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PRJNA195909:zebrafish embryo and larva development

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Results for irf10+irf8+irf9

Z-value: 1.38

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Transcription factors associated with irf10+irf8+irf9

Gene Symbol Gene ID Gene Info
irf9
ENSDARG00000016457 interferon regulatory factor 9
irf10
ENSDARG00000027658 interferon regulatory factor 10
irf8
ENSDARG00000056407 interferon regulatory factor 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
irf8dr11_v1_chr18_+_30567945_30567945-0.835.5e-03Click!
irf9dr11_v1_chr12_+_13282797_13282807-0.636.9e-02Click!
irf10dr11_v1_chr23_+_642395_6423950.098.2e-01Click!

Activity profile of irf10+irf8+irf9 motif

Sorted Z-values of irf10+irf8+irf9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_43625549 1.97 ENSDART00000168589
ctsc
cathepsin C
chr9_-_35633827 1.78 ENSDART00000077745
zp2l1
zona pellucida glycoprotein 2, like 1
chr22_+_25274712 1.53 ENSDART00000137341
BX950205.1

chr22_+_25289360 1.38 ENSDART00000143782
si:ch211-154a22.8
si:ch211-154a22.8
chr23_+_43668756 1.32 ENSDART00000112598
otud4
OTU deubiquitinase 4
chr16_+_29509133 1.25 ENSDART00000112116
ctss2.1
cathepsin S, ortholog2, tandem duplicate 1
chr11_-_19775182 1.21 ENSDART00000037894
namptb
nicotinamide phosphoribosyltransferase b
chr23_-_29357764 1.15 ENSDART00000156512
si:ch211-129o18.4
si:ch211-129o18.4
chr14_-_45967712 1.04 ENSDART00000043751
ENSDART00000141357
macrod1
MACRO domain containing 1
chr2_+_41926707 0.99 ENSDART00000023208
zgc:110183
zgc:110183
chr4_+_279669 0.94 ENSDART00000184884
CABZ01085275.1

chr13_-_37631092 0.93 ENSDART00000108855
si:dkey-188i13.7
si:dkey-188i13.7
chr9_+_41459759 0.93 ENSDART00000132501
ENSDART00000100265
nemp2
nuclear envelope integral membrane protein 2
chr14_-_45967981 0.91 ENSDART00000188062
macrod1
MACRO domain containing 1
chr13_-_37608441 0.88 ENSDART00000140230
zgc:123068
zgc:123068
chr2_+_16585549 0.85 ENSDART00000134135
si:dkeyp-13a3.10
si:dkeyp-13a3.10
chr3_+_36127287 0.83 ENSDART00000058605
ENSDART00000182500
scpep1
serine carboxypeptidase 1
chr8_+_47188154 0.81 ENSDART00000137319
si:dkeyp-100a1.6
si:dkeyp-100a1.6
chr10_+_35152928 0.81 ENSDART00000063418
nsun5
NOP2/Sun domain family, member 5
chr7_+_22792895 0.81 ENSDART00000184407
rbm4.3
RNA binding motif protein 4.3
chr13_+_28495419 0.78 ENSDART00000025583
fgf8a
fibroblast growth factor 8a
chr15_-_24588649 0.76 ENSDART00000060469
gemin4
gem (nuclear organelle) associated protein 4
chr7_+_17908235 0.76 ENSDART00000077113
mta2
metastasis associated 1 family, member 2
chr18_+_13248956 0.75 ENSDART00000080709
plcg2
phospholipase C, gamma 2
chr15_+_24572926 0.75 ENSDART00000155636
ENSDART00000187800
dhrs13b
dehydrogenase/reductase (SDR family) member 13b
chr12_-_290413 0.74 ENSDART00000152496
adprm
ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
chr5_-_64103863 0.73 ENSDART00000135014
ENSDART00000083684
pappab
pregnancy-associated plasma protein A, pappalysin 1b
chr18_-_38270596 0.66 ENSDART00000098889
caprin1b
cell cycle associated protein 1b
chr12_-_290782 0.65 ENSDART00000152527
ENSDART00000105694
adprm
ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
chr19_+_7115223 0.64 ENSDART00000001359
psmb12
proteasome subunit beta 12
chr18_-_38270077 0.63 ENSDART00000185546
caprin1b
cell cycle associated protein 1b
chr1_-_55750208 0.63 ENSDART00000142244
dnajb1b
DnaJ (Hsp40) homolog, subfamily B, member 1b
chr16_+_29514473 0.63 ENSDART00000034102
ctss2.2
cathepsin S, ortholog 2, tandem duplicate 2
chr14_-_16810401 0.63 ENSDART00000158396
ENSDART00000170758
tcirg1b
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr6_-_32834385 0.58 ENSDART00000129803
zc3h3
zinc finger CCCH-type containing 3
chr1_-_25177086 0.58 ENSDART00000144711
ENSDART00000177225
tmem154
transmembrane protein 154
chr20_+_2739804 0.57 ENSDART00000152655
syncrip
synaptotagmin binding, cytoplasmic RNA interacting protein
chr8_-_50525360 0.57 ENSDART00000175648
CABZ01060030.1

