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PRJNA195909:zebrafish embryo and larva development

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Results for hoxb2a

Z-value: 1.21

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Transcription factors associated with hoxb2a

Gene Symbol Gene ID Gene Info
hoxb2a
ENSDARG00000000175 homeobox B2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxb2adr11_v1_chr3_+_23752150_23752150-0.826.8e-03Click!

Activity profile of hoxb2a motif

Sorted Z-values of hoxb2a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_25777425 5.00 ENSDART00000021620
cldnd
claudin d
chr19_-_18313303 3.12 ENSDART00000164644
ENSDART00000167480
ENSDART00000163104
si:dkey-208k4.2
si:dkey-208k4.2
chr18_+_20560616 3.05 ENSDART00000136710
ENSDART00000151974
ENSDART00000121699
ENSDART00000040074
wee2
WEE1 homolog 2 (S. pombe)
chr24_+_1023839 2.97 ENSDART00000082526
zgc:111976
zgc:111976
chr20_-_23426339 2.82 ENSDART00000004625
zar1
zygote arrest 1
chr10_-_44560165 2.62 ENSDART00000181217
ENSDART00000076084
npm2b
nucleophosmin/nucleoplasmin, 2b
chr10_-_21362071 2.42 ENSDART00000125167
avd
avidin
chr10_-_21362320 2.38 ENSDART00000189789
avd
avidin
chr24_-_10014512 2.21 ENSDART00000124341
ENSDART00000191630
zgc:171474
zgc:171474
chr5_-_19006290 2.02 ENSDART00000137022
golga3
golgin A3
chr10_-_25217347 1.99 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr6_+_28208973 1.96 ENSDART00000171216
ENSDART00000171377
ENSDART00000167389
ENSDART00000166988
LSM2 (1 of many)
si:ch73-14h10.2
chr4_-_77125693 1.94 ENSDART00000174256
CU467646.3

chr1_-_18811517 1.74 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr11_-_1550709 1.73 ENSDART00000110097
si:ch73-303b9.1
si:ch73-303b9.1
chr14_-_33481428 1.71 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lamp2
lysosomal-associated membrane protein 2
chr1_-_55248496 1.71 ENSDART00000098615
nanos3
nanos homolog 3
chr16_-_42056137 1.59 ENSDART00000102798
zp3d.2
zona pellucida glycoprotein 3d tandem duplicate 2
chr10_+_6884627 1.57 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr20_-_38787047 1.57 ENSDART00000152913
ENSDART00000153430
dnajc5ga
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a
chr2_+_6253246 1.54 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr20_-_38787341 1.51 ENSDART00000136771
dnajc5ga
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a
chr9_-_38021889 1.47 ENSDART00000183482
ENSDART00000124333
adcy5
adenylate cyclase 5
chr8_+_41037541 1.45 ENSDART00000129344
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr19_+_31585917 1.44 ENSDART00000132182
gmnn
geminin, DNA replication inhibitor
chr21_-_14174786 1.42 ENSDART00000145366
whrna
whirlin a
chr2_-_57076687 1.36 ENSDART00000161523
slc25a42
solute carrier family 25, member 42
chr5_-_26247973 1.34 ENSDART00000098527
erap1b
endoplasmic reticulum aminopeptidase 1b
chr6_-_43283122 1.34 ENSDART00000186022
frmd4ba
FERM domain containing 4Ba
chr5_-_30074332 1.34 ENSDART00000147963
bco2a
beta-carotene oxygenase 2a
chr3_+_26244353 1.33 ENSDART00000103733
atad5a
ATPase family, AAA domain containing 5a
chr9_+_29548195 1.33 ENSDART00000176057
rnf17
ring finger protein 17
chr5_-_16734060 1.31 ENSDART00000035859
ENSDART00000190457
ENSDART00000179244
atad1a
ATPase family, AAA domain containing 1a
chr15_-_16177603 1.31 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr14_+_24845941 1.30 ENSDART00000187513
arhgef37
Rho guanine nucleotide exchange factor (GEF) 37
chr17_+_16046132 1.28 ENSDART00000155005
si:ch73-204p21.2
si:ch73-204p21.2
chr11_+_31864921 1.26 ENSDART00000180252
diaph3
diaphanous-related formin 3
chr14_-_8940499 1.25 ENSDART00000129030
zgc:153681
zgc:153681
chr22_-_22337382 1.25 ENSDART00000144684
si:ch211-129c21.1
si:ch211-129c21.1
chr10_+_6884123 1.24 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr6_-_2134581 1.23 ENSDART00000175478
vstm2l
V-set and transmembrane domain containing 2 like
chr22_+_1170294 1.21 ENSDART00000159761
ENSDART00000169809
irf6
interferon regulatory factor 6
chr8_-_1838315 1.21 ENSDART00000114476
ENSDART00000140077
pi4kab
phosphatidylinositol 4-kinase, catalytic, alpha b
chr25_-_37262220 1.19 ENSDART00000153789
ENSDART00000155182
rfwd3
ring finger and WD repeat domain 3
chr2_+_41526904 1.19 ENSDART00000127520
acvr1l
activin A receptor, type 1 like
chr5_+_40837539 1.18 ENSDART00000188279
si:dkey-3h3.3
si:dkey-3h3.3
chr20_-_48898371 1.18 ENSDART00000170617
xrn2
5'-3' exoribonuclease 2
chr14_-_33945692 1.16 ENSDART00000168546
ENSDART00000189778
zdhhc24
zinc finger, DHHC-type containing 24
chr23_-_35790235 1.12 ENSDART00000142369
ENSDART00000141141
ENSDART00000011004
mfsd5
major facilitator superfamily domain containing 5
chr22_+_14836040 1.10 ENSDART00000180951
gtpbp1l
GTP binding protein 1, like
chr5_-_11809710 1.10 ENSDART00000186998
ENSDART00000181363
ENSDART00000180681
nf2a
neurofibromin 2a (merlin)
chr22_+_4488454 1.09 ENSDART00000170620
ctxn1
cortexin 1
chr17_-_40956035 1.09 ENSDART00000124715
si:dkey-16j16.4
si:dkey-16j16.4
chr23_+_44236281 1.08 ENSDART00000149842
MEPCE
si:ch1073-157b13.1
chr10_+_15255198 1.08 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
vldlr
very low density lipoprotein receptor
chr16_+_47207691 1.08 ENSDART00000062507
ica1
islet cell autoantigen 1
chr20_+_34671386 1.07 ENSDART00000152836
ENSDART00000138226
elp3
elongator acetyltransferase complex subunit 3
chr5_+_29794058 1.06 ENSDART00000045410
thy1
Thy-1 cell surface antigen
chr16_+_29509133 1.06 ENSDART00000112116
ctss2.1
cathepsin S, ortholog2, tandem duplicate 1
chr6_-_41138854 1.06 ENSDART00000128723
ENSDART00000151055
ENSDART00000132484
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr6_+_21001264 1.06 ENSDART00000044519
ENSDART00000151278
cx44.2
connexin 44.2
chr3_-_26244256 1.05 ENSDART00000103741
ppp4ca
protein phosphatase 4, catalytic subunit a
chr16_+_9400661 1.04 ENSDART00000146174
ice1
KIAA0947-like (H. sapiens)
chr10_-_35257458 1.04 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
prr11
proline rich 11
chr11_+_35171406 1.04 ENSDART00000110839
mon1a
MON1 secretory trafficking family member A
chr16_-_42965192 1.02 ENSDART00000113714
mtx1a
metaxin 1a
chr7_+_34592526 1.01 ENSDART00000173959
fhod1
formin homology 2 domain containing 1
chr6_+_40922572 0.99 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr15_-_44601331 0.99 ENSDART00000161514
zgc:165508
zgc:165508
chr19_-_30510259 0.99 ENSDART00000135128
ENSDART00000186169
ENSDART00000182974
ENSDART00000187797
bag6l
BCL2 associated athanogene 6, like
chr23_+_42254960 0.99 ENSDART00000102980
zcchc11
zinc finger, CCHC domain containing 11
chr22_-_17671348 0.98 ENSDART00000137995
tjp3
tight junction protein 3
chr25_-_21031007 0.97 ENSDART00000138985
gnaia
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr1_-_23308225 0.97 ENSDART00000137567
ENSDART00000008201
smim14
small integral membrane protein 14
chr17_+_16046314 0.96 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr3_+_18807006 0.95 ENSDART00000180091
tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr17_+_49500820 0.94 ENSDART00000170306
AREL1
apoptosis resistant E3 ubiquitin protein ligase 1
chr22_-_10440688 0.93 ENSDART00000111962
nol8
nucleolar protein 8
chr5_+_63302660 0.92 ENSDART00000142131
si:ch73-376l24.2
si:ch73-376l24.2
chr21_+_1647990 0.92 ENSDART00000148540
fech
ferrochelatase
chr16_+_25011994 0.91 ENSDART00000157312
znf1035
zinc finger protein 1035
chr25_+_35891342 0.90 ENSDART00000147093
lsm14aa
LSM14A mRNA processing body assembly factor a
chr21_-_32060993 0.90 ENSDART00000131651
si:ch211-160j14.2
si:ch211-160j14.2
chr21_-_19918286 0.89 ENSDART00000180816
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr21_-_31013817 0.89 ENSDART00000065504
ncbp3
nuclear cap binding subunit 3
chr23_-_31913069 0.89 ENSDART00000135526
mtfr2
mitochondrial fission regulator 2
chr17_+_26722904 0.89 ENSDART00000114927
nrde2
NRDE-2, necessary for RNA interference, domain containing
chr12_-_34258384 0.88 ENSDART00000109196
pgs1
phosphatidylglycerophosphate synthase 1
chr15_-_17169935 0.88 ENSDART00000110111
cul5a
cullin 5a
chr5_-_9625459 0.88 ENSDART00000143347
sh2b3
SH2B adaptor protein 3
chr18_+_18000887 0.88 ENSDART00000147797
si:ch211-212o1.2
si:ch211-212o1.2
chr15_-_43978141 0.87 ENSDART00000041249
chordc1a
cysteine and histidine-rich domain (CHORD) containing 1a
chr11_-_45152702 0.87 ENSDART00000168066
afmid
arylformamidase
chr1_-_55068941 0.86 ENSDART00000152143
ENSDART00000152590
peli1a
pellino E3 ubiquitin protein ligase 1a
chr15_-_34930727 0.86 ENSDART00000179723
dhx16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr10_-_32494499 0.86 ENSDART00000129395
uvrag
UV radiation resistance associated gene
chr19_+_2631565 0.86 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr24_+_39518774 0.85 ENSDART00000132939
dcun1d3
defective in cullin neddylation 1 domain containing 3
chr19_+_40069524 0.84 ENSDART00000151365
ENSDART00000140926
zmym4
zinc finger, MYM-type 4
chr6_-_40922971 0.84 ENSDART00000155363
sfi1
SFI1 centrin binding protein
chr3_-_16719244 0.83 ENSDART00000055859
pold1
polymerase (DNA directed), delta 1, catalytic subunit
chr1_+_40613297 0.83 ENSDART00000040798
ENSDART00000168067
ENSDART00000130490
naa15b
N(alpha)-acetyltransferase 15, NatA auxiliary subunit b
chr8_+_8238727 0.83 ENSDART00000144838
plxnb3
plexin B3
chr3_+_22035863 0.82 ENSDART00000177169
cdc27
cell division cycle 27
chr12_+_23912074 0.81 ENSDART00000152864
svila
supervillin a
chr12_+_30367371 0.81 ENSDART00000153364
ccdc186
si:ch211-225b10.4
chr4_+_11723852 0.80 ENSDART00000028820
mkln1
muskelin 1, intracellular mediator containing kelch motifs
chr14_+_16151368 0.79 ENSDART00000160973
polr1a
polymerase (RNA) I polypeptide A
chr10_-_32494304 0.78 ENSDART00000028161
uvrag
UV radiation resistance associated gene
chr4_-_72296520 0.78 ENSDART00000182638
si:cabz01071911.3
si:cabz01071911.3
chr8_+_11425048 0.77 ENSDART00000018739
tjp2b
tight junction protein 2b (zona occludens 2)
chr23_-_32100106 0.77 ENSDART00000044658
letmd1
LETM1 domain containing 1
chr13_+_1015749 0.76 ENSDART00000190982
prokr1b
prokineticin receptor 1b
chr21_-_30994577 0.75 ENSDART00000065503
pgap2
post-GPI attachment to proteins 2
chr5_+_27137473 0.75 ENSDART00000181833
unc5db
unc-5 netrin receptor Db
chr11_-_34219211 0.75 ENSDART00000098472
tmem44
transmembrane protein 44
chr6_-_3982783 0.75 ENSDART00000171944
slc25a12
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr10_+_1849874 0.75 ENSDART00000158897
ENSDART00000149956
apc
adenomatous polyposis coli
chr5_+_6954162 0.74 ENSDART00000086666
stpg2
sperm-tail PG-rich repeat containing 2
chr16_+_28994709 0.73 ENSDART00000088023
gon4l
gon-4-like (C. elegans)
chr14_-_38889311 0.73 ENSDART00000186978
zgc:101583
zgc:101583
chr9_+_54695981 0.73 ENSDART00000183605
rab9a
RAB9A, member RAS oncogene family
chr15_-_34408777 0.73 ENSDART00000139934
agmo
alkylglycerol monooxygenase
chr19_+_42227400 0.72 ENSDART00000131574
ENSDART00000135436
jtb
jumping translocation breakpoint
chr3_+_28860283 0.72 ENSDART00000077235
alg1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr7_+_24573721 0.72 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
si:dkeyp-75h12.7
chr17_-_31611692 0.72 ENSDART00000141480
si:dkey-170l10.1
si:dkey-170l10.1
chr18_+_18000695 0.71 ENSDART00000146898
si:ch211-212o1.2
si:ch211-212o1.2
chr18_-_20458840 0.71 ENSDART00000177125
kif23
kinesin family member 23
chr8_+_25145464 0.71 ENSDART00000136505
gnai3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr17_-_41798856 0.71 ENSDART00000156031
ENSDART00000192801
ENSDART00000180172
ENSDART00000084745
ENSDART00000175577
ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr4_+_65127317 0.71 ENSDART00000166475
znf1126
zinc finger protein 1126
chr12_-_24060358 0.70 ENSDART00000050831
chac2
ChaC, cation transport regulator homolog 2 (E. coli)
chr21_-_3853204 0.68 ENSDART00000188829
st6galnac4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr18_+_44532199 0.68 ENSDART00000135386
st14a
suppression of tumorigenicity 14 (colon carcinoma) a
chr7_+_6915609 0.68 ENSDART00000159213
ccs
copper chaperone for superoxide dismutase
chr20_+_46513651 0.68 ENSDART00000152977
zc3h14
zinc finger CCCH-type containing 14
chr10_-_41302841 0.67 ENSDART00000020297
ENSDART00000160174
ENSDART00000183850
ENSDART00000169493
brf2
BRF2, RNA polymerase III transcription initiation factor
chr9_+_17983463 0.67 ENSDART00000182150
akap11
A kinase (PRKA) anchor protein 11
chr21_+_45502773 0.67 ENSDART00000160059
ENSDART00000165704
si:dkey-223p19.2
si:dkey-223p19.2
chr10_+_518546 0.67 ENSDART00000128275
npffr1l3
neuropeptide FF receptor 1 like 3
chr16_-_17347727 0.67 ENSDART00000144392
zyx
zyxin
chr20_+_36629173 0.66 ENSDART00000161241
ephx1
epoxide hydrolase 1, microsomal (xenobiotic)
chr10_+_35554219 0.65 ENSDART00000077373
zdhhc20a
zinc finger, DHHC-type containing 20a
chr24_-_2450597 0.65 ENSDART00000188080
ENSDART00000093331
rreb1a
ras responsive element binding protein 1a
chr1_+_21937201 0.64 ENSDART00000087729
kdm4c
lysine (K)-specific demethylase 4C
chr7_+_17816006 0.64 ENSDART00000080834
eml3
echinoderm microtubule associated protein like 3
chr4_-_65037243 0.64 ENSDART00000170059
si:ch211-283l16.1
si:ch211-283l16.1
chr5_+_66433287 0.64 ENSDART00000170757
kntc1
kinetochore associated 1
chr12_-_3077395 0.64 ENSDART00000002867
ENSDART00000126315
rfng
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr12_-_18577983 0.63 ENSDART00000193262
zdhhc4
zinc finger, DHHC-type containing 4
chr20_-_9428021 0.63 ENSDART00000025330
rdh14b
retinol dehydrogenase 14b
chr20_-_45060241 0.63 ENSDART00000185227
klhl29
kelch-like family member 29
chr23_-_900795 0.62 ENSDART00000190517
ENSDART00000182849
ENSDART00000111456
ENSDART00000185430
rbm10
RNA binding motif protein 10
chr2_+_41524238 0.62 ENSDART00000122860
ENSDART00000017977
acvr1l
activin A receptor, type 1 like
chr2_-_55298075 0.62 ENSDART00000186404
ENSDART00000149062
rab8a
RAB8A, member RAS oncogene family
chr18_-_43884044 0.62 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr7_-_64589920 0.62 ENSDART00000172619
ENSDART00000184113
CR387919.1

chr15_+_17345609 0.62 ENSDART00000111753
vmp1
vacuole membrane protein 1
chr21_-_25801956 0.62 ENSDART00000101219
mettl27
methyltransferase like 27
chr5_-_26765188 0.61 ENSDART00000029450
rnf181
ring finger protein 181
chr7_-_7764287 0.60 ENSDART00000173021
ENSDART00000113131
intu
inturned planar cell polarity protein
chr17_+_8799451 0.60 ENSDART00000189814
ENSDART00000191577
tonsl
tonsoku-like, DNA repair protein
chr24_-_34680956 0.60 ENSDART00000171009
ctnna1
catenin (cadherin-associated protein), alpha 1
chr7_+_23515966 0.59 ENSDART00000186893
ENSDART00000186189
zgc:109889
zgc:109889
chr12_+_16087077 0.59 ENSDART00000141898
znf281b
zinc finger protein 281b
chr17_-_48944465 0.59 ENSDART00000154110
si:ch1073-80i24.3
si:ch1073-80i24.3
chr11_-_28050559 0.59 ENSDART00000136859
ece1
endothelin converting enzyme 1
chr7_-_17816175 0.59 ENSDART00000091272
ENSDART00000173757
ecsit
ECSIT signalling integrator
chr1_-_47071979 0.59 ENSDART00000160817
itsn1
intersectin 1 (SH3 domain protein)
chr23_+_32028574 0.59 ENSDART00000145501
ENSDART00000143121
ENSDART00000111877
tpx2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr11_+_34523132 0.58 ENSDART00000192257
zmat3
zinc finger, matrin-type 3
chr12_+_30367079 0.58 ENSDART00000190112
ccdc186
si:ch211-225b10.4
chr5_+_60934534 0.58 ENSDART00000065025
rph3al
rabphilin 3A-like (without C2 domains)
chr22_-_6362442 0.57 ENSDART00000149907
ENSDART00000106104
zgc:113298
zgc:113298
chr7_+_17816470 0.57 ENSDART00000173807
eml3
echinoderm microtubule associated protein like 3
chr23_-_31913231 0.57 ENSDART00000146852
ENSDART00000085054
mtfr2
mitochondrial fission regulator 2
chr7_-_12464412 0.56 ENSDART00000178723
adamtsl3
ADAMTS-like 3
chr3_+_16663373 0.55 ENSDART00000100961
zgc:55558
zgc:55558
chr18_-_18875308 0.55 ENSDART00000127182
arl2bp
ADP-ribosylation factor-like 2 binding protein
chr7_+_67749251 0.55 ENSDART00000167562
dhx38
DEAH (Asp-Glu-Ala-His) box polypeptide 38
chr21_+_34088377 0.55 ENSDART00000170070
mtmr1b
myotubularin related protein 1b
chr23_-_14990865 0.55 ENSDART00000147799
ndrg3b
ndrg family member 3b
chr19_-_5805923 0.55 ENSDART00000134340
si:ch211-264f5.8
si:ch211-264f5.8
chr1_-_26444075 0.55 ENSDART00000125690
ints12
integrator complex subunit 12
chr15_+_1534644 0.54 ENSDART00000130413
smc4
structural maintenance of chromosomes 4
chr9_-_5318873 0.54 ENSDART00000129308
ACVR1C
activin A receptor type 1C
chr20_+_22067337 0.54 ENSDART00000152636
clocka
clock circadian regulator a
chr20_+_38458084 0.54 ENSDART00000020153
ENSDART00000135912
coq8a
coenzyme Q8A
chr8_+_7801060 0.54 ENSDART00000161618
tfe3a
transcription factor binding to IGHM enhancer 3a
chr9_-_7287128 0.53 ENSDART00000176281
ENSDART00000065803
mitd1
MIT, microtubule interacting and transport, domain containing 1
chr21_+_4313039 0.52 ENSDART00000141146
HTRA2 (1 of many)
si:dkey-84o3.4
chr11_-_35171768 0.52 ENSDART00000192896
traip
TRAF-interacting protein
chr18_+_6558338 0.52 ENSDART00000110892
b4galnt3b
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr10_-_33297864 0.52 ENSDART00000163360
PRDM15
PR/SET domain 15
chr5_-_25733745 0.51 ENSDART00000051566
zgc:101016
zgc:101016
chr19_+_12406583 0.51 ENSDART00000013865
ENSDART00000151535
seh1l
SEH1-like (S. cerevisiae)
chr12_-_18393408 0.51 ENSDART00000159674
tom1l2
target of myb1 like 2 membrane trafficking protein
chr5_-_8907819 0.50 ENSDART00000188523
adamts12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr15_+_31344472 0.50 ENSDART00000146695
ENSDART00000159182
ENSDART00000060125
or107-1
odorant receptor, family D, subfamily 107, member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxb2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
1.0 3.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.5 1.8 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.4 1.7 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.4 1.5 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.4 1.1 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.3 3.1 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.3 2.8 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.3 0.9 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.2 1.2 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.2 0.7 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.2 0.7 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.2 0.8 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.2 1.5 GO:0034063 stress granule assembly(GO:0034063)
0.2 0.7 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031) Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.2 3.1 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 0.9 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.2 2.6 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.2 0.9 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.2 1.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.2 1.7 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 2.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 0.6 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 1.3 GO:0016119 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.7 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.9 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 1.3 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 1.2 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 0.4 GO:0046104 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.9 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.1 0.6 GO:0000012 single strand break repair(GO:0000012)
0.1 1.6 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.9 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 0.7 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.3 GO:0034214 protein hexamerization(GO:0034214)
0.1 1.0 GO:0030104 water homeostasis(GO:0030104)
0.1 0.4 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.3 GO:0048785 hatching gland development(GO:0048785)
0.1 0.5 GO:0006660 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 1.5 GO:0045471 response to ethanol(GO:0045471)
0.1 0.9 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.5 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 0.6 GO:2001287 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 1.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.7 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 0.4 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.1 0.9 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 0.8 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.8 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 0.7 GO:1990748 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 2.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.3 GO:0017006 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.1 1.3 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 0.8 GO:0009303 rRNA transcription(GO:0009303)
0.1 0.9 GO:0045116 protein neddylation(GO:0045116)
0.1 0.6 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.7 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 0.5 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.1 1.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.5 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 1.0 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.3 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0098581 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.0 1.0 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0030728 ovulation(GO:0030728)
0.0 0.7 GO:0015693 magnesium ion transport(GO:0015693)
0.0 1.2 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.6 GO:0072595 maintenance of protein localization in organelle(GO:0072595)
0.0 0.6 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 1.2 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.5 GO:0048696 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.6 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.6 GO:0016486 peptide hormone processing(GO:0016486)
0.0 1.4 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.8 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.3 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.9 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 1.2 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.5 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.0 0.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.6 GO:0031297 replication fork processing(GO:0031297)
0.0 0.3 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 1.5 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.0 0.7 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.4 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 1.0 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 0.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 1.9 GO:0034504 protein localization to nucleus(GO:0034504)
0.0 0.9 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.9 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.5 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.6 GO:0060173 limb development(GO:0060173)
0.0 2.7 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.6 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 1.0 GO:0007050 cell cycle arrest(GO:0007050)
0.0 1.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 0.1 GO:0003242 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.3 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.9 GO:0051298 centrosome duplication(GO:0051298)
0.0 1.6 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.0 0.1 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.5 GO:0009648 photoperiodism(GO:0009648)
0.0 0.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.3 GO:1903321 negative regulation of protein ubiquitination(GO:0031397) negative regulation of protein modification by small protein conjugation or removal(GO:1903321)
0.0 1.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.6 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.7 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.1 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 1.6 GO:0007283 spermatogenesis(GO:0007283)
0.0 1.4 GO:0099518 vesicle cytoskeletal trafficking(GO:0099518)
0.0 0.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.3 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.3 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.4 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 1.1 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 1.0 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.1 GO:0021576 hindbrain formation(GO:0021576)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.4 1.8 GO:0070724 BMP receptor complex(GO:0070724)
0.3 0.9 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 0.8 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 0.8 GO:0031415 NatA complex(GO:0031415)
0.2 1.4 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.1 0.6 GO:0005880 nuclear microtubule(GO:0005880)
0.1 1.0 GO:0071818 BAT3 complex(GO:0071818)
0.1 4.5 GO:0043186 P granule(GO:0043186)
0.1 1.0 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 0.5 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 1.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 2.0 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.1 0.7 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.7 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 1.1 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.1 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.6 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 3.0 GO:0016592 mediator complex(GO:0016592)
0.1 0.9 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.5 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.1 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 5.7 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.2 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.3 GO:0035517 PR-DUB complex(GO:0035517)
0.0 1.0 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0035060 brahma complex(GO:0035060)
0.0 0.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.7 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.7 GO:0030496 midbody(GO:0030496)
0.0 0.8 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.5 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.4 GO:0008278 cohesin complex(GO:0008278)
0.0 4.3 GO:0005730 nucleolus(GO:0005730)
0.0 1.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.6 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.7 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.8 GO:0009374 biotin binding(GO:0009374)
0.6 3.0 GO:0042809 vitamin D receptor binding(GO:0042809)
0.5 1.4 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.3 1.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.3 0.9 GO:0004061 arylformamidase activity(GO:0004061)
0.3 1.1 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.2 0.7 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.2 3.1 GO:0032190 acrosin binding(GO:0032190)
0.2 1.5 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.2 0.7 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 2.9 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.2 1.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 0.6 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 0.5 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.2 1.8 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.3 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 0.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.4 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.4 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.7 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.5 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.1 1.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.4 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.7 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 0.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.3 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.1 0.7 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.7 GO:0001006 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.1 1.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.7 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.4 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.1 0.8 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 0.3 GO:0051139 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 1.1 GO:0070628 proteasome binding(GO:0070628)
0.1 0.8 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.4 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.1 1.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.3 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.1 0.3 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.1 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 5.3 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.3 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.1 0.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.9 GO:2001069 glycogen binding(GO:2001069)
0.1 1.4 GO:0031267 small GTPase binding(GO:0031267)
0.1 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.9 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 1.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 2.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.3 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.0 0.9 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.8 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 1.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.7 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 3.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.2 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 2.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 1.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.8 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.5 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.7 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 5.0 GO:0042802 identical protein binding(GO:0042802)
0.0 0.3 GO:0045503 dynein light chain binding(GO:0045503)
0.0 1.1 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 1.1 GO:0005178 integrin binding(GO:0005178)
0.0 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.7 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)
0.0 3.0 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 4.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 0.7 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.6 PID REELIN PATHWAY Reelin signaling pathway
0.1 1.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 1.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 0.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.3 PID AURORA B PATHWAY Aurora B signaling
0.0 0.6 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.9 PID EPO PATHWAY EPO signaling pathway
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling
0.0 0.3 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.8 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 1.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.8 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 0.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 0.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.8 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.8 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.4 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.9 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins