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PRJNA195909:zebrafish embryo and larva development

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Results for hnf4a+hnf4b

Z-value: 1.11

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Transcription factors associated with hnf4a+hnf4b

Gene Symbol Gene ID Gene Info
hnf4a
ENSDARG00000021494 hepatocyte nuclear factor 4, alpha
hnf4b
ENSDARG00000104742 hepatic nuclear factor 4, beta
hnf4a
ENSDARG00000112985 hepatocyte nuclear factor 4, alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CABZ01057488.1dr11_v1_chr7_+_69019851_690198510.491.8e-01Click!
hnf4adr11_v1_chr23_+_25856541_258566410.324.0e-01Click!

Activity profile of hnf4a+hnf4b motif

Sorted Z-values of hnf4a+hnf4b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_23913943 3.87 ENSDART00000175404
ENSDART00000129525
apoa4b.1
apolipoprotein A-IV b, tandem duplicate 1
chr2_-_5728843 2.09 ENSDART00000014020
sst2
somatostatin 2
chr3_-_31804481 1.85 ENSDART00000028270
gfap
glial fibrillary acidic protein
chr12_-_5120339 1.77 ENSDART00000168759
rbp4
retinol binding protein 4, plasma
chr12_-_5120175 1.66 ENSDART00000160729
rbp4
retinol binding protein 4, plasma
chr16_+_23947196 1.65 ENSDART00000103190
ENSDART00000132961
ENSDART00000147690
ENSDART00000142168
apoa4b.2
apolipoprotein A-IV b, tandem duplicate 2
chr25_+_21829777 1.63 ENSDART00000027393
ckmt1
creatine kinase, mitochondrial 1
chr11_+_30729745 1.58 ENSDART00000103270
slc22a7a
solute carrier family 22 (organic anion transporter), member 7a
chr16_+_23921610 1.45 ENSDART00000143855
apoa4b.3
apolipoprotein A-IV b, tandem duplicate 3
chr24_-_33703504 1.45 ENSDART00000079292
cavin4b
caveolae associated protein 4b
chr16_+_23921777 1.43 ENSDART00000163213
apoa4b.3
apolipoprotein A-IV b, tandem duplicate 3
chr2_+_30916188 1.39 ENSDART00000137012
myom1a
myomesin 1a (skelemin)
chr15_-_26552393 1.32 ENSDART00000150152
serpinf2b
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr20_+_1412193 1.21 ENSDART00000064419
leg1.1
liver-enriched gene 1, tandem duplicate 1
chr18_+_17611627 1.20 ENSDART00000046891
cetp
cholesteryl ester transfer protein, plasma
chr22_+_37888249 1.20 ENSDART00000076082
fetub
fetuin B
chr16_+_54875530 1.19 ENSDART00000149795
nr0b2a
nuclear receptor subfamily 0, group B, member 2a
chr24_-_17047918 1.12 ENSDART00000020204
msrb2
methionine sulfoxide reductase B2
chr17_-_30702411 1.08 ENSDART00000114358
zgc:194392
zgc:194392
chr23_-_45504991 1.08 ENSDART00000148761
col24a1
collagen type XXIV alpha 1
chr23_-_24488696 1.07 ENSDART00000155593
tmem82
transmembrane protein 82
chr2_-_42958113 1.06 ENSDART00000139945
oc90
otoconin 90
chr7_+_24115082 1.05 ENSDART00000182718
mrpl52
mitochondrial ribosomal protein L52
chr17_+_33767890 1.04 ENSDART00000193177
fut8a
fucosyltransferase 8a (alpha (1,6) fucosyltransferase)
chr11_+_11201096 1.04 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myom2a
myomesin 2a
chr20_+_2281933 1.04 ENSDART00000137579
si:ch73-18b11.2
si:ch73-18b11.2
chr8_-_30791266 1.03 ENSDART00000062220
gstt1a
glutathione S-transferase theta 1a
chr6_-_40429411 1.02 ENSDART00000156005
ENSDART00000156357
si:dkey-28n18.9
si:dkey-28n18.9
chr2_-_42958619 1.00 ENSDART00000144317
oc90
otoconin 90
chr23_+_23658474 1.00 ENSDART00000162838
agrn
agrin
chr2_+_24536762 0.99 ENSDART00000144149
angptl4
angiopoietin-like 4
chr13_+_28819768 0.96 ENSDART00000191401
ENSDART00000188895
ENSDART00000101653
CU639469.1