chr21_+_45758498 0.56 ENSDART00000162548
h2afy
H2A histone family, member Y
chr4_-_17669881 0.56 ENSDART00000066997
dram1
DNA-damage regulated autophagy modulator 1
chr15_-_29162193 0.55 ENSDART00000138449
ENSDART00000099885
xaf1
XIAP associated factor 1
chr24_+_12945803 0.55 ENSDART00000005105
psme1
proteasome activator subunit 1
chr19_+_42336523 0.55 ENSDART00000151304
anp32e
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr15_-_43995028 0.55 ENSDART00000172485
ENSDART00000186320
nlrc3l
NLR family, CARD domain containing 3-like
chr5_+_13373593 0.55 ENSDART00000051668
ENSDART00000183883
ccl19a.2
chemokine (C-C motif) ligand 19a, tandem duplicate 2
chr15_-_16384184 0.55 ENSDART00000154504
fam222bb
family with sequence similarity 222, member Bb
chr21_+_20901505 0.53 ENSDART00000132741
c7b
complement component 7b
chr19_+_27448625 0.53 ENSDART00000052352
ppp1r11
protein phosphatase 1, regulatory (inhibitor) subunit 11
chr17_+_25432449 0.53 ENSDART00000150195
srrm1
serine/arginine repetitive matrix 1
chr18_-_38270430 0.52 ENSDART00000139519
caprin1b
cell cycle associated protein 1b
chr3_-_36127234 0.52 ENSDART00000130917
coil
coilin p80
chr18_-_12270845 0.52 ENSDART00000143923
ENSDART00000125555
ENSDART00000062360
ENSDART00000062216
nup205
nucleoporin 205
chr5_+_28497956 0.51 ENSDART00000191935
nfr
notochord formation related
chr22_-_17459587 0.51 ENSDART00000142267
si:ch211-197g15.10
si:ch211-197g15.10
chr7_+_40081630 0.50 ENSDART00000173559
zgc:112356
zgc:112356
chr10_-_42147318 0.49 ENSDART00000134890
dusp11
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
chr7_-_804515 0.49 ENSDART00000159359
rela
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr19_+_43878049 0.47 ENSDART00000165261
pithd1
PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
chr16_+_25285998 0.47 ENSDART00000154112
si:dkey-29h14.10
si:dkey-29h14.10
chr17_-_35076730 0.47 ENSDART00000146590
mboat2a
membrane bound O-acyltransferase domain containing 2a
chr22_+_17828267 0.47 ENSDART00000136016
hapln4
hyaluronan and proteoglycan link protein 4
chr5_-_39171302 0.47 ENSDART00000020808
paqr3a
progestin and adipoQ receptor family member IIIa
chr12_-_18578218 0.46 ENSDART00000125803
zdhhc4
zinc finger, DHHC-type containing 4
chr15_-_15227541 0.46 ENSDART00000184787
rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr22_-_37565348 0.46 ENSDART00000149482
ENSDART00000104478
fxr1
fragile X mental retardation, autosomal homolog 1
chr5_-_67661102 0.45 ENSDART00000013605
zbtb20
zinc finger and BTB domain containing 20
chr2_+_20868286 0.45 ENSDART00000062591
odr4
odr-4 GPCR localization factor homolog
chr12_-_18578432 0.45 ENSDART00000122858
zdhhc4
zinc finger, DHHC-type containing 4
chr15_-_5624361 0.44 ENSDART00000176446
ENSDART00000114410
wdr62
WD repeat domain 62
chr19_+_7597936 0.44 ENSDART00000142955
s100s
S100 calcium binding protein S
chr22_+_2512154 0.44 ENSDART00000097363
zgc:173726
zgc:173726
chr15_+_14378829 0.44 ENSDART00000160145
si:ch211-11n16.2
si:ch211-11n16.2
chr15_-_17071328 0.43 ENSDART00000122617
si:ch211-24o10.6
si:ch211-24o10.6
chr15_-_37867995 0.43 ENSDART00000192698
si:dkey-238d18.4
si:dkey-238d18.4
chr12_-_13905307 0.42 ENSDART00000152400
dbf4b
DBF4 zinc finger B
chr14_-_25078569 0.42 ENSDART00000172802
ENSDART00000173345
ENSDART00000135004
matr3l1.1
matrin 3-like 1.1
chr5_+_38662125 0.42 ENSDART00000136949
si:dkey-58f10.13
si:dkey-58f10.13
chr5_+_36895860 0.41 ENSDART00000134493
srsf7a
serine/arginine-rich splicing factor 7a
chr4_-_16658514 0.41 ENSDART00000133837
dennd5b
DENN/MADD domain containing 5B
chr8_+_26879358 0.41 ENSDART00000132485
rimkla
ribosomal modification protein rimK-like family member A
chr3_-_1938588 0.40 ENSDART00000013001
ENSDART00000186405
zgc:152753
zgc:152753
chr5_-_24869213 0.40 ENSDART00000112287
ENSDART00000144635
gas2l1
growth arrest-specific 2 like 1
chr19_-_7033636 0.40 ENSDART00000122815
ENSDART00000123443
ENSDART00000124094
daxx
death-domain associated protein
chr20_+_2739531 0.39 ENSDART00000152269
syncrip
synaptotagmin binding, cytoplasmic RNA interacting protein
chr6_+_38896158 0.39 ENSDART00000029930
ENSDART00000131347
slc48a1b
solute carrier family 48 (heme transporter), member 1b
chr18_+_19990412 0.39 ENSDART00000155054
ENSDART00000090310
pias1b
protein inhibitor of activated STAT, 1b
chr3_-_6759534 0.39 ENSDART00000180862
mast1b
microtubule associated serine/threonine kinase 1b
chr21_+_5192016 0.39 ENSDART00000139288
si:dkey-121h17.7
si:dkey-121h17.7
chr25_-_6420800 0.38 ENSDART00000153768
ptpn9a
protein tyrosine phosphatase, non-receptor type 9, a
chr11_-_20096018 0.38 ENSDART00000030420
ogfrl2
opioid growth factor receptor-like 2
chr9_+_23765587 0.38 ENSDART00000145120
si:ch211-219a4.3
si:ch211-219a4.3
chr5_-_26247215 0.38 ENSDART00000136806
erap1b
endoplasmic reticulum aminopeptidase 1b
chr5_+_32845759 0.37 ENSDART00000136552
si:ch211-208h16.4
si:ch211-208h16.4
chr15_+_20352123 0.37 ENSDART00000011030
ENSDART00000163532
ENSDART00000169537
ENSDART00000161047
il15l
interleukin 15, like
chr1_-_21563040 0.36 ENSDART00000049572
ncapd3
non-SMC condensin II complex, subunit D3
chr8_-_25422186 0.35 ENSDART00000113492
ENSDART00000131736
kcnq2a
potassium voltage-gated channel, KQT-like subfamily, member 2a
chr4_-_12795030 0.34 ENSDART00000150427
b2m
beta-2-microglobulin
chr2_-_37744951 0.34 ENSDART00000144807
myo9b
myosin IXb
chr10_+_7719796 0.34 ENSDART00000191795
ggcx
gamma-glutamyl carboxylase
chr15_+_24588963 0.34 ENSDART00000155075
zgc:198241
zgc:198241
chr11_+_1584747 0.34 ENSDART00000154583
si:dkey-40c23.2
si:dkey-40c23.2
chr25_+_35942867 0.33 ENSDART00000066985
hsd17b2
hydroxysteroid (17-beta) dehydrogenase 2
chr23_+_2666944 0.33 ENSDART00000192861
CABZ01057928.1

chr16_+_26439939 0.33 ENSDART00000143073
trim35-28
tripartite motif containing 35-28
chr5_+_45895613 0.32 ENSDART00000083937
polk
polymerase (DNA directed) kappa
chr18_+_26422124 0.32 ENSDART00000060245
ctsh
cathepsin H
chr5_-_45958838 0.31 ENSDART00000135072
poc5
POC5 centriolar protein homolog (Chlamydomonas)
chr22_-_10570749 0.30 ENSDART00000140736
si:dkey-42i9.6
si:dkey-42i9.6
chr1_-_44928987 0.30 ENSDART00000134635
si:dkey-9i23.15
si:dkey-9i23.15
chr6_-_52234796 0.30 ENSDART00000001803
tomm34
translocase of outer mitochondrial membrane 34
chr19_-_27448606 0.30 ENSDART00000079251
vars2
valyl-tRNA synthetase 2, mitochondrial (putative)
chr23_-_27692717 0.30 ENSDART00000053878
ENSDART00000145028
IKZF4
si:dkey-166n8.9
chr22_-_5958066 0.29 ENSDART00000145821
si:rp71-36a1.3
si:rp71-36a1.3
chr12_+_14149686 0.29 ENSDART00000123741
kbtbd2
kelch repeat and BTB (POZ) domain containing 2
chr2_-_38363017 0.29 ENSDART00000088026
prmt5
protein arginine methyltransferase 5
chr9_-_23765480 0.29 ENSDART00000027212
si:ch211-219a4.6
si:ch211-219a4.6
chr4_-_76383223 0.28 ENSDART00000161866
ENSDART00000168456
ENSDART00000174287
ENSDART00000174048
zgc:123107
zgc:123107
chr8_-_11202378 0.28 ENSDART00000147817
ENSDART00000174039
fam208b
family with sequence similarity 208, member B
chr5_+_36611128 0.28 ENSDART00000097684
nova1
neuro-oncological ventral antigen 1
chr4_+_40329524 0.28 ENSDART00000165722
znf993
zinc finger protein 993
chr5_-_57723929 0.27 ENSDART00000144237
gig2p
grass carp reovirus (GCRV)-induced gene 2p
chr23_+_24955394 0.27 ENSDART00000142124
nol9
nucleolar protein 9
chr14_+_21754521 0.27 ENSDART00000111839
kdm2ab
lysine (K)-specific demethylase 2Ab
chr15_-_1484795 0.27 ENSDART00000129356
si:dkeyp-97b10.3
si:dkeyp-97b10.3
chr22_-_6941098 0.27 ENSDART00000105864
zgc:171500
zgc:171500
chr16_-_5115993 0.26 ENSDART00000138654
ttk
ttk protein kinase
chr19_+_4066449 0.26 ENSDART00000162461
btr26
bloodthirsty-related gene family, member 26
chr20_-_20402500 0.26 ENSDART00000190747
ENSDART00000185065
prkchb
protein kinase C, eta, b
chr21_-_30994577 0.25 ENSDART00000065503
pgap2
post-GPI attachment to proteins 2
chr3_+_40164129 0.25 ENSDART00000102526
gfer
growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)
chr4_-_41269844 0.25 ENSDART00000186177
CR388165.2

chr13_-_25548733 0.24 ENSDART00000168099
ENSDART00000135788
ENSDART00000077655
mcmbp
minichromosome maintenance complex binding protein
chr18_+_34667486 0.24 ENSDART00000163583
CR626874.1

chr6_+_32834760 0.24 ENSDART00000121562
cyldl
cylindromatosis (turban tumor syndrome), like
chr5_-_30382925 0.23 ENSDART00000125381
gig2o
grass carp reovirus (GCRV)-induced gene 2o
chr22_-_7461603 0.23 ENSDART00000170630
BX511034.6

chr18_-_12858016 0.23 ENSDART00000130343
parp12a
poly (ADP-ribose) polymerase family, member 12a
chr7_-_29043075 0.23 ENSDART00000052342
thap11
THAP domain containing 11
chr15_-_17169935 0.23 ENSDART00000110111
cul5a
cullin 5a
chr5_+_45895791 0.22 ENSDART00000141039
polk
polymerase (DNA directed) kappa
chr3_+_938438 0.22 ENSDART00000165671
irgf4
immunity-related GTPase family, f4
chr14_+_31566517 0.22 ENSDART00000002684
ints6l
integrator complex subunit 6 like
chr16_-_25285469 0.21 ENSDART00000183943
ENSDART00000191103
ENSDART00000154543
prelid3a
PRELI domain containing 3A
chr22_-_8174244 0.21 ENSDART00000156571
si:ch73-44m9.3
si:ch73-44m9.3
chr8_+_1187928 0.21 ENSDART00000127252
slc35d2
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr16_+_26439518 0.21 ENSDART00000041787
trim35-28
tripartite motif containing 35-28
chr23_-_31974060 0.20 ENSDART00000168087
BX927210.1

chr21_+_17542473 0.20 ENSDART00000005750
ENSDART00000141326
stom
stomatin
chr10_+_7255695 0.20 ENSDART00000161506
ENSDART00000181304
fut10
fucosyltransferase 10
chr15_+_2421729 0.20 ENSDART00000082294
ENSDART00000156428
hephl1a
hephaestin-like 1a
chr6_-_52235118 0.20 ENSDART00000191243
tomm34
translocase of outer mitochondrial membrane 34
chr3_+_24603923 0.19 ENSDART00000172589
si:dkey-68o6.6
si:dkey-68o6.6
chr8_+_22277198 0.19 ENSDART00000005989
dffb
DNA fragmentation factor, beta polypeptide (caspase-activated DNase)
chr22_-_17474583 0.18 ENSDART00000148027
si:ch211-197g15.8
si:ch211-197g15.8
chr12_-_19151708 0.18 ENSDART00000057124
tefa
thyrotrophic embryonic factor a
chr21_-_22648007 0.18 ENSDART00000121788
gig2l
grass carp reovirus (GCRV)-induced gene 2l
chr12_-_26559650 0.18 ENSDART00000153401
tap2t
transporter associated with antigen processing, subunit type t, teleost specific
chr12_-_35936329 0.18 ENSDART00000166634
rnf213b
ring finger protein 213b
chr2_-_40889465 0.18 ENSDART00000192631
ENSDART00000180824
uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr25_+_32390794 0.18 ENSDART00000012600
galk2
galactokinase 2
chr22_+_1589407 0.17 ENSDART00000175704
si:ch211-255f4.11
si:ch211-255f4.11
chr3_+_52999962 0.17 ENSDART00000104683
pbx4
pre-B-cell leukemia transcription factor 4
chr19_+_22085925 0.17 ENSDART00000185636
atp9b
ATPase phospholipid transporting 9B
chr10_+_26645953 0.16 ENSDART00000131482
adgrg4b
adhesion G protein-coupled receptor G4b
chr3_-_52661242 0.16 ENSDART00000138018
zgc:113210
zgc:113210
chr23_+_29357790 0.16 ENSDART00000139223
ENSDART00000141928
tardbpl
TAR DNA binding protein, like
chr10_+_31809226 0.16 ENSDART00000087898
foxo1b
forkhead box O1 b
chr7_-_52417060 0.16 ENSDART00000148579
myzap
myocardial zonula adherens protein
chr11_-_31276064 0.16 ENSDART00000141062
ENSDART00000004780
man2b1
mannosidase, alpha, class 2B, member 1
chr22_+_8979955 0.16 ENSDART00000144005
si:ch211-213a13.1
si:ch211-213a13.1
chr3_-_44753325 0.15 ENSDART00000074543
hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr19_+_7124337 0.15 ENSDART00000031380
tap2a
transporter associated with antigen processing, subunit type a
chr4_-_26095755 0.15 ENSDART00000100611
ENSDART00000191266
si:ch211-244b2.3
si:ch211-244b2.3
chr25_-_27665978 0.15 ENSDART00000123590
si:ch211-91p5.3
si:ch211-91p5.3
chr7_+_56651759 0.15 ENSDART00000073600
kcng4b
potassium voltage-gated channel, subfamily G, member 4b
chr14_-_26465729 0.14 ENSDART00000143454
syvn1
synovial apoptosis inhibitor 1, synoviolin
chr16_-_11986321 0.14 ENSDART00000148666
ENSDART00000029121
usp5
ubiquitin specific peptidase 5 (isopeptidase T)
chr4_-_58945951 0.14 ENSDART00000159145
si:dkey-28i19.4
si:dkey-28i19.4
chr3_-_4455951 0.14 ENSDART00000193908
ENSDART00000074077
trim35-3
tripartite motif containing 35-3
chr1_+_38858399 0.14 ENSDART00000165454
CU915762.1

chr6_+_52947699 0.14 ENSDART00000180913
uba7
ubiquitin-like modifier activating enzyme 7
chr21_-_40557281 0.14 ENSDART00000172327
taok1b
TAO kinase 1b
chr22_+_2459591 0.14 ENSDART00000182602
si:ch73-92e7.4
si:ch73-92e7.4
chr25_-_35524166 0.13 ENSDART00000156782
slc5a12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr1_-_50710468 0.13 ENSDART00000080389
fam13a
family with sequence similarity 13, member A
chr13_-_37642890 0.13 ENSDART00000146483
ENSDART00000136071
ENSDART00000111786
si:dkey-188i13.9
si:dkey-188i13.9
chr3_-_45361573 0.13 ENSDART00000154796
il21r.1
interleukin 21 receptor, tandem duplicate 1
chr6_+_32834007 0.13 ENSDART00000157353
cyldl
cylindromatosis (turban tumor syndrome), like
chr3_-_12026741 0.13 ENSDART00000132238
cfap70
cilia and flagella associated protein 70
chr15_-_15965456 0.13 ENSDART00000154579
synrg
synergin, gamma
chr6_-_43270160 0.12 ENSDART00000180990
frmd4ba
FERM domain containing 4Ba
chr4_+_35198656 0.12 ENSDART00000187990
si:dkey-269p2.1
si:dkey-269p2.1
chr1_-_7951002 0.12 ENSDART00000138187
si:dkey-79f11.8
si:dkey-79f11.8
chr13_+_7578111 0.12 ENSDART00000175431
gbf1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr22_+_1541083 0.12 ENSDART00000169338
si:ch211-255f4.7
si:ch211-255f4.7
chr3_-_7997887 0.12 ENSDART00000172256
TRIM35 (1 of many)
si:ch211-175l6.2
chr2_-_32688905 0.12 ENSDART00000041146
nrbp2a
nuclear receptor binding protein 2a
chr3_-_32079916 0.11 ENSDART00000040900
baxb
BCL2 associated X, apoptosis regulator b
chr22_-_17474781 0.11 ENSDART00000186817
si:ch211-197g15.8
si:ch211-197g15.8
chr4_-_75616197 0.11 ENSDART00000157778
si:dkey-71l4.3
si:dkey-71l4.3

Network of associatons between targets according to the STRING database.

First level regulatory network of irf10+irf8+irf9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.8 GO:0061193 rhombomere 5 development(GO:0021571) rhombomere 6 development(GO:0021572) tongue development(GO:0043586) tongue morphogenesis(GO:0043587) taste bud development(GO:0061193) taste bud morphogenesis(GO:0061194) taste bud formation(GO:0061195)
0.1 1.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.5 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.1 0.5 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.1 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.3 GO:1902102 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.1 0.8 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.5 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.3 GO:0034969 histone arginine methylation(GO:0034969)
0.1 0.3 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.5 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.3 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.1 0.4 GO:2000105 positive regulation of DNA-dependent DNA replication(GO:2000105)
0.1 0.3 GO:0014005 microglia development(GO:0014005)
0.1 0.3 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0055057 neuroblast division(GO:0055057)
0.0 0.3 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.6 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.5 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.4 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 0.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.3 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.2 GO:0003232 bulbus arteriosus development(GO:0003232) negative regulation of histone methylation(GO:0031061)
0.0 0.4 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.2 GO:0030262 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.2 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.9 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.5 GO:0043486 histone exchange(GO:0043486)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.6 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.5 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0031179 peptide modification(GO:0031179)
0.0 0.1 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.0 0.5 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.7 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 1.7 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.4 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.5 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 0.5 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.2 GO:0036065 fucosylation(GO:0036065)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.8 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.4 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.1 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.5 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.5 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.1 1.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.8 GO:0032797 SMN complex(GO:0032797)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.5 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.8 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0042611 MHC protein complex(GO:0042611) MHC class II protein complex(GO:0042613)
0.0 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.5 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 5.1 GO:0005764 lysosome(GO:0005764)
0.0 1.6 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.4 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.4 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.1 1.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.5 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 1.4 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.5 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.1 0.8 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.3 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.1 0.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.3 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.1 0.2 GO:0046978 TAP1 binding(GO:0046978)
0.1 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.2 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.0 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.6 GO:0051117 ATPase binding(GO:0051117)
0.0 0.2 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.7 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.9 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 2.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.5 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.5 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.5 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.7 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 1.6 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.5 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 1.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis