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PRJNA195909:zebrafish embryo and larva development

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Results for hoxb10a+hoxc10a

Z-value: 0.62

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Transcription factors associated with hoxb10a+hoxc10a

Gene Symbol Gene ID Gene Info
hoxb10a
ENSDARG00000011579 homeobox B10a
hoxc10a
ENSDARG00000070348 homeobox C10a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxb10adr11_v1_chr3_+_23669267_236692670.909.0e-04Click!
hoxc10adr11_v1_chr23_+_36083529_360836170.853.7e-03Click!

Activity profile of hoxb10a+hoxc10a motif

Sorted Z-values of hoxb10a+hoxc10a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_+_10146542 1.58 ENSDART00000048073
zgc:171775
zgc:171775
chr3_-_31804481 1.46 ENSDART00000028270
gfap
glial fibrillary acidic protein
chr23_+_27068225 1.41 ENSDART00000054238
mipa
major intrinsic protein of lens fiber a
chr16_-_45917322 1.19 ENSDART00000060822
afp4
antifreeze protein type IV
chr2_+_2223837 1.17 ENSDART00000101038
ENSDART00000129354
tmie
transmembrane inner ear
chr25_+_20089986 1.15 ENSDART00000143441
ENSDART00000184073
tnni4b.2
troponin I4b, tandem duplicate 2
chr6_+_52790049 1.15 ENSDART00000002571
matn4
matrilin 4
chr2_-_35566938 1.09 ENSDART00000029006
ENSDART00000077178
ENSDART00000125298
tnn
tenascin N
chr23_+_39606108 1.09 ENSDART00000109464
g0s2
G0/G1 switch 2
chr10_-_29903165 1.01 ENSDART00000078800
lim2.1
lens intrinsic membrane protein 2.1
chr1_-_38195012 0.92 ENSDART00000020409
hand2
heart and neural crest derivatives expressed 2
chr12_+_27117609 0.88 ENSDART00000076154
hoxb8b
homeobox B8b
chr19_-_15855427 0.86 ENSDART00000133059
cited4a
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a
chr25_-_31423493 0.80 ENSDART00000027661
myod1
myogenic differentiation 1
chr6_-_60147517 0.80 ENSDART00000083453
slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr13_+_22264914 0.78 ENSDART00000060576
myoz1a
myozenin 1a
chr20_+_26538137 0.76 ENSDART00000045397
stx11b.1
syntaxin 11b, tandem duplicate 1
chr9_-_1939232 0.76 ENSDART00000146131
hoxd3a
homeobox D3a
chr6_+_35362225 0.74 ENSDART00000133783
ENSDART00000102483
rgs4
regulator of G protein signaling 4
chr16_+_50969248 0.74 ENSDART00000172068
si:dkeyp-97a10.2
si:dkeyp-97a10.2
chr12_-_20373058 0.72 ENSDART00000066382
aqp8a.1
aquaporin 8a, tandem duplicate 1
chr19_+_19762183 0.71 ENSDART00000163611
ENSDART00000187604
hoxa3a
homeobox A3a
chr19_+_17385561 0.69 ENSDART00000141397
ENSDART00000143913
ENSDART00000133626
rpl15
ribosomal protein L15
chr18_+_19974289 0.67 ENSDART00000090334
ENSDART00000192982
skor1b
SKI family transcriptional corepressor 1b
chr14_+_30279391 0.66 ENSDART00000172794
fgl1
fibrinogen-like 1
chr7_+_60111581 0.62 ENSDART00000087093
hspa12b
heat shock protein 12B
chr22_-_4644484 0.60 ENSDART00000167748
fbn2b
fibrillin 2b
chr12_+_5081759 0.60 ENSDART00000164178
prrt2
proline-rich transmembrane protein 2
chr10_+_36650222 0.59 ENSDART00000126963
ucp3
uncoupling protein 3
chr24_-_27473771 0.57 ENSDART00000139874
cxl34b.11
CX chemokine ligand 34b, duplicate 11
chr6_+_27624023 0.56 ENSDART00000147789
slco2a1
solute carrier organic anion transporter family, member 2A1
chr17_+_33453689 0.56 ENSDART00000156894
rin3
Ras and Rab interactor 3
chr11_+_30244356 0.55 ENSDART00000036050
ENSDART00000150080
rs1a
retinoschisin 1a
chr20_+_52546186 0.53 ENSDART00000110777
ENSDART00000153377
ENSDART00000153013
ENSDART00000042704
eef1db
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr5_+_15202495 0.50 ENSDART00000144915
tbx1
T-box 1
chr19_-_14191592 0.50 ENSDART00000164594
tbxta
T-box transcription factor Ta
chr11_+_36158134 0.48 ENSDART00000189827
ENSDART00000163330
grm2b
glutamate receptor, metabotropic 2b
chr4_+_5741733 0.48 ENSDART00000110243
pou3f2a
POU class 3 homeobox 2a
chr19_-_10881486 0.48 ENSDART00000168852
ENSDART00000160438
PSMD4 (1 of many)
psmd4a
proteasome 26S subunit, non-ATPase 4
proteasome 26S subunit, non-ATPase 4a
chr11_-_18253111 0.46 ENSDART00000125984
mustn1b
musculoskeletal, embryonic nuclear protein 1b
chr23_+_25354856 0.45 ENSDART00000109023
ENSDART00000147440
fmnl3
formin-like 3
chr19_+_19761966 0.45 ENSDART00000163697
hoxa3a
homeobox A3a
chr21_-_25756119 0.44 ENSDART00000002341
cldnc
claudin c
chr7_+_25059845 0.42 ENSDART00000077215
ppp2r5b
protein phosphatase 2, regulatory subunit B', beta
chr14_+_22114918 0.39 ENSDART00000166610
tmx2a
thioredoxin-related transmembrane protein 2a
chr7_+_30875273 0.39 ENSDART00000173693
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr13_-_50108337 0.39 ENSDART00000133308
nid1a
nidogen 1a
chr16_-_7443388 0.39 ENSDART00000017445
prdm1a
PR domain containing 1a, with ZNF domain
chr9_-_32753535 0.38 ENSDART00000060006
olig2
oligodendrocyte lineage transcription factor 2
chr4_+_37406676 0.37 ENSDART00000130981
si:ch73-134f24.1
si:ch73-134f24.1
chr5_-_48307804 0.37 ENSDART00000182831
ENSDART00000186920
ENSDART00000183585
mef2cb
myocyte enhancer factor 2cb
chr24_+_12913329 0.35 ENSDART00000141829
si:dkeyp-28d2.4
si:dkeyp-28d2.4
chr1_-_35924495 0.35 ENSDART00000184424
smad1
SMAD family member 1
chr13_-_42749916 0.34 ENSDART00000140019
capn2a
calpain 2, (m/II) large subunit a
chr2_+_52847049 0.33 ENSDART00000121980
creb3l3b
cAMP responsive element binding protein 3-like 3b
chr24_-_8732519 0.32 ENSDART00000082351
tfap2a
transcription factor AP-2 alpha
chr25_-_13614863 0.31 ENSDART00000121859
fa2h
fatty acid 2-hydroxylase
chr13_+_31108334 0.31 ENSDART00000142245
arhgap22
Rho GTPase activating protein 22
chr8_+_18588551 0.31 ENSDART00000177476
ENSDART00000063539
prrg1
proline rich Gla (G-carboxyglutamic acid) 1
chr8_-_25120231 0.30 ENSDART00000147308
amigo1
adhesion molecule with Ig-like domain 1
chr11_-_2700397 0.30 ENSDART00000082511
si:ch211-160o17.6
si:ch211-160o17.6
chr5_-_26181863 0.30 ENSDART00000098500
ccdc125
coiled-coil domain containing 125
chr19_+_4916233 0.30 ENSDART00000159512
ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr10_-_22845485 0.30 ENSDART00000079454
vamp2
vesicle-associated membrane protein 2
chr2_+_20406399 0.28 ENSDART00000006817
ENSDART00000137848
palmda
palmdelphin a
chr9_-_41784799 0.28 ENSDART00000144573
ENSDART00000112542
ENSDART00000190486
obsl1b
obscurin-like 1b
chr7_-_69025306 0.27 ENSDART00000180796
CABZ01057488.2

chr17_-_12389259 0.27 ENSDART00000185724
snap25b
synaptosomal-associated protein, 25b
chr19_-_10881141 0.27 ENSDART00000162793
psmd4a
proteasome 26S subunit, non-ATPase 4a
chr19_-_17385548 0.26 ENSDART00000162383
nkiras1
NFKB inhibitor interacting Ras-like 1
chr11_-_6265574 0.24 ENSDART00000181974
ENSDART00000104405
ccl25b
chemokine (C-C motif) ligand 25b
chr2_-_6039757 0.24 ENSDART00000013079
scp2a
sterol carrier protein 2a
chr16_+_46459680 0.23 ENSDART00000101698
rpz3
rapunzel 3
chr13_-_37519774 0.23 ENSDART00000141420
ENSDART00000185478
sgpp1
sphingosine-1-phosphate phosphatase 1
chr10_+_26612321 0.22 ENSDART00000134322
fhl1b
four and a half LIM domains 1b
chr3_+_24134418 0.22 ENSDART00000156204
si:ch211-246i5.5
si:ch211-246i5.5
chr7_+_48761875 0.21 ENSDART00000003690
acana
aggrecan a
chr5_+_24245682 0.21 ENSDART00000049003
atp6v1aa
ATPase H+ transporting V1 subunit Aa
chr8_+_2487250 0.21 ENSDART00000081325
dynll1
dynein, light chain, LC8-type 1
chr24_+_1042594 0.20 ENSDART00000109117
si:dkey-192l18.9
si:dkey-192l18.9
chr4_-_56898328 0.20 ENSDART00000169189
si:dkey-269o24.6
si:dkey-269o24.6
chr13_+_36585399 0.20 ENSDART00000030211
gmfb
glia maturation factor, beta
chr8_+_2487883 0.20 ENSDART00000101841
dynll1
dynein, light chain, LC8-type 1
chr1_+_40801448 0.19 ENSDART00000187394
cpz
carboxypeptidase Z
chr12_-_26430507 0.19 ENSDART00000153214
synpo2lb
synaptopodin 2-like b
chr7_-_45076131 0.19 ENSDART00000110590
zgc:194678
zgc:194678
chr14_-_30967284 0.18 ENSDART00000149435
il2rgb
interleukin 2 receptor, gamma b
chr5_+_26913120 0.18 ENSDART00000126609
tbx3b
T-box 3b
chr5_-_24174956 0.18 ENSDART00000137631
si:ch211-137i24.10
si:ch211-137i24.10
chr10_+_2587234 0.18 ENSDART00000126937
wu:fb59d01
wu:fb59d01
chr9_+_30720048 0.18 ENSDART00000146115
klf12b
Kruppel-like factor 12b
chr10_-_34772211 0.18 ENSDART00000145450
ENSDART00000134307
dclk1a
doublecortin-like kinase 1a
chr15_+_37559570 0.17 ENSDART00000085522
hspb6
heat shock protein, alpha-crystallin-related, b6
chr4_+_7391400 0.17 ENSDART00000169111
ENSDART00000186395
tnni4a
troponin I4a
chr16_+_25535993 0.16 ENSDART00000077436
mylipb
myosin regulatory light chain interacting protein b
chr18_-_15559817 0.16 ENSDART00000061681
si:ch211-245j22.3
si:ch211-245j22.3
chr6_-_19683406 0.15 ENSDART00000158041
cfap52
cilia and flagella associated protein 52
chr24_-_12689571 0.15 ENSDART00000015517
pdcd6
programmed cell death 6
chr9_+_41024973 0.15 ENSDART00000014660
ENSDART00000144467
ormdl1
ORMDL sphingolipid biosynthesis regulator 1
chr7_-_26457208 0.15 ENSDART00000173519
zgc:172079
zgc:172079
chr16_+_13883872 0.14 ENSDART00000101304
ENSDART00000136005
atg12
ATG12 autophagy related 12 homolog (S. cerevisiae)
chr7_-_29341233 0.14 ENSDART00000140938
ENSDART00000147251
trpm1a
transient receptor potential cation channel, subfamily M, member 1a
chr11_+_14284866 0.14 ENSDART00000163729
si:ch211-262i1.3
si:ch211-262i1.3
chr6_+_13083146 0.14 ENSDART00000172158
l3hypdh
trans-L-3-hydroxyproline dehydratase
chr23_-_27571667 0.14 ENSDART00000008174
pfkma
phosphofructokinase, muscle a
chr24_-_31846366 0.13 ENSDART00000155295
steap2
STEAP family member 2, metalloreductase
chr20_+_9763364 0.13 ENSDART00000053834
psmc6
proteasome 26S subunit, ATPase 6
chr7_-_41338923 0.13 ENSDART00000099138
ncf2
neutrophil cytosolic factor 2
chr2_+_5927255 0.12 ENSDART00000152866
si:ch211-168b3.2
si:ch211-168b3.2
chr8_+_30709685 0.12 ENSDART00000133989
upb1
ureidopropionase, beta
chr20_+_46183505 0.12 ENSDART00000060799
taar13b
trace amine associated receptor 13b
chr21_-_21537452 0.12 ENSDART00000142549
or133-7
odorant receptor, family H, subfamily 133, member 7
chr23_+_7379728 0.12 ENSDART00000012194
gata5
GATA binding protein 5
chr11_+_2699951 0.11 ENSDART00000082512
tmem167b
transmembrane protein 167B
chr19_+_42469058 0.11 ENSDART00000076915
si:dkey-166k12.1
si:dkey-166k12.1
chr20_+_6543674 0.11 ENSDART00000134204
tns3.1
tensin 3, tandem duplicate 1
chr4_+_7391110 0.11 ENSDART00000160708
ENSDART00000187823
tnni4a
troponin I4a
chr19_+_19599528 0.11 ENSDART00000163054
hibadha
3-hydroxyisobutyrate dehydrogenase a
chr2_+_21855291 0.10 ENSDART00000186204
ca8
carbonic anhydrase VIII
chr20_+_27464721 0.10 ENSDART00000189552
kif26aa
kinesin family member 26Aa
chr18_+_7363242 0.10 ENSDART00000133375
si:dkey-30c15.17
si:dkey-30c15.17
chr17_+_45395846 0.10 ENSDART00000058793
nenf
neudesin neurotrophic factor
chr10_+_40606084 0.10 ENSDART00000133119
si:ch211-238p8.24
si:ch211-238p8.24
chr12_+_34051848 0.10 ENSDART00000153276
cyth1b
cytohesin 1b
chr4_+_2267641 0.10 ENSDART00000165503
si:ch73-89b15.3
si:ch73-89b15.3
chr21_-_21594841 0.10 ENSDART00000132490
or133-2
odorant receptor, family H, subfamily 133, member 2
chr22_+_25331766 0.10 ENSDART00000155006
ENSDART00000155836
si:ch211-226h8.15
si:ch211-226h8.15
chr25_-_10907786 0.10 ENSDART00000172490
CR339041.1

chr1_+_51407520 0.10 ENSDART00000074294
actr2a
ARP2 actin related protein 2a homolog
chr23_+_24085531 0.10 ENSDART00000139710
ttll10
tubulin tyrosine ligase-like family, member 10
chr24_-_27452488 0.10 ENSDART00000136433
ccl34b.8
chemokine (C-C motif) ligand 34b, duplicate 8
chr2_+_35595454 0.10 ENSDART00000098734
cacybp
calcyclin binding protein
chr6_+_30703828 0.09 ENSDART00000104628
insl5a
insulin-like 5a
chr16_-_2558653 0.09 ENSDART00000110365
adcy3a
adenylate cyclase 3a
chr21_-_20328375 0.08 ENSDART00000079593
slc26a1
solute carrier family 26 (anion exchanger), member 1
chr22_+_18187857 0.08 ENSDART00000166300
mef2b
myocyte enhancer factor 2b
chr19_+_2590182 0.08 ENSDART00000162293
si:ch73-345f18.3
si:ch73-345f18.3
chr6_+_36877968 0.08 ENSDART00000155187
traf3ip2l
TRAF3 interacting protein 2-like
chr16_+_45746549 0.08 ENSDART00000190403
paqr6
progestin and adipoQ receptor family member VI
chr22_+_26853254 0.08 ENSDART00000182487
tmem186
transmembrane protein 186
chr24_-_27461295 0.08 ENSDART00000110748
ccl34b.9
chemokine (C-C motif) ligand 34b, duplicate 9
chr5_+_23136544 0.07 ENSDART00000003428
ENSDART00000109340
ENSDART00000171039
ENSDART00000178821
prps1a
phosphoribosyl pyrophosphate synthetase 1A
chr11_+_36231248 0.07 ENSDART00000131104
GPR62 (1 of many)
si:ch211-213o11.11
chr1_-_37377509 0.07 ENSDART00000113542
tnip2
TNFAIP3 interacting protein 2
chr7_+_24165371 0.07 ENSDART00000173472
si:ch211-216p19.5
si:ch211-216p19.5
chr19_+_5418006 0.07 ENSDART00000132874
eif1b
eukaryotic translation initiation factor 1B
chr24_+_1294176 0.06 ENSDART00000106637
si:ch73-134f24.1
si:ch73-134f24.1
chr6_+_52869892 0.06 ENSDART00000146143
si:dkeyp-3f10.16
si:dkeyp-3f10.16
chr17_+_8184649 0.06 ENSDART00000091818
tulp4b
tubby like protein 4b
chr21_+_4957685 0.06 ENSDART00000144166
B3GNT10
si:ch73-29c22.2
chr8_+_3379815 0.06 ENSDART00000155995
FUT9 (1 of many)
zgc:136963
chr2_-_34072218 0.06 ENSDART00000184618
eif2b3
eukaryotic translation initiation factor 2B, subunit 3 gamma
chr6_-_39653972 0.06 ENSDART00000155859
larp4ab
La ribonucleoprotein domain family, member 4Ab
chr16_-_21038015 0.06 ENSDART00000059239
snx10b
sorting nexin 10b
chr7_-_32599669 0.06 ENSDART00000173752
kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr22_+_18188045 0.05 ENSDART00000140106
mef2b
myocyte enhancer factor 2b
chr12_+_19356623 0.05 ENSDART00000078284
dmc1
DNA meiotic recombinase 1
chr25_-_13614702 0.05 ENSDART00000165510
ENSDART00000190959
fa2h
fatty acid 2-hydroxylase
chr17_-_15747296 0.04 ENSDART00000153970
cx52.7
connexin 52.7
chr10_+_506538 0.04 ENSDART00000141713
si:ch211-242f23.3
si:ch211-242f23.3
chr1_+_1915967 0.03 ENSDART00000131463
si:ch211-132g1.1
si:ch211-132g1.1
chr7_-_17457872 0.03 ENSDART00000191583
ENSDART00000192609
nitr3c
novel immune-type receptor 3c
chr25_-_32449235 0.03 ENSDART00000115343
atp8b4
ATPase phospholipid transporting 8B4
chr16_+_25664078 0.03 ENSDART00000154024
nsmce2
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase
chr18_+_20825375 0.03 ENSDART00000090100
ENSDART00000146751
ENSDART00000141686
ttc23
tetratricopeptide repeat domain 23
chr20_+_46172649 0.03 ENSDART00000111317
taar13e
trace amine associated receptor 13e
chr10_+_40583930 0.03 ENSDART00000134523
taar18j
trace amine associated receptor 18j
chr13_-_50546634 0.03 ENSDART00000192127
CU570781.2

chr16_+_25664387 0.02 ENSDART00000184394
nsmce2
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase
chr7_-_60096318 0.02 ENSDART00000189125
BX511067.1

chr13_-_12660318 0.02 ENSDART00000008498
adh8a
alcohol dehydrogenase 8a
chr15_-_28860282 0.02 ENSDART00000156738
gpr4
G protein-coupled receptor 4
chr17_-_15746898 0.02 ENSDART00000180079
cx52.7
connexin 52.7
chr8_-_19487327 0.02 ENSDART00000111710
edem3
ER degradation enhancer, mannosidase alpha-like 3
chr2_+_21855036 0.02 ENSDART00000140012
ca8
carbonic anhydrase VIII
chr17_+_33226955 0.02 ENSDART00000063333
pomca
proopiomelanocortin a
chr12_+_19191787 0.02 ENSDART00000152892
slc16a8
solute carrier family 16 (monocarboxylate transporter), member 8
chr9_+_27339505 0.01 ENSDART00000011822
slc10a2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr7_+_27317174 0.01 ENSDART00000193058
sox6
SRY (sex determining region Y)-box 6
chr11_+_36683859 0.01 ENSDART00000170102
si:ch211-11c3.12
si:ch211-11c3.12
chr23_-_24047054 0.01 ENSDART00000184308
ENSDART00000185902
CR925720.1

chr22_-_8594846 0.01 ENSDART00000081690
ENSDART00000192241
si:ch73-27e22.1
si:ch73-27e22.1
chr17_-_47090440 0.01 ENSDART00000163542
CABZ01056321.1

chr4_+_51552434 0.00 ENSDART00000165016
si:dkey-165e24.1
si:dkey-165e24.1

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxb10a+hoxc10a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.2 0.5 GO:0043282 pharyngeal muscle development(GO:0043282)
0.2 0.6 GO:0061323 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart morphogenesis(GO:0061323) regulation of cell proliferation involved in heart morphogenesis(GO:2000136) cell proliferation involved in heart valve development(GO:2000793)
0.2 0.9 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.2 1.2 GO:0060017 parathyroid gland development(GO:0060017)
0.2 1.4 GO:0006833 water transport(GO:0006833)
0.1 0.5 GO:0072045 convergent extension involved in nephron morphogenesis(GO:0072045)
0.1 0.8 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 0.4 GO:0021742 abducens nucleus development(GO:0021742)
0.1 0.5 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 0.2 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.1 0.6 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.4 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 1.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.7 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0032370 positive regulation of lipid transport(GO:0032370)
0.0 0.1 GO:0045730 respiratory burst(GO:0045730)
0.0 0.4 GO:0001709 cell fate determination(GO:0001709)
0.0 1.2 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.1 GO:2000303 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.2 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.0 0.6 GO:0071715 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.0 0.1 GO:0015677 copper ion import(GO:0015677)
0.0 1.0 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.1 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.0 1.4 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.3 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.1 GO:0019483 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.0 0.1 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134) toll-like receptor 3 signaling pathway(GO:0034138)
0.0 0.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.4 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.6 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.7 GO:1903038 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.3 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.4 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0061615 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.0 GO:0042148 strand invasion(GO:0042148)
0.0 0.1 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.6 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 1.5 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.2 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 1.0 GO:0031018 endocrine pancreas development(GO:0031018)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.9 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 0.8 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 1.4 GO:0005861 troponin complex(GO:0005861)
0.0 0.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.5 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 GO:0015250 water channel activity(GO:0015250)
0.1 0.6 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.4 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
0.1 0.8 GO:0070888 E-box binding(GO:0070888)
0.1 0.8 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 0.5 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.8 GO:0015295 solute:proton symporter activity(GO:0015295)
0.1 0.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.2 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.6 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 1.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.0 0.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.4 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.1 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 1.0 GO:0008009 chemokine activity(GO:0008009)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.0 GO:0000150 recombinase activity(GO:0000150)
0.0 0.7 GO:0046332 SMAD binding(GO:0046332)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 2.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 0.8 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 0.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.5 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism