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PRJNA195909:zebrafish embryo and larva development

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Results for hoxa2b

Z-value: 0.61

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Transcription factors associated with hoxa2b

Gene Symbol Gene ID Gene Info
hoxa2b
ENSDARG00000023031 homeobox A2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxa2bdr11_v1_chr16_+_20926673_209266730.442.4e-01Click!

Activity profile of hoxa2b motif

Sorted Z-values of hoxa2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr24_+_38301080 1.87 ENSDART00000105672
mybpc2b
myosin binding protein C, fast type b
chr9_-_22135420 0.70 ENSDART00000184959
crygm2d8
crystallin, gamma M2d8
chr9_-_45601103 0.63 ENSDART00000180465
agr1
anterior gradient 1
chr25_+_20215964 0.62 ENSDART00000139235
tnnt2d
troponin T2d, cardiac
chr9_-_22099536 0.62 ENSDART00000101923
CR391987.1

chr25_+_20216159 0.56 ENSDART00000048642
tnnt2d
troponin T2d, cardiac
chr7_+_29952719 0.53 ENSDART00000173737
tpma
alpha-tropomyosin
chr12_-_11457625 0.52 ENSDART00000012318
htra1b
HtrA serine peptidase 1b
chr3_-_32818607 0.52 ENSDART00000075465
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr7_-_8374950 0.52 ENSDART00000057101
aep1
aerolysin-like protein
chr9_-_22232902 0.50 ENSDART00000101845
crygm2d5
crystallin, gamma M2d5
chr9_-_22135576 0.49 ENSDART00000101902
crygm2d8
crystallin, gamma M2d8
chr14_-_36378494 0.42 ENSDART00000058503
gpm6aa
glycoprotein M6Aa
chr23_+_5490854 0.39 ENSDART00000175403
tulp1a
tubby like protein 1a
chr1_+_17676745 0.38 ENSDART00000030665
slc25a4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr7_-_8417315 0.38 ENSDART00000173046
jac1
jacalin 1
chr9_-_44295071 0.37 ENSDART00000011837
neurod1
neuronal differentiation 1
chr9_-_22310919 0.36 ENSDART00000108719
crygm2d10
crystallin, gamma M2d10
chr5_+_37837245 0.36 ENSDART00000171617
epd
ependymin
chr12_-_25916530 0.35 ENSDART00000186386
sncgb
synuclein, gamma b (breast cancer-specific protein 1)
chr2_-_722156 0.34 ENSDART00000045770
ENSDART00000169498
foxq1a
forkhead box Q1a
chr4_+_12931763 0.33 ENSDART00000016382
wif1
wnt inhibitory factor 1
chr4_-_16333944 0.33 ENSDART00000079523
epyc
epiphycan
chr23_-_18609475 0.32 ENSDART00000104524
zgc:158296
zgc:158296
chr19_+_1835940 0.32 ENSDART00000167372
ptk2aa
protein tyrosine kinase 2aa
chr14_+_25465346 0.31 ENSDART00000173436
si:dkey-280e21.3
si:dkey-280e21.3
chr22_-_600016 0.31 ENSDART00000086434
tmcc2
transmembrane and coiled-coil domain family 2
chr4_+_21129752 0.31 ENSDART00000169764
syt1a
synaptotagmin Ia
chr2_+_47623202 0.30 ENSDART00000154465
si:ch211-165b10.3
si:ch211-165b10.3
chr1_+_16144615 0.30 ENSDART00000054707
tusc3
tumor suppressor candidate 3
chr7_-_24472991 0.30 ENSDART00000121684
nat8l
N-acetyltransferase 8-like
chr5_+_32221755 0.30 ENSDART00000125917
myhc4
myosin heavy chain 4
chr13_+_1726953 0.29 ENSDART00000103004
zmp:0000000760
zmp:0000000760
chr5_+_36932718 0.29 ENSDART00000037879
crx
cone-rod homeobox
chr12_-_26406323 0.29 ENSDART00000131896
myoz1b
myozenin 1b
chr25_+_19105804 0.28 ENSDART00000104414
rlbp1b
retinaldehyde binding protein 1b
chr2_-_2020044 0.27 ENSDART00000024135
tubb2
tubulin, beta 2A class IIa
chr3_+_23752150 0.27 ENSDART00000146636
hoxb2a
homeobox B2a
chr21_-_43079161 0.27 ENSDART00000144151
jakmip2
janus kinase and microtubule interacting protein 2
chr16_+_20904754 0.27 ENSDART00000006043
hoxa11b
homeobox A11b
chr16_+_12022543 0.27 ENSDART00000012673
gnb3a
guanine nucleotide binding protein (G protein), beta polypeptide 3a
chr16_-_45058919 0.27 ENSDART00000177134
gapdhs
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr13_+_23282549 0.27 ENSDART00000101134
khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr10_-_39011514 0.27 ENSDART00000075123
pcp4a
Purkinje cell protein 4a
chr23_-_11870962 0.26 ENSDART00000143481
si:dkey-178k16.1
si:dkey-178k16.1
chr12_+_48241841 0.26 ENSDART00000168616
ppa1a
pyrophosphatase (inorganic) 1a
chr16_-_45225520 0.26 ENSDART00000158855
fxyd1
FXYD domain containing ion transport regulator 1 (phospholemman)
chr11_-_22605981 0.26 ENSDART00000186923
myog
myogenin
chr1_-_46981134 0.26 ENSDART00000130607
pknox1.2
pbx/knotted 1 homeobox 1.2
chr6_+_29791164 0.26 ENSDART00000017424
ptmaa
prothymosin, alpha a
chr8_-_16697912 0.25 ENSDART00000076542
rpe65b
retinal pigment epithelium-specific protein 65b
chr18_+_13792490 0.25 ENSDART00000136754
cdh13
cadherin 13, H-cadherin (heart)
chr25_-_13363286 0.25 ENSDART00000163735
ENSDART00000169119
ndrg4
NDRG family member 4
chr1_-_26294995 0.24 ENSDART00000168594
cxxc4
CXXC finger 4
chr12_+_39685485 0.24 ENSDART00000163403
LO017650.1

chr2_+_27010439 0.24 ENSDART00000030547
cdh7a
cadherin 7a
chr4_+_76575585 0.24 ENSDART00000131588
ms4a17a.11
membrane-spanning 4-domains, subfamily A, member 17A.11
chr8_+_22931427 0.24 ENSDART00000063096
sypa
synaptophysin a
chr5_-_20194876 0.24 ENSDART00000122587
dao.1
D-amino-acid oxidase, tandem duplicate 1
chr24_-_6897884 0.24 ENSDART00000080766
dpp6a
dipeptidyl-peptidase 6a
chr1_-_59252973 0.24 ENSDART00000167061
si:ch1073-286c18.5
si:ch1073-286c18.5
chr22_+_12770877 0.24 ENSDART00000044683
ftcd
formimidoyltransferase cyclodeaminase
chr6_+_15268685 0.23 ENSDART00000128090
ENSDART00000154417
ecrg4b
esophageal cancer related gene 4b
chr23_+_4689626 0.23 ENSDART00000131532
gp9
glycoprotein IX (platelet)
chr10_+_20128267 0.23 ENSDART00000064615
dmtn
dematin actin binding protein
chr7_+_26629084 0.23 ENSDART00000101044
ENSDART00000173765
hsbp1a
heat shock factor binding protein 1a
chr10_-_20453995 0.23 ENSDART00000168541
ENSDART00000164072
si:ch211-113d22.2
si:ch211-113d22.2
chr14_+_34486629 0.23 ENSDART00000131861
tmsb2
thymosin beta 2
chr10_-_20445549 0.22 ENSDART00000064613
loxl2a
lysyl oxidase-like 2a
chr4_+_17279966 0.22 ENSDART00000067005
ENSDART00000137487
bcat1
branched chain amino-acid transaminase 1, cytosolic
chr21_+_6751405 0.22 ENSDART00000037265
ENSDART00000146371
olfm1b
olfactomedin 1b
chr3_+_40809011 0.22 ENSDART00000033713
arpc1b
actin related protein 2/3 complex, subunit 1B
chr20_-_8443425 0.22 ENSDART00000083908
dab1a
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr18_-_12052132 0.22 ENSDART00000074361
zgc:110789
zgc:110789
chr1_+_46194333 0.22 ENSDART00000010894
sox1b
SRY (sex determining region Y)-box 1b
chr2_-_31634978 0.21 ENSDART00000135668
si:ch211-106h4.9
si:ch211-106h4.9
chr7_-_13882988 0.21 ENSDART00000169828
rlbp1a
retinaldehyde binding protein 1a
chr20_+_23238833 0.21 ENSDART00000074167
ociad2
OCIA domain containing 2
chr15_+_32268790 0.21 ENSDART00000154457
fhdc4
FH2 domain containing 4
chr14_-_52542928 0.21 ENSDART00000075749
ppp2r2ba
protein phosphatase 2, regulatory subunit B, beta a
chr14_+_13454840 0.20 ENSDART00000161854
pls3
plastin 3 (T isoform)
chr12_-_4346085 0.20 ENSDART00000112433
ca15c
carbonic anhydrase XV c
chr23_+_10146542 0.20 ENSDART00000048073
zgc:171775
zgc:171775
chr20_-_9462433 0.20 ENSDART00000152674
ENSDART00000040557
zgc:101840
zgc:101840
chr21_-_28920245 0.20 ENSDART00000132884
cxxc5a
CXXC finger protein 5a
chr11_-_7320211 0.20 ENSDART00000091664
apc2
adenomatosis polyposis coli 2
chr16_+_10776688 0.20 ENSDART00000161969
ENSDART00000172657
atp1a3b
ATPase Na+/K+ transporting subunit alpha 3b
chr10_+_439692 0.19 ENSDART00000147740
zdhhc8a
zinc finger, DHHC-type containing 8a
chr1_-_10071422 0.19 ENSDART00000135522
ENSDART00000033118
fga
fibrinogen alpha chain
chr13_+_29770837 0.19 ENSDART00000076998
pax2a
paired box 2a
chr7_+_46252993 0.19 ENSDART00000167149
znf536
zinc finger protein 536
chr24_+_119680 0.19 ENSDART00000061973
tgfbr1b
transforming growth factor, beta receptor 1 b
chr17_-_20897250 0.19 ENSDART00000088106
ank3b
ankyrin 3b
chr18_-_42785469 0.19 ENSDART00000024768
ttc36
tetratricopeptide repeat domain 36
chr24_-_26310854 0.19 ENSDART00000080113
apodb
apolipoprotein Db
chr10_-_26744131 0.19 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fgf13b
fibroblast growth factor 13b
chr21_-_44512893 0.19 ENSDART00000166853
zgc:136410
zgc:136410
chr13_+_9432501 0.19 ENSDART00000058064
zgc:123321
zgc:123321
chr25_-_31396479 0.18 ENSDART00000156828
prr33
proline rich 33
chr5_-_20195350 0.18 ENSDART00000139675
dao.1
D-amino-acid oxidase, tandem duplicate 1
chr11_+_26476153 0.18 ENSDART00000103507
unm_sa1614
un-named sa1614
chr9_+_48007081 0.18 ENSDART00000060593
ENSDART00000099835
zgc:92380
zgc:92380
chr1_+_52929185 0.18 ENSDART00000147683
inpp4b
inositol polyphosphate-4-phosphatase type II B
chr18_+_15706160 0.17 ENSDART00000131524
si:ch211-264e16.1
si:ch211-264e16.1
chr3_+_27027781 0.17 ENSDART00000065495
emp2
epithelial membrane protein 2
chr4_+_26496489 0.17 ENSDART00000160652
iqsec3a
IQ motif and Sec7 domain 3a
chr17_-_49800869 0.17 ENSDART00000156264
col12a1a
collagen, type XII, alpha 1a
chr13_+_22249636 0.17 ENSDART00000108472
ENSDART00000173123
synpo2la
synaptopodin 2-like a
chr9_+_22003942 0.17 ENSDART00000091013
si:dkey-57a22.15
si:dkey-57a22.15
chr1_+_16127825 0.17 ENSDART00000122503
tusc3
tumor suppressor candidate 3
chr8_+_28527776 0.17 ENSDART00000053782
scrt2
scratch family zinc finger 2
chr3_-_26109322 0.17 ENSDART00000113780
zgc:162612
zgc:162612
chr16_+_46111849 0.17 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr7_+_20503344 0.17 ENSDART00000157699
si:dkey-19b23.12
si:dkey-19b23.12
chr10_+_35417099 0.17 ENSDART00000063398
hhla2a.1
HERV-H LTR-associating 2a, tandem duplicate 1
chr4_-_5597802 0.17 ENSDART00000136229
vegfab
vascular endothelial growth factor Ab
chr12_+_5189776 0.17 ENSDART00000081298
lgi1b
leucine-rich, glioma inactivated 1b
chr13_-_5569562 0.16 ENSDART00000102576
meis1b
Meis homeobox 1 b
chr4_-_16412084 0.16 ENSDART00000188460
dcn
decorin
chr7_+_35229645 0.16 ENSDART00000144327
tppp3
tubulin polymerization-promoting protein family member 3
chr24_-_6898302 0.16 ENSDART00000158646
dpp6a
dipeptidyl-peptidase 6a
chr19_-_48312109 0.16 ENSDART00000161103
si:ch73-359m17.9
si:ch73-359m17.9
chr1_-_51465730 0.16 ENSDART00000074284
spred2a
sprouty-related, EVH1 domain containing 2a
chr18_-_46010 0.16 ENSDART00000052641
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr20_-_53992952 0.16 ENSDART00000170138
hsp90aa1.1
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1
chr11_-_21586157 0.16 ENSDART00000190095
srgap2
SLIT-ROBO Rho GTPase activating protein 2
chr22_+_34701848 0.16 ENSDART00000082066
atpv0e2
ATPase H+ transporting V0 subunit e2
chr20_-_35841570 0.16 ENSDART00000037855
tnfrsf21
tumor necrosis factor receptor superfamily, member 21
chr15_-_26552652 0.16 ENSDART00000152336
serpinf2b
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr13_-_31435137 0.15 ENSDART00000057441
rtn1a
reticulon 1a
chr10_+_21511495 0.15 ENSDART00000178395
BX957322.3

chr15_+_45640906 0.15 ENSDART00000149361
ENSDART00000149079
sagb
S-antigen; retina and pineal gland (arrestin) b
chr10_+_34377697 0.15 ENSDART00000189441
stard13a
StAR-related lipid transfer (START) domain containing 13a
chr25_+_15354095 0.15 ENSDART00000090397
kiaa1549la
KIAA1549-like a
chr19_-_42607451 0.15 ENSDART00000004392
fkbp9
FK506 binding protein 9
chr8_-_54223316 0.15 ENSDART00000018054
trh
thyrotropin-releasing hormone
chr16_-_54942532 0.15 ENSDART00000078887
ENSDART00000101402
tmem222a
transmembrane protein 222a
chr23_+_36095260 0.15 ENSDART00000127384
hoxc9a
homeobox C9a
chr9_+_17438765 0.15 ENSDART00000138953
rgcc
regulator of cell cycle
chr21_-_27338639 0.15 ENSDART00000130632
hif1al2
hypoxia-inducible factor 1, alpha subunit, like 2
chr8_-_20380750 0.15 ENSDART00000113910
adamts10
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr18_-_8877077 0.15 ENSDART00000137266
si:dkey-95h12.2
si:dkey-95h12.2
chr24_+_13735616 0.15 ENSDART00000184267
msc
musculin (activated B-cell factor-1)
chr22_-_33679277 0.14 ENSDART00000169948
FO904977.1

chr25_-_18953322 0.14 ENSDART00000155927
si:ch211-68a17.7
si:ch211-68a17.7
chr25_+_21833287 0.14 ENSDART00000187606
ckmt1
creatine kinase, mitochondrial 1
chr3_+_33300522 0.14 ENSDART00000114023
hspb9
heat shock protein, alpha-crystallin-related, 9
chr13_-_1349922 0.14 ENSDART00000140970
si:ch73-52p7.1
si:ch73-52p7.1
chr23_-_19500559 0.14 ENSDART00000177414
ENSDART00000145898
asb14b
ankyrin repeat and SOCS box containing 14b
chr10_+_3875716 0.14 ENSDART00000189268
ENSDART00000180624
TTC28
tetratricopeptide repeat domain 28
chr11_-_1509773 0.14 ENSDART00000050762
phactr3b
phosphatase and actin regulator 3b
chr21_+_6961635 0.14 ENSDART00000137281
si:ch211-93g21.2
si:ch211-93g21.2
chr7_-_51321126 0.14 ENSDART00000067647
rasl11a
RAS-like, family 11, member A
chr1_-_25966068 0.14 ENSDART00000137869
ENSDART00000134192
synpo2b
synaptopodin 2b
chr3_+_23726148 0.14 ENSDART00000174580
hoxb3a
homeobox B3a
chr7_-_34475696 0.14 ENSDART00000058095
si:zfos-1897c11.1
si:zfos-1897c11.1
chr2_-_26001173 0.14 ENSDART00000010615
cldn11a
claudin 11a
chr5_+_36693859 0.14 ENSDART00000019259
dlb
deltaB
chr6_-_29105727 0.14 ENSDART00000184355
fam69ab
family with sequence similarity 69, member Ab
chr16_-_37964325 0.14 ENSDART00000148801
mrap2a
melanocortin 2 receptor accessory protein 2a
chr14_+_109016 0.14 ENSDART00000158405
gpc2
glypican 2
chr23_+_6795709 0.14 ENSDART00000149136
si:ch211-117c9.5
si:ch211-117c9.5
chr13_-_21688176 0.14 ENSDART00000063825
sprn
shadow of prion protein
chr4_-_2545310 0.14 ENSDART00000150619
ENSDART00000140760
e2f7
E2F transcription factor 7
chr11_+_25472758 0.14 ENSDART00000011178
opn1sw2
opsin 1 (cone pigments), short-wave-sensitive 2
chr16_-_31188715 0.14 ENSDART00000058829
scrt1b
scratch family zinc finger 1b
chr18_-_48745517 0.14 ENSDART00000097259
st3gal4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr16_-_54455573 0.14 ENSDART00000075275
pklr
pyruvate kinase L/R
chr4_-_25485404 0.13 ENSDART00000041402
pfkfb3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr12_-_28881638 0.13 ENSDART00000148459
ENSDART00000039667
ENSDART00000148668
ENSDART00000136593
ENSDART00000139923
ENSDART00000148912
cbx1b
chromobox homolog 1b (HP1 beta homolog Drosophila)
chr7_-_20453661 0.13 ENSDART00000174001
ntn5
netrin 5
chr10_+_7798087 0.13 ENSDART00000141824
sftpba
surfactant protein Ba
chr1_+_29281764 0.13 ENSDART00000112106
fam155a
family with sequence similarity 155, member A
chr13_-_32577386 0.13 ENSDART00000016535
kcns3a
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3a
chr20_+_19512727 0.13 ENSDART00000063696
atraid
all-trans retinoic acid-induced differentiation factor
chr18_+_30847237 0.13 ENSDART00000012374
foxf1
forkhead box F1
chr3_+_60721342 0.13 ENSDART00000157772
foxj1a
forkhead box J1a
chr23_+_2361184 0.13 ENSDART00000184469
CABZ01048666.1

chr23_-_20309505 0.13 ENSDART00000130856
lamb2l
laminin, beta 2-like
chr8_+_44420108 0.13 ENSDART00000075381
CU571323.1

chr8_-_42624454 0.13 ENSDART00000075550
kazald3
Kazal-type serine peptidase inhibitor domain 3
chr12_+_48634927 0.13 ENSDART00000168441
zgc:165653
zgc:165653
chr22_+_20208185 0.13 ENSDART00000142748
si:dkey-110c1.7
si:dkey-110c1.7
chr7_+_73593814 0.13 ENSDART00000110544
znf219
zinc finger protein 219
chr17_-_49978986 0.13 ENSDART00000154728
col12a1a
collagen, type XII, alpha 1a
chr6_-_16406210 0.13 ENSDART00000012023
faimb
Fas apoptotic inhibitory molecule b
chr11_+_36243774 0.13 ENSDART00000023323
zgc:172270
zgc:172270
chr21_-_40174647 0.13 ENSDART00000183738
ENSDART00000076840
ENSDART00000145109
slco2b1
solute carrier organic anion transporter family, member 2B1
chr10_+_17850934 0.13 ENSDART00000113666
ENSDART00000145936
phf24
PHD finger protein 24
chr10_-_4316015 0.13 ENSDART00000109916
ENSDART00000180867
grin3a
glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
chr20_+_7243879 0.13 ENSDART00000122298
bsnd
barttin CLCNK-type chloride channel accessory beta subunit
chr16_-_35952789 0.12 ENSDART00000180118
eva1ba
eva-1 homolog Ba (C. elegans)
chr17_-_10838434 0.12 ENSDART00000064597
lgals3b
lectin, galactoside binding soluble 3b
chr5_+_64842730 0.12 ENSDART00000144732
lrrc8ab
leucine rich repeat containing 8 VRAC subunit Ab
chr15_+_45643787 0.12 ENSDART00000055995
ENSDART00000157750
sagb
S-antigen; retina and pineal gland (arrestin) b
chr6_+_41186320 0.12 ENSDART00000025241
opn1mw2
opsin 1 (cone pigments), medium-wave-sensitive, 2
chr23_-_44226556 0.12 ENSDART00000149115
zgc:158659
zgc:158659
chr22_+_24715282 0.12 ENSDART00000088027
ENSDART00000189054
ENSDART00000140430
ssx2ipb
synovial sarcoma, X breakpoint 2 interacting protein b
chr24_-_23942722 0.12 ENSDART00000080810
arxa
aristaless related homeobox a
chr16_+_1254390 0.12 ENSDART00000092627
ADAMTSL4
ADAMTS like 4

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 GO:0051580 regulation of neurotransmitter uptake(GO:0051580)
0.1 0.4 GO:0006524 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.1 0.4 GO:0015867 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.1 0.2 GO:0043606 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.2 GO:0070314 G1 to G0 transition(GO:0070314)
0.1 0.3 GO:1901825 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.1 0.2 GO:0003071 renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071) regulation of glomerular filtration(GO:0003093)
0.1 0.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 0.2 GO:0009098 leucine biosynthetic process(GO:0009098)
0.1 0.3 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.2 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.1 0.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.2 GO:0031645 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692) negative regulation of anion transport(GO:1903792)
0.0 0.1 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.2 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.2 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.0 0.2 GO:0045429 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
0.0 0.4 GO:0044854 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0005985 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.0 0.0 GO:0071635 regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635)
0.0 0.1 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.2 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.2 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.1 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.1 GO:0070316 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.5 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0032877 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.0 0.2 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.1 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.2 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.1 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.1 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.3 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.0 0.2 GO:0021588 cerebellum formation(GO:0021588)
0.0 0.1 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0032965 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.0 0.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.2 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 0.3 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.3 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 1.2 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.0 0.6 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.4 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.0 0.2 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516)
0.0 0.1 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.1 GO:0070292 N-acylphosphatidylethanolamine metabolic process(GO:0070292)
0.0 0.1 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.0 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.0 0.1 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.0 0.0 GO:0051610 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
0.0 0.3 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.1 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 2.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.1 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.3 GO:0060034 notochord cell differentiation(GO:0060034)
0.0 0.1 GO:0006531 aspartate metabolic process(GO:0006531)
0.0 0.1 GO:0072673 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.0 0.1 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 0.3 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.1 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.0 0.2 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.2 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0 0.3 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.1 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.0 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
0.0 0.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.4 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.3 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.0 0.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.1 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.3 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.1 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 0.1 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.0 0.1 GO:1902042 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.3 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.1 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.1 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.2 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.1 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.0 GO:0015677 copper ion import(GO:0015677)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0001772 immunological synapse(GO:0001772)
0.0 1.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0034359 mature chylomicron(GO:0034359)
0.0 0.2 GO:0030428 cell septum(GO:0030428)
0.0 0.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.5 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.6 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.1 GO:0032433 filopodium tip(GO:0032433)
0.0 0.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.7 GO:0016342 catenin complex(GO:0016342)
0.0 0.5 GO:0043679 axon terminus(GO:0043679)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.3 GO:1903136 cuprous ion binding(GO:1903136)
0.1 1.2 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 0.4 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.1 0.4 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.1 0.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.3 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.3 GO:0050251 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.1 0.4 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.2 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.3 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.0 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0019809 spermidine binding(GO:0019809)
0.0 0.1 GO:0031782 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.3 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.0 2.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0004100 chitin synthase activity(GO:0004100)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.1 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.0 0.1 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.0 GO:0005335 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.0 0.1 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.0 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.0 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.0 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.0 0.0 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions