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PRJNA195909:zebrafish embryo and larva development

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Results for hdx

Z-value: 1.21

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Transcription factors associated with hdx

Gene Symbol Gene ID Gene Info
hdx
ENSDARG00000079382 highly divergent homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hdxdr11_v1_chr14_-_6225336_6225336-0.058.9e-01Click!

Activity profile of hdx motif

Sorted Z-values of hdx motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_24382651 2.54 ENSDART00000123789
qdprb2
quinoid dihydropteridine reductase b2
chr21_-_2322102 1.87 ENSDART00000162867
zgc:66483
zgc:66483
chr9_-_12888082 1.68 ENSDART00000133135
ENSDART00000134415
si:ch211-167j6.3
si:ch211-167j6.3
chr21_-_7940043 1.58 ENSDART00000099733
ENSDART00000136671
f2rl1.1
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1
chr17_-_6618574 1.53 ENSDART00000184486
si:ch211-189e2.3
si:ch211-189e2.3
chr2_+_37295088 1.37 ENSDART00000056519
gpr160
G protein-coupled receptor 160
chr17_-_2596125 1.32 ENSDART00000175740
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr23_+_37579107 1.29 ENSDART00000169376
plekhg5b
pleckstrin homology domain containing, family G (with RhoGef domain) member 5b
chr3_-_3413669 1.27 ENSDART00000113517
ENSDART00000179861
ENSDART00000115331
zgc:171446
zgc:171446
chr17_-_6641535 1.26 ENSDART00000154540
ENSDART00000180384
si:ch211-189e2.3
si:ch211-189e2.3
chr10_-_36793412 1.23 ENSDART00000185966
dhrs13a.2
dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 2
chr16_-_26820634 1.18 ENSDART00000111156
pdp1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr1_-_8928841 1.13 ENSDART00000103652
grin2ab
glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b
chr6_-_2133737 1.09 ENSDART00000158535
vstm2l
V-set and transmembrane domain containing 2 like
chr5_-_38342992 1.07 ENSDART00000140337
mink1
misshapen-like kinase 1
chr15_-_26887028 1.06 ENSDART00000156292
si:dkey-243i1.1
si:dkey-243i1.1
chr5_+_27267186 1.04 ENSDART00000182238
ENSDART00000087857
unc5db
unc-5 netrin receptor Db
chr22_-_11054244 1.02 ENSDART00000105823
insrb
insulin receptor b
chr25_+_15997957 1.01 ENSDART00000140047
ppfibp2b
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr8_+_2773776 0.99 ENSDART00000156796
ENSDART00000154529
ENSDART00000155092
sh3glb2a
SH3-domain GRB2-like endophilin B2a
chr10_-_25570647 0.99 ENSDART00000134215
grik1a
glutamate receptor, ionotropic, kainate 1a
chr16_+_4181105 0.98 ENSDART00000180921
yrdc
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr14_+_34495216 0.96 ENSDART00000147756
wnt8a
wingless-type MMTV integration site family, member 8a
chr7_+_13684012 0.94 ENSDART00000056893
pdcd7
programmed cell death 7
chr2_+_34967210 0.93 ENSDART00000141796
astn1
astrotactin 1
chr2_+_45696743 0.91 ENSDART00000114225
ENSDART00000169279
CU467828.1

chr12_+_30788912 0.90 ENSDART00000160422
aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr23_-_478201 0.89 ENSDART00000140749
si:ch73-181d5.4
si:ch73-181d5.4
chr10_+_44373349 0.88 ENSDART00000172191
snrnp35
small nuclear ribonucleoprotein 35 (U11/U12)
chr2_+_5300405 0.88 ENSDART00000019925
GNB4
G protein subunit beta 4
chr13_+_31550185 0.88 ENSDART00000127843
ppm1aa
protein phosphatase, Mg2+/Mn2+ dependent, 1Aa
chr2_-_40890004 0.88 ENSDART00000191746
uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr19_-_3488860 0.87 ENSDART00000172520
hivep1
human immunodeficiency virus type I enhancer binding protein 1
chr6_-_18751696 0.87 ENSDART00000171537
tnrc6c2
trinucleotide repeat containing 6C2
chr22_-_23267893 0.85 ENSDART00000105613
si:dkey-121a9.3
si:dkey-121a9.3
chr23_+_19655301 0.84 ENSDART00000104441
ENSDART00000135269
abhd6b
abhydrolase domain containing 6b
chr15_+_42235449 0.84 ENSDART00000114801
ENSDART00000182053
SGPP2
sphingosine-1-phosphate phosphatase 2
chr24_-_27409599 0.83 ENSDART00000041770
ccl34b.3
chemokine (C-C motif) ligand 34b, duplicate 3
chr14_-_30490763 0.82 ENSDART00000193166
ENSDART00000183471
ENSDART00000087859
micu3b
mitochondrial calcium uptake family, member 3b
chr13_-_35459928 0.81 ENSDART00000144109
slx4ip
SLX4 interacting protein
chr6_+_54687495 0.80 ENSDART00000189514
smpd2b
sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase)
chr16_+_19029297 0.79 ENSDART00000115263
ENSDART00000114954
rapgef5b
Rap guanine nucleotide exchange factor (GEF) 5b
chr21_+_39336285 0.79 ENSDART00000139677
si:ch211-274p24.4
si:ch211-274p24.4
chr10_-_7734939 0.79 ENSDART00000075563
snx24
sorting nexin 24
chr3_-_27072179 0.78 ENSDART00000156556
atf7ip2
activating transcription factor 7 interacting protein 2
chr5_-_64454459 0.78 ENSDART00000172321
ENSDART00000168030
brd3b
bromodomain containing 3b
chr6_+_21005725 0.78 ENSDART00000041370
cx44.2
connexin 44.2
chr5_+_30596632 0.77 ENSDART00000051414
hinfp
histone H4 transcription factor
chr9_+_8364553 0.76 ENSDART00000190713
si:dkey-90l23.2
si:dkey-90l23.2
chr23_-_42810664 0.74 ENSDART00000102328
pfkfb2a
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr13_+_39297802 0.73 ENSDART00000133636
si:dkey-85a20.4
si:dkey-85a20.4
chr5_-_3885727 0.73 ENSDART00000143250
mlxipl
MLX interacting protein like
chr7_+_38962459 0.73 ENSDART00000173851
dgkza
diacylglycerol kinase, zeta a
chr2_-_40890264 0.72 ENSDART00000123886
uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr13_+_15580758 0.72 ENSDART00000087194
ENSDART00000013525
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr8_-_39884359 0.72 ENSDART00000131372
mlec
malectin
chr5_+_61941610 0.71 ENSDART00000168808
si:dkeyp-117b8.4
si:dkeyp-117b8.4
chr25_-_36261836 0.71 ENSDART00000179411
dus2
dihydrouridine synthase 2
chr10_-_18492617 0.71 ENSDART00000179936
ENSDART00000193799
ENSDART00000193198
si:dkey-28o19.1
si:dkey-28o19.1
chr16_-_35329803 0.71 ENSDART00000161729
ENSDART00000157700
ENSDART00000184584
ENSDART00000174713
ENSDART00000162518
ptprub
protein tyrosine phosphatase, receptor type, U, b
chr17_+_6536152 0.70 ENSDART00000062952
ENSDART00000121789
slc5a6b
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr17_-_6536466 0.69 ENSDART00000188735
cenpo
centromere protein O
chr5_+_63302660 0.68 ENSDART00000142131
si:ch73-376l24.2
si:ch73-376l24.2
chr3_+_16724614 0.68 ENSDART00000182135
gys1
glycogen synthase 1 (muscle)
chr8_-_4010887 0.68 ENSDART00000163678
mtmr3
myotubularin related protein 3
chr21_+_17051478 0.67 ENSDART00000047201
ENSDART00000161650
ENSDART00000167298
atp2a2a
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr4_+_26053044 0.67 ENSDART00000039877
SCYL2
si:ch211-244b2.1
chr25_+_33072676 0.67 ENSDART00000182885
ENSDART00000181516
tln2b
talin 2b
chr13_-_24257631 0.66 ENSDART00000146524
urb2
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr8_-_53044300 0.66 ENSDART00000191653
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr15_+_25683069 0.66 ENSDART00000148190
hic1
hypermethylated in cancer 1
chr16_+_3067134 0.66 ENSDART00000012048
cyb5r4
cytochrome b5 reductase 4
chr7_+_20030888 0.65 ENSDART00000192808
slc16a13
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr14_+_30398546 0.65 ENSDART00000053925
mtmr7a
myotubularin related protein 7a
chr22_-_5171362 0.65 ENSDART00000124889
tnfaip8l1
tumor necrosis factor, alpha-induced protein 8-like 1
chr10_-_32663759 0.65 ENSDART00000126727
atg101
autophagy related 101
chr1_+_59314675 0.65 ENSDART00000161872
ENSDART00000160658
ENSDART00000169792
ENSDART00000160735
parn
poly(A)-specific ribonuclease (deadenylation nuclease)
chr16_+_38820486 0.63 ENSDART00000131866
trhra
thyrotropin-releasing hormone receptor a
chr5_-_18007077 0.63 ENSDART00000129878
zdhhc8b
zinc finger, DHHC-type containing 8b
chr14_+_11290828 0.61 ENSDART00000184078
rlim
ring finger protein, LIM domain interacting
chr5_+_62356304 0.61 ENSDART00000148381
aspa
aspartoacylase
chr23_+_10805188 0.61 ENSDART00000035693
ppp4r2a
protein phosphatase 4, regulatory subunit 2a
chr14_-_3944017 0.61 ENSDART00000055817
si:ch73-49o8.1
si:ch73-49o8.1
chr11_+_5565082 0.61 ENSDART00000112590
ENSDART00000183207
si:ch73-40i7.5
si:ch73-40i7.5
chr1_+_54194801 0.60 ENSDART00000186802
CABZ01067150.1

chr16_+_23495600 0.60 ENSDART00000021092
snx27b
sorting nexin family member 27b
chr6_-_41021571 0.59 ENSDART00000103776
hdhd3
haloacid dehalogenase-like hydrolase domain containing 3
chr6_-_6295513 0.59 ENSDART00000092172
mtif2
mitochondrial translational initiation factor 2
chr5_+_1109098 0.58 ENSDART00000166268
LO017790.1

chr6_-_31323984 0.58 ENSDART00000183660
ENSDART00000184146
ENSDART00000180156
dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr19_+_4968947 0.58 ENSDART00000003634
ENSDART00000134808
stard3
StAR-related lipid transfer (START) domain containing 3
chr20_+_32552912 0.57 ENSDART00000009691
scml4
Scm polycomb group protein like 4
chr11_-_24532988 0.56 ENSDART00000067078
plekhg5a
pleckstrin homology domain containing, family G (with RhoGef domain) member 5a
chr7_+_22399669 0.56 ENSDART00000144375
fgf11a
fibroblast growth factor 11a
chr5_+_57210237 0.56 ENSDART00000167660
pja2
praja ring finger ubiquitin ligase 2
chr16_+_26735894 0.55 ENSDART00000191605
ENSDART00000185175
rad54b
RAD54 homolog B (S. cerevisiae)
chr19_+_19989380 0.55 ENSDART00000142841
osbpl3a
oxysterol binding protein-like 3a
chr13_+_33688474 0.54 ENSDART00000161465
CABZ01087953.1

chr1_-_29761086 0.53 ENSDART00000136760
alg11
asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase)
chr5_-_30620625 0.52 ENSDART00000098273
tcnl
transcobalamin like
chr23_+_43870886 0.51 ENSDART00000102658
ENSDART00000149088
nfxl1
nuclear transcription factor, X-box binding-like 1
chr2_+_31806602 0.51 ENSDART00000086608
ranbp9
RAN binding protein 9
chr12_+_26877381 0.51 ENSDART00000087329
znf438
zinc finger protein 438
chr5_+_50953240 0.51 ENSDART00000148501
ENSDART00000149892
ENSDART00000190312
col4a3bpa
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr22_+_1786230 0.51 ENSDART00000169318
ENSDART00000164948
znf1154
zinc finger protein 1154
chr22_+_35131890 0.51 ENSDART00000003303
ENSDART00000130581
rnf13
ring finger protein 13
chr13_+_35690023 0.51 ENSDART00000128865
ENSDART00000130050
psme4a
proteasome activator subunit 4a
chr22_+_11972786 0.51 ENSDART00000105788
mgat5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr16_-_26435431 0.49 ENSDART00000187526
megf8
multiple EGF-like-domains 8
chr6_-_16393491 0.49 ENSDART00000179312
agap1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr2_-_26720854 0.49 ENSDART00000148110
si:dkey-181m9.8
si:dkey-181m9.8
chr17_-_6536305 0.48 ENSDART00000154855
cenpo
centromere protein O
chr20_+_14789148 0.48 ENSDART00000164761
tmed5
transmembrane p24 trafficking protein 5
chr15_-_15968883 0.47 ENSDART00000166583
ENSDART00000154042
synrg
synergin, gamma
chr1_-_28950366 0.47 ENSDART00000110270
pwp2h
PWP2 periodic tryptophan protein homolog (yeast)
chr5_+_71924175 0.46 ENSDART00000115182
ENSDART00000170215
nup214
nucleoporin 214
chr6_-_55399214 0.46 ENSDART00000168367
ctsa
cathepsin A
chr16_+_27383717 0.46 ENSDART00000132329
ENSDART00000136256
stx17
syntaxin 17
chr10_+_43406796 0.46 ENSDART00000184337
ENSDART00000183034
ENSDART00000180623
ENSDART00000132486
rasa1b
RAS p21 protein activator (GTPase activating protein) 1b
chr9_-_23761087 0.45 ENSDART00000090486
si:ch211-219a4.6
si:ch211-219a4.6
chr7_-_48396193 0.45 ENSDART00000083555
sin3ab
SIN3 transcription regulator family member Ab
chr12_+_29173523 0.45 ENSDART00000153212
adgra1a
adhesion G protein-coupled receptor A1a
chr20_+_41756996 0.44 ENSDART00000186393
fam184a
family with sequence similarity 184, member A
chr22_-_9896180 0.43 ENSDART00000138343
znf990
zinc finger protein 990
chr25_-_15268443 0.42 ENSDART00000151827
ccdc73
coiled-coil domain containing 73
chr7_+_56889879 0.42 ENSDART00000039810
myo9aa
myosin IXAa
chr17_+_21546993 0.42 ENSDART00000182387
chst15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr24_-_11057305 0.42 ENSDART00000186494
asap1b
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1b
chr9_-_12886108 0.42 ENSDART00000177283
ankzf1
ankyrin repeat and zinc finger domain containing 1
chr15_-_6946286 0.42 ENSDART00000019330
ech1
enoyl CoA hydratase 1, peroxisomal
chr9_+_25840720 0.40 ENSDART00000024572
gtdc1
glycosyltransferase-like domain containing 1
chr25_+_34247353 0.40 ENSDART00000148914
bnip2
BCL2 interacting protein 2
chr20_-_25644131 0.40 ENSDART00000138997
si:dkeyp-117h8.4
si:dkeyp-117h8.4
chr11_+_44503774 0.39 ENSDART00000169295
ero1b
endoplasmic reticulum oxidoreductase beta
chr8_-_14067517 0.39 ENSDART00000140948
dedd
death effector domain containing
chr4_-_16706776 0.39 ENSDART00000079461
dennd5b
DENN/MADD domain containing 5B
chr3_-_53092509 0.39 ENSDART00000062081
lpar2a
lysophosphatidic acid receptor 2a
chr21_-_2565825 0.39 ENSDART00000169633
col4a3bpb
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein b
chr23_+_32029304 0.39 ENSDART00000185217
tpx2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr9_-_5318873 0.38 ENSDART00000129308
ACVR1C
activin A receptor type 1C
chr16_+_32082547 0.38 ENSDART00000190122
prpf31
PRP31 pre-mRNA processing factor 31 homolog (yeast)
chr20_+_50052116 0.37 ENSDART00000047212
cpsf2
cleavage and polyadenylation specific factor 2
chr4_-_13156971 0.37 ENSDART00000182164
grip1
glutamate receptor interacting protein 1
chr5_+_27421025 0.37 ENSDART00000098590
cyb561a3a
cytochrome b561 family, member A3a
chr1_-_23157583 0.37 ENSDART00000144208
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr2_+_25378457 0.37 ENSDART00000089108
fndc3ba
fibronectin type III domain containing 3Ba
chr1_-_23268569 0.37 ENSDART00000143948
rfc1
replication factor C (activator 1) 1
chr7_-_32875552 0.36 ENSDART00000132504
ano5b
anoctamin 5b
chr10_-_11203164 0.36 ENSDART00000040308
ptbp3
polypyrimidine tract binding protein 3
chr2_+_34767171 0.36 ENSDART00000145451
astn1
astrotactin 1
chr13_+_11828516 0.35 ENSDART00000110141
sufu
suppressor of fused homolog (Drosophila)
chr17_+_6535694 0.35 ENSDART00000191681
slc5a6b
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr19_-_10286228 0.35 ENSDART00000027316
cnot3b
CCR4-NOT transcription complex, subunit 3b
chr1_-_45614318 0.35 ENSDART00000149725
atf7ip
activating transcription factor 7 interacting protein
chr3_-_26906656 0.34 ENSDART00000156150
clec16a
C-type lectin domain containing 16A
chr22_-_8006342 0.34 ENSDART00000162028
sc:d217
sc:d217
chr5_+_1055042 0.33 ENSDART00000046781
rnf185
ring finger protein 185
chr5_-_6745442 0.33 ENSDART00000157402
ENSDART00000128684
ENSDART00000168698
ostf1
osteoclast stimulating factor 1
chr21_-_2958422 0.33 ENSDART00000174091
zgc:194215
zgc:194215
chr20_-_26841544 0.32 ENSDART00000088875
mylk4b
myosin light chain kinase family, member 4b
chr22_+_2100774 0.32 ENSDART00000106436
si:dkey-1b17.9
si:dkey-1b17.9
chr16_+_42471455 0.32 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr8_+_47099033 0.32 ENSDART00000142979
arhgef16
Rho guanine nucleotide exchange factor (GEF) 16
chr3_-_15886658 0.32 ENSDART00000113630
cramp1
cramped chromatin regulator homolog 1
chr3_-_33997763 0.32 ENSDART00000151461
ENSDART00000151307
ighz
immunoglobulin heavy constant zeta
chr12_-_26620728 0.31 ENSDART00000087067
hexdc
hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing
chr2_-_47923803 0.31 ENSDART00000056306
ftr24
finTRIM family, member 24
chr21_-_27272657 0.31 ENSDART00000040754
ENSDART00000175009
mark2a
MAP/microtubule affinity-regulating kinase 2a
chr4_-_16706941 0.31 ENSDART00000033053
ENSDART00000140510
ENSDART00000141119
dennd5b
DENN/MADD domain containing 5B
chr5_-_33825465 0.30 ENSDART00000110645
dab2ipb
DAB2 interacting protein b
chr19_-_35155722 0.30 ENSDART00000151924
macf1a
microtubule-actin crosslinking factor 1a
chr16_+_32729223 0.30 ENSDART00000125663
si:dkey-165n16.1
si:dkey-165n16.1
chr18_+_9810642 0.29 ENSDART00000143965
CACNA2D1
si:dkey-266j7.2
chr21_-_28439596 0.29 ENSDART00000089980
ENSDART00000132844
rasgrp2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr18_-_25276932 0.29 ENSDART00000076183
plin1
perilipin 1
chr3_-_11373435 0.29 ENSDART00000192654
AL935044.1

chr25_-_4313699 0.28 ENSDART00000154038
syt7a
synaptotagmin VIIa
chr15_-_8177919 0.28 ENSDART00000101463
bach1a
BTB and CNC homology 1, basic leucine zipper transcription factor 1 a
chr10_-_8197049 0.28 ENSDART00000129467
dhx29
DEAH (Asp-Glu-Ala-His) box polypeptide 29
chr12_+_23912074 0.27 ENSDART00000152864
svila
supervillin a
chr8_+_53120278 0.25 ENSDART00000125232
nr2c2
nuclear receptor subfamily 2, group C, member 2
chr20_+_36682051 0.24 ENSDART00000130513
ncoa1
nuclear receptor coactivator 1
chr20_+_19562383 0.24 ENSDART00000103798
nme6
NME/NM23 nucleoside diphosphate kinase 6
chr3_+_35298078 0.24 ENSDART00000110126
cacng3b
calcium channel, voltage-dependent, gamma subunit 3b
chr11_+_42600731 0.23 ENSDART00000182753
ENSDART00000192028
ENSDART00000085868
appl1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr4_-_25515154 0.23 ENSDART00000186524
rbm17
RNA binding motif protein 17
chr6_+_8652310 0.23 ENSDART00000105098
usp40
ubiquitin specific peptidase 40
chr11_-_18557277 0.22 ENSDART00000103950
dido1
death inducer-obliterator 1
chr3_-_26806032 0.22 ENSDART00000143710
pigq
phosphatidylinositol glycan anchor biosynthesis, class Q
chr4_-_8040436 0.22 ENSDART00000113033
si:ch211-240l19.6
si:ch211-240l19.6
chr19_+_26424734 0.22 ENSDART00000187402
npr1a
natriuretic peptide receptor 1a
chr5_+_72194444 0.22 ENSDART00000165436
ddx54
DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
chr3_-_25492361 0.21 ENSDART00000147322
ENSDART00000055473
grb2b
growth factor receptor-bound protein 2b
chr7_+_20031202 0.20 ENSDART00000052904
slc16a13
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr11_+_8152872 0.20 ENSDART00000091638
ENSDART00000138057
ENSDART00000166379
samd13
sterile alpha motif domain containing 13
chr25_+_388258 0.20 ENSDART00000166834
rfx7b
regulatory factor X7b
chr25_-_18778356 0.20 ENSDART00000111425
fbxl13
F-box and leucine-rich repeat protein 13
chr21_-_22715297 0.19 ENSDART00000065548
c1qb
complement component 1, q subcomponent, B chain
chr1_-_59313465 0.19 ENSDART00000158067
ENSDART00000159419
txndc11
thioredoxin domain containing 11
chr5_+_25680845 0.18 ENSDART00000139701
ENSDART00000009952
zfand5a
zinc finger, AN1-type domain 5a

Network of associatons between targets according to the STRING database.

First level regulatory network of hdx

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0021512 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.3 1.2 GO:1904184 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.3 1.0 GO:0051182 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.3 2.5 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.2 1.6 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 1.9 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 0.6 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.9 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 1.0 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 1.0 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.4 GO:1900181 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.1 0.5 GO:0035093 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.4 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.1 0.4 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 1.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 1.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 1.0 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 1.1 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 1.0 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.7 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 0.9 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 1.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.3 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.0 0.2 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 1.0 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.3 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.0 1.1 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.1 GO:1902592 virion assembly(GO:0019068) virus maturation(GO:0019075) multi-organism membrane organization(GO:0044803) viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.0 0.9 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.8 GO:0006684 sphingomyelin metabolic process(GO:0006684)
0.0 0.4 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.5 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 1.1 GO:0007099 centriole replication(GO:0007099)
0.0 0.6 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.9 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.0 0.5 GO:0070654 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.0 0.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461) vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.0 0.8 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.3 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.4 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:0046902 regulation of mitochondrial membrane permeability(GO:0046902)
0.0 0.3 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 1.1 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.8 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.7 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.4 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.1 GO:0030728 ovulation(GO:0030728)
0.0 0.4 GO:0001757 somite specification(GO:0001757)
0.0 0.6 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.5 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.6 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 0.7 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.1 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 1.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.2 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.7 GO:0006400 tRNA modification(GO:0006400)
0.0 0.7 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 1.0 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.4 GO:0019319 hexose biosynthetic process(GO:0019319)
0.0 0.5 GO:0006958 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 1.4 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.6 GO:0030301 cholesterol transport(GO:0030301)
0.0 0.5 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.7 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 0.2 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.5 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 1.1 GO:0097190 apoptotic signaling pathway(GO:0097190)
0.0 0.2 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.9 GO:0015718 monocarboxylic acid transport(GO:0015718)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0031511 Mis6-Sim4 complex(GO:0031511)
0.3 1.0 GO:0097189 apoptotic body(GO:0097189)
0.2 1.0 GO:0005899 insulin receptor complex(GO:0005899)
0.2 0.6 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.4 GO:0005880 nuclear microtubule(GO:0005880)
0.1 0.4 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.1 1.0 GO:1990246 uniplex complex(GO:1990246)
0.1 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.6 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 0.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 1.1 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.5 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.0 0.4 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.5 GO:0030130 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 2.1 GO:0030139 endocytic vesicle(GO:0030139)
0.0 1.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.9 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.4 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.0 GO:0048786 presynaptic active zone(GO:0048786)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0070404 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.3 1.6 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.3 1.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3 1.0 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 1.0 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.2 1.6 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 0.9 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.2 0.5 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.2 0.7 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.2 0.6 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 1.3 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.6 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.1 1.0 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.6 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.2 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.5 GO:0016504 peptidase activator activity(GO:0016504)
0.0 1.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.7 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.4 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 1.3 GO:0017069 snRNA binding(GO:0017069)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.1 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 1.0 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.0 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 0.8 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0034632 retinol transporter activity(GO:0034632)
0.0 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.9 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.5 GO:0030276 clathrin binding(GO:0030276)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.4 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.4 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.7 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 0.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.9 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.1 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.8 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.7 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex