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PRJNA195909:zebrafish embryo and larva development

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Results for gsx2+pnx

Z-value: 1.92

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Transcription factors associated with gsx2+pnx

Gene Symbol Gene ID Gene Info
pnx
ENSDARG00000025899 posterior neuron-specific homeobox
gsx2
ENSDARG00000043322 GS homeobox 2
gsx2
ENSDARG00000116417 GS homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gsx2dr11_v1_chr20_-_22484621_224846210.853.9e-03Click!
pnxdr11_v1_chr10_+_2799285_27992850.058.9e-01Click!

Activity profile of gsx2+pnx motif

Sorted Z-values of gsx2+pnx motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22310919 7.17 ENSDART00000108719
crygm2d10
crystallin, gamma M2d10
chr25_+_31277415 5.41 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr21_+_26390549 4.22 ENSDART00000185643
tmsb
thymosin, beta
chr20_+_26966725 3.77 ENSDART00000029781
ahsa1a
AHA1, activator of heat shock protein ATPase homolog 1a
chr25_+_31276842 3.40 ENSDART00000187238
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr14_-_4145594 3.16 ENSDART00000077348
casp3b
caspase 3, apoptosis-related cysteine peptidase b
chr25_+_29160102 2.99 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr15_-_12011390 2.87 ENSDART00000187403
si:dkey-202l22.6
si:dkey-202l22.6
chr16_+_31804590 2.72 ENSDART00000167321
wnt4b
wingless-type MMTV integration site family, member 4b
chr11_+_38280454 2.69 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr23_+_20110086 2.58 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr15_+_23799461 2.57 ENSDART00000154885
si:ch211-167j9.4
si:ch211-167j9.4
chr2_+_55982300 2.55 ENSDART00000183903
nmrk2
nicotinamide riboside kinase 2
chr12_+_20352400 2.51 ENSDART00000066383
hbae5
hemoglobin, alpha embryonic 5
chr15_+_19646902 2.50 ENSDART00000179822
lim2.3
lens intrinsic membrane protein 2.3
chr7_-_48667056 2.49 ENSDART00000006378
cdkn1ca
cyclin-dependent kinase inhibitor 1Ca
chr21_-_5205617 2.22 ENSDART00000145554
ENSDART00000045284
rpl37
ribosomal protein L37
chr3_-_61217753 2.20 ENSDART00000182630
pvalb5
parvalbumin 5
chr17_+_23298928 2.20 ENSDART00000153652
zgc:165461
zgc:165461
chr21_+_6751405 2.19 ENSDART00000037265
ENSDART00000146371
olfm1b
olfactomedin 1b
chr1_-_59287410 2.19 ENSDART00000158011
ENSDART00000170580
col5a3b
collagen, type V, alpha 3b
chr21_+_6751760 2.15 ENSDART00000135914
olfm1b
olfactomedin 1b
chr5_+_51597677 2.06 ENSDART00000048210
ENSDART00000184797
ckmt2b
creatine kinase, mitochondrial 2b (sarcomeric)
chr7_-_24046999 2.05 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dhrs4
dehydrogenase/reductase (SDR family) member 4
chr25_+_31868268 2.04 ENSDART00000022325
parp16
poly (ADP-ribose) polymerase family, member 16
chr6_-_7720332 2.00 ENSDART00000135945
rpsa
ribosomal protein SA
chr8_+_29986265 1.94 ENSDART00000148258
ptch1
patched 1
chr15_-_21877726 1.93 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
zgc:162608
chr12_+_45677293 1.93 ENSDART00000152850
ENSDART00000153047
si:ch73-111m19.2
si:ch73-111m19.2
chr3_-_46817499 1.90 ENSDART00000013717
elavl3
ELAV like neuron-specific RNA binding protein 3
chr13_+_35339182 1.90 ENSDART00000019323
jag1b
jagged 1b
chr3_+_59784632 1.90 ENSDART00000084729
pecam1
platelet/endothelial cell adhesion molecule 1
chr14_+_11458044 1.87 ENSDART00000186425
si:ch211-153b23.5
si:ch211-153b23.5
chr1_+_127250 1.75 ENSDART00000003463
f7i
coagulation factor VIIi
chr11_-_472547 1.71 ENSDART00000005923
zgc:77375
zgc:77375
chr25_+_5035343 1.71 ENSDART00000011751
parvb
parvin, beta
chr20_+_535458 1.70 ENSDART00000152453
dse
dermatan sulfate epimerase
chr20_+_35382482 1.67 ENSDART00000135284
vsnl1a
visinin-like 1a
chr24_+_3307857 1.65 ENSDART00000106527
gyg1b
glycogenin 1b
chr13_+_255067 1.65 ENSDART00000102505
foxg1d
forkhead box G1d
chr11_+_44135351 1.65 ENSDART00000182914
FO704721.1

chr8_-_15129573 1.64 ENSDART00000142358
bcar3
BCAR3, NSP family adaptor protein
chr14_-_40390757 1.64 ENSDART00000149443
pcdh19
protocadherin 19
chr10_-_26744131 1.61 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fgf13b
fibroblast growth factor 13b
chr4_+_76575585 1.61 ENSDART00000131588
ms4a17a.11
membrane-spanning 4-domains, subfamily A, member 17A.11
chr19_-_2861444 1.60 ENSDART00000169053
clec3bb
C-type lectin domain family 3, member Bb
chr15_+_33865312 1.60 ENSDART00000166141
tekt1
tektin 1
chr5_-_19394440 1.60 ENSDART00000163771
foxn4
forkhead box N4
chr18_-_46256560 1.60 ENSDART00000171375
si:dkey-244a7.1
si:dkey-244a7.1
chr3_-_23643751 1.57 ENSDART00000078425
ENSDART00000140264
eve1
even-skipped-like1
chr1_-_50859053 1.56 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr15_-_22074315 1.53 ENSDART00000149830
drd2a
dopamine receptor D2a
chr3_-_18744511 1.52 ENSDART00000145539
zgc:113333
zgc:113333
chr3_-_50443607 1.52 ENSDART00000074036
rcvrna
recoverin a
chr18_+_48423973 1.52 ENSDART00000184233
ENSDART00000147074
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr13_+_30903816 1.51 ENSDART00000191727
ercc6
excision repair cross-complementation group 6
chr1_-_58036509 1.50 ENSDART00000081122
COLGALT1
si:ch211-114l13.7
chr1_-_58963395 1.50 ENSDART00000130415
CABZ01115881.1

chr1_+_50921266 1.49 ENSDART00000006538
otx2a
orthodenticle homeobox 2a
chr20_+_26880668 1.49 ENSDART00000077769
serpinb1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr9_-_22834860 1.47 ENSDART00000146486
neb
nebulin
chr21_-_22827548 1.47 ENSDART00000079161
angptl5
angiopoietin-like 5
chr15_+_1796313 1.46 ENSDART00000126253
fam124b
family with sequence similarity 124B
chr6_-_54815886 1.46 ENSDART00000180793
ENSDART00000007498
tnni1b
troponin I type 1b (skeletal, slow)
chr18_-_46258612 1.41 ENSDART00000153930
si:dkey-244a7.1
si:dkey-244a7.1
chr16_+_11834516 1.41 ENSDART00000146611
cxcr3.3
chemokine (C-X-C motif) receptor 3, tandem duplicate 3
chr3_-_61218272 1.41 ENSDART00000133091
ENSDART00000055068
pvalb5
parvalbumin 5
chr19_+_1831911 1.41 ENSDART00000166653
ptk2aa
protein tyrosine kinase 2aa
chr9_-_6372535 1.39 ENSDART00000149189
ecrg4a
esophageal cancer related gene 4a
chr16_-_42933332 1.39 ENSDART00000057305
thbs3a
thrombospondin 3a
chr7_-_27685365 1.38 ENSDART00000188342
calca
calcitonin/calcitonin-related polypeptide, alpha
chr11_+_26476153 1.37 ENSDART00000103507
unm_sa1614
un-named sa1614
chr21_-_37790727 1.35 ENSDART00000162907
gabrb4
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr16_-_31754102 1.35 ENSDART00000185043
ptpn6
protein tyrosine phosphatase, non-receptor type 6
chr3_+_29445473 1.35 ENSDART00000020381
grap2a
GRB2-related adaptor protein 2a
chr23_+_26979174 1.33 ENSDART00000018654
rnd1b
Rho family GTPase 1b
chr8_+_52619365 1.32 ENSDART00000162953
cyr61l2
cysteine-rich, angiogenic inducer, 61 like 2
chr10_+_32104305 1.31 ENSDART00000099880
wnt11r
wingless-type MMTV integration site family, member 11, related
chr16_+_41826584 1.29 ENSDART00000147523
si:dkey-199f5.6
si:dkey-199f5.6
chr7_-_30174882 1.28 ENSDART00000110409
frmd5
FERM domain containing 5
chr13_+_22479988 1.26 ENSDART00000188182
ENSDART00000192972
ENSDART00000178372
ldb3a
LIM domain binding 3a
chr23_+_19813677 1.25 ENSDART00000139192
ENSDART00000142308
emd
emerin (Emery-Dreifuss muscular dystrophy)
chr21_+_18997511 1.24 ENSDART00000145591
rpl17
ribosomal protein L17
chr10_+_37137464 1.22 ENSDART00000114909
cuedc1a
CUE domain containing 1a
chr15_-_36533322 1.22 ENSDART00000156466
ENSDART00000121755
si:dkey-262k9.4
si:dkey-262k9.4
chr24_+_22485710 1.20 ENSDART00000146058
si:dkey-40h20.1
si:dkey-40h20.1
chr2_+_6963296 1.19 ENSDART00000147146
ddr2b
discoidin domain receptor tyrosine kinase 2b
chr12_+_30265802 1.18 ENSDART00000182412
afap1l2
actin filament associated protein 1-like 2
chr20_-_9462433 1.18 ENSDART00000152674
ENSDART00000040557
zgc:101840
zgc:101840
chr19_-_31402429 1.18 ENSDART00000137292
tmem106bb
transmembrane protein 106Bb
chr3_+_18398876 1.17 ENSDART00000141100
ENSDART00000138107
rps2
ribosomal protein S2
chr15_-_4528326 1.16 ENSDART00000158122
ENSDART00000155619
ENSDART00000128602
tfdp2
transcription factor Dp-2
chr11_-_42554290 1.15 ENSDART00000130573
atp6ap1la
ATPase H+ transporting accessory protein 1 like a
chr4_+_21129752 1.14 ENSDART00000169764
syt1a
synaptotagmin Ia
chr4_+_22480169 1.14 ENSDART00000146272
ENSDART00000066904
ndufb2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr21_+_45841731 1.13 ENSDART00000038657
faxdc2
fatty acid hydroxylase domain containing 2
chr22_+_17205608 1.12 ENSDART00000181267
rab3b
RAB3B, member RAS oncogene family
chr11_-_30158191 1.11 ENSDART00000155278
ENSDART00000156121
scml2
Scm polycomb group protein like 2
chr1_+_52392511 1.11 ENSDART00000144025
si:ch211-217k17.8
si:ch211-217k17.8
chr11_-_40728380 1.10 ENSDART00000023745
ccdc114
coiled-coil domain containing 114
chr4_-_73756673 1.09 ENSDART00000174274
ENSDART00000192913
ENSDART00000113546
BX855614.4
si:dkey-262g12.14
zgc:171551

si:dkey-262g12.14
zgc:171551
chr20_-_14925281 1.09 ENSDART00000152641
dnm3a
dynamin 3a
chr3_-_60827402 1.08 ENSDART00000053494
anks4b
ankyrin repeat and sterile alpha motif domain containing 4B
chr15_-_35252522 1.07 ENSDART00000144153
ENSDART00000059195
mff
mitochondrial fission factor
chr3_-_38783951 1.06 ENSDART00000155518
znf281a
zinc finger protein 281a
chr3_+_30500968 1.05 ENSDART00000103447
si:dkey-13n23.3
si:dkey-13n23.3
chr24_-_38657683 1.05 ENSDART00000154843
si:ch1073-164k15.3
si:ch1073-164k15.3
chr5_+_40485503 1.05 ENSDART00000051055
ndufs4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase)
chr20_-_46362606 1.05 ENSDART00000153087
bmf2
BCL2 modifying factor 2
chr8_+_1766206 1.04 ENSDART00000021820
serpind1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr21_-_26490186 1.04 ENSDART00000009889
zgc:110540
zgc:110540
chr9_+_38372216 1.03 ENSDART00000141895
plcd4b
phospholipase C, delta 4b
chr7_+_38936132 1.03 ENSDART00000173945
creb3l1
cAMP responsive element binding protein 3-like 1
chr25_-_31953516 1.02 ENSDART00000110180
duox2
dual oxidase 2
chr18_-_48547564 1.02 ENSDART00000138607
kcnj1a.1
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr7_+_8456999 1.01 ENSDART00000172880
jac4
jacalin 4
chr14_-_14643190 1.01 ENSDART00000167119
znf185
zinc finger protein 185 with LIM domain
chr8_-_31107537 1.00 ENSDART00000098925
vgll4l
vestigial like 4 like
chr17_+_6452511 1.00 ENSDART00000064694
TATDN3
Danio rerio TatD DNase domain containing 3-like (LOC571912), mRNA.
chr15_-_12011202 0.98 ENSDART00000160427
ENSDART00000168715
si:dkey-202l22.6
si:dkey-202l22.6
chr14_-_33824329 0.98 ENSDART00000189271
ENSDART00000180458
vimr2
vimentin-related 2
chr20_-_13774826 0.97 ENSDART00000063831
opn8c
opsin 8, group member c
chr15_-_2632891 0.97 ENSDART00000081840
cldnj
claudin j
chr11_+_7264457 0.96 ENSDART00000154182
reep6
receptor accessory protein 6
chr8_-_23776399 0.96 ENSDART00000114800
INAVA
si:ch211-163l21.4
chr23_-_31512496 0.96 ENSDART00000158755
ENSDART00000143425
eya4
EYA transcriptional coactivator and phosphatase 4
chr11_-_41853874 0.95 ENSDART00000002556
mrto4
MRT4 homolog, ribosome maturation factor
chr15_+_5360407 0.95 ENSDART00000110420
or112-1
odorant receptor, family A, subfamily 112, member 1
chr23_+_28582865 0.93 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr19_+_43780970 0.93 ENSDART00000063870
rpl11
ribosomal protein L11
chr21_+_1381276 0.92 ENSDART00000192907
TCF4
transcription factor 4
chr14_+_5385855 0.92 ENSDART00000031508
lbx2
ladybird homeobox 2
chr7_+_69019851 0.91 ENSDART00000162891
CABZ01057488.1

chr19_-_38611814 0.91 ENSDART00000151958
col16a1
collagen, type XVI, alpha 1
chr4_+_58576146 0.90 ENSDART00000164911
si:ch211-212k5.4
si:ch211-212k5.4
chr24_+_6107901 0.90 ENSDART00000156419
si:ch211-37e10.2
si:ch211-37e10.2
chr1_+_7517454 0.88 ENSDART00000016139
lancl1
LanC antibiotic synthetase component C-like 1 (bacterial)
chr11_-_2131280 0.87 ENSDART00000008409
calcoco1b
calcium binding and coiled-coil domain 1b
chr4_+_47636303 0.87 ENSDART00000167272
ENSDART00000166961
BX324142.1

chr1_-_14332283 0.87 ENSDART00000090025
wfs1a
Wolfram syndrome 1a (wolframin)
chr4_+_72723304 0.86 ENSDART00000186791
ENSDART00000158902
ENSDART00000191925
rab3ip
RAB3A interacting protein (rabin3)
chr16_-_25568512 0.85 ENSDART00000149411
atxn1b
ataxin 1b
chr11_-_15296805 0.85 ENSDART00000124968
rpn2
ribophorin II
chr24_-_36680261 0.85 ENSDART00000059507
ccr10
chemokine (C-C motif) receptor 10
chr23_-_969844 0.84 ENSDART00000127037
cdh26.2
cadherin 26, tandem duplicate 2
chr13_-_40726865 0.83 ENSDART00000099847
st3gal7
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr14_-_7137808 0.83 ENSDART00000054803
trpt1
tRNA phosphotransferase 1
chr18_+_5137241 0.82 ENSDART00000159601
serpini1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr12_-_28363111 0.80 ENSDART00000016283
ENSDART00000164156
psmd11b
proteasome 26S subunit, non-ATPase 11b
chr21_+_45757317 0.79 ENSDART00000163152
h2afy
H2A histone family, member Y
chr4_-_45100253 0.79 ENSDART00000163870
si:dkey-51d8.3
si:dkey-51d8.3
chr24_-_6078222 0.79 ENSDART00000146830
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr4_-_77506362 0.79 ENSDART00000174387
ENSDART00000181181
CABZ01087415.1

chr23_-_44219902 0.79 ENSDART00000185874
zgc:158659
zgc:158659
chr7_+_30787903 0.78 ENSDART00000174000
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr14_+_30795559 0.77 ENSDART00000006132
cfl1
cofilin 1
chr24_-_37640705 0.77 ENSDART00000066583
zgc:112496
zgc:112496
chr3_-_61099004 0.77 ENSDART00000112043
cacng4b
calcium channel, voltage-dependent, gamma subunit 4b
chr22_-_12746539 0.76 ENSDART00000175374
plcd4a
phospholipase C, delta 4a
chr12_+_22580579 0.76 ENSDART00000171725
ENSDART00000192290
capgb
capping protein (actin filament), gelsolin-like b
chr19_-_5669122 0.75 ENSDART00000112211
si:ch211-264f5.2
si:ch211-264f5.2
chr9_-_5263947 0.74 ENSDART00000088342
cytip
cytohesin 1 interacting protein
chr3_-_30625219 0.74 ENSDART00000151698
syt3
synaptotagmin III
chr6_+_6924637 0.74 ENSDART00000065551
ENSDART00000151393
zak
sterile alpha motif and leucine zipper containing kinase AZK
chr7_-_71758307 0.74 ENSDART00000161067
ENSDART00000165253
myom1b
myomesin 1b
chr14_+_924876 0.73 ENSDART00000183908
myoz3a
myozenin 3a
chr22_-_8388678 0.73 ENSDART00000184389
CABZ01061498.1

chr20_-_14924858 0.72 ENSDART00000047039
dnm3a
dynamin 3a
chr24_-_31425799 0.72 ENSDART00000157998
cngb3.1
cyclic nucleotide gated channel beta 3, tandem duplicate 1
chr21_-_42097736 0.71 ENSDART00000100000
gabra1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr18_+_1154189 0.71 ENSDART00000135090
si:ch1073-75f15.2
si:ch1073-75f15.2
chr3_-_34084387 0.71 ENSDART00000155365
ighv4-3
immunoglobulin heavy variable 4-3
chr8_-_24803111 0.71 ENSDART00000186281
BX324132.3

chr20_-_35578435 0.70 ENSDART00000142444
adgrf6
adhesion G protein-coupled receptor F6
chr3_-_23407720 0.70 ENSDART00000155658
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr20_+_25225112 0.70 ENSDART00000153088
ENSDART00000127291
ENSDART00000130494
moxd1
monooxygenase, DBH-like 1
chr18_+_23408073 0.68 ENSDART00000136489
mctp2a
multiple C2 domains, transmembrane 2a
chr14_-_36320506 0.67 ENSDART00000074639
egf
epidermal growth factor
chr25_+_469855 0.67 ENSDART00000104717
rsl24d1
ribosomal L24 domain containing 1
chr3_-_58798377 0.66 ENSDART00000161248
si:ch73-281f12.4
si:ch73-281f12.4
chr2_+_33382648 0.65 ENSDART00000137207
ENSDART00000098831
slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr16_-_51288178 0.65 ENSDART00000079864
zgc:173729
zgc:173729
chr18_-_2433011 0.64 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr19_-_7495006 0.63 ENSDART00000148836
rfx5
regulatory factor X, 5
chr6_-_30954268 0.62 ENSDART00000154523
pde4ba
phosphodiesterase 4B, cAMP-specific a
chr15_-_2493771 0.62 ENSDART00000184906
neu4
sialidase 4
chr25_-_13839743 0.62 ENSDART00000158780
mapk8ip1a
mitogen-activated protein kinase 8 interacting protein 1a
chr5_+_1079423 0.61 ENSDART00000172231
si:zfos-128g4.2
si:zfos-128g4.2
chr23_+_40460333 0.60 ENSDART00000184658
soga3b
SOGA family member 3b
chr14_+_22591624 0.59 ENSDART00000108987
gfra4b
GDNF family receptor alpha 4b
chr19_-_657439 0.58 ENSDART00000167100
slc6a18
solute carrier family 6 (neutral amino acid transporter), member 18
chr5_-_69649044 0.57 ENSDART00000011192
ENSDART00000170885
eif2b1
eukaryotic translation initiation factor 2B, subunit 1 alpha
chr7_+_54642005 0.56 ENSDART00000171864
fgf19
fibroblast growth factor 19
chr18_+_11506561 0.56 ENSDART00000121647
PRMT8
protein arginine methyltransferase 8
chr11_-_21528056 0.55 ENSDART00000181626
srgap2
SLIT-ROBO Rho GTPase activating protein 2
chr24_+_11908833 0.54 ENSDART00000178622
fen1
flap structure-specific endonuclease 1
chr5_-_61624693 0.54 ENSDART00000141323
si:dkey-261j4.4
si:dkey-261j4.4
chr3_+_34919810 0.53 ENSDART00000055264
ca10b
carbonic anhydrase Xb
chr21_-_45076778 0.53 ENSDART00000181525
rapgef6
Rap guanine nucleotide exchange factor (GEF) 6
chr23_-_1658980 0.52 ENSDART00000186227
CU693481.1

Network of associatons between targets according to the STRING database.

First level regulatory network of gsx2+pnx

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.5 1.4 GO:0070314 G1 to G0 transition(GO:0070314)
0.4 1.2 GO:0032677 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.4 1.9 GO:0010872 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.4 2.5 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.3 3.8 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.3 1.7 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.3 0.3 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.3 1.4 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.3 1.6 GO:0035881 amacrine cell differentiation(GO:0035881)
0.3 13.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.3 0.8 GO:0030043 actin filament fragmentation(GO:0030043)
0.3 0.8 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.2 1.7 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.2 1.5 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.2 0.7 GO:0006589 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.2 0.7 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.2 1.9 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.2 1.5 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.2 1.0 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.2 0.9 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.2 3.2 GO:0030216 keratinocyte differentiation(GO:0030216)
0.2 0.6 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.2 2.1 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.2 0.9 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.7 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 1.5 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 0.3 GO:0046635 positive regulation of alpha-beta T cell activation(GO:0046635)
0.1 1.6 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.1 0.3 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 1.9 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.5 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.1 1.6 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 2.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 2.5 GO:0015671 oxygen transport(GO:0015671)
0.1 1.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.5 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.1 1.4 GO:0007172 signal complex assembly(GO:0007172)
0.1 1.0 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 1.4 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.3 GO:0060292 long term synaptic depression(GO:0060292)
0.1 1.7 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.5 GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) cellular response to virus(GO:0098586)
0.1 3.9 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 0.4 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 1.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.4 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 2.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 2.7 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.1 0.8 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 1.2 GO:0032418 lysosome localization(GO:0032418)
0.1 0.3 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.1 1.6 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 1.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 7.7 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 0.5 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 1.9 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 4.5 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.5 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 0.8 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.6 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.8 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 1.4 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.9 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 1.0 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 1.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.3 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 0.2 GO:1903828 negative regulation of cellular protein localization(GO:1903828)
0.0 3.0 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 0.4 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.3 GO:0033628 regulation of cell adhesion mediated by integrin(GO:0033628)
0.0 1.7 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 1.0 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.4 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 1.1 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.6 GO:0048854 brain morphogenesis(GO:0048854)
0.0 0.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.6 GO:0030282 bone mineralization(GO:0030282)
0.0 0.8 GO:0051014 actin filament severing(GO:0051014)
0.0 1.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.9 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.3 GO:0007608 sensory perception of smell(GO:0007608)
0.0 1.0 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 2.4 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.9 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.1 GO:0001774 microglial cell activation(GO:0001774)
0.0 0.4 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.3 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.0 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 1.2 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 1.0 GO:0007602 phototransduction(GO:0007602)
0.0 1.0 GO:0022900 electron transport chain(GO:0022900)
0.0 0.7 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 0.4 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.6 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 1.2 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.7 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.0 GO:0002369 T cell cytokine production(GO:0002369)
0.0 0.7 GO:0046328 regulation of JNK cascade(GO:0046328)
0.0 0.4 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.7 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 3.0 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742)
0.0 1.0 GO:0007601 visual perception(GO:0007601)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 13.3 GO:0005861 troponin complex(GO:0005861)
0.2 1.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 0.9 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.2 2.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 1.2 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 1.9 GO:0042627 chylomicron(GO:0042627)
0.1 1.9 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 2.3 GO:0044327 dendritic spine head(GO:0044327)
0.1 0.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 2.3 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 3.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.4 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 2.2 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.9 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 2.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 4.5 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.6 GO:0030426 growth cone(GO:0030426)
0.0 2.2 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.4 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.7 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.3 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 1.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 2.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0045095 keratin filament(GO:0045095)
0.0 1.6 GO:0031514 motile cilium(GO:0031514)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.9 GO:0016342 catenin complex(GO:0016342)
0.0 18.7 GO:0005615 extracellular space(GO:0005615)
0.0 3.3 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.3 GO:0031430 M band(GO:0031430)
0.0 1.4 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 0.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.0 GO:0004743 pyruvate kinase activity(GO:0004743)
0.5 1.9 GO:0097108 hedgehog family protein binding(GO:0097108)
0.5 1.4 GO:0031716 calcitonin receptor binding(GO:0031716)
0.4 1.9 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.4 2.5 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.3 1.7 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 2.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 1.0 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 0.7 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.2 4.2 GO:0003785 actin monomer binding(GO:0003785)
0.2 2.5 GO:0031720 haptoglobin binding(GO:0031720)
0.2 3.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 1.2 GO:0042169 SH2 domain binding(GO:0042169)
0.2 0.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 1.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 1.1 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.2 2.1 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 1.0 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 3.2 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1 1.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 0.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 1.4 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.1 9.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.3 GO:0072545 tyrosine binding(GO:0072545)
0.1 0.4 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.1 0.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.3 GO:0031530 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.1 1.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 2.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 2.0 GO:0043236 laminin binding(GO:0043236)
0.1 1.9 GO:0005112 Notch binding(GO:0005112)
0.1 1.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.7 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 2.8 GO:0005109 frizzled binding(GO:0005109)
0.1 2.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.2 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 2.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.3 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.4 GO:0031779 melanocortin receptor binding(GO:0031779)
0.1 2.0 GO:0051020 GTPase binding(GO:0051020)
0.1 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.1 2.3 GO:0019957 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.1 0.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.7 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.3 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 2.2 GO:0019843 rRNA binding(GO:0019843)
0.0 1.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 4.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 4.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.4 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 1.0 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.3 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 4.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.0 2.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.4 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.4 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.3 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 1.0 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.4 GO:0019838 growth factor binding(GO:0019838)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.4 GO:0008198 ferrous iron binding(GO:0008198)
0.0 13.3 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.0 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 4.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.7 GO:0016247 channel regulator activity(GO:0016247)
0.0 0.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 0.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.4 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 PID FGF PATHWAY FGF signaling pathway
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.2 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.9 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.1 1.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.8 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 0.6 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 7.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 3.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 0.8 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.7 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 2.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 1.7 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.8 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.6 REACTOME TRANSLATION Genes involved in Translation