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PRJNA195909:zebrafish embryo and larva development

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Results for hoxa10b

Z-value: 0.60

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Transcription factors associated with hoxa10b

Gene Symbol Gene ID Gene Info
hoxa10b
ENSDARG00000031337 homeobox A10b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxa10bdr11_v1_chr16_+_20910186_20910186-0.881.6e-03Click!

Activity profile of hoxa10b motif

Sorted Z-values of hoxa10b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_9485939 1.21 ENSDART00000157814
micall2b
mical-like 2b
chr10_-_21545091 1.17 ENSDART00000029122
ENSDART00000132207
zgc:165539
zgc:165539
chr22_+_5574952 0.92 ENSDART00000171774
zgc:171566
zgc:171566
chr11_-_25257045 0.92 ENSDART00000130477
snai1a
snail family zinc finger 1a
chr7_+_1473929 0.90 ENSDART00000050687
lpcat4
lysophosphatidylcholine acyltransferase 4
chr15_-_43978141 0.84 ENSDART00000041249
chordc1a
cysteine and histidine-rich domain (CHORD) containing 1a
chr24_-_21090447 0.78 ENSDART00000136507
ENSDART00000140786
ENSDART00000184841
qtrt2
queuine tRNA-ribosyltransferase accessory subunit 2
chr17_+_43595692 0.72 ENSDART00000156271
cfap99
cilia and flagella associated protein 99
chr2_+_35733335 0.69 ENSDART00000113489
rasal2
RAS protein activator like 2
chr1_-_53468160 0.69 ENSDART00000143349
zgc:66455
zgc:66455
chr17_+_50701748 0.69 ENSDART00000191938
ENSDART00000183220
ENSDART00000049464
fermt2
fermitin family member 2
chr12_-_10512911 0.68 ENSDART00000124562
ENSDART00000106163
zgc:152977
zgc:152977
chr13_+_8892784 0.68 ENSDART00000075054
ENSDART00000143705
thada
thyroid adenoma associated
chr16_-_27566552 0.67 ENSDART00000142102
zgc:153215
zgc:153215
chr13_+_33462232 0.67 ENSDART00000177841
zgc:136302
zgc:136302
chr2_-_17115256 0.62 ENSDART00000190488
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr17_-_50062909 0.62 ENSDART00000075209
zgc:113886
zgc:113886
chr14_-_7409364 0.62 ENSDART00000036463
dnd1
DND microRNA-mediated repression inhibitor 1
chr16_-_44945224 0.61 ENSDART00000156921
ncam3
neural cell adhesion molecule 3
chr5_-_31856681 0.61 ENSDART00000187817
pkn3
protein kinase N3
chr10_+_40321067 0.60 ENSDART00000109816
gltpb
glycolipid transfer protein b
chr17_-_30652738 0.60 ENSDART00000154960
sh3yl1
SH3 and SYLF domain containing 1
chr13_-_25719628 0.60 ENSDART00000135383
si:dkey-192p21.6
si:dkey-192p21.6
chr21_+_43178831 0.59 ENSDART00000151512
aff4
AF4/FMR2 family, member 4
chr5_-_57723929 0.58 ENSDART00000144237
gig2p
grass carp reovirus (GCRV)-induced gene 2p
chr5_-_37881345 0.58 ENSDART00000084819
arhgap35b
Rho GTPase activating protein 35b
chr3_-_29910547 0.58 ENSDART00000151501
RUNDC1
si:dkey-151m15.5
chr5_-_57289872 0.58 ENSDART00000189893
ENSDART00000050957
fer
fer (fps/fes related) tyrosine kinase
chr12_-_18961289 0.57 ENSDART00000168405
ep300a
E1A binding protein p300 a
chr11_+_11303458 0.57 ENSDART00000162486
ENSDART00000160703
si:dkey-23f9.4
si:dkey-23f9.4
chr25_+_9013342 0.56 ENSDART00000154207
ENSDART00000153705
im:7145024
im:7145024
chr14_+_45028062 0.56 ENSDART00000184717
ENSDART00000185481
ATP8A1
ATPase phospholipid transporting 8A1
chr23_+_28092083 0.55 ENSDART00000053958
c1galt1a
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a
chr13_-_17860307 0.53 ENSDART00000135920
ENSDART00000054579
march8
membrane-associated ring finger (C3HC4) 8
chr10_+_6013076 0.52 ENSDART00000167613
ENSDART00000159216
hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr1_+_2321384 0.51 ENSDART00000157662
farp1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr24_+_10202718 0.51 ENSDART00000126668
pou6f2
POU class 6 homeobox 2
chr9_+_34232503 0.51 ENSDART00000132836
nxpe3
neurexophilin and PC-esterase domain family, member 3
chr5_-_31857345 0.50 ENSDART00000112546
pkn3
protein kinase N3
chr6_-_9282080 0.50 ENSDART00000159506
ccdc14
coiled-coil domain containing 14
chr25_+_3549841 0.49 ENSDART00000164030
ccdc77
coiled-coil domain containing 77
chr20_-_27190393 0.49 ENSDART00000149024
btbd7
BTB (POZ) domain containing 7
chr11_+_31730680 0.47 ENSDART00000145497
diaph3
diaphanous-related formin 3
chr22_+_23430688 0.46 ENSDART00000160457
dennd1b
DENN/MADD domain containing 1B
chr24_-_23784701 0.46 ENSDART00000090368
sgk3
serum/glucocorticoid regulated kinase family, member 3
chr14_-_50028428 0.45 ENSDART00000163543
ENSDART00000168510
abhd18
abhydrolase domain containing 18
chr12_-_18961491 0.45 ENSDART00000172574
ep300a
E1A binding protein p300 a
chr2_-_10877765 0.44 ENSDART00000100607
cdc7
cell division cycle 7 homolog (S. cerevisiae)
chr2_+_49457449 0.44 ENSDART00000185470
sh3gl1a
SH3-domain GRB2-like 1a
chr10_+_15340768 0.44 ENSDART00000046274
ENSDART00000168909
trappc13
trafficking protein particle complex 13
chr12_-_4243268 0.44 ENSDART00000131275
zgc:92313
zgc:92313
chr10_-_20588787 0.43 ENSDART00000138045
ENSDART00000181885
ENSDART00000091115
nsd3
nuclear receptor binding SET domain protein 3
chr8_+_2656231 0.43 ENSDART00000160833
fam102aa
family with sequence similarity 102, member Aa
chr18_-_39288894 0.43 ENSDART00000186216
mapk6
mitogen-activated protein kinase 6
chr21_-_14830353 0.43 ENSDART00000134687
pus1
pseudouridylate synthase 1
chr13_-_27354003 0.42 ENSDART00000101479
ENSDART00000044652
ddx43
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
chr22_+_15959844 0.42 ENSDART00000182201
stil
scl/tal1 interrupting locus
chr15_+_29727799 0.42 ENSDART00000182006
zgc:153372
zgc:153372
chr1_-_14506759 0.41 ENSDART00000057044
si:dkey-194g4.1
si:dkey-194g4.1
chr23_+_45200481 0.40 ENSDART00000004357
ENSDART00000111126
ENSDART00000193560
ENSDART00000190476
psip1b
PC4 and SFRS1 interacting protein 1b
chr5_+_20453874 0.40 ENSDART00000124545
ENSDART00000008402
sart3
squamous cell carcinoma antigen recognized by T cells 3
chr15_+_22390076 0.40 ENSDART00000183764
oafa
OAF homolog a (Drosophila)
chr5_-_23715861 0.40 ENSDART00000019992
gbgt1l1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr13_-_24717365 0.40 ENSDART00000137934
ENSDART00000003922
erlin1
ER lipid raft associated 1
chr1_-_8566567 0.39 ENSDART00000114613
ptcd1
pentatricopeptide repeat domain 1
chr11_-_25257595 0.39 ENSDART00000123567
snai1a
snail family zinc finger 1a
chr21_+_19334198 0.39 ENSDART00000147372
helq
helicase, POLQ like
chr13_+_15580758 0.39 ENSDART00000087194
ENSDART00000013525
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr6_-_7107868 0.39 ENSDART00000171123
nhej1
nonhomologous end-joining factor 1
chr13_-_24717618 0.38 ENSDART00000172156
erlin1
ER lipid raft associated 1
chr13_+_13945218 0.38 ENSDART00000089501
ENSDART00000142997
eif2ak3
eukaryotic translation initiation factor 2-alpha kinase 3
chr20_-_29499363 0.38 ENSDART00000152889
ENSDART00000153252
ENSDART00000170972
ENSDART00000166420
ENSDART00000163079
rrm2
ribonucleotide reductase M2 polypeptide
chr2_+_51818039 0.38 ENSDART00000170353
acvr2bb
activin A receptor type 2Bb
chr24_-_15159658 0.38 ENSDART00000142473
rttn
rotatin
chr2_-_40889465 0.38 ENSDART00000192631
ENSDART00000180824
uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr11_+_6010177 0.38 ENSDART00000170047
ENSDART00000022526
ENSDART00000161001
ENSDART00000188999
gtpbp3
GTP binding protein 3, mitochondrial
chr11_-_26362294 0.38 ENSDART00000184654
ENSDART00000115037
foxj3
forkhead box J3
chr18_-_7097403 0.37 ENSDART00000003748
cfap161
cilia and flagella associated protein 161
chr3_-_60589292 0.36 ENSDART00000157822
jmjd6
jumonji domain containing 6
chr10_-_31805923 0.36 ENSDART00000077785
vps26bl
vacuolar protein sorting 26 homolog B, like
chr19_+_40069524 0.36 ENSDART00000151365
ENSDART00000140926
zmym4
zinc finger, MYM-type 4
chr6_+_40554551 0.36 ENSDART00000017859
ENSDART00000155928
ddi2
DNA-damage inducible protein 2
chr1_-_55068941 0.35 ENSDART00000152143
ENSDART00000152590
peli1a
pellino E3 ubiquitin protein ligase 1a
chr14_-_899170 0.35 ENSDART00000165211
ENSDART00000031992
rgs14a
regulator of G protein signaling 14a
chr1_-_41374117 0.35 ENSDART00000074777
htt
huntingtin
chr22_-_12337781 0.35 ENSDART00000188357
ENSDART00000123574
zranb3
zinc finger, RAN-binding domain containing 3
chr22_+_2512154 0.35 ENSDART00000097363
zgc:173726
zgc:173726
chr15_-_1843831 0.34 ENSDART00000156718
ENSDART00000154175
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr2_-_40890004 0.34 ENSDART00000191746
uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr1_+_41596099 0.34 ENSDART00000111367
si:dkey-56e3.3
si:dkey-56e3.3
chr21_+_4313039 0.34 ENSDART00000141146
HTRA2 (1 of many)
si:dkey-84o3.4
chr23_+_20431140 0.33 ENSDART00000193950
slc35c2
solute carrier family 35 (GDP-fucose transporter), member C2
chr5_-_65121747 0.33 ENSDART00000165556
tor2a
torsin family 2, member A
chr2_-_37458527 0.33 ENSDART00000146820
si:dkey-57k2.7
si:dkey-57k2.7
chr2_+_49805892 0.33 ENSDART00000056248
wdr48b
WD repeat domain 48b
chr22_+_1953096 0.33 ENSDART00000166630
ENSDART00000186234
si:dkey-15h8.16
si:dkey-15h8.16
chr2_-_20715094 0.33 ENSDART00000155439
dusp12
dual specificity phosphatase 12
chr23_-_24253200 0.33 ENSDART00000114840
zbtb17
zinc finger and BTB domain containing 17
chr20_-_2641233 0.32 ENSDART00000145335
ENSDART00000133121
bub1
BUB1 mitotic checkpoint serine/threonine kinase
chr18_+_21951551 0.32 ENSDART00000146261
ranbp10
RAN binding protein 10
chr12_+_32368574 0.32 ENSDART00000086389
ANKFN1
si:ch211-277e21.2
chr7_+_15308219 0.32 ENSDART00000165683
mespba
mesoderm posterior ba
chr22_-_24818066 0.32 ENSDART00000143443
vtg6
vitellogenin 6
chr25_-_29074064 0.32 ENSDART00000165603
arid3b
AT rich interactive domain 3B (BRIGHT-like)
chr25_+_16080181 0.31 ENSDART00000061753
far1
fatty acyl CoA reductase 1
chr16_+_46401756 0.31 ENSDART00000147370
ENSDART00000144000
rpz2
rapunzel 2
chr1_-_12397258 0.31 ENSDART00000144596
sclt1
sodium channel and clathrin linker 1
chr7_+_55149001 0.31 ENSDART00000148642
cdh31
cadherin 31
chr19_+_7424347 0.31 ENSDART00000004622
sf3b4
splicing factor 3b, subunit 4
chr18_+_15876385 0.31 ENSDART00000142527
eea1
early endosome antigen 1
chr5_-_16405651 0.30 ENSDART00000163942
slc39a14
solute carrier family 39 (zinc transporter), member 14
chr10_-_15340362 0.30 ENSDART00000148119
ENSDART00000127277
ENSDART00000154037
ENSDART00000189109
pum3
pumilio RNA-binding family member 3
chr20_-_34768301 0.30 ENSDART00000142482
paqr8
progestin and adipoQ receptor family member VIII
chr19_-_47571797 0.30 ENSDART00000166180
ENSDART00000168134
rrm2
ribonucleotide reductase M2 polypeptide
chr13_-_8892514 0.30 ENSDART00000144553
plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr14_-_238931 0.30 ENSDART00000161122
bod1l1
biorientation of chromosomes in cell division 1-like 1
chr2_+_22409249 0.30 ENSDART00000182915
zgc:56628
zgc:56628
chr11_-_25461336 0.30 ENSDART00000014945
hcfc1a
host cell factor C1a
chr8_-_31416403 0.29 ENSDART00000098912
znf131
zinc finger protein 131
chr22_+_10606573 0.29 ENSDART00000192638
rad54l2
RAD54 like 2
chr17_-_25630822 0.29 ENSDART00000126201
ENSDART00000105503
ENSDART00000151878
rab3gap2
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr12_-_6551681 0.29 ENSDART00000145413
si:ch211-253p2.2
si:ch211-253p2.2
chr1_+_12394205 0.29 ENSDART00000138622
ENSDART00000136421
ENSDART00000139440
ENSDART00000184296
ENSDART00000008127
zgc:77739
zgc:77739
chr13_+_7575563 0.28 ENSDART00000146592
gbf1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr13_+_33268657 0.28 ENSDART00000002095
tmem39b
transmembrane protein 39B
chr13_+_1131748 0.28 ENSDART00000054318
wdr92
WD repeat domain 92
chr17_-_31212420 0.28 ENSDART00000086511
rpusd2
RNA pseudouridylate synthase domain containing 2
chr8_-_39952727 0.28 ENSDART00000181310
cabp1a
calcium binding protein 1a
chr15_-_1733235 0.27 ENSDART00000023153
ENSDART00000154668
rabgef1l
RAB guanine nucleotide exchange factor (GEF) 1, like
chr2_+_54086436 0.27 ENSDART00000174581
CU179656.1

chr17_+_17764979 0.27 ENSDART00000105013
alkbh1
alkB homolog 1, histone H2A dioxygenase
chr12_+_41348969 0.27 ENSDART00000171352
si:ch211-27e6.1
si:ch211-27e6.1
chr1_+_57371447 0.27 ENSDART00000152229
ENSDART00000181077
si:dkey-27j5.3
si:dkey-27j5.3
chr21_-_14878220 0.27 ENSDART00000131237
ulk1b
unc-51 like autophagy activating kinase 1
chr7_+_17907883 0.27 ENSDART00000147564
mta2
metastasis associated 1 family, member 2
chr1_-_49947482 0.27 ENSDART00000143398
sgms2
sphingomyelin synthase 2
chr12_+_33361948 0.27 ENSDART00000124982
fasn
fatty acid synthase
chr16_-_32671998 0.27 ENSDART00000161395
pnisr
PNN-interacting serine/arginine-rich protein
chr16_+_36126310 0.26 ENSDART00000166040
ENSDART00000189802
sh3bp5b
SH3-domain binding protein 5b (BTK-associated)
chr12_+_11352630 0.26 ENSDART00000129495
si:rp71-19m20.1
si:rp71-19m20.1
chr19_-_47571456 0.26 ENSDART00000158071
ENSDART00000165841
rrm2
ribonucleotide reductase M2 polypeptide
chr5_+_7279104 0.26 ENSDART00000190014
si:ch73-72b7.1
si:ch73-72b7.1
chr7_-_7692723 0.25 ENSDART00000183352
aadat
aminoadipate aminotransferase
chr23_-_36823932 0.25 ENSDART00000142305
hipk1a
homeodomain interacting protein kinase 1a
chr14_+_10625112 0.25 ENSDART00000143377
ENSDART00000136480
nup62l
nucleoporin 62 like
chr8_-_10947205 0.25 ENSDART00000164467
pqlc2
PQ loop repeat containing 2
chr12_+_23912074 0.25 ENSDART00000152864
svila
supervillin a
chr4_-_11053543 0.25 ENSDART00000067262
mettl25
methyltransferase like 25
chr8_-_18899427 0.24 ENSDART00000079840
rorca
RAR-related orphan receptor C a
chr12_-_11560794 0.24 ENSDART00000149098
ENSDART00000169975
plekha1b
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b
chr10_-_11840353 0.24 ENSDART00000127581
trim23
tripartite motif containing 23
chr13_+_29292011 0.24 ENSDART00000115023
parga
poly (ADP-ribose) glycohydrolase a
chr6_+_45692026 0.24 ENSDART00000164759
cntn4
contactin 4
chr10_+_2975974 0.24 ENSDART00000147918
zfyve16
zinc finger, FYVE domain containing 16
chr25_-_27633115 0.23 ENSDART00000131539
hyal6
hyaluronoglucosaminidase 6
chr11_+_12052791 0.23 ENSDART00000158479
si:ch211-156l18.8
si:ch211-156l18.8
chr4_+_23125689 0.23 ENSDART00000077854
mdm2
MDM2 oncogene, E3 ubiquitin protein ligase
chr10_-_33297864 0.23 ENSDART00000163360
PRDM15
PR/SET domain 15
chr12_-_16452200 0.23 ENSDART00000037601
rpp30
ribonuclease P/MRP 30 subunit
chr13_+_24717880 0.23 ENSDART00000147713
cfap43
cilia and flagella associated protein 43
chr16_+_20934353 0.22 ENSDART00000052660
skap2
src kinase associated phosphoprotein 2
chr3_+_60589157 0.22 ENSDART00000165367
mettl23
methyltransferase like 23
chr2_-_49627099 0.22 ENSDART00000083710
ENSDART00000147421
cactin
cactin
chr17_+_21760032 0.22 ENSDART00000190425
ikzf5
IKAROS family zinc finger 5
chr3_+_31093455 0.22 ENSDART00000153074
si:dkey-66i24.9
si:dkey-66i24.9
chr23_+_43718115 0.22 ENSDART00000149266
ENSDART00000149503
anapc10
anaphase promoting complex subunit 10
chr22_+_30195257 0.22 ENSDART00000027803
ENSDART00000172496
add3a
adducin 3 (gamma) a
chr24_+_14581864 0.22 ENSDART00000134536
thtpa
thiamine triphosphatase
chr1_-_13989643 0.22 ENSDART00000191046
elf2b
E74-like factor 2b (ets domain transcription factor)
chr5_+_24063046 0.22 ENSDART00000051548
ENSDART00000133355
ENSDART00000142268
gps2
G protein pathway suppressor 2
chr2_-_50272077 0.22 ENSDART00000127623
cul1a
cullin 1a
chr2_+_30960351 0.21 ENSDART00000141575
lpin2
lipin 2
chr25_+_3549401 0.21 ENSDART00000166312
ccdc77
coiled-coil domain containing 77
chr13_+_9559461 0.21 ENSDART00000047740
wdr32
WD repeat domain 32
chr23_-_14766902 0.21 ENSDART00000168113
gss
glutathione synthetase
chr5_+_27137473 0.21 ENSDART00000181833
unc5db
unc-5 netrin receptor Db
chr13_-_9070754 0.21 ENSDART00000143783
ENSDART00000102121
ENSDART00000140820
ENSDART00000184210
si:dkey-112g5.12
si:dkey-112g5.12
chr4_-_17353972 0.21 ENSDART00000041529
parpbp
PARP1 binding protein
chr16_+_31942527 0.20 ENSDART00000188334
ENSDART00000188643
ENSDART00000058496
phc1
polyhomeotic homolog 1
chr5_+_50913034 0.20 ENSDART00000149787
col4a3bpa
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr13_+_9468535 0.20 ENSDART00000135088
ENSDART00000164270
ENSDART00000099619
ENSDART00000164656
HTRA2 (1 of many)
si:dkey-265c15.6
chr3_+_26135502 0.20 ENSDART00000146979
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr11_-_5953636 0.20 ENSDART00000140960
ENSDART00000123601
dda1
DET1 and DDB1 associated 1
chr21_-_3007412 0.19 ENSDART00000190839
CKS2
zgc:86839
chr7_-_16582187 0.19 ENSDART00000131726
e2f8
E2F transcription factor 8
chr15_-_23908605 0.19 ENSDART00000185578
usp32
ubiquitin specific peptidase 32
chr22_-_20950448 0.19 ENSDART00000002029
fkbp8
FK506 binding protein 8
chr15_-_26931541 0.19 ENSDART00000027563
ccdc9
coiled-coil domain containing 9
chr2_-_30912922 0.19 ENSDART00000141669
myl12.2
myosin, light chain 12, genome duplicate 2
chr25_+_22571475 0.19 ENSDART00000161559
stra6
stimulated by retinoic acid 6
chr12_-_10476448 0.18 ENSDART00000106172
rac1a
Rac family small GTPase 1a
chr8_+_39795918 0.18 ENSDART00000143413
si:ch211-170d8.2
si:ch211-170d8.2
chr3_+_39579393 0.18 ENSDART00000055170
cln3
ceroid-lipofuscinosis, neuronal 3
chr8_-_11324143 0.18 ENSDART00000008215
pip5k1bb
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr19_+_27970292 0.18 ENSDART00000103887
ENSDART00000145549
med10
mediator complex subunit 10
chr15_-_23908779 0.18 ENSDART00000088808
usp32
ubiquitin specific peptidase 32
chr20_+_32552912 0.17 ENSDART00000009691
scml4
Scm polycomb group protein like 4
chr7_+_22691961 0.17 ENSDART00000041615
ugt5g1
UDP glucuronosyltransferase 5 family, polypeptide G1
chr14_+_22467672 0.17 ENSDART00000079409
ENSDART00000136597
nudt22
nudix (nucleoside diphosphate linked moiety X)-type motif 22
chr16_+_38337783 0.17 ENSDART00000135008
gabpb2b
GA binding protein transcription factor, beta subunit 2b

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa10b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.2 0.9 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 0.5 GO:1902767 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.1 0.6 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 0.4 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.1 0.6 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.5 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.6 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.1 0.3 GO:0033212 iron assimilation(GO:0033212)
0.1 0.5 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.4 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 0.6 GO:0035627 ceramide transport(GO:0035627)
0.1 0.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.4 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 0.4 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 1.3 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.8 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.2 GO:1905072 cardiac jelly development(GO:1905072)
0.1 0.7 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 0.3 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.1 0.3 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 0.2 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.2 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.0 0.3 GO:0001839 neural plate morphogenesis(GO:0001839)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.3 GO:0048478 replication fork protection(GO:0048478)
0.0 0.2 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.3 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.0 0.2 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.0 0.7 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:0048917 posterior lateral line ganglion development(GO:0048917)
0.0 0.2 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.0 0.5 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.2 GO:0071939 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.0 0.2 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.7 GO:0008354 germ cell migration(GO:0008354)
0.0 0.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 1.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.2 GO:0015809 arginine transport(GO:0015809)
0.0 0.1 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.0 0.4 GO:0030259 lipid glycosylation(GO:0030259)
0.0 1.2 GO:0036269 swimming behavior(GO:0036269)
0.0 0.7 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.8 GO:0051298 centrosome duplication(GO:0051298)
0.0 0.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.0 0.3 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0090199 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.1 GO:0007440 foregut morphogenesis(GO:0007440)
0.0 0.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.7 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.1 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.0 0.2 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.1 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0050779 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.0 0.1 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.8 GO:0006400 tRNA modification(GO:0006400)
0.0 0.1 GO:0060036 notochord cell vacuolation(GO:0060036)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.3 GO:2000404 regulation of T cell migration(GO:2000404)
0.0 0.6 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.5 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.4 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.5 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0 0.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.5 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.2 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.5 GO:0051016 barbed-end actin filament capping(GO:0051016)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0043073 germ cell nucleus(GO:0043073)
0.1 0.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.2 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 0.4 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 0.6 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.7 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.0 1.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.4 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 1.5 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 1.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.0 GO:0005657 replication fork(GO:0005657)
0.0 1.4 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.0 GO:0000123 histone acetyltransferase complex(GO:0000123)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 0.5 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.7 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 0.4 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.1 0.6 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.9 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.6 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.4 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 0.6 GO:1902388 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 0.3 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.1 0.4 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.3 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.1 0.2 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.1 0.4 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.9 GO:0008242 omega peptidase activity(GO:0008242)
0.1 0.7 GO:0043495 protein anchor(GO:0043495)
0.1 0.2 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.1 0.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.5 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 0.3 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 1.1 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.0 0.1 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.0 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0034632 retinol transporter activity(GO:0034632)
0.0 0.2 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.1 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.0 0.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.5 GO:0042287 MHC protein binding(GO:0042287)
0.0 1.4 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.1 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.1 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.6 PID P73PATHWAY p73 transcription factor network
0.0 0.5 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.6 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT