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PRJNA195909:zebrafish embryo and larva development

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Results for lef1

Z-value: 2.48

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Transcription factors associated with lef1

Gene Symbol Gene ID Gene Info
ENSDARG00000031894 lymphoid enhancer-binding factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lef1dr11_v1_chr1_+_49814942_49814942-0.881.9e-03Click!

Activity profile of lef1 motif

Sorted Z-values of lef1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_23913943 6.09 ENSDART00000175404
ENSDART00000129525
apolipoprotein A-IV b, tandem duplicate 1
chr16_-_45917322 5.51 ENSDART00000060822
antifreeze protein type IV
chr16_-_45910050 5.09 ENSDART00000133213
antifreeze protein type IV
chr23_-_10175898 4.96 ENSDART00000146185
keratin 5
chr18_-_23875370 4.30 ENSDART00000130163
nuclear receptor subfamily 2, group F, member 2
chr15_-_3736149 3.89 ENSDART00000182986
lysophosphatidic acid receptor 6a
chr25_+_34576067 3.84 ENSDART00000157519
transient receptor potential cation channel, subfamily M, member 1b
chr9_-_33877476 3.77 ENSDART00000150035
ENSDART00000088441
ENSDART00000183210
si:ch73-147f11.1
chr24_-_37568359 3.77 ENSDART00000056286
H1 histone family, member 0
chr1_+_17376922 3.73 ENSDART00000145068
FAT atypical cadherin 1a
chr21_-_28920245 3.69 ENSDART00000132884
CXXC finger protein 5a
chr10_+_9550419 3.63 ENSDART00000064977
si:ch211-243g18.2
chr20_-_48485354 3.61 ENSDART00000124040
ENSDART00000148437
insulinoma-associated 1a
chr14_+_7932973 3.59 ENSDART00000109941
CXXC finger protein 5b
chr9_+_25330905 3.58 ENSDART00000101470
integral membrane protein 2Bb
chr14_-_8080416 3.53 ENSDART00000045109
zgc:92242
chr9_-_11560427 3.40 ENSDART00000127942
ENSDART00000061442
crystallin, beta A2b
chr11_-_5865744 3.20 ENSDART00000104360
guanidinoacetate N-methyltransferase
chr15_-_107900 3.17 ENSDART00000193184
apolipoprotein A-Ib
chr13_-_31441042 3.10 ENSDART00000076571
reticulon 1a
chr5_+_49744713 3.09 ENSDART00000133384
nuclear receptor subfamily 2, group F, member 1a
chr25_+_20089986 2.85 ENSDART00000143441
ENSDART00000184073
troponin I4b, tandem duplicate 2
chr19_+_19777437 2.84 ENSDART00000170662
homeobox A3a
chr9_-_7683799 2.79 ENSDART00000102713
si:ch73-199e17.1
chr16_-_45917683 2.73 ENSDART00000184289
antifreeze protein type IV
chr10_+_32104305 2.73 ENSDART00000099880
wingless-type MMTV integration site family, member 11, related
chr7_+_39444843 2.63 ENSDART00000143999
ENSDART00000173554
ENSDART00000173698
ENSDART00000173754
ENSDART00000144075
ENSDART00000138192
ENSDART00000145457
ENSDART00000141750
ENSDART00000103056
ENSDART00000142946
ENSDART00000173748
troponin T type 3b (skeletal, fast)
chr7_+_44713135 2.58 ENSDART00000170721
si:dkey-56m19.5
chr9_-_45601103 2.57 ENSDART00000180465
anterior gradient 1
chr4_+_12031958 2.53 ENSDART00000044154
troponin T2c, cardiac
chr3_+_23721808 2.49 ENSDART00000012470
homeobox B4a
chr2_-_30668580 2.48 ENSDART00000087270
catenin (cadherin-associated protein), delta 2b
chr23_-_45705525 2.45 ENSDART00000148959
endothelin receptor type Ab
chr13_-_39159810 2.44 ENSDART00000131508
collagen, type IX, alpha 1b
chr5_-_65021156 2.43 ENSDART00000166183
annexin A1c
chr25_+_31323978 2.41 ENSDART00000067030
lymphocyte-specific protein 1
chr9_-_3671911 2.40 ENSDART00000102900
Sp5 transcription factor a
chr12_+_6041575 2.38 ENSDART00000091868
glucose-6-phosphatase a, catalytic subunit, tandem duplicate 2
chr5_+_35458190 2.38 ENSDART00000051313
fructose-1,6-bisphosphatase 1b
chr4_-_77432218 2.35 ENSDART00000158683
solute carrier organic anion transporter family, member 1D1
chr5_+_42280372 2.33 ENSDART00000142855
T-box 6, like
chr18_-_23874929 2.33 ENSDART00000134910
nuclear receptor subfamily 2, group F, member 2
chr6_-_45905746 2.28 ENSDART00000025428
eph receptor A2 a
chr20_+_10538025 2.28 ENSDART00000129762
serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like
chr8_+_13106760 2.27 ENSDART00000029308
integrin, beta 4
chr11_+_6116503 2.25 ENSDART00000176170
nuclear receptor subfamily 2, group F, member 6b
chr24_-_33703504 2.24 ENSDART00000079292
caveolae associated protein 4b
chr15_-_3736773 2.23 ENSDART00000090624
lysophosphatidic acid receptor 6a
chr23_-_35694171 2.22 ENSDART00000077539
tubulin, alpha 1c
chr2_-_32768951 2.19 ENSDART00000004712
beaded filament structural protein 2, phakinin
chr4_-_211714 2.18 ENSDART00000172566
protein tyrosine phosphatase, receptor type, O
chr24_+_25069609 2.17 ENSDART00000115165
APC membrane recruitment protein 2
chr22_+_13917311 2.17 ENSDART00000022654
SH3-domain binding protein 4a
chr9_+_25568839 2.15 ENSDART00000177342
zinc finger E-box binding homeobox 2a
chr13_-_39160018 2.13 ENSDART00000168795
collagen, type IX, alpha 1b
chr18_-_23875219 2.13 ENSDART00000059976
nuclear receptor subfamily 2, group F, member 2
chr8_-_22964486 2.12 ENSDART00000112381
elastin microfibril interfacer 3a
chr25_-_31423493 2.09 ENSDART00000027661
myogenic differentiation 1
chr22_-_16042243 2.08 ENSDART00000062633
sphingosine-1-phosphate receptor 1
chr5_-_67471375 2.06 ENSDART00000147009
si:dkey-251i10.2
chr21_+_24287403 2.06 ENSDART00000111169
cell adhesion molecule 1a
chr23_-_26077038 2.04 ENSDART00000126299
GDP dissociation inhibitor 1
chr10_-_29816467 2.03 ENSDART00000055913
histone 2, H2, like
chr21_-_19006631 2.02 ENSDART00000080269
ENSDART00000191682
phosphoglycerate mutase 2 (muscle)
chr20_-_40370736 2.01 ENSDART00000041229
fatty acid binding protein 7, brain, b
chr21_-_37194365 2.01 ENSDART00000100286
fibroblast growth factor receptor 4
chr24_+_4977862 2.00 ENSDART00000114537
zic family member 4
chr15_-_21877726 2.00 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
chr7_+_38750871 2.00 ENSDART00000114238
ENSDART00000052325
ENSDART00000137001
coagulation factor II (thrombin)
chr25_+_21829777 1.98 ENSDART00000027393
creatine kinase, mitochondrial 1
chr8_-_16697912 1.97 ENSDART00000076542
retinal pigment epithelium-specific protein 65b
chr12_+_6465557 1.96 ENSDART00000066477
ENSDART00000122271
dickkopf WNT signaling pathway inhibitor 1b
chr9_+_54178475 1.94 ENSDART00000104475
thymosin, beta 4 x
chr6_+_29791164 1.94 ENSDART00000017424
prothymosin, alpha a
chr6_-_26559921 1.91 ENSDART00000104532
SRY (sex determining region Y)-box 14
chr2_-_8017579 1.91 ENSDART00000040209
eph receptor B3a
chr24_+_4978055 1.91 ENSDART00000045813
zic family member 4
chr1_-_50710468 1.91 ENSDART00000080389
family with sequence similarity 13, member A
chr14_-_41285392 1.90 ENSDART00000147389
transmembrane protein 35
chr5_-_41531629 1.88 ENSDART00000051082
aldo-keto reductase family 1, member A1a (aldehyde reductase)
chr4_-_11580948 1.88 ENSDART00000049066
neuroepithelial cell transforming 1
chr3_+_41922114 1.86 ENSDART00000138280
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_-_16562505 1.86 ENSDART00000156406
ATPase Na+/K+ transporting subunit beta 3a
chr25_-_22187397 1.86 ENSDART00000123211
ENSDART00000139110
plakophilin 3a
chr6_-_32093830 1.85 ENSDART00000017695
forkhead box D3
chr6_-_43092175 1.85 ENSDART00000084389
leucine rich repeat neuronal 1
chr25_+_18964782 1.84 ENSDART00000017299
thymine DNA glycosylase, tandem duplicate 1
chr4_-_25064510 1.83 ENSDART00000025153
GATA binding protein 3
chr23_+_27068225 1.83 ENSDART00000054238
major intrinsic protein of lens fiber a
chr3_-_46817499 1.82 ENSDART00000013717
ELAV like neuron-specific RNA binding protein 3
chr14_-_21064199 1.82 ENSDART00000172099
si:dkey-74k8.3
chr17_+_52822831 1.82 ENSDART00000193368
Meis homeobox 2a
chr3_+_15809098 1.81 ENSDART00000183023
phosphatase, orphan 1
chr7_-_69636502 1.81 ENSDART00000126739
tetraspanin 5a
chr18_+_24922125 1.81 ENSDART00000180385
repulsive guidance molecule family member a
chr21_-_37194669 1.80 ENSDART00000192748
fibroblast growth factor receptor 4
chr15_-_18067220 1.80 ENSDART00000113142
pleckstrin homology-like domain, family B, member 1b
chr25_-_18953322 1.80 ENSDART00000155927
si:ch211-68a17.7
chr8_-_41228530 1.79 ENSDART00000165949
ENSDART00000173055
fumarylacetoacetate hydrolase domain containing 2A
chr6_-_35487413 1.78 ENSDART00000102461
regulator of G protein signaling 8
chr19_-_14191592 1.78 ENSDART00000164594
T-box transcription factor Ta
chr12_-_31103187 1.78 ENSDART00000005562
ENSDART00000031408
ENSDART00000125046
ENSDART00000009237
ENSDART00000122972
ENSDART00000153068
transcription factor 7 like 2
chr24_-_26328721 1.78 ENSDART00000125468
apolipoprotein Db
chr5_-_28679135 1.76 ENSDART00000193585
tenascin C
chr23_-_46040618 1.76 ENSDART00000161415

chr13_+_23157053 1.76 ENSDART00000162359
sorbin and SH3 domain containing 1
chr24_-_32408404 1.75 ENSDART00000144157
si:ch211-56a11.2
chr18_-_494606 1.75 ENSDART00000157564
WT1 interacting protein
chr5_-_64168415 1.72 ENSDART00000048395
cardiac myosin light chain-1
chr1_+_17593392 1.72 ENSDART00000078889
helt bHLH transcription factor
chr9_-_7684002 1.72 ENSDART00000016360
si:ch73-199e17.1
chr4_+_12612145 1.71 ENSDART00000181201
LIM domain only 3
chr23_+_24705424 1.71 ENSDART00000104029
C1q and TNF related 12
chr14_-_21063977 1.70 ENSDART00000164373
si:dkey-74k8.3
chr9_-_1970071 1.70 ENSDART00000080608
homeobox D10a
chr15_+_28368644 1.70 ENSDART00000168453
solute carrier family 43 (amino acid system L transporter), member 2a
chr3_-_8510201 1.69 ENSDART00000009151

chr13_-_7766758 1.68 ENSDART00000171831
H2A histone family, member Y2
chr14_-_1990290 1.67 ENSDART00000183382
protocadherin 2 gamma 5
chr8_+_19668654 1.67 ENSDART00000091436
forkhead box E3
chr9_+_54179306 1.66 ENSDART00000189829
thymosin, beta 4 x
chr18_-_6634424 1.66 ENSDART00000062423
ENSDART00000179955
troponin I, skeletal, slow c
chr9_-_42696408 1.66 ENSDART00000144744
collagen, type V, alpha 2a
chr5_+_10014604 1.65 ENSDART00000092333
solute carrier family 2 (facilitated glucose transporter), member 11b
chr12_+_27129659 1.64 ENSDART00000076161
homeobox B5b
chr4_+_12615836 1.63 ENSDART00000003583
LIM domain only 3
chr2_+_33368414 1.62 ENSDART00000077462
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr7_-_41554047 1.62 ENSDART00000174144
plexin domain containing 2
chr2_-_43653015 1.62 ENSDART00000148454
integrin, beta 1b.2
chr20_-_22484621 1.62 ENSDART00000063601
GS homeobox 2
chr2_-_28102264 1.62 ENSDART00000013638
cadherin 6
chr17_+_52822422 1.61 ENSDART00000158273
ENSDART00000161414
Meis homeobox 2a
chr2_-_21349425 1.58 ENSDART00000171699
hedgehog acyltransferase like, a
chr16_+_32995882 1.58 ENSDART00000170157
protease, serine, 35
chr3_+_14611299 1.58 ENSDART00000140577
tetraspanin 35
chr14_-_36863432 1.57 ENSDART00000158052
ring finger protein 130
chr10_-_17466990 1.57 ENSDART00000147794
5'-nucleotidase, cytosolic II, like 1
chr20_+_22666548 1.55 ENSDART00000147520
ligand of numb-protein X 1
chr2_+_38161318 1.55 ENSDART00000044264
matrix metallopeptidase 14b (membrane-inserted)
chr3_-_29977495 1.55 ENSDART00000077111
hydroxysteroid (17-beta) dehydrogenase 14
chr25_-_12788370 1.54 ENSDART00000158551
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr4_-_16354292 1.52 ENSDART00000139919
lumican
chr11_-_30138299 1.52 ENSDART00000172106
Scm polycomb group protein like 2
chr8_+_46217861 1.52 ENSDART00000038790
angiopoietin-like 7
chr20_+_6630540 1.52 ENSDART00000138361
tensin 3, tandem duplicate 2
chr14_+_36231126 1.52 ENSDART00000141766
ELOVL fatty acid elongase 6
chr1_+_119960 1.51 ENSDART00000013209
coagulation factor VII
chr1_+_26356360 1.50 ENSDART00000113020
tet methylcytosine dioxygenase 2
chr23_+_36083529 1.49 ENSDART00000053295
ENSDART00000130260
homeobox C10a
chr2_+_26179096 1.49 ENSDART00000024662
phospholipid phosphatase related 3a
chr22_-_13851297 1.49 ENSDART00000080306
S100 calcium binding protein, beta (neural)
chr21_-_20328375 1.48 ENSDART00000079593
solute carrier family 26 (anion exchanger), member 1
chr7_-_60831082 1.48 ENSDART00000073654
ENSDART00000136999
pyruvate carboxylase b
chr21_+_7582036 1.47 ENSDART00000135485
ENSDART00000027268
orthopedia homeobox a
chr10_+_43994471 1.47 ENSDART00000138242
ENSDART00000186359
claudin 5b
chr13_+_29771463 1.47 ENSDART00000134424
ENSDART00000138332
ENSDART00000134330
ENSDART00000160944
ENSDART00000076992
ENSDART00000160921
paired box 2a
chr8_-_30791266 1.46 ENSDART00000062220
glutathione S-transferase theta 1a
chr5_+_67662430 1.46 ENSDART00000137700
ENSDART00000142586
si:dkey-70b23.2
chr21_-_41147818 1.46 ENSDART00000167339
ENSDART00000192730
muscle segment homeobox 2b
chr8_+_14158021 1.45 ENSDART00000080832
si:dkey-6n6.2
chr7_-_17028015 1.44 ENSDART00000022441
developing brain homeobox 1a
chr23_-_3758637 1.44 ENSDART00000131536
ENSDART00000139408
ENSDART00000137826
high mobility group AT-hook 1a
chr24_-_40700596 1.43 ENSDART00000162635
slow myosin heavy chain 2
chr11_-_23219367 1.43 ENSDART00000003646
opticin
chr24_+_24014880 1.42 ENSDART00000041335
chondrolectin
chr6_+_54711306 1.42 ENSDART00000074605
plakophilin 1b
chr11_+_44548209 1.42 ENSDART00000181798
ENSDART00000191742
ENSDART00000168209
nidogen 1b
chr10_+_43189325 1.42 ENSDART00000185584
versican b
chr2_+_29976419 1.42 ENSDART00000056748
engrailed homeobox 2b
chr20_+_26702377 1.41 ENSDART00000077753
forkhead box C1b
chr8_-_30791089 1.41 ENSDART00000147332
glutathione S-transferase theta 1a
chr22_-_20126230 1.41 ENSDART00000138688
cAMP responsive element binding protein 3-like 3a
chr16_-_24612871 1.40 ENSDART00000155614
ENSDART00000154787
ENSDART00000155983
ENSDART00000156519
FXYD domain containing ion transport regulator 6 like
chr1_+_12767318 1.40 ENSDART00000162652
protocadherin 10a
chr20_+_30445971 1.40 ENSDART00000153150
myelin transcription factor 1-like, a
chr4_-_8611841 1.38 ENSDART00000067322
F-box and leucine-rich repeat protein 14b
chr1_+_36674584 1.38 ENSDART00000186772
ENSDART00000192274
endothelin receptor type Aa
chr15_-_26549693 1.36 ENSDART00000186432
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr2_+_27010439 1.36 ENSDART00000030547
cadherin 7a
chr7_-_52417777 1.35 ENSDART00000110265
myocardial zonula adherens protein
chr21_-_36972127 1.35 ENSDART00000100310
drebrin 1
chr12_+_42574148 1.35 ENSDART00000157855
early B cell factor 3a
chr11_-_18705303 1.35 ENSDART00000059732
inhibitor of DNA binding 1
chr11_-_37120954 1.35 ENSDART00000172074
si:ch1073-278o19.1
chr8_+_16004551 1.35 ENSDART00000165141
ELAV like neuron-specific RNA binding protein 4
chr5_-_31904562 1.34 ENSDART00000140640
coronin, actin binding protein, 1Cb
chr5_+_38596630 1.34 ENSDART00000015136
monoacylglycerol O-acyltransferase 3b
chr24_-_4450238 1.34 ENSDART00000066835
frizzled class receptor 8a
chr10_+_18952271 1.33 ENSDART00000146517
dihydropyrimidinase-like 2b
chr5_+_27442247 1.33 ENSDART00000184129
lysyl oxidase-like 2b
chr5_-_46329880 1.32 ENSDART00000156577
si:ch211-130m23.5
chr6_-_40098641 1.30 ENSDART00000017402
inositol hexakisphosphate kinase 2b
chr2_-_5135125 1.29 ENSDART00000164039
prothymosin, alpha b
chr8_-_34052019 1.29 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pre-B-cell leukemia homeobox 3b
chr8_-_17064243 1.29 ENSDART00000185313
RAB3C, member RAS oncogene family
chr21_+_23953181 1.29 ENSDART00000145541
ENSDART00000065599
ENSDART00000112869
cell adhesion molecule 1a
chr22_+_16497670 1.28 ENSDART00000014330
immediate early response 5
chr15_+_28368823 1.27 ENSDART00000142298
solute carrier family 43 (amino acid system L transporter), member 2a
chr1_+_36665555 1.27 ENSDART00000128557
ENSDART00000010632
endothelin receptor type Aa
chr11_+_30295582 1.26 ENSDART00000122424
UDP glucuronosyltransferase 1 family, polypeptide B7

Network of associatons between targets according to the STRING database.

First level regulatory network of lef1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.8 GO:0060843 lymphatic endothelial cell fate commitment(GO:0060838) venous endothelial cell differentiation(GO:0060843) venous endothelial cell fate commitment(GO:0060845)
1.3 3.8 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
1.1 3.2 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
1.0 5.2 GO:0010872 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
1.0 4.1 GO:0042985 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
0.8 3.2 GO:1901825 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.8 2.4 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.8 2.4 GO:0005985 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.7 2.2 GO:0007398 ectoderm development(GO:0007398)
0.7 3.5 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.7 2.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.7 2.1 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.7 4.1 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.6 1.9 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.6 2.5 GO:2000583 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.6 2.5 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.6 4.3 GO:0045582 positive regulation of T cell differentiation(GO:0045582)
0.6 1.8 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.6 1.8 GO:0010159 specification of organ position(GO:0010159)
0.6 2.4 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.6 1.8 GO:0045887 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.6 3.5 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.6 3.9 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.5 1.6 GO:0006589 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.5 2.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.5 1.6 GO:1903060 N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.5 3.6 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.5 16.4 GO:0060030 dorsal convergence(GO:0060030)
0.5 2.0 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.5 1.9 GO:1990697 protein depalmitoleylation(GO:1990697)
0.5 6.0 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.4 2.2 GO:0097066 response to thyroid hormone(GO:0097066)
0.4 1.8 GO:0010226 response to lithium ion(GO:0010226)
0.4 1.7 GO:0061032 visceral serous pericardium development(GO:0061032)
0.4 1.7 GO:0046324 regulation of glucose import(GO:0046324)
0.4 1.6 GO:0060080 inhibitory postsynaptic potential(GO:0060080) regulation of synaptic transmission, glycinergic(GO:0060092)
0.4 2.8 GO:0060017 parathyroid gland development(GO:0060017)
0.4 2.0 GO:0006953 acute-phase response(GO:0006953)
0.4 1.6 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.4 1.9 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.4 1.1 GO:0042730 fibrinolysis(GO:0042730)
0.4 1.5 GO:0019532 oxalate transport(GO:0019532)
0.4 1.8 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.4 3.6 GO:0042989 sequestering of actin monomers(GO:0042989)
0.3 1.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.3 1.9 GO:0055016 hypochord development(GO:0055016)
0.3 1.5 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.3 0.9 GO:0097264 self proteolysis(GO:0097264)
0.3 1.8 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.3 1.2 GO:0002568 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.3 1.2 GO:0016554 cytidine to uridine editing(GO:0016554) regulation of anterior head development(GO:2000742)
0.3 0.9 GO:0034368 protein-lipid complex remodeling(GO:0034368) plasma lipoprotein particle remodeling(GO:0034369) high-density lipoprotein particle remodeling(GO:0034375)
0.3 0.9 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.3 1.4 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.3 2.2 GO:0033292 T-tubule organization(GO:0033292)
0.3 1.4 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.3 2.4 GO:0060114 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.3 1.0 GO:0097037 heme export(GO:0097037)
0.3 1.6 GO:0022029 telencephalon cell migration(GO:0022029)
0.3 3.0 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.2 2.0 GO:0006833 water transport(GO:0006833)
0.2 1.2 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.2 1.0 GO:0086005 ventricular cardiac muscle cell action potential(GO:0086005)
0.2 0.7 GO:1902893 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.2 0.7 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 0.7 GO:0021571 rhombomere 5 development(GO:0021571) rhombomere 6 development(GO:0021572)
0.2 1.9 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.2 1.3 GO:0033986 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.2 0.4 GO:0051228 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.2 1.5 GO:0006211 5-methylcytosine catabolic process(GO:0006211) 5-methylcytosine metabolic process(GO:0019857)
0.2 0.4 GO:0044273 sulfur compound catabolic process(GO:0044273)
0.2 0.6 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.2 0.8 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.2 2.9 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 1.4 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.2 0.6 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.2 2.2 GO:0010002 cardioblast differentiation(GO:0010002)
0.2 6.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 2.0 GO:0003197 endocardial cushion development(GO:0003197)
0.2 8.0 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 1.6 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.2 0.6 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.2 1.9 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.2 0.6 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 2.1 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.2 0.7 GO:0048914 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.2 0.5 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.2 0.7 GO:0060437 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.2 1.0 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.2 0.7 GO:0034969 histone arginine methylation(GO:0034969)
0.2 0.6 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.2 2.0 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.2 1.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.2 0.9 GO:0021982 pineal gland development(GO:0021982)
0.2 4.8 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 0.4 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.7 GO:0031179 peptide modification(GO:0031179)
0.1 1.0 GO:0034389 lipid particle organization(GO:0034389)
0.1 2.5 GO:0097178 ruffle assembly(GO:0097178)
0.1 1.3 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.7 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.1 3.9 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.9 GO:0003207 cardiac chamber formation(GO:0003207)
0.1 9.8 GO:0006941 striated muscle contraction(GO:0006941)
0.1 1.1 GO:0060386 synapse assembly involved in innervation(GO:0060386)
0.1 1.0 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 0.5 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 1.0 GO:0050482 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 1.2 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.1 2.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 2.6 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 1.2 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 0.3 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.3 GO:0055057 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103) neuroblast division(GO:0055057)
0.1 0.8 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 0.7 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.6 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1 0.5 GO:0045124 regulation of bone resorption(GO:0045124)
0.1 0.7 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.1 0.6 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 0.8 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 1.9 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 1.2 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 0.5 GO:0019482 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.1 1.0 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.4 GO:0035909 aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.1 1.2 GO:0042572 retinol metabolic process(GO:0042572)
0.1 1.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.1 1.9 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.1 0.6 GO:0046292 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.1 1.8 GO:0048570 notochord morphogenesis(GO:0048570)
0.1 0.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.5 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 0.4 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 1.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 0.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.7 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.6 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 1.5 GO:0046686 response to cadmium ion(GO:0046686)
0.1 2.0 GO:0007520 myoblast fusion(GO:0007520)
0.1 3.6 GO:0060402 cytosolic calcium ion transport(GO:0060401) calcium ion transport into cytosol(GO:0060402)
0.1 0.7 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.4 GO:0060584 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.5 GO:0001780 neutrophil homeostasis(GO:0001780)
0.1 2.4 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.1 1.8 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.1 3.9 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.1 0.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.8 GO:0003139 secondary heart field specification(GO:0003139) regulation of organ growth(GO:0046620)
0.1 1.0 GO:0016203 muscle attachment(GO:0016203)
0.1 1.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 2.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 1.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.7 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.5 GO:0051013 microtubule severing(GO:0051013)
0.1 0.7 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.1 0.7 GO:0034394 protein localization to cell surface(GO:0034394) energy homeostasis(GO:0097009)
0.1 0.7 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 2.6 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 1.1 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 0.9 GO:0061074 regulation of neural retina development(GO:0061074)
0.1 0.5 GO:0021654 rhombomere boundary formation(GO:0021654)
0.1 0.2 GO:0097501 detoxification of zinc ion(GO:0010312) stress response to metal ion(GO:0097501) stress response to zinc ion(GO:1990359)
0.1 0.5 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 0.8 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.1 2.2 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.5 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 1.8 GO:0007568 aging(GO:0007568)
0.1 0.5 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 1.9 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.2 GO:0034103 regulation of tissue remodeling(GO:0034103)
0.1 0.3 GO:0045471 response to ethanol(GO:0045471)
0.1 0.4 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 1.0 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 1.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.8 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.0 0.2 GO:0030224 monocyte differentiation(GO:0030224)
0.0 1.4 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.5 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.0 0.7 GO:0018149 peptide cross-linking(GO:0018149)
0.0 6.2 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.0 0.4 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.0 0.7 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 9.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.5 GO:0046849 bone remodeling(GO:0046849)
0.0 0.4 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332) muscle cell fate specification(GO:0042694) adipose tissue development(GO:0060612)
0.0 0.6 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.9 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.0 1.1 GO:0021510 spinal cord development(GO:0021510)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 1.0 GO:0021761 limbic system development(GO:0021761)
0.0 1.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.6 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 2.3 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.9 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 0.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 1.5 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.4 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.3 GO:1901998 toxin transport(GO:1901998)
0.0 4.0 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.7 GO:0009409 response to cold(GO:0009409)
0.0 0.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 1.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 2.4 GO:0031101 fin regeneration(GO:0031101)
0.0 0.4 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.4 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.5 GO:0050890 cognition(GO:0050890)
0.0 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.7 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 1.5 GO:0048332 mesoderm morphogenesis(GO:0048332)
0.0 0.3 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.3 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 2.9 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 1.0 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.3 GO:0030431 sleep(GO:0030431)
0.0 0.5 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.3 GO:0030534 adult behavior(GO:0030534)
0.0 0.5 GO:0045047 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.3 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 1.5 GO:0001708 cell fate specification(GO:0001708)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.7 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.6 GO:0008272 sulfate transport(GO:0008272)
0.0 0.1 GO:1901376 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.0 0.3 GO:0045161 neuronal ion channel clustering(GO:0045161) clustering of voltage-gated sodium channels(GO:0045162)
0.0 2.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.6 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 1.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.3 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.0 1.8 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.6 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.7 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 1.9 GO:0007623 circadian rhythm(GO:0007623)
0.0 0.2 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.2 GO:0003416 endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.0 0.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.8 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.7 GO:0048278 vesicle docking(GO:0048278)
0.0 0.1 GO:0060292 long term synaptic depression(GO:0060292)
0.0 1.5 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.3 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.4 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.2 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.4 GO:0048048 embryonic eye morphogenesis(GO:0048048)
0.0 0.1 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.8 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.5 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.0 0.5 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 2.7 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.3 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.8 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 3.5 GO:0001654 eye development(GO:0001654)
0.0 0.4 GO:2001056 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043280) positive regulation of cysteine-type endopeptidase activity(GO:2001056)
0.0 0.1 GO:0034205 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.0 GO:0045095 keratin filament(GO:0045095)
0.4 1.8 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.4 1.7 GO:0005588 collagen type V trimer(GO:0005588)
0.4 5.2 GO:0042627 chylomicron(GO:0042627)
0.2 1.0 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.2 0.9 GO:0060171 stereocilium membrane(GO:0060171)
0.2 9.4 GO:0005861 troponin complex(GO:0005861)
0.2 1.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.2 2.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 0.6 GO:1990909 Wnt signalosome(GO:1990909)
0.2 3.0 GO:0030057 desmosome(GO:0030057)
0.1 5.5 GO:0043204 perikaryon(GO:0043204)
0.1 0.5 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.8 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 5.7 GO:0008305 integrin complex(GO:0008305)
0.1 0.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.8 GO:0071256 translocon complex(GO:0071256)
0.1 0.3 GO:0033268 node of Ranvier(GO:0033268)
0.1 1.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 7.2 GO:0005882 intermediate filament(GO:0005882)
0.1 1.6 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.7 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 1.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.5 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 2.3 GO:0031012 extracellular matrix(GO:0031012)
0.1 5.4 GO:0005581 collagen trimer(GO:0005581)
0.1 2.7 GO:0016342 catenin complex(GO:0016342)
0.1 2.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.1 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 2.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 2.3 GO:0030175 filopodium(GO:0030175)
0.0 1.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.7 GO:0045180 basal cortex(GO:0045180)
0.0 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 1.7 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.5 GO:0046930 pore complex(GO:0046930)
0.0 2.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.3 GO:0032300 mismatch repair complex(GO:0032300)
0.0 2.3 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0000812 Swr1 complex(GO:0000812)
0.0 1.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.7 GO:0043195 terminal bouton(GO:0043195)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.8 GO:0030141 secretory granule(GO:0030141)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.7 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 1.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 2.0 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.4 GO:0070382 exocytic vesicle(GO:0070382)
0.0 1.5 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 19.6 GO:0005576 extracellular region(GO:0005576)
0.0 2.6 GO:0030425 dendrite(GO:0030425)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 10.0 GO:0001972 retinoic acid binding(GO:0001972)
1.0 5.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.8 3.2 GO:0050251 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.8 2.4 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.7 5.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.7 2.0 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.6 2.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.6 8.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.5 1.6 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.5 7.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.5 2.1 GO:0016521 pituitary adenylate cyclase activating polypeptide activity(GO:0016521)
0.5 1.5 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.5 1.9 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.5 5.2 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.5 1.9 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.4 2.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.4 2.0 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.4 2.0 GO:0039706 co-receptor binding(GO:0039706)
0.4 1.2 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.4 1.9 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.4 1.5 GO:0044548 S100 protein binding(GO:0044548)
0.3 3.0 GO:0008263 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.3 1.0 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.3 1.6 GO:0019960 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3 2.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 2.1 GO:0070888 E-box binding(GO:0070888)
0.3 3.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 0.9 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.3 1.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.3 1.9 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.2 4.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 0.7 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.2 0.7 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.2 2.0 GO:0015250 water channel activity(GO:0015250)
0.2 1.5 GO:0030274 LIM domain binding(GO:0030274)
0.2 0.9 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.2 1.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 0.9 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.2 2.9 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.2 0.8 GO:0070052 collagen V binding(GO:0070052)
0.2 1.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 1.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 0.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 0.7 GO:0031781 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.2 4.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 1.9 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.2 2.0 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 3.0 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 2.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 1.9 GO:0010851 cyclase regulator activity(GO:0010851)
0.1 2.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.8 GO:0019215 intermediate filament binding(GO:0019215)
0.1 3.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.3 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 2.0 GO:0005504 fatty acid binding(GO:0005504)
0.1 1.0 GO:0015232 heme transporter activity(GO:0015232)
0.1 2.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.8 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 0.6 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
0.1 1.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.7 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 1.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 3.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 3.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 1.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.6 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.5 GO:0015288 porin activity(GO:0015288)
0.1 0.4 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 0.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 1.8 GO:0015026 coreceptor activity(GO:0015026)
0.1 1.1 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 1.9 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.6 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.1 1.6 GO:0035497 cAMP response element binding(GO:0035497)
0.1 4.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.5 GO:0005030 neurotrophin receptor activity(GO:0005030) neurotrophin binding(GO:0043121)
0.1 0.7 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.8 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.5 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 3.7 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 3.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 4.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 0.5 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 0.3 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 1.0 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 1.1 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.2 GO:0072545 tyrosine binding(GO:0072545)
0.1 0.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.4 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.4 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 0.3 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1 1.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.3 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 2.2 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.1 0.7 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 1.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.3 GO:0004362 glutathione-disulfide reductase activity(GO:0004362) peptide disulfide oxidoreductase activity(GO:0015037) glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.5 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.0 0.2 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 1.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 3.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.6 GO:0016917 GABA receptor activity(GO:0016917)
0.0 2.3 GO:0005178 integrin binding(GO:0005178)
0.0 1.2 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 4.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.0 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 1.0 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 4.3 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 50.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.5 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.6 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 23.7 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.5 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 1.0 GO:0044325 ion channel binding(GO:0044325)
0.0 0.4 GO:0048038 quinone binding(GO:0048038)
0.0 2.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 2.8 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.8 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0031420 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.0 0.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 5.3 GO:0051015 actin filament binding(GO:0051015)
0.0 0.8 GO:0008009 chemokine activity(GO:0008009) chemokine receptor binding(GO:0042379)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 6.3 GO:0008289 lipid binding(GO:0008289)
0.0 1.8 GO:0005179 hormone activity(GO:0005179)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.6 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 2.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 2.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 2.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 1.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 5.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.8 PID IL27 PATHWAY IL27-mediated signaling events
0.1 1.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.7 PID REELIN PATHWAY Reelin signaling pathway
0.1 0.8 PID CONE PATHWAY Visual signal transduction: Cones
0.1 1.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.6 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 2.0 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.7 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.9 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 PID ATR PATHWAY ATR signaling pathway
0.0 0.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.8 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.3 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.8 PID RB 1PATHWAY Regulation of retinoblastoma protein

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.5 3.8 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.4 3.9 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 1.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 2.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 2.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 1.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 3.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 2.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 0.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 0.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 4.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 0.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.7 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 0.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 2.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 2.5 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 1.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)