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PRJNA195909:zebrafish embryo and larva development

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Results for lmx1ba+lmx1bb_lmx1al

Z-value: 0.68

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Transcription factors associated with lmx1ba+lmx1bb_lmx1al

Gene Symbol Gene ID Gene Info
lmx1bb
ENSDARG00000068365 LIM homeobox transcription factor 1, beta b
lmx1ba
ENSDARG00000104815 LIM homeobox transcription factor 1, beta a
lmx1al
ENSDARG00000077915 LIM homeobox transcription factor 1, alpha-like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lmx1bbdr11_v1_chr8_-_33381913_33381913-0.314.2e-01Click!
lmx1badr11_v1_chr5_-_5147041_5147041-0.284.6e-01Click!
lmx1aldr11_v1_chr3_+_52806347_52806441-0.196.3e-01Click!

Activity profile of lmx1ba+lmx1bb_lmx1al motif

Sorted Z-values of lmx1ba+lmx1bb_lmx1al motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_35830625 1.52 ENSDART00000180028
CU459056.1

chr16_+_23961276 1.07 ENSDART00000192754
apoeb
apolipoprotein Eb
chr11_-_45138857 1.04 ENSDART00000166501
cant1b
calcium activated nucleotidase 1b
chr18_+_24921587 0.98 ENSDART00000191345
rgma
repulsive guidance molecule family member a
chr2_+_33326522 0.89 ENSDART00000056655
klf17
Kruppel-like factor 17
chr11_-_41853874 0.89 ENSDART00000002556
mrto4
MRT4 homolog, ribosome maturation factor
chr3_+_46635527 0.87 ENSDART00000153971
si:dkey-248g21.1
si:dkey-248g21.1
chr14_+_45406299 0.83 ENSDART00000173142
ENSDART00000112377
map1lc3cl
microtubule-associated protein 1 light chain 3 gamma, like
chr24_+_9412450 0.81 ENSDART00000132724
si:ch211-285f17.1
si:ch211-285f17.1
chr18_-_33979693 0.78 ENSDART00000021215
si:ch211-203b20.7
si:ch211-203b20.7
chr16_+_23431189 0.78 ENSDART00000004679
icn
ictacalcin
chr24_-_21923930 0.74 ENSDART00000131944
tagln3b
transgelin 3b
chr17_+_30369396 0.64 ENSDART00000076611
greb1
growth regulation by estrogen in breast cancer 1
chr11_+_35050253 0.64 ENSDART00000124800
fam212aa
family with sequence similarity 212, member Aa
chr4_+_306036 0.64 ENSDART00000103659
msgn1
mesogenin 1
chr24_-_6078222 0.61 ENSDART00000146830
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr1_-_5455498 0.60 ENSDART00000040368
ENSDART00000114035
mnx2b
motor neuron and pancreas homeobox 2b
chr16_+_33902006 0.57 ENSDART00000161807
ENSDART00000159474
gnl2
guanine nucleotide binding protein-like 2 (nucleolar)
chr13_+_27232848 0.56 ENSDART00000138043
rin2
Ras and Rab interactor 2
chr7_+_56577906 0.55 ENSDART00000184023
hp
haptoglobin
chr7_+_19552381 0.55 ENSDART00000169060
si:ch211-212k18.5
si:ch211-212k18.5
chr18_-_19456269 0.53 ENSDART00000060363
rpl4
ribosomal protein L4
chr3_+_27798094 0.51 ENSDART00000075100
ENSDART00000151437
carhsp1
calcium regulated heat stable protein 1
chr6_+_41191482 0.50 ENSDART00000000877
opn1mw3
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr7_+_20503344 0.49 ENSDART00000157699
si:dkey-19b23.12
si:dkey-19b23.12
chr1_+_52392511 0.47 ENSDART00000144025
si:ch211-217k17.8
si:ch211-217k17.8
chr2_-_28085884 0.45 ENSDART00000131506
cdh6
cadherin 6
chr23_-_17003533 0.44 ENSDART00000080545
dnmt3bb.2
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2
chr15_-_21877726 0.44 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
zgc:162608
chr25_+_13620555 0.44 ENSDART00000163642
si:ch211-172l8.4
si:ch211-172l8.4
chr18_-_14677936 0.44 ENSDART00000111995
si:dkey-238o13.4
si:dkey-238o13.4
chr10_-_15340362 0.42 ENSDART00000148119
ENSDART00000127277
ENSDART00000154037
ENSDART00000189109
pum3
pumilio RNA-binding family member 3
chr25_-_20378721 0.42 ENSDART00000181707
kctd15a
potassium channel tetramerization domain containing 15a
chr9_+_25776971 0.42 ENSDART00000146011
zeb2a
zinc finger E-box binding homeobox 2a
chr4_-_2545310 0.42 ENSDART00000150619
ENSDART00000140760
e2f7
E2F transcription factor 7
chr2_-_7246848 0.42 ENSDART00000146434
zgc:153115
zgc:153115
chr13_+_22295905 0.42 ENSDART00000180133
ENSDART00000181125
usp54a
ubiquitin specific peptidase 54a
chr3_+_23092762 0.40 ENSDART00000142884
ENSDART00000024136
gngt2a
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr1_-_10821584 0.40 ENSDART00000167452
ENSDART00000162137
crfb15
cytokine receptor family member B15
chr16_+_29509133 0.39 ENSDART00000112116
ctss2.1
cathepsin S, ortholog2, tandem duplicate 1
chr16_+_26777473 0.39 ENSDART00000188870
cdh17
cadherin 17, LI cadherin (liver-intestine)
chr9_-_20372977 0.39 ENSDART00000113418
igsf3
immunoglobulin superfamily, member 3
chr24_-_4450238 0.38 ENSDART00000066835
fzd8a
frizzled class receptor 8a
chr10_-_43771447 0.38 ENSDART00000052307
arrdc3b
arrestin domain containing 3b
chr17_-_48944465 0.38 ENSDART00000154110
si:ch1073-80i24.3
si:ch1073-80i24.3
chr12_+_10631266 0.38 ENSDART00000161455
csf3a
colony stimulating factor 3 (granulocyte) a
chr8_+_21353878 0.37 ENSDART00000056420
alas2
aminolevulinate, delta-, synthase 2
chr15_-_22074315 0.37 ENSDART00000149830
drd2a
dopamine receptor D2a
chr17_-_26867725 0.37 ENSDART00000153590
si:dkey-221l4.10
si:dkey-221l4.10
chr18_+_3037998 0.37 ENSDART00000185844
ENSDART00000162657
rps3
ribosomal protein S3
chr4_+_16885854 0.35 ENSDART00000017726
etnk1
ethanolamine kinase 1
chr7_+_56577522 0.35 ENSDART00000149130
ENSDART00000149624
hp
haptoglobin
chr1_+_45056371 0.34 ENSDART00000073689
ENSDART00000167309
btr01
bloodthirsty-related gene family, member 1
chr2_-_30668580 0.33 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr9_-_12424791 0.33 ENSDART00000135447
ENSDART00000088199
zgc:162707
zgc:162707
chr10_+_16092671 0.33 ENSDART00000182761
ENSDART00000154835
megf10
multiple EGF-like-domains 10
chr6_+_39098397 0.32 ENSDART00000003716
ENSDART00000188655
prss60.2
protease, serine, 60.2
chr15_+_34988148 0.32 ENSDART00000076269
ccdc105
coiled-coil domain containing 105
chr4_+_72723304 0.32 ENSDART00000186791
ENSDART00000158902
ENSDART00000191925
rab3ip
RAB3A interacting protein (rabin3)
chr10_+_42423318 0.32 ENSDART00000134282
npy8ar
neuropeptide Y receptor Y8a
chr20_+_52554352 0.31 ENSDART00000153217
ENSDART00000145230
eef1db
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr5_-_41307550 0.30 ENSDART00000143446
npr3
natriuretic peptide receptor 3
chr18_+_38807239 0.30 ENSDART00000184332
fam214a
family with sequence similarity 214, member A
chr8_+_6576940 0.29 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr17_-_42492668 0.29 ENSDART00000183946
CR925755.2

chr23_-_24394719 0.28 ENSDART00000044918
epha2b
eph receptor A2 b
chr23_+_31913292 0.28 ENSDART00000136910
armc1l
armadillo repeat containing 1, like
chr10_+_7593185 0.28 ENSDART00000162617
ENSDART00000162590
ENSDART00000171744
ppp2cb
protein phosphatase 2, catalytic subunit, beta isozyme
chr8_-_23612462 0.27 ENSDART00000025024
slc38a5b
solute carrier family 38, member 5b
chr22_+_16535575 0.27 ENSDART00000083063
tal1
T-cell acute lymphocytic leukemia 1
chr8_-_19216657 0.27 ENSDART00000135096
ENSDART00000135869
ENSDART00000145951
si:ch73-222f22.2
si:ch73-222f22.2
si:ch73-222f22.2
si:ch73-222f22.2
chr1_+_52929185 0.27 ENSDART00000147683
inpp4b
inositol polyphosphate-4-phosphatase type II B
chr24_-_40860603 0.27 ENSDART00000188032
CU633479.7

chr17_+_24722646 0.27 ENSDART00000138356
mtfr1l
mitochondrial fission regulator 1-like
chr2_+_20793982 0.26 ENSDART00000014785
prg4a
proteoglycan 4a
chr9_-_1702648 0.26 ENSDART00000102934
hnrnpa3
heterogeneous nuclear ribonucleoprotein A3
chr19_-_11106315 0.26 ENSDART00000059102
arhgef1a
Rho guanine nucleotide exchange factor (GEF) 1a
chr3_-_23406964 0.26 ENSDART00000114723
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr22_+_2937485 0.26 ENSDART00000082222
ENSDART00000135507
ENSDART00000143258
cep19
centrosomal protein 19
chr14_+_33329420 0.25 ENSDART00000171090
ENSDART00000164062
sowahd
sosondowah ankyrin repeat domain family d
chr7_+_42461850 0.25 ENSDART00000190350
adamts18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr5_-_20194876 0.25 ENSDART00000122587
dao.1
D-amino-acid oxidase, tandem duplicate 1
chr4_+_31405646 0.25 ENSDART00000128732
si:rp71-5o12.3
si:rp71-5o12.3
chr3_+_1637358 0.25 ENSDART00000180266
CR394546.5

chr6_+_45918981 0.25 ENSDART00000149642
h6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr20_-_31075972 0.24 ENSDART00000122927
si:ch211-198b3.4
si:ch211-198b3.4
chr22_+_1291651 0.24 ENSDART00000159296
si:ch73-138e16.4
si:ch73-138e16.4
chr7_-_30174882 0.24 ENSDART00000110409
frmd5
FERM domain containing 5
chr22_-_6988102 0.24 ENSDART00000185618
fgfr1bl
fibroblast growth factor receptor 1b, like
chr4_+_12612145 0.24 ENSDART00000181201
lmo3
LIM domain only 3
chr23_+_11285662 0.24 ENSDART00000111028
chl1a
cell adhesion molecule L1-like a
chr15_-_43284021 0.24 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr7_+_20471315 0.24 ENSDART00000173714
si:dkey-19b23.13
si:dkey-19b23.13
chr16_-_51299061 0.24 ENSDART00000148677
serpinb1l4
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 4
chr15_-_2493771 0.23 ENSDART00000184906
neu4
sialidase 4
chr16_-_29528198 0.23 ENSDART00000150028
onecutl
one cut domain, family member, like
chr10_+_11767791 0.23 ENSDART00000092047
ppwd1
peptidylprolyl isomerase domain and WD repeat containing 1
chr24_+_21540842 0.23 ENSDART00000091529
wasf3b
WAS protein family, member 3b
chr7_+_7696665 0.23 ENSDART00000091099
ino80b
INO80 complex subunit B
chr2_+_19522082 0.22 ENSDART00000146098
pimr49
Pim proto-oncogene, serine/threonine kinase, related 49
chr22_-_12160283 0.22 ENSDART00000146785
ENSDART00000128176
tmem163b
transmembrane protein 163b
chr16_-_29387215 0.21 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr16_-_42894628 0.21 ENSDART00000045600
hfe2
hemochromatosis type 2
chr5_-_12219572 0.21 ENSDART00000167834
nos1
nitric oxide synthase 1 (neuronal)
chr17_+_23298928 0.21 ENSDART00000153652
zgc:165461
zgc:165461
chr20_-_22476255 0.21 ENSDART00000103510
pdgfra
platelet-derived growth factor receptor, alpha polypeptide
chr7_-_28148310 0.21 ENSDART00000044208
lmo1
LIM domain only 1
chr3_-_39695856 0.21 ENSDART00000148247
b9d1
B9 protein domain 1
chr8_+_23152244 0.21 ENSDART00000036801
ENSDART00000184298
slc17a9a
solute carrier family 17 (vesicular nucleotide transporter), member 9a
chr7_+_72003301 0.21 ENSDART00000012918
ENSDART00000182268
ENSDART00000185750
psmd9
proteasome 26S subunit, non-ATPase 9
chr15_+_857148 0.21 ENSDART00000156949
si:dkey-7i4.13
si:dkey-7i4.13
chr20_+_11731039 0.21 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
si:ch211-155o21.3
chr22_+_38037530 0.21 ENSDART00000012212
commd2
COMM domain containing 2
chr19_+_43119014 0.20 ENSDART00000023156
eef1a1l1
eukaryotic translation elongation factor 1 alpha 1, like 1
chr23_-_31974060 0.20 ENSDART00000168087
BX927210.1

chr20_-_37490612 0.20 ENSDART00000185458
si:ch211-202p1.5
si:ch211-202p1.5
chr16_+_23087326 0.20 ENSDART00000167518
ENSDART00000161087
efna3b
ephrin-A3b
chr23_-_16485190 0.20 ENSDART00000155038
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr16_+_13883872 0.19 ENSDART00000101304
ENSDART00000136005
atg12
ATG12 autophagy related 12 homolog (S. cerevisiae)
chr10_+_16584382 0.19 ENSDART00000112039
CR790388.1

chr10_+_21867307 0.19 ENSDART00000126629
cbln17
cerebellin 17
chr4_-_20292821 0.19 ENSDART00000136069
ENSDART00000192504
cacna2d4a
calcium channel, voltage-dependent, alpha 2/delta subunit 4a
chr3_+_17537352 0.18 ENSDART00000104549
hcrt
hypocretin (orexin) neuropeptide precursor
chr22_-_2937503 0.18 ENSDART00000092991
ENSDART00000131110
pigx
phosphatidylinositol glycan anchor biosynthesis, class X
chr24_-_30862168 0.18 ENSDART00000168540
ptbp2a
polypyrimidine tract binding protein 2a
chr8_-_12867434 0.18 ENSDART00000081657
slc2a6
solute carrier family 2 (facilitated glucose transporter), member 6
chr20_+_539852 0.17 ENSDART00000185994
dse
dermatan sulfate epimerase
chr15_-_4528326 0.17 ENSDART00000158122
ENSDART00000155619
ENSDART00000128602
tfdp2
transcription factor Dp-2
chr16_+_23913943 0.17 ENSDART00000175404
ENSDART00000129525
apoa4b.1
apolipoprotein A-IV b, tandem duplicate 1
chr17_-_23416897 0.17 ENSDART00000163391
si:ch211-149k12.3
si:ch211-149k12.3
chr23_-_6749820 0.17 ENSDART00000128772
ptges3b
prostaglandin E synthase 3b (cytosolic)
chr25_+_3058924 0.17 ENSDART00000029580
fth1b
ferritin, heavy polypeptide 1b
chr15_+_5360407 0.17 ENSDART00000110420
or112-1
odorant receptor, family A, subfamily 112, member 1
chr2_+_19633493 0.16 ENSDART00000147989
pimr54
Pim proto-oncogene, serine/threonine kinase, related 54
chr8_-_37249813 0.16 ENSDART00000098634
ENSDART00000140233
ENSDART00000061328
rbm39b
RNA binding motif protein 39b
chr11_-_40728380 0.16 ENSDART00000023745
ccdc114
coiled-coil domain containing 114
chr7_+_7048245 0.16 ENSDART00000001649
actn3b
actinin alpha 3b
chr20_-_52902693 0.16 ENSDART00000166115
ENSDART00000161050
ctsbb
cathepsin Bb
chr2_+_19578446 0.16 ENSDART00000164758
pimr50
Pim proto-oncogene, serine/threonine kinase, related 50
chr21_-_40676224 0.16 ENSDART00000162623
arxb
aristaless related homeobox b
chr22_-_8725768 0.15 ENSDART00000189873
ENSDART00000181819
si:ch73-27e22.1
si:ch73-27e22.8
si:ch73-27e22.1
si:ch73-27e22.8
chr24_-_35561672 0.15 ENSDART00000058564
mcm4
minichromosome maintenance complex component 4
chr24_+_16985181 0.15 ENSDART00000135580
eif2s3
eukaryotic translation initiation factor 2, subunit 3 gamma
chr9_-_41077934 0.15 ENSDART00000100342
ankar
ankyrin and armadillo repeat containing
chr25_+_7671640 0.14 ENSDART00000145367
kcnj11l
potassium inwardly-rectifying channel, subfamily J, member 11, like
chr4_+_22480169 0.14 ENSDART00000146272
ENSDART00000066904
ndufb2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr23_+_19813677 0.14 ENSDART00000139192
ENSDART00000142308
emd
emerin (Emery-Dreifuss muscular dystrophy)
chr20_-_43663494 0.14 ENSDART00000144564
BX470188.1

chr11_+_18873113 0.14 ENSDART00000103969
ENSDART00000103968
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr5_+_42400777 0.14 ENSDART00000183114
BX548073.8

chr1_+_33668236 0.14 ENSDART00000122316
ENSDART00000102184
arl13b
ADP-ribosylation factor-like 13b
chr1_+_12767318 0.14 ENSDART00000162652
pcdh10a
protocadherin 10a
chr1_+_34696503 0.14 ENSDART00000186106
CR339054.2

chr19_+_45962016 0.14 ENSDART00000169710
utp23
UTP23, small subunit (SSU) processome component, homolog (yeast)
chr2_+_36721357 0.13 ENSDART00000019063
pdcd10b
programmed cell death 10b
chr3_-_39696066 0.13 ENSDART00000015393
b9d1
B9 protein domain 1
chr24_-_31425799 0.13 ENSDART00000157998
cngb3.1
cyclic nucleotide gated channel beta 3, tandem duplicate 1
chr13_+_25449681 0.13 ENSDART00000101328
atoh7
atonal bHLH transcription factor 7
chr8_-_37249991 0.13 ENSDART00000189275
ENSDART00000178556
rbm39b
RNA binding motif protein 39b
chr10_+_11261576 0.13 ENSDART00000155333
hsdl2
hydroxysteroid dehydrogenase like 2
chr3_-_21094437 0.13 ENSDART00000153739
ENSDART00000109790
nlk1
nemo-like kinase, type 1
chr13_+_4225173 0.13 ENSDART00000058242
ENSDART00000143456
mea1
male-enhanced antigen 1
chr14_+_34490445 0.13 ENSDART00000132193
ENSDART00000148044
wnt8a
wingless-type MMTV integration site family, member 8a
chr10_-_33297864 0.12 ENSDART00000163360
PRDM15
PR/SET domain 15
chr5_-_42661012 0.12 ENSDART00000158339
pimr58
Pim proto-oncogene, serine/threonine kinase, related 58
chr5_-_67750907 0.12 ENSDART00000172097
b4galt4
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr13_+_45431660 0.12 ENSDART00000099950
syf2
SYF2 pre-mRNA-splicing factor
chr11_-_41220794 0.12 ENSDART00000192895
mrps16
mitochondrial ribosomal protein S16
chr17_-_11439815 0.12 ENSDART00000130105
psma3
proteasome subunit alpha 3
chr12_+_16168342 0.12 ENSDART00000079326
ENSDART00000170024
lrp2b
low density lipoprotein receptor-related protein 2b
chr4_-_43388943 0.12 ENSDART00000150796
si:dkey-29j8.2
si:dkey-29j8.2
chr18_+_19456648 0.12 ENSDART00000079695
zwilch
zwilch kinetochore protein
chr16_-_55028740 0.11 ENSDART00000156368
ENSDART00000161704
zgc:114181
zgc:114181
chr17_+_10593398 0.11 ENSDART00000168897
ENSDART00000193989
ENSDART00000191664
ENSDART00000167188
mapkbp1
mitogen-activated protein kinase binding protein 1
chr17_+_23462972 0.11 ENSDART00000112959
ENSDART00000192168
ankrd1a
ankyrin repeat domain 1a (cardiac muscle)
chr4_+_34657691 0.11 ENSDART00000158655
AL645691.1

chr4_-_1801519 0.11 ENSDART00000188604
ENSDART00000135749
nudt4b
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr6_+_52350443 0.11 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
si:ch211-239j9.1
chr14_+_30795559 0.11 ENSDART00000006132
cfl1
cofilin 1
chr17_-_10122204 0.11 ENSDART00000160751
BX088587.1

chr2_+_29842878 0.11 ENSDART00000131376
si:ch211-207d6.2
si:ch211-207d6.2
chr24_-_17067284 0.11 ENSDART00000111237
armc3
armadillo repeat containing 3
chr3_-_58798815 0.11 ENSDART00000082920
si:ch73-281f12.4
si:ch73-281f12.4
chr4_-_9891874 0.11 ENSDART00000067193
adm2a
adrenomedullin 2a
chr17_+_21964472 0.11 ENSDART00000063704
ENSDART00000188904
crip3
cysteine-rich protein 3
chr13_+_35339182 0.11 ENSDART00000019323
jag1b
jagged 1b
chr13_-_12602920 0.11 ENSDART00000102311
lrit3b
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr8_+_16758304 0.11 ENSDART00000133514
elovl7a
ELOVL fatty acid elongase 7a
chr18_-_2433011 0.11 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr2_+_43469241 0.11 ENSDART00000142078
ENSDART00000098265
nrp1b
neuropilin 1b
chr14_-_22113600 0.11 ENSDART00000113752
si:dkey-6i22.5
si:dkey-6i22.5
chr21_-_23331619 0.11 ENSDART00000007806
zbtb16a
zinc finger and BTB domain containing 16a
chr2_+_24507597 0.11 ENSDART00000133109
rps28
ribosomal protein S28
chr22_-_621609 0.11 ENSDART00000137264
ENSDART00000106636
srsf3b
serine/arginine-rich splicing factor 3b
chr1_-_46875493 0.11 ENSDART00000115081
agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr19_-_5699703 0.11 ENSDART00000082050
zgc:174904
zgc:174904
chr15_+_1796313 0.10 ENSDART00000126253
fam124b
family with sequence similarity 124B
chr4_+_12612723 0.10 ENSDART00000133767
lmo3
LIM domain only 3
chr8_+_23355484 0.10 ENSDART00000085361
ENSDART00000125729
dnmt3ba
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a
chr4_-_16334362 0.10 ENSDART00000101461
epyc
epiphycan

Network of associatons between targets according to the STRING database.

First level regulatory network of lmx1ba+lmx1bb_lmx1al

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.3 0.9 GO:0048785 hatching gland development(GO:0048785)
0.2 0.6 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.2 1.0 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.6 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.4 GO:0060898 spinal cord radial glial cell differentiation(GO:0021531) eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.1 0.3 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.1 0.4 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.4 GO:0034380 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873) high-density lipoprotein particle assembly(GO:0034380)
0.1 0.4 GO:0032875 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.1 0.2 GO:0039015 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.1 0.2 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.1 0.3 GO:0089709 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.3 GO:0046436 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.1 0.4 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.1 0.3 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.1 GO:1903441 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.0 0.2 GO:0042755 eating behavior(GO:0042755)
0.0 0.1 GO:1903358 regulation of Golgi organization(GO:1903358)
0.0 0.6 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.0 0.2 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.4 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.1 GO:0097264 self proteolysis(GO:0097264)
0.0 0.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.6 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.4 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.1 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.0 0.2 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:1901906 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0010660 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.0 0.4 GO:0008354 germ cell migration(GO:0008354)
0.0 0.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0097435 fibril organization(GO:0097435)
0.0 0.2 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.4 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0 0.4 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.3 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.4 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.1 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.0 0.2 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.0 0.3 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.1 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.0 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.0 GO:0061549 sympathetic ganglion development(GO:0061549)
0.0 0.3 GO:0060997 dendritic spine morphogenesis(GO:0060997) dendritic spine organization(GO:0097061)
0.0 0.4 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.0 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.0 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.4 GO:0043220 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.1 0.3 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.1 0.2 GO:0097189 apoptotic body(GO:0097189)
0.0 0.1 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 1.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.8 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.0 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.4 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.4 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.3 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.1 0.3 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.4 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.2 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.1 1.0 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.9 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.0 0.2 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.4 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.2 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.1 GO:0072545 tyrosine binding(GO:0072545)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.0 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.0 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 1.1 GO:0045296 cadherin binding(GO:0045296)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID BMP PATHWAY BMP receptor signaling
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 1.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)