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PRJNA195909:zebrafish embryo and larva development

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Results for ikzf1

Z-value: 2.04

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Transcription factors associated with ikzf1

Gene Symbol Gene ID Gene Info
ikzf1
ENSDARG00000013539 IKAROS family zinc finger 1 (Ikaros)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ikzf1dr11_v1_chr13_-_15982707_159827070.732.7e-02Click!

Activity profile of ikzf1 motif

Sorted Z-values of ikzf1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_32817274 3.50 ENSDART00000142582
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr5_-_71722257 3.28 ENSDART00000013404
ak1
adenylate kinase 1
chr25_+_29161609 3.11 ENSDART00000180752
pkmb
pyruvate kinase M1/2b
chr7_-_8416750 2.84 ENSDART00000181857
jac1
jacalin 1
chr11_-_21030070 2.77 ENSDART00000186322
fmoda
fibromodulin a
chr5_+_32345187 2.48 ENSDART00000147132
c9
complement component 9
chr5_+_32222303 2.47 ENSDART00000051362
myhc4
myosin heavy chain 4
chr12_+_25085751 2.43 ENSDART00000170466
gch2
GTP cyclohydrolase 2
chr21_+_7582036 2.28 ENSDART00000135485
ENSDART00000027268
otpa
orthopedia homeobox a
chr12_-_16636627 2.22 ENSDART00000128811
si:dkey-239j18.3
si:dkey-239j18.3
chr20_+_20637866 2.21 ENSDART00000060203
ENSDART00000079079
rtn1b
reticulon 1b
chr16_+_20915319 2.16 ENSDART00000079383
hoxa9b
homeobox A9b
chr5_-_28606916 2.00 ENSDART00000026107
ENSDART00000137717
tnc
tenascin C
chr7_-_24472991 1.99 ENSDART00000121684
nat8l
N-acetyltransferase 8-like
chr7_-_2039060 1.95 ENSDART00000173879
si:cabz01007794.1
si:cabz01007794.1
chr13_-_39159810 1.92 ENSDART00000131508
col9a1b
collagen, type IX, alpha 1b
chr20_+_20638034 1.92 ENSDART00000189759
rtn1b
reticulon 1b
chr12_-_16720196 1.90 ENSDART00000187639
si:dkey-26g8.4
si:dkey-26g8.4
chr25_+_18563476 1.86 ENSDART00000170841
cav1
caveolin 1
chr21_-_25741096 1.86 ENSDART00000181756
cldnh
claudin h
chr17_+_25414033 1.81 ENSDART00000001691
tdh2
L-threonine dehydrogenase 2
chr1_+_135903 1.73 ENSDART00000124837
f10
coagulation factor X
chr3_+_30921246 1.72 ENSDART00000076850
cldni
claudin i
chr6_-_39764995 1.71 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr7_-_35432901 1.71 ENSDART00000026712
mmp2
matrix metallopeptidase 2
chr13_-_39160018 1.69 ENSDART00000168795
col9a1b
collagen, type IX, alpha 1b
chr17_+_23300827 1.69 ENSDART00000058745
zgc:165461
zgc:165461
chr7_-_8438657 1.68 ENSDART00000173054
si:dkeyp-32g11.8
si:dkeyp-32g11.8
chr2_+_42724404 1.68 ENSDART00000075392
basp1
brain abundant, membrane attached signal protein 1
chr12_-_16619449 1.67 ENSDART00000182074
ctslb
cathepsin Lb
chr23_-_26077038 1.64 ENSDART00000126299
gdi1
GDP dissociation inhibitor 1
chr15_-_23376541 1.59 ENSDART00000078570
c1qtnf5
C1q and TNF related 5
chr12_-_16595177 1.58 ENSDART00000133962
si:dkey-239j18.2
si:dkey-239j18.2
chr17_+_2549503 1.57 ENSDART00000156843
si:dkey-248g15.3
si:dkey-248g15.3
chr13_-_36391496 1.57 ENSDART00000100217
ENSDART00000140243
actn1
actinin, alpha 1
chr25_-_31396479 1.54 ENSDART00000156828
prr33
proline rich 33
chr5_-_41831646 1.50 ENSDART00000134326
si:dkey-65b12.6
si:dkey-65b12.6
chr18_-_14860435 1.48 ENSDART00000018502
mapk12a
mitogen-activated protein kinase 12a
chr14_-_17068511 1.47 ENSDART00000163766
phox2bb
paired-like homeobox 2bb
chr7_-_58098814 1.45 ENSDART00000147287
ENSDART00000043984
ank2b
ankyrin 2b, neuronal
chr12_+_42574148 1.44 ENSDART00000157855
ebf3a
early B cell factor 3a
chr2_-_31936966 1.43 ENSDART00000169484
ENSDART00000192492
ENSDART00000027689
amph
amphiphysin
chr21_+_19834072 1.42 ENSDART00000147555
ccdc80l2
coiled-coil domain containing 80 like 2
chr18_+_30847237 1.42 ENSDART00000012374
foxf1
forkhead box F1
chr10_+_21786656 1.39 ENSDART00000185851
ENSDART00000167219
pcdh1g26
protocadherin 1 gamma 26
chr7_-_8490886 1.37 ENSDART00000159012
jac6
jacalin 6
chr6_+_6491013 1.36 ENSDART00000140827
bcl11ab
B cell CLL/lymphoma 11Ab
chr5_-_31712399 1.35 ENSDART00000141328
pip5kl1
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr14_-_51855047 1.34 ENSDART00000088912
cplx1
complexin 1
chr10_-_8358396 1.34 ENSDART00000059322
csgalnact1a
chondroitin sulfate N-acetylgalactosaminyltransferase 1a
chr16_-_31717851 1.29 ENSDART00000169109
rbp5
retinol binding protein 1a, cellular
chr1_+_51496862 1.28 ENSDART00000150433
meis1a
Meis homeobox 1 a
chr17_+_10242166 1.28 ENSDART00000170420
clec14a
C-type lectin domain containing 14A
chr1_-_44434707 1.28 ENSDART00000110148
cryba1l2
crystallin, beta A1, like 2
chr16_+_1353894 1.25 ENSDART00000148426
celf3b
cugbp, Elav-like family member 3b
chr7_-_32833153 1.25 ENSDART00000099871
ENSDART00000099872
slc17a6b
solute carrier family 17 (vesicular glutamate transporter), member 6b
chr1_+_47446032 1.25 ENSDART00000126904
ENSDART00000007262
gja8b
gap junction protein alpha 8 paralog b
chr16_-_46660680 1.24 ENSDART00000159209
ENSDART00000191929
tmem176l.4
transmembrane protein 176l.4
chr21_-_10773344 1.23 ENSDART00000063244
grp
gastrin-releasing peptide
chr15_+_36115955 1.23 ENSDART00000032702
sst1.2
somatostatin 1, tandem duplicate 2
chr15_-_24869826 1.22 ENSDART00000127047
tusc5a
tumor suppressor candidate 5a
chr25_-_15045338 1.22 ENSDART00000161165
ENSDART00000165774
ENSDART00000172538
pax6a
paired box 6a
chr5_-_8164439 1.22 ENSDART00000189912
slc1a3a
solute carrier family 1 (glial high affinity glutamate transporter), member 3a
chr7_+_31879649 1.21 ENSDART00000099789
mybpc3
myosin binding protein C, cardiac
chr5_-_64883082 1.18 ENSDART00000064983
ENSDART00000139066
krt1-c5
keratin, type 1, gene c5
chr23_-_11870962 1.18 ENSDART00000143481
si:dkey-178k16.1
si:dkey-178k16.1
chr5_+_72108241 1.15 ENSDART00000006606
fabp1a
fatty acid binding protein 1a, liver
chr3_+_25154078 1.14 ENSDART00000156973
si:ch211-256m1.8
si:ch211-256m1.8
chr1_+_36436936 1.14 ENSDART00000124112
pou4f2
POU class 4 homeobox 2
chr16_-_31718013 1.13 ENSDART00000190716
rbp5
retinol binding protein 1a, cellular
chr14_-_5678457 1.11 ENSDART00000012116
tlx2
T cell leukemia homeobox 2
chr7_-_43787616 1.09 ENSDART00000179758
cdh11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr1_+_37391141 1.09 ENSDART00000083593
ENSDART00000168647
sparcl1
SPARC-like 1
chr17_+_996509 1.08 ENSDART00000158830
cyp1c2
cytochrome P450, family 1, subfamily C, polypeptide 2
chr17_+_52822422 1.08 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr19_+_12583577 1.08 ENSDART00000151508
ldlrad4a
low density lipoprotein receptor class A domain containing 4a
chr14_-_39031108 1.08 ENSDART00000026194
glra4a
glycine receptor, alpha 4a
chr2_-_21335131 1.08 ENSDART00000057022
klhl40a
kelch-like family member 40a
chr7_+_39386982 1.03 ENSDART00000146702
tnni2b.2
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr5_-_26181863 1.03 ENSDART00000098500
ccdc125
coiled-coil domain containing 125
chr15_-_1822166 1.02 ENSDART00000156883
mmp28
matrix metallopeptidase 28
chr19_-_47452874 1.02 ENSDART00000025931
tfap2e
transcription factor AP-2 epsilon
chr20_+_54738210 1.01 ENSDART00000151399
pak7
p21 protein (Cdc42/Rac)-activated kinase 7
chr23_-_30787932 1.00 ENSDART00000135771
myt1a
myelin transcription factor 1a
chr11_+_41981959 1.00 ENSDART00000055707
her15.1
hairy and enhancer of split-related 15, tandem duplicate 1
chr2_-_34555945 1.00 ENSDART00000056671
brinp2
bone morphogenetic protein/retinoic acid inducible neural-specific 2
chr23_+_36083529 1.00 ENSDART00000053295
ENSDART00000130260
hoxc10a
homeobox C10a
chr25_-_23526058 0.98 ENSDART00000191331
ENSDART00000062930
phlda2
pleckstrin homology-like domain, family A, member 2
chr23_+_6795531 0.98 ENSDART00000092131
si:ch211-117c9.5
si:ch211-117c9.5
chr9_-_21067971 0.97 ENSDART00000004333
tbx15
T-box 15
chr18_+_20494413 0.96 ENSDART00000060295
rapsn
receptor-associated protein of the synapse, 43kD
chr16_+_5156420 0.96 ENSDART00000012053
elovl4a
ELOVL fatty acid elongase 4a
chr9_-_1939232 0.96 ENSDART00000146131
hoxd3a
homeobox D3a
chr10_+_22724059 0.95 ENSDART00000136123
kdm6bb
lysine (K)-specific demethylase 6B, b
chr14_-_17068712 0.93 ENSDART00000170277
phox2bb
paired-like homeobox 2bb
chr1_+_36437585 0.93 ENSDART00000189182
pou4f2
POU class 4 homeobox 2
chr2_-_1518360 0.92 ENSDART00000182788
c8b
complement component 8, beta polypeptide
chr15_-_2632891 0.92 ENSDART00000081840
cldnj
claudin j
chr10_-_25860102 0.90 ENSDART00000080789
trpc4a
transient receptor potential cation channel, subfamily C, member 4a
chr9_+_21402863 0.89 ENSDART00000125357
cx30.3
connexin 30.3
chr19_+_22216778 0.89 ENSDART00000052521
nfatc1
nuclear factor of activated T cells 1
chr13_+_27951688 0.89 ENSDART00000050303
b3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr12_-_3940768 0.89 ENSDART00000134292
zgc:92040
zgc:92040
chr16_+_50100420 0.88 ENSDART00000128167
nr1d2a
nuclear receptor subfamily 1, group D, member 2a
chr9_-_5046315 0.88 ENSDART00000179087
ENSDART00000109954
nr4a2a
nuclear receptor subfamily 4, group A, member 2a
chr15_-_2640966 0.86 ENSDART00000063320
cldne
claudin e
chr18_-_41375120 0.85 ENSDART00000098673
ptx3a
pentraxin 3, long a
chr7_+_8456999 0.85 ENSDART00000172880
jac4
jacalin 4
chr3_+_40170216 0.84 ENSDART00000011568
syngr3a
synaptogyrin 3a
chr23_+_23658474 0.84 ENSDART00000162838
agrn
agrin
chr3_+_41922114 0.84 ENSDART00000138280
lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr5_-_41841675 0.84 ENSDART00000141683
si:dkey-65b12.6
si:dkey-65b12.6
chr1_-_46981134 0.83 ENSDART00000130607
pknox1.2
pbx/knotted 1 homeobox 1.2
chr23_-_4925641 0.82 ENSDART00000140861
ENSDART00000060718
taz
tafazzin
chr16_-_54455573 0.82 ENSDART00000075275
pklr
pyruvate kinase L/R
chr3_-_58644920 0.80 ENSDART00000155953
dhrs7ca
dehydrogenase/reductase (SDR family) member 7Ca
chr5_-_14344647 0.79 ENSDART00000188456
tet3
tet methylcytosine dioxygenase 3
chr5_+_32791245 0.79 ENSDART00000077189
ier5l
immediate early response 5-like
chr18_+_45990394 0.79 ENSDART00000024068
mmp23bb
matrix metallopeptidase 23bb
chr19_-_9829965 0.78 ENSDART00000136842
ENSDART00000142766
cacng8a
calcium channel, voltage-dependent, gamma subunit 8a
chr20_+_1398564 0.78 ENSDART00000002242
leg1.2
liver-enriched gene 1, tandem duplicate 2
chr6_+_39370587 0.78 ENSDART00000157165
ENSDART00000155079
si:dkey-195m11.8
si:dkey-195m11.8
chr12_+_36971952 0.78 ENSDART00000125900
hs3st3b1b
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1b
chr16_+_29492937 0.77 ENSDART00000011497
ctsk
cathepsin K
chr24_-_38816725 0.77 ENSDART00000063231
nog2
noggin 2
chr4_+_25651720 0.77 ENSDART00000100693
ENSDART00000100717
acot16
acyl-CoA thioesterase 16
chr18_-_7400075 0.76 ENSDART00000101250
si:dkey-30c15.13
si:dkey-30c15.13
chr16_+_37470717 0.76 ENSDART00000112003
ENSDART00000188431
ENSDART00000192837
adgrb1a
adhesion G protein-coupled receptor B1a
chr4_-_12914163 0.75 ENSDART00000140002
ENSDART00000145917
ENSDART00000141355
ENSDART00000067135
msrb3
methionine sulfoxide reductase B3
chr5_-_41838354 0.75 ENSDART00000146793
si:dkey-65b12.6
si:dkey-65b12.6
chr8_-_18535822 0.75 ENSDART00000100558
nexn
nexilin (F actin binding protein)
chr18_-_7399767 0.75 ENSDART00000181689
si:dkey-30c15.13
si:dkey-30c15.13
chr5_-_26466169 0.74 ENSDART00000144035
arvcfb
ARVCF, delta catenin family member b
chr23_+_2361184 0.73 ENSDART00000184469
CABZ01048666.1

chr18_+_45796096 0.73 ENSDART00000087070
abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr12_-_30548244 0.71 ENSDART00000193616
zgc:158404
zgc:158404
chr18_-_15911394 0.70 ENSDART00000091339
plekhg7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr19_+_12801940 0.70 ENSDART00000040073
mc5ra
melanocortin 5a receptor
chr14_-_2196267 0.69 ENSDART00000161674
ENSDART00000125674
pcdh2ab8
pcdh2ab9
protocadherin 2 alpha b 8
protocadherin 2 alpha b 9
chr8_-_34762163 0.69 ENSDART00000114080
setd1bb
SET domain containing 1B, b
chr4_-_68913650 0.68 ENSDART00000184297
si:dkey-264f17.5
si:dkey-264f17.5
chr13_-_46991577 0.68 ENSDART00000114748
vip
vasoactive intestinal peptide
chr2_-_689047 0.67 ENSDART00000122732
foxc1a
forkhead box C1a
chr21_+_39100289 0.65 ENSDART00000075958
slc13a2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr7_-_8470860 0.64 ENSDART00000172793
loc564481
hypothetical protein LOC564481
chr2_-_10338759 0.64 ENSDART00000150166
ENSDART00000149584
gng12a
guanine nucleotide binding protein (G protein), gamma 12a
chr17_+_32374876 0.64 ENSDART00000183851
ywhaqb
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b
chr21_-_131236 0.64 ENSDART00000160005
si:ch1073-398f15.1
si:ch1073-398f15.1
chr17_-_14876758 0.64 ENSDART00000155857
nid2a
nidogen 2a (osteonidogen)
chr15_+_42573909 0.64 ENSDART00000181801
CLDN8 (1 of many)
zgc:110333
chr23_+_3616224 0.64 ENSDART00000190917
si:dkey-9l20.3
si:dkey-9l20.3
chr24_-_2900511 0.63 ENSDART00000185674
fam69c
family with sequence similarity 69, member C
chr23_+_21663631 0.63 ENSDART00000066125
dhrs3a
dehydrogenase/reductase (SDR family) member 3a
chr9_+_33145522 0.63 ENSDART00000005879
atp5po
ATP synthase peripheral stalk subunit OSCP
chr12_+_31673588 0.63 ENSDART00000152971
dnmbp
dynamin binding protein
chr15_-_2652640 0.63 ENSDART00000146094
cldnf
claudin f
chr7_+_33314925 0.63 ENSDART00000148590
coro2ba
coronin, actin binding protein, 2Ba
chr15_-_28247583 0.63 ENSDART00000112967
rilp
Rab interacting lysosomal protein
chr5_-_57641257 0.62 ENSDART00000149282
hspb2
heat shock protein, alpha-crystallin-related, b2
chr11_+_10541258 0.62 ENSDART00000132365
b3gnt5a
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr16_+_24842662 0.61 ENSDART00000157333
si:dkey-79d12.6
si:dkey-79d12.6
chr8_+_1009831 0.61 ENSDART00000172414
fabp1b.2
fatty acid binding protein 1b, liver, tandem duplicate 2
chr2_+_6885852 0.60 ENSDART00000016607
rgs5b
regulator of G protein signaling 5b
chr20_+_2039518 0.60 ENSDART00000043157
CABZ01088134.1

chr8_+_20488322 0.60 ENSDART00000036630
zgc:101100
zgc:101100
chr23_-_3674443 0.58 ENSDART00000134830
ENSDART00000057422
pacsin1a
protein kinase C and casein kinase substrate in neurons 1a
chr13_-_37102522 0.58 ENSDART00000147884
syne2b
spectrin repeat containing, nuclear envelope 2b
chr21_-_40835069 0.58 ENSDART00000004686
limk1b
LIM domain kinase 1b
chr21_-_12119711 0.57 ENSDART00000131538
celf4
CUGBP, Elav-like family member 4
chr2_+_25278107 0.57 ENSDART00000131977
ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr20_+_43942278 0.57 ENSDART00000100571
clic5b
chloride intracellular channel 5b
chr15_-_20233105 0.57 ENSDART00000123910
ppp1r14ab
protein phosphatase 1, regulatory (inhibitor) subunit 14Ab
chr1_-_35916247 0.56 ENSDART00000181541
smad1
SMAD family member 1
chr11_-_277599 0.56 ENSDART00000187109
npffl
neuropeptide FF-amide peptide precursor like
chr21_+_19648814 0.56 ENSDART00000048581
fgf10a
fibroblast growth factor 10a
chr16_-_29437373 0.56 ENSDART00000148405
si:ch211-113g11.6
si:ch211-113g11.6
chr6_+_18142623 0.56 ENSDART00000169431
ENSDART00000158841
si:dkey-237i9.8
si:dkey-237i9.8
chr12_+_17100021 0.56 ENSDART00000177923
acta2
actin, alpha 2, smooth muscle, aorta
chr15_-_12229874 0.55 ENSDART00000165159
dscaml1
Down syndrome cell adhesion molecule like 1
chr20_+_320415 0.55 ENSDART00000152344
si:dkey-119m7.8
si:dkey-119m7.8
chr15_-_18176694 0.55 ENSDART00000189840
tmprss5
transmembrane protease, serine 5
chr8_+_52642869 0.55 ENSDART00000163617
ENSDART00000189997
si:dkey-90l8.3
si:dkey-90l8.3
chr20_+_2240278 0.54 ENSDART00000041250
tmem200a
transmembrane protein 200A
chr8_+_6967108 0.54 ENSDART00000004588
asic1a
acid-sensing (proton-gated) ion channel 1a
chr13_+_38302665 0.54 ENSDART00000145777
adgrb3
adhesion G protein-coupled receptor B3
chr15_+_1796313 0.54 ENSDART00000126253
fam124b
family with sequence similarity 124B
chr25_+_10830269 0.53 ENSDART00000175736
si:ch211-147g22.5
si:ch211-147g22.5
chr23_-_24582606 0.52 ENSDART00000129910
tmem240a
transmembrane protein 240a
chr2_-_32501501 0.52 ENSDART00000181309
faim2a
Fas apoptotic inhibitory molecule 2a
chr9_-_11549379 0.52 ENSDART00000187074
fev
FEV (ETS oncogene family)
chr6_+_48618512 0.51 ENSDART00000111190
FAM19A3
si:dkey-238f9.1
chr15_-_8517376 0.51 ENSDART00000186289
npas1
neuronal PAS domain protein 1
chr17_-_48705993 0.51 ENSDART00000030934
kcnk5a
potassium channel, subfamily K, member 5a
chr21_+_15824182 0.51 ENSDART00000065779
gnrh2
gonadotropin-releasing hormone 2
chr23_-_18287618 0.51 ENSDART00000112735
fam19a1a
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1a
chr1_-_206208 0.50 ENSDART00000060968
adprhl1
ADP-ribosylhydrolase like 1
chr7_+_36898622 0.50 ENSDART00000190773
tox3
TOX high mobility group box family member 3
chr7_+_57866292 0.50 ENSDART00000138757
camk2d1
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1
chr9_-_21067673 0.50 ENSDART00000180257
tbx15
T-box 15
chr5_-_41841892 0.49 ENSDART00000167089
si:dkey-65b12.6
si:dkey-65b12.6

Network of associatons between targets according to the STRING database.

First level regulatory network of ikzf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.7 2.0 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.6 2.4 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.6 2.4 GO:0061549 sympathetic ganglion development(GO:0061549)
0.5 3.3 GO:0006172 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.4 2.3 GO:0035176 mammillary body development(GO:0021767) social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.4 1.9 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.4 1.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.3 1.4 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.3 1.5 GO:0036371 protein localization to T-tubule(GO:0036371)
0.3 0.8 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.2 1.2 GO:0003210 cardiac atrium formation(GO:0003210)
0.2 2.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.2 1.8 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.2 0.8 GO:0030091 protein repair(GO:0030091)
0.2 0.6 GO:0090131 mesenchyme migration(GO:0090131)
0.2 0.9 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.2 0.9 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 1.2 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.2 0.7 GO:0048241 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.2 0.5 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.2 0.7 GO:2000583 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.2 0.8 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.2 0.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2 1.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 1.7 GO:0061615 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 1.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.6 GO:0060437 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.1 1.2 GO:0032048 cardiolipin metabolic process(GO:0032048) phosphatidylglycerol metabolic process(GO:0046471)
0.1 0.5 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.7 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 3.5 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 1.9 GO:0051764 actin crosslink formation(GO:0051764)
0.1 1.0 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.9 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.9 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.3 GO:0018315 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.3 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.1 0.3 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 2.2 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 0.3 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.1 0.2 GO:0014014 negative regulation of gliogenesis(GO:0014014)
0.1 0.4 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.2 GO:0015695 organic cation transport(GO:0015695)
0.1 0.5 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.4 GO:0055014 outflow tract morphogenesis(GO:0003151) atrial cardiac muscle cell development(GO:0055014)
0.1 0.7 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 1.3 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 0.4 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.1 0.2 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 3.9 GO:0006096 glycolytic process(GO:0006096)
0.1 0.9 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.2 GO:0090113 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.1 0.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.9 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.2 GO:0014909 smooth muscle cell migration(GO:0014909)
0.1 0.3 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.1 1.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.8 GO:0098953 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 0.1 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.6 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.6 GO:0042572 retinol metabolic process(GO:0042572)
0.0 1.1 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.4 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.4 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.4 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
0.0 0.3 GO:1900024 regulation of substrate adhesion-dependent cell spreading(GO:1900024) positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.1 GO:0003403 optic vesicle formation(GO:0003403)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.9 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.2 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.9 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.9 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:1901021 activation of store-operated calcium channel activity(GO:0032237) positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of store-operated calcium channel activity(GO:1901341) positive regulation of calcium ion transmembrane transport(GO:1904427)
0.0 0.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.7 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.0 0.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 1.4 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.3 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.4 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.7 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.8 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 0.2 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 1.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.2 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.8 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.4 GO:0009409 response to cold(GO:0009409)
0.0 0.6 GO:0007416 synapse assembly(GO:0007416)
0.0 0.9 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.8 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.6 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.5 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.2 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.3 GO:0003416 endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.4 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.2 GO:0050795 regulation of behavior(GO:0050795)
0.0 1.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.4 GO:0007596 blood coagulation(GO:0007596)
0.0 1.5 GO:0045665 negative regulation of neuron differentiation(GO:0045665)
0.0 1.1 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.1 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498) negative regulation of response to endoplasmic reticulum stress(GO:1903573) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.3 GO:0035924 cellular response to vascular endothelial growth factor stimulus(GO:0035924)
0.0 0.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.3 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0034605 cellular response to heat(GO:0034605) positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.4 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.2 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.3 GO:1990798 pancreas regeneration(GO:1990798)
0.0 2.5 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742)
0.0 0.2 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.6 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 1.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.4 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.4 GO:0071711 basement membrane organization(GO:0071711)
0.0 1.6 GO:0008284 positive regulation of cell proliferation(GO:0008284)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0044216 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.2 1.7 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.5 GO:0016460 myosin II complex(GO:0016460)
0.1 1.2 GO:0005922 connexon complex(GO:0005922)
0.1 1.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.5 GO:0030315 T-tubule(GO:0030315)
0.1 0.6 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.5 GO:0043083 synaptic cleft(GO:0043083)
0.1 2.0 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 1.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.7 GO:0030904 retromer complex(GO:0030904)
0.1 0.9 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.3 GO:0031672 A band(GO:0031672)
0.0 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 4.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 0.6 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 1.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.6 GO:0005869 dynactin complex(GO:0005869)
0.0 5.7 GO:0030017 sarcomere(GO:0030017)
0.0 0.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 2.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.3 GO:0042383 sarcolemma(GO:0042383)
0.0 0.3 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 0.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 1.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 26.3 GO:0005615 extracellular space(GO:0005615)
0.0 0.7 GO:0043204 perikaryon(GO:0043204)
0.0 1.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.6 GO:0005882 intermediate filament(GO:0005882)
0.0 1.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0017177 glucosidase II complex(GO:0017177)
0.0 0.9 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:0005795 Golgi stack(GO:0005795)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.9 GO:0004743 pyruvate kinase activity(GO:0004743)
0.5 1.6 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.4 1.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.4 1.8 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.4 1.1 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.3 1.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.3 3.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 1.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.2 1.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 2.4 GO:0016918 retinal binding(GO:0016918)
0.2 1.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.2 0.9 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 0.9 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.2 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.2 0.8 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 0.6 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.2 2.4 GO:0019238 cyclohydrolase activity(GO:0019238)
0.2 0.5 GO:0031530 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.2 0.5 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.2 1.7 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 1.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.3 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 1.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.8 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.5 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 1.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 0.9 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.3 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 1.0 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.7 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 1.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.2 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.5 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.6 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 0.3 GO:0005521 lamin binding(GO:0005521)
0.1 0.5 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 2.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.1 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.4 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.2 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 1.6 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 1.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.2 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.7 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 4.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.6 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.4 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.1 GO:0035671 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.5 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.5 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.4 GO:0019838 growth factor binding(GO:0019838)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.9 GO:0016247 channel regulator activity(GO:0016247)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 1.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 3.9 PID ALK1 PATHWAY ALK1 signaling events
0.1 1.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 2.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 0.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 3.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 1.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 1.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 3.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 3.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 1.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.7 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 0.6 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.7 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 0.5 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 2.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.1 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.1 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis