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PRJNA195909:zebrafish embryo and larva development

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Results for foxn1

Z-value: 1.63

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Transcription factors associated with foxn1

Gene Symbol Gene ID Gene Info
foxn1
ENSDARG00000011879 forkhead box N1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxn1dr11_v1_chr15_-_28161224_281612240.703.6e-02Click!

Activity profile of foxn1 motif

Sorted Z-values of foxn1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_+_19590006 3.03 ENSDART00000021231
slmapb
sarcolemma associated protein b
chr6_+_40992409 2.08 ENSDART00000151419
tgfa
transforming growth factor, alpha
chr20_-_6196989 1.86 ENSDART00000013343
b4galt6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr14_+_22457230 1.86 ENSDART00000019296
gdf9
growth differentiation factor 9
chr17_-_2584423 1.85 ENSDART00000013506
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr3_+_58472305 1.78 ENSDART00000154122
si:ch211-165g14.1
si:ch211-165g14.1
chr21_+_4256291 1.74 ENSDART00000148138
lrrc8aa
leucine rich repeat containing 8 VRAC subunit Aa
chr18_-_1270220 1.74 ENSDART00000193754
ugt5f1
UDP glucuronosyltransferase 5 family, polypeptide F1
chr3_+_7763114 1.69 ENSDART00000057434
hook2
hook microtubule-tethering protein 2
chr11_+_18183220 1.65 ENSDART00000113468
LO018315.10

chr14_-_46198373 1.64 ENSDART00000031640
ENSDART00000132966
zgc:113425
zgc:113425
chr13_-_51247529 1.64 ENSDART00000191774
ENSDART00000083788
AL929217.1

chr23_+_6586467 1.63 ENSDART00000081763
ENSDART00000121480
rbm38
RNA binding motif protein 38
chr19_-_6193448 1.59 ENSDART00000151405
erf
Ets2 repressor factor
chr16_-_51072406 1.56 ENSDART00000083777
ago3a
argonaute RISC catalytic component 3a
chr21_+_18405585 1.51 ENSDART00000139318
si:dkey-1d7.3
si:dkey-1d7.3
chr23_+_35650771 1.50 ENSDART00000005158
ccnt1
cyclin T1
chr5_-_18962794 1.44 ENSDART00000145210
ankle2
ankyrin repeat and LEM domain containing 2
chr19_-_6193067 1.44 ENSDART00000092656
ENSDART00000140347
erf
Ets2 repressor factor
chr17_+_44030692 1.43 ENSDART00000049503
peli2
pellino E3 ubiquitin protein ligase family member 2
chr22_-_38459316 1.41 ENSDART00000149683
ENSDART00000098461
ptk7a
protein tyrosine kinase 7a
chr5_-_52216170 1.39 ENSDART00000158542
ENSDART00000192981
lnpep
leucyl/cystinyl aminopeptidase
chr23_-_31400792 1.38 ENSDART00000132736
lca5
Leber congenital amaurosis 5
chr9_+_21793565 1.38 ENSDART00000134915
rev1
REV1, polymerase (DNA directed)
chr2_+_35732652 1.37 ENSDART00000052666
rasal2
RAS protein activator like 2
chr8_+_7778770 1.33 ENSDART00000171325
tfe3a
transcription factor binding to IGHM enhancer 3a
chr3_-_18805225 1.33 ENSDART00000133471
ENSDART00000131758
msrb1a
methionine sulfoxide reductase B1a
chr23_+_30898013 1.30 ENSDART00000146859
cables2a
Cdk5 and Abl enzyme substrate 2a
chr15_+_34963316 1.27 ENSDART00000153840
si:ch73-95l15.5
si:ch73-95l15.5
chr7_+_24153070 1.27 ENSDART00000076735
lrp10
low density lipoprotein receptor-related protein 10
chr25_+_7346800 1.26 ENSDART00000154404
peak1
pseudopodium-enriched atypical kinase 1
chr16_+_50741154 1.25 ENSDART00000101627
IGLON5
zgc:110372
chr10_+_37500234 1.20 ENSDART00000132096
ENSDART00000099473
msi2a
musashi RNA-binding protein 2a
chr5_-_30382925 1.20 ENSDART00000125381
gig2o
grass carp reovirus (GCRV)-induced gene 2o
chr8_+_36503797 1.19 ENSDART00000184785
slc7a4
solute carrier family 7, member 4
chr17_+_24064014 1.17 ENSDART00000182782
ENSDART00000139063
ENSDART00000132755
b3gnt2b
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr19_+_29303847 1.17 ENSDART00000009149
maco1a
macoilin 1a
chr10_-_35177257 1.16 ENSDART00000077426
pom121
POM121 transmembrane nucleoporin
chr13_+_23104134 1.13 ENSDART00000110266
pik3ap1
phosphoinositide-3-kinase adaptor protein 1
chr17_-_16324565 1.12 ENSDART00000030835
hmbox1a
homeobox containing 1a
chr2_+_35733335 1.12 ENSDART00000113489
rasal2
RAS protein activator like 2
chr7_+_34592526 1.11 ENSDART00000173959
fhod1
formin homology 2 domain containing 1
chr25_+_2776511 1.11 ENSDART00000115280
neo1b
neogenin 1b
chr14_+_21754521 1.08 ENSDART00000111839
kdm2ab
lysine (K)-specific demethylase 2Ab
chr2_+_42871831 1.07 ENSDART00000171393
efr3a
EFR3 homolog A (S. cerevisiae)
chr1_-_25144439 1.06 ENSDART00000132355
fbxw7
F-box and WD repeat domain containing 7
chr6_-_7686594 1.05 ENSDART00000091836
ENSDART00000151697
ubn2a
ubinuclein 2a
chr8_+_52530889 1.05 ENSDART00000127729
ENSDART00000170360
ENSDART00000162687
stambpb
STAM binding protein b
chr20_-_50014936 1.05 ENSDART00000148892
extl3
exostosin-like glycosyltransferase 3
chr2_-_48255843 1.04 ENSDART00000056277
gigyf2
GRB10 interacting GYF protein 2
chr1_+_44523516 1.04 ENSDART00000147702
zdhhc5a
zinc finger, DHHC-type containing 5a
chr15_-_37104165 1.03 ENSDART00000165867
zmp:0000001114
zmp:0000001114
chr3_+_18840810 1.03 ENSDART00000181137
ENSDART00000128626
ENSDART00000133332
tmem104
transmembrane protein 104
chr9_-_41090048 1.02 ENSDART00000131681
ENSDART00000182552
asnsd1
asparagine synthetase domain containing 1
chr22_-_10156581 1.02 ENSDART00000168304
rbck1
RanBP-type and C3HC4-type zinc finger containing 1
chr19_-_10295173 1.00 ENSDART00000136697
cnot3b
CCR4-NOT transcription complex, subunit 3b
chr10_+_16501699 1.00 ENSDART00000121864
slc27a6
solute carrier family 27 (fatty acid transporter), member 6
chr17_-_23895026 1.00 ENSDART00000122108
pdzd8
PDZ domain containing 8
chr19_-_46088429 1.00 ENSDART00000161385
ptdss1b
phosphatidylserine synthase 1b
chr14_-_40850481 0.99 ENSDART00000173236
elf1
E74-like ETS transcription factor 1
chr6_+_59832786 0.99 ENSDART00000154985
ENSDART00000102148
ddx3b
DEAD (Asp-Glu-Ala-Asp) box helicase 3b
chr1_+_41690402 0.99 ENSDART00000177298
fbxo41
F-box protein 41
chr4_-_77260727 0.99 ENSDART00000075770
zgc:162948
zgc:162948
chr16_+_48460873 0.98 ENSDART00000159902
ext1a
exostosin glycosyltransferase 1a
chr18_-_1258777 0.97 ENSDART00000077106
ENSDART00000129065
ugt5f1
UDP glucuronosyltransferase 5 family, polypeptide F1
chr23_-_35347714 0.97 ENSDART00000161770
ENSDART00000165615
cpne9
copine family member IX
chr9_-_8895130 0.96 ENSDART00000144673
ENSDART00000138527
rab20
RAB20, member RAS oncogene family
chr2_-_2096055 0.95 ENSDART00000126566
slc22a23
solute carrier family 22, member 23
chr21_+_1119046 0.93 ENSDART00000184678
CABZ01088049.1

chr4_-_74998614 0.93 ENSDART00000162529
zgc:172139
zgc:172139
chr8_+_36500061 0.91 ENSDART00000185840
slc7a4
solute carrier family 7, member 4
chr1_+_34203817 0.90 ENSDART00000191432
ENSDART00000046094
arl6
ADP-ribosylation factor-like 6
chr13_+_35925490 0.89 ENSDART00000046115
mfsd2aa
major facilitator superfamily domain containing 2aa
chr4_-_8152746 0.88 ENSDART00000012928
ENSDART00000177482
wnk1b
WNK lysine deficient protein kinase 1b
chr12_+_2804505 0.87 ENSDART00000152193
mms19
MMS19 homolog, cytosolic iron-sulfur assembly component
chr5_+_51248784 0.86 ENSDART00000159571
ENSDART00000189513
ENSDART00000092285
msh3
mutS homolog 3 (E. coli)
chr3_-_15081874 0.86 ENSDART00000192532
nme4
NME/NM23 nucleoside diphosphate kinase 4
chr4_-_18281070 0.85 ENSDART00000135330
ENSDART00000179075
ENSDART00000046871
uhrf1bp1l
UHRF1 binding protein 1-like
chr16_+_23531583 0.85 ENSDART00000146708
adar
adenosine deaminase, RNA-specific
chr21_+_21279159 0.85 ENSDART00000148346
itpkca
inositol-trisphosphate 3-kinase Ca
chr24_+_21092156 0.85 ENSDART00000028542
ccdc191
coiled-coil domain containing 191
chr3_-_29891456 0.84 ENSDART00000151677
ENSDART00000014021
slc25a39
solute carrier family 25, member 39
chr21_-_3700334 0.84 ENSDART00000137844
atp8b1
ATPase phospholipid transporting 8B1
chr2_+_44615000 0.84 ENSDART00000188826
ENSDART00000113232
yeats2
YEATS domain containing 2
chr5_+_23045096 0.83 ENSDART00000171719
atrxl
alpha thalassemia/mental retardation syndrome X-linked, like
chr19_-_7272921 0.83 ENSDART00000102075
ENSDART00000132887
ENSDART00000130234
ENSDART00000193535
ENSDART00000136528
rxrba
retinoid x receptor, beta a
chr3_-_29891218 0.82 ENSDART00000142118
slc25a39
solute carrier family 25, member 39
chr6_+_33885828 0.82 ENSDART00000179994
gpbp1l1
GC-rich promoter binding protein 1-like 1
chr22_+_26703026 0.82 ENSDART00000158756
crebbpa
CREB binding protein a
chr5_+_29794058 0.81 ENSDART00000045410
thy1
Thy-1 cell surface antigen
chr8_-_25846188 0.80 ENSDART00000128829
efhd2
EF-hand domain family, member D2
chr12_-_25150239 0.78 ENSDART00000038415
ENSDART00000135368
rhoq
ras homolog family member Q
chr7_+_69528850 0.77 ENSDART00000109507
RAP1GDS1
Rap1 GTPase-GDP dissociation stimulator 1
chr9_-_46415847 0.77 ENSDART00000009790
cx43.4
connexin 43.4
chr18_+_19990412 0.77 ENSDART00000155054
ENSDART00000090310
pias1b
protein inhibitor of activated STAT, 1b
chr20_-_13625588 0.77 ENSDART00000078893
sytl3
synaptotagmin-like 3
chr21_-_4849029 0.77 ENSDART00000168930
ENSDART00000151019
notch1a
notch 1a
chr5_-_35200590 0.76 ENSDART00000051271
fcho2
FCH domain only 2
chr10_+_29137482 0.76 ENSDART00000178280
picalma
phosphatidylinositol binding clathrin assembly protein a
chr11_-_23687158 0.76 ENSDART00000189599
pik3c2b
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr13_+_2442841 0.75 ENSDART00000114456
ENSDART00000137124
ENSDART00000193737
ENSDART00000189722
ENSDART00000187485
arfgef3
ARFGEF family member 3
chr25_+_3549841 0.75 ENSDART00000164030
ccdc77
coiled-coil domain containing 77
chr5_-_52215926 0.75 ENSDART00000163973
ENSDART00000193602
lnpep
leucyl/cystinyl aminopeptidase
chr12_-_10674606 0.75 ENSDART00000157919
med24
mediator complex subunit 24
chr13_+_18321140 0.75 ENSDART00000180947
eif4e1c
eukaryotic translation initiation factor 4E family member 1c
chr11_-_38083397 0.75 ENSDART00000086516
ENSDART00000184033
klhdc8a
kelch domain containing 8A
chr8_+_1284784 0.75 ENSDART00000061663
fbxl17
F-box and leucine-rich repeat protein 17
chr22_+_26290209 0.75 ENSDART00000060898
mrps28
mitochondrial ribosomal protein S28
chr5_-_68244564 0.75 ENSDART00000169350
CABZ01083944.1

chr7_+_13491452 0.74 ENSDART00000053535
arih1l
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like
chr19_+_9232676 0.74 ENSDART00000136957
kmt2ba
lysine (K)-specific methyltransferase 2Ba
chr21_+_3093419 0.73 ENSDART00000162520
SHC3
SHC adaptor protein 3
chr18_+_18879733 0.73 ENSDART00000019581
arih1
ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)
chr19_+_7173613 0.71 ENSDART00000001331
hsd17b8
hydroxysteroid (17-beta) dehydrogenase 8
chr10_-_15854743 0.71 ENSDART00000092343
tjp2a
tight junction protein 2a (zona occludens 2)
chr4_+_23117557 0.71 ENSDART00000066909
slc35e3
solute carrier family 35, member E3
chr9_+_8894788 0.70 ENSDART00000132068
naxd
NAD(P)HX dehydratase
chr19_-_29303788 0.70 ENSDART00000112167
srfbp1
serum response factor binding protein 1
chr20_+_51730658 0.69 ENSDART00000010271
aida
axin interactor, dorsalization associated
chr13_-_4018888 0.69 ENSDART00000058238
tjap1
tight junction associated protein 1 (peripheral)
chr17_+_37301860 0.69 ENSDART00000181531
ENSDART00000075978
elmsan1b
ELM2 and Myb/SANT-like domain containing 1b
chr16_-_31351419 0.69 ENSDART00000178298
ENSDART00000018091
mroh1
maestro heat-like repeat family member 1
chr15_-_34878388 0.69 ENSDART00000154094
mgat1a
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a
chr2_+_16696052 0.68 ENSDART00000022356
ENSDART00000164329
ppp1r7
protein phosphatase 1, regulatory (inhibitor) subunit 7
chr8_+_18010978 0.68 ENSDART00000039887
ENSDART00000144532
ssbp3b
single stranded DNA binding protein 3b
chr21_-_35325466 0.68 ENSDART00000134780
ENSDART00000145930
ENSDART00000076715
ENSDART00000065341
ENSDART00000162189
ublcp1
ubiquitin-like domain containing CTD phosphatase 1
chr4_-_72287764 0.68 ENSDART00000125452
ENSDART00000189437
si:cabz01071911.3
si:cabz01071911.3
chr8_+_18010568 0.67 ENSDART00000121984
ssbp3b
single stranded DNA binding protein 3b
chr16_-_40459104 0.67 ENSDART00000032389
plekhf2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr20_-_9428021 0.67 ENSDART00000025330
rdh14b
retinol dehydrogenase 14b
chr6_+_12504462 0.66 ENSDART00000171460
stk24b
serine/threonine kinase 24b (STE20 homolog, yeast)
chr7_-_60351876 0.66 ENSDART00000098563
plcb3
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr4_-_12102025 0.66 ENSDART00000048391
ENSDART00000023894
braf
B-Raf proto-oncogene, serine/threonine kinase
chr21_-_14175838 0.66 ENSDART00000111659
whrna
whirlin a
chr12_+_19320657 0.65 ENSDART00000100075
ENSDART00000066389
tmem184ba
transmembrane protein 184ba
chr7_-_60351537 0.64 ENSDART00000159875
plcb3
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr21_+_11885404 0.64 ENSDART00000092015
dcaf12
DDB1 and CUL4 associated factor 12
chr2_+_38055529 0.64 ENSDART00000145642
si:rp71-1g18.1
si:rp71-1g18.1
chr7_+_23495986 0.64 ENSDART00000190739
ENSDART00000115299
ENSDART00000101423
ENSDART00000142401
zgc:109889
zgc:109889
chr15_-_23908605 0.64 ENSDART00000185578
usp32
ubiquitin specific peptidase 32
chr6_+_34038963 0.63 ENSDART00000057732
ENSDART00000192496
ap1m3
adaptor-related protein complex 1, mu 3 subunit
chr5_+_63288599 0.63 ENSDART00000140065
si:ch73-37h15.2
si:ch73-37h15.2
chr3_-_32180796 0.63 ENSDART00000133191
ENSDART00000055308
pih1d1
PIH1 domain containing 1
chr23_-_10786400 0.62 ENSDART00000055038
rybpa
RING1 and YY1 binding protein a
chr18_+_39106722 0.61 ENSDART00000122377
bcl2l10
BCL2 like 10
chr2_-_32386598 0.60 ENSDART00000145575
ubtfl
upstream binding transcription factor, like
chr19_+_26681848 0.60 ENSDART00000138322
si:dkey-27c15.3
si:dkey-27c15.3
chr13_+_32454262 0.60 ENSDART00000057421
rdh14a
retinol dehydrogenase 14a
chr16_+_11242443 0.59 ENSDART00000024935
gsk3ab
glycogen synthase kinase 3 alpha b
chr15_-_28161224 0.59 ENSDART00000174540
foxn1
forkhead box N1
chr10_-_76352 0.59 ENSDART00000186560
ENSDART00000144722
dyrk1aa
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, a
chr7_-_5070794 0.59 ENSDART00000097877
ltb4r2a
leukotriene B4 receptor 2a
chr19_+_20495249 0.58 ENSDART00000090810
kcnh8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr15_-_23908779 0.58 ENSDART00000088808
usp32
ubiquitin specific peptidase 32
chr22_+_1786230 0.58 ENSDART00000169318
ENSDART00000164948
znf1154
zinc finger protein 1154
chr25_+_7532811 0.58 ENSDART00000161593
ptdss2
phosphatidylserine synthase 2
chr20_+_37300699 0.57 ENSDART00000067053
vta1
vesicle (multivesicular body) trafficking 1
chr10_-_35108683 0.56 ENSDART00000049633
zgc:110006
zgc:110006
chr18_+_16715864 0.56 ENSDART00000079758
eif4g2b
eukaryotic translation initiation factor 4, gamma 2b
chr25_+_3549401 0.55 ENSDART00000166312
ccdc77
coiled-coil domain containing 77
chr3_+_15773991 0.53 ENSDART00000089923
znf652
zinc finger protein 652
chr7_+_40083601 0.52 ENSDART00000099046
zgc:112356
zgc:112356
chr5_+_35463688 0.51 ENSDART00000142525
ENSDART00000131286
erlin2
ER lipid raft associated 2
chr10_+_3428194 0.51 ENSDART00000081599
ptpn11a
protein tyrosine phosphatase, non-receptor type 11, a
chr19_+_5134624 0.51 ENSDART00000151324
si:dkey-89b17.4
si:dkey-89b17.4
chr5_+_26075230 0.49 ENSDART00000098473
klf9
Kruppel-like factor 9
chr10_+_375042 0.49 ENSDART00000171854
si:ch1073-303d10.1
si:ch1073-303d10.1
chr8_-_18010735 0.49 ENSDART00000125014
acot11b
acyl-CoA thioesterase 11b
chr16_-_2390931 0.48 ENSDART00000149463
hace1
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
chr17_-_8656155 0.48 ENSDART00000148990
ctbp2a
C-terminal binding protein 2a
chr5_-_19932621 0.48 ENSDART00000088881
git2a
G protein-coupled receptor kinase interacting ArfGAP 2a
chr7_+_66884291 0.48 ENSDART00000187499
sbf2
SET binding factor 2
chr8_-_21071711 0.48 ENSDART00000111600
ENSDART00000135204
ENSDART00000131371
ENSDART00000146532
ENSDART00000137606
zgc:112962
zgc:112962
chr14_-_21123325 0.48 ENSDART00000180889
ENSDART00000188539
si:dkey-74k8.4
si:dkey-74k8.4
chr4_-_4751981 0.47 ENSDART00000147436
ENSDART00000092984
ENSDART00000158466
creb3l2
cAMP responsive element binding protein 3-like 2
chr9_-_41090343 0.46 ENSDART00000187769
ENSDART00000180078
ENSDART00000166785
asnsd1
asparagine synthetase domain containing 1
chr21_-_45363871 0.46 ENSDART00000075443
ENSDART00000182078
ENSDART00000151106
PPP2CA
zgc:56064
chr21_+_26028947 0.45 ENSDART00000028007
supt6h
SPT6 homolog, histone chaperone
chr18_-_41160975 0.45 ENSDART00000187517
CABZ01005876.1

chr19_-_4851411 0.45 ENSDART00000110398
fbxl20
F-box and leucine-rich repeat protein 20
chr16_-_26855936 0.45 ENSDART00000167320
ENSDART00000078119
ino80c
INO80 complex subunit C
chr12_-_4632519 0.45 ENSDART00000110514
prr12a
proline rich 12a
chr5_+_11812089 0.45 ENSDART00000111359
fbxo21
F-box protein 21
chr22_-_817479 0.44 ENSDART00000123487
zgc:153675
zgc:153675
chr2_-_42492201 0.44 ENSDART00000180762
ENSDART00000009093
esyt2a
extended synaptotagmin-like protein 2a
chr25_+_34845115 0.44 ENSDART00000061996
tmem231
transmembrane protein 231
chr17_+_10593398 0.43 ENSDART00000168897
ENSDART00000193989
ENSDART00000191664
ENSDART00000167188
mapkbp1
mitogen-activated protein kinase binding protein 1
chr15_-_47458034 0.43 ENSDART00000168527
inppl1a
inositol polyphosphate phosphatase-like 1a
chr23_-_19486571 0.43 ENSDART00000009092
fam208ab
family with sequence similarity 208, member Ab
chr7_+_34236238 0.43 ENSDART00000052474
tipin
timeless interacting protein
chr25_+_4660639 0.43 ENSDART00000130299
deaf1
DEAF1 transcription factor
chr7_+_66884570 0.43 ENSDART00000082664
sbf2
SET binding factor 2
chr18_+_41560822 0.42 ENSDART00000158503
baz1b
bromodomain adjacent to zinc finger domain, 1B
chr24_+_39656834 0.42 ENSDART00000133942
ENSDART00000148089
ENSDART00000145075
stub1
STIP1 homology and U-Box containing protein 1
chr4_-_16883051 0.41 ENSDART00000124627
strap
serine/threonine kinase receptor associated protein
chr2_-_6292510 0.41 ENSDART00000092182
ppm1la
protein phosphatase, Mg2+/Mn2+ dependent, 1La
chr23_-_32162810 0.41 ENSDART00000155905
nr4a1
nuclear receptor subfamily 4, group A, member 1
chr8_+_16758304 0.40 ENSDART00000133514
elovl7a
ELOVL fatty acid elongase 7a
chr25_-_25142387 0.40 ENSDART00000031814
tsg101a
tumor susceptibility 101a
chr8_-_49701904 0.40 ENSDART00000142115
frmd3
FERM domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of foxn1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0030237 female sex determination(GO:0030237)
0.4 1.5 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.4 1.1 GO:0031645 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.3 1.4 GO:0070987 error-free translesion synthesis(GO:0070987)
0.3 0.9 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.3 0.8 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.2 1.2 GO:0023041 neuronal signal transduction(GO:0023041)
0.2 2.1 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.2 0.9 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.2 1.0 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.2 1.0 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.2 1.9 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.2 1.4 GO:0090660 cerebrospinal fluid circulation(GO:0090660) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.2 0.5 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.2 1.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.2 0.5 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.2 1.6 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.2 0.8 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.7 GO:0046329 negative regulation of JUN kinase activity(GO:0043508) negative regulation of JNK cascade(GO:0046329)
0.1 0.4 GO:0005997 xylulose metabolic process(GO:0005997)
0.1 1.9 GO:0090279 regulation of calcium ion import(GO:0090279)
0.1 1.8 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.9 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.1 0.4 GO:0043111 replication fork arrest(GO:0043111)
0.1 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 1.3 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 1.0 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 0.4 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.7 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 0.6 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.3 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 1.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 2.1 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.5 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 0.8 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 1.9 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.1 0.8 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.5 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.1 0.4 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.1 0.2 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.1 1.7 GO:0006828 manganese ion transport(GO:0006828)
0.1 1.0 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 1.5 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.1 0.9 GO:2000651 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.9 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1 1.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.6 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 1.1 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 1.3 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.0 1.4 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.4 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:0086013 membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:1990564 IRE1-mediated unfolded protein response(GO:0036498) negative regulation of response to endoplasmic reticulum stress(GO:1903573) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.3 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.8 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 1.2 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.5 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:1903358 regulation of Golgi organization(GO:1903358)
0.0 1.8 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.6 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 1.1 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.4 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:1901546 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.0 0.7 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.7 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.3 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 1.1 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.8 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.5 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 1.0 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.8 GO:0038034 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 1.7 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.8 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.6 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 1.1 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.8 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0017145 stem cell division(GO:0017145)
0.0 0.3 GO:0031060 regulation of histone methylation(GO:0031060)
0.0 0.5 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.2 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 0.1 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.0 1.0 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.4 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 1.8 GO:0006865 amino acid transport(GO:0006865)
0.0 0.7 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.4 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 2.2 GO:0006936 muscle contraction(GO:0006936)
0.0 1.2 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.9 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.6 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0097361 CIA complex(GO:0097361)
0.3 1.0 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.2 1.6 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 1.5 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.2 0.6 GO:0097255 R2TP complex(GO:0097255)
0.1 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 1.0 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.7 GO:0016234 inclusion body(GO:0016234) Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 1.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.9 GO:0032300 mismatch repair complex(GO:0032300)
0.1 0.4 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.9 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 1.0 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.7 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.1 1.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 1.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 1.2 GO:0005844 polysome(GO:0005844)
0.0 2.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.0 0.5 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 0.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.7 GO:0030686 90S preribosome(GO:0030686)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.8 GO:0005930 axoneme(GO:0005930)
0.0 1.2 GO:0005643 nuclear pore(GO:0005643)
0.0 0.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 1.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.4 3.0 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.4 1.5 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.3 1.3 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.3 1.9 GO:0070698 type I activin receptor binding(GO:0070698)
0.2 1.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 0.7 GO:0052855 ATP-dependent NAD(P)H-hydrate dehydratase activity(GO:0047453) ADP-dependent NAD(P)H-hydrate dehydratase activity(GO:0052855)
0.2 0.9 GO:0032135 DNA insertion or deletion binding(GO:0032135)
0.2 1.7 GO:0016530 metallochaperone activity(GO:0016530)
0.2 1.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.2 0.7 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 1.8 GO:0035804 structural constituent of egg coat(GO:0035804)
0.2 1.6 GO:0035198 miRNA binding(GO:0035198)
0.1 1.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.3 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.1 1.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 1.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 1.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 0.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 1.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 2.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.6 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 1.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.8 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 1.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.5 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 2.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.4 GO:0035173 histone kinase activity(GO:0035173)
0.1 1.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.9 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 0.2 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.1 0.8 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 2.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.8 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.0 0.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 1.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.3 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.7 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.6 GO:0048038 quinone binding(GO:0048038)
0.0 0.4 GO:0030544 Hsp70 protein binding(GO:0030544) Hsp90 protein binding(GO:0051879)
0.0 0.6 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 1.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 1.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.5 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.4 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.9 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 2.1 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 1.0 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 1.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.8 GO:0005178 integrin binding(GO:0005178)
0.0 0.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 1.2 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.0 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 0.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.5 PID MYC PATHWAY C-MYC pathway
0.0 0.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.6 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.1 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.6 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.8 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 1.5 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.8 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.2 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 1.4 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE