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PRJNA195909:zebrafish embryo and larva development

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Results for hoxc11a

Z-value: 1.87

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Transcription factors associated with hoxc11a

Gene Symbol Gene ID Gene Info
hoxc11a
ENSDARG00000070351 homeobox C11a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc11adr11_v1_chr23_+_36074798_360748800.656.0e-02Click!

Activity profile of hoxc11a motif

Sorted Z-values of hoxc11a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_+_10146542 5.33 ENSDART00000048073
zgc:171775
zgc:171775
chr22_-_4644484 5.20 ENSDART00000167748
fbn2b
fibrillin 2b
chr1_+_44439661 4.66 ENSDART00000100309
crybb1l2
crystallin, beta B1, like 2
chr10_-_29903165 4.15 ENSDART00000078800
lim2.1
lens intrinsic membrane protein 2.1
chr17_+_52822831 3.81 ENSDART00000193368
meis2a
Meis homeobox 2a
chr23_+_39606108 3.70 ENSDART00000109464
g0s2
G0/G1 switch 2
chr12_-_25916530 3.68 ENSDART00000186386
sncgb
synuclein, gamma b (breast cancer-specific protein 1)
chr11_+_25257022 3.67 ENSDART00000156052
tp53inp2
tumor protein p53 inducible nuclear protein 2
chr12_+_27117609 3.44 ENSDART00000076154
hoxb8b
homeobox B8b
chr11_+_30244356 3.42 ENSDART00000036050
ENSDART00000150080
rs1a
retinoschisin 1a
chr23_+_36052944 3.40 ENSDART00000103149
hoxc13a
homeobox C13a
chr21_+_5129513 3.37 ENSDART00000102572
thbs4b
thrombospondin 4b
chr23_+_27068225 3.31 ENSDART00000054238
mipa
major intrinsic protein of lens fiber a
chr6_-_60147517 3.26 ENSDART00000083453
slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr6_+_52804267 3.22 ENSDART00000065681
matn4
matrilin 4
chr25_+_29161609 3.12 ENSDART00000180752
pkmb
pyruvate kinase M1/2b
chr25_+_20089986 3.11 ENSDART00000143441
ENSDART00000184073
tnni4b.2
troponin I4b, tandem duplicate 2
chr22_-_14115292 2.98 ENSDART00000105717
ENSDART00000165670
aox5
aldehyde oxidase 5
chr6_+_35362225 2.90 ENSDART00000133783
ENSDART00000102483
rgs4
regulator of G protein signaling 4
chr12_+_6041575 2.89 ENSDART00000091868
g6pca.2
glucose-6-phosphatase a, catalytic subunit, tandem duplicate 2
chr1_+_46194333 2.78 ENSDART00000010894
sox1b
SRY (sex determining region Y)-box 1b
chr13_+_22675802 2.78 ENSDART00000145538
ENSDART00000143312
zgc:193505
zgc:193505
chr19_-_28789404 2.69 ENSDART00000191453
ENSDART00000026992
sox4a
SRY (sex determining region Y)-box 4a
chr2_+_2223837 2.62 ENSDART00000101038
ENSDART00000129354
tmie
transmembrane inner ear
chr5_-_42272517 2.59 ENSDART00000137692
ENSDART00000164363
si:ch211-207c6.2
si:ch211-207c6.2
chr6_+_12853655 2.59 ENSDART00000156341
fam117ba
family with sequence similarity 117, member Ba
chr17_+_52822422 2.58 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr6_-_26559921 2.53 ENSDART00000104532
sox14
SRY (sex determining region Y)-box 14
chr8_+_39619087 2.48 ENSDART00000134822
msi1
musashi RNA-binding protein 1
chr19_+_19747430 2.43 ENSDART00000166129
hoxa9a
homeobox A9a
chr9_-_1949915 2.36 ENSDART00000190712
hoxd3a
homeobox D3a
chr9_-_42696408 2.34 ENSDART00000144744
col5a2a
collagen, type V, alpha 2a
chr16_+_32995882 2.31 ENSDART00000170157
prss35
protease, serine, 35
chr20_+_26880668 2.31 ENSDART00000077769
serpinb1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr12_-_20373058 2.26 ENSDART00000066382
aqp8a.1
aquaporin 8a, tandem duplicate 1
chr6_+_40629066 2.25 ENSDART00000103757
slc6a11a
solute carrier family 6 (neurotransmitter transporter), member 11a
chr3_+_23731109 2.16 ENSDART00000131410
hoxb3a
homeobox B3a
chr5_-_40510397 2.14 ENSDART00000146237
ENSDART00000051065
fsta
follistatin a
chr17_+_52823015 2.14 ENSDART00000160507
ENSDART00000186979
meis2a
Meis homeobox 2a
chr20_+_52546186 2.11 ENSDART00000110777
ENSDART00000153377
ENSDART00000153013
ENSDART00000042704
eef1db
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr10_+_36650222 2.06 ENSDART00000126963
ucp3
uncoupling protein 3
chr17_-_12389259 2.00 ENSDART00000185724
snap25b
synaptosomal-associated protein, 25b
chr7_+_39386982 1.99 ENSDART00000146702
tnni2b.2
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr2_+_20406399 1.96 ENSDART00000006817
ENSDART00000137848
palmda
palmdelphin a
chr24_-_6158933 1.95 ENSDART00000021609
gad2
glutamate decarboxylase 2
chr21_+_19070921 1.95 ENSDART00000029874
nkx6.1
NK6 homeobox 1
chr4_+_5741733 1.95 ENSDART00000110243
pou3f2a
POU class 3 homeobox 2a
chr11_+_6116503 1.93 ENSDART00000176170
nr2f6b
nuclear receptor subfamily 2, group F, member 6b
chr23_+_25354856 1.91 ENSDART00000109023
ENSDART00000147440
fmnl3
formin-like 3
chr3_+_25154078 1.86 ENSDART00000156973
si:ch211-256m1.8
si:ch211-256m1.8
chr24_+_5237753 1.80 ENSDART00000106488
ENSDART00000005901
plod2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr11_-_18253111 1.77 ENSDART00000125984
mustn1b
musculoskeletal, embryonic nuclear protein 1b
chr11_+_2198831 1.76 ENSDART00000160515
hoxc6b
homeobox C6b
chr20_+_6659770 1.75 ENSDART00000192135
tns3.2
tensin 3, tandem duplicate 2
chr19_+_19762183 1.74 ENSDART00000163611
ENSDART00000187604
hoxa3a
homeobox A3a
chr21_+_25236297 1.72 ENSDART00000112783
tmem45b
transmembrane protein 45B
chr23_-_12014931 1.70 ENSDART00000134652
si:dkey-178k16.1
si:dkey-178k16.1
chr3_+_16265924 1.70 ENSDART00000122519
st8sia6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr9_-_48370645 1.66 ENSDART00000140185
col28a2a
collagen, type XXVIII, alpha 2a
chr24_-_8732519 1.64 ENSDART00000082351
tfap2a
transcription factor AP-2 alpha
chr7_-_30367650 1.63 ENSDART00000075519
aldh1a2
aldehyde dehydrogenase 1 family, member A2
chr14_+_49135264 1.62 ENSDART00000084119
si:ch1073-44g3.1
si:ch1073-44g3.1
chr6_+_58915889 1.59 ENSDART00000083628
ddit3
DNA-damage-inducible transcript 3
chr7_+_25059845 1.58 ENSDART00000077215
ppp2r5b
protein phosphatase 2, regulatory subunit B', beta
chr9_+_17306162 1.53 ENSDART00000075926
scel
sciellin
chr1_-_35924495 1.48 ENSDART00000184424
smad1
SMAD family member 1
chr18_-_15373620 1.46 ENSDART00000031752
rfx4
regulatory factor X, 4
chr18_+_48446704 1.43 ENSDART00000134817
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr7_+_36041509 1.42 ENSDART00000162850
irx3a
iroquois homeobox 3a
chr8_-_34052019 1.40 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pbx3b
pre-B-cell leukemia homeobox 3b
chr15_-_34567370 1.39 ENSDART00000099793
sostdc1a
sclerostin domain containing 1a
chr10_+_26612321 1.36 ENSDART00000134322
fhl1b
four and a half LIM domains 1b
chr8_+_19668654 1.34 ENSDART00000091436
foxe3
forkhead box E3
chr20_+_43925266 1.34 ENSDART00000037379
clic5b
chloride intracellular channel 5b
chr16_-_26676685 1.34 ENSDART00000103431
esrp1
epithelial splicing regulatory protein 1
chr20_-_25709247 1.33 ENSDART00000146711
si:dkeyp-117h8.2
si:dkeyp-117h8.2
chr9_+_44431174 1.30 ENSDART00000149726
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr23_-_7799184 1.28 ENSDART00000190946
ENSDART00000165427
myt1b
myelin transcription factor 1b
chr9_+_34425736 1.27 ENSDART00000135147
si:ch211-218d20.15
si:ch211-218d20.15
chr4_-_5652030 1.27 ENSDART00000010903
rsph9
radial spoke head 9 homolog
chr1_+_36437585 1.25 ENSDART00000189182
pou4f2
POU class 4 homeobox 2
chr24_+_9412450 1.25 ENSDART00000132724
si:ch211-285f17.1
si:ch211-285f17.1
chr11_+_42556395 1.23 ENSDART00000039206
rps23
ribosomal protein S23
chr21_-_25756119 1.23 ENSDART00000002341
cldnc
claudin c
chr8_+_14381272 1.19 ENSDART00000057642
acbd6
acyl-CoA binding domain containing 6
chr7_-_26844064 1.18 ENSDART00000162241
si:ch211-107p11.3
si:ch211-107p11.3
chr18_-_15559817 1.18 ENSDART00000061681
si:ch211-245j22.3
si:ch211-245j22.3
chr11_-_21586157 1.18 ENSDART00000190095
srgap2
SLIT-ROBO Rho GTPase activating protein 2
chr17_-_43666166 1.16 ENSDART00000077990
egr2a
early growth response 2a
chr11_+_21053488 1.15 ENSDART00000189860
zgc:113307
zgc:113307
chr19_-_10243148 1.14 ENSDART00000148073
shisa7b
shisa family member 7
chr17_-_17764801 1.11 ENSDART00000155261
slirp
SRA stem-loop interacting RNA binding protein
chr7_+_30875273 1.11 ENSDART00000173693
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr1_+_5402476 1.09 ENSDART00000040204
tuba8l2
tubulin, alpha 8 like 2
chr14_-_12837432 1.06 ENSDART00000178444
gria3b
glutamate receptor, ionotropic, AMPA 3b
chr5_+_11290851 1.06 ENSDART00000180408
CABZ01077124.1

chr1_-_22512063 1.05 ENSDART00000031546
ENSDART00000190987
chrna6
cholinergic receptor, nicotinic, alpha 6
chr25_-_26758253 1.05 ENSDART00000123004
si:dkeyp-73b11.8
si:dkeyp-73b11.8
chr14_-_12837052 1.04 ENSDART00000165004
ENSDART00000043180
gria3b
glutamate receptor, ionotropic, AMPA 3b
chr5_+_24245682 1.04 ENSDART00000049003
atp6v1aa
ATPase H+ transporting V1 subunit Aa
chr1_+_27868294 1.02 ENSDART00000165332
dnajb14
DnaJ (Hsp40) homolog, subfamily B, member 14
chr16_+_10918252 1.02 ENSDART00000172949
pou2f2a
POU class 2 homeobox 2a
chr24_+_39105051 0.99 ENSDART00000115297
mss51
MSS51 mitochondrial translational activator
chr1_-_39976492 0.97 ENSDART00000181680
stox2a
storkhead box 2a
chr9_-_11550711 0.96 ENSDART00000093343
fev
FEV (ETS oncogene family)
chr22_+_5176255 0.95 ENSDART00000092647
cers1
ceramide synthase 1
chr16_+_23087326 0.95 ENSDART00000167518
ENSDART00000161087
efna3b
ephrin-A3b
chr7_+_61480296 0.95 ENSDART00000083255
adam19a
ADAM metallopeptidase domain 19a
chr15_-_19772372 0.94 ENSDART00000152729
picalmb
phosphatidylinositol binding clathrin assembly protein b
chr9_+_44430974 0.93 ENSDART00000056846
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr3_+_24134418 0.93 ENSDART00000156204
si:ch211-246i5.5
si:ch211-246i5.5
chr11_-_6265574 0.93 ENSDART00000181974
ENSDART00000104405
ccl25b
chemokine (C-C motif) ligand 25b
chr9_-_16853462 0.92 ENSDART00000160273
CT573248.2

chr17_-_30975707 0.92 ENSDART00000138346
evla
Enah/Vasp-like a
chr19_+_19761966 0.90 ENSDART00000163697
hoxa3a
homeobox A3a
chr9_+_917060 0.89 ENSDART00000082390
tmem37
transmembrane protein 37
chr23_+_18722715 0.87 ENSDART00000137438
myh7bb
myosin, heavy chain 7B, cardiac muscle, beta b
chr20_+_30490682 0.86 ENSDART00000184871
myt1la
myelin transcription factor 1-like, a
chr9_-_41784799 0.86 ENSDART00000144573
ENSDART00000112542
ENSDART00000190486
obsl1b
obscurin-like 1b
chr10_-_10864331 0.86 ENSDART00000122657
nrarpa
NOTCH regulated ankyrin repeat protein a
chr6_-_40697585 0.86 ENSDART00000113196
si:ch211-157b11.14
si:ch211-157b11.14
chr2_+_52847049 0.86 ENSDART00000121980
creb3l3b
cAMP responsive element binding protein 3-like 3b
chr8_-_52413032 0.84 ENSDART00000183039
CABZ01070469.1

chr2_-_27329667 0.84 ENSDART00000187490
tmx3a
thioredoxin related transmembrane protein 3a
chr17_-_19019635 0.84 ENSDART00000126666
flrt2
fibronectin leucine rich transmembrane protein 2
chr6_-_50203682 0.82 ENSDART00000083999
ENSDART00000143050
raly
RALY heterogeneous nuclear ribonucleoprotein
chr25_+_37126921 0.82 ENSDART00000124331
si:ch1073-174d20.1
si:ch1073-174d20.1
chr8_-_25327809 0.79 ENSDART00000137242
eps8l3b
EPS8-like 3b
chr11_-_15090564 0.79 ENSDART00000162079
slc1a8a
solute carrier family 1 (glutamate transporter), member 8a
chr23_+_28648864 0.79 ENSDART00000189096
l1cama
L1 cell adhesion molecule, paralog a
chr11_-_6188413 0.79 ENSDART00000109972
ccl44
chemokine (C-C motif) ligand 44
chr10_+_2587234 0.77 ENSDART00000126937
wu:fb59d01
wu:fb59d01
chr20_-_47731768 0.76 ENSDART00000031167
tfap2d
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr23_+_23918421 0.76 ENSDART00000046951
ptpn11b
protein tyrosine phosphatase, non-receptor type 11, b
chr17_-_18888959 0.75 ENSDART00000080029
ak7b
adenylate kinase 7b
chr3_+_62161184 0.75 ENSDART00000090370
ENSDART00000192665
noxo1a
NADPH oxidase organizer 1a
chr3_-_19200571 0.75 ENSDART00000131503
ENSDART00000012335
rfx1a
regulatory factor X, 1a (influences HLA class II expression)
chr16_+_44768361 0.74 ENSDART00000036302
upk1a
uroplakin 1a
chr5_+_37785152 0.73 ENSDART00000053511
ENSDART00000189812
myo1ca
myosin Ic, paralog a
chr2_+_5927255 0.73 ENSDART00000152866
si:ch211-168b3.2
si:ch211-168b3.2
chr20_+_20726231 0.73 ENSDART00000147112
zgc:193541
zgc:193541
chr9_+_41080029 0.70 ENSDART00000141179
ENSDART00000019289
zgc:136439
zgc:136439
chr20_-_27733683 0.70 ENSDART00000103317
ENSDART00000138139
zgc:153157
zgc:153157
chr11_-_12998400 0.68 ENSDART00000018614
chrna4b
cholinergic receptor, nicotinic, alpha 4b
chr10_+_16069987 0.68 ENSDART00000043936
megf10
multiple EGF-like-domains 10
chr15_-_17869115 0.67 ENSDART00000112838
atf5b
activating transcription factor 5b
chr20_-_4883673 0.67 ENSDART00000145540
ENSDART00000053877
zdhhc14
zinc finger, DHHC-type containing 14
chr2_-_30659222 0.65 ENSDART00000145405
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr24_+_5840258 0.64 ENSDART00000087034
trpc1
transient receptor potential cation channel, subfamily C, member 1
chr24_+_25259154 0.64 ENSDART00000171125
gabrr3b
gamma-aminobutyric acid (GABA) A receptor, rho 3b
chr11_+_14284866 0.63 ENSDART00000163729
si:ch211-262i1.3
si:ch211-262i1.3
chr6_+_23931236 0.62 ENSDART00000166079
gadd45ab
growth arrest and DNA-damage-inducible, alpha, b
chr10_-_34772211 0.62 ENSDART00000145450
ENSDART00000134307
dclk1a
doublecortin-like kinase 1a
chr10_-_34889053 0.61 ENSDART00000136966
ccdc169
coiled-coil domain containing 169
chr5_-_63218919 0.60 ENSDART00000149979
tecta
tectorin alpha
chr3_+_24190207 0.59 ENSDART00000034762
prr15la
proline rich 15-like a
chr13_+_29519115 0.57 ENSDART00000086711
chst3a
carbohydrate (chondroitin 6) sulfotransferase 3a
chr13_+_36585399 0.56 ENSDART00000030211
gmfb
glia maturation factor, beta
chr4_-_56898328 0.56 ENSDART00000169189
si:dkey-269o24.6
si:dkey-269o24.6
chr11_-_29737088 0.55 ENSDART00000159828
si:ch211-218g23.6
si:ch211-218g23.6
chr4_-_71177920 0.55 ENSDART00000158287
si:dkey-193i10.1
si:dkey-193i10.1
chr1_+_27153859 0.55 ENSDART00000180184
bnc2
basonuclin 2
chr1_+_961607 0.53 ENSDART00000184660
n6amt1
N-6 adenine-specific DNA methyltransferase 1
chr9_+_54290896 0.53 ENSDART00000149175
pou4f3
POU class 4 homeobox 3
chr2_+_45068366 0.52 ENSDART00000142175
si:dkey-76d14.2
si:dkey-76d14.2
chr16_+_13883872 0.50 ENSDART00000101304
ENSDART00000136005
atg12
ATG12 autophagy related 12 homolog (S. cerevisiae)
chr7_-_26457208 0.48 ENSDART00000173519
zgc:172079
zgc:172079
chr7_-_29341233 0.48 ENSDART00000140938
ENSDART00000147251
trpm1a
transient receptor potential cation channel, subfamily M, member 1a
chr2_-_27329214 0.48 ENSDART00000145835
tmx3a
thioredoxin related transmembrane protein 3a
chr6_-_6448519 0.47 ENSDART00000180157
ENSDART00000191112
si:ch211-194e18.2
si:ch211-194e18.2
chr11_+_41243325 0.47 ENSDART00000170657
pax7a
paired box 7a
chr10_-_25591194 0.46 ENSDART00000131640
tiam1a
T cell lymphoma invasion and metastasis 1a
chr23_-_27571667 0.45 ENSDART00000008174
pfkma
phosphofructokinase, muscle a
chr2_-_17235891 0.44 ENSDART00000144251
artnb
artemin b
chr8_+_30709685 0.42 ENSDART00000133989
upb1
ureidopropionase, beta
chr1_-_19215336 0.41 ENSDART00000162949
ENSDART00000170680
ptprdb
protein tyrosine phosphatase, receptor type, D, b
chr7_+_18075504 0.39 ENSDART00000173689
si:ch73-40a2.1
si:ch73-40a2.1
chr23_+_7379728 0.38 ENSDART00000012194
gata5
GATA binding protein 5
chr11_-_15090118 0.38 ENSDART00000171118
slc1a8a
solute carrier family 1 (glutamate transporter), member 8a
chr2_-_9607879 0.37 ENSDART00000056899
txndc12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr19_+_1003332 0.37 ENSDART00000081779
zdhhc3b
zinc finger, DHHC-type containing 3b
chr22_+_31821815 0.37 ENSDART00000159825
dock3
dedicator of cytokinesis 3
chr4_+_43522945 0.36 ENSDART00000183921
ENSDART00000181832
si:dkeyp-53e4.4
si:dkeyp-53e4.4
chr8_-_19280856 0.35 ENSDART00000100473
zgc:77486
zgc:77486
chr12_-_46959990 0.35 ENSDART00000084557
lhpp
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr2_+_19785540 0.34 ENSDART00000149789
ptbp2b
polypyrimidine tract binding protein 2b
chr20_+_6543674 0.34 ENSDART00000134204
tns3.1
tensin 3, tandem duplicate 1
chr20_+_27428505 0.34 ENSDART00000002641
kif26aa
kinesin family member 26Aa
chr15_+_14856307 0.34 ENSDART00000167213
diabloa
diablo, IAP-binding mitochondrial protein a
chr24_+_4434117 0.32 ENSDART00000184349
GJD4
gap junction protein delta 4
chr1_+_44826593 0.31 ENSDART00000162200
STX3
zgc:165520
chr5_+_31946973 0.31 ENSDART00000189876
ENSDART00000163366
ungb
uracil DNA glycosylase b
chr19_+_42469058 0.30 ENSDART00000076915
si:dkey-166k12.1
si:dkey-166k12.1
chr18_-_14941840 0.30 ENSDART00000091729
mlc1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr17_-_26610814 0.29 ENSDART00000133402
ENSDART00000016608
mrpl57
mitochondrial ribosomal protein L57
chr17_-_47090440 0.29 ENSDART00000163542
CABZ01056321.1

chr19_+_7810028 0.29 ENSDART00000081592
ENSDART00000140719
aqp10b
aquaporin 10b
chr1_-_9228007 0.28 ENSDART00000147277
ENSDART00000135219
gng13a
guanine nucleotide binding protein (G protein), gamma 13a
chr21_-_20328375 0.28 ENSDART00000079593
slc26a1
solute carrier family 26 (anion exchanger), member 1
chr17_+_31221761 0.28 ENSDART00000155580
ccdc32
coiled-coil domain containing 32

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc11a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0003250 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.7 2.0 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.6 3.4 GO:0035989 tendon development(GO:0035989)
0.5 1.8 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.4 1.3 GO:1902746 negative regulation of epithelial cell differentiation(GO:0030857) regulation of lens fiber cell differentiation(GO:1902746)
0.4 1.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.4 3.3 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.4 1.6 GO:0061113 pancreas morphogenesis(GO:0061113)
0.4 3.6 GO:0006833 water transport(GO:0006833)
0.4 1.6 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.4 2.6 GO:0060017 parathyroid gland development(GO:0060017)
0.4 1.8 GO:0035988 chondrocyte proliferation(GO:0035988)
0.3 1.3 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.3 1.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.3 0.9 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.2 2.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.2 1.2 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.2 1.1 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.2 1.7 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.2 2.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 1.5 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.2 2.0 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 3.7 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 2.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 2.6 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 1.9 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.8 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 3.7 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.4 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.1 1.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 5.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.6 GO:0035889 otolith tethering(GO:0035889)
0.1 0.5 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.1 1.6 GO:0035778 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014)
0.1 0.4 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.4 GO:0019482 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.1 1.6 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 0.4 GO:0061687 DNA damage response, detection of DNA damage(GO:0042769) detoxification of inorganic compound(GO:0061687)
0.1 0.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 0.9 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 2.6 GO:0046847 filopodium assembly(GO:0046847)
0.1 0.3 GO:0019532 oxalate transport(GO:0019532)
0.1 2.5 GO:0021761 limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.1 0.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 2.7 GO:0061386 closure of optic fissure(GO:0061386)
0.1 6.6 GO:0009880 embryonic pattern specification(GO:0009880)
0.1 0.2 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.1 0.3 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.1 0.7 GO:0035094 response to nicotine(GO:0035094)
0.1 0.2 GO:0042148 strand invasion(GO:0042148)
0.1 3.6 GO:0006096 glycolytic process(GO:0006096)
0.1 0.5 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.1 1.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.9 GO:0014823 response to activity(GO:0014823)
0.0 3.6 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 1.0 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 0.6 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0003403 optic vesicle formation(GO:0003403)
0.0 4.7 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 3.4 GO:0031101 fin regeneration(GO:0031101)
0.0 1.0 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 2.1 GO:0006414 translational elongation(GO:0006414)
0.0 0.9 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 2.2 GO:1990542 mitochondrial transmembrane transport(GO:1990542)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.7 GO:0006165 nucleoside diphosphate phosphorylation(GO:0006165)
0.0 1.0 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.7 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.3 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.7 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.3 GO:0050909 sensory perception of taste(GO:0050909)
0.0 1.4 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.6 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.6 GO:0051289 protein homotetramerization(GO:0051289)
0.0 1.9 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.5 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 5.7 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 1.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.7 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.8 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.9 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 2.0 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.7 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 1.5 GO:0008544 epidermis development(GO:0008544)
0.0 0.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.5 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.9 GO:0010842 retina layer formation(GO:0010842)
0.0 4.0 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 1.0 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0005588 collagen type V trimer(GO:0005588)
0.4 1.3 GO:0001534 radial spoke(GO:0001534)
0.3 2.0 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.3 2.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 3.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 0.7 GO:0060171 stereocilium membrane(GO:0060171)
0.1 5.1 GO:0005861 troponin complex(GO:0005861)
0.1 3.7 GO:0016605 PML body(GO:0016605)
0.1 3.7 GO:0044306 axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
0.1 0.9 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 1.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.8 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 1.0 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.2 GO:0044327 dendritic spine head(GO:0044327) phagocytic vesicle(GO:0045335)
0.0 1.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 3.5 GO:0005581 collagen trimer(GO:0005581)
0.0 2.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 5.2 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.1 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 1.7 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 4.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0044545 NSL complex(GO:0044545)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:1903136 cuprous ion binding(GO:1903136)
1.0 3.0 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.7 2.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.6 5.6 GO:0015250 water channel activity(GO:0015250)
0.6 1.8 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.5 3.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.5 2.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.4 1.9 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.3 3.3 GO:0015295 solute:proton symporter activity(GO:0015295)
0.2 1.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 1.3 GO:0016972 thiol oxidase activity(GO:0016972)
0.2 1.4 GO:0036122 BMP binding(GO:0036122)
0.2 0.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.7 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 5.3 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.6 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.1 2.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.6 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 8.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.1 GO:0048185 activin binding(GO:0048185)
0.1 1.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.3 GO:0004427 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.1 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.6 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 13.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 0.2 GO:0000150 recombinase activity(GO:0000150)
0.1 9.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.5 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.6 GO:0005522 profilin binding(GO:0005522)
0.1 1.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 2.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 2.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.2 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.9 GO:0035497 cAMP response element binding(GO:0035497)
0.0 2.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 1.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 4.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 1.4 GO:0044325 ion channel binding(GO:0044325)
0.0 1.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.3 GO:0005254 chloride channel activity(GO:0005254)
0.0 3.4 GO:0008083 growth factor activity(GO:0008083)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 28.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0005372 water transmembrane transporter activity(GO:0005372)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 3.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 1.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.6 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 1.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 2.9 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 1.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 3.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 1.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 2.1 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 1.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion