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PRJNA195909:zebrafish embryo and larva development

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Results for hoxc13a

Z-value: 0.88

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Transcription factors associated with hoxc13a

Gene Symbol Gene ID Gene Info
hoxc13a
ENSDARG00000070353 homeobox C13a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc13adr11_v1_chr23_+_36052944_360529440.511.6e-01Click!

Activity profile of hoxc13a motif

Sorted Z-values of hoxc13a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_24215046 2.71 ENSDART00000079215
stc2a
stanniocalcin 2a
chr25_+_31277415 2.45 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr2_+_56891858 1.90 ENSDART00000159912
zgc:85843
zgc:85843
chr25_+_31276842 1.79 ENSDART00000187238
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr7_-_23873173 1.61 ENSDART00000101408
zgc:162171
zgc:162171
chr21_+_11503212 1.61 ENSDART00000146701
si:dkey-184p9.7
si:dkey-184p9.7
chr15_-_23647078 1.57 ENSDART00000059366
ckmb
creatine kinase, muscle b
chr2_+_48288461 1.48 ENSDART00000141495
hes6
hes family bHLH transcription factor 6
chr23_+_36115541 1.34 ENSDART00000130090
hoxc6a
homeobox C6a
chr8_-_28449782 1.25 ENSDART00000062702
cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr14_-_5546497 1.25 ENSDART00000054877
fgf24
fibroblast growth factor 24
chr20_+_23238833 1.20 ENSDART00000074167
ociad2
OCIA domain containing 2
chr23_-_21471022 1.13 ENSDART00000104206
her4.2
hairy-related 4, tandem duplicate 2
chr24_-_26282672 1.09 ENSDART00000176663
and1
actinodin1
chr20_-_27086143 1.01 ENSDART00000008590
itpk1a
inositol-tetrakisphosphate 1-kinase a
chr3_+_23691847 0.94 ENSDART00000078453
hoxb7a
homeobox B7a
chr5_-_34993242 0.93 ENSDART00000134516
ENSDART00000051295
btf3
basic transcription factor 3
chr12_+_48204891 0.90 ENSDART00000190534
ENSDART00000164427
ndr2
nodal-related 2
chr7_+_24114694 0.88 ENSDART00000127177
mrpl52
mitochondrial ribosomal protein L52
chr9_-_1959917 0.88 ENSDART00000082359
hoxd3a
homeobox D3a
chr19_+_4916233 0.86 ENSDART00000159512
ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr24_-_6158933 0.83 ENSDART00000021609
gad2
glutamate decarboxylase 2
chr4_+_37406676 0.79 ENSDART00000130981
si:ch73-134f24.1
si:ch73-134f24.1
chr4_+_306036 0.78 ENSDART00000103659
msgn1
mesogenin 1
chr21_-_25756119 0.78 ENSDART00000002341
cldnc
claudin c
chr4_-_16545085 0.75 ENSDART00000033188
btg1
B-cell translocation gene 1, anti-proliferative
chr5_-_31875645 0.73 ENSDART00000098160
tmem119b
transmembrane protein 119b
chr25_-_15214161 0.71 ENSDART00000031499
wt1a
wilms tumor 1a
chr16_-_36099492 0.71 ENSDART00000180905
CU499336.2

chr20_-_26420939 0.68 ENSDART00000110883
akap12b
A kinase (PRKA) anchor protein 12b
chr20_-_26421112 0.65 ENSDART00000183767
ENSDART00000182330
akap12b
A kinase (PRKA) anchor protein 12b
chr3_-_23474416 0.65 ENSDART00000161672
si:dkey-225f5.5
si:dkey-225f5.5
chr6_+_49412754 0.65 ENSDART00000027398
kcna2a
potassium voltage-gated channel, shaker-related subfamily, member 2a
chr16_-_4203022 0.64 ENSDART00000018686
rrp15
ribosomal RNA processing 15 homolog
chr3_-_7656059 0.63 ENSDART00000170917
junbb
JunB proto-oncogene, AP-1 transcription factor subunit b
chr9_-_1965727 0.62 ENSDART00000082354
hoxd9a
homeobox D9a
chr23_+_41912151 0.60 ENSDART00000191115
podn
podocan
chr25_-_1720736 0.59 ENSDART00000097256
SLC6A13
solute carrier family 6 member 13
chr4_+_73672430 0.58 ENSDART00000174310
ENSDART00000150505
si:dkey-262g12.7
si:dkey-262g12.7
chr13_-_24447332 0.56 ENSDART00000043004
slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr3_+_59851537 0.55 ENSDART00000180997
CU693479.1

chr15_-_24883956 0.54 ENSDART00000113199
aipl1
aryl hydrocarbon receptor interacting protein-like 1
chr11_-_33857911 0.53 ENSDART00000165370
nxph2b
neurexophilin 2b
chr5_-_19014589 0.53 ENSDART00000002624
ranbp1
RAN binding protein 1
chr4_+_5132951 0.52 ENSDART00000103279
ccnd2b
cyclin D2, b
chr10_+_37927100 0.52 ENSDART00000172548
bhlha9
basic helix-loop-helix family, member a9
chr16_+_22618620 0.52 ENSDART00000185728
ENSDART00000041625
chrnb2b
cholinergic receptor, nicotinic, beta 2b
chr19_+_19756425 0.52 ENSDART00000167606
hoxa3a
homeobox A3a
chr16_-_23800484 0.52 ENSDART00000139964
rps27.2
ribosomal protein S27, isoform 2
chr18_+_48428713 0.50 ENSDART00000076861
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr6_-_40098641 0.50 ENSDART00000017402
ip6k2b
inositol hexakisphosphate kinase 2b
chr17_+_42274825 0.49 ENSDART00000020156
pax1a
paired box 1a
chr1_-_40994259 0.49 ENSDART00000101562
adra2c
adrenoceptor alpha 2C
chr9_+_22003942 0.48 ENSDART00000091013
si:dkey-57a22.15
si:dkey-57a22.15
chr2_-_56095275 0.47 ENSDART00000154701
si:ch211-178n15.1
si:ch211-178n15.1
chr25_-_3230187 0.47 ENSDART00000160545
cib1
calcium and integrin binding 1 (calmyrin)
chr6_+_13779857 0.46 ENSDART00000154793
tmem198b
transmembrane protein 198b
chr25_+_28776562 0.46 ENSDART00000109702
slc41a2a
solute carrier family 41 (magnesium transporter), member 2a
chr13_+_22295905 0.45 ENSDART00000180133
ENSDART00000181125
usp54a
ubiquitin specific peptidase 54a
chr15_+_16387088 0.43 ENSDART00000101789
flot2b
flotillin 2b
chr15_-_25518084 0.43 ENSDART00000158594
hif1al
hypoxia-inducible factor 1, alpha subunit, like
chr3_+_29640996 0.42 ENSDART00000011052
eif3d
eukaryotic translation initiation factor 3, subunit D
chr22_+_18477934 0.41 ENSDART00000132684
cilp2
cartilage intermediate layer protein 2
chr1_+_961607 0.41 ENSDART00000184660
n6amt1
N-6 adenine-specific DNA methyltransferase 1
chr18_-_2433011 0.40 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr4_+_41835660 0.40 ENSDART00000171428
si:ch211-268b14.2
si:ch211-268b14.2
chr2_-_56655769 0.39 ENSDART00000113589
gpx4b
glutathione peroxidase 4b
chr24_+_1294176 0.39 ENSDART00000106637
si:ch73-134f24.1
si:ch73-134f24.1
chr12_-_10038870 0.39 ENSDART00000152250
ngfrb
nerve growth factor receptor b
chr6_-_54816567 0.38 ENSDART00000150079
tnni1b
troponin I type 1b (skeletal, slow)
chr25_+_35051656 0.38 ENSDART00000133379
hist2h3c
histone cluster 2, H3c
chr16_-_26296477 0.37 ENSDART00000157553
erfl1
Ets2 repressor factor like 1
chr25_-_31739309 0.37 ENSDART00000098896
acot19
acyl-CoA thioesterase 19
chr19_-_31007417 0.37 ENSDART00000048144
rbbp4
retinoblastoma binding protein 4
chr23_+_28582865 0.37 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr14_-_3032016 0.37 ENSDART00000183461
ENSDART00000183035
ndst1a
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1a
chr11_-_16093018 0.36 ENSDART00000139309
ENSDART00000139819
SPATA1
si:dkey-205k8.5
chr9_-_23990416 0.35 ENSDART00000113176
col6a3
collagen, type VI, alpha 3
chr9_-_33785093 0.34 ENSDART00000140779
ENSDART00000059837
fundc1
FUN14 domain containing 1
chr2_+_24374305 0.33 ENSDART00000022379
nr2f6a
nuclear receptor subfamily 2, group F, member 6a
chr17_+_31221761 0.32 ENSDART00000155580
ccdc32
coiled-coil domain containing 32
chr14_-_3031810 0.32 ENSDART00000090213
ndst1a
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1a
chr2_-_20323901 0.32 ENSDART00000125531
plppr5a
phospholipid phosphatase related 5a
chr2_+_38147761 0.32 ENSDART00000135307
sall2
spalt-like transcription factor 2
chr13_-_10261383 0.31 ENSDART00000080808
six3a
SIX homeobox 3a
chr13_-_1349922 0.31 ENSDART00000140970
si:ch73-52p7.1
si:ch73-52p7.1
chr5_+_32932357 0.31 ENSDART00000192397
lmo4a
LIM domain only 4a
chr17_-_3291369 0.30 ENSDART00000181840
CABZ01007222.1

chr15_+_27387555 0.30 ENSDART00000018603
tbx4
T-box 4
chr6_+_24661736 0.30 ENSDART00000169283
znf644b
zinc finger protein 644b
chr13_-_2440622 0.30 ENSDART00000102767
ENSDART00000172616
fbxo9
F-box protein 9
chr4_+_42419522 0.29 ENSDART00000135737
si:dkey-16p6.1
si:dkey-16p6.1
chr19_-_28367413 0.29 ENSDART00000079092
si:dkey-261i16.5
si:dkey-261i16.5
chr21_-_21537452 0.27 ENSDART00000142549
or133-7
odorant receptor, family H, subfamily 133, member 7
chr12_-_34435604 0.27 ENSDART00000115088
birc5a
baculoviral IAP repeat containing 5a
chr22_-_24297510 0.27 ENSDART00000163297
si:ch211-117l17.6
si:ch211-117l17.6
chr2_+_38881165 0.26 ENSDART00000141850
carmil3
capping protein regulator and myosin 1 linker 3
chr21_-_37790727 0.26 ENSDART00000162907
gabrb4
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr5_+_2815021 0.25 ENSDART00000020472
hpda
4-hydroxyphenylpyruvate dioxygenase a
chr21_-_21148623 0.24 ENSDART00000184364
ank1b
ankyrin 1, erythrocytic b
chr22_-_16997475 0.24 ENSDART00000090237
nfia
nuclear factor I/A
chr5_-_71838520 0.24 ENSDART00000174396
CU927890.1

chr15_-_24884784 0.24 ENSDART00000181808
aipl1
aryl hydrocarbon receptor interacting protein-like 1
chr22_-_16997887 0.24 ENSDART00000138233
nfia
nuclear factor I/A
chr19_-_3878548 0.24 ENSDART00000168377
ENSDART00000172271
thrap3b
thyroid hormone receptor associated protein 3b
chr7_-_26518086 0.23 ENSDART00000058913
eif4a1a
eukaryotic translation initiation factor 4A1A
chr1_+_58282449 0.22 ENSDART00000131475
si:dkey-222h21.7
si:dkey-222h21.7
chr4_-_2727491 0.22 ENSDART00000141760
ENSDART00000039083
ENSDART00000134442
slco1c1
solute carrier organic anion transporter family, member 1C1
chr17_-_14705039 0.21 ENSDART00000154281
ENSDART00000123550
ptp4a2a
protein tyrosine phosphatase type IVA, member 2a
chr21_+_42226113 0.21 ENSDART00000170362
GABRB2 (1 of many)
gamma-aminobutyric acid type A receptor beta2 subunit
chr19_+_7506380 0.20 ENSDART00000182837
prcc
papillary renal cell carcinoma (translocation-associated)
chr22_+_24215007 0.20 ENSDART00000162227
glrx2
glutaredoxin 2
chr21_-_21594841 0.19 ENSDART00000132490
or133-2
odorant receptor, family H, subfamily 133, member 2
chr21_-_35419486 0.19 ENSDART00000138529
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr25_+_19947298 0.17 ENSDART00000067648
kcna6a
potassium voltage-gated channel, shaker-related, subfamily, member 6 a
chr9_+_25776194 0.16 ENSDART00000144499
zeb2a
zinc finger E-box binding homeobox 2a
chr1_+_20069535 0.16 ENSDART00000088653
prss12
protease, serine, 12 (neurotrypsin, motopsin)
chr6_+_52869892 0.16 ENSDART00000146143
si:dkeyp-3f10.16
si:dkeyp-3f10.16
chr18_+_34225520 0.15 ENSDART00000126115
v2rl1
vomeronasal 2 receptor, l1
chr25_+_36329623 0.13 ENSDART00000073405
zgc:173552
zgc:173552
chr16_+_33144112 0.13 ENSDART00000183149
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr8_+_14792830 0.12 ENSDART00000139972
cacna1ea
calcium channel, voltage-dependent, R type, alpha 1E subunit a
chr16_+_36906693 0.12 ENSDART00000160645
si:ch73-215d9.1
si:ch73-215d9.1
chr6_-_14038804 0.12 ENSDART00000184606
ENSDART00000184609
etv5b
ets variant 5b
chr8_+_18044257 0.11 ENSDART00000029255
glis1b
GLIS family zinc finger 1b
chr18_+_17151916 0.10 ENSDART00000175488
trhr2
thyrotropin releasing hormone receptor 2
chr12_+_20700961 0.10 ENSDART00000016099
si:ch211-119c20.2
si:ch211-119c20.2
chr22_+_30184039 0.10 ENSDART00000049075
add3a
adducin 3 (gamma) a
chr16_+_30933044 0.09 ENSDART00000184453
gstk2
glutathione S-transferase kappa 2
chr6_-_8480815 0.09 ENSDART00000162300
rasal3
RAS protein activator like 3
chr22_+_10676981 0.09 ENSDART00000138016
hyal2b
hyaluronoglucosaminidase 2b
chr16_+_33144306 0.09 ENSDART00000101953
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr1_-_22370660 0.08 ENSDART00000127506
si:ch73-380n15.2
si:ch73-380n15.2
chr7_-_31941330 0.08 ENSDART00000144682
bdnf
brain-derived neurotrophic factor
chr16_+_38159758 0.07 ENSDART00000058666
ENSDART00000112165
pi4kb
phosphatidylinositol 4-kinase, catalytic, beta
chr5_+_21891305 0.07 ENSDART00000136788
si:ch73-92i20.1
si:ch73-92i20.1
chr4_-_55227527 0.07 ENSDART00000184323
ENSDART00000148091
si:dkey-61p9.9
si:dkey-61p9.9
chr25_-_3892686 0.07 ENSDART00000043172
tmem258
transmembrane protein 258
chr6_+_55285578 0.06 ENSDART00000180183
zgc:109913
zgc:109913
chr13_+_27329556 0.06 ENSDART00000140085
mb21d1
Mab-21 domain containing 1
chr4_-_23083187 0.05 ENSDART00000009768
magi2a
membrane associated guanylate kinase, WW and PDZ domain containing 2a
chr14_+_36497250 0.04 ENSDART00000184727
TENM3
si:dkey-237h12.3
chr4_-_23082985 0.03 ENSDART00000133644
magi2a
membrane associated guanylate kinase, WW and PDZ domain containing 2a
chr25_-_7887274 0.03 ENSDART00000157276
si:ch73-151m17.5
si:ch73-151m17.5
chr14_+_23811808 0.03 ENSDART00000014411
kctd16a
potassium channel tetramerization domain containing 16a
chr3_-_36210344 0.02 ENSDART00000025326
csnk1da
casein kinase 1, delta a
chr7_+_20966434 0.01 ENSDART00000185570
efnb3b
ephrin-B3b
chr16_-_16761164 0.00 ENSDART00000135872
si:dkey-27n14.1
si:dkey-27n14.1

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc13a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0032060 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.3 1.0 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.3 0.8 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 0.8 GO:0048340 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.2 0.7 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.2 0.7 GO:0072149 visceral serous pericardium development(GO:0061032) glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.1 0.4 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 1.3 GO:0044030 regulation of DNA methylation(GO:0044030)
0.1 1.6 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 1.3 GO:0042664 negative regulation of endodermal cell fate specification(GO:0042664)
0.1 0.9 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.5 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.1 0.5 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.1 4.6 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.6 GO:0032438 melanosome organization(GO:0032438)
0.1 0.5 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.3 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.1 0.6 GO:0030431 sleep(GO:0030431)
0.0 1.1 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.3 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.4 GO:0014823 response to activity(GO:0014823)
0.0 0.4 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.0 0.5 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 1.9 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.4 GO:0045661 regulation of myoblast differentiation(GO:0045661)
0.0 0.2 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.6 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 4.6 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.1 GO:0035108 limb morphogenesis(GO:0035108)
0.0 1.6 GO:0033333 fin development(GO:0033333)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 1.0 GO:0031101 fin regeneration(GO:0031101)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 4.6 GO:0005861 troponin complex(GO:0005861)
0.1 0.4 GO:0016600 flotillin complex(GO:0016600)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.9 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 1.6 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0047325 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
0.3 0.8 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 1.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.4 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.9 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 1.6 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 0.7 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.2 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.1 0.5 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.4 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.4 GO:0005035 death receptor activity(GO:0005035)
0.0 1.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.2 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.5 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.1 GO:0042165 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
0.0 0.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 2.7 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.0 0.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation