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PRJNA195909:zebrafish embryo and larva development

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Results for hoxa9a+hoxa9b

Z-value: 0.86

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Transcription factors associated with hoxa9a+hoxa9b

Gene Symbol Gene ID Gene Info
hoxa9b
ENSDARG00000056819 homeobox A9b
hoxa9a
ENSDARG00000105013 homeobox A9a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxa9bdr11_v1_chr16_+_20915319_209153190.353.6e-01Click!
hoxa9adr11_v1_chr19_+_19747430_197474300.235.5e-01Click!

Activity profile of hoxa9a+hoxa9b motif

Sorted Z-values of hoxa9a+hoxa9b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_47633438 1.38 ENSDART00000139096
si:ch211-251b21.1
si:ch211-251b21.1
chr9_-_22299412 1.05 ENSDART00000139101
crygm2d21
crystallin, gamma M2d21
chr5_-_32274383 0.89 ENSDART00000122889
myhz1.3
myosin, heavy polypeptide 1.3, skeletal muscle
chr3_+_32526263 0.81 ENSDART00000150897
si:ch73-367p23.2
si:ch73-367p23.2
chr11_-_6048490 0.77 ENSDART00000066164
plvapb
plasmalemma vesicle associated protein b
chr8_+_6954984 0.72 ENSDART00000145610
si:ch211-255g12.6
si:ch211-255g12.6
chr5_+_36932718 0.71 ENSDART00000037879
crx
cone-rod homeobox
chr2_+_2223837 0.71 ENSDART00000101038
ENSDART00000129354
tmie
transmembrane inner ear
chr5_+_32206378 0.66 ENSDART00000126873
ENSDART00000051361
myhz2
myosin, heavy polypeptide 2, fast muscle specific
chr7_-_8417315 0.62 ENSDART00000173046
jac1
jacalin 1
chr7_-_8374950 0.62 ENSDART00000057101
aep1
aerolysin-like protein
chr2_-_5728843 0.60 ENSDART00000014020
sst2
somatostatin 2
chr1_+_7546259 0.59 ENSDART00000015732
mylz3
myosin, light polypeptide 3, skeletal muscle
chr6_+_27151940 0.58 ENSDART00000088364
kif1aa
kinesin family member 1Aa
chr12_-_26406323 0.57 ENSDART00000131896
myoz1b
myozenin 1b
chr3_+_40809011 0.56 ENSDART00000033713
arpc1b
actin related protein 2/3 complex, subunit 1B
chr6_-_46875310 0.54 ENSDART00000154442
igfn1.3
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr7_+_39386982 0.53 ENSDART00000146702
tnni2b.2
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr15_+_32711172 0.50 ENSDART00000163936
ENSDART00000168135
postnb
periostin, osteoblast specific factor b
chr21_-_25685422 0.50 ENSDART00000182921
phkg1b
phosphorylase kinase, gamma 1b (muscle)
chr19_-_6385594 0.49 ENSDART00000104950
atp1a3a
ATPase Na+/K+ transporting subunit alpha 3a
chr3_+_33300522 0.47 ENSDART00000114023
hspb9
heat shock protein, alpha-crystallin-related, 9
chr22_-_11493236 0.45 ENSDART00000002691
tspan7b
tetraspanin 7b
chr11_-_11266882 0.44 ENSDART00000020256
lgsn
lengsin, lens protein with glutamine synthetase domain
chr15_+_33070939 0.44 ENSDART00000164928
mab21l1
mab-21-like 1
chr12_+_26467847 0.43 ENSDART00000022495
ndel1a
nudE neurodevelopment protein 1-like 1a
chr11_-_6188413 0.42 ENSDART00000109972
ccl44
chemokine (C-C motif) ligand 44
chr7_-_4036184 0.42 ENSDART00000019949
ndrg2
NDRG family member 2
chr2_-_48196092 0.41 ENSDART00000139944
snorc
secondary ossification center associated regulator of chondrocyte maturation
chr7_+_31879649 0.41 ENSDART00000099789
mybpc3
myosin binding protein C, cardiac
chr9_-_296169 0.40 ENSDART00000165228
kif5aa
kinesin family member 5A, a
chr7_+_48761875 0.40 ENSDART00000003690
acana
aggrecan a
chr12_+_16440708 0.39 ENSDART00000113810
ankrd1b
ankyrin repeat domain 1b (cardiac muscle)
chr7_-_38659477 0.38 ENSDART00000138071
npsn
nephrosin
chr10_+_20128267 0.38 ENSDART00000064615
dmtn
dematin actin binding protein
chr6_+_55032439 0.36 ENSDART00000164232
ENSDART00000158845
ENSDART00000157584
ENSDART00000026359
ENSDART00000122794
ENSDART00000183742
mybphb
myosin binding protein Hb
chr4_+_21129752 0.36 ENSDART00000169764
syt1a
synaptotagmin Ia
chr10_-_43540196 0.36 ENSDART00000170891
si:ch73-215f7.1
si:ch73-215f7.1
chr4_-_16354292 0.36 ENSDART00000139919
lum
lumican
chr7_+_31879986 0.35 ENSDART00000138491
mybpc3
myosin binding protein C, cardiac
chr13_-_31441042 0.35 ENSDART00000076571
rtn1a
reticulon 1a
chr10_+_21730585 0.34 ENSDART00000188576
pcdh1g22
protocadherin 1 gamma 22
chr1_-_46981134 0.34 ENSDART00000130607
pknox1.2
pbx/knotted 1 homeobox 1.2
chr5_-_51619262 0.33 ENSDART00000134606
ENSDART00000081249
otpb
orthopedia homeobox b
chr22_+_28446365 0.33 ENSDART00000189359
abi3bpb
ABI family, member 3 (NESH) binding protein b
chr8_+_26859639 0.32 ENSDART00000133440
prdm2a
PR domain containing 2, with ZNF domain a
chr10_-_8053753 0.32 ENSDART00000162289
si:ch211-251f6.7
si:ch211-251f6.7
chr23_-_24263474 0.32 ENSDART00000160312
hspb7
heat shock protein family, member 7 (cardiovascular)
chr4_-_27301356 0.32 ENSDART00000100444
fam19a5a
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr4_-_16353733 0.31 ENSDART00000186785
lum
lumican
chr14_-_24761132 0.31 ENSDART00000146299
slit3
slit homolog 3 (Drosophila)
chr16_+_28270037 0.31 ENSDART00000059035
mindy3
MINDY lysine 48 deubiquitinase 3
chr6_+_7444899 0.31 ENSDART00000053775
arf3b
ADP-ribosylation factor 3b
chr9_-_6380653 0.31 ENSDART00000078523
ecrg4a
esophageal cancer related gene 4a
chr22_+_28446557 0.30 ENSDART00000089546
abi3bpb
ABI family, member 3 (NESH) binding protein b
chr8_+_32402441 0.30 ENSDART00000191451
epgn
epithelial mitogen homolog (mouse)
chr10_+_37145007 0.30 ENSDART00000131777
cuedc1a
CUE domain containing 1a
chr9_-_9992697 0.30 ENSDART00000123415
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr1_-_23157583 0.30 ENSDART00000144208
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr21_+_39100289 0.30 ENSDART00000075958
slc13a2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr16_+_50289916 0.30 ENSDART00000168861
ENSDART00000167332
hamp
hepcidin antimicrobial peptide
chr17_+_23300827 0.29 ENSDART00000058745
zgc:165461
zgc:165461
chr6_+_41186320 0.29 ENSDART00000025241
opn1mw2
opsin 1 (cone pigments), medium-wave-sensitive, 2
chr21_-_26089964 0.29 ENSDART00000027848
tlcd1
TLC domain containing 1
chr7_-_69853453 0.28 ENSDART00000049928
myoz2a
myozenin 2a
chr6_-_11768198 0.28 ENSDART00000183463
march7
membrane-associated ring finger (C3HC4) 7
chr21_-_43015383 0.28 ENSDART00000065097
dpysl3
dihydropyrimidinase-like 3
chr13_-_44285793 0.28 ENSDART00000167383
CABZ01069436.1

chr9_+_33009284 0.27 ENSDART00000036926
vangl1
VANGL planar cell polarity protein 1
chr21_-_27338639 0.27 ENSDART00000130632
hif1al2
hypoxia-inducible factor 1, alpha subunit, like 2
chr20_-_20821783 0.27 ENSDART00000152577
ENSDART00000027603
ENSDART00000145601
ckbb
creatine kinase, brain b
chr16_+_46111849 0.26 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr24_+_38301080 0.26 ENSDART00000105672
mybpc2b
myosin binding protein C, fast type b
chr9_-_47472998 0.25 ENSDART00000134480
tns1b
tensin 1b
chr10_-_11385155 0.25 ENSDART00000064214
plac8.1
placenta-specific 8, tandem duplicate 1
chr20_-_29418620 0.25 ENSDART00000172634
ryr3
ryanodine receptor 3
chr5_-_51619742 0.25 ENSDART00000188537
otpb
orthopedia homeobox b
chr8_+_3405612 0.25 ENSDART00000163437
zgc:112433
zgc:112433
chr7_-_38634845 0.25 ENSDART00000173861
c1qtnf4
C1q and TNF related 4
chr8_+_21229718 0.25 ENSDART00000100222
cry1ba
cryptochrome circadian clock 1ba
chr7_-_52950123 0.24 ENSDART00000009649
tubgcp4
tubulin, gamma complex associated protein 4
chr2_-_3437862 0.24 ENSDART00000053012
cyp8b1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr19_+_42983613 0.24 ENSDART00000033724
fabp3
fatty acid binding protein 3, muscle and heart
chr17_-_20717845 0.24 ENSDART00000150037
ank3b
ankyrin 3b
chr18_+_808911 0.23 ENSDART00000172518
cox5ab
cytochrome c oxidase subunit Vab
chr1_-_18803919 0.23 ENSDART00000020970
pgm2
phosphoglucomutase 2
chr7_-_30082931 0.23 ENSDART00000075600
tspan3b
tetraspanin 3b
chr16_+_12836143 0.23 ENSDART00000067741
cacng6b
calcium channel, voltage-dependent, gamma subunit 6b
chr2_+_16846772 0.23 ENSDART00000183564
ENSDART00000126718
fam131a
family with sequence similarity 131, member A
chr10_-_35410518 0.23 ENSDART00000048430
gabrr3a
gamma-aminobutyric acid (GABA) A receptor, rho 3a
chr4_+_10017049 0.23 ENSDART00000144175
ccdc136b
coiled-coil domain containing 136b
chr19_-_31042570 0.23 ENSDART00000144337
ENSDART00000136213
ENSDART00000133101
ENSDART00000190949
bzw2
basic leucine zipper and W2 domains 2
chr17_+_51262556 0.23 ENSDART00000186748
ENSDART00000181606
ENSDART00000063738
ENSDART00000189066
eipr1
EARP complex and GARP complex interacting protein 1
chr11_-_26832685 0.23 ENSDART00000153519
iqsec1b
IQ motif and Sec7 domain 1b
chr23_-_31506854 0.23 ENSDART00000131352
ENSDART00000138625
ENSDART00000133002
eya4
EYA transcriptional coactivator and phosphatase 4
chr3_+_34821327 0.22 ENSDART00000055262
cdk5r1a
cyclin-dependent kinase 5, regulatory subunit 1a (p35)
chr12_-_4346085 0.22 ENSDART00000112433
ca15c
carbonic anhydrase XV c
chr25_-_3830272 0.22 ENSDART00000055843
cd151
CD151 molecule
chr25_-_7999756 0.22 ENSDART00000159908
camk1db
calcium/calmodulin-dependent protein kinase 1Db
chr3_-_24980067 0.22 ENSDART00000048871
desi1a
desumoylating isopeptidase 1a
chr11_-_40147032 0.22 ENSDART00000052918
si:dkey-264d12.4
si:dkey-264d12.4
chr14_-_31893996 0.21 ENSDART00000173222
gpr101
G protein-coupled receptor 101
chr5_-_55395384 0.21 ENSDART00000147298
ENSDART00000082577
prune2
prune homolog 2 (Drosophila)
chr12_+_22404108 0.21 ENSDART00000153055
hdlbpb
high density lipoprotein binding protein b
chr13_+_13681681 0.21 ENSDART00000057825
cfd
complement factor D (adipsin)
chr12_-_4540564 0.21 ENSDART00000106566
CABZ01030107.1