chr2_-_37956768 0.96 ENSDART00000034595
cbln10
cerebellin 10
chr1_+_53374454 0.95 ENSDART00000038807
ucp1
uncoupling protein 1
chr4_-_16451375 0.93 ENSDART00000192700
ENSDART00000128835
wu:fc23c09
wu:fc23c09
chr25_+_5288665 0.91 ENSDART00000169540
CABZ01039861.1

chr15_-_26552652 0.87 ENSDART00000152336
serpinf2b
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr9_-_1986014 0.86 ENSDART00000142842
hoxd12a
homeobox D12a
chr7_+_24114694 0.84 ENSDART00000127177
mrpl52
mitochondrial ribosomal protein L52
chr16_+_5251768 0.81 ENSDART00000144558
plecb
plectin b
chr24_+_20960216 0.81 ENSDART00000133008
si:ch211-161h7.8
si:ch211-161h7.8
chr4_+_69619 0.78 ENSDART00000164425
mansc1
MANSC domain containing 1
chr13_-_40726865 0.77 ENSDART00000099847
st3gal7
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr21_+_25236297 0.77 ENSDART00000112783
tmem45b
transmembrane protein 45B
chr11_+_30321116 0.76 ENSDART00000187921
ENSDART00000127075
ugt1b1
UDP glucuronosyltransferase 1 family, polypeptide B1
chr23_-_45705525 0.76 ENSDART00000148959
ednrab
endothelin receptor type Ab
chr1_+_17900306 0.74 ENSDART00000089480
cyp4v8
cytochrome P450, family 4, subfamily V, polypeptide 8
chr5_-_64168415 0.74 ENSDART00000048395
cmlc1
cardiac myosin light chain-1
chr2_+_3533117 0.72 ENSDART00000132572
gpt2l
glutamic pyruvate transaminase (alanine aminotransferase) 2, like
chr7_+_25920792 0.72 ENSDART00000026295
arrb2b
arrestin, beta 2b
chr4_+_11172964 0.71 ENSDART00000193598
ENSDART00000138661
tspan11
tetraspanin 11
chr5_-_20205075 0.71 ENSDART00000051611
dao.3
D-amino-acid oxidase, tandem duplicate 3
chr13_-_22843562 0.71 ENSDART00000142738
pbld
phenazine biosynthesis like protein domain containing
chr15_+_36309070 0.68 ENSDART00000157034
gmnc
geminin coiled-coil domain containing
chr10_+_21650828 0.67 ENSDART00000160754
pcdh1g1
protocadherin 1 gamma 1
chr1_-_46706639 0.67 ENSDART00000074519
kpna3
karyopherin alpha 3 (importin alpha 4)
chr11_+_37250839 0.67 ENSDART00000170209
il17rc
interleukin 17 receptor C
chr17_-_42213285 0.67 ENSDART00000140549
nkx2.2a
NK2 homeobox 2a
chr22_-_20126230 0.66 ENSDART00000138688
creb3l3a
cAMP responsive element binding protein 3-like 3a
chr20_+_1398564 0.65 ENSDART00000002242
leg1.2
liver-enriched gene 1, tandem duplicate 2
chr16_+_16968682 0.64 ENSDART00000111074
si:ch211-120k19.1
si:ch211-120k19.1
chr12_+_2446837 0.64 ENSDART00000112032
ARHGAP22
si:dkey-191m6.4
chr20_+_22666548 0.64 ENSDART00000147520
lnx1
ligand of numb-protein X 1
chr6_+_27624023 0.63 ENSDART00000147789
slco2a1
solute carrier organic anion transporter family, member 2A1
chr16_+_16969060 0.63 ENSDART00000182819
ENSDART00000191876
si:ch211-120k19.1
rpl18
si:ch211-120k19.1
ribosomal protein L18
chr8_+_13106760 0.63 ENSDART00000029308
itgb4
integrin, beta 4
chr21_+_41743493 0.61 ENSDART00000192669
ppp2r2bb
protein phosphatase 2, regulatory subunit B, beta b
chr5_+_8919698 0.61 ENSDART00000046440
agpat9l
1-acylglycerol-3-phosphate O-acyltransferase 9, like
chr17_+_20173882 0.61 ENSDART00000155379
si:ch211-248a14.8
si:ch211-248a14.8
chr13_+_21779975 0.61 ENSDART00000021556
si:ch211-51a6.2
si:ch211-51a6.2
chr11_+_8129536 0.61 ENSDART00000158112
ENSDART00000011183
prkacba
protein kinase, cAMP-dependent, catalytic, beta a
chr16_-_32013913 0.61 ENSDART00000030282
ENSDART00000138701
gstk1
glutathione S-transferase kappa 1
chr14_+_21107032 0.60 ENSDART00000138319
ENSDART00000139103
ENSDART00000184735
aldob
aldolase b, fructose-bisphosphate
chr7_+_31838320 0.60 ENSDART00000144679
ENSDART00000174217
ENSDART00000122506
mybpc3
myosin binding protein C, cardiac
chr8_+_1766206 0.59 ENSDART00000021820
serpind1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr25_-_3230187 0.56 ENSDART00000160545
cib1
calcium and integrin binding 1 (calmyrin)
chr21_-_30111134 0.55 ENSDART00000014223
slc23a1
solute carrier family 23 (ascorbic acid transporter), member 1
chr20_+_43379029 0.55 ENSDART00000142486
ENSDART00000186486
unc93a
unc-93 homolog A
chr5_+_52039067 0.55 ENSDART00000143276
setbp1
SET binding protein 1
chr17_-_17948587 0.54 ENSDART00000090447
hhipl1
HHIP-like 1
chr24_-_32150276 0.53 ENSDART00000166212
cubn
cubilin (intrinsic factor-cobalamin receptor)
chr13_+_28821841 0.53 ENSDART00000179900
CU639469.1

chr23_+_23119008 0.52 ENSDART00000132418
samd11
sterile alpha motif domain containing 11
chr7_+_31871830 0.52 ENSDART00000139899
mybpc3
myosin binding protein C, cardiac
chr18_-_34143189 0.52 ENSDART00000079341
plch1
phospholipase C, eta 1
chr14_+_9009600 0.51 ENSDART00000133904
si:ch211-274f20.2
si:ch211-274f20.2
chr5_-_44843738 0.50 ENSDART00000003926
fbp1a
fructose-1,6-bisphosphatase 1a
chr1_-_52292235 0.48 ENSDART00000132638
si:dkey-121b10.7
si:dkey-121b10.7
chr20_+_5106568 0.47 ENSDART00000028039
cyp46a1.1
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1
chr21_-_27443995 0.46 ENSDART00000003508
bfb
complement component bfb
chr16_-_17197546 0.46 ENSDART00000139939
ENSDART00000135146
ENSDART00000063800
ENSDART00000163606
gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr4_-_71110826 0.46 ENSDART00000167431
si:dkeyp-80d11.1
si:dkeyp-80d11.1
chr10_+_20128267 0.45 ENSDART00000064615
dmtn
dematin actin binding protein
chr7_-_20453661 0.45 ENSDART00000174001
ntn5
netrin 5
chr2_+_28453338 0.44 ENSDART00000020456
mmp15b
matrix metallopeptidase 15b
chr11_+_30296332 0.44 ENSDART00000192843
ugt1b7
UDP glucuronosyltransferase 1 family, polypeptide B7
chr3_-_50443607 0.44 ENSDART00000074036
rcvrna
recoverin a
chr12_-_6172154 0.43 ENSDART00000185434
a1cf
apobec1 complementation factor
chr10_-_322769 0.43 ENSDART00000165244
akt2l
v-akt murine thymoma viral oncogene homolog 2, like
chr7_-_26457208 0.42 ENSDART00000173519
zgc:172079
zgc:172079
chr3_-_3496738 0.42 ENSDART00000186849
CABZ01040998.1

chr15_+_19797918 0.41 ENSDART00000113314
si:ch211-229d2.5
si:ch211-229d2.5
chr2_-_10450784 0.39 ENSDART00000081196
scinlb
scinderin like b
chr24_-_1341543 0.39 ENSDART00000169341
nrp1a
neuropilin 1a
chr18_-_7400075 0.39 ENSDART00000101250
si:dkey-30c15.13
si:dkey-30c15.13
chr10_-_15919839 0.38 ENSDART00000065032
pip5k1ba
phosphatidylinositol-4-phosphate 5-kinase, type I, beta a
chr18_-_7399767 0.38 ENSDART00000181689
si:dkey-30c15.13
si:dkey-30c15.13
chr20_-_54462551 0.38 ENSDART00000171769
ENSDART00000169692
evlb
Enah/Vasp-like b
chr18_+_36037223 0.38 ENSDART00000144410
tmem91
transmembrane protein 91
chr2_-_47870649 0.37 ENSDART00000142854
ftr05
finTRIM family, member 5
chr6_+_53429228 0.37 ENSDART00000165067
abhd14b
abhydrolase domain containing 14B
chr21_-_37194365 0.37 ENSDART00000100286
fgfr4
fibroblast growth factor receptor 4
chr17_+_450956 0.37 ENSDART00000183022
ENSDART00000171386
zgc:194887
zgc:194887
chr23_+_2778813 0.37 ENSDART00000142621
top1
DNA topoisomerase I
chr13_+_50375800 0.37 ENSDART00000099537
cox5b2
cytochrome c oxidase subunit Vb 2
chr13_+_35746440 0.37 ENSDART00000187859
gpr75
G protein-coupled receptor 75
chr3_-_10312232 0.36 ENSDART00000081766
nog1
noggin 1
chr3_+_16762483 0.36 ENSDART00000132732
tmem86b
transmembrane protein 86B
chr2_+_3533458 0.35 ENSDART00000133007
gpt2l
glutamic pyruvate transaminase (alanine aminotransferase) 2, like
chr6_+_18298444 0.35 ENSDART00000166018
card14
caspase recruitment domain family, member 14
chr10_+_29266392 0.35 ENSDART00000153577
crebzf
CREB/ATF bZIP transcription factor
chr3_-_39363065 0.35 ENSDART00000155894
arhgap23a
Rho GTPase activating protein 23a
chr3_+_39099716 0.35 ENSDART00000083388
tmem98
transmembrane protein 98
chr3_-_58116314 0.35 ENSDART00000154901
si:ch211-256e16.6
si:ch211-256e16.6
chr12_+_2455429 0.34 ENSDART00000182929
ARHGAP22
si:dkey-191m6.4
chr4_-_53354589 0.33 ENSDART00000169031
si:dkey-250k10.4
si:dkey-250k10.4
chr22_-_21392748 0.33 ENSDART00000144648
ankrd24
ankyrin repeat domain 24
chr25_-_26758253 0.33 ENSDART00000123004
si:dkeyp-73b11.8
si:dkeyp-73b11.8
chr4_-_18315912 0.32 ENSDART00000135735
plxnc1
plexin C1
chr12_-_36260532 0.32 ENSDART00000022533
kcnj2a
potassium inwardly-rectifying channel, subfamily J, member 2a
chr4_+_38981587 0.31 ENSDART00000142713
si:dkey-66k12.3
si:dkey-66k12.3
chr5_-_23317477 0.30 ENSDART00000090171
nlgn3b
neuroligin 3b
chr15_-_24178893 0.30 ENSDART00000077980
pipox
pipecolic acid oxidase
chr2_-_56655769 0.30 ENSDART00000113589
gpx4b
glutathione peroxidase 4b
chr7_+_25036188 0.30 ENSDART00000163957
ENSDART00000169749
sb:cb1058
sb:cb1058
chr24_-_36727922 0.29 ENSDART00000135142
si:ch73-334d15.1
si:ch73-334d15.1
chr22_-_15671525 0.28 ENSDART00000080286
si:ch1073-396h14.1
si:ch1073-396h14.1
chr22_-_10774735 0.28 ENSDART00000081156
timm13
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr21_-_37194669 0.28 ENSDART00000192748
fgfr4
fibroblast growth factor receptor 4
chr14_+_24935131 0.27 ENSDART00000170871
ppargc1b
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr6_+_30091811 0.27 ENSDART00000088403
meltf
melanotransferrin
chr4_+_11375894 0.27 ENSDART00000190471
ENSDART00000143963
pcloa
piccolo presynaptic cytomatrix protein a
chr3_+_24190207 0.26 ENSDART00000034762
prr15la
proline rich 15-like a
chr9_-_38036984 0.26 ENSDART00000134574
hacd2
3-hydroxyacyl-CoA dehydratase 2
chr13_+_45980163 0.25 ENSDART00000074547
ENSDART00000005195
bsdc1
BSD domain containing 1
chr16_-_25606889 0.25 ENSDART00000077447
ENSDART00000131528
zgc:110410
zgc:110410
chr14_-_16379843 0.24 ENSDART00000090711
ltc4s
leukotriene C4 synthase
chr1_-_9641845 0.24 ENSDART00000121490
ENSDART00000159411
ugt5b2
ugt5b3
UDP glucuronosyltransferase 5 family, polypeptide B2
UDP glucuronosyltransferase 5 family, polypeptide B3
chr8_-_25329967 0.24 ENSDART00000139682
eps8l3b
EPS8-like 3b
chr13_-_37254777 0.24 ENSDART00000139734
syne2b
spectrin repeat containing, nuclear envelope 2b
chr17_+_1499238 0.24 ENSDART00000187561
LO018430.1

chr7_-_17416092 0.23 ENSDART00000043689
ENSDART00000170003
nitr3a
nitr3c
novel immune-type receptor 3a
novel immune-type receptor 3c
chr19_-_30524952 0.23 ENSDART00000103506
hpcal4
hippocalcin like 4
chr20_-_38446891 0.23 ENSDART00000192013
itpkb
inositol-trisphosphate 3-kinase B
chr2_-_44282796 0.23 ENSDART00000163040
ENSDART00000166923
ENSDART00000056372
ENSDART00000109251
ENSDART00000132682
mpz
myelin protein zero
chr18_+_45200043 0.23 ENSDART00000015786
large2
LARGE xylosyl- and glucuronyltransferase 2
chr2_-_37960688 0.23 ENSDART00000055565
cbln14
cerebellin 14
chr15_+_15403560 0.23 ENSDART00000049831
dhrs11b
dehydrogenase/reductase (SDR family) member 11b
chr8_-_979735 0.23 ENSDART00000149612
znf366
zinc finger protein 366
chr6_-_54290227 0.22 ENSDART00000050483
SPDEF
SAM pointed domain containing ETS transcription factor
chr10_+_26747755 0.21 ENSDART00000100329
f9b
coagulation factor IXb
chr24_+_35911020 0.21 ENSDART00000088480
abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr8_-_8698607 0.21 ENSDART00000046712
zgc:86609
zgc:86609
chr23_-_24493768 0.21 ENSDART00000135559
ENSDART00000046933
sult1st5
sulfotransferase family 1, cytosolic sulfotransferase 5
chr1_+_27112479 0.21 ENSDART00000128671
bnc2
basonuclin 2
chr22_+_16320076 0.20 ENSDART00000164161
osbpl1a
oxysterol binding protein-like 1A
chr11_-_30364847 0.20 ENSDART00000078387
pecr
peroxisomal trans-2-enoyl-CoA reductase
chr18_-_27858123 0.20 ENSDART00000142068
iqcg
IQ motif containing G
chr3_-_50139860 0.19 ENSDART00000101563
btr02
bloodthirsty-related gene family, member 2
chr18_+_31410652 0.19 ENSDART00000098504
def8
differentially expressed in FDCP 8 homolog (mouse)
chr12_-_44307963 0.19 ENSDART00000161009
si:ch73-329n5.1
si:ch73-329n5.1
chr8_+_6576940 0.19 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr23_-_3759692 0.19 ENSDART00000028885
hmga1a
high mobility group AT-hook 1a
chr1_-_37383741 0.19 ENSDART00000193155
ENSDART00000191887
ENSDART00000189077
scpp1
secretory calcium-binding phosphoprotein 1
chr23_-_3759345 0.18 ENSDART00000132205
ENSDART00000137707
ENSDART00000189382
hmga1a
high mobility group AT-hook 1a
chr10_+_17026870 0.18 ENSDART00000184529
ENSDART00000157480
CR855996.2

chr19_-_25005609 0.18 ENSDART00000151129
xkr8.2
XK, Kell blood group complex subunit-related family, member 8, tandem duplicate 2
chr11_+_33284837 0.18 ENSDART00000166239
ENSDART00000111412
nkpd1
NTPase, KAP family P-loop domain containing 1
chr1_-_37383539 0.18 ENSDART00000127579
scpp1
secretory calcium-binding phosphoprotein 1
chr22_+_15331214 0.18 ENSDART00000136566
sult3st4
sulfotransferase family 3, cytosolic sulfotransferase 4
chr4_-_67799941 0.17 ENSDART00000185830
si:ch211-66c13.1
si:ch211-66c13.1
chr11_+_14281100 0.17 ENSDART00000193664
ENSDART00000161597
si:ch211-262i1.3
si:ch211-262i1.3
chr8_+_30699429 0.17 ENSDART00000005345
upb1
ureidopropionase, beta
chr6_-_40722480 0.17 ENSDART00000188187
kbtbd12
kelch repeat and BTB (POZ) domain containing 12
chr22_+_16497670 0.16 ENSDART00000014330
ier5
immediate early response 5
chr6_+_27339962 0.16 ENSDART00000193726
klhl30
kelch-like family member 30
chr7_-_52417060 0.16 ENSDART00000148579
myzap
myocardial zonula adherens protein
chr6_-_49769100 0.16 ENSDART00000148853
si:dkey-249d8.1
si:dkey-249d8.1
chr6_+_28051978 0.15 ENSDART00000143218
si:ch73-194h10.2
si:ch73-194h10.2
chr6_-_43221581 0.15 ENSDART00000112239
si:dkey-178o16.4
si:dkey-178o16.4
chr3_+_25508247 0.15 ENSDART00000039448
mchr1b
melanin-concentrating hormone receptor 1b
chr9_-_9977827 0.14 ENSDART00000187315
ENSDART00000010246
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr14_+_33329420 0.14 ENSDART00000171090
ENSDART00000164062
sowahd
sosondowah ankyrin repeat domain family d
chr1_-_47431453 0.14 ENSDART00000101104
gja5b
gap junction protein, alpha 5b
chr3_-_23643751 0.13 ENSDART00000078425
ENSDART00000140264
eve1
even-skipped-like1
chr5_-_69940868 0.13 ENSDART00000185924
ENSDART00000097357
ugt2a4
UDP glucuronosyltransferase 2 family, polypeptide A4
chr1_-_21297748 0.13 ENSDART00000142109
npy1r
neuropeptide Y receptor Y1
chr2_-_44199722 0.13 ENSDART00000140633
ENSDART00000145728
sdhc
succinate dehydrogenase complex, subunit C, integral membrane protein
chr9_-_470038 0.13 ENSDART00000170338
ENSDART00000162054
si:dkey-11f4.16
si:dkey-11f4.16
chr16_+_32029090 0.13 ENSDART00000041054
tmc4
transmembrane channel-like 4

Network of associatons between targets according to the STRING database.

First level regulatory network of hnf4a+hnf4b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.4 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.4 1.2 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.3 1.0 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.3 1.1 GO:0030091 protein repair(GO:0030091)
0.2 0.7 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 1.1 GO:0003210 cardiac atrium formation(GO:0003210)
0.2 0.7 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 0.7 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.2 0.6 GO:0015882 L-ascorbic acid transport(GO:0015882)
0.2 1.5 GO:0033292 T-tubule organization(GO:0033292)
0.2 0.7 GO:1900120 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.2 1.1 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.2 0.7 GO:0046144 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.2 0.5 GO:0005986 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.2 2.5 GO:0071715 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.1 0.7 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.8 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.1 1.6 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 1.0 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.1 0.7 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 1.2 GO:1990402 embryonic liver development(GO:1990402)
0.1 1.0 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.4 GO:0007508 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.1 1.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.3 GO:0046440 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.1 0.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.2 GO:1903173 fatty alcohol metabolic process(GO:1903173)
0.1 1.0 GO:0036065 fucosylation(GO:0036065)
0.1 0.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 1.2 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.1 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.9 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.0 4.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.6 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.5 GO:0006707 steroid catabolic process(GO:0006706) cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.4 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.4 GO:0018198 peptidyl-cysteine modification(GO:0018198)
0.0 5.5 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.0 0.2 GO:0019482 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.4 GO:0042664 negative regulation of endodermal cell fate specification(GO:0042664)
0.0 0.4 GO:0016556 mRNA modification(GO:0016556)
0.0 0.3 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 1.2 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.3 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.1 GO:0006549 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.0 0.4 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.4 GO:0051923 sulfation(GO:0051923)
0.0 0.4 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.4 GO:0051014 actin filament severing(GO:0051014)
0.0 2.4 GO:0006936 muscle contraction(GO:0006936)
0.0 0.1 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.6 GO:0031638 zymogen activation(GO:0031638)
0.0 0.1 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.0 0.3 GO:0030497 fatty acid elongation(GO:0030497)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.1 2.4 GO:0031430 M band(GO:0031430)
0.1 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 1.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 1.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.5 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.3 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 1.9 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 0.2 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0005922 connexon complex(GO:0005922)
0.0 1.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.4 GO:0034632 retinol transporter activity(GO:0034632)
0.3 1.1 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.3 0.8 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.2 0.7 GO:0031701 angiotensin receptor binding(GO:0031701)
0.2 1.0 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.2 0.7 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.2 0.5 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 1.6 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 0.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.4 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.8 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 1.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.5 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.1 0.6 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 1.8 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 0.3 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 1.0 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 1.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.3 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 0.7 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 1.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.1 GO:0030273 melanin-concentrating hormone receptor activity(GO:0030273)
0.0 0.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.4 GO:0016803 ether hydrolase activity(GO:0016803)
0.0 1.0 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.7 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 2.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 1.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 3.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 1.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.3 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 2.1 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)
0.0 2.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.8 PID FGF PATHWAY FGF signaling pathway
0.0 0.6 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.7 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 0.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.9 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors