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PRJNA195909:zebrafish embryo and larva development

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Results for hoxc6a+hoxc6b

Z-value: 1.00

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Transcription factors associated with hoxc6a+hoxc6b

Gene Symbol Gene ID Gene Info
hoxc6a
ENSDARG00000070343 homeobox C6a
hoxc6b
ENSDARG00000101954 homeobox C6b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc6bdr11_v1_chr11_+_2198831_2198831-0.694.0e-02Click!
hoxc6adr11_v1_chr23_+_36115541_36115541-0.551.3e-01Click!

Activity profile of hoxc6a+hoxc6b motif

Sorted Z-values of hoxc6a+hoxc6b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_22320738 1.76 ENSDART00000073566
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr8_-_53044300 1.61 ENSDART00000191653
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr20_+_54299419 1.30 ENSDART00000056089
ENSDART00000193107
si:zfos-1505d6.3
si:zfos-1505d6.3
chr20_+_54309148 1.26 ENSDART00000099360
zp2.1
zona pellucida glycoprotein 2, tandem duplicate 1
chr20_+_54304800 1.23 ENSDART00000121661
zp2.6
zona pellucida glycoprotein 2, tandem duplicate 6
chr10_-_34916208 1.19 ENSDART00000187371
ccna1
cyclin A1
chr25_-_21031007 0.99 ENSDART00000138985
gnaia
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr23_+_1029450 0.90 ENSDART00000189196
si:zfos-905g2.1
si:zfos-905g2.1
chr2_-_31833347 0.87 ENSDART00000109460
nol7
nucleolar protein 7
chr16_+_29509133 0.86 ENSDART00000112116
ctss2.1
cathepsin S, ortholog2, tandem duplicate 1
chr21_-_44081540 0.72 ENSDART00000130833
FO704810.1

chr17_+_30369396 0.66 ENSDART00000076611
greb1
growth regulation by estrogen in breast cancer 1
chr25_-_37186894 0.66 ENSDART00000191647
ENSDART00000182095
tdrd12
tudor domain containing 12
chr21_+_43172506 0.63 ENSDART00000121725
zcchc10
zinc finger, CCHC domain containing 10
chr2_-_15324837 0.61 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr7_+_24573721 0.61 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
si:dkeyp-75h12.7
chr2_+_56657804 0.60 ENSDART00000113964
POLR2E (1 of many)
RNA polymerase II subunit E
chr2_+_10878406 0.58 ENSDART00000091497
tceanc2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr22_-_16154771 0.57 ENSDART00000009464
slc30a7
solute carrier family 30 (zinc transporter), member 7
chr23_-_18024543 0.56 ENSDART00000139695
pm20d1.1
peptidase M20 domain containing 1, tandem duplicate 1
chr5_-_37103487 0.56 ENSDART00000149211
il13ra2
interleukin 13 receptor, alpha 2
chr15_-_43284021 0.55 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr23_-_18707418 0.53 ENSDART00000144668
ENSDART00000141205
ENSDART00000016765
zgc:103759
zgc:103759
chr5_+_41477954 0.53 ENSDART00000185871
pias2
protein inhibitor of activated STAT, 2
chr22_-_36530902 0.53 ENSDART00000056188
polr2h
info polymerase (RNA) II (DNA directed) polypeptide H
chr14_-_48765262 0.53 ENSDART00000166463
cnot6b
CCR4-NOT transcription complex, subunit 6b
chr2_+_15048410 0.52 ENSDART00000058484
cnn3b
calponin 3, acidic b
chr2_+_31833997 0.51 ENSDART00000066788
epdr1
ependymin related 1
chr3_-_19368435 0.48 ENSDART00000132987
s1pr5a
sphingosine-1-phosphate receptor 5a
chr13_-_52089003 0.48 ENSDART00000187600
tmem254
transmembrane protein 254
chr19_+_10592778 0.47 ENSDART00000135488
ENSDART00000151624
si:dkey-211g8.5
si:dkey-211g8.5
chr1_-_9195629 0.46 ENSDART00000143587
ENSDART00000192174
ern2
endoplasmic reticulum to nucleus signaling 2
chr7_-_5375214 0.46 ENSDART00000033316
vangl2
VANGL planar cell polarity protein 2
chr10_-_7386475 0.46 ENSDART00000167963
nrg1
neuregulin 1
chr24_+_34113424 0.45 ENSDART00000105572
gbx1
gastrulation brain homeobox 1
chr16_-_7793457 0.45 ENSDART00000113483
trim71
tripartite motif containing 71, E3 ubiquitin protein ligase
chr24_+_21514283 0.45 ENSDART00000007066
cdk8
cyclin-dependent kinase 8
chr3_-_59297532 0.44 ENSDART00000187991
CABZ01053748.1

chr4_-_49582758 0.44 ENSDART00000180834
ENSDART00000187608
si:dkey-159n16.2
si:dkey-159n16.2
chr6_-_43283122 0.43 ENSDART00000186022
frmd4ba
FERM domain containing 4Ba
chr16_-_42965192 0.43 ENSDART00000113714
mtx1a
metaxin 1a
chr16_+_54209504 0.42 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr11_-_44979281 0.42 ENSDART00000190972
ldb1b
LIM-domain binding 1b
chr1_+_22851261 0.41 ENSDART00000193925
gtf2e2
general transcription factor IIE, polypeptide 2, beta
chr8_+_26874924 0.41 ENSDART00000141794
rimkla
ribosomal modification protein rimK-like family member A
chr24_-_38657683 0.40 ENSDART00000154843
si:ch1073-164k15.3
si:ch1073-164k15.3
chr5_+_41477526 0.39 ENSDART00000153567
pias2
protein inhibitor of activated STAT, 2
chr2_-_10877765 0.39 ENSDART00000100607
cdc7
cell division cycle 7 homolog (S. cerevisiae)
chr5_-_51198430 0.39 ENSDART00000132503
ENSDART00000097473
ENSDART00000165870
snapc4
small nuclear RNA activating complex, polypeptide 4
chr17_+_51682429 0.38 ENSDART00000004379
nol10
nucleolar protein 10
chr23_-_35790235 0.38 ENSDART00000142369
ENSDART00000141141
ENSDART00000011004
mfsd5
major facilitator superfamily domain containing 5
chr11_+_17984167 0.37 ENSDART00000020283
ENSDART00000188329
rpusd4
RNA pseudouridylate synthase domain containing 4
chr18_+_13275735 0.37 ENSDART00000148127
plcg2
phospholipase C, gamma 2
chr3_+_7808459 0.37 ENSDART00000162374
hook2
hook microtubule-tethering protein 2
chr21_-_1640547 0.37 ENSDART00000151041
zgc:152948
zgc:152948
chr11_+_17984354 0.37 ENSDART00000179986
rpusd4
RNA pseudouridylate synthase domain containing 4
chr22_+_508290 0.37 ENSDART00000135403
nuak2
NUAK family, SNF1-like kinase, 2
chr8_-_39884359 0.36 ENSDART00000131372
mlec
malectin
chr21_-_36571804 0.36 ENSDART00000138129
wwc1
WW and C2 domain containing 1
chr7_+_7696665 0.36 ENSDART00000091099
ino80b
INO80 complex subunit B
chr3_-_31158382 0.35 ENSDART00000076764
ENSDART00000076796
smg1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr10_+_11767791 0.34 ENSDART00000092047
ppwd1
peptidylprolyl isomerase domain and WD repeat containing 1
chr17_-_25831569 0.34 ENSDART00000148743
hhat
hedgehog acyltransferase
chr8_+_36560019 0.34 ENSDART00000136418
ENSDART00000061378
ENSDART00000185237
sf3a1
splicing factor 3a, subunit 1
chr4_-_5108844 0.33 ENSDART00000132666
ENSDART00000136096
tmem209
transmembrane protein 209
chr6_+_12527725 0.33 ENSDART00000149328
stk24b
serine/threonine kinase 24b (STE20 homolog, yeast)
chr4_+_57881965 0.31 ENSDART00000162234
si:dkeyp-44b5.4
si:dkeyp-44b5.4
chr16_+_40024883 0.31 ENSDART00000110100
hint3
histidine triad nucleotide binding protein 3
chr4_+_76926059 0.31 ENSDART00000136192
si:dkey-240n22.6
si:dkey-240n22.6
chr10_-_13343831 0.30 ENSDART00000135941
il11ra
interleukin 11 receptor, alpha
chr8_-_19246342 0.30 ENSDART00000147172
abhd17ab
abhydrolase domain containing 17Ab
chr13_+_35528607 0.30 ENSDART00000075414
ENSDART00000112947
wdr27
WD repeat domain 27
chr23_+_4709607 0.30 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
raf1a
raf1a
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr19_-_5769553 0.29 ENSDART00000175003
si:ch211-264f5.6
si:ch211-264f5.6
chr3_+_23092762 0.29 ENSDART00000142884
ENSDART00000024136
gngt2a
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr7_-_67248829 0.28 ENSDART00000192442
znf143a
zinc finger protein 143a
chr12_-_35944654 0.28 ENSDART00000162579
ENSDART00000164199
dnai2a
dynein, axonemal, intermediate chain 2a
chr4_+_2482046 0.28 ENSDART00000103371
zdhhc17
zinc finger, DHHC-type containing 17
chr19_-_5769728 0.28 ENSDART00000133106
si:ch211-264f5.6
si:ch211-264f5.6
chr12_-_4532066 0.28 ENSDART00000092687
trpm4b.2
transient receptor potential cation channel, subfamily M, member 4b, transient receptor potential cation channel, subfamily M, member 4b, tandem duplicate 2
chr16_-_36748374 0.28 ENSDART00000133310
pik3r4
phosphoinositide-3-kinase, regulatory subunit 4
chr18_+_35128685 0.27 ENSDART00000151579
si:ch211-195m9.3
si:ch211-195m9.3
chr2_-_17392799 0.27 ENSDART00000136470
ENSDART00000141188
st3gal3b
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr15_+_29140126 0.26 ENSDART00000060034
zgc:113149
zgc:113149
chr10_-_11261565 0.26 ENSDART00000146727
ptbp3
polypyrimidine tract binding protein 3
chr1_-_51038885 0.26 ENSDART00000035150
spast
spastin
chr23_-_18913032 0.26 ENSDART00000136678
si:ch211-209j10.6
si:ch211-209j10.6
chr2_-_17393216 0.26 ENSDART00000123137
st3gal3b
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr4_-_11064073 0.26 ENSDART00000150760
si:dkey-21h14.8
si:dkey-21h14.8
chr7_-_8712148 0.26 ENSDART00000065488
tex261
testis expressed 261
chr9_-_32177117 0.24 ENSDART00000078568
sf3b1
splicing factor 3b, subunit 1
chr22_-_24791505 0.24 ENSDART00000136837
vtg4
vitellogenin 4
chr4_-_2219705 0.24 ENSDART00000131046
si:ch73-278m9.1
si:ch73-278m9.1
chr5_+_29851433 0.24 ENSDART00000143434
ubash3ba
ubiquitin associated and SH3 domain containing Ba
chr21_+_37090585 0.24 ENSDART00000182971
znf346
zinc finger protein 346
chr3_+_38540411 0.23 ENSDART00000154943
si:dkey-7f16.3
si:dkey-7f16.3
chr3_+_1637358 0.23 ENSDART00000180266
CR394546.5

chr11_-_10456387 0.23 ENSDART00000011087
ENSDART00000081827
ect2
epithelial cell transforming 2
chr15_-_26931541 0.23 ENSDART00000027563
ccdc9
coiled-coil domain containing 9
chr16_+_4654333 0.23 ENSDART00000167665
LIN28A
si:ch1073-284b18.2
chr1_+_27977297 0.23 ENSDART00000180692
ENSDART00000166819
sugt1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
chr22_+_2751887 0.23 ENSDART00000133652
si:dkey-20i20.11
si:dkey-20i20.11
chr25_-_27621268 0.23 ENSDART00000146205
ENSDART00000073511
hyal6
hyaluronoglucosaminidase 6
chr24_-_38110779 0.23 ENSDART00000147783
crp
c-reactive protein, pentraxin-related
chr5_+_32076109 0.23 ENSDART00000051357
ENSDART00000144510
zmat5
zinc finger, matrin-type 5
chr11_+_45436703 0.23 ENSDART00000168295
ENSDART00000173293
sos1
son of sevenless homolog 1 (Drosophila)
chr15_-_2754056 0.23 ENSDART00000129380
ppp5c
protein phosphatase 5, catalytic subunit
chr13_+_33268657 0.22 ENSDART00000002095
tmem39b
transmembrane protein 39B
chr15_+_857148 0.21 ENSDART00000156949
si:dkey-7i4.13
si:dkey-7i4.13
chr16_+_13818743 0.21 ENSDART00000090191
flcn
folliculin
chr19_+_43885770 0.21 ENSDART00000135599
lypla2
lysophospholipase II
chr5_-_13251907 0.21 ENSDART00000176774
ENSDART00000030553
top3b
DNA topoisomerase III beta
chr3_+_40164129 0.20 ENSDART00000102526
gfer
growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)
chr24_+_9693951 0.20 ENSDART00000082411
topbp1
DNA topoisomerase II binding protein 1
chr13_-_50366950 0.20 ENSDART00000098209
sirt1
sirtuin 1
chr24_+_15020402 0.20 ENSDART00000148102
dok6
docking protein 6
chr5_+_61459422 0.20 ENSDART00000050902
polr2j
polymerase (RNA) II (DNA directed) polypeptide J
chr12_+_47698356 0.20 ENSDART00000112010
lzts2b
leucine zipper, putative tumor suppressor 2b
chr24_+_28953089 0.20 ENSDART00000153761
rnpc3
RNA-binding region (RNP1, RRM) containing 3
chr22_-_21676364 0.19 ENSDART00000183668
tle2b
transducin like enhancer of split 2b
chr8_+_29635968 0.18 ENSDART00000139029
ENSDART00000091409
smarcad1a
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a
chr11_+_1602916 0.18 ENSDART00000184434
ENSDART00000112597
ENSDART00000192165
si:dkey-40c23.2
si:dkey-40c23.3
si:dkey-40c23.2
si:dkey-40c23.3
chr18_+_20481982 0.18 ENSDART00000128139
kbtbd4
kelch repeat and BTB (POZ) domain containing 4
chr1_-_42289704 0.17 ENSDART00000150124
si:ch211-71k14.1
si:ch211-71k14.1
chr22_-_26865181 0.17 ENSDART00000138311
hmox2a
heme oxygenase 2a
chr5_+_19343880 0.17 ENSDART00000148130
acacb
acetyl-CoA carboxylase beta
chr7_+_26534131 0.17 ENSDART00000173980
si:dkey-62k3.5
si:dkey-62k3.5
chr16_-_44945224 0.17 ENSDART00000156921
ncam3
neural cell adhesion molecule 3
chr11_-_10456553 0.17 ENSDART00000169509
ENSDART00000185574
ENSDART00000188276
ect2
epithelial cell transforming 2
chr8_+_31717175 0.17 ENSDART00000013434
oxct1a
3-oxoacid CoA transferase 1a
chr4_-_43640507 0.17 ENSDART00000150700
si:dkey-29p23.2
si:dkey-29p23.2
chr20_+_25586099 0.17 ENSDART00000063122
ENSDART00000134047
cyp2p10
cytochrome P450, family 2, subfamily P, polypeptide 10
chr23_-_19140781 0.16 ENSDART00000143580
si:ch73-381f5.2
si:ch73-381f5.2
chr4_+_33012407 0.16 ENSDART00000151873
si:dkey-26h11.2
si:dkey-26h11.2
chr23_-_36418708 0.15 ENSDART00000132273
znf740b
zinc finger protein 740b
chr1_+_47499888 0.15 ENSDART00000027624
stn1
STN1, CST complex subunit
chr2_+_2169337 0.15 ENSDART00000179939
higd1a
HIG1 hypoxia inducible domain family, member 1A
chr1_+_49668423 0.15 ENSDART00000150880
tsga10
testis specific, 10
chr6_-_12588044 0.15 ENSDART00000047896
slc15a1b
solute carrier family 15 (oligopeptide transporter), member 1b
chr1_+_32051581 0.15 ENSDART00000146602
sts
steroid sulfatase (microsomal), isozyme S
chr13_+_9468535 0.15 ENSDART00000135088
ENSDART00000164270
ENSDART00000099619
ENSDART00000164656
HTRA2 (1 of many)
si:dkey-265c15.6
chr16_+_28728347 0.15 ENSDART00000149240
si:dkey-24i24.3
si:dkey-24i24.3
chr13_+_646700 0.15 ENSDART00000006892
tp53bp2a
tumor protein p53 binding protein, 2a
chr8_+_31716872 0.15 ENSDART00000161121
oxct1a
3-oxoacid CoA transferase 1a
chr21_-_26028205 0.14 ENSDART00000034875
sdf2
stromal cell-derived factor 2
chr3_+_29179329 0.14 ENSDART00000085216
ENSDART00000190136
cacna1i
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr25_-_25058508 0.14 ENSDART00000087570
ENSDART00000178891
FQ311928.1

chr24_+_19415124 0.14 ENSDART00000186931
sulf1
sulfatase 1
chr22_-_5252005 0.13 ENSDART00000132942
ENSDART00000081801
ncln
nicalin
chr4_-_46915962 0.13 ENSDART00000169555
si:ch211-134c10.1
si:ch211-134c10.1
chr8_+_50953776 0.13 ENSDART00000013870
zgc:56596
zgc:56596
chr17_+_20589553 0.13 ENSDART00000154447
si:ch73-288o11.4
si:ch73-288o11.4
chr10_+_29850330 0.13 ENSDART00000168898
hspa8
heat shock protein 8
chr13_+_15656042 0.13 ENSDART00000134240
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr4_-_63769637 0.13 ENSDART00000158757
znf1098
zinc finger protein 1098
chr7_-_11596450 0.12 ENSDART00000173863
stard5
StAR-related lipid transfer (START) domain containing 5
chr4_-_43388943 0.12 ENSDART00000150796
si:dkey-29j8.2
si:dkey-29j8.2
chr22_-_9183944 0.12 ENSDART00000188599
si:ch211-213a13.5
si:ch211-213a13.5
chr16_-_27677930 0.12 ENSDART00000145991
tbrg4
transforming growth factor beta regulator 4
chr23_-_16485190 0.12 ENSDART00000155038
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr5_+_38040407 0.12 ENSDART00000139936
si:dkey-111e8.4
si:dkey-111e8.4
chr10_+_11261576 0.11 ENSDART00000155333
hsdl2
hydroxysteroid dehydrogenase like 2
chr13_-_12602920 0.11 ENSDART00000102311
lrit3b
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr7_+_66884291 0.11 ENSDART00000187499
sbf2
SET binding factor 2
chr10_+_22527715 0.11 ENSDART00000134864
gigyf1b
GRB10 interacting GYF protein 1b
chr7_+_66884570 0.11 ENSDART00000082664
sbf2
SET binding factor 2
chr7_-_50410524 0.11 ENSDART00000083346
hypk
huntingtin interacting protein K
chr20_+_11731039 0.10 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
si:ch211-155o21.3
chr6_+_7533601 0.10 ENSDART00000057823
pa2g4a
proliferation-associated 2G4, a
chr11_+_11267493 0.10 ENSDART00000148425
ptp4a1
protein tyrosine phosphatase type IVA, member 1
chr1_+_513986 0.10 ENSDART00000109083
ENSDART00000081945
txnl4b
thioredoxin-like 4B
chr8_-_45867358 0.10 ENSDART00000132810
adam9
ADAM metallopeptidase domain 9
chr19_+_1688727 0.09 ENSDART00000115136
ENSDART00000166744
dennd3a
DENN/MADD domain containing 3a
chr17_-_29224908 0.09 ENSDART00000156288
si:dkey-28g23.6
si:dkey-28g23.6
chr4_-_19921410 0.08 ENSDART00000184359
ENSDART00000179965
BX323820.1