chr19_+_47290287 0.20 ENSDART00000078382
tpmt.1
thiopurine S-methyltransferase, tandem duplicate 1
chr7_+_69841017 0.20 ENSDART00000169107
FO818704.1

chr20_-_32110882 0.20 ENSDART00000030324
grm1a
glutamate receptor, metabotropic 1a
chr16_-_32013913 0.20 ENSDART00000030282
ENSDART00000138701
gstk1
glutathione S-transferase kappa 1
chr2_+_6926100 0.20 ENSDART00000153289
nos1apb
nitric oxide synthase 1 (neuronal) adaptor protein b
chr7_+_48761646 0.20 ENSDART00000017467
acana
aggrecan a
chr17_-_52587598 0.20 ENSDART00000061497
si:ch211-173a9.6
si:ch211-173a9.6
chr8_-_30424182 0.20 ENSDART00000099021
dock8
dedicator of cytokinesis 8
chr21_-_25685739 0.20 ENSDART00000129619
ENSDART00000101205
phkg1b
phosphorylase kinase, gamma 1b (muscle)
chr2_+_34767171 0.20 ENSDART00000145451
astn1
astrotactin 1
chr21_-_28920245 0.20 ENSDART00000132884
cxxc5a
CXXC finger protein 5a
chr7_-_24047316 0.20 ENSDART00000184799
dhrs4
dehydrogenase/reductase (SDR family) member 4
chr7_+_30779761 0.19 ENSDART00000066806
ENSDART00000173671
mcee
methylmalonyl CoA epimerase
chr8_-_53198154 0.19 ENSDART00000083416
gabrd
gamma-aminobutyric acid (GABA) A receptor, delta
chr1_+_40023640 0.19 ENSDART00000101623
lgi2b
leucine-rich repeat LGI family, member 2b
chr5_+_26686279 0.19 ENSDART00000193543
tango2
transport and golgi organization 2 homolog (Drosophila)
chr14_+_45675306 0.19 ENSDART00000105461
rom1b
retinal outer segment membrane protein 1b
chr10_+_21650828 0.19 ENSDART00000160754
pcdh1g1
protocadherin 1 gamma 1
chr13_+_19884631 0.19 ENSDART00000089533
atrnl1a
attractin-like 1a
chr1_+_46194333 0.19 ENSDART00000010894
sox1b
SRY (sex determining region Y)-box 1b
chr13_-_43599898 0.19 ENSDART00000084416
ENSDART00000145705
ablim1a
actin binding LIM protein 1a
chr18_-_42172101 0.19 ENSDART00000124211
cntn5
contactin 5
chr13_+_844150 0.19 ENSDART00000058260
gsta.1
glutathione S-transferase, alpha tandem duplicate 1
chr7_+_53755054 0.19 ENSDART00000181629
neo1a
neogenin 1a
chr5_+_9382301 0.18 ENSDART00000124017
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr15_+_8043751 0.18 ENSDART00000193701
cadm2b
cell adhesion molecule 2b
chr10_+_21722892 0.18 ENSDART00000162855
pcdh1g13
protocadherin 1 gamma 13
chr1_+_1805294 0.18 ENSDART00000103850
atp1a1a.3
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 3
chr1_-_681116 0.18 ENSDART00000165894
adamts1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr19_+_43439457 0.18 ENSDART00000151571
ahdc1
AT hook, DNA binding motif, containing 1
chr16_-_29452039 0.18 ENSDART00000148960
si:ch211-113g11.6
si:ch211-113g11.6
chr10_-_8053385 0.18 ENSDART00000142714
si:ch211-251f6.7
si:ch211-251f6.7
chr11_-_141592 0.18 ENSDART00000092787
cdk4
cyclin-dependent kinase 4
chr15_-_18176694 0.18 ENSDART00000189840
tmprss5
transmembrane protease, serine 5
chr5_+_9377005 0.18 ENSDART00000124924
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr2_-_18830722 0.18 ENSDART00000165330
ENSDART00000165698
pbx1a
pre-B-cell leukemia homeobox 1a
chr12_+_18681477 0.18 ENSDART00000127981
ENSDART00000143979
rgs9b
regulator of G protein signaling 9b
chr11_+_141504 0.18 ENSDART00000086166
NCKAP1L
zgc:172352
chr18_+_21122818 0.17 ENSDART00000060015
ENSDART00000060184
chka
choline kinase alpha
chr16_-_8251985 0.17 ENSDART00000109302
fam198a
family with sequence similarity 198, member A
chr8_-_34065573 0.17 ENSDART00000186946
pbx3b
pre-B-cell leukemia homeobox 3b
chr13_+_25380432 0.17 ENSDART00000038524
gsto1
glutathione S-transferase omega 1
chr14_+_35024521 0.17 ENSDART00000158634
ENSDART00000170631
ebf3a
early B cell factor 3a
chr23_-_20051369 0.17 ENSDART00000049836
bgnb
biglycan b
chr13_+_24834199 0.17 ENSDART00000101274
zgc:153981
zgc:153981
chr21_+_11969603 0.17 ENSDART00000142247
ENSDART00000140652
mlnl
motilin-like
chr10_-_19801821 0.17 ENSDART00000148013
gfra2b
GDNF family receptor alpha 2b
chr4_-_13255700 0.17 ENSDART00000162277
ENSDART00000026593
grip1
glutamate receptor interacting protein 1
chr10_+_26571174 0.17 ENSDART00000148617
ENSDART00000112956
slc9a6b
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6b
chr18_-_48508585 0.17 ENSDART00000133364
kcnj1a.4
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 4
chr5_-_55395964 0.17 ENSDART00000145791
prune2
prune homolog 2 (Drosophila)
chr25_+_32473277 0.17 ENSDART00000146451
sqor
sulfide quinone oxidoreductase
chr11_+_42730639 0.16 ENSDART00000165297
zgc:194981
zgc:194981
chr18_-_48517040 0.16 ENSDART00000143645
kcnj1a.3
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 3
chr15_-_452347 0.16 ENSDART00000115233
VSTM5
V-set and transmembrane domain containing 5
chr22_-_31517300 0.16 ENSDART00000164799
slc6a6b
solute carrier family 6 (neurotransmitter transporter), member 6b
chr16_-_37372613 0.16 ENSDART00000124090
si:ch211-208k15.1
si:ch211-208k15.1
chr8_-_2616326 0.16 ENSDART00000027214
slc25a25a
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a
chr6_+_21095918 0.16 ENSDART00000167225
spega
SPEG complex locus a
chr5_+_2815021 0.16 ENSDART00000020472
hpda
4-hydroxyphenylpyruvate dioxygenase a
chr18_+_13792490 0.16 ENSDART00000136754
cdh13
cadherin 13, H-cadherin (heart)
chr17_+_15788100 0.16 ENSDART00000027667
rragd
ras-related GTP binding D
chr23_+_799100 0.16 ENSDART00000084373
frmd4bb
FERM domain containing 4Bb
chr11_-_25775447 0.16 ENSDART00000161301
plch2b
phospholipase C, eta 2b
chr9_-_2573121 0.16 ENSDART00000181340
scrn3
secernin 3
chr10_-_8046764 0.16 ENSDART00000099031
zgc:136254
zgc:136254
chr12_-_30558694 0.16 ENSDART00000153417
si:ch211-28p3.3
si:ch211-28p3.3
chr1_-_39943596 0.16 ENSDART00000149730
stox2a
storkhead box 2a
chr18_+_3004572 0.15 ENSDART00000190328
CABZ01002690.1

chr19_+_32321797 0.15 ENSDART00000167664
atxn1a
ataxin 1a
chr5_-_71838520 0.15 ENSDART00000174396
CU927890.1

chr18_+_11858397 0.15 ENSDART00000133762
tmtc2b
transmembrane and tetratricopeptide repeat containing 2b
chr12_+_27213733 0.15 ENSDART00000133048
nbr1a
neighbor of brca1 gene 1a
chr13_-_8692432 0.15 ENSDART00000058106
mcfd2
multiple coagulation factor deficiency 2
chr5_-_29238889 0.14 ENSDART00000143098
si:dkey-61l1.4
si:dkey-61l1.4
chr16_+_37891735 0.14 ENSDART00000178753
ENSDART00000142104
cep162
centrosomal protein 162
chr6_-_51101834 0.14 ENSDART00000092493
ptprt
protein tyrosine phosphatase, receptor type, t
chr17_-_19626357 0.14 ENSDART00000011432
reep3a
receptor accessory protein 3a
chr23_+_11669337 0.14 ENSDART00000131355
cntn3a.1
contactin 3a, tandem duplicate 1
chr11_-_44030962 0.14 ENSDART00000171910
FP016005.1

chr9_-_2572790 0.14 ENSDART00000135076
ENSDART00000016710
scrn3
secernin 3
chr15_-_1822166 0.14 ENSDART00000156883
mmp28
matrix metallopeptidase 28
chr25_-_13842618 0.13 ENSDART00000160258
mapk8ip1a
mitogen-activated protein kinase 8 interacting protein 1a
chr11_+_44356707 0.13 ENSDART00000165219
srsf7b
serine/arginine-rich splicing factor 7b
chr8_-_38159805 0.13 ENSDART00000112331
ENSDART00000180006
adgra2
adhesion G protein-coupled receptor A2
chr23_+_40951443 0.13 ENSDART00000115161
reps2
RALBP1 associated Eps domain containing 2
chr4_-_18635005 0.13 ENSDART00000125361
pparaa
peroxisome proliferator-activated receptor alpha a
chr9_+_13714379 0.13 ENSDART00000017593
ENSDART00000145503
tmem237a
transmembrane protein 237a
chr6_-_29105727 0.13 ENSDART00000184355
fam69ab
family with sequence similarity 69, member Ab
chr1_+_52929185 0.13 ENSDART00000147683
inpp4b
inositol polyphosphate-4-phosphatase type II B
chr16_-_17175731 0.13 ENSDART00000183057
opn9
opsin 9
chr16_+_33655890 0.13 ENSDART00000143757
fhl3a
four and a half LIM domains 3a
chr2_-_37797577 0.13 ENSDART00000110781
nfatc4
nuclear factor of activated T cells 4
chr5_-_62940851 0.13 ENSDART00000137052
specc1
sperm antigen with calponin homology and coiled-coil domains 1

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa9a+hoxa9b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 0.3 GO:0070314 G1 to G0 transition(GO:0070314)
0.1 0.4 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 0.6 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.1 0.6 GO:0021767 mammillary body development(GO:0021767)
0.1 0.3 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 0.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.3 GO:0055091 phospholipid homeostasis(GO:0055091)
0.1 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.1 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.1 0.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.3 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.0 0.2 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.2 GO:0031649 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.3 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.8 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.3 GO:0032570 response to progesterone(GO:0032570)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.7 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.7 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.2 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.4 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.3 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.7 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:2000425 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176) regulation of apoptotic cell clearance(GO:2000425)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.1 GO:0019364 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.0 0.2 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.0 0.5 GO:0016203 muscle attachment(GO:0016203)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.6 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.1 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.7 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.0 0.1 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 0.1 GO:0045687 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.3 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0036076 ligamentous ossification(GO:0036076)
0.0 0.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.2 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.8 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.1 GO:0003262 endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.0 0.1 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.7 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.3 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.1 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.2 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.1 GO:0035777 pronephric distal tubule development(GO:0035777)
0.0 0.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.0 GO:0015677 copper ion import(GO:0015677)
0.0 0.1 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0 0.2 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.0 GO:0090085 regulation of protein deubiquitination(GO:0090085) positive regulation of protein deubiquitination(GO:1903003)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.4 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.7 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.3 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.1 GO:0097541 axonemal basal plate(GO:0097541)
0.0 0.5 GO:0046930 pore complex(GO:0046930)
0.0 0.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.5 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 1.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0005861 troponin complex(GO:0005861)
0.0 1.2 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.0 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 0.6 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.7 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.3 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.1 0.9 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 0.2 GO:0008397 sterol 12-alpha-hydroxylase activity(GO:0008397)
0.1 0.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.2 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.1 0.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.4 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.3 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 0.2 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672)
0.1 0.2 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.1 0.3 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.4 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.1 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.0 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions