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PRJNA195909:zebrafish embryo and larva development

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Results for isl2a+isl2b

Z-value: 0.90

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Transcription factors associated with isl2a+isl2b

Gene Symbol Gene ID Gene Info
isl2a
ENSDARG00000003971 ISL LIM homeobox 2a
isl2b
ENSDARG00000053499 ISL LIM homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
isl2adr11_v1_chr25_-_32751982_327519820.863.3e-03Click!
isl2bdr11_v1_chr7_+_29992889_299928890.723.0e-02Click!

Activity profile of isl2a+isl2b motif

Sorted Z-values of isl2a+isl2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_15433518 4.25 ENSDART00000026180
fabp7a
fatty acid binding protein 7, brain, a
chr17_+_15433671 4.02 ENSDART00000149568
fabp7a
fatty acid binding protein 7, brain, a
chr7_+_39166460 2.78 ENSDART00000052318
ENSDART00000146635
ENSDART00000173877
ENSDART00000173767
ENSDART00000173600
mdka
midkine a
chr3_+_28939759 2.39 ENSDART00000141904
lgals1l1
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
chr5_-_41494831 2.02 ENSDART00000051081
eef2l2
eukaryotic translation elongation factor 2, like 2
chr25_+_21833287 1.94 ENSDART00000187606
ckmt1
creatine kinase, mitochondrial 1
chr7_+_22657566 1.68 ENSDART00000141048
ponzr5
plac8 onzin related protein 5
chr8_-_50147948 1.53 ENSDART00000149010
hp
haptoglobin
chr15_-_2640966 1.44 ENSDART00000063320
cldne
claudin e
chr18_+_30847237 1.37 ENSDART00000012374
foxf1
forkhead box F1
chr7_-_48665305 1.35 ENSDART00000190507
cdkn1ca
cyclin-dependent kinase inhibitor 1Ca
chr15_+_36115955 1.30 ENSDART00000032702
sst1.2
somatostatin 1, tandem duplicate 2
chr24_-_26310854 1.21 ENSDART00000080113
apodb
apolipoprotein Db
chr13_-_36391496 1.16 ENSDART00000100217
ENSDART00000140243
actn1
actinin, alpha 1
chr3_-_19368435 1.14 ENSDART00000132987
s1pr5a
sphingosine-1-phosphate receptor 5a
chr15_+_46356879 1.11 ENSDART00000154388
wu:fb18f06
wu:fb18f06
chr17_-_29224908 1.06 ENSDART00000156288
si:dkey-28g23.6
si:dkey-28g23.6
chr16_-_21140097 1.06 ENSDART00000145837
ENSDART00000146500
si:dkey-271j15.3
si:dkey-271j15.3
chr13_-_2010191 1.01 ENSDART00000161021
ENSDART00000124134
gfral
GDNF family receptor alpha like
chr11_-_1400507 0.99 ENSDART00000173029
ENSDART00000172953
ENSDART00000111140
rpl29
ribosomal protein L29
chr17_-_14815557 0.99 ENSDART00000154473
nid2a
nidogen 2a (osteonidogen)
chr5_+_58550291 0.96 ENSDART00000184983
ENSDART00000044803
pou2f3
POU class 2 homeobox 3
chr1_-_42289704 0.95 ENSDART00000150124
si:ch211-71k14.1
si:ch211-71k14.1
chr21_-_37194839 0.94 ENSDART00000175126
fgfr4
fibroblast growth factor receptor 4
chr12_-_4781801 0.94 ENSDART00000167490
ENSDART00000121718
mapta
microtubule-associated protein tau a
chr16_+_28728347 0.92 ENSDART00000149240
si:dkey-24i24.3
si:dkey-24i24.3
chr14_-_24391424 0.91 ENSDART00000113376
ENSDART00000126894
fam13b
family with sequence similarity 13, member B
chr7_+_26534131 0.90 ENSDART00000173980
si:dkey-62k3.5
si:dkey-62k3.5
chr10_-_43771447 0.90 ENSDART00000052307
arrdc3b
arrestin domain containing 3b
chr11_-_45138857 0.88 ENSDART00000166501
cant1b
calcium activated nucleotidase 1b
chr7_+_60079302 0.88 ENSDART00000051524
etnppl
ethanolamine-phosphate phospho-lyase
chr15_-_14884332 0.87 ENSDART00000165237
si:ch211-24o8.4
si:ch211-24o8.4
chr20_+_11731039 0.87 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
si:ch211-155o21.3
chr16_-_17072440 0.85 ENSDART00000002493
ENSDART00000178443
tnfrsf1a
tumor necrosis factor receptor superfamily, member 1a
chr21_-_19314618 0.84 ENSDART00000188744
gpat3
glycerol-3-phosphate acyltransferase 3
chr5_-_31901468 0.84 ENSDART00000147814
ENSDART00000141446
coro1cb
coronin, actin binding protein, 1Cb
chr14_-_4145594 0.83 ENSDART00000077348
casp3b
caspase 3, apoptosis-related cysteine peptidase b
chr1_-_669717 0.83 ENSDART00000160564
cyyr1
cysteine/tyrosine-rich 1
chr14_-_413273 0.82 ENSDART00000163976
ENSDART00000179907
FAT4
FAT atypical cadherin 4
chr12_+_24342303 0.80 ENSDART00000111239
nrxn1a
neurexin 1a
chr6_-_49510553 0.79 ENSDART00000166238
rplp2
ribosomal protein, large P2
chr3_+_38540411 0.78 ENSDART00000154943
si:dkey-7f16.3
si:dkey-7f16.3
chr21_+_25236297 0.78 ENSDART00000112783
tmem45b
transmembrane protein 45B
chr23_-_16485190 0.77 ENSDART00000155038
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr7_+_59020972 0.77 ENSDART00000157873
hacd1
3-hydroxyacyl-CoA dehydratase 1
chr9_-_32753535 0.77 ENSDART00000060006
olig2
oligodendrocyte lineage transcription factor 2
chr24_+_13869092 0.76 ENSDART00000176492
eya1
EYA transcriptional coactivator and phosphatase 1
chr11_-_1509773 0.76 ENSDART00000050762
phactr3b
phosphatase and actin regulator 3b
chr1_-_50859053 0.74 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr4_-_9909371 0.73 ENSDART00000102656
si:dkey-22l11.6
si:dkey-22l11.6
chr20_-_5291012 0.73 ENSDART00000122892
cyp46a1.3
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
chr18_-_48547564 0.72 ENSDART00000138607
kcnj1a.1
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr24_-_6078222 0.72 ENSDART00000146830
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr6_+_52350443 0.72 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
si:ch211-239j9.1
chr8_+_24747865 0.69 ENSDART00000078656
slc16a4
solute carrier family 16, member 4
chr3_-_36839115 0.69 ENSDART00000154553
ramp2
receptor (G protein-coupled) activity modifying protein 2
chr23_-_18913032 0.68 ENSDART00000136678
si:ch211-209j10.6
si:ch211-209j10.6
chr21_+_45841731 0.68 ENSDART00000038657
faxdc2
fatty acid hydroxylase domain containing 2
chr3_+_32553714 0.66 ENSDART00000165638
pax10
paired box 10
chr23_-_36724575 0.65 ENSDART00000159560
agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr6_-_8311044 0.65 ENSDART00000129674
slc44a2
solute carrier family 44 (choline transporter), member 2
chr21_-_25522510 0.62 ENSDART00000162711
cnksr2b
connector enhancer of kinase suppressor of Ras 2b
chr1_-_25966068 0.62 ENSDART00000137869
ENSDART00000134192
synpo2b
synaptopodin 2b
chr3_+_14388010 0.61 ENSDART00000171726
ENSDART00000165452
tmem56b
transmembrane protein 56b
chr16_-_48400639 0.60 ENSDART00000159372
eif3ha
eukaryotic translation initiation factor 3, subunit H, a
chr16_+_28932038 0.60 ENSDART00000149480
npr1b
natriuretic peptide receptor 1b
chr15_+_9327252 0.59 ENSDART00000144381
sgcg
sarcoglycan, gamma
chr19_-_5769728 0.57 ENSDART00000133106
si:ch211-264f5.6
si:ch211-264f5.6
chr11_+_30057762 0.56 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr3_-_19200571 0.54 ENSDART00000131503
ENSDART00000012335
rfx1a
regulatory factor X, 1a (influences HLA class II expression)
chr14_-_7137808 0.53 ENSDART00000054803
trpt1
tRNA phosphotransferase 1
chr6_+_54538948 0.52 ENSDART00000149270
tulp1b
tubby like protein 1b
chr7_+_20512419 0.52 ENSDART00000173907
si:dkey-19b23.14
si:dkey-19b23.14
chr16_-_45094599 0.52 ENSDART00000155479
si:rp71-77l1.1
si:rp71-77l1.1
chr21_-_17482465 0.51 ENSDART00000004548
barhl1b
BarH-like homeobox 1b
chr18_-_15932704 0.50 ENSDART00000127769
plekhg7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr25_+_13406069 0.49 ENSDART00000010495
znrf1
zinc and ring finger 1
chr3_-_22216771 0.48 ENSDART00000130546
maptb
microtubule-associated protein tau b
chr9_+_24008879 0.48 ENSDART00000190419
ENSDART00000191843
ENSDART00000148226
mlphb
melanophilin b
chr8_+_23521974 0.47 ENSDART00000188130
ENSDART00000129378
sema3gb
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr22_-_23545828 0.47 ENSDART00000161253
crb1
crumbs family member 1, photoreceptor morphogenesis associated
chr3_-_25119839 0.47 ENSDART00000154724
chadla
chondroadherin-like a
chr5_-_19861766 0.46 ENSDART00000088904
gltpa
glycolipid transfer protein a
chr10_-_7756865 0.45 ENSDART00000114373
ENSDART00000125407
ENSDART00000016317
loxa
lysyl oxidase a
chr3_-_39180048 0.44 ENSDART00000049720
cdk21
cyclin-dependent kinase 21
chr13_+_23282549 0.44 ENSDART00000101134
khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr12_+_18681477 0.44 ENSDART00000127981
ENSDART00000143979
rgs9b
regulator of G protein signaling 9b
chr2_+_10771787 0.43 ENSDART00000187782
gfi1aa
growth factor independent 1A transcription repressor a
chr23_-_33350990 0.42 ENSDART00000144831
si:ch211-226m16.2
si:ch211-226m16.2
chr10_+_31248036 0.41 ENSDART00000193574
robo4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr7_-_12821277 0.41 ENSDART00000091584
zgc:158785
zgc:158785
chr23_+_9353552 0.40 ENSDART00000163298
BX511246.1

chr25_+_7671640 0.39 ENSDART00000145367
kcnj11l
potassium inwardly-rectifying channel, subfamily J, member 11, like
chr21_+_11385031 0.39 ENSDART00000040598
cel.2
carboxyl ester lipase, tandem duplicate 2
chr1_-_9641845 0.39 ENSDART00000121490
ENSDART00000159411
ugt5b2
ugt5b3
UDP glucuronosyltransferase 5 family, polypeptide B2
UDP glucuronosyltransferase 5 family, polypeptide B3
chr16_+_10972733 0.37 ENSDART00000049323
pou2f2a
POU class 2 homeobox 2a
chr24_+_16985181 0.37 ENSDART00000135580
eif2s3
eukaryotic translation initiation factor 2, subunit 3 gamma
chr13_-_42560662 0.37 ENSDART00000124898
CR792417.1

chr6_+_9175886 0.37 ENSDART00000165333
si:ch211-207l14.1
si:ch211-207l14.1
chr1_+_51721851 0.36 ENSDART00000040397
prdx2
peroxiredoxin 2
chr15_-_46779934 0.35 ENSDART00000085136
clcn2c
chloride channel 2c
chr5_-_42083363 0.35 ENSDART00000162596
cxcl11.5
chemokine (C-X-C motif) ligand 11, duplicate 5
chr12_-_28363111 0.35 ENSDART00000016283
ENSDART00000164156
psmd11b
proteasome 26S subunit, non-ATPase 11b
chr10_-_17083180 0.34 ENSDART00000170083
fam166b
family with sequence similarity 166, member B
chr22_-_12745589 0.34 ENSDART00000136841
plcd4a
phospholipase C, delta 4a
chr19_+_24872159 0.32 ENSDART00000158490
si:ch211-195b13.1
si:ch211-195b13.1
chr17_+_16564921 0.32 ENSDART00000151904
foxn3
forkhead box N3
chr23_-_16484383 0.31 ENSDART00000187839
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr22_-_19552796 0.30 ENSDART00000148088
ENSDART00000105485
si:dkey-78l4.14
si:dkey-78l4.14
chr7_-_71829649 0.30 ENSDART00000160449
cacnb2a
calcium channel, voltage-dependent, beta 2a
chr11_-_29737088 0.29 ENSDART00000159828
si:ch211-218g23.6
si:ch211-218g23.6
chr24_+_33622769 0.28 ENSDART00000079342
dnah5l
dynein, axonemal, heavy chain 5 like
chr7_-_50410524 0.28 ENSDART00000083346
hypk
huntingtin interacting protein K
chr22_-_17844117 0.27 ENSDART00000159363
BX908731.1

chr6_+_9204099 0.26 ENSDART00000150167
ENSDART00000115394
tbx19
T-box 19
chr18_+_34225520 0.26 ENSDART00000126115
v2rl1
vomeronasal 2 receptor, l1
chr15_-_14552101 0.25 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr22_-_17482810 0.25 ENSDART00000171293
si:ch211-197g15.7
si:ch211-197g15.7
chr6_+_39905021 0.25 ENSDART00000064904
endou
endonuclease, polyU-specific
chr2_+_20605925 0.25 ENSDART00000191510
olfml2bb
olfactomedin-like 2Bb
chr5_+_56023186 0.24 ENSDART00000156230
fzd9a
frizzled class receptor 9a
chr16_+_11660839 0.23 ENSDART00000193911
ENSDART00000143683
si:dkey-250k15.10
si:dkey-250k15.10
chr3_+_26342768 0.23 ENSDART00000163832
si:ch211-156b7.4
si:ch211-156b7.4
chr12_+_1139690 0.23 ENSDART00000160442
CABZ01072885.1

chr24_-_3477103 0.23 ENSDART00000143723
idi1
isopentenyl-diphosphate delta isomerase 1
chr2_+_19578446 0.23 ENSDART00000164758
pimr50
Pim proto-oncogene, serine/threonine kinase, related 50
chr8_+_25913787 0.21 ENSDART00000190257
ENSDART00000062515
sema3h
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3H
chr22_-_36530902 0.21 ENSDART00000056188
polr2h
info polymerase (RNA) II (DNA directed) polypeptide H
chr2_-_45027754 0.21 ENSDART00000168469
vwa5b2
von Willebrand factor A domain containing 5B2
chr6_+_7533601 0.21 ENSDART00000057823
pa2g4a
proliferation-associated 2G4, a
chr8_+_52637507 0.21 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr11_+_30663300 0.21 ENSDART00000161662
ttbk1a
tau tubulin kinase 1a
chr8_+_1651821 0.20 ENSDART00000060865
ENSDART00000186304
rasal1b
RAS protein activator like 1b (GAP1 like)
chr4_+_19700308 0.20 ENSDART00000027919
pax4
paired box 4
chr18_-_8398972 0.20 ENSDART00000136512
BEND7
si:ch211-220f12.4
chr10_+_34685135 0.19 ENSDART00000184999
nbeaa
neurobeachin a
chr24_-_6897884 0.19 ENSDART00000080766
dpp6a
dipeptidyl-peptidase 6a
chr12_-_34713690 0.19 ENSDART00000180807
bahcc1b
BAH domain and coiled-coil containing 1b
chr18_-_3473081 0.19 ENSDART00000174975
myo7aa
myosin VIIAa
chr10_+_29850330 0.18 ENSDART00000168898
hspa8
heat shock protein 8
chr21_-_35534401 0.18 ENSDART00000112308
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr21_-_35419486 0.18 ENSDART00000138529
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr10_-_17222083 0.18 ENSDART00000134059
depdc5
DEP domain containing 5
chr17_-_2834764 0.18 ENSDART00000024027
bdkrb1
bradykinin receptor B1
chr22_-_23545307 0.18 ENSDART00000166915
crb1
crumbs family member 1, photoreceptor morphogenesis associated
chr17_+_12285285 0.18 ENSDART00000154336
pimr174
Pim proto-oncogene, serine/threonine kinase, related 174
chr20_+_66857 0.17 ENSDART00000114999
lrfn2b
leucine rich repeat and fibronectin type III domain containing 2b
chr10_-_43404027 0.17 ENSDART00000086227
edil3b
EGF-like repeats and discoidin I-like domains 3b
chr15_+_34988148 0.17 ENSDART00000076269
ccdc105
coiled-coil domain containing 105
chr11_+_29856032 0.16 ENSDART00000079150
grpr
gastrin-releasing peptide receptor
chr25_+_35212919 0.16 ENSDART00000180127
ano5a
anoctamin 5a
chr24_+_12894282 0.15 ENSDART00000061301
si:dkeyp-28d2.4
si:dkeyp-28d2.4
chr21_-_20939488 0.15 ENSDART00000039043
rgs7bpb
regulator of G protein signaling 7 binding protein b
chr7_+_66822229 0.15 ENSDART00000112109
lyve1a
lymphatic vessel endothelial hyaluronic receptor 1a
chr2_-_19520324 0.15 ENSDART00000079877
pimr52
Pim proto-oncogene, serine/threonine kinase, related 52
chr8_-_13046089 0.14 ENSDART00000137784
si:dkey-208b23.5
si:dkey-208b23.5
chr16_+_54209504 0.14 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr24_+_12989727 0.14 ENSDART00000126842
ENSDART00000129309
flj11011l
hypothetical protein FLJ11011-like (H. sapiens)
chr20_-_47188966 0.14 ENSDART00000152965
si:dkeyp-104f11.9
si:dkeyp-104f11.9
chr3_+_3681116 0.13 ENSDART00000109618
art4
ADP-ribosyltransferase 4 (Dombrock blood group)
chr12_+_16168342 0.13 ENSDART00000079326
ENSDART00000170024
lrp2b
low density lipoprotein receptor-related protein 2b
chr12_-_4532066 0.13 ENSDART00000092687
trpm4b.2
transient receptor potential cation channel, subfamily M, member 4b, transient receptor potential cation channel, subfamily M, member 4b, tandem duplicate 2
chr20_+_40457599 0.12 ENSDART00000017553
serinc1
serine incorporator 1
chr2_-_19520690 0.12 ENSDART00000133559
pimr52
Pim proto-oncogene, serine/threonine kinase, related 52
chr4_-_17669881 0.12 ENSDART00000066997
dram1
DNA-damage regulated autophagy modulator 1
chr18_+_43891051 0.12 ENSDART00000024213
cxcr5
chemokine (C-X-C motif) receptor 5
chr19_+_16015881 0.11 ENSDART00000187135
ctps1a
CTP synthase 1a
chr9_+_32069989 0.11 ENSDART00000139540
si:dkey-83m22.7
si:dkey-83m22.7
chr25_+_30799236 0.10 ENSDART00000180181
CR753816.1

chr14_+_36521005 0.10 ENSDART00000192286
TENM3
si:dkey-237h12.3
chr20_+_36234335 0.10 ENSDART00000193484
ENSDART00000181664
cnih3
cornichon family AMPA receptor auxiliary protein 3
chr3_-_30061985 0.09 ENSDART00000189583
ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr24_+_2495197 0.09 ENSDART00000146887
f13a1a.1
coagulation factor XIII, A1 polypeptide a, tandem duplicate 1
chr8_-_53044089 0.09 ENSDART00000135982
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr13_-_12602920 0.09 ENSDART00000102311
lrit3b
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr3_+_23029934 0.07 ENSDART00000110343
nags
N-acetylglutamate synthase
chr2_+_19633493 0.07 ENSDART00000147989
pimr54
Pim proto-oncogene, serine/threonine kinase, related 54
chr2_+_19522082 0.07 ENSDART00000146098
pimr49
Pim proto-oncogene, serine/threonine kinase, related 49
chr6_-_52788213 0.07 ENSDART00000179880
rbpjl
recombination signal binding protein for immunoglobulin kappa J region-like
chr15_-_21702317 0.07 ENSDART00000155824
IL4I1
si:dkey-40g16.6
chr24_-_32173754 0.06 ENSDART00000048633
trdmt1
tRNA aspartic acid methyltransferase 1
chr22_+_19552987 0.05 ENSDART00000105315
hsd11b1la
hydroxysteroid (11-beta) dehydrogenase 1-like a
chr4_-_77218637 0.05 ENSDART00000174325
psmb10
proteasome subunit beta 10
chr9_+_1039215 0.05 ENSDART00000192186
DOCK9 (1 of many)
dedicator of cytokinesis 9
chr16_-_16761164 0.04 ENSDART00000135872
si:dkey-27n14.1
si:dkey-27n14.1
chr9_+_51147380 0.04 ENSDART00000003913
ifih1
interferon induced with helicase C domain 1
chr19_+_45962016 0.04 ENSDART00000169710
utp23
UTP23, small subunit (SSU) processome component, homolog (yeast)
chr2_-_48512450 0.04 ENSDART00000160132
CR391991.1

chr6_-_54486410 0.04 ENSDART00000064679
CR847944.1

chr19_-_5125663 0.04 ENSDART00000005547
ENSDART00000132642
gnb3b
guanine nucleotide binding protein (G protein), beta polypeptide 3b
chr23_+_32406461 0.04 ENSDART00000179878
si:ch211-66i15.5
si:ch211-66i15.5
chr3_+_23029484 0.04 ENSDART00000187900
nags
N-acetylglutamate synthase
chr12_+_10062953 0.03 ENSDART00000148689
slc4a1b
solute carrier family 4 (anion exchanger), member 1b (Diego blood group)
chr1_-_10048514 0.03 ENSDART00000125358
ENSDART00000054835
rnf175
ring finger protein 175
chr2_-_59205393 0.02 ENSDART00000056417
ENSDART00000182452
ENSDART00000141876
ftr30
finTRIM family, member 30
chr11_-_36341189 0.02 ENSDART00000159752
sort1a
sortilin 1a
chr20_+_46202188 0.01 ENSDART00000100523
taar13c
trace amine associated receptor 13c
chr14_-_2206476 0.01 ENSDART00000081870
pcdh2ab6
protocadherin 2 alpha b 6
chr20_-_23171430 0.01 ENSDART00000109234
spata18
spermatogenesis associated 18
chr10_-_40964739 0.00 ENSDART00000076359
npffr1l1
neuropeptide FF receptor 1 like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of isl2a+isl2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.3 0.8 GO:0002432 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.2 1.3 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.2 0.8 GO:0021742 abducens nucleus development(GO:0021742)
0.2 0.6 GO:0015871 choline transport(GO:0015871)
0.1 1.9 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 2.8 GO:0070654 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.1 0.4 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 0.3 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.1 0.8 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.4 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.8 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.7 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 1.2 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.4 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 0.6 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.1 0.5 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.8 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 2.8 GO:0006414 translational elongation(GO:0006414)
0.0 0.2 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.0 0.2 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.1 GO:0002369 T cell cytokine production(GO:0002369)
0.0 0.4 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 1.2 GO:0007568 aging(GO:0007568)
0.0 0.4 GO:0071450 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.8 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.2 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.0 1.4 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.4 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 1.0 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.6 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.6 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.7 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.7 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.7 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 1.0 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.5 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 2.2 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 1.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.8 GO:0030018 Z disc(GO:0030018)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.4 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.0 GO:0005604 basement membrane(GO:0005604)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.3 GO:0005504 fatty acid binding(GO:0005504)
0.2 2.4 GO:0016936 galactoside binding(GO:0016936)
0.2 0.8 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.2 0.8 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.2 1.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 0.6 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 1.9 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 1.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.4 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.7 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.1 0.8 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.9 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.7 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.1 1.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.6 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 2.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.8 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.7 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.9 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.6 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 2.8 GO:0008201 heparin binding(GO:0008201)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.5 GO:0017022 myosin binding(GO:0017022)
0.0 0.3 GO:0051020 GTPase binding(GO:0051020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.7 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.9 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 1.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 2.2 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.1 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway