSDART00000172510
ENSDART00000141173
elavl4
ELAV like neuron-specific RNA binding protein 4
chr5_+_32206378 1.71 ENSDART00000126873
ENSDART00000051361
myhz2
myosin, heavy polypeptide 2, fast muscle specific
chr22_-_11438627 1.70 ENSDART00000007649
mid1ip1b
MID1 interacting protein 1b
chr12_-_30583668 1.70 ENSDART00000153406
casp7
caspase 7, apoptosis-related cysteine peptidase
chr6_-_8264751 1.63 ENSDART00000091628
ccdc151
coiled-coil domain containing 151
chr4_-_16412084 1.62 ENSDART00000188460
dcn
decorin
chr13_+_32144370 1.61 ENSDART00000020270
osr1
odd-skipped related transciption factor 1
chr5_+_26795465 1.59 ENSDART00000053001
tcn2
transcobalamin II
chr22_+_11756040 1.57 ENSDART00000105808
krt97
keratin 97
chr17_-_10838434 1.54 ENSDART00000064597
lgals3b
lectin, galactoside binding soluble 3b
chr23_-_4925641 1.46 ENSDART00000140861
ENSDART00000060718
taz
tafazzin
chr14_-_4121052 1.45 ENSDART00000167074
irf2
interferon regulatory factor 2
chr1_-_35924495 1.42 ENSDART00000184424
smad1
SMAD family member 1
chr25_+_19149241 1.37 ENSDART00000184982
ENSDART00000067324
mfge8b
milk fat globule-EGF factor 8 protein b
chr23_-_44219902 1.36 ENSDART00000185874
zgc:158659
zgc:158659
chr21_+_44684577 1.33 ENSDART00000099528
spry4
sprouty homolog 4 (Drosophila)
chr9_+_34127005 1.30 ENSDART00000167384
ENSDART00000078065
f5
coagulation factor V
chr8_-_13013123 1.26 ENSDART00000147802
dennd2da
DENN/MADD domain containing 2Da
chr4_-_25215968 1.25 ENSDART00000066932
ENSDART00000066933
itih2
inter-alpha-trypsin inhibitor heavy chain 2
chr3_-_50863370 1.24 ENSDART00000169771
ENSDART00000165083
pmp22a
peripheral myelin protein 22a
chr18_-_6803424 1.19 ENSDART00000142647
si:dkey-266m15.5
si:dkey-266m15.5
chr19_-_22387141 1.19 ENSDART00000151234
eppk1
epiplakin 1
chr5_+_67662430 1.19 ENSDART00000137700
ENSDART00000142586
si:dkey-70b23.2
si:dkey-70b23.2
chr24_+_22485710 1.16 ENSDART00000146058
si:dkey-40h20.1
si:dkey-40h20.1
chr2_-_30693742 1.16 ENSDART00000090292
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr23_-_26077038 1.14 ENSDART00000126299
gdi1
GDP dissociation inhibitor 1
chr20_-_27225876 1.14 ENSDART00000149204
ENSDART00000149732
si:dkey-85n7.7
si:dkey-85n7.7
chr22_+_5663529 1.13 ENSDART00000106141
tma7
translation machinery associated 7 homolog
chr17_-_10073926 1.11 ENSDART00000166081
ENSDART00000161574
zgc:109986
zgc:109986
chr20_+_36233873 1.05 ENSDART00000131867
cnih3
cornichon family AMPA receptor auxiliary protein 3
chr13_-_30662403 1.03 ENSDART00000012457
si:dkey-275b16.2
si:dkey-275b16.2
chr13_+_32446169 0.99 ENSDART00000143325
nt5c1ba
5'-nucleotidase, cytosolic IB a
chr21_+_35215810 0.97 ENSDART00000135256
ubtd2
ubiquitin domain containing 2
chr21_+_27416284 0.95 ENSDART00000077593
ENSDART00000108763
cfb
complement factor B
chr13_+_29773153 0.94 ENSDART00000144443
ENSDART00000133796
ENSDART00000141310
ENSDART00000139782
pax2a
paired box 2a
chr2_-_9748039 0.88 ENSDART00000134870
si:ch1073-170o4.1
si:ch1073-170o4.1
chr5_-_51756210 0.88 ENSDART00000163464
lhfpl2b
LHFPL tetraspan subfamily member 2b
chr24_+_7631797 0.87 ENSDART00000187464
cavin1b
caveolae associated protein 1b
chr6_-_55864687 0.87 ENSDART00000160991
cyp24a1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr4_-_12723585 0.87 ENSDART00000185639
mgst1.2
microsomal glutathione S-transferase 1.2
chr2_-_37956768 0.86 ENSDART00000034595
cbln10
cerebellin 10
chr8_-_15150131 0.85 ENSDART00000138253
bcar3
BCAR3, NSP family adaptor protein
chr14_-_40389699 0.85 ENSDART00000181581
ENSDART00000173398
pcdh19
protocadherin 19
chr12_-_34887943 0.83 ENSDART00000027379
bicral
BRD4 interacting chromatin remodeling complex associated protein like
chr23_-_20258490 0.83 ENSDART00000147326
lamb2
laminin, beta 2 (laminin S)
chr15_+_23911655 0.82 ENSDART00000156304
si:ch1073-145m9.1
si:ch1073-145m9.1
chr21_+_17110598 0.82 ENSDART00000101282
ENSDART00000191864
bcr
breakpoint cluster region
chr19_+_11984725 0.81 ENSDART00000185960
spag1a
sperm associated antigen 1a
chr9_+_30108641 0.78 ENSDART00000060174
jagn1a
jagunal homolog 1a
chr7_+_65387374 0.76 ENSDART00000188680
CLEC3A
C-type lectin domain family 3 member A
chr14_-_33894915 0.75 ENSDART00000143290
urp1
urotensin-related peptide 1
chr14_-_4120636 0.74 ENSDART00000059230
irf2
interferon regulatory factor 2
chr4_-_7212875 0.74 ENSDART00000161297
lrrn3b
leucine rich repeat neuronal 3b
chr19_-_31402429 0.73 ENSDART00000137292
tmem106bb
transmembrane protein 106Bb
chr16_-_35952789 0.73 ENSDART00000180118
eva1ba
eva-1 homolog Ba (C. elegans)
chr2_+_47906240 0.73 ENSDART00000122206
ftr23
finTRIM family, member 23
chr3_-_50139860 0.70 ENSDART00000101563
btr02
bloodthirsty-related gene family, member 2
chr4_-_21851473 0.70 ENSDART00000019748
lin7a
lin-7 homolog A (C. elegans)
chr15_+_28368644 0.70 ENSDART00000168453
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr16_-_38629208 0.70 ENSDART00000126705
eif3ea
eukaryotic translation initiation factor 3, subunit E, a
chr14_-_26377044 0.66 ENSDART00000022236
emx3
empty spiracles homeobox 3
chr16_-_7228276 0.66 ENSDART00000149030
nt5c3a
5'-nucleotidase, cytosolic IIIA
chr22_-_13042992 0.66 ENSDART00000028787
ahr1b
aryl hydrocarbon receptor 1b
chr24_-_35707552 0.65 ENSDART00000165199
mapre2
microtubule-associated protein, RP/EB family, member 2
chr20_-_9963713 0.65 ENSDART00000104234
gjd2b
gap junction protein delta 2b
chr4_+_12013642 0.65 ENSDART00000067281
cry1aa
cryptochrome circadian clock 1aa
chr5_-_11943750 0.64 ENSDART00000074979
rnft2
ring finger protein, transmembrane 2
chr6_-_32703317 0.64 ENSDART00000064833
mafaa
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa
chr15_+_24691088 0.63 ENSDART00000110618
LRRC75A
si:dkey-151p21.7
chr20_+_26881600 0.63 ENSDART00000174799
serpinb1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr5_+_43530388 0.63 ENSDART00000190254
ENSDART00000097618
ENSDART00000133006
si:dkey-40c11.2
si:dkey-40c11.2
chr2_+_36898982 0.63 ENSDART00000084859
rabgap1l2
RAB GTPase activating protein 1-like 2
chr1_-_37087966 0.62 ENSDART00000172111
ENSDART00000160056
nr3c2
nuclear receptor subfamily 3, group C, member 2
chr15_+_28368823 0.62 ENSDART00000142298
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr22_+_11867639 0.61 ENSDART00000144677
mras
muscle RAS oncogene homolog
chr16_-_44349845 0.60 ENSDART00000170932
rims2a
regulating synaptic membrane exocytosis 2a
chr23_-_16960972 0.59 ENSDART00000142546
cdc42l2
cell division cycle 42 like 2
chr14_-_1635296 0.59 ENSDART00000186658
LO018564.1

chr14_+_46410766 0.59 ENSDART00000032342
anxa5a
annexin A5a
chr2_-_5135125 0.58 ENSDART00000164039
ptmab
prothymosin, alpha b
chr19_+_32856907 0.57 ENSDART00000148232
rpl30
ribosomal protein L30
chr3_-_28828242 0.57 ENSDART00000151445
si:ch211-76l23.4
si:ch211-76l23.4
chr12_+_23424108 0.57 ENSDART00000077732
bambia
BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a
chr12_-_36260532 0.55 ENSDART00000022533
kcnj2a
potassium inwardly-rectifying channel, subfamily J, member 2a
chr7_+_32722227 0.55 ENSDART00000126565
si:ch211-150g13.3
si:ch211-150g13.3
chr17_+_8292892 0.54 ENSDART00000125728
si:ch211-236p5.3
si:ch211-236p5.3
chr9_-_23147026 0.53 ENSDART00000167266
lypd6b
LY6/PLAUR domain containing 6B
chr10_-_8294965 0.53 ENSDART00000167380
plpp1a
phospholipid phosphatase 1a
chr18_+_19974289 0.53 ENSDART00000090334
ENSDART00000192982
skor1b
SKI family transcriptional corepressor 1b
chr17_-_42213285 0.52 ENSDART00000140549
nkx2.2a
NK2 homeobox 2a
chr18_-_24988645 0.51 ENSDART00000136434
ENSDART00000085735
chd2
chromodomain helicase DNA binding protein 2
chr2_-_985417 0.51 ENSDART00000140540
si:ch211-241e1.3
si:ch211-241e1.3
chr3_+_41917499 0.51 ENSDART00000028673
lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr19_-_31522625 0.51 ENSDART00000158438
ENSDART00000035049
necab1
N-terminal EF-hand calcium binding protein 1
chr16_+_38119004 0.50 ENSDART00000132087
pogzb
pogo transposable element derived with ZNF domain b
chr5_-_67750907 0.49 ENSDART00000172097
b4galt4
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr1_-_656693 0.49 ENSDART00000170483
ENSDART00000166786
appa
amyloid beta (A4) precursor protein a
chr5_+_22970617 0.48 ENSDART00000192859
hmgn7
high mobility group nucleosomal binding domain 7
chr3_-_21280373 0.48 ENSDART00000003939
syngr1a
synaptogyrin 1a
chr6_-_19035749 0.47 ENSDART00000187714
sept9b
septin 9b
chr17_-_37052622 0.47 ENSDART00000186408
dnmt3ab
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr5_+_29671681 0.46 ENSDART00000043096
ak8
adenylate kinase 8
chr6_-_40098641 0.45 ENSDART00000017402
ip6k2b
inositol hexakisphosphate kinase 2b
chr19_+_43359075 0.45 ENSDART00000148287
ENSDART00000149856
ENSDART00000188236
ENSDART00000136695
ENSDART00000193859
yrk
Yes-related kinase
chr15_-_28677725 0.44 ENSDART00000060255
blmh
bleomycin hydrolase
chr20_+_34717403 0.44 ENSDART00000034252
pnocb
prepronociceptin b
chr9_-_21231297 0.44 ENSDART00000162578
pla1a
phospholipase A1 member A
chr3_-_16289826 0.43 ENSDART00000131972
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr16_+_46492994 0.43 ENSDART00000134734
rpz5
rapunzel 5
chr7_+_33314925 0.42 ENSDART00000148590
coro2ba
coronin, actin binding protein, 2Ba
chr4_+_7841627 0.42 ENSDART00000037997
ucmaa
upper zone of growth plate and cartilage matrix associated a
chr5_-_22027357 0.42 ENSDART00000023306
asb12a
ankyrin repeat and SOCS box-containing 12a
chr10_-_8295294 0.42 ENSDART00000075412
ENSDART00000163803
plpp1a
phospholipid phosphatase 1a
chr20_+_2950005 0.41 ENSDART00000135919
amd1
adenosylmethionine decarboxylase 1
chr15_-_16121496 0.41 ENSDART00000128624
sgk494a
uncharacterized serine/threonine-protein kinase SgK494a
chr8_+_32747612 0.39 ENSDART00000142824
hmcn2
hemicentin 2
chr3_+_34683096 0.38 ENSDART00000084432
dusp3b
dual specificity phosphatase 3b
chr22_-_6048054 0.38 ENSDART00000183239
CU468041.2

chr16_+_43139504 0.38 ENSDART00000065643
dbf4
DBF4 zinc finger
chr24_-_22756508 0.37 ENSDART00000035409
ENSDART00000146247
zc2hc1a
zinc finger, C2HC-type containing 1A
chr20_-_25436389 0.36 ENSDART00000153266
itsn2a
intersectin 2a
chr16_+_21330634 0.36 ENSDART00000191285
ENSDART00000183267
osbpl3b
oxysterol binding protein-like 3b
chr10_-_35236949 0.35 ENSDART00000145804
ypel2a
yippee-like 2a
chr15_+_32867420 0.34 ENSDART00000159442
dclk1b
doublecortin-like kinase 1b
chr20_+_27647436 0.34 ENSDART00000180557
ENSDART00000185628
mthfd1a
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1a, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
chr6_+_24661736 0.34 ENSDART00000169283
znf644b
zinc finger protein 644b
chr7_+_56703254 0.34 ENSDART00000184547
ENSDART00000004964
ENSDART00000147259
ENSDART00000134173
nqo1
NAD(P)H dehydrogenase, quinone 1
chr17_-_42213822 0.33 ENSDART00000187904
ENSDART00000180029
nkx2.2a
NK2 homeobox 2a
chr18_-_16181952 0.33 ENSDART00000157824
slc6a15
solute carrier family 6 (neutral amino acid transporter), member 15
chr25_+_24250247 0.33 ENSDART00000064646
tmem86a
transmembrane protein 86A
chr18_+_19419120 0.32 ENSDART00000025107
map2k1
mitogen-activated protein kinase kinase 1
chr6_+_54187643 0.31 ENSDART00000056830
pacsin1b
protein kinase C and casein kinase substrate in neurons 1b
chr13_+_32740509 0.31 ENSDART00000076423
ENSDART00000160138
sobpa
sine oculis binding protein homolog (Drosophila) a
chr8_-_16499508 0.30 ENSDART00000108659
ttc39a
tetratricopeptide repeat domain 39A
chr5_+_53009083 0.30 ENSDART00000157836
hint2
histidine triad nucleotide binding protein 2
chr5_-_29671586 0.30 ENSDART00000098336
spaca9
sperm acrosome associated 9
chr21_-_32284532 0.30 ENSDART00000190676
clk4b
CDC-like kinase 4b
chr19_+_816208 0.30 ENSDART00000093304
nrm
nurim
chr15_+_45563491 0.29 ENSDART00000191169
cldn15lb
claudin 15-like b
chr18_+_13837746 0.29 ENSDART00000169552
cdh13
cadherin 13, H-cadherin (heart)
chr5_-_61624693 0.29 ENSDART00000141323
si:dkey-261j4.4
si:dkey-261j4.4
chr22_-_9728208 0.29 ENSDART00000185962
si:dkey-286j17.4
si:dkey-286j17.4
chr18_-_5111449 0.28 ENSDART00000046902
pdcd10a
programmed cell death 10a
chr3_-_29506960 0.28 ENSDART00000141720
cyth4a
cytohesin 4a
chr8_+_26410197 0.28 ENSDART00000145836
ENSDART00000053447
ifrd2
interferon-related developmental regulator 2
chr3_+_25216790 0.28 ENSDART00000156544
c1qtnf6a
C1q and TNF related 6a
chr21_-_39327223 0.27 ENSDART00000115097
aifm5
apoptosis-inducing factor, mitochondrion-associated, 5
chr8_-_44586981 0.27 ENSDART00000026831
ENSDART00000113945
rsph14
radial spoke head 14 homolog
chr20_+_43083745 0.27 ENSDART00000139014
ENSDART00000153438
moxd1l
monooxygenase, DBH-like 1, like
chr14_+_36628131 0.27 ENSDART00000188625
ENSDART00000125345
TENM3
si:dkey-237h12.3
chr3_+_39566999 0.26 ENSDART00000146867
aldoaa
aldolase a, fructose-bisphosphate, a
chr10_+_34315719 0.26 ENSDART00000135303
stard13a
StAR-related lipid transfer (START) domain containing 13a
chr5_-_3684402 0.25 ENSDART00000184354
FO704648.1

chr13_-_18195942 0.25 ENSDART00000079902
slc25a16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr13_-_4707018 0.25 ENSDART00000128422
oit3
oncoprotein induced transcript 3
chr20_-_51355465 0.25 ENSDART00000151620
ENSDART00000151690
ENSDART00000110289
tcte1
t-complex-associated-testis-expressed 1
chr22_-_15562933 0.25 ENSDART00000141528
ankmy1
ankyrin repeat and MYND domain containing 1
chr11_+_41858807 0.23 ENSDART00000161605
iffo2b
intermediate filament family orphan 2b
chr5_+_13385837 0.23 ENSDART00000191190
ccl19a.1
chemokine (C-C motif) ligand 19a, tandem duplicate 1
chr18_+_36664654 0.22 ENSDART00000128707
ENSDART00000098972
capn12
calpain 12
chr14_+_34966598 0.22 ENSDART00000004550
rnf145a
ring finger protein 145a
chr17_-_24564674 0.22 ENSDART00000105435
ENSDART00000135086
abch1
ATP-binding cassette, sub-family H, member 1
chr16_-_19373310 0.21 ENSDART00000148294
dnah11
dynein, axonemal, heavy chain 11
chr12_-_20120702 0.21 ENSDART00000153387
ENSDART00000158412
ENSDART00000112768
ubald1a
UBA-like domain containing 1a
chr19_+_46222428 0.20 ENSDART00000183984
vps28
vacuolar protein sorting 28 (yeast)
chr8_-_46457233 0.20 ENSDART00000113214
sult1st7
sulfotransferase family 1, cytosolic sulfotransferase 7
chr6_+_9870192 0.19 ENSDART00000150894
MPP4 (1 of many)
si:ch211-222n4.6
chr5_+_54400971 0.19 ENSDART00000169695
bspry
B-box and SPRY domain containing
chr12_-_22524388 0.18 ENSDART00000020942
shbg
sex hormone-binding globulin
chr2_-_37960688 0.18 ENSDART00000055565
cbln14
cerebellin 14
chr15_+_24212847 0.18 ENSDART00000155502
sez6b
seizure related 6 homolog b
chr16_-_29334672 0.18 ENSDART00000162835
bcan
brevican
chr24_+_5840258 0.18 ENSDART00000087034
trpc1
transient receptor potential cation channel, subfamily C, member 1
chr1_+_33697170 0.18 ENSDART00000131664
NSUN3
NOP2/Sun RNA methyltransferase family member 3
chr6_-_40697585 0.18 ENSDART00000113196
si:ch211-157b11.14
si:ch211-157b11.14
chr15_+_45563656 0.17 ENSDART00000157501
cldn15lb
claudin 15-like b
chr8_+_23142946 0.17 ENSDART00000152933
si:ch211-196c10.13
si:ch211-196c10.13
chr25_+_4760489 0.17 ENSDART00000167399
FP245455.1

chr11_+_14284866 0.17 ENSDART00000163729
si:ch211-262i1.3
si:ch211-262i1.3
chr22_-_15280638 0.17 ENSDART00000063008
mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr6_+_40671336 0.17 ENSDART00000111639
ENSDART00000186617
rereb
arginine-glutamic acid dipeptide (RE) repeats b
chr5_+_35398745 0.16 ENSDART00000098010
ptger4b
prostaglandin E receptor 4 (subtype EP4) b

Network of associatons between targets according to the STRING database.

First level regulatory network of foxd2_foxd5

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0048785 hatching gland development(GO:0048785)
0.6 2.6 GO:1901827 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.5 1.6 GO:0048389 intermediate mesoderm development(GO:0048389)
0.5 1.6 GO:0015889 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.4 1.8 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.3 1.5 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.3 0.9 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.3 0.8 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3 0.8 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.2 1.8 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 1.2 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.2 0.6 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
0.1 0.7 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 3.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 1.3 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1 1.5 GO:0046471 cardiolipin metabolic process(GO:0032048) phosphatidylglycerol metabolic process(GO:0046471)
0.1 0.6 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.9 GO:0021588 cerebellum formation(GO:0021588)
0.1 2.4 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.9 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.1 0.3 GO:1903358 regulation of Golgi organization(GO:1903358)
0.1 1.9 GO:0014823 response to activity(GO:0014823)
0.1 0.3 GO:0042420 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.1 0.5 GO:0055016 hypochord development(GO:0055016)
0.1 0.3 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 1.0 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.7 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 0.5 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 1.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.6 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 0.4 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 0.6 GO:0050819 negative regulation of coagulation(GO:0050819)
0.1 1.6 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.4 GO:0090497 mesenchymal cell migration(GO:0090497)
0.1 0.3 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.1 0.4 GO:2000105 positive regulation of DNA-dependent DNA replication(GO:2000105)
0.1 1.7 GO:0097194 execution phase of apoptosis(GO:0097194)
0.1 1.0 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 1.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.1 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.0 0.8 GO:0016203 muscle attachment(GO:0016203)
0.0 0.4 GO:0008216 spermidine metabolic process(GO:0008216)
0.0 0.7 GO:0032418 lysosome localization(GO:0032418)
0.0 2.6 GO:0072175 epithelial tube formation(GO:0072175)
0.0 1.8 GO:0006096 glycolytic process(GO:0006096)
0.0 1.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 1.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.9 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.1 GO:0072020 proximal straight tubule development(GO:0072020)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.3 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.2 GO:0034695 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.3 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.0 1.7 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.9 GO:0007599 hemostasis(GO:0007599)
0.0 0.4 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.0 0.8 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.7 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.5 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 2.9 GO:0006979 response to oxidative stress(GO:0006979)
0.0 0.4 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.1 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.0 0.2 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.1 GO:0090342 regulation of cell aging(GO:0090342)
0.0 1.1 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.5 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.1 GO:0050968 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 3.9 GO:0006914 autophagy(GO:0006914)
0.0 1.4 GO:0061515 myeloid cell development(GO:0061515)
0.0 0.9 GO:0006956 complement activation(GO:0006956) protein activation cascade(GO:0072376)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.9 GO:0007338 single fertilization(GO:0007338)
0.0 0.1 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:1903828 negative regulation of cellular protein localization(GO:1903828)
0.0 0.0 GO:0003218 cardiac left ventricle morphogenesis(GO:0003214) cardiac left ventricle formation(GO:0003218)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0001772 immunological synapse(GO:0001772)
0.2 0.7 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.7 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.1 1.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 1.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.2 GO:0045095 keratin filament(GO:0045095)
0.1 0.3 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.1 4.0 GO:0043204 perikaryon(GO:0043204)
0.1 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 1.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.7 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 1.8 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.8 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.6 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 1.9 GO:0005882 intermediate filament(GO:0005882)
0.0 0.7 GO:0051233 spindle midzone(GO:0051233)
0.0 0.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0097546 ciliary base(GO:0097546)
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.4 GO:0043679 axon terminus(GO:0043679)
0.0 0.5 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.7 GO:0031902 late endosome membrane(GO:0031902)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.6 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.6 2.8 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.5 1.8 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.4 3.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.4 1.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.3 0.9 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.3 1.5 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.3 1.8 GO:0004743 pyruvate kinase activity(GO:0004743)
0.3 1.5 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.3 1.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 0.9 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 0.9 GO:0070643 vitamin D 25-hydroxylase activity(GO:0070643)
0.2 1.0 GO:0046592 polyamine oxidase activity(GO:0046592)
0.2 1.6 GO:0031419 cobalamin binding(GO:0031419)
0.2 1.2 GO:0019215 intermediate filament binding(GO:0019215)
0.2 0.7 GO:0097016 L27 domain binding(GO:0097016)
0.2 0.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.7 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 1.4 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 2.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.5 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.3 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 0.5 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 1.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.4 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.3 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.6 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.3 GO:0016803 ether hydrolase activity(GO:0016803)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 1.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.8 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.5 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.3 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 2.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 2.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 2.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.5 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.3 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.1 GO:0045296 cadherin binding(GO:0045296)
0.0 0.5 GO:0046332 SMAD binding(GO:0046332)
0.0 1.7 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.4 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 0.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 0.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.6 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 1.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.8 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 1.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type