chr1_-_513762 0.08 ENSDART00000148162
ENSDART00000144606
trmt10c
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr2_+_19522082 0.08 ENSDART00000146098
pimr49
Pim proto-oncogene, serine/threonine kinase, related 49
chr7_-_34448076 0.08 ENSDART00000170935
nr1h3
nuclear receptor subfamily 1, group H, member 3
chr24_+_21540842 0.08 ENSDART00000091529
wasf3b
WAS protein family, member 3b
chr6_+_40591149 0.08 ENSDART00000189060
ENSDART00000188298
frs3
fibroblast growth factor receptor substrate 3
chr7_+_4474880 0.08 ENSDART00000143528
si:dkey-83f18.14
si:dkey-83f18.14
chr17_+_26611929 0.08 ENSDART00000166450
ENSDART00000087023
ttc7b
tetratricopeptide repeat domain 7B
chr9_+_24065855 0.07 ENSDART00000161468
ENSDART00000171577
ENSDART00000172743
ENSDART00000159324
ENSDART00000079689
ENSDART00000023196
ENSDART00000101577
lrrfip1a
leucine rich repeat (in FLII) interacting protein 1a
chr13_-_39736938 0.07 ENSDART00000141645
zgc:171482
zgc:171482
chr12_-_28363111 0.07 ENSDART00000016283
ENSDART00000164156
psmd11b
proteasome 26S subunit, non-ATPase 11b
chr20_-_34750363 0.07 ENSDART00000152845
znf395b
zinc finger protein 395b
chr13_-_9467944 0.07 ENSDART00000136582
pimr152
Pim proto-oncogene, serine/threonine kinase, related 152
chr4_-_67980261 0.07 ENSDART00000182305
si:ch211-223k15.1
si:ch211-223k15.1
chr8_-_36287046 0.07 ENSDART00000162877
si:busm1-194e12.11
si:busm1-194e12.11
chr10_+_34047352 0.07 ENSDART00000169333
HTRA2 (1 of many)
si:dkey-10b15.8
chr7_+_4657987 0.07 ENSDART00000144321
ENSDART00000142344
si:dkey-83f18.2
si:dkey-83f18.2
chr16_-_41515662 0.07 ENSDART00000166201
ENSDART00000127243
siglec15l
sialic acid binding Ig-like lectin 15, like
chr6_-_52788213 0.06 ENSDART00000179880
rbpjl
recombination signal binding protein for immunoglobulin kappa J region-like
chr1_-_22851481 0.06 ENSDART00000054386
qdprb1
quinoid dihydropteridine reductase b1
chr25_+_29474982 0.06 ENSDART00000130410
il17rel
interleukin 17 receptor E-like
chr2_-_23603061 0.05 ENSDART00000132072
si:dkey-58b18.9
si:dkey-58b18.9
chr16_-_21140097 0.05 ENSDART00000145837
ENSDART00000146500
si:dkey-271j15.3
si:dkey-271j15.3
chr17_-_16422654 0.05 ENSDART00000150149
tdp1
tyrosyl-DNA phosphodiesterase 1
chr3_-_31254379 0.05 ENSDART00000189376
apnl
actinoporin-like protein
chr20_-_34750045 0.04 ENSDART00000186130
znf395b
zinc finger protein 395b

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc6a+hoxc6b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.2 0.5 GO:0060945 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.1 0.6 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.1 0.7 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 0.5 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.5 GO:0000012 single strand break repair(GO:0000012)
0.1 0.3 GO:0002369 T cell cytokine production(GO:0002369)
0.1 0.5 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 0.5 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
0.1 0.3 GO:0051230 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.1 0.5 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.1 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.4 GO:0032475 otolith formation(GO:0032475)
0.1 0.2 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
0.0 0.3 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.5 GO:0016074 snoRNA metabolic process(GO:0016074)
0.0 0.2 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.5 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.4 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.9 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.2 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.4 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:1904478 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.2 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.0 0.7 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 1.2 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 1.6 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.2 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.1 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.2 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.2 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.0 0.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.1 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.4 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0045124 regulation of bone resorption(GO:0045124)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0050821 protein stabilization(GO:0050821)
0.0 0.0 GO:0045903 positive regulation of translational fidelity(GO:0045903)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.2 0.5 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.4 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.3 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.4 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 0.2 GO:1990879 CST complex(GO:1990879)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 1.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.0 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.1 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.2 0.5 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.1 0.4 GO:0072591 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.1 0.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 1.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.5 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 0.9 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.3 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.6 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.5 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.3 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.2 GO:0042936 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.1 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.3 GO:0002039 p53 binding(GO:0002039)
0.0 1.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.0 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.7 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.4 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 0.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 0.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID EPO PATHWAY EPO signaling pathway
0.0 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.7 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.4 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle