Project

PRJNA195909:zebrafish embryo and larva development

Navigation
Downloads

Results for hoxa1a+hoxb1b-1+hoxc1a

Z-value: 1.47

Motif logo

logo of

Transcription factors associated with hoxa1a+hoxb1b-1+hoxc1a

Gene Symbol Gene ID Gene Info
hoxb1b-1
ENSDARG00000054033 homeobox B1b
hoxc1a
ENSDARG00000070337 homeobox C1a
hoxa1a
ENSDARG00000104307 homeobox A1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc1adr11_v1_chr23_+_36178104_361781040.891.2e-03Click!
hoxa1adr11_v1_chr19_+_19786117_197862130.882.0e-03Click!
hoxb1bdr11_v1_chr12_+_27141140_271411400.752.0e-02Click!

Activity profile of hoxa1a+hoxb1b-1+hoxc1a motif

Sorted Z-values of hoxa1a+hoxb1b-1+hoxc1a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_1383914 4.88 ENSDART00000185089
cers2b
ceramide synthase 2b
chr3_-_55147731 4.66 ENSDART00000155871
ENSDART00000109016
ENSDART00000122904
hbae3
hemoglobin alpha embryonic-3
chr12_-_25916530 4.31 ENSDART00000186386
sncgb
synuclein, gamma b (breast cancer-specific protein 1)
chr7_+_29952719 3.28 ENSDART00000173737
tpma
alpha-tropomyosin
chr25_+_20215964 2.77 ENSDART00000139235
tnnt2d
troponin T2d, cardiac
chr6_+_29791164 2.67 ENSDART00000017424
ptmaa
prothymosin, alpha a
chr21_-_26495700 2.60 ENSDART00000109379
cd248b
CD248 molecule, endosialin b
chr20_-_32446406 2.52 ENSDART00000026635
nr2e1
nuclear receptor subfamily 2, group E, member 1
chr19_-_45985989 2.49 ENSDART00000165897
si:ch211-153f2.3
si:ch211-153f2.3
chr25_+_20216159 2.43 ENSDART00000048642
tnnt2d
troponin T2d, cardiac
chr13_-_39160018 2.39 ENSDART00000168795
col9a1b
collagen, type IX, alpha 1b
chr19_-_2231146 2.29 ENSDART00000181909
ENSDART00000043595
twist1a
twist family bHLH transcription factor 1a
chr18_-_23874929 2.09 ENSDART00000134910
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr17_+_40684 2.03 ENSDART00000164231
CABZ01111555.1

chr8_-_40464935 2.01 ENSDART00000040013
myl7
myosin, light chain 7, regulatory
chr18_-_23875370 1.89 ENSDART00000130163
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr20_-_9462433 1.88 ENSDART00000152674
ENSDART00000040557
zgc:101840
zgc:101840
chr18_+_24919614 1.74 ENSDART00000008638
rgma
repulsive guidance molecule family member a
chr22_-_34937455 1.66 ENSDART00000169217
ENSDART00000188330
ENSDART00000165142
slit1b
slit homolog 1b (Drosophila)
chr4_+_4816695 1.63 ENSDART00000136962
slc13a4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr22_-_600016 1.56 ENSDART00000086434
tmcc2
transmembrane and coiled-coil domain family 2
chr11_-_1131569 1.50 ENSDART00000173228
slc6a11b
solute carrier family 6 (neurotransmitter transporter), member 11b
chr18_-_23875219 1.43 ENSDART00000059976
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr5_-_66028714 1.42 ENSDART00000022625
ENSDART00000164228
nrarpb
NOTCH regulated ankyrin repeat protein b
chr16_-_31188715 1.41 ENSDART00000058829
scrt1b
scratch family zinc finger 1b
chr19_+_42219165 1.41 ENSDART00000163192
CU896644.1

chr23_-_12015139 1.37 ENSDART00000110627
ENSDART00000193988
ENSDART00000184528
si:dkey-178k16.1
si:dkey-178k16.1
chr22_-_15602593 1.36 ENSDART00000036075
tpm4a
tropomyosin 4a
chr3_+_23752150 1.36 ENSDART00000146636
hoxb2a
homeobox B2a
chr14_+_34547554 1.30 ENSDART00000074819
gabrp
gamma-aminobutyric acid (GABA) A receptor, pi
chr13_+_35745572 1.29 ENSDART00000159690
gpr75
G protein-coupled receptor 75
chr11_-_1509773 1.27 ENSDART00000050762
phactr3b
phosphatase and actin regulator 3b
chr20_-_35841570 1.26 ENSDART00000037855
tnfrsf21
tumor necrosis factor receptor superfamily, member 21
chr23_-_11870962 1.23 ENSDART00000143481
si:dkey-178k16.1
si:dkey-178k16.1
chr21_-_43079161 1.23 ENSDART00000144151
jakmip2
janus kinase and microtubule interacting protein 2
chr22_-_15602760 1.21 ENSDART00000009054
tpm4a
tropomyosin 4a
chr10_-_22127942 1.20 ENSDART00000133374
ponzr2
plac8 onzin related protein 2
chr13_-_43149063 1.19 ENSDART00000099601
vsir
V-set immunoregulatory receptor
chr20_-_29483514 1.19 ENSDART00000062370
actc1a
actin, alpha, cardiac muscle 1a
chr16_+_46111849 1.17 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr9_+_34425736 1.16 ENSDART00000135147
si:ch211-218d20.15
si:ch211-218d20.15
chr25_+_7461624 1.14 ENSDART00000170569
syt12
synaptotagmin XII
chr5_-_55600689 1.13 ENSDART00000013229
gnaq
guanine nucleotide binding protein (G protein), q polypeptide
chr6_+_52064304 1.10 ENSDART00000153468
abraa
actin binding Rho activating protein a
chr23_-_12014931 1.07 ENSDART00000134652
si:dkey-178k16.1
si:dkey-178k16.1
chr9_-_23217196 1.06 ENSDART00000083567
kif5c
kinesin family member 5C
chr21_-_31290582 1.05 ENSDART00000065362
ca4c
carbonic anhydrase IV c
chr14_-_7888748 1.05 ENSDART00000166293
ppp3cb
protein phosphatase 3, catalytic subunit, beta isozyme
chr14_+_24215046 1.03 ENSDART00000079215
stc2a
stanniocalcin 2a
chr19_-_47555956 1.01 ENSDART00000114549
actc1a
actin, alpha, cardiac muscle 1a
chr18_+_24922125 1.01 ENSDART00000180385
rgma
repulsive guidance molecule family member a
chr11_-_11471857 1.00 ENSDART00000030103
krt94
keratin 94
chr23_+_36178104 1.00 ENSDART00000103131
hoxc1a
homeobox C1a
chr18_-_42785469 1.00 ENSDART00000024768
ttc36
tetratricopeptide repeat domain 36
chr16_-_13730152 0.98 ENSDART00000138772
ttyh1
tweety family member 1
chr20_+_26349002 0.98 ENSDART00000152842
syne1a
spectrin repeat containing, nuclear envelope 1a
chr3_+_23768898 0.96 ENSDART00000110682
hoxb1a
homeobox B1a
chr24_+_119680 0.96 ENSDART00000061973
tgfbr1b
transforming growth factor, beta receptor 1 b
chr4_+_25706037 0.89 ENSDART00000141133
lamb1b
laminin, beta 1b
chr20_+_27691307 0.87 ENSDART00000153299
si:dkey-1h6.8
si:dkey-1h6.8
chr14_+_2478994 0.84 ENSDART00000170538
CU929317.1

chr4_+_11384891 0.84 ENSDART00000092381
ENSDART00000186577
ENSDART00000191054
ENSDART00000191584
pcloa
piccolo presynaptic cytomatrix protein a
chr11_-_21528056 0.84 ENSDART00000181626
srgap2
SLIT-ROBO Rho GTPase activating protein 2
chr20_-_47550577 0.80 ENSDART00000187361
CABZ01053323.1

chr8_-_10932206 0.80 ENSDART00000124313
nr1h5
nuclear receptor subfamily 1, group H, member 5
chr12_+_25945560 0.78 ENSDART00000109799
mmrn2b
multimerin 2b
chr6_-_13401133 0.77 ENSDART00000151206
fmnl2b
formin-like 2b
chr8_-_7440364 0.76 ENSDART00000180659
hdac6
histone deacetylase 6
chr10_+_439692 0.76 ENSDART00000147740
zdhhc8a
zinc finger, DHHC-type containing 8a
chr4_+_21129752 0.76 ENSDART00000169764
syt1a
synaptotagmin Ia
chr20_-_25369767 0.73 ENSDART00000180278
itsn2a
intersectin 2a
chr13_-_32577386 0.72 ENSDART00000016535
kcns3a
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3a
chr25_-_24074500 0.71 ENSDART00000040410
th
tyrosine hydroxylase
chr2_-_31754292 0.71 ENSDART00000192498
ralyl
RALY RNA binding protein like
chr7_+_25036188 0.70 ENSDART00000163957
ENSDART00000169749
sb:cb1058
sb:cb1058
chr3_+_15805917 0.70 ENSDART00000055834
phospho1
phosphatase, orphan 1
chr6_+_23752593 0.69 ENSDART00000164366
zgc:158654
zgc:158654
chr5_-_52921532 0.66 ENSDART00000160566
CU695117.1

chr9_+_11202552 0.66 ENSDART00000151931
asic4a
acid-sensing (proton-gated) ion channel family member 4a
chr17_+_51764310 0.63 ENSDART00000157171
si:ch211-168d23.3
si:ch211-168d23.3
chr8_+_18830759 0.62 ENSDART00000089079
mpnd
MPN domain containing
chr2_-_45630823 0.61 ENSDART00000183553
CR450720.1

chr15_+_59417 0.60 ENSDART00000187260
AXL
AXL receptor tyrosine kinase
chr5_-_22544151 0.60 ENSDART00000006474
glra4b
glycine receptor, alpha 4b
chr7_+_30371893 0.60 ENSDART00000075513
aqp9b
aquaporin 9b
chr10_-_31175744 0.60 ENSDART00000191728
pknox2
pbx/knotted 1 homeobox 2
chr6_-_29105727 0.59 ENSDART00000184355
fam69ab
family with sequence similarity 69, member Ab
chr17_+_22956427 0.57 ENSDART00000155145
ltbp1
latent transforming growth factor beta binding protein 1
chr24_+_34113424 0.56 ENSDART00000105572
gbx1
gastrulation brain homeobox 1
chr3_-_49925313 0.54 ENSDART00000164361
gcgra
glucagon receptor a
chr16_+_46401576 0.54 ENSDART00000130264
rpz
rapunzel
chr4_-_16641742 0.54 ENSDART00000180605
sinhcaf
SIN3-HDAC complex associated factor
chr9_-_51370293 0.54 ENSDART00000084806
slc4a10b
solute carrier family 4, sodium bicarbonate transporter, member 10b
chr10_-_27741793 0.53 ENSDART00000129369
ENSDART00000192440
ENSDART00000189808
ENSDART00000138149
auts2a
si:dkey-33o22.1
autism susceptibility candidate 2a
si:dkey-33o22.1
chr25_-_36827491 0.53 ENSDART00000170941
CU929365.1

chr21_+_43561650 0.52 ENSDART00000085071
gpr185a
G protein-coupled receptor 185 a
chr7_-_72067475 0.49 ENSDART00000017763
LO018380.1

chr16_+_14707960 0.48 ENSDART00000137912
col14a1a
collagen, type XIV, alpha 1a
chr4_-_14926637 0.47 ENSDART00000110199
prdm4
PR domain containing 4
chr14_+_19258702 0.46 ENSDART00000187087
ENSDART00000005738
slitrk2
SLIT and NTRK-like family, member 2
chr8_+_6410933 0.46 ENSDART00000168789
lrrtm4l2
leucine rich repeat transmembrane neuronal 4 like 2
chr7_+_16835218 0.45 ENSDART00000173580
nav2a
neuron navigator 2a
chr15_+_15456536 0.44 ENSDART00000109004
ENSDART00000156835
zgc:174895
zgc:174895
chr25_-_29987839 0.44 ENSDART00000154088
fam19a5b
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5b
chr22_+_635813 0.43 ENSDART00000179067
CU856139.1

chr17_-_6202816 0.41 ENSDART00000151908
ptk2ba
protein tyrosine kinase 2 beta, a
chr11_-_11458208 0.41 ENSDART00000005485
krt93
keratin 93
chr13_-_41908583 0.41 ENSDART00000136515
ipmka
inositol polyphosphate multikinase a
chr5_-_52277643 0.40 ENSDART00000010757
rgmb
repulsive guidance molecule family member b
chr12_+_39685485 0.36 ENSDART00000163403
LO017650.1

chr17_-_45009782 0.36 ENSDART00000123971
fam161b
family with sequence similarity 161, member B
chr4_-_13626831 0.35 ENSDART00000173077
si:dkeyp-81f3.4
si:dkeyp-81f3.4
chr1_+_10221568 0.35 ENSDART00000152424
npy2rl
neuropeptide Y receptor Y2, like
chr6_-_55585423 0.32 ENSDART00000157129
slc12a5a
solute carrier family 12 (potassium/chloride transporter), member 5a
chr22_+_3232925 0.31 ENSDART00000166754
CU929402.1

chr13_-_51065048 0.31 ENSDART00000168085
CABZ01078663.1

chr6_-_16561536 0.30 ENSDART00000167295
unc80
unc-80 homolog (C. elegans)
chr18_-_48755037 0.29 ENSDART00000109673
tirap
toll-interleukin 1 receptor (TIR) domain containing adaptor protein
chr23_+_21067684 0.29 ENSDART00000132066
kcnab2b
potassium voltage-gated channel, shaker-related subfamily, beta member 2 b
chr24_+_34806822 0.29 ENSDART00000148407
ENSDART00000188328
mchr2
melanin-concentrating hormone receptor 2
chr17_+_8183393 0.29 ENSDART00000155957
tulp4b
tubby like protein 4b
chr17_+_20607487 0.28 ENSDART00000154123
si:ch73-288o11.5
si:ch73-288o11.5
chr9_-_48296469 0.28 ENSDART00000058255
bbs5
Bardet-Biedl syndrome 5
chr15_+_15456910 0.27 ENSDART00000155708
zgc:174895
zgc:174895
chr13_-_2189761 0.26 ENSDART00000166255
mlip
muscular LMNA-interacting protein
chr1_-_47431453 0.26 ENSDART00000101104
gja5b
gap junction protein, alpha 5b
chr17_-_26604946 0.26 ENSDART00000087062
fam149b1
family with sequence similarity 149, member B1
chr10_-_26766780 0.26 ENSDART00000146666
mcf2b
MCF.2 cell line derived transforming sequence b
chr4_-_14926106 0.25 ENSDART00000147629
prdm4
PR domain containing 4
chr18_+_41542542 0.23 ENSDART00000087445
tsen34
TSEN34 tRNA splicing endonuclease subunit
chr7_+_31074636 0.23 ENSDART00000173805
tjp1a
tight junction protein 1a
chr3_-_214709 0.23 ENSDART00000098311
CABZ01079818.1

chr17_-_20394566 0.22 ENSDART00000154667
sorcs3b
sortilin related VPS10 domain containing receptor 3b
chr13_-_28272299 0.21 ENSDART00000006393
tlx1
T cell leukemia homeobox 1
chr1_+_20069535 0.20 ENSDART00000088653
prss12
protease, serine, 12 (neurotrypsin, motopsin)
chr17_-_19626357 0.19 ENSDART00000011432
reep3a
receptor accessory protein 3a
chr16_-_17300030 0.18 ENSDART00000149267
kel
Kell blood group, metallo-endopeptidase
chr8_-_44015210 0.17 ENSDART00000186879
ENSDART00000188965
ENSDART00000001313
ENSDART00000188902
ENSDART00000185935
ENSDART00000147869
rimbp2
rimbp2
RIMS binding protein 2
RIMS binding protein 2
chr15_-_27972474 0.16 ENSDART00000162753
CR391930.1

chr16_+_25196572 0.16 ENSDART00000141956
tyrobp
TYRO protein tyrosine kinase binding protein
chr2_-_16217344 0.15 ENSDART00000152031
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr7_+_21787507 0.14 ENSDART00000100936
tmem88b
transmembrane protein 88 b
chr2_+_6303639 0.13 ENSDART00000132859
otol1a
otolin 1a
chr23_-_333457 0.13 ENSDART00000114486
uhrf1bp1
UHRF1 binding protein 1
chr4_-_71983381 0.13 ENSDART00000169130
ftr64
finTRIM family, member 64
chr18_-_16392448 0.13 ENSDART00000180253
mgat4c
mgat4 family, member C
chr17_+_45009868 0.12 ENSDART00000085009
coq6
coenzyme Q6 monooxygenase
chr11_+_33628104 0.11 ENSDART00000165318
thsd7bb
thrombospondin, type I, domain containing 7Bb
chr9_+_22351443 0.10 ENSDART00000080054
crygs3
crystallin, gamma S3
chr13_+_37273010 0.10 ENSDART00000144387
gphb5
glycoprotein hormone beta 5
chr25_+_12849609 0.10 ENSDART00000168144
ccl33.2
chemokine (C-C motif) ligand 33, duplicate 2
chr3_+_46628885 0.10 ENSDART00000006602
pde4a
phosphodiesterase 4A, cAMP-specific
chr17_-_26604549 0.09 ENSDART00000174773
fam149b1
family with sequence similarity 149, member B1
chr22_+_38778649 0.09 ENSDART00000075873
alpi.2
alkaline phosphatase, intestinal, tandem duplicate 2
chr8_-_52745141 0.09 ENSDART00000168359
ENSDART00000168252
fgf17
fibroblast growth factor 17
chr20_-_28842524 0.09 ENSDART00000046035
ENSDART00000139843
ENSDART00000129858
ENSDART00000137425
ENSDART00000135720
max
myc associated factor X
chr16_-_20932896 0.09 ENSDART00000180646
tax1bp1b
Tax1 (human T-cell leukemia virus type I) binding protein 1b
chr5_+_61976511 0.07 ENSDART00000050885
ehd2a
EH-domain containing 2a
chr7_-_7810348 0.07 ENSDART00000171984
cxcl19
chemokine (C-X-C motif) ligand 19
chr5_+_61301525 0.06 ENSDART00000128773
doc2b
double C2-like domains, beta
chr24_+_26039464 0.06 ENSDART00000131017
tnk2a
tyrosine kinase, non-receptor, 2a
chr4_+_74226447 0.06 ENSDART00000174336
ENSDART00000191455
ENSDART00000180062
ptprr
protein tyrosine phosphatase, receptor type, r
chr7_-_18617187 0.05 ENSDART00000172419
si:ch211-119e14.1
si:ch211-119e14.1
chr22_+_38778854 0.04 ENSDART00000182926
ENSDART00000125466
alpi.2
alkaline phosphatase, intestinal, tandem duplicate 2
chr8_-_39739056 0.02 ENSDART00000147992
si:ch211-170d8.5
si:ch211-170d8.5
chr16_-_16761164 0.02 ENSDART00000135872
si:dkey-27n14.1
si:dkey-27n14.1
chr12_-_36268723 0.02 ENSDART00000113740
kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr17_-_49481672 0.01 ENSDART00000166394
fcf1
FCF1 rRNA-processing protein
chr2_+_22765492 0.00 ENSDART00000133222
espnlb
espin like b

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa1a+hoxb1b-1+hoxc1a

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.4 GO:0060843 lymphatic endothelial cell fate commitment(GO:0060838) venous endothelial cell differentiation(GO:0060843) venous endothelial cell fate commitment(GO:0060845)
0.5 2.7 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.4 1.3 GO:0031642 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.4 2.2 GO:0003272 endocardial cushion formation(GO:0003272)
0.3 2.0 GO:0055014 ventricular cardiac myofibril assembly(GO:0055005) atrial cardiac muscle cell development(GO:0055014)
0.3 1.0 GO:0021570 rhombomere 4 development(GO:0021570) rhombomere 4 morphogenesis(GO:0021661)
0.2 0.7 GO:0042416 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.2 4.7 GO:0015671 oxygen transport(GO:0015671)
0.2 4.3 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.2 0.8 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.2 1.1 GO:0098971 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 1.4 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 2.6 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 5.2 GO:0006937 regulation of muscle contraction(GO:0006937)
0.1 0.6 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.1 0.8 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.8 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 1.2 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 4.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 1.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.3 GO:0072003 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.1 0.1 GO:0045299 otolith mineralization(GO:0045299)
0.1 2.3 GO:0060037 pharyngeal system development(GO:0060037)
0.1 3.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 0.2 GO:0071635 negative regulation of B cell proliferation(GO:0030889) regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) negative regulation of B cell activation(GO:0050869) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635)
0.0 1.4 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.3 GO:0051969 regulation of transmission of nerve impulse(GO:0051969)
0.0 1.7 GO:0021602 cranial nerve morphogenesis(GO:0021602)
0.0 1.1 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 0.6 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 1.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.4 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.1 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 3.2 GO:0061515 myeloid cell development(GO:0061515)
0.0 1.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.5 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.5 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.1 GO:0001508 action potential(GO:0001508)
0.0 0.2 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.4 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.3 GO:0097324 adult behavior(GO:0030534) melanocyte migration(GO:0097324)
0.0 1.1 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 1.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.6 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 0.1 GO:0042664 negative regulation of endodermal cell fate specification(GO:0042664)
0.0 0.5 GO:0010675 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.0 1.0 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.5 GO:0006821 chloride transport(GO:0006821)
0.0 0.5 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 3.1 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.8 GO:0060216 definitive hemopoiesis(GO:0060216)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 1.0 GO:0005955 calcineurin complex(GO:0005955)
0.2 0.8 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 1.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 2.2 GO:0005869 dynactin complex(GO:0005869)
0.1 3.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 5.2 GO:0005861 troponin complex(GO:0005861)
0.1 4.5 GO:0043679 axon terminus(GO:0043679)
0.1 0.8 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 1.0 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 5.8 GO:0005884 actin filament(GO:0005884)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.9 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.3 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.8 GO:0045335 dendritic spine head(GO:0044327) phagocytic vesicle(GO:0045335)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 2.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.7 GO:0043204 perikaryon(GO:0043204)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 1.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 2.6 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:1903136 cuprous ion binding(GO:1903136)
0.9 2.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.7 5.4 GO:0001972 retinoic acid binding(GO:0001972)
0.5 5.2 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.4 4.7 GO:0031720 haptoglobin binding(GO:0031720)
0.4 2.7 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.3 4.9 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 0.7 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 0.7 GO:0003999 adenine phosphoribosyltransferase activity(GO:0003999)
0.2 0.8 GO:0042903 tubulin deacetylase activity(GO:0042903) acetylspermidine deacetylase activity(GO:0047611)
0.2 1.0 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 3.2 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.6 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.1 1.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.4 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 1.5 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 1.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.5 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.1 1.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.7 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.3 GO:0005521 lamin binding(GO:0005521)
0.1 0.6 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.3 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.8 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 1.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.8 GO:0031267 small GTPase binding(GO:0031267)
0.0 1.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.6 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.7 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 2.9 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 2.9 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.4 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.2 5.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.1 PID BMP PATHWAY BMP receptor signaling
0.1 1.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 3.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 5.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 2.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 0.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.3 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